The zoonotic pathogen Salmonella not only reduces the production performance in ducks, but also poses a serious threat to human health through eggs and pollutes water bodies through feces. SipC, an effector protein of type III secretion systems (T3SS) in Salmonella, mediates translocation of effectors into the eukaryotic host. However, the precise role of SipC effectors remains unknown in ducks. In this study, the SipC from duck granulosa cells (dGCs) was selected as bait, and the SipC-interacting...
Fri Sep 13, 2019 03:00
Bioacoustics is a powerful tool used for anuran species diagnoses, given that advertisement calls are signals related to specific recognition and mate attraction. Thus, call descriptions can support species taxonomy. In spite of that, call descriptions are lacking for many species, delaying advances in biodiversity research. Here, we describe the advertisement calls of 20 anuran species from the Brazilian Atlantic Forest. We accessed 50 digital recordings deposited in the Fonoteca Neotropical Jacques...
Fri Sep 13, 2019 03:00
Background The increasing demand for food production has resulted in the use of large quantities of chemical fertilizers. This has created major environmental problems, such as increased ammonia volatilization, N2O emission, and nitrogen (N) leaching from agricultural soil. In particular, the utilization rate of N fertilizer is low in subtropical southern parts of China due to high rainfall. This causes not only large financial losses in agriculture, but also serious environmental...
Fri Sep 13, 2019 03:00
Global loss of biodiversity is an ongoing process that concerns both local and global authorities. Studies of biodiversity mainly involve traditional methods using morphological characters and molecular protocols. However, conventional methods are a time consuming and resource demanding task. The development of high-throughput sequencing (HTS) techniques has reshaped the way we explore biodiversity and opened a path to new questions and novel empirical approaches. With the emergence of HTS, sequencing...
Fri Sep 13, 2019 03:00
Background Salt sensitivity of blood pressure (SSBP) is an independent risk factor for cardiovascular disease. The pathogenic mechanisms of SSBP are still uncertain. This study aimed to construct the co-regulatory network of SSBP and data mining strategy based on the competitive endogenous RNA (ceRNA) theory. Methods LncRNA and mRNA microarray was performed to screen for candidate RNAs. Four criteria were used to select...
Fri Sep 13, 2019 03:00
Summary Background Due to rising skin cancer incidence rates there is an urgent need for a quick, reliable and cost‐effective therapy. Previous studies showed that fresh tumor tissue and margins could be directly examined microscopically with high sensitivity and specificity. Objective Comparing the accuracy of rapid lump examination (RLE) for the detection of basal cell carcinoma (BCC) during micrographic surgery with formalin‐fixed paraffin‐embedded hematoxylin and eosin (HE)‐stained...
Fri Sep 13, 2019 12:03
Related ArticlesGPCRs and Insulin Receptor Signaling in Conversation: Novel Avenues for Drug Discovery. Curr Top Med Chem. 2019 Jul 12;: Authors: Gupta MK, Vasudevan NT Abstract Type 2 diabetes is a major health issue worldwide with complex metabolic and endocrine abnormalities. Hyperglycemia, defects in insulin secretion and insulin resistance are classic features of type 2 diabetes. Insulin signaling regulates metabolic homeostasis by regulating glucose...
Fri Sep 13, 2019 15:18
Related ArticlesEDITORIAL; GPCR Drug Discovery: Emerging Targets, Novel Approaches and Future Trends. Curr Top Med Chem. 2019 Aug 27;: Authors: Zhou J, Wild C PMID: 31513505 [PubMed - as supplied by publisher]
Fri Sep 13, 2019 15:18
Related ArticlesEfficacy of oral metformin in a patient with metastatic adrenocortical carcinoma: Examination of mechanisms and therapeutic implications. Rare Tumors. 2018;10:2036361317749645 Authors: Peixoto RD, Gomes LM, Sousa TT, Racy DJ, Shigenaga M, Nagourney RA Abstract Although rare, adrenocortical carcinoma is among the most common tumors found in children with Li-Fraumeni syndrome and Li-Fraumeni-like syndrome, associated with germ-line mutations...
Fri Sep 13, 2019 13:15
Related ArticlesExtraskeletal osteosarcoma: A large series treated at a single institution. Rare Tumors. 2018;10:2036361317749651 Authors: Wang H, Miao R, Jacobson A, Harmon D, Choy E, Hornicek F, Raskin K, Chebib I, DeLaney TF, Chen YE Abstract Purpose: This study is to present a large cohort of extraskeletal osteosarcoma (ESOS) and evaluate prognostic factors and treatment options. Methods: Medical records were reviewed retrospectively for 41 patients...
Fri Sep 13, 2019 13:15
Publication date: December 2019Source: Cancer Epidemiology, Volume 63Author(s): Xiao Lin, Michael S Bloom, Zhicheng Du, Yuantao HaoAbstractBackgroundForecast of disease burden in lung cancer is an important health agenda. One of the main challenges is to predict the evolution of trends in disability-adjusted life year (DALY) of lung cancer so as to anticipate the future burden and to coordinate the supply of sufficient health services and care.MethodsUsing 2004–2013 cancer registry data in Guangzhou,...
Fri Sep 13, 2019 13:15
Related ArticlesFlow Cytometry-Based Photodynamic Diagnosis with 5-Aminolevulinic Acid for the Detection of Minimal Residual Disease in Multiple Myeloma. Tohoku J Exp Med. 2019;249(1):19-28 Authors: Iwaki K, Fujiwara T, Ito T, Suzuki C, Sasaki K, Ono K, Saito K, Fukuhara N, Onishi Y, Yokoyama H, Fujimaki S, Tanaka T, Tamura H, Fujiwara M, Harigae H Abstract Multiple myeloma is the cancer of plasma cells. Along with the development of new and effective...
Fri Sep 13, 2019 13:19
Related ArticlesDeveloping a Prenatal Couple Education Program Focusing on Coparenting for Japanese Couples: A Quasi-Experimental Study. Tohoku J Exp Med. 2019;249(1):9-17 Authors: Takeishi Y, Nakamura Y, Kawajiri M, Atogami F, Yoshizawa T Abstract Having and raising children can be a source of joy for parents. However, the transition to parenthood is associated with a certain degree of strain and stress, and couple relationship quality often declines...
Fri Sep 13, 2019 13:19
Related ArticlesPlasma Free Protein S Is Correlated with Disease Activity, but not with Subclinical Atherosclerosis among Patients with Systemic Lupus Erythematosus: A Cross-Sectional Study. Tohoku J Exp Med. 2019;249(1):1-7 Authors: Jung JY, Lee SW, Kim HA, Suh CH Abstract A defect in clearance of apoptotic materials is pivotal in the pathogenesis of systemic lupus erythematosus (SLE). Protein S participates in the removal of apoptotic remnants and...
Fri Sep 13, 2019 13:19
Publication date: Available online 12 September 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Claudia Zecena Morales, Lachlan McDowell, Karolina Lisy, Amanda Piper, Michael Jefford
Fri Sep 13, 2019 13:19
Publication date: Available online 13 September 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): S.C.J. Bosma, M. Hoogstraat, F. van der Leij, M. de Maaker, J. Wesseling, E. Lips, C.E. Loo, E. Rutgers, P.H.M. Elkhuizen, H. Bartelink, M.J. van de VijverAbstractPurposeWe aimed to study radiation-induced gene expression changes and to identify differences in gene expression between patients with and without response to radiotherapy (RT) for invasive breast cancer with...
Fri Sep 13, 2019 13:19
Publication date: Available online 12 September 2019Source: Human PathologyAuthor(s): Ralph H. Hruban, David S. Klimstra, Guiseppe Zamboni, Günter KlöppelSummaryThe last fifty years have witnessed an explosion in our understanding of the pathology of pancreatic diseases. Entities known to exist 50 years ago have been defined more precisely and are now better classified. New entities, previously not recognized, have been discovered and can now be treated. Importantly, new tools have been developed...
Fri Sep 13, 2019 13:26
Related ArticlesAn Anatomic Variant of the Ansa Cervicalis Precluding Its Use as a Donor Nerve. Ann Otol Rhinol Laryngol. 2019 Sep 11;:3489419875975 Authors: Zhu A, Mohan S, Richmon JD, Jowett N Abstract BACKGROUND: The ansa cervicalis is useful for cranial nerve repair, and may be harvested without apparent morbidity. Herein we report an unusual and surgically relevant anatomic variant of the ansa cervicalis. METHODS: An adult male with left...
Fri Sep 13, 2019 13:29
Related ArticlesA Practical Mathematic Method to Predict and Manage Hypocalcemia After Parathyroidectomy and Thyroidectomy. Ann Otol Rhinol Laryngol. 2019 Sep 11;:3489419876291 Authors: Liu C, Tang L, Goel P, Chambers T, Kokot N, Sinha U, Maceri D Abstract OBJECTIVE: Prediction and early intervention for hypocalcemia following parathyroidectomy and total thyroidectomy can decrease hospital cost and prevent severe hypocalcemia-related complications. This...
Fri Sep 13, 2019 13:29
Related ArticlesAssessment of Silver-Nanoparticles-Induced Erythrocyte Cytotoxicity through Ion Transport Studies. Cell Physiol Biochem. 2019;53(3):532-549 Authors: Adragna NC, Alla PK, Pavel-Sizmore IE, Paluri ASL, Yaklic J, Lauf PK Abstract BACKGROUND/AIMS: Silver nanoparticles (AgNPs) are the most frequently used nanomaterials in industrial and biomedical applications. Their functionalization significantly impacts their properties and potential applications....
Fri Sep 13, 2019 13:35
Related Articles[Progress and controversy of full-endoscopic thoracic spine decompression]. Zhonghua Yi Xue Za Zhi. 2019 Sep 03;99(33):2561-2565 Authors: Li ZZ, Hou SX PMID: 31510712 [PubMed - in process]
Fri Sep 13, 2019 13:37
Related Articles[Current problems and challenges for percutaneous endoscopic transforaminal lumbar interbody fusion]. Zhonghua Yi Xue Za Zhi. 2019 Sep 03;99(33):2566-2568 Authors: Yang JC PMID: 31510713 [PubMed - in process]
Fri Sep 13, 2019 13:37
Related Articles[Quantitative study on the development of fetal ventricles and cisterna magna in second and third trimesters with MRI]. Zhonghua Yi Xue Za Zhi. 2019 Sep 03;99(33):2569-2574 Authors: Ma XL, Zhang GF, Wang XZ, Tian XM, Zhou Q, Shen MH, Zhong T, Ding N Abstract Objective: To analyze the changes of growth and development of normal fetal ventricles and cisterna magna with gestational age(GA) and the correlation with fetal gender in the second...
Fri Sep 13, 2019 13:37
Related Articles[Contrast-enhanced CT and texture analysis of mass-forming pancreatitis and cancer in the pancreatic head]. Zhonghua Yi Xue Za Zhi. 2019 Sep 03;99(33):2575-2580 Authors: Zhang JJ, Li QZ, Wang JH, Chen X, Ren S, Ye DD, Zhang HF, Wang ZQ Abstract Objective: To explore the value of contrast-enhanced CT combined with texture analysis in differentiating pancreatic cancer from mass-forming pancreatitis in pancreatic head. Methods: A retrospective...
Fri Sep 13, 2019 13:37
Related Articles[Clinical application value of prognosis of nutrition index and apparent diffusion coefficient in patient with hepatocellular carcinoma underwent transarterial chemoembolization]. Zhonghua Yi Xue Za Zhi. 2019 Sep 03;99(33):2581-2585 Authors: Sun WH, Zhang AD, Li W Abstract Objective: To explore clinical application value of prognostic nutrition index(PNI) and apparent diffusion coefficient(ADC) in treating hepatic arterial chemoembolization...
Fri Sep 13, 2019 13:37
Related Articles[Preliminary application value of ultrasound contrast agent with enteral nutritional suspension as mixed medium in locating indwelling nasointestinal tube in critically ill patients]. Zhonghua Yi Xue Za Zhi. 2019 Sep 03;99(33):2586-2591 Authors: Ye RZ, Peng CZ, Sun RH, Liu JQ, Yang XH, Du LP, Wu WH Abstract Objective: To evaluate the value of ultrasound contrast agent with enteral nutrition suspension as mixed medium in locating indwelling...
Fri Sep 13, 2019 13:37
Related Articles[Clinical analysis of 36 cases of idiopathic intracranial hypertension complicated with iron deficiency anemia]. Zhonghua Yi Xue Za Zhi. 2019 Sep 03;99(33):2592-2596 Authors: Meng C, Lai CT, Jing Y, Jiang HQ, Sun HL, Ma ZH, Wang JW Abstract Objective: To investigate the clinical features, imaging findings and prognosis of idiopathic intracranial hypertension (IIH) patients complicated with iron deficiency anemia (IDA). Methods: A total...
Fri Sep 13, 2019 13:37
Related Articles[Application of complete endoscopic technique in microvascular decompression related tovertebrobasilar artery compression]. Zhonghua Yi Xue Za Zhi. 2019 Sep 03;99(33):2597-2601 Authors: Zhu GT, Hu ZQ, Huang H, Dai B, Guan F, Xiao ZY, Mao BB Abstract Objective: To study the operative method, special technique and curative effect of complete neuroendoscopic microvascular decompression(MVD) related to vertebrobasilar artery compression....
Fri Sep 13, 2019 13:37
Related Articles[The effect of three trigger methodson pregnancy outcome of intrauterine insemination]. Zhonghua Yi Xue Za Zhi. 2019 Sep 03;99(33):2602-2605 Authors: Li M, Lü Y, Zhu YM Abstract Objective: To analysepregnancy outcome of intrauterine insemination(IUI) after three different trigger methods. Methods: A retrospective study was designed, included 341 couples seeking for their first or second IUI cycle from 2016.7 to 2018.6 in women's hospital,...
Fri Sep 13, 2019 13:37
Related Articles[Effect of intravenous granisetron combined and acupuncture point injection at PC6(Neiguan) with 0.9% sodium chlorideon postoperative nausea and vomiting after gynecological laparoscopy]. Zhonghua Yi Xue Za Zhi. 2019 Sep 03;99(33):2606-2610 Authors: Yu Y, Fan H, Cheng Y, Sun JL Abstract Objective: To observe the effects of intravenous granisetron and acupuncture point injection at PC6(Neiguan) with 0.9% sodium chloride on postoperative...
Fri Sep 13, 2019 13:37
Related Articles[Analysis of risk factors associated central venous catheter-related thrombosis in patients undergoing abdominal operation]. Zhonghua Yi Xue Za Zhi. 2019 Sep 03;99(33):2611-2614 Authors: Zhu XG, Zheng XY, Ma WX Abstract Objective: To analyze the risk factors of catheter-related right jugular venous thrombosis in patients undergoing abdominal surgery. Methods: A total of 125 patients (18-90 years, ASA Ⅰ-Ⅲ) scheduled for abdominal surgery...
Fri Sep 13, 2019 13:37
Related Articles[Clinical analysis of five cases of autism spectrum disorder complicated with epilepsy with chromosome copy number variation]. Zhonghua Yi Xue Za Zhi. 2019 Sep 03;99(33):2615-2618 Authors: Li MY, Ye J, Huang ZY, Lin YC, Liu AH, Li LP, Chen J, Wang YP Abstract Objective: To explore the clinical features and genetic causes of autism spectrum disorder (ASD) patients with epilepsy. Methods: The clinical data of five patients with ASD and...
Fri Sep 13, 2019 13:37
Publication date: Available online 12 September 2019Source: Critical Reviews in Oncology/HematologyAuthor(s): Cristina Picardi, Francesca Caparroti, Massimo Di Maio, Filip Kaššák, Giuseppe Luigi Banna, Alfredo AddeoAbstractExtensive disease Small cell lung cancer (ED-SCLC) represents a very aggressive malignancy in which brain metastases (BM) are quite common. Clinical trials on prophylactic cranial irradiation (PCI) have showed a clear decrease in the risk of developing BM but conflicting results...
Fri Sep 13, 2019 13:37
Publication date: October 2019Source: Critical Reviews in Oncology/Hematology, Volume 142Author(s):
Fri Sep 13, 2019 13:37
OBJECTIVE: Our purpose was to compare quantitative CT-derived changes in lung fibrosis with pulmonary function, including DLCO, in human subjects with idiopathic pulmonary fibrosis who received an injection of one of two different intravenous doses of human bone-marrow-derived mesenchymal stem cells. PATIENTS AND METHODS: Two three-subject cohorts from the AETHER trial (Allogeneic Human Cells in subjects with Idiopathic Pulmonary Fibrosis via Intravenous Delivery) underwent high-resolution CT and...
Fri Sep 13, 2019 13:44
OBJECTIVE: Acute respiratory distress syndrome (ARDS) threatens humans’ health worldwide, causing huge labor and economic cost investment. This study aims to explore whether mesenchymal stem cells (MSCs) affect RDS in newborn swines via the Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathway by the establishment of the model of the disease. MATERIALS AND METHODS: The phosphorylation of the JAK-STAT signal transduction proteins was first detected via Western...
Fri Sep 13, 2019 13:44
OBJECTIVE: To explore the correlation of the suppressor of cytokine signaling 3 (SOCS3) gene polymorphism with childhood asthma. PATIENTS AND METHODS: A total of 204 asthma children (observation group) and 235 healthy children (control group) were enrolled. General clinical information of enrolled subjects was collected. Inflammatory factors and pulmonary function test indexes in each subject were examined. Moreover, the polymorphism of SOCS3 gene rs9914220 was detected with the TaqMan-MGB probe....
Fri Sep 13, 2019 13:44
OBJECTIVE: To explore the correlation of the lymphotoxin alpha (LTα) and nicotinamide adenine dinucleotide phosphate quinone oxidoreductase 1 (NQO1) gene polymorphisms with childhood asthma. PATIENTS AND METHODS: A total of 102 asthma children (observation group) and 80 healthy children (control group) were enrolled. The information was collected via questionnaires and the polymorphisms of LTα rs2844484 and NQO1 rs2917666 were examined with the TaqMan-MGB probe. RESULTS: Observation group had higher...
Fri Sep 13, 2019 13:44
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