Related ArticlesPatient safety analysis in radiation burden of head computed tomography imaging in 1,185 neurosurgical inpatients. World Neurosurg. 2019 Sep 11;: Authors: Sheppard JP, Duong C, Romiyo P, Azzam D, Alkhalid Y, Nguyen T, Babayan D, Lagman C, Sun MZ, Prashant GN, Beckett JS, Yang I Abstract OBJECTIVE: We performed a retrospective analysis in a cohort of 1,185 patients at our institution who were identified as undergoing one or more head CT...
Sun Sep 15, 2019 14:17
Related ArticlesAn Anatomical Feasibility Study for Revascularization of the Ophthalmic Artery. Part II: Intraorbital Segment. World Neurosurg. 2019 Sep 11;: Authors: Rubio RR, Vigo V, Gandhi S, Tabani H, Meybodi AT, Winkler EA, Abla AA, Lawton MT, Benet A Abstract INTRODUCTION: Distal ophthalmic artery (OpA) aneurysms are a rare subset of vascular lesions with lack of optimal treatment. The management of these aneurysms may require complete occlusion...
Sun Sep 15, 2019 14:17
Related ArticlesSuppression of NLRP3 and NF-κB signaling pathways by α-Cyperone via activating SIRT1 contributes to attenuation of LPS-induced acute lung injury in mice. Int Immunopharmacol. 2019 Sep 11;76:105886 Authors: Liu X, Jin X, Yu D, Liu G Abstract α-Cyperone is the volatile oil component in Cyperus rotundus L. The previous reports had shown the inhibition of α-Cyperone on NF-κB signaling in LPS-stimulated RAW264.7 cells. However, it is still...
Sun Sep 15, 2019 14:17
Treatment outcomes in oropharynx cancer patients who did not complete planned curative radiotherapy.
Related ArticlesTreatment outcomes in oropharynx cancer patients who did not complete planned curative radiotherapy. Oral Oncol. 2019 Sep 11;97:124-130 Authors: Alfaraj F, Craig T, Huang SH, O'Sullivan B, Su J, Bayley A, Bratman S, Cho J, Giuliani M, Kim J, Ringash J, Waldron J, Hansen A, de Almeida J, Perez-Ordonez B, Weinreb I, Tong L, Xu W, Hope A Abstract PURPOSE: To evaluate outcomes in oropharyngeal cancer (OPC) patients who did not complete their...
Sun Sep 15, 2019 14:17
Related ArticlesIdentification of different clinical faces of obstructive sleep apnea in children. Int J Pediatr Otorhinolaryngol. 2019 Aug 06;127:109621 Authors: Wu Y, Feng G, Xu Z, Li X, Zheng L, Ge W, Ni X Abstract OBJECTIVE: This study aimed to identify the heterogeneity of obstructive sleep apnea syndrome clinical presentation in children. PARTICIPANTS: Children who were 3-14 years old and with obstructive sleep apnea syndrome after polysomnography...
Sun Sep 15, 2019 14:17
Publication date: Available online 13 September 2019Source: Journal of VoiceAuthor(s): HaKyung Kim, ShaoHua Gao, Bin Yi, RunJie Shi, Qin Wan, ZhaoMing HuangAbstractPurposeThe Dysphonia Severity Index (DSI) is an objective multiparameter index of voice quality that measures and describes overall voice quality. Some studies have suggested that the reliability of devices for DSI measurement should be examined. We explored the feasibility of DSI measurements using the Dr. Speech (DRS) device, verified...
Sat Sep 14, 2019 18:56
Publication date: Available online 13 September 2019Source: Journal of VoiceAuthor(s): Mary J. Sandage, Shuoyang Wang, Guanqun CaoAbstractThe primary aim of this research was to quantify the degree to which the upper airway temperature changes with singing warm-up. Based on prior upper airway thermoregulation research it was hypothesized that upper airway temperature would not significantly increase during singing warm up when compared to prewarm up and recovery phases. Ten participants completed...
Sat Sep 14, 2019 18:56
Publication date: Available online 14 September 2019Source: Journal of VoiceAuthor(s): Lady Catherine Cantor-Cutiva, Pasquale Bottalico, Charles Nudelman, Jossemia Webster, Eric J. HunterSummaryBackgroundIn addition to language differences in fundamental frequency between bilinguals and monolinguals, studies have also included other acoustic parameters to analyze differences in voice production associated with the language spoken.AimTo identify differences in voice acoustic parameters during English...
