Related ArticlesThe CFTR variant profile of Hispanic patients with cystic fibrosis: Impact on access to effective screening, diagnosis, and personalized medicine. J Genet Couns. 2020 Mar 30;: Authors: Januska MN, Marx L, Walker PA, Berdella MN, Langfelder-Schwind E Abstract Hispanic patients comprise an appreciable and increasing proportion of patients with cystic fibrosis (CF) in the United States (US). Hispanic patients with CF are known to have increased...
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Related ArticlesLactobacillus reuteri for treatment of infant colic. Acad Emerg Med. 2020 Mar 29;: Authors: Long B, Koyfman A, Gottlieb M Abstract Infant colic affects approximately 1 in 5 infants under 3 months of age and is defined by crying and/or fussing > 3 hours per day for ≥ 3 days per week. While the exact etiology is unknown, recent evidence suggests that it may be associated with adverse effects on allergies, behavior, and sleep. Other studies...
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Related Articles[German Guideline for Idiopathic Pulmonary Fibrosis]. Pneumologie. 2020 Mar 30;: Authors: Behr J, Günther A, Bonella F, Dinkel J, Fink L, Geiser T, Geißler K, Gläser S, Handzhhiev S, Jonigk D, Koschel D, Kreuter M, Leuschner G, Markart P, Prasse A, Schönfeld N, Schupp JC, Sitter H, Müller-Quernheim J, Costabel U Abstract Idiopathic pulmonary fibrosis (IPF) is a severe and often fatal disease. Diagnosis of IPF requires considerable expertise...
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Related ArticlesSlow wave activity (SWA) and sigma activities are associated with psychomotor development at eight months of age. Sleep. 2020 Mar 30;: Authors: Satomaa AL, Mäkelä T, Saarenpää-Heikkilä O, Kylliäinen A, Huupponen E, Himanen SL Abstract STUDY OBJECTIVES: The electrophysiological properties of non-rapid eye movement sleep (NREM) EEG are homeostatically modulated on global and local use-dependent levels. Furthermore, the local NREM quality...
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Related ArticlesNarcolepsy Type 1: What have we learned from immunology? Sleep. 2020 Mar 28;: Authors: Kornum BR Abstract Narcolepsy Type 1 is hypothesized to be an autoimmune disease targeting the hypocretin/orexin neurons in hypothalaus. Ample genetic and epidemiological evidence points in the direction of a pathogenesis involving the immune system, but this is not considered proof of autoimmunity. Infact, it remains a matter of debate how to prove...
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Related ArticlesA daytime nap restores hippocampal function and improves declarative learning. Sleep. 2020 Mar 28;: Authors: Ong JL, Lau TY, Lee XK, van Rijn E, Chee MWL Abstract STUDY OBJECTIVES: Daytime naps can confer benefits on subsequent declarative learning, but the physiological correlates of this improvement are less well studied. We examined learning following a daytime nap compared to an equivalent waking period using fMRI and polysomnography...
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Related ArticlesThe effects of sleep deprivation and text messaging on pedestrian safety in university students. Sleep. 2020 Mar 28;: Authors: Fobian AD, Rouse J, Stager LM, Long D, Schwebel DC, Avis KT Abstract STUDY OBJECTIVES: This study assesses the impact of sleep deprivation and text messaging on pedestrian injury risk. METHODS: Thirty-six university students engaged in a virtual reality pedestrian environment in two conditions: sleep...
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Related ArticlesTopiramate reduces nocturnal eating in sleep-related eating disorder. Sleep. 2020 Mar 30;: Authors: Winkelman JW, Wipper B, Purks J, Mei L, Schoerning L Abstract STUDY OBJECTIVES: Sleep-Related Eating Disorder (SRED) is a parasomnia characterized by partial arousals from sleep with compulsive consumption of food with impaired level of awareness and memory for the event. Small case series' have demonstrated efficacy of topiramate in SRED....
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Related ArticlesA Community Transmitted Case of Severe Acute Respiratory Distress Syndrome due to SARS CoV2 in the United States. Clin Infect Dis. 2020 Mar 30;: Authors: Sanville B, Corbett R, Pidcock W, Hardin K, Sebat C, Nguyen MV, Thompson GR, Haczku A, Schivo M, Cohen S PMID: 32227197 [PubMed - as supplied by publisher]
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Related ArticlesDifferential Activating Effects of Thyrotropin-Releasing Hormone and its Analog Taltirelin on Motor Output to the Tongue Musculature In-Vivo. Sleep. 2020 Mar 28;: Authors: Liu WY, Liu H, Aggarwal J, Huang ZL, Horner RL Abstract Thyrotropin-releasing hormone (TRH) is produced by the hypothalamus but most brain TRH is located elsewhere where it acts as a neuromodulator. TRH-positive neurons project to the hypoglossal motoneuron pool where...
