Sun Sep 15, 2019 05:28
Sun Sep 15, 2019 05:28
Sun Sep 15, 2019 05:28
Sun Sep 15, 2019 05:28
Related ArticlesComparison of a clinical-laboratory algorithm, 4t and heparin-induced thrombocytopenia expert probability scores in the diagnosis of heparin-induced thrombocytopenia in the critical care setting. Am J Blood Res. 2019;9(3):25-33 Authors: Younis M, Ya'qoub L, Ali Z, Grover P, Ya'acoub R, Hamarshi MS Abstract BACKGROUND: Several scoring systems are utilized to calculate the pre-test probability of heparin-induced thrombocytopenia (HIT)....
Sun Sep 15, 2019 07:32
Abstract In accordance with Article 6 of Regulation (EC) No 396/2005, the Agriculture and Horticulture Development Board (AHDB) in the United Kingdom submitted a request to the competent national authority to modify the existing maximum residue level (MRL) for the active substance cyprodinil in rhubarbs. The data submitted in support of the request were found to be sufficient to derive an MRL proposal of 2 mg/kg for rhubarbs. Adequate analytical methods for enforcement are available to control the...
Fri Sep 13, 2019 16:21
Abstract According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance pyridalyl. To assess the occurrence of pyridalyl residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Commission Regulation (EU) No 188/2011, as well as the European authorisations reported by Member States (including the supporting...
Fri Sep 13, 2019 16:32
Abstract Background Venous congestion is the most frequently reported complication of free flap tissue transfer in head and neck patient with cancer. Numerous methods are utilized and prompt correction is necessary to prevent flap failure. Methods A 77‐year‐old woman underwent oral cavity resection and neck dissection for squamous cell carcinoma followed by radial forearm free flap for reconstruction. Three days later, the flap became congested and surgical exploration revealed extensive...
Thu Sep 12, 2019 12:09
Thu Sep 12, 2019 13:13
Abstract Background There is a paucity of literature characterizing outcomes in older adult patients with head and neck cancer (HNC). This study aims to describe patients from this group, their adherence to National Comprehensive Cancer Network (NCCN) adjuvant treatment guidelines, and the impact of guideline adherence on overall survival (OS). Methods In this retrospective cohort study, we reviewed all patients ≥80 years old with HNC who underwent surgery with curative intent from 2008...
Thu Sep 12, 2019 13:48
Abstract Background Solid organ transplant recipients are known to be at an increased risk of cancer development, but research on head and neck cancer in transplant recipients has been limited and prior risk assessments may not be accurate. Methods A retrospective review using a national Veterans Administration database to query outpatient problem lists for ICD codes indicating solid organ transplant and subsequent diagnosis of head and neck cancer. Results In a study of 30 939 656...
Thu Sep 12, 2019 13:54
The cover image is based on the Original Article Comparison of hypocalcemia rates between LigaSure and clamp‐and‐tie hemostatic technique in total thyroidectomies by Feng‐Yu Chiang et al., https://doi.org/10.1002/hed.25884
Thu Sep 12, 2019 13:19
Abstract Background To investigate the prognostic significance of paranasal sinus invasion in nasopharyngeal carcinoma (NPC) patients. Methods Patients with NPC after intensity‐modulated radiotherapy from 2010 to 2013 were identified (n = 1225). Clinical features and magnetic resonance images were analyzed. Results Paranasal sinus invasion was identified in 182/1225 patients (14.9%). Multivariate analysis showed that paranasal sinus invasion was an independent factor for overall survival,...
Fri Sep 13, 2019 16:40
Abstract Background Neoadjuvant chemotherapy (NAC) trials in endemic regions of nasopharyngeal carcinoma (NPC) found improved survival, but studies are lacking in nonendemic regions. We assessed whether adding NAC to concurrent chemoradiation (CRT) improves overall survival (OS), especially in high‐risk nonendemic patients. Methods Definitively treated NPC patients (n = 5424) from the National Cancer Database were analyzed for predictors of NAC and NAC effects on OS with multivariate Cox...
