Objectives There have been few studies regarding the use of a picosecond‐domain laser for acne scars in Asians. This prospective study evaluated the efficacy and safety of a high‐energy 1,064 nm Nd:YAG picosecond‐domain laser for ablation and resurfacing of facial acne scars in Asians. Methods Subjects were treated with a 1,064 nm picosecond laser (8 mm spot, 0.7–1.0 J/cm2, 5 Hz) every 4 weeks for three sessions. Two blinded dermatologists evaluated the pre‐ and 3‐month post‐treatment images...
Wed Sep 04, 2019 14:37
Background and Objectives Dysregulated inflammation is one of the major contributing factors for the prevalence of non‐healing chronic wound in immunosuppressed subjects. Photobiomodulation (PBM) has emerged as a potential non‐thermal, light‐based therapeutic healing intervention for the treatment of impaired wounds. Study Design/Materials and Methods The present study delineates the underlying molecular mechanisms of PBM 810 nm laser‐induced full‐thickness cutaneous wound repair in immunosuppressed...
Wed Sep 04, 2019 14:37
Osteoporosis is a skeletal disorder that compromises bone resistance and its diagnosis is usually performed using dual energy X‐ray absorptiometry. Thus, the search for efficient diagnostic methods that do not involve the emission of ionizing radiation is necessary. This study proposed to use the Optical Coherence Tomography (OCT) to evaluate osteoporosis in alveolar bone. Osteoporosis lesions is simulated in vitro in porcine bones, and imaging is performed by OCT and micro‐computed tomography (micro‐CT)....
Wed Sep 04, 2019 19:16
Abstract Skin elasticity has been regarded as one of the main indicators of skin condition. Current measurement devices for skin elasticity are mostly expensive for home‐use and should contact the skin surface. As a first step to develop improved methods, we focus on the relation between skin elasticity and the entropy of skin images. Reduced skin elasticity causes wrinkles. It spreads frequency components and increases their randomness in the frequency domain. The randomness is quantified as entropy,...
Wed Sep 04, 2019 19:14
Endocrine therapy resistance in breast cancer is a major obstacle in the treatment of patients with estrogen receptor‐positive (ER+) tumors. Herein, we demonstrate the feasibility of longitudinal, non‐invasive, and semi‐quantitative in vivo molecular imaging of resistance to three endocrine therapies by using an inducible fluorescence labelled shRNA system in orthotopic mice xenograft tumors. We employed a dual fluorescent doxycycline (Dox)‐regulated lentiviral inducer system to transfect ER+ MCF‐7L...
Tue Sep 03, 2019 20:44
Abstract We present a first in vivo application of phase Dual‐Slopes (DSϕ), measured with Frequency‐Domain Near‐InfraRed Spectroscopy (FD NIRS) on four healthy human subjects, to demonstrate their enhanced sensitivity to cerebral hemodynamics. During Arterial Blood Pressure (ABP) oscillations elicited at a frequency of 0.1 Hz, we compare three different ways to analyze either Intensity (I) or phase (ϕ) data collected on the subject's forehead at multiple source‐detector distances: Single‐Distance...
Tue Sep 03, 2019 19:28
Thulium Laser‐Assisted Versus Conventional Laparoscopic Partial Nephrectomy for the Small Renal Mass
Background and Objectives Laparoscopic partial nephrectomy (LPN) has gained acceptance as a minimally invasive treatment option for small renal masses (SRMs). Laser‐assisted LPN (LLPN) provided a bloodless tumor excision without renal artery clamping owing to the excellent coagulative and hemostatic properties of the lasers. The primary aim of this study is to evaluate the technical feasibility and outcomes of 2‐μm continuous thulium LLPN and conventional LPN (CLPN) in the treatment of patients...
Tue Sep 03, 2019 19:13
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