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Related ArticlesA feasibility study of a mobile app to treat insomnia. Transl Behav Med. 2020 Mar 30;: Authors: Aji M, Glozier N, Bartlett D, Peters D, Calvo RA, Zheng Y, Grunstein R, Gordon C Abstract Insomnia is a major public health concern. Sleep restriction therapy (SRT) is an effective behavioral treatment but its delivery is impeded by a shortage of trained clinicians. We developed a mobile app delivering SRT to individuals with insomnia. This...
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Related ArticlesWhy Have Sleep Problems in Later-Midlife Grown Following the Great Recession? A Comparative Cohort Analysis. J Gerontol B Psychol Sci Soc Sci. 2020 Mar 30;: Authors: Bierman A Abstract OBJECTIVES: This research compares three cohorts of individuals in their fifth decade of life and examines whether sleep problems are greater in cohorts following the Great Recession. We argue that these differences will occur because post-recession cohorts...
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Related ArticlesNew insights into the cognitive effects of sleep deprivation by decomposition of a cognitive throughput task. Sleep. 2020 Mar 29;: Authors: Honn KA, Halverson T, Jackson ML, Krusmark M, Chavali VP, Gunzelmann G, Van Dongen HPA Abstract STUDY OBJECTIVES: A cognitive throughput task known as the Digit Symbol Substitution Test (DSST) (or Symbol Digit Modalities Test) has been used as an assay of general cognitive slowing during sleep deprivation....
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Related ArticlesEmerging Treatments for Malignant Pleural Mesothelioma: Where Are We Heading? Front Oncol. 2020;10:343 Authors: Cantini L, Hassan R, Sterman DH, Aerts JGJV Abstract Malignant pleural mesothelioma (MPM) is an uncommon but aggressive and treatment resistant neoplasm with low survival rates. In the last years we assisted to an exponential growth in the appreciation of mesothelioma pathobiology, leading several new treatments to be investigated...
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Related ArticlesHematopoietic stem cell transplantation in mucopolysaccharidosis type IIIA: A case description and comparison with a genotype-matched control group. Mol Genet Metab Rep. 2020 Jun;23:100578 Authors: Köhn AF, Grigull L, du Moulin M, Kabisch S, Ammer L, Rudolph C, Muschol NM Abstract Background: Mucopolysaccharidosis type IIIA (MPS IIIA, Sanfilippo A syndrome) is a chronic progressive neurodegenerative storage disorder caused by a deficiency...
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Related ArticlesAssociations of physical activity and sleep with cardiometabolic risk in older women. Prev Med Rep. 2020 Jun;18:101071 Authors: Lee J, Walker ME, Matthews KA, Kuller LH, Ranjit N, Gabriel KP Abstract In this study, we investigate the associations of objectively measured waking (sedentary, light physical activity [LPA] and moderate-to-vigorous physical activity [MVPA]) and sleep duration and quality characteristics with cardiometabolic...
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Related ArticlesEfficacy and Tolerability of Ashwagandha Root Extract in the Elderly for Improvement of General Well-being and Sleep: A Prospective, Randomized, Double-blind, Placebo-controlled Study. Cureus. 2020 Feb 23;12(2):e7083 Authors: Kelgane SB, Salve J, Sampara P, Debnath K Abstract Background Ashwagandha is an excellent adaptogen that is being used since ancient times in Ayurvedic medicine. Traditionally, it is used for various ailments and...
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Related ArticlesTargeting REV-ERBα for therapeutic purposes: promises and challenges. Theranostics. 2020;10(9):4168-4182 Authors: Wang S, Li F, Lin Y, Wu B Abstract REV-ERBα (NR1D1) is a circadian clock component that functions as a transcriptional repressor. Due to its role in direct modulation of metabolic genes, REV-ERBα is regarded as an integrator of cell metabolism with circadian clock. Accordingly, REV-ERBα is first proposed as a drug target for...
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Related ArticlesPsychological and Sleep Effects of Tryptophan and Magnesium-Enriched Mediterranean Diet in Women with Fibromyalgia. Int J Environ Res Public Health. 2020 Mar 26;17(7): Authors: Martínez-Rodríguez A, Rubio-Arias JÁ, Ramos-Campo DJ, Reche-García C, Leyva-Vela B, Nadal-Nicolás Y Abstract Anxiety, mood disturbance, eating and sleep disorders, and dissatisfaction with body image are prevalent disorders in women with fibromyalgia. The authors...
