Antibiotics, Vol. 8, Pages 160: Do Global Regulators Hold the Key to Production of Bacterial Secondary Metabolites? Antibiotics doi: 10.3390/antibiotics8040160 Authors: Sudarshan Singh Thapa Anne Grove The emergence of multiple antibiotic resistant bacteria has pushed the available pool of antibiotics to the brink. Bacterial secondary metabolites have long been a valuable resource in the development of antibiotics, and the genus Burkholderia has recently emerged as a source of novel...
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Antibiotics, Vol. 8, Pages 159: The Effect of 2-Thiocyanatopyridine Derivative 11026103 on Burkholderia Cenocepacia: Resistance Mechanisms and Systemic Impact Antibiotics doi: 10.3390/antibiotics8040159 Authors: Jaroslav Nunvar Andrew M. Hogan Silvia Buroni Svetlana Savina Vadim Makarov Silvia T. Cardona Pavel Drevinek Bacteria of the Burkholderia cepacia complex (Bcc) are associated with significant decline of lung functions in cystic fibrosis patients. Bcc infections...
Sat Sep 21, 2019 03:00
Antibiotics, Vol. 8, Pages 157: Actinomycete-Derived Polyketides as a Source of Antibiotics and Lead Structures for the Development of New Antimicrobial Drugs Antibiotics doi: 10.3390/antibiotics8040157 Authors: Helene L. Robertsen Ewa M. Musiol-Kroll Actinomycetes are remarkable producers of compounds essential for human and veterinary medicine as well as for agriculture. The genomes of those microorganisms possess several sets of genes (biosynthetic gene cluster (BGC)) encoding...
Fri Sep 20, 2019 03:00
Antibiotics, Vol. 8, Pages 158: Using Colistin as a Trojan Horse: Inactivation of Gram-Negative Bacteria with Chlorophyllin Antibiotics doi: 10.3390/antibiotics8040158 Authors: Peter Richter Marcus Krüger Binod Prasad Susanne Gastiger Mona Bodenschatz Florian Wieder Andreas Burkovski Walter Geißdörfer Michael Lebert Sebastian M. Strauch Colistin (polymyxin E) is a membrane-destabilizing antibiotic used against Gram-negative bacteria. We have recently reported...
Fri Sep 20, 2019 03:00
Antibiotics, Vol. 8, Pages 156: Carbapenem-Resistant Enterobacteriaceae Posing a Dilemma in Effective Healthcare Delivery Antibiotics doi: 10.3390/antibiotics8040156 Authors: Angus Nnamdi Oli Chimaobi Johnpaul Itumo Princeston Chukwuemeka Okam Ifeanyichukwu U. Ezebialu Kenneth Nchekwube Okeke Christian Chukwuemeka Ifezulike Ifeanyi Ezeobi George Ogonna Emechebe Ugochukwu Moses Okezie Samson A. Adejumo Jude Nnaemeka Okoyeh The emergence and spread of Carbapenem-resistant...
Fri Sep 20, 2019 03:00
Antioxidants, Vol. 8, Pages 424: Protective Effect of Selected Antioxidants on Naproxen Photodegradation in Aqueous Media Antioxidants doi: 10.3390/antiox8100424 Authors: Kohei Kawabata Ayaka Takato Sayaka Oshima Shiori Akimoto Masanori Inagaki Hiroyuki Nishi A photostabilization strategy is an important aspect of quality assurance for photosensitive compounds. This study focused on the photoprotective effects of selected antioxidants including the effect of L-ascorbic...
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Antioxidants, Vol. 8, Pages 423: p53-Mediated Oxidative Stress Enhances Indirubin-3′-Monoxime-Induced Apoptosis in HCT116 Colon Cancer Cells by Upregulating Death Receptor 5 and TNF-Related Apoptosis-Inducing Ligand Expression Antioxidants doi: 10.3390/antiox8100423 Authors: Matharage Gayani Dilshara Ilandarage Menu Neelaka Molagoda Rajapaksha Gedara Prasad Tharanga Jayasooriya Yung Hyun Choi Cheol Park Kyoung Tae Lee Seungheon Lee Gi-Young Kim Indirubin-3′-monoxime...
Sun Sep 22, 2019 03:00
Antioxidants, Vol. 8, Pages 422: The Anti-Cancer Effect of Mangifera indica L. Peel Extract is Associated to γH2AX-mediated Apoptosis in Colon Cancer Cells Antioxidants doi: 10.3390/antiox8100422 Authors: Marianna Lauricella Valentina Lo Galbo Cesare Cernigliaro Antonella Maggio Antonio Palumbo Piccionello Giuseppe Calvaruso Daniela Carlisi Sonia Emanuele Michela Giuliano Antonella D’Anneo Ethanolic extracts from Mangifera indica L. have been proved to possess...
