Δευτέρα 4 Μαΐου 2020


On the Ground State to Hamiltonian Elliptic System with Choquard’s Nonlinear Term
In the present paper, we consider the following Hamiltonian elliptic system with Choquard’s nonlinear term where is a bounded domain with a smooth boundary, ,, and is the primitive of , similarly for . By establishing a strongly indefinite variational setting, we prove that the above problem has a ground state solution.
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1m
Numerical Simulation during Short-Shot Water-Assisted Injection Molding Based on the Overflow Cavity for Short-Glass Fiber-Reinforced Polypropylene
Compared with water penetration condition of short-shot water-assisted injection molding with or without overflow cavity, it can be known from theory and common knowledge that short-shot water-assisted injection molding with overflow cavity has many advantages, such as it can save materials and energy. Then, the effects of melt short shot size, water injection delay time, melt temperature and water injection pressure on the penetration of water after penetration, and the orientation distribution...
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1m
Interactive Algorithms in Complex Image Processing Systems Based on Big Data
In the era of big data, images and videos are one of the main means of information dissemination. In recent years, research on the problem of image and video reorganization and integration has become a hot topic in digital image processing technology. Using a computer for image processing, complicated programming is unavoidable. Therefore, it is necessary to optimize the interactive algorithms for image processing. In this paper, the content of image processing experiment is screened and integrated,...
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1m
The Threat of Antibiotics and Heavy Metal Pollution to Human Health and Potential Solutions
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Circumferential Expansion Property of Composite Wrapping System for Main Cable Protection of Suspension Bridge
A composite wrapping system for main cable protection of suspension bridges was designed by using prepreg fiber-reinforced composites and nitrile rubber. The circumferential expansion performance of the system was tested, and the curves of circumferential bearing capacity and radial displacement of the components were obtained. Failure modes of each group of components were compared and analyzed. The results show that most of the components are vertically fractured at the lap transition. The increase...
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1m
The Analysis on Seepage Field of Grouted and Shotcrete Lined Underwater Tunnel
Groundwater control in underwater tunnels by drilling and blasting method is generally carried out by grouting ring, shotcrete lining (primary lining), and concrete lining. The permeable grouting ring and shotcrete lining have an important impact on seepage field. However, the currently published research models of related results are for homogeneous and isotropic single-layer unlined tunnels, ignoring the important effects of tunnel grouting circles and primary lining. If the conclusions of the...
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1m
Microcluster-Based Incremental Ensemble Learning for Noisy, Nonstationary Data Streams
Data stream classification becomes a promising prediction work with relevance to many practical environments. However, under the environment of concept drift and noise, the research of data stream classification faces lots of challenges. Hence, a new incremental ensemble model is presented for classifying nonstationary data streams with noise. Our approach integrates three strategies: incremental learning to monitor and adapt to concept drift; ensemble learning to improve model stability; and a microclustering...
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1m
A Novel Radial Basis Neural Network-Leveraged Fast Training Method for Identifying Organs in MR Images
We propose a new method for fast organ classification and segmentation of abdominal magnetic resonance (MR) images. Magnetic resonance imaging (MRI) is a new type of high-tech imaging examination fashion in recent years. Recognition of specific target areas (organs) based on MR images is one of the key issues in computer-aided diagnosis of medical images. Artificial neural network technology has made significant progress in image processing based on the multimodal MR attributes of each pixel in MR...
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1m
Neuromuscular, Perceptual, and Temporal Determinants of Movement Patterns in Wheelchair Fencing: Preliminary Study
The objective of the present study was to determine the structure of the movement pattern performed during a wheelchair fencing lunge that is executed in response to visual and sensory stimuli. In addition, a comparison was made between fencers in the categories A and B of disability. In addition, the analysis involved the correlation between the duration of the sensorimotor response and the value of the bioelectric signal recorded in selected muscles. Seven Paralympic team athletes specializing...
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1m
The Mechanism of Zinc Sulfate in Improving Fertility in Obese Rats Analyzed by Sperm Proteomic Analysis
This study investigates the mechanism underlying the improving effect of zinc on fertility in obese rats using proteomics. The effects of three different doses of ZnSO4 on spermatogenesis and hormone levels were studied. Testicular spermatogenesis was observed by HE staining. Serum estrogen and testosterone levels were measured by chemiluminescent microparticle immunoassay. Sperm proteomic analysis was performed by liquid chromatography-mass spectrometry. The DAVID database was used to perform the...
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1m
Systematic Analysis of Environmental Chemicals That Dysregulate Critical Period Plasticity-Related Gene Expression Reveals Common Pathways That Mimic Immune Response to Pathogen
The tens of thousands of industrial and synthetic chemicals released into the environment have an unknown but potentially significant capacity to interfere with neurodevelopment. Consequently, there is an urgent need for systematic approaches that can identify disruptive chemicals. Little is known about the impact of environmental chemicals on critical periods of developmental neuroplasticity, in large part, due to the challenge of screening thousands of chemicals. Using an integrative bioinformatics...
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1m
Assessment of Levels of Natural Radioactivity in Sand Samples Collected from Ekalakala in Machakos County, Kenya
Construction sand is naturally polluted with radionuclides of terrestrial origin. In this study, specific activities of 238U, 232Th, and 40K in 30 sand samples collected along the Ekalakala River, Machakos County, Kenya, were measured using a high-purity germanium γ-ray spectrometer. The specific activities ranged between 9.7 Bqkg−1 and 24.0 Bqkg−1, 11.5 Bqkg−1 and 26.2 Bqkg−1, and 820 Bqkg−1 and 1850 Bqkg−1 for 238U, 232Th, and 40K, respectively. While the mean specific activities for 238U and 232Th...
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1m
Association of IL-1β, IL-6, TNF-α, and TGFβ1 Gene Polymorphisms with Recurrent Spontaneous Abortion in Polycystic Ovary Syndrome
Recurrent spontaneous abortion (RSA) is a common pregnancy-associated complication of polycystic ovary syndrome (PCOS) which is an endocrine malfunction disease. Patients with PCOS may have several underlying contributing and interrelated factors, which have been reported in women with RSA. The incidence rate between PCOS and RSA remains uncertain. The aim of this study is to determine the possible association of IL-1β-511C/T, IL-6-174G/C, TNF-α-1031T/C, and TGFβ1-509T/C with RSA patients with or...
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1m
DNA Vaccine Treatment in Dogs Experimentally Infected with Trypanosoma cruzi
Chagas disease is a chronic and potentially lethal disorder caused by the parasite Trypanosoma cruzi, and an effective treatment has not been developed for chronic Chagas disease. The objective of this study was to determine the effectiveness of a therapeutic DNA vaccine containing T. cruzi genes in dogs with experimentally induced Chagas disease through clinical, pathological, and immunological analyses. Infection of Beagle dogs with the H8 T. cruzi strain was performed intraperitoneally with 3500...
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1m
An Efficient Integrity Verification and Authentication Scheme over the Remote Data in the Public Clouds for Mobile Users
The digitalization of the modern world and its applications seem to be integrated more with the mobile phones than with any other communication devices. Since the mobile phones have become ubiquitous with applications for nearly all users, they have become a preferred choice for uploading the sensitive information to the cloud servers. Though the drive for data storage in cloud servers is implicit due to its pay-per-use policies, the manipulation of the data present in the cloud servers by hackers...
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1m
Septin 9 Methylation in Nasopharyngeal Swabs: A Potential Minimally Invasive Biomarker for the Early Detection of Nasopharyngeal Carcinoma
Nasopharyngeal carcinoma (NPC) is highly prevalent in Southeast Asia, and an unfavorable outcome is usually attributed to advanced stage NPC. Current methods for the early diagnosis of NPC have limitations in clinical practice. The aim of this study was to investigate the diagnostic ability of Septin 9 methylation for NPC. A quantitative methylation-sensitive PCR (qMS-PCR) assay was developed to measure the methylation status and levels of Septin 9 in nasopharyngeal tissues and paired swabs from...
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1m
Preoperative Steroid Use in Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment after 23-Gauge Vitrectomy
Background. Rhegmatogenous retinal detachment associated with choroidal detachment (RRDCD) is rare and the prognosis is poor. This retrospective study evaluated the effect of preoperative steroid on the clinical outcome of patients with RRDCD receiving 23-gauge pars plana vitrectomy (PPV). Methods. Sixty-six patients (67 eyes) with diagnosed RRDCD underwent 23-gauge PPV. The patients assigned to receive systemic or subtenon injection of preoperative steroids were considered Group A (35 eyes) and...
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1m
Efficacy of Neoadjuvant Chemotherapy with Epirubicin and Cyclophosphamide and Weekly Paclitaxel and Trastuzumab in Human Epidermal Growth Factor Receptor 2–Positive Breast Carcinoma: A Real-World Study
Background. Trastuzumab has been introduced a decade ago and demonstrated improvement in the prognosis in patients with human epidermal growth factor receptor 2- (HER2-) positive (+) breast carcinoma (BC). This study is aimed at evaluating the efficacy of epirubicin/cyclophosphamide with weekly paclitaxel-trastuzumab as neoadjuvant chemotherapies in HER2+ BC patients. Methods. A total of 234 HER2+ BC patients were given neoadjuvant chemotherapy (NAC) between 2010 and 2016. The primary endpoints were...
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1m
Under-Five Mortality in Buea Health District, Southwest Cameroon: Evidence from a Community-Based Birth Cohort Study of Rate, Causes, and Age-Specific Patterns
Background. Updating the knowledge base on the causes and patterns of under-five mortality (U5M) is crucial for the design of suitable interventions to improve survival of children under five. Objectives. To assess the rate, causes, and age-specific patterns of U5M in Buea Health District, Cameroon. Methods. A retrospective cohort study involving 2000 randomly selected households was conducted. Live births registered between September 2004 and September 2009 were recorded. The under-five mortality...
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1m
Fusion of FDG-PET Image and Clinical Features for Prediction of Lung Metastasis in Soft Tissue Sarcomas
Extracting massive features from images to quantify tumors provides a new insight to solve the problem that tumor heterogeneity is difficult to assess quantitatively. However, quantification of tumors by single-mode methods often has defects such as difficulty in features extraction and high computational complexity. The multimodal approach has shown effective application prospects in solving these problems. In this paper, we propose a feature fusion method based on positron emission tomography (PET)...
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1m
Distribution and Prognostic Significance of Estrogen Receptor α (ERα), Estrogen Receptor β (ERβ), and Human Epidermal Growth Factor Receptor 2 (HER-2) in Thyroid Carcinoma
Purpose. The primary aim of this study was to determine the incidence of estrogen receptor α (ERα), estrogen receptor β (ERβ), and human epidermal growth factor receptor 2 (HER-2) expression in various subtypes of thyroid carcinoma (TC) of follicular origin and the secondary aim was to correlate the expression with various clinicopathologic prognostic factors. Methods. Immunohistochemistry analysis was performed on archival paraffin-embedded tissue sections (1991–2016). ERα, ERβ, and HER-2 expressions...
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1m
Mouse Umbilical Cord Mesenchymal Stem Cell Paracrine Alleviates Renal Fibrosis in Diabetic Nephropathy by Reducing Myofibroblast Transdifferentiation and Cell Proliferation and Upregulating MMPs in Mesangial Cells
Transplantation of umbilical cord mesenchymal stem cells (UC-MSCs) is currently considered a novel therapeutic strategy for diabetic nephropathy (DN). However, the mechanisms by which UC-MSCs ameliorate renal fibrosis in DN are not well understood. Herein, we firstly investigated the therapeutic effects of mouse UC-MSC infusion on kidney structural and functional impairment in streptozotocin- (STZ-) induced diabetic mice. We found that the repeated injection with mUC-MSCs alleviates albuminuria,...
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1m
Serum Levels of Matrix Metalloproteinase-1 in Brazilian Patients with Benign Prostatic Hyperplasia or Prostate Cancer
Metalloproteinases (MMPs) are involved in metastatic tumor processes, with changes in circulating levels detected in several cancer types. Here, we compare serum concentrations of metalloproteinase-1 (MMP-1) across individuals clinically diagnosed with prostate cancer (PCa) or benign prostatic hyperplasia (BPH), correcting results for the rs495366 single nucleotide polymorphism (SNP) that predisposes to differential MMP-1 levels. 196 men aged ≥50 years were followed at a university hospital urology...
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1m
Risk Factors Associated with Fatal Dengue Hemorrhagic Fever in Adults: A Case Control Study
Background. Dengue is endemic in most parts of the tropics with a significant mortality of 1–5%. Although individual case reports and case series have been published, large-scale case controls studies are few. The objective of this study was to find clinical and laboratory predictors of mortality in dengue. Methods. Hospital case record based case control study was performed. Results. Twenty fatalities with 80 controls were analyzed. Clinical parameters of postural dizziness (OR 3.2; 95% CI 1.1–8.9),...
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1m
Anti-Inflammatory and Analgesic Effect of Arachic Acid Ethyl Ester Isolated from Propolis
Inflammatory diseases are a real public health problem worldwide. Many synthetic drugs used in the treatment of inflammatory diseases such as steroidal anti-inflammatory drugs, nonsteroidal anti-inflammatory drugs (NSAIDs) and immunosuppressive drugs have harmful side effects. However, there are natural products like propolis, which is traditionally used in the treatment of pain. The objective of this work was to evaluate the anti-inflammatory and analgesic activities of the ethyl ester of arachic...
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1m
Dracocephalum moldavica L. Extracts Protect H9c2 Cardiomyocytes against H2O2-Induced Apoptosis and Oxidative Stress
Background and Objectives. Dracocephalum moldavica L. is an herbal medicine used to treat cardiovascular diseases in China. The purpose of this study was to assess the cardioprotective effect of D. moldavica L. extracts against H2O2-induced apoptosis and oxidative stress in H9c2 cells and to explore the mechanism behind this effect. Materials and Methods. The petroleum ether (petrol), dichloromethane (CH2Cl2), ethyl acetate (EtOAc), and n-butyl alcohol (n-BuOH) fractions were isolated from alcohol...
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1m
Immunologic and Clinical Failure of Antiretroviral Therapy in People Living with Human Immunodeficiency Virus within Two Years of Treatment
Background. Early initiation of highly active antiretroviral therapy (HAART) decreases human immunodeficiency virus- (HIV-) related complications, restores patients’ immunity, decreases viral load, and substantially improves quality of life. However, antiretroviral treatment failure considerably impedes the merits of HAART. Objective. This study is aimed at determining the prevalence of immunologic and clinical antiretroviral treatment failure. Methods. A cross-sectional study design using clinical...
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1m
Effect of Hydrocortisone on Intradialytic Hypotension: A Preliminary Investigational Study
Introduction. Approximately 15 to 33% of all dialysis treatments are complicated by intradialytic hypotension (IDH). In this study, we tested the hypothesis that the intravenous administration of hydrocortisone prior to HD treatment could prevent IDH or at least decrease the drop in the blood pressure resulting from IDH. Methods. This study was approved by our local ethics committee/IRB (2017/87) and by the Jordan Food and Drug Administration (7/clinical/18). Additionally, it is registered on ClinicalTrials.gov...
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1m
Histopathology of Cutaneous Leishmaniasis Caused by Leishmania donovani in Sri Lanka
Cutaneous leishmaniasis (CL) is a neglected tropical disease that is gaining importance in Sri Lanka and internationally. The clinical presentation, pathology, and method of parasite elimination in CL vary according to the species. Leishmania donovani is the causative organism for leishmaniasis in Sri Lanka. This collaborative cross-sectional study describes the clinicopathological features of cutaneous leishmaniasis among personnel of the tri-forces serving in the North and East of the country....
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1m
The Impact of Intraoperative Hypothermia on Blood Loss and Allogenic Blood Transfusion in Total Knee and Hip Arthroplasty: A Retrospective Study
Background. Total joint arthroplasty (TJA) usually leads to substantial blood loss, which may cause allogenic blood transfusion. Hypothermia occurring during operation has been reported to increase blood loss and transfusion rates in nonorthopedic cohorts. However, the relationship between intraoperative hypothermia and blood loss remains controversial in patients undergoing orthopedic surgeries. The aims of this study were to investigate the incidence of hypothermia and identify the impact of intraoperative...
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1m
Analysis of Lumbar Sagittal Curvature in Spinal Decompression and Fusion for Lumbar Spinal Stenosis Patients under Roussouly Classification
To evaluate the clinical significance of spinal decompression and fusion for lumbar spinal stenosis in old patients under Roussouly classification, 160 old patients (>60 year old) with lumbar spinal stenosis underwent spinal decompression, and fusion were retrospectively studied. According to Roussouly classification, patients were divided into 4 groups, in which Roussouly types I, II, and IV were the nonstandard group and Roussouly type III was the standard group. Visual analog scale (waist,...
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1m
The Effect of Different Treatment Regimens and Multiple Risk Factors on Adverse Pregnancy Outcomes among Syphilis-Seropositive Women in Guangzhou: A Retrospective Cohort Study
Background. To eliminate mother-to-child transmission of syphilis, the Chinese government recommends a treatment regimen that slightly differs from the World Health Organization- (WHO-) recommended treatment. However, little is known about their difference in efficacy. This study is aimed at comparing the effect of China-recommended and WHO-recommend treatment regimens on adverse pregnancy outcomes (APOs) and at examining associated risk factors of APOs among syphilis-seropositive women. Methods....
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1m
Gene Coexpression Network and Module Analysis across 52 Human Tissues
Gene coexpression analysis is widely used to infer gene modules associated with diseases and other clinical traits. However, a systematic view and comparison of gene coexpression networks and modules across a cohort of tissues are more or less ignored. In this study, we first construct gene coexpression networks and modules of 52 GTEx tissues and cell lines. The network modules are enriched in many tissue-common functions like organelle membrane and tissue-specific functions. We then study the correlation...
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1m
A Centralized Outbreak of Varicella among Children Attending Preschool in Suzhou, China
Background. Varicella vaccine is available for voluntary purchase with a single dose currently recommended for children aged ≥12 months. An epidemiological study was undertaken in order to determine the characteristics of the outbreak, assess vaccine effectiveness, and examine risk factors for vaccine failure. Methods. A varicella case was defined as a generalized papulovesicular rash (without other apparent causes) in a child without prior varicella attending the kindergarten during February 22...
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1m
Autophagy Suppresses Toll-Like Receptor 3-Mediated Inflammatory Reaction in Human Epidermal Keratinocytes
Autophagy, one mechanism of programmed cell death, is fundamental to cellular homeostasis. Previous studies have identified autophagy as a novel mechanism by which cytokines control the immune response. However, its precise role in immune-related inflammatory skin diseases such as psoriasis remains unclear. Thus, this study explored the functional role of autophagy in psoriatic inflammation of epidermal keratinocytes. Strong light chain 3 immunoreactivity was observed in epidermal keratinocytes of...
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1m
The Cataleptic, Asymmetric, Analgesic, and Brain Biochemical Effects of Parkinson’s Disease Can Be Affected by Toxoplasma gondii Infection
Purpose. Parkinson’s disease (PD) is a neurodegenerative disorder with progressive motor defects. Therefore, the aim of the present investigation was to examine whether catalepsy, asymmetry, and nociceptive behaviors; the Nissl-body and neuron distribution; brain-derived neurotrophic factor (BDNF); malondialdehyde (MDA); total antioxidant capacity (TAC) levels; and the percentage of dopamine depletion of striatal neurons in the rat model of Parkinson’s disease (PD) can be affected by Toxoplasma gondii...
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1m
Intracranial Infections in Neurological Surgery: The Changes of Circular RNA Expression and Their Possible Function Mechanism
Background and Objective. Circular RNA (circRNA) often has high stability and has been widely studied as diagnostic markers in many diseases, including neurodegenerative disorders, diabetes, and various types of cancers. In this study, circRNA was evaluated as a diagnostic marker for central nervous system infection in neurological surgery. Methods. circRNA expression was analysed in six cerebrospinal fluid (CSF) samples from three patients of the infectious and noninfectious phases using an Arraystar...