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Related ArticlesCompositional Data Analysis in Time-Use Epidemiology: What, Why, How. Int J Environ Res Public Health. 2020 Mar 26;17(7): Authors: Dumuid D, Pedišić Ž, Palarea-Albaladejo J, Martín-Fernández JA, Hron K, Olds T Abstract In recent years, the focus of activity behavior research has shifted away from univariate paradigms (e.g., physical activity, sedentary behavior and sleep) to a 24-h time-use paradigm that integrates all daily activity...
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Related ArticlesCleidocranial Dysplasia: Management of the Multiple Craniofacial and Skeletal Anomalies. J Craniofac Surg. 2020 Mar 27;: Authors: Jirapinyo C, Deraje V, Huang G, Gue S, Anderson PJ, Moore MH Abstract Cleidocranial dysplasia (CCD) is a rare autosomal dominant disorder caused by mutations in the Runx2 gene. The CCD is characterized by frontal bossing, a patent anterior fontanelle, presence of Wormian bones, midface hypoplasia, multiple...
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Related ArticlesSurviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19). Crit Care Med. 2020 Mar 27;: Authors: Alhazzani W, Møller MH, Arabi YM, Loeb M, Gong MN, Fan E, Oczkowski S, Levy MM, Derde L, Dzierba A, Du B, Aboodi M, Wunsch H, Cecconi M, Koh Y, Chertow DS, Maitland K, Alshamsi F, Belley-Cote E, Greco M, Laundy M, Morgan JS, Kesecioglu J, McGeer A, Mermel L, Mammen MJ, Alexander PE, Arrington A,...
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Related ArticlesEffect of Lifestyle Factors on Outcomes in Patients With Inflammatory Bowel Diseases. Am J Gastroenterol. 2020 Mar 30;: Authors: Rozich JJ, Holmer A, Singh S Abstract Various lifestyle factors including physical activity and obesity, stress, sleep, and smoking may modify the risk of developing inflammatory bowel diseases (IBDs). In patients with established IBD, these lifestyle factors may significantly impact the natural history and...
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Related ArticlesMulti-dimensional role of the parabrachial nucleus in regulating pain-related affective disturbances in trigeminal neuropathic pain. J Oral Sci. 2020;62(2):160-164 Authors: Katagiri A, Kato T Abstract Neuropathic pain is characterized by sensory abnormalities, such as mechanical allodynia and heat hyperalgesia, associated with alteration in the peripheral and central nervous systems. After trigeminal nerve injury, phenotypic changes that...
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Related ArticlesIron deficiency and sleep - A scoping review. Sleep Med Rev. 2020 Feb 08;51:101274 Authors: Leung W, Singh I, McWilliams S, Stockler S, Ipsiroglu OS Abstract Iron deficiency (ID) is associated with sleep disorders, but standardized assessment of iron status in the diagnostic work-up and iron supplementation as treatment have not been considered in clinical practice. We investigated associations of ID with type and severity of sleep disorders...
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Related ArticlesFrom seeds to plasma: Confirmed exposure of multiple farmland bird species to clothianidin during sowing of winter cereals. Sci Total Environ. 2020 Mar 19;723:138056 Authors: Lennon RJ, Peach WJ, Dunn JC, Shore RF, Pereira MG, Sleep D, Dodd S, Wheatley CJ, Arnold KE, Brown CD Abstract Neonicotinoids are the largest group of systemic insecticides worldwide and are most commonly applied as agricultural seed treatments. However, little is...
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Related ArticlesSleep disturbance as a predictor of anxiety in children with Fetal Alcohol Spectrum Disorders and typically developing children. Res Dev Disabil. 2020 Mar 27;101:103610 Authors: Mughal R, Joyce A, Hill C, Dimitriou D Abstract BACKGROUND: High levels of anxiety and sleep problems are common features of Fetal Alcohol Spectrum Disorders (FASD). The strong association between sleep and anxiety has been documented in typically developing (TD)...
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Related ArticlesComplementary therapy with traditional Chinese medicine for a patient with Sjögren's syndrome: A case report. Explore (NY). 2020 Mar 17;: Authors: Wang W, Wang X, Fan Y Abstract OBJECTIVE: . A case study was used to discuss the effects of traditional Chinese medicine (TCM) treatments on Sjögren's syndrome. CLINICAL FEATURES AND OUTCOMES: . A 45-year-old woman suffered from dry eyes, dry mouth, and fatigue for six months and was diagnosed...
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Related ArticlesObstructive sleep apnoea and cardiovascular consequences: Pathophysiological mechanisms. Arch Cardiovasc Dis. 2020 Mar 26;: Authors: Arnaud C, Bochaton T, Pépin JL, Belaidi E Abstract Obstructive sleep apnoea syndrome is a growing health concern, affecting nearly one billion people worldwide; it is an independent cardiovascular risk factor, associated with incident obesity, insulin resistance, hypertension, arrhythmias, stroke, coronary...