Sat Sep 14, 2019 18:56
Publication date: Available online 14 September 2019Source: Journal of VoiceAuthor(s): Supraja Anand, Pasquale Bottalico, Camille GrayAbstractObjectivesThe goals of the study were to (a) examine vocal fatigue in speech-language pathology students through subjective and objective measures following a novel 30-minute vocal loading task (VLT) and (b) evaluate the effects of psychosocial factors on vocal fatigue.MethodsSeventeen speech-language pathology students completed a 30-minute VLT using the LingWAVES...
Sun Sep 15, 2019 13:16
Related ArticlesComprehensive evaluation of transcriptome-based cell-type quantification methods for immuno-oncology. Bioinformatics. 2019 Jul 15;35(14):i436-i445 Authors: Sturm G, Finotello F, Petitprez F, Zhang JD, Baumbach J, Fridman WH, List M, Aneichyk T Abstract MOTIVATION: The composition and density of immune cells in the tumor microenvironment (TME) profoundly influence tumor progression and success of anti-cancer therapies. Flow cytometry,...
Fri Sep 13, 2019 13:22
Related ArticlesValidation of the Patient Empowerment Strategies Questionnaire (PES-Q) in Greek adult patients with chronic insomnia: a pilot study on basic psychometric values. Prim Health Care Res Dev. 2019 Sep 12;20:e130 Authors: Tsoli S, Galanakis M, Koumarianou A, Makris G, Kapogiannis A, Chrousos G Abstract AIM: The objectives of this study were to validate the Patient Empowerment Strategies Questionnaire (PES-Q) in a Greek sample and to study...
Fri Sep 13, 2019 13:22
Related ArticlesExpert Elicitation to Inform a Cost-Effectiveness Analysis of Screening for Renal Cancer. Value Health. 2019 Sep;22(9):981-987 Authors: Rossi SH, Blick C, Nathan P, Nicol D, Stewart GD, Wilson ECF Abstract BACKGROUND: Population screening for renal cell carcinoma (RCC) using ultrasound has the potential to improve survival outcomes; however, a cost-effectiveness analysis (CEA) has yet to be performed. Owing to the lack of existing evidence,...
Fri Sep 13, 2019 13:22
Related ArticlesFatigue, quality of life and metabolic changes in men treated with first-line enzalutamide versus abiraterone plus prednisolone for metastatic castration-resistant prostate cancer (HEAT): a randomised trial protocol. BMJ Open. 2019 Sep 11;9(9):e030218 Authors: Kvorning Ternov K, Sønksen J, Fode M, Lindberg H, Kistorp CM, Bisbjerg R, Palapattu G, Østergren PB Abstract INTRODUCTION: Enzalutamide and abiraterone acetate plus prednisolone...
Fri Sep 13, 2019 13:22
Related ArticlesProstate-Specific Membrane Antigen Ligand Positron-Emission Tomography in Men with Nonmetastatic Castration-Resistant Prostate Cancer. Clin Cancer Res. 2019 Sep 11;: Authors: Fendler WP, Weber M, Iravani A, Hofman MS, Calais J, Czernin J, Ilhan H, Saad F, Small EJ, Smith MR, Perez PM, Hope TA, Rauscher I, Londhe A, Lopez-Gitlitz A, Cheng S, Maurer T, Herrmann K, Eiber M, Hadaschik B Abstract PURPOSE: Systemic androgen-signaling inhibition...
Fri Sep 13, 2019 13:22
Related ArticlesMass cytometry reveals species-specific differences and a new level of complexity for immune cells in the prostate. Am J Clin Exp Urol. 2019;7(4):281-296 Authors: Fox JJ, Navarro HI, Hashimoto T, Garcia AJ, Goldstein AS Abstract Chronic inflammation in the benign prostate has been associated with a higher risk of developing prostate cancer. While a range of immune lineages is found in the prostate including T cells, B cells and myeloid...
Fri Sep 13, 2019 13:22
Related ArticlesQuality of life in prostate cancer patients receiving particle radiotherapy: A review of the literature. Int J Urol. 2019 Sep 11;: Authors: Kawamura H, Kubo N, Sato H, Miyasaka Y, Matsui H, Ito K, Suzuki K, Ohno T Abstract Proton and carbon ion radiotherapy for the treatment of prostate cancer is associated with a lower incidence of adverse events than conventional radiotherapy. There are few reports on the quality of life of patients...
Fri Sep 13, 2019 13:22
Related ArticlesNear-infrared spectroscopy in the diagnosis of testicular torsion: valuable modality or waste of valuable time? A systematic review. ANZ J Surg. 2019 Sep 11;: Authors: Laher A, Swart M, Honiball J, Perera M, Lawrentschuk N, Adam A Abstract BACKGROUND: Testicular torsion (TT) is a urological emergency that affects one in 4000 males younger than 25 years. Delays in the management of TT may result in testicular ischaemia, testicular necrosis,...
Fri Sep 13, 2019 13:22
Related ArticlesSarcoma patients' quality of life from diagnosis to yearly follow-up: experience from an Italian tertiary care center. Future Oncol. 2019 Sep 12;: Authors: Maggi G, Terrenato I, Giacomelli L, Zoccali C, Condoleo MF, Falcicchio C, Baldi J, Vari S, Ferraresi V, Biagini R, Pugliese P Abstract Aim: To investigate sarcoma patients' perception of quality of life and psychosocial distress across the different disease's stages. Patients &...
Fri Sep 13, 2019 14:20
Related ArticlesA Phase III open-label trial to evaluate efficacy and safety of CPI-613 plus modified FOLFIRINOX (mFFX) versus FOLFIRINOX (FFX) in patients with metastatic adenocarcinoma of the pancreas. Future Oncol. 2019 Sep 12;: Authors: Philip PA, Buyse ME, Alistar AT, Lima CM, Luther S, Pardee TS, Cutsem EV Abstract Devimistat (CPI-613®) is a novel lipoate analog that inhibits the tricarboxcylic acid cycle at two key carbon entry points. Through...
Fri Sep 13, 2019 14:20
Related ArticlesDevimistat in combination with high dose cytarabine and mitoxantrone compared with high dose cytarabine and mitoxantrone in older patients with relapsed/refractory acute myeloid leukemia: ARMADA 2000 Phase III study. Future Oncol. 2019 Sep 12;: Authors: Pardee TS, Luther S, Buyse M, Powell BL, Cortes J Abstract Devimistat (CPI-613®) is an intravenously administered, novel lipoate analog that inhibits two key tricarboxcylic acid (TCA)...
Fri Sep 13, 2019 14:20
Related ArticlesOScc: an online survival analysis web server to evaluate the prognostic value of biomarkers in cervical cancer. Future Oncol. 2019 Sep 12;: Authors: Wang Q, Zhang L, Yan Z, Xie L, An Y, Li H, Han Y, Zhang G, Dong H, Zheng H, Zhu W, Li Y, Wang Y, Guo X Abstract Aim: To establish a web server that can mutually validate prognostic biomarkers of cervical cancer. Methods: Four datasets including expression profiling and relative clinical follow-up...
Fri Sep 13, 2019 14:20
Related ArticlesSurvival nomogram for patients with initially diagnosed metastatic non-small-cell lung cancer: a SEER-based study. Future Oncol. 2019 Sep 12;: Authors: Wang Y, Pang Z, Chen X, Bie F, Wang Y, Wang G, Liu Q, Du J Abstract Aim: Prognosis of patients with metastatic non-small-cell lung cancer differ widely. Methods: All patients were randomly divided into training or validation cohort. Cox-regression analyses were conducted to select independent...
Fri Sep 13, 2019 14:20
Related ArticlesThe NEOLETEXE trial: a neoadjuvant cross-over study exploring the lack of cross resistance between aromatase inhibitors. Future Oncol. 2019 Sep 12;: Authors: Bahrami N, Sauer T, Engebretsen S, Aljabri B, Bemanian V, Lindstrøm J, Lüders T, Kristensen V, Lorentzen A, Loeng M, Ødegård HP, Kvaløy JØ, Vestøl IB, Geisler SB, Gravdehaug B, Gundersen JM, Geisler J Abstract The aromatase inhibitor letrozole (Femar®/Femara®) and the aromatase inactivator...
Fri Sep 13, 2019 14:20
Related ArticlesAcellular fish skin matrix on thin-skin graft donor sites: a preliminary study. J Wound Care. 2019 Sep 02;28(9):624-628 Authors: Badois N, Bauër P, Cheron M, Hoffmann C, Nicodeme M, Choussy O, Lesnik M, Poitrine FC, Fromantin I Abstract OBJECTIVE: Surgery for head and neck cancer often requires free flap reconstructions, whose harvesting site often requires a thin-skin graft. Wounds from the thin-skin donor site are comparable to an intermediate...
Fri Sep 13, 2019 14:20
Related ArticlesRadiation hardness of cadmium telluride solar cells in proton therapy beam mode. PLoS One. 2019;14(9):e0221655 Authors: Cho S, Ahn SH, Cho IJ, Kim YH, Jeong JU, Yoon MS, Ahn SJ, Chung WK, Nam TK, Song JY Abstract We evaluated the durability of cadmium telluride (CdTe) solar cells upon proton beam irradiation as well as the possibility of achieving a dosimeter usable in proton beam therapy by applying 100 MeV of pencil beam scanning (PBS)...
Fri Sep 13, 2019 14:20
Related ArticlesEffects of gold nanoprism-assisted human PD-L1 siRNA on both gene down-regulation and photothermal therapy on lung cancer. Acta Biomater. 2019 Sep 09;: Authors: Liu B, Cao W, Qiao G, Yao S, Pan S, Wang L, Yue C, Ma L, Liu Y, Cui D Abstract Gold nanoprisms (GNPs) have been broadly studied for the potential applications in both imaging and treatment on tumors due to their special characteristics. Herein we reported that a new nanoplatform...
Fri Sep 13, 2019 14:20
Related ArticlesCan radiomics help to predict skeletal muscle response to chemotherapy in stage IV non-small cell lung cancer? Eur J Cancer. 2019 Sep 09;120:107-113 Authors: de Jong EEC, Sanders KJC, Deist TM, van Elmpt W, Jochems A, van Timmeren JE, Leijenaar RTH, Degens JHRJ, Schols AMWJ, Dingemans AC, Lambin P Abstract BACKGROUND: Muscle depletion negatively impacts treatment efficacy and survival rates in cancer. Prevention and timely treatment of...
Fri Sep 13, 2019 14:20
Related ArticlesCytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma: How to Apply New Evidence in Clinical Practice. Oncology. 2019 Sep 12;:1-9 Authors: Soares A, Maia MC, Vidigal F, Marques Monteiro FS Abstract Cytoreductive nephrectomy (CN) followed by systemic therapy had been considered the standard of care for metastatic renal cell carcinoma (mRCC) patients since two clinical trials established its role during the cytokines era. With introduction...
Fri Sep 13, 2019 14:20
Related ArticlesImmunotherapy: A New (and Old) Approach to Treatment of Soft Tissue and Bone Sarcomas. Oncologist. 2018 01;23(1):71-83 Authors: Nathenson MJ, Conley AP, Sausville E Abstract Soft tissue and bone sarcomas are a rare and heterogeneous form of cancer. With standard of care treatment options including surgery, radiation, and chemotherapy, the long-term survival is still low for high-risk soft tissue sarcoma patients. New treatment strategies...
Sat Sep 14, 2019 13:33
Related ArticlesSarcopenia Is Associated with Quality of Life and Depression in Patients with Advanced Cancer. Oncologist. 2018 01;23(1):97-104 Authors: Nipp RD, Fuchs G, El-Jawahri A, Mario J, Troschel FM, Greer JA, Gallagher ER, Jackson VA, Kambadakone A, Hong TS, Temel JS, Fintelmann FJ Abstract BACKGROUND: Patients with advanced cancer often experience muscle wasting (sarcopenia), yet little is known about the characteristics associated with sarcopenia...
Sat Sep 14, 2019 13:33
Related ArticlesLocal Treatment of Breast Cancer Liver Metastasis. Cancers (Basel). 2019 Sep 11;11(9): Authors: Bale R, Putzer D, Schullian P Abstract Breast cancer represents a leading cause of death worldwide. Despite the advances in systemic therapies, the prognosis for patients with breast cancer liver metastasis (BCLM) remains poor. Especially in case of failure or cessation of systemic treatments, surgical resection for BCLMs has been considered...
Sat Sep 14, 2019 13:33
Related ArticlesAnti-Tumor Potential of IMP Dehydrogenase Inhibitors: A Century-Long Story. Cancers (Basel). 2019 Sep 11;11(9): Authors: Naffouje R, Grover P, Yu H, Sendilnathan A, Wolfe K, Majd N, Smith EP, Takeuchi K, Senda T, Kofuji S, Sasaki AT Abstract The purine nucleotides ATP and GTP are essential precursors to DNA and RNA synthesis and fundamental for energy metabolism. Although de novo purine nucleotide biosynthesis is increased in highly proliferating...
Sat Sep 14, 2019 13:33
Related ArticlesThe Effect of the Pubertal Stage on Irisin Levels in Male Adolescents: A Novel Myokine J Clin Res Pediatr Endocrinol. 2019 Sep 13;: Authors: Taş D, Akman Öden A, Akgül S, Metin ZE, Pınar A, Kanbur N Abstract Objective: Irisin is a recently discovered protein and is defined as adipomyokine. The relation of irisin with carbohydrate metabolism and other hormone parameters have been investigated; however, studies evaluating the relationship...
Sat Sep 14, 2019 13:33
Related ArticlesNicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation: a pragmatic, randomised trial. Lancet Respir Med. 2019 Sep 09;: Authors: Walker N, Parag V, Verbiest M, Laking G, Laugesen M, Bullen C Abstract BACKGROUND: Combination nicotine replacement therapy shows additive cessation benefits. We aimed to find out the effectiveness of combining nicotine patches with an e-cigarette (with and without...
Sat Sep 14, 2019 13:33
Related ArticlesHealth-related quality of life in transplant ineligible newly diagnosed multiple myeloma patients treated with either thalidomide or lenalidomide-based regimen until progression: a prospective, open-label, multicenter, randomized, phase 3 study. Haematologica. 2019 Sep 12;: Authors: Nielsen LK, Stege C, Lissenberg-Witte B, van der Holt B, Mellqvist UH, Salomo M, Bos G, Levin MD, Visser-Wisselaar H, Hansson M, van der Velden A, Deenik W, Coenen J, Hinge...
Sat Sep 14, 2019 13:33
Related ArticlesGlasdegib plus intensive/nonintensive chemotherapy in untreated acute myeloid leukemia: BRIGHT AML 1019 Phase III trials. Future Oncol. 2019 Sep 13;: Authors: Cortes JE, Dombret H, Merchant A, Tauchi T, DiRienzo CG, Sleight B, Zhang X, Leip EP, Shaik N, Bell T, Chan G, Sekeres MA Abstract Glasdegib, an oral Hedgehog pathway inhibitor, has been associated with significantly improved survival when combined with low-dose cytarabine in patients...
Sat Sep 14, 2019 14:31
Related ArticlesImpact of anti-smoking advertising on health-risk knowledge and quit attempts across 6 European countries from the EUREST-PLUS ITC Europe Survey. Tob Induc Dis. 2018;16:A5 Authors: Nogueira SO, McNeill A, Fu M, Kyriakos CN, Mons U, Fernández E, Zatoński WA, Trofor AC, Demjén T, Tountas Y, Przewoźniak K, Quah ACK, Fong GT, Hitchman SC, Vardavas CI, EUREST-PLUS consortium Abstract INTRODUCTION: Exposure to anti-smoking advertising and its...
Sat Sep 14, 2019 14:31
Related ArticlesPatterns of tobacco use, quit attempts, readiness to quit and self-efficacy among smokers with anxiety or depression: Findings among six countries of the EUREST-PLUS ITC Europe Surveys. Tob Induc Dis. 2018;16:A9 Authors: Petroulia I, Kyriakos CN, Papadakis S, Tzavara C, Filippidis FT, Girvalaki C, Peleki T, Katsaounou P, McNeill A, Mons U, Fernández E, Demjén T, Trofor AC, Herbeć A, Zatoński WA, Tountas Y, Fong GT, Vardavas CI, EUREST-PLUS consortium ...
Sat Sep 14, 2019 14:31
Related ArticlesCigarette brand loyalty among smokers in six European countries: Findings from the EUREST-PLUS ITC Europe Surveys. Tob Induc Dis. 2018;16:A12 Authors: Nogueira SO, Tigova O, Castellano Y, Mons U, Kyriakos CN, McNeill A, Trofor AC, Zatoński WA, Przewoźniak K, Demjén T, Tountas Y, Quah ACK, Fong GT, Fu M, Vardavas CI, Fernández E, EUREST-PLUS consortium Abstract INTRODUCTION: This study aims to describe the degree of smokers' loyalty to...
Sat Sep 14, 2019 14:31
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