Sun Sep 22, 2019 03:00
Antioxidants, Vol. 8, Pages 421: Alpha-Glucosidase and Alpha-Amylase Inhibitory Activities of Novel Abietane Diterpenes from Salvia africana-lutea Antioxidants doi: 10.3390/antiox8100421 Authors: Etsassala Badmus Waryo Marnewick Cupido Hussein Iwuoha The re-investigation of a methanolic extract of Salvia africana-lutea collected from the Cape Floristic Region, South Africa (SA), afforded four new abietane diterpenes, namely 19-acetoxy-12-methoxycarnosic acid...
Fri Sep 20, 2019 03:00
Antioxidants, Vol. 8, Pages 420: Combined Treatment with Three Natural Antioxidants Enhances Neuroprotection in a SH-SY5Y 3D Culture Model Antioxidants doi: 10.3390/antiox8100420 Authors: Marrazzo Angeloni Hrelia Currently, the majority of cell-based studies on neurodegeneration are carried out on two-dimensional cultured cells that do not represent the cells residing in the complex microenvironment of the brain. Recent evidence has suggested that three-dimensional (3D) in vitro...
Fri Sep 20, 2019 03:00
Antioxidants, Vol. 8, Pages 419: Phenolic Compounds and Antioxidant Activities of Potato Cultivars with White, Yellow, Red and Purple Flesh Antioxidants doi: 10.3390/antiox8100419 Authors: Weidong Ru Yuehan Pang Yuanruo Gan Qin Liu Jinsong Bao The contents of total phenolics (TPC), individual phenolic acid and antioxidant activities in the free and bound fractions of potato with different flesh colors were systematically investigated. The TPC and antioxidant capacity in the...
Fri Sep 20, 2019 03:00
Arts, Vol. 8, Pages 123: Mapping the Sea on Scotland’s Peripheries Arts doi: 10.3390/arts8040123 Authors: Panneels This paper examines the use of mapping methodologies in some recent examples of contemporary art that chart the layered seascapes of the remote coastlines on North West Scotland as seen through the lens of visual culture in the Anthropocene. The art projects interrogate conflicting perspectives on landscape and nature in the North. The case studies demonstrate, both directly...
Fri Sep 20, 2019 03:00
Atmosphere, Vol. 10, Pages 572: Visualization of Climate Factors for Sports Events and Activities–The Tokyo 2020 Olympic Games Atmosphere doi: 10.3390/atmos10100572 Authors: Andreas Matzarakis Dominik Fröhlich Stéphane Bermon Paolo Emilio Adami Detailed climate information in an easily interpretable form is demanded by the general public, as well as by decision-makers on different planning levels. One example is the group of planners in the field of sports and tourism. A promising...
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Atmosphere, Vol. 10, Pages 569: A Comparison of Einstein A Coefficients for OH Rotational Temperature Measurements Using a Large Astronomical Data Set Atmosphere doi: 10.3390/atmos10100569 Authors: Murdock Hart The Einstein A coefficients are considered to be a significant source of uncertainty in the measurement of OH rotational temperatures. Using simultaneous ground and spaced-based observations of OH emission, five sets of Einstein A coefficients were examined for their...
Sun Sep 22, 2019 03:00
Atmosphere, Vol. 10, Pages 570: Comparison of NMC and Ensemble-Based Climatological Background-Error Covariances in an Operational Limited-Area Data Assimilation System Atmosphere doi: 10.3390/atmos10100570 Authors: Antonio Stanesic Kristian Horvath Endi Keresturi The evaluation of several climatological background-error covariance matrix (defined as the B matrix) estimation methods was performed using the ALADIN limited-area modeling data-assimilation system at a 4 km horizontal...
Sun Sep 22, 2019 03:00
Atmosphere, Vol. 10, Pages 571: Use of Dithiothreitol Assay to Evaluate the Oxidative Potential of Atmospheric Aerosols Atmosphere doi: 10.3390/atmos10100571 Authors: Jiang Ahmed Canchola Chen Lin Oxidative potential (OP) has been proposed as a useful descriptor for the ability of particulate matter (PM) to generate reactive oxygen species (ROS) and consequently induce oxidative stress in biological systems, which has been recognized as one of the most important mechanisms...
Sun Sep 22, 2019 03:00
Atmosphere, Vol. 10, Pages 568: New Gap-Filling Strategies for Long-Period Flux Data Gaps Using a Data-Driven Approach Atmosphere doi: 10.3390/atmos10100568 Authors: Minseok Kang Kazuhito Ichii Joon Kim Yohana M. Indrawati Juhan Park Minkyu Moon Jong-Hwan Lim Jung-Hwa Chun In the Korea Flux Monitoring Network, Haenam Farmland has the longest record of carbon/water/energy flux measurements produced using the eddy covariance (EC) technique. Unfortunately, there are...
Sun Sep 22, 2019 03:00
Atmosphere, Vol. 10, Pages 567: Modeling Climate Change Impacts on Rice Growth and Yield under Global Warming of 1.5 and 2.0 °C in the Pearl River Delta, China Atmosphere doi: 10.3390/atmos10100567 Authors: Yahui Guo Wenxiang Wu Mingzhu Du Xiaoxuan Liu Jingzhe Wang Christopher Robin Bryant In this study, the potential climate change impacts on rice growth and rice yield under 1.5 and 2.0 °C warming scenarios, respectively, are simulated using the Ceres-Rice Model...
Sat Sep 21, 2019 03:00
Atmosphere, Vol. 10, Pages 566: Fusion of High-Resolution Reflectivity for a New Array Weather Radar
Atmosphere, Vol. 10, Pages 566: Fusion of High-Resolution Reflectivity for a New Array Weather Radar Atmosphere doi: 10.3390/atmos10100566 Authors: Kai Ye Ling Yang Shuqing Ma Xiaoqiong Zhen Xingang Fan Array Weather Radar (AWR) is a novel type weather radar equipped with a distributed phased array technology. As a new instrument with new technology, the AWR offers very high spatiotemporal resolution that enables detection of the fine-scale flow field and reflectivity of...
Fri Sep 20, 2019 03:00
Atmosphere, Vol. 10, Pages 565: Aromatic Hydrocarbons in Urban and Suburban Atmospheres in Central China: Spatiotemporal Patterns, Source Implications, and Health Risk Assessment Atmosphere doi: 10.3390/atmos10100565 Authors: Pei Zeng Hai Guo Hairong Cheng Zuwu Wang Lewei Zeng Xiaopu Lyu Lingxi Zhan Zhen Yang Ambient aromatic hydrocarbons (AHs) are hazardous air pollutants and the main precursors of ozone (O3). In this study, the characteristics of ambient AHs were...
Fri Sep 20, 2019 03:00
Biology, Vol. 8, Pages 69: The Role of Lipopolysaccharide-Induced Extracellular Vesicles in Cardiac Cell Death Biology doi: 10.3390/biology8040069 Authors: Courtnee’ R. Bell Leandra B. Jones Brennetta J. Crenshaw Sanjay Kumar Glenn C. Rowe Brian Sims Gulnaz T. Javan Qiana L. Matthews Exosomes play a crucial role in the progression of infectious diseases, as exosome release and biogenesis are affected by external factors, such as pathogenic infections. Pyrogens may...
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Biomedicines, Vol. 7, Pages 73: Beyond the Biological Effect of a Chemically Characterized Poplar Propolis: Antibacterial and Antiviral Activity and Comparison with Flurbiprofen in Cytokines Release by LPS-Stimulated Human Mononuclear Cells Biomedicines doi: 10.3390/biomedicines7040073 Authors: Paolo Governa Maria Grazia Cusi Vittoria Borgonetti José Mauricio Sforcin Chiara Terrosi Giulia Baini Elisabetta Miraldi Marco Biagi Bee propolis, especially Euro-Asian poplar...
Sat Sep 21, 2019 03:00
Biomimetics, Vol. 4, Pages 65: Fuzzy Logic-Based Control for a Morphing Wing Tip Actuation System: Design, Numerical Simulation, and Wind Tunnel Experimental Testing Biomimetics doi: 10.3390/biomimetics4040065 Authors: Khan Grigorie Botez Mamou Mébarki The paper presents the design, numerical simulation, and wind tunnel experimental testing of a fuzzy logic-based control system for a new morphing wing actuation system equipped with Brushless DC (BLDC) motors, under the...
Sat Sep 21, 2019 03:00
Biomolecules, Vol. 9, Pages 521: Antifungal Agents in Agriculture: Friends and Foes of Public Health
Biomolecules, Vol. 9, Pages 521: Antifungal Agents in Agriculture: Friends and Foes of Public Health Biomolecules doi: 10.3390/biom9100521 Authors: Veronica Soares Brauer Caroline Patini Rezende Andre Moreira Pessoni Renato Graciano De Paula Kanchugarakoppal S. Rangappa Siddaiah Chandra Nayaka Vijai Kumar Gupta Fausto Almeida Fungal diseases have been underestimated worldwide but constitute a substantial threat to several plant and animal species as well as to public...
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Biomolecules, Vol. 9, Pages 520: Iso-Mukaadial Acetate from Warburgia salutaris Enhances Glucose Uptake in the L6 Rat Myoblast Cell Line Biomolecules doi: 10.3390/biom9100520 Authors: Nontokozo Z. Msomi Francis O. Shode Ofentse J. Pooe Sithandiwe Mazibuko-Mbeje Mthokozisi B. C. Simelane Diabetes mellitus (DM) is a chronic metabolic disorder which has become a major risk to the health of humankind, as its global prevalence is increasing rapidly. Currently available treatment...
Sun Sep 22, 2019 03:00
Biomolecules, Vol. 9, Pages 519: The Differential DNA Hypermethylation Patterns of microRNA-137 and microRNA-342 Locus in Early Colorectal Lesions and Tumours Biomolecules doi: 10.3390/biom9100519 Authors: Elham Kashani Mahrooyeh Hadizadeh Vahid Chaleshi Reza Mirfakhraie Chris Young Sanaz Savabkar Shiva Irani Hamid Asadzadeh Aghdaei Maziar Ashrafian Bonab Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide, representing 13% of all cancers....
Sat Sep 21, 2019 03:00
Biomolecules, Vol. 9, Pages 518: Variation in Chemical Composition and Biological Activities of Flos Chrysanthemi indici Essential Oil under Different Extraction Methods Biomolecules doi: 10.3390/biom9100518 Authors: Chang-Liang Jing Rui-Huan Huang Yan Su Yi-Qiang Li Cheng-Sheng Zhang Flos Chrysanthemi indici, an important medicinal and aromatic plant in China, is considered to have many different preservative and pharmacological properties. Considering the capability of...
Sat Sep 21, 2019 03:00
Biomolecules, Vol. 9, Pages 517: Inhibition of Ghrelin Activity by Receptor Antagonist [d-Lys-3] GHRP-6 Attenuates Alcohol-Induced Hepatic Steatosis by Regulating Hepatic Lipid Metabolism Biomolecules doi: 10.3390/biom9100517 Authors: Karuna Rasineni Jacy L. Kubik Carol A. Casey Kusum K. Kharbanda Alcoholic steatosis, characterized by an accumulation of triglycerides in hepatocytes, is one of the earliest pathological changes in the progression of alcoholic liver disease. In...
Sat Sep 21, 2019 03:00
Biomolecules, Vol. 9, Pages 516: Fish Oil, but Not Olive Oil, Ameliorates Depressive-Like Behavior and Gut Microbiota Dysbiosis in Rats under Chronic Mild Stress Biomolecules doi: 10.3390/biom9100516 Authors: Te-Hsuan Tung Yu-Tang Tung I-Hsuan Lin Chun-Kuang Shih Ngan Thi Kim Nguyen Amalina Shabrina Shih-Yi Huang Background: This study investigated the effects of fish oil and olive oil in improving dysbiosis and depressive-like symptoms. Methods and results: Male rats...
Sat Sep 21, 2019 03:00
Biomolecules, Vol. 9, Pages 515: Cost-Effective Cosmetic-Grade Hyaluronan Hydrogels for ReNcell VM Human Neural Stem Cell Culture Biomolecules doi: 10.3390/biom9100515 Authors: Ma Suh Hyaluronic acid (HA) is a polysaccharide polymer frequently used as a starting material to fabricate hydrogels, especially for recapitulating the brain’s extracellular matrix (ECM) for in vitro neural stem cell (NSC) cultures. Here, we report the successful synthesis of a methacrylated HA...
Fri Sep 20, 2019 03:00
Biomolecules, Vol. 9, Pages 514: Novel Thiazole Phenoxypyridine Derivatives Protect Maize from Residual Pesticide Injury Caused by PPO-Inhibitor Fomesafen Biomolecules doi: 10.3390/biom9100514 Authors: Zhao Yin Wang Zou Ren Gao Fu Ye The herbicide fomesafen has the advantages of low toxicity and high selectivity, and the target of this compound is protoporphyrinogen IX oxidase (PPO, EC 1.3.3.4). However, this herbicide has a long residual period and can have...