Sat Sep 14, 2019 13:43
Abstract With the prolific uptake of simulation‐based training courses, this systematic review aims to identify the available microsurgical simulation and training models, their status of validation, associated studies, and levels of evidence (LoE) for each training model, thereby establishing a level of recommendation (LoR). MEDLINE, Embase, and the Cochrane Library databases were searched for English language articles, describing microsurgery simulators and/or validation studies. All studies were...
Thu Sep 12, 2019 18:23
Abstract Introduction The anterolateral thigh (ALT) flap is considered a workhorse reconstructive option; however, it is encumbered by its bulkiness that can result in poor final outcome and need for revision surgery. The aim of the present study was to compare the standard cutaneous ALT free flap and sandwich fascial ALT (SALT) free flap, raised harvesting between the Scarpa's fascia and the crural fascia, for distal extremity soft tissue reconstruction, including pre‐ intra‐ and post‐operative...
Sat Sep 14, 2019 15:36
Publication date: Available online 14 September 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Ping Gong, Pengfei Song, Chengwu Huang, U-Wai Lok, Shanshan Tang, Yue Yu, Duane D. Meixner, Kathryn J. Ruddy, Karthik Ghosh, Robert T. Fazzio, Wenwu Ling, Shigao ChenAbstractTumor angiogenesis plays an important role during breast tumor growth. However, conventional Doppler has limited sensitivity to detect small blood vessels, resulting in a large overlap of Doppler features between benign...
Sun Sep 15, 2019 12:45
Publication date: Available online 14 September 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Omer Aydin, Parwathy Chandran, Rebecca R. Lorsung, Gadi Cohen, Scott R. Burks, Joseph A. FrankAbstractNon-ablative pulsed focused ultrasound (pFUS) targets non-thermal forces that activate local molecular and cellular immune responses. Optimal parameters to stimulate immunotherapeutic tumor microenvironments (TME) and responses in different tumor types remain uninvestigated. Flank B16 murine...
Sun Sep 15, 2019 12:45
Abstract Background The best treatment strategy for disturbing temporomandibular clicking sounds is not known. Objectives The aim was to evaluate the effect of exercise, and bite splint therapy, respectively, in patients with symptomatic disc displacement with reduction. Methods The study was a randomized clinical trial of subjects with temporomandibular joint (TMJ) clicking sounds with a reported severity/intensity of ≥4 on a numerical rating scale (0‐10) and signs fulfilling the Research...
Sat Sep 14, 2019 16:44
Abstract Objective The purpose of this study is to develop an index to measure oral and maxillofacial frailty in older adults as an acceptable screening tool. Methods Three hundred adults (aged ≥50 years) participated in this study by telephone interview. Ten candidate items for the Oral and Maxillofacial Frailty Index (OMFI) and 20 matched detailed items for oral and maxillofacial functions were asked. Information about sociodemographic and oral health‐related variables was also obtained....
Sat Sep 14, 2019 16:54
Abstract Background Tooth wear, has been recognized as a growing oral health problem in children and adolescents, with erosion often cited as the main cause of the tooth wear. Most studies on tooth wear have been conducted on children and adolescents, and only few studies focus on adults. Our aim was to study the prevalence of different types of tooth wear in an adult population and investigate related factors to tooth wear. Methods A total of 831 adults in Sweden participated in the study...
Sat Sep 14, 2019 17:04
Abstract Food perception is a multimodal sensation which implies cross‐modal interplays. Tactile, thermal, painful and kinesthetic stimuli arising from food intake may impact on flavor perception, especially taste perception. The influence of oral somatosensory signals on food taste perception remains unclear. The aim of the present systematic review was to appraise the effects of oral mechanical, thermal, chemical and pain sensations on taste perception. In accordance with the Preferred Reporting...
Sat Sep 14, 2019 17:04
Abstract Background Uncertainties still exist about the role of playing musical instruments on the report of musculoskeletal complaints and headache. Objectives To evaluate the prevalence of and risk indicators for symptoms of temporomandibular disorders, pain in the neck or shoulder, and headache among musicians. Methods A questionnaire was distributed among 50 Dutch music ensembles. Results The questionnaire was completed by 1,470 musicians (response rate 77.0%). Of these,...
