IJMS, Vol. 20, Pages 4349: Inhibition of Mitochondrial Complex I Impairs Release of α-Galactosidase by Jurkat Cells International Journal of Molecular Sciences doi: 10.3390/ijms20184349 Authors: Jonathan R. A. Lambert Steven J. Howe Ahad A. Rahim Derek G. Burke Simon J. R. Heales Fabry disease (FD) is caused by mutations in the GLA gene that encodes lysosomal α-galactosidase-A (α-gal-A). A number of pathogenic mechanisms have been proposed and these include...
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IJMS, Vol. 20, Pages 4350: Different Original and Biosimilar TNF Inhibitors Similarly Reduce Joint Destruction in Rheumatoid Arthritis—A Network Meta-Analysis of 36 Randomized Controlled Trials International Journal of Molecular Sciences doi: 10.3390/ijms20184350 Authors: Niels Graudal Benjamin Skov Kaas-Hansen Louise Guski Thorbjørn Hubeck-Graudal Nicky J. Welton Gesche Jürgens The effect of five approved tumour necrosis factor inhibitors (TNFi: infliximab, etanercept,...
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Molecules, Vol. 24, Pages 3223: Ionic Liquids Enhanced Alkynyl Schiff Bases Derivatives of Fipronil Synthesis and Their Cytotoxicity Studies Molecules doi: 10.3390/molecules24183223 Authors: Liu Huang Chen Li Yan Jin Xu To obtain highly selective toxic derivatives of fipronil, a series of Schiff bases with an alkynyl group (3a–3k) were designed and synthesized from 4-ethynylbenzaldehyde (2) and 4-substituted 5-amino-N-arylpyrazole (1a–1k)...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3220: Quality Evaluation of Ophiopogonis Radix from Two Different Producing Areas Molecules doi: 10.3390/molecules24183220 Authors: Mengxia Tan Jiali Chen Chengcheng Wang Lisi Zou Shuyu Chen Jingjing Shi Yuqi Mei Lifang Wei Xunhong Liu Ophiopogonis Radix, also known as Mai-dong in Chinese, was a commonly used traditional Chinese medicine (TCM) and functional health food. Two products of Ophiopogonis Radix are largely produced in the Sichuan...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3221: Osteopathic Manipulation Treatment Improves Cerebro–splanchnic Oximetry in Late Preterm Infants Molecules doi: 10.3390/molecules24183221 Authors: Benedetta Marinelli Francesca Pluchinotta Vincenzo Cozzolino Gina Barlafante Maria Chiara Strozzi Eleonora Marinelli Simone Franchini Diego Gazzolo Background: To evaluate the effectiveness/side-effects of osteopathic manipulation treatment (OMT) performed on the 7th post-natal day, on cerebro–splanchnic...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3222: Fluorine-Substituted Arylphosphine for an NHC-Ni(I) System, Air-Stable in a Solid State but Catalytically Active in Solution Molecules doi: 10.3390/molecules24183222 Authors: Matsubara Fujii Hosokawa Inatomi Yamada Koga Monovalent NHC-nickel complexes bearing triarylphosphine, in which fluorine is incorporated onto the aryl groups, have been synthesized. Tris(3,5-di(trifluoromethyl)-phenyl)phosphine efficiently gave a monovalent nickel...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3219: Identification of Passion Fruit Oil Adulteration by Chemometric Analysis of FTIR Spectra Molecules doi: 10.3390/molecules24183219 Authors: Kiefer Lampe Nicoli Lucarini Durazzo Passion fruit oil is a high-value product with applications in the food and cosmetic sectors. It is frequently diluted with sunflower oil. Sunflower oil is also a potential adulterant as its addition does not notably alter the appearance of the passion fruit oil....
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3224: A Self-Healing and Shape Memory Polymer that Functions at Body Temperature Molecules doi: 10.3390/molecules24183224 Authors: Hui-Ying Lai Hong-Qin Wang Jian-Cheng Lai Cheng-Hui Li Dual-functional polymeric system combining shape memory with self-healing properties has attracted increasingly interests of researchers, as both of these properties are intelligent and promising characteristics. Moreover, shape memory polymer that functions at human...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3218: New Isoflavanes from Spatholobus suberectus and Their Cytotoxicity against Human Breast Cancer Cell Lines Molecules doi: 10.3390/molecules24183218 Authors: Fu Peng Huan Zhu Chun-Wang Meng Yan-Rui Ren Ou Dai Liang Xiong The rattans of Spatholobus suberectus Dunn are a traditional Chinese medicine activating blood circulation and removing stasis. They have often been used for the traditional Chinese medicinal treatment of breast cancer in...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3217: Moringin Pretreatment Inhibits the Expression of Genes Involved in Mitophagy in the Stem Cell of the Human Periodontal Ligament Molecules doi: 10.3390/molecules24183217 Authors: Luigi Chiricosta Agnese Gugliandolo Francesca Diomede Jacopo Pizzicannella Oriana Trubiani Renato Iori Giuseppe Tardiolo Simone Guarnieri Placido Bramanti Emanuela Mazzon Moringin [4-(α-L-rhamnosyloxy) benzyl isothiocyanate] is an isothiocyanate...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3215: Molecular Dynamics Gives New Insights into the Glucose Tolerance and Inhibition Mechanisms on β-Glucosidases Molecules doi: 10.3390/molecules24183215 Authors: Leon Sulfierry Corrêa Costa Diego César Batista Mariano Rafael Eduardo Oliveira Rocha Johannes Kraml Carlos Henrique da Silveira Klaus Roman Liedl Raquel Cardoso de Melo-Minardi Leonardo Henrique Franca de Lima β-Glucosidases are enzymes with high importance for many...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3216: Leishmania mexