Κυριακή 5 Απριλίου 2020


The glucocorticoids prednisone and dexamethasone differentially modulate T cell function in response to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade
Abstract On-treatment steroids for countering immune checkpoint inhibitor-induced inflammatory responses (irAEs) are a hallmark of cancer immunotherapy. However, the suppressive nature of steroids has raised questions regarding their ability to compromise the function of the ‘proliferative burst’ of effector T cells induced by immune checkpoint antibodies. We investigated the effector functions and the co-inhibitory receptor profile of stimulated peripheral blood mononuclear cells...
Cancer Immunology, Immunotherapy
Fri Apr 03, 2020 03:00
Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog.
Related ArticlesCortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog. Cell Rep. 2020 Mar 31;30(13):4490-4504.e4 Authors: Zhang Y, Liu G, Guo T, Liang XG, Du H, Yang L, Bhaduri A, Li X, Xu Z, Zhang Z, Li Z, He M, Tsyporin J, Kriegstein AR, Rubenstein JL, Yang Z, Chen B Abstract Neural stem cells (NSCs) in the prenatal neocortex progressively generate different subtypes of glutamatergic projection neurons....
pubmed: frontiers neuroscien...
Fri Apr 03, 2020 13:02
Trismus and oral haematoma, a rare presentation of tetanus
Publication date: March–April 2020Source: Acta Otorrinolaringologica (English Edition), Volume 71, Issue 2Author(s): Miguel Mayo-Yáñez, Liliana Invencio-Da Costa
Acta Otorrinolaringologica English
Fri Apr 03, 2020 12:51
The Levator Claviculae Muscle
Publication date: March–April 2020Source: Acta Otorrinolaringologica (English Edition), Volume 71, Issue 2Author(s): José Miguel Costa González, Rosa Delia Ramírez Ruíz, Anna Sumarroca Trouboul
Acta Otorrinolaringologica English
Fri Apr 03, 2020 12:51
Parathyroid Carcinoma, An Unusual Cause of Primary Hyperparathyroidism
Publication date: March–April 2020Source: Acta Otorrinolaringologica (English Edition), Volume 71, Issue 2Author(s): Liliana Filipa Invêncio da Costa, Fabian Alzate Amaya, Jesús Herranz González Botas
Acta Otorrinolaringologica English
Fri Apr 03, 2020 12:51
Laryngeal Cleft: Diagnosis and Treatment of an Unusual Presentation in an Adult
Publication date: March–April 2020Source: Acta Otorrinolaringologica (English Edition), Volume 71, Issue 2Author(s): Isabel Garcia-Lopez, Carmen Aranzazu Perez-Fernandez, Pilar Garcia-Raya, Javier Gavilan
Acta Otorrinolaringologica English
Fri Apr 03, 2020 12:51
Silicone Injection Complication in Facial Aesthetics: Migration to Adenoids
Publication date: March–April 2020Source: Acta Otorrinolaringologica (English Edition), Volume 71, Issue 2Author(s): F. Javier García Callejo
Acta Otorrinolaringologica English
Fri Apr 03, 2020 12:51
Facial Paralysis: Clinical Practice Guideline of the Spanish Society of Otolaryngology
Publication date: March–April 2020Source: Acta Otorrinolaringologica (English Edition), Volume 71, Issue 2Author(s): Luis Lassaletta, José Manuel Morales-Puebla, Xabier Altuna, Álvaro Arbizu, Miguel Arístegui, Ángel Batuecas, Carlos Cenjor, Juan Manuel Espinosa-Sánchez, Leire García-Iza, Pilar García-Raya, Teresa González-Otero, Manuel Mañós, Carlos Martín, Susana Moraleda, Jose María Roda, Susana Santiago, Jesús Benítez, Laura Cavallé, Victor Correia, Jose Manuel Estévez
Acta Otorrinolaringologica English
Fri Apr 03, 2020 12:51
Cold Knife Dissection and Bipolar Diathermy Vs Harmonic Scalpel in Parotid Gland Surgery for Benign Tumours
Publication date: March–April 2020Source: Acta Otorrinolaringologica (English Edition), Volume 71, Issue 2Author(s): Carlos Miguel Chiesa-Estomba, Ekhiñe Larruscain-Sarasola, Jose Angel González-García, Jon Alexander Sistiaga-Suarez, Xabier Altuna-Mariezcurrena
Acta Otorrinolaringologica English
Fri Apr 03, 2020 12:51
Butterfly tragal cartilage for repair of focal canal wall defects
Publication date: March–April 2020Source: Acta Otorrinolaringologica (English Edition), Volume 71, Issue 2Author(s): Kartik Parelkar, Devika Shere, Keya Shah
Acta Otorrinolaringologica English
Fri Apr 03, 2020 12:51
Endoscopic type 3 tympanoplasty: Functional outcomes in chronic otitis media
Publication date: March–April 2020Source: Acta Otorrinolaringologica (English Edition), Volume 71, Issue 2Author(s): Ricardo Bartel, Francesc Cruellas, Miriam Hamdan, Felipe Benjumea, Gabriel Huguet, Xavier Gonzalez-Compta, Enric Cisa, Manel Manos
Acta Otorrinolaringologica English
Fri Apr 03, 2020 12:51
Incidence of Diffuse Idiopathic Skeletal Hyperostosis From a Model of Dysphagia
Publication date: March–April 2020Source: Acta Otorrinolaringologica (English Edition), Volume 71, Issue 2Author(s): Francisco Javier García Callejo, Natsuki Oishi, Isabel López Sánchez, Beatriz Pallarés Martí, Andrea Rubio Fernández, María José Gómez Gómez
Acta Otorrinolaringologica English
Fri Apr 03, 2020 12:51
Oncological Results of Salvage Laryngectomy in Patients With Laryngeal Carcinoma
Publication date: March–April 2020Source: Acta Otorrinolaringologica (English Edition), Volume 71, Issue 2Author(s): Xavier León, Victoria Montoro, Carlota Rovira, Eduard Neumann, Montserrat López, Jacinto García, Miquel Quer
Acta Otorrinolaringologica English
Fri Apr 03, 2020 12:51
Modified inspiratory muscle training (m-IMT) as promising treatment for gastro-oesophageal reflux disease (GERD)
Publication date: March–April 2020Source: Acta Otorrinolaringologica (English Edition), Volume 71, Issue 2Author(s): Antonio Moffa, Giuseppe Oliveto, Francesco Di Matteo, Peter Baptista, Alicia Cárdenas, Michele Cassano, Manuele Casale
Acta Otorrinolaringologica English
Fri Apr 03, 2020 12:51

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