Sat Sep 14, 2019 17:04
Abstract Oral maxillofacial defects may always lead to complicated hard and soft tissue loss, including bone, nerve, blood vessels, teeth and skin, which are difficult to restore and severely influence the life quality of patients. Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are emerging as potential solutions for complex tissue regeneration through cell‐free therapies. In this review, we highlight the functional roles of EVs in the regenerative medicine...
Sat Sep 14, 2019 18:29
Related ArticlesPretreatment Serum Levels of Soluble Cytokeratin Fragments (Cyfra 21-1, TPS, MonoTotal) in Relation to Clinical and Pathobiological Aspects of Head and Neck Squamous Cell Carcinomas. Anticancer Res. 2019 Sep;39(9):5171-5177 Authors: Kalfert D, Ludvik J, Kucera R, Topolcan O, Celakovsky P, Pesta M, Kholova I, Plzak J, Ludvikova M Abstract BACKGROUND/AIM: The aim of this study was to analyze the pretreatment cytokeratin serum levels in...
Sun Sep 15, 2019 13:00
35 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/09/13PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Sep 13, 2019 13:47
35 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/09/13PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Sep 13, 2019 15:49
36 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/09/14PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Sep 14, 2019 14:22
Related ArticlesSilver, titanium dioxide, and zinc oxide nanoparticles trigger miRNA/isomiR expression changes in THP-1 cells that are proportional to their health hazard potential. Nanotoxicology. 2019 Sep 13;:1-16 Authors: Ndika J, Seemab U, Poon WL, Fortino V, El-Nezami H, Karisola P, Alenius H Abstract After over a decade of nanosafety research, it is indisputable that the vast majority of nano-sized particles induce a plethora of adverse cellular...
Sun Sep 15, 2019 13:01
Related ArticlesNeutrophil Extracellular Traps Drive Mitochondrial Homeostasis in Tumors to Augment Growth. Cancer Res. 2019 Sep 13;: Authors: Yazdani HO, Roy E, Comerci AJ, van der Windt DJ, Zhang H, Huang H, Loughran P, Shiva S, Geller DA, Bartlett DL, Tsung A, Sheng T, Simmons RL, Tohme S Abstract Neutrophil infiltration and neutrophil extracellular traps (NETs) in solid cancers are associated with poorer prognosis but the mechanisms are incompletely...
Sun Sep 15, 2019 13:01
Related ArticlesInsulin and β-adrenergic receptors mediate lipolytic and anti-lipolytic signalling that is not altered by type 2 diabetes in human adipocytes. Biochem J. 2019 Sep 13;: Authors: Strålfors P, Jönsson C, Castor Batista AP, Kjølhede P Abstract Control of fatty acid storage and release in adipose tissue is fundamental in energy homeostasis and the development of obesity and type 2 diabetes. We here take the whole signalling network into account...
Sun Sep 15, 2019 13:01
Related ArticlesKIR Polymorphism Modulates the Size of the Adaptive NK Cell Pool in Human Cytomegalovirus-Infected Individuals. J Immunol. 2019 Sep 13;: Authors: Manser AR, Scherenschlich N, Thöns C, Hengel H, Timm J, Uhrberg M Abstract Acute infection with human CMV (HCMV) induces the development of adaptive NKG2C+ NK cells. In some cases, large expansions of this subset, characterized by coexpression of HLA-C-specific KIR, are stably maintained during...
Sun Sep 15, 2019 13:01
Related ArticlesActivated α2-Macroglobulin Regulates LRP1 Levels at the Plasma Membrane through the Activation of a Rab10-dependent Exocytic Pathway in Retinal Müller Glial Cells. Sci Rep. 2019 Sep 13;9(1):13234 Authors: Jaldín-Fincati JR, Actis Dato V, Díaz NM, Sánchez MC, Barcelona PF, Chiabrando GA Abstract Activated α2-macroglobulin (α2M*) and its receptor, low-density lipoprotein receptor-related protein 1 (LRP1), have been linked to proliferative...
Sun Sep 15, 2019 13:01
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