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1m
Activation of the Nrf2/HO-1 Pathway by Amomum villosum Extract Suppresses LPS-Induced Oxidative Stress In Vitro and Ex Vivo
Despite its deleterious effects on living cells, oxidative stress plays essential roles in normal physiological processes and provides signaling molecules for cell growth, differentiation, and inflammation. Macrophages are equipped with antioxidant mechanisms to cope with intracellular ROS produced during immune response, and Nrf2 (NF-E2-related factor 2)/HO-1 (heme oxygenase-1) pathway is an attractive target due to its protective effect against ROS-induced cell damage in inflamed macrophages. We...
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1m
Advanced Ultrasound Screening for Temporomandibular Joint (TMJ) Internal Derangement
Purpose. To present an advanced ultrasound (US) technique and propose its use as a screening diagnostic tool for temporomandibular joint (TMJ) internal derangement. Materials and Methods. The technique is based on maintaining the US probe parallel to the articular disc, rather than traditional axial and coronal views, with the position described relative to a clock face. Validation was achieved by direct comparison with magnetic resonance imaging (MRI). A total of 61 patients, with age ranging from...
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1m

Effect of Denosumab on Bone Mineral Density of Hematopoietic Stem Cell Transplantation Recipients
Purpose. Denosumab is a monoclonal antibody that prevents the development of osteoclasts. The effect of denosumab in solid organ transplant recipients has been elucidated, but its effect in haematopoietic stem cell transplantation recipients has not been studied yet. The aim of this study was to determine the effectiveness and safety of denosumab in haematopoietic stem cell transplantation recipients. Methods. We retrospectively evaluated 33 female patients with osteoporosis (mean age 52.6 ± 9.8...
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1m
Rapid Convergence of Approximate Solutions for Fractional Differential Equations
In this paper, we develop a generalized quasilinearization technique for a class of Caputo’s fractional differential equations when the forcing function is the sum of hyperconvex and hyperconcave functions of order (), and we obtain the convergence of the sequences of approximate solutions by establishing the convergence of order ().
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12h
Field Equations and Lagrangian of the Kaluza Energy-Momentum Tensor
We provide an analysis and statement of the source term in the classical Kaluza field equations, by considering the 5-dimensional (5D) energy-momentum tensor corresponding to the 5D geodesic hypothesis that is typically presumed in the Kaluza theory. By providing the 5D matter Lagrangian, this work completes a Lagrangian analysis of the classical Kaluza theory that began by establishing the proper form of the unique Kaluza field Lagrangian. This work considers the transformation properties necessitated...
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12h
Impact of Jiggling Exercise as Conservative Treatment for Hip Osteoarthritis: A Report of Two Cases
Total hip arthroplasty has been recognized as a feasible treatment for hip osteoarthritis, especially in advanced and terminal stages, but whether it is the best treatment for patients who are younger, have comorbidities, and/or are likely to have low compliance to medical treatment is unknown. Jiggling exercise, which involves the continuous shaking of the foot and leg in small steps, has been reported to be the easiest and a less invasive exercise for patients with hip osteoarthritis. We herein...
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12h
Nuclear-Targeting Delivery of CRISPRa System for Upregulation of β-Defensin against Virus Infection by Dexamethasone and Phenylalanine Dual-Modified Dendrimer
The dual-modified dendrimer containing dexamethasone (DET) and phenylalanine (Phe) was prepared to deliver plasmid DNA encoding dCas9 and single-guide RNA (sgRNA) for specific upregulation of β-defensin. DET and Phe moieties synergistically enhanced the transfection efficiency and reduced cytotoxicity of dendrimers. Combination of three sgRNAs targeting β-defensin gene demonstrated higher activation efficacy of β-defensin than any single sgRNA and combinations of any two sgRNAs, showing an efficient...
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12h
Treatment of Infected Pseudoarthrosis in a Subtrochanteric Fracture in a Patient with Osteopetrosis
Osteopetrosis is a disease of osteoclasts that results in failure of bone remodeling. Despite the sclerotic radiographic appearance of the thickened cortices and its material hardness, osteopetrotic bone is weak and prone to fracture by minor trauma. We report a case of a subtrochanteric fracture in an osteopetrotic patient, with further pseudoarthrosis and infection. Several surgical procedures were required, with further complications. The outcome of each procedure and the final result are also...
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12h
Splenectomy for Solitary Splenic Metastasis in Recurrent Papillary Thyroid Cancer. A Case Report and Literature Review
Thyroid cancer is the most common endocrine malignancy, presenting with 23 500 new cases per year in the United States. About 7-23% of the patients will present recurrent metastases disease during follow-up. The classic variant of papillary carcinoma is less aggressive compared to its other variants like diffuse sclerosing, tall cell or columnar cell, and insular variants, and the sites to which this metastasizes is already well identified. Metastasis to the spleen is an extremely rare manifestation...
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12h
Brain Death Secondary to Rocky Mountain Spotted Fever Encephalitis
A two-year-old female presented with acutely altered mental status following eight days of fever and rash. She had been camping at an Indiana campground 11 days prior to the onset of illness and was evaluated twice for her fever and rash prior to admission. Laboratory evaluation on admission revealed thrombocytopenia, hyponatremia, and elevated transaminases. The patient developed diffuse cerebral edema, and despite intensive care, the edema led to brain death from Rocky Mountain spotted fever (RMSF)....
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12h
Three-Point Boundary Value Problems for the Langevin Equation with the Hilfer Fractional Derivative
We discuss the existence and uniqueness of solutions for the Langevin fractional differential equation and its inclusion counterpart involving the Hilfer fractional derivatives, supplemented with three-point boundary conditions by means of standard tools of the fixed-point theorems for single and multivalued functions. We make use of Banach’s fixed-point theorem to obtain the uniqueness result, while the nonlinear alternative of the Leray-Schauder type and Krasnoselskii’s fixed-point theorem are...
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12h
Structure Design and Bearing Capacity Analysis for Crawler Chassis of Rice Combine Harvester
Due to the current unstable travel performance and poor driving maneuverability of rice combine harvester crawler chassis with high load in the rice field, the driver’s standard sitting posture model was developed by analyzing the handling of the crawler chassis driving control panel. Based on this model, the joystick length and cab manipulation space layout were designed. The Finite Element Software was used to develop the loading and restraining model of the chassis frame, and then the structural...
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12h
Distributed Task Offloading Game in Multiserver Mobile Edge Computing Networks
With the explosion of data traffic, mobile edge computing (MEC) has emerged to solve the problem of high time delay and energy consumption. In order to cope with a large number of computing tasks, the deployment of edge servers is increasingly intensive. Thus, server service areas overlap. We focus on mobile users in overlapping service areas and study the problem of computation offloading for these users. In this paper, we consider a multiuser offloading scenario with intensive deployment of edge...
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12h
Predictive Study of Tuberculosis Incidence by ARMA Model Combined with Air Pollution Variables
China has the second largest number of tuberculosis (TB) cases in the world, and the Xinjiang province has the highest TB incidence in China. Urumqi is the capital city of Xinjiang; good TB prevention and control in Urumqi can provide an example for other parts of Xinjiang, considering that predicting the TB incidence is the prerequisite of prevention and control; therefore, it is necessary to do a prediction study on TB incidence in Urumqi. In this paper, based on the data of TB incidence and air...
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12h
Dynamical System Perspective of Cosmological Models Minimally Coupled with Scalar Field
The stability criteria for the dynamical system of a homogeneous and isotropic cosmological model are investigated with the interaction of a scalar field in the presence of a perfect fluid. In this paper, we depict the dynamical system perspective to study qualitatively the scalar field cosmology under two special cases, with and without potential. In the absence of potential, we get a two-dimensional dynamical system, and we study the analytical as well as geometrical behavior. For the dynamical...
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12h
Exact Combined Solutions for the ()-Dimensional Dispersive Long Water-Wave Equations
The homogeneous balance of undetermined coefficient (HBUC) method is presented to obtain not only the linear, bilinear, or homogeneous forms but also the exact traveling wave solutions of nonlinear partial differential equations. Linear equation is obtained by applying the proposed method to the ()-dimensional dispersive long water-wave equations. Accordingly, the multiple soliton solutions, periodic solutions, singular solutions, rational solutions, and combined solutions of the ()-dimensional dispersive...
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12h
Paternal Resistance Training Induced Modifications in the Left Ventricle Proteome Independent of Offspring Diet
Ancestral obesogenic exposure is able to trigger harmful effects in the offspring left ventricle (LV) which could lead to cardiovascular diseases. However, the impact of the father’s lifestyle on the offspring LV is largely unexplored. The aim of this study was to investigate the effects of 8 weeks of paternal resistance training (RT) on the offspring left ventricle (LV) proteome exposed to control or high-fat (HF) diet. Wistar rats were randomly divided into two groups: sedentary fathers and trained...
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12h
The Attenuation of Traumatic Brain Injury via Inhibition of Oxidative Stress and Apoptosis by Tanshinone IIA
Traumatic brain injury (TBI) is a major source of mortality and long-term disability worldwide. The mechanisms associated with TBI development are poorly understood, and little progress has been made in the treatment of TBI. Tanshinone IIA is an effective agent to treat a variety of disorders; however, the mechanisms of Tanshinone IIA on TBI remain unclear. The aim of the present study was to investigate the therapeutic potential of Tanshinone IIA on TBI and its underlying molecular mechanisms. Changes...