Fri Sep 20, 2019 03:00
Biomolecules, Vol. 9, Pages 513: Regulation of Membrane Calcium Transport Proteins by the Surrounding Lipid Environment Biomolecules doi: 10.3390/biom9100513 Authors: Conrard Tyteca Calcium ions (Ca2+) are major messengers in cell signaling, impacting nearly every aspect of cellular life. Those signals are generated within a wide spatial and temporal range through a large variety of Ca2+ channels, pumps, and exchangers. More and more evidences suggest that Ca2+ exchanges are regulated...
Fri Sep 20, 2019 03:00
Biomolecules, Vol. 9, Pages 511: Blockade of Intranigral and Systemic D3 Receptors Stimulates Motor Activity in the Rat Promoting a Reciprocal Interaction among Glutamate, Dopamine, and GABA Biomolecules doi: 10.3390/biom9100511 Authors: Marina Rodríguez-Sánchez Rodrigo Erick Escartín-Pérez Gerardo Leyva-Gómez José Arturo Avalos-Fuentes Francisco Javier Paz-Bermúdez Santiago Iván Loya-López Jorge Aceves David Erlij Hernán Cortés Benjamín Florán In vivo activation...
Fri Sep 20, 2019 03:00
Biomolecules, Vol. 9, Pages 512: HMGB1-triggered inflammation inhibition of notoginseng leaf triterpenes against cerebral ischemia and reperfusion injury via MAPK and NF-κB signaling pathways Biomolecules doi: 10.3390/biom9100512 Authors: Xie Zhu Dong Nan Meng Zhou Sun Sun Ischemic stroke is a clinically common cerebrovascular disease whose main risks include necrosis, apoptosis and cerebral infarction, all caused by cerebral ischemia and reperfusion (I/R)...
Fri Sep 20, 2019 03:00
Biosensors, Vol. 9, Pages 112: Viability of Neural Cells on 3D Printed Graphene Bioelectronics Biosensors doi: 10.3390/bios9040112 Authors: Guo Niaraki Asli Williams Lai Wang Montazami Hashemi Parkinson’s disease (PD) is the second most common neurodegenerative disease in the United States after Alzheimer’s disease (AD). To help understand the electrophysiology of these diseases, N27 neuronal cells have been used as an in vitro model. In this...
Fri Sep 20, 2019 03:00
Brain Sciences, Vol. 9, Pages 247: Well-Being Workshops in Eating Disorder Wards and Their Perceived Benefits to Patients and the Multi-Disciplinary Team: A Pilot Study Brain Sciences doi: 10.3390/brainsci9100247 Authors: Katherine Smith Yasemin Dandil Claire Baillie Kate Tchanturia A more holistic definition of patients’ recovery from eating disorders (EDs) highlights that well-being interventions linked to self-compassion are under-researched and under-utilised....
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Brain Sciences, Vol. 9, Pages 246: Depressive Symptoms among Economically Disadvantaged African American Older Adults in South Los Angeles Brain Sciences doi: 10.3390/brainsci9100246 Authors: Meghan C. Evans Sharon Cobb James Smith Mohsen Bazargan Shervin Assari Background: Although social, behavioral, and health factors correlate with depressive symptoms, less is known about these links among economically disadvantaged African American (AA) older adults. Objective: To study...
Sun Sep 22, 2019 03:00
Brain Sciences, Vol. 9, Pages 245: Parkinsonism with a Hint of Huntington’s from 29 CAG Repeats in HTT Brain Sciences doi: 10.3390/brainsci9100245 Authors: Sipilä JOT Huntington’s disease is caused by at least 36 cytosine-adenine-guanine (CAG) repeats in an HTT gene allele, but repeat tracts in the intermediate range (27–35 repeats) also display a subtle phenotype. This patient had a slightly elongated CAG repeat tract (29 repeats), a prominent family history of Parkinson’s...
Sun Sep 22, 2019 03:00
Brain Sciences, Vol. 9, Pages 244: C57BL/6 Substrain Differences in Pharmacological Effects after Acute and Repeated Nicotine Administration Brain Sciences doi: 10.3390/brainsci9100244 Authors: Lois S. Akinola Bryan Mckiver Wisam Toma Andy Z. X. Zhu Rachel F. Tyndale Vivek Kumar M. Imad Damaj Tobacco smoking is the major cause of disability and death in the United States and around the world. In addition, tobacco dependence and addiction express themselves as complex...
Sat Sep 21, 2019 03:00
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