Cancers,

Cancers, Vol. 12, Pages 1157: Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib

Cancers, Vol. 12, Pages 1157: Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib Cancers doi: 10.3390/cancers12051157 Authors: Changhong Ke Huan Hou Jiayu Li Kui Su Chaohong Huang Yue Lin Zhiqiang Lu Zhiyun Du Wen Tan Zhengqiang Yuan Tumour necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) is a promising anti-cancer agent that rapidly induces apoptosis in cancer...

Cancers

17h

Cancers, Vol. 12, Pages 1156: Impact and Diagnostic Gaps of Comprehensive Genomic Profiling in Real-World Clinical Practice

Cancers, Vol. 12, Pages 1156: Impact and Diagnostic Gaps of Comprehensive Genomic Profiling in Real-World Clinical Practice Cancers doi: 10.3390/cancers12051156 Authors: Aditi P. Singh Elaine Shum Lakshmi Rajdev Haiying Cheng Sanjay Goel Roman Perez-Soler Balazs Halmos Purpose: next-generation sequencing based comprehensive genomic profiling (CGP) is becoming common practice. Although numerous studies have shown its feasibility to identify actionable genomic...

Cancers

17h

Cancers, Vol. 12, Pages 1155: MHC Class I Regulation: The Origin Perspective

Cancers, Vol. 12, Pages 1155: MHC Class I Regulation: The Origin Perspective Cancers doi: 10.3390/cancers12051155 Authors: Alicja Sznarkowska Sara Mikac Magdalena Pilch Viral-derived elements and non-coding RNAs that build up “junk DNA” allow for flexible and context-dependent gene expression. They are extremely dense in the MHC region, accounting for flexible expression of the MHC I, II, and III genes and adjusting the level of immune response to the...

Cancers

17h

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