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12h
Mulberry Fruit Prevents Diabetes and Diabetic Dementia by Regulation of Blood Glucose through Upregulation of Antioxidative Activities and CREB/BDNF Pathway in Alloxan-Induced Diabetic Mice
Although mulberry fruit has various beneficial effects, its effect on diabetes-related dementia remains unknown. We investigated whether the ethyl acetate fraction of ethanolic extract of mulberry fruit (MFE) could alleviate biochemical and behavioral deficits in alloxan-induced diabetic mice. In the diabetic mice, MFE considerably abolished multiple deficits, e.g., body weight reduction; water and food intake increase; and hyperglycemia, hyperlipidemia, hypoinsulinism, and hypertrophy of the liver,...
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12h
Towards Analysis and Optimization of Electrospun PVP (Polyvinylpyrrolidone) Nanofibers
In this study, the polymeric nanofibers of polyvinylpyrrolidone (PVP) were manufactured using the electrospinning technique. The electrospinning process parameters such as voltage, polymer concentration, rotational speed of the collecting drum, collecting distance, and flow rate were optimized to obtain the minimum fiber diameter for sound absorption applications. The effects of these parameters on the fiber diameter as output responses were investigated by analysis of variance (ANOVA) and Taguchi’s...
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12h
Detection and Prognosis of Prostate Cancer Using Blood-Based Biomarkers
Prostate cancer (PCa) is second only to lung cancer as a cause of death. Clinical assessment of patients and treatment efficiency therefore depend on the disease being diagnosed as early as possible. However, due to issues regarding the use of prostate-specific antigen (PSA) for screening purposes, PCa management is among the most contentious of healthcare matters. PSA screening is problematic primarily because of diagnosis difficulties and the high rate of false-positive biopsies. Novel PCa biomarkers,...
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12h
Risk of Severe Adverse Maternal and Neonatal Outcomes in Deliveries with Repeated and Primary Cesarean Deliveries versus Vaginal Deliveries: A Cross-Sectional Study
Objective. To determine risks of severe adverse maternal and neonatal outcomes in women with repeated cesarean delivery (CD) and primary CD compared with those with vaginal delivery (VD). Methods. Data of this cross-sectional study were extracted from 2,262 pregnant women who gave birth between August 2014 and December 2016, at Srinagarind Hospital, Khon Kaen University. Severe maternal outcomes were categorized based on the World Health Organization criteria. Adjusted odds ratio (aOR) and 95% confidence...
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12h

Fluid Structure Interaction on Paravalvular Leakage of Transcatheter Aortic Valve Implantation Related to Aortic Stenosis: A Patient-Specific Case
This study investigated the impact of paravalvular leakage (PVL) in relation to the different valve openings of the transcatheter aortic valve implantation (TAVI) valve using the fluid structure interaction (FSI) approach. Limited studies were found on the subject of FSI with regards to TAVI-PVL condition, which involves both fluid and structural responses in coupling interaction. Hence, further FSI simulation with the two-way coupling method is implemented to investigate the effects of hemodynamics...
Hindawi Publishing Corporation
12h
From ACTH-Dependent to ACTH-Independent Cushing’s Syndrome from a Malignant Mixed Corticomedullary Adrenal Tumor: Potential Role of Embryonic Stem Cells
Context. Truly, mixed corticomedullary adrenal tumors (MCATs) may not come from colliding tumors but from a single stem cell. Objective. To report the immunohistochemical and molecular evaluation of a patient with ectopic ACTH syndrome (EAS) from a MCAT which has single cells with features of both 96 medullary and cortical differentiation. Case Description and Methods. A 16-year-old woman presented with severe EAS and a large right MCAT composed of ACTH-secreting cells resembling pheochromocytoma...
Hindawi Publishing Corporation
12h
Existence of Positive Weak Solutions for a New Class of Laplacian Nonlinear Elliptic System with Sign-Changing Weights
In this paper, by using subsuper solutions method, we study the existence of weak positive solutions for a new class of Laplacian nonlinear elliptic system in bounded domains, when ,, and are sign-changing functions that maybe negative near the boundary, without assuming sign conditions on , and .
Hindawi Publishing Corporation
12h
Evaluation of an Epoxy-Based Nanosilicacomposite Lining in H2SO4 Solution for Anticorrosion of Sewerage Concrete Structures
This work presents the performance of a SiO2-epoxy nanocomposite lining for the anticorrosion of the concrete structures in sewer networks. Nanocomposite lining on the concrete substrate surface of the 15 phr (part per hundred epoxy resin) amine-cured epoxy polymer containing 3.0 phr of nano-SiO2 was prepared by intercalating epoxy into the SiO2 via direct mixing process. The silica exfoliation was monitored by X-ray diffraction (XRD) and transmission electron microscopy (TEM). The barrier feature...
Hindawi Publishing Corporation
12h
Flavonoids in Ageratum conyzoides L. Exert Potent Antitumor Effects on Human Cervical Adenocarcinoma HeLa Cells In Vitro and In Vivo
The Ageratum conyzoides L. (A. conyzoides) is commonly used as a traditional medicine, and its antitumor effects have also been studied. However, the functional roles of flavonoids in A. conyzoides in antitumor activities have not been clarified. The present study is aimed at investigating the biological effects of flavonoids in A. conyzoides on human cervical adenocarcinoma. Firstly, we detected that flavonoids in A. conyzoides significantly inhibited the proliferation, invasion, migration, and...
Hindawi Publishing Corporation
12h
An Eco-Inefficiency Dominance Probability Approach for Chinese Banking Operations Based on Data Envelopment Analysis
Data envelopment analysis (DEA) has proven to be a powerful technique for assessing the relative performance of a set of homogeneous decision-making units (DMUs). A critical feature of conventional DEA approaches is that only one or several sets of optimal virtual weights (or multipliers) are used to aggregate the ratio performance efficiencies, and thus, the efficiency scores might be too extreme or even unrealistic. Alternatively, this paper aims at developing a new performance dominance probability...
Hindawi Publishing Corporation
12h
A Mixed Discontinuous Galerkin Method for the Helmholtz Equation
In this paper, we introduce and analyze a mixed discontinuous Galerkin method for the Helmholtz equation. The mixed discontinuous Galerkin method is designed by using a discontinuous finite element pair for the flux variable and the scattered field with . We can get optimal order convergence for the flux variable in both -like norm and norm and the scattered field in norm numerically. Moreover, we conduct the numerical experiments on the Helmholtz equation with perturbation and the rectangular...
Hindawi Publishing Corporation
12h
Increasing Oxygen Mass Fraction in Blind Headings of a Plateau Metal Mine by Oxygen Supply Duct Design: A CFD Modelling Approach
Hypoxia problem has always been a difficult point in plateau tunneling projects. To solve this problem, a blind heading face in a plateau metal mine in western China was taken as the physical model, and the computational fluid dynamics was used to analyze the oxygen mass fraction distribution and oxygen-increasing effect in 1 m, 3 m, and 5 m roadway sections from the heading face. The optimal ventilation system was first built to obtain the optimum height and length of the airflow ducts. Then different...
Hindawi Publishing Corporation
12h
How Different Government Subsidy Objects Impact on Green Supply Chain Decision considering Consumer Group Complexity
This paper fully considers the complexity characteristics of the consumer group, such as the heterogeneity of consumer environmental preferences and consumption levels and constructs a two-stage price decision model of green supply chain composed of the manufacturer and retailers. Under the four different scenarios, no government subsidies, government subsidies are given to the manufacturer, government subsidies are given to the green product retailer, and government subsidies are given to green...
Hindawi Publishing Corporation
12h
Low-Frequency Repetitive Transcranial Magnetic Stimulation for the Treatment of Chronic Tinnitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Background. Chronic tinnitus affects approximately 10-15% of the population. Low-frequency repetitive transcranial magnetic stimulation (rTMS) has been considered as a promising and well-tolerated therapeutic strategy for chronic tinnitus. However, a recent large-scale multicenter clinical trial showed a negative result. Objective. This systematic review is aimed at assessing the efficacy and safety of low-frequency rTMS in chronic tinnitus. Methods. We searched PubMed, Embase, and Cochrane Library...
Hindawi Publishing Corporation
12h
A Novel Hypogenetic Chaotic Jerk System: Modeling, Circuit Implementation, and Its Application
When revising the polarity and amplitude information in the feedback, a unique hypogenetic jerk system was obtained which has two controllers to switch the equilibria between stable and unstable. After providing some basic dynamical analysis, an electronic circuit was implemented, and the phase trajectory in the oscilloscope agrees with the numerical simulation. Further exploration shows that this unique chaotic system has superior performance as a random number generator or in voice encryption application.
Hindawi Publishing Corporation
12h
Research Advances on Biosynthesis, Regulation, and Biological Activities of Apocarotenoid Aroma in Horticultural Plants
Apocarotenoids, which play important roles in the growth and development of horticultural plants, are produced by the action of carotenoid cleavage oxygenase (CCO) family members or nonenzymatic cleavage actions. Apocarotenoids are commonly found in leaves, flowers, and fruits of many horticultural plants and participate in the formation of pigments, flavors, hormones, and signaling compounds. Some of them are recognized as important aroma components of fruit and flower with aromatic odor, such as...
Hindawi Publishing Corporation
12h
Transient Characteristics of Water-Jet Propulsion with a Screw Mixed Pump during the Startup Process
In order to investigate the transient hydrodynamic characteristics of water-jet propulsion with a screw mixed pump during the startup period and to overcome the difficulties in measuring the transient process parameters over a very short period of time, a method based on a flume experiment combined with computational fluid dynamics (CFD) is proposed. The thrust and torque of the pump-jet propulsion according to mooring status at different rotational speeds were measured by the test, which provided...
Hindawi Publishing Corporation
12h
Integrated Scheduling for Steelmaking Continuous Casting— Hot Rolling Processes considering Hot Chain Logistics
Steelmaking continuous casting (SCC)—hot rolling (HR) is a key process in the production of steel products. It is also a process with large energy consumption. Energy saving has always been an important goal of production scheduling of this process. In this paper, aiming at integrated scheduling optimization for SCC-HR processes, energy saving objective is converted to minimize waiting time of slabs in slab yard, so as to reduce slab temperature loss and achieve the goal of saving energy. An integrated...
Hindawi Publishing Corporation
12h

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