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Related ArticlesOral Appliances for Snoring and Obstructive Sleep Apnea. Otolaryngol Clin North Am. 2020 Mar 26;: Authors: Mickelson SA Abstract Obstructive sleep apnea is a common condition, caused primarily by narrowing of the nasal and pharyngeal airway, leading to partial or complete airway collapse during sleep. Treatment with positive airway pressure (PAP) is considered first-line therapy, due to an efficacy rate of approximately 95%, yet long-term...
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Related ArticlesThe relationship between shift-work, sleep, and mental health among paramedics in Australia. Sleep Health. 2020 Mar 26;: Authors: Khan WAA, Conduit R, Kennedy GA, Jackson ML Abstract OBJECTIVES: This study aimed to investigate the prevalence of sleep and mental health issues, the role of chronotype, and the relationship between these variables in Australian paramedics. DESIGN: A cross-sectional study. SETTINGS: Cross-sectional...
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Related ArticlesSocial, emotional, and behavioral problems and parent-reported sleep bruxism in schoolchildren. J Am Dent Assoc. 2020 Mar 26;: Authors: Brancher LC, Cademartori MG, Jansen K, da Silva RA, Bach S, Reyes A, Boscatto N, Goettems ML Abstract BACKGROUND: A number of theories associate emotional factors with the triggering of sleep bruxism (SB). Few studies have used validated instruments to assess psychological characteristics and SB in children....
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Related ArticlesHow Much is Too Much After All? Primary Snoring as a Remaining Unsolved Issue. J Clin Sleep Med. 2020 Mar 30;: Authors: Meira E Cruz M, Soca R, Kryger M PMID: 32223883 [PubMed - as supplied by publisher]
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Related ArticlesSubclinical impairment of dynamic left ventricular systolic and diastolic function in patients with obstructive sleep apnea and preserved left ventricular ejection fraction. BMC Pulm Med. 2020 Mar 29;20(1):76 Authors: D'Andrea A, Canora A, Sperlongano S, Galati D, Zanotta S, Polistina GE, Nicoletta C, Ghinassi G, Galderisi M, Zamparelli AS, Lancellotti P, Bocchino M Abstract BACKGROUND: Hypoxia affects myocardial oxygen supply resulting...
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Related ArticlesThe Humanistic and Economic Burden of Pediatric Focal Seizures in the United States. J Child Neurol. 2020 Mar 30;:883073820911785 Authors: Gibbs SN, Choi J, Khilfeh I, Ahmed KH, Yermilov I, Segal E Abstract OBJECTIVE: To better understand the humanistic and economic burden of focal seizures in children 2-12 years old. METHODS: We conducted a targeted literature review by searching MEDLINE for English-language publications reporting...
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Related ArticlesProspective Qualitative Multidimensional Assessment of the Postoperative Rhinoplasty Experience. Facial Plast Surg Aesthet Med. 2020 Mar 30;: Authors: Gadkaree SK, Shaye DA, McCarty JC, Occhiogrosso J, Spagnuolo G, Derakhshan A, Lee LN Abstract Background: Understanding the multidimensional postoperative patient experience after rhinoplasty is critical for preoperative counseling and postoperative management. Methods: A prospective clinical...
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Related ArticlesExploring New Use of Cannabis among Older Adults. Clin Gerontol. 2020 Mar 29;:1-7 Authors: Baumbusch J, Sloan Yip I Abstract Objectives: In Canada, cannabis prohibition ended in October 2018. Older adults are the fastest growing group of cannabis users and are out-pacing other groups as new users. Clinical evidence indicates that cannabis may be helpful for select medicinal purposes in this population. Yet there is limited research about...
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Related ArticlesBeliefs about sleep paralysis in Turkey: Karabasan attack. Transcult Psychiatry. 2020 Mar 29;:1363461520909616 Authors: Jalal B, Sevde Eskici H, Acarturk C, Hinton DE Abstract The present study examined explanations of sleep paralysis (SP) in Turkey. The participants were 59 college students recruited in İstanbul, Turkey, who had experienced SP at least once in their lifetime. Participants were administered the Sleep Paralysis Experiences...
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Related ArticlesIntracranial Epidural Abscess in a 9-Year-Old Boy With Precocious Puberty and Use of Continuous Positive Airway Pressure. J Child Neurol. 2020 Mar 30;:883073820912047 Authors: Edlund W, Patel N, DeLone D, Kotagal S Abstract Intracranial extension of rhinosinusitis is rare in children. We report a 9-year-old immunocompetent boy with central precocious puberty and obstructive sleep apnea-hypopnea syndrome who developed an intracranial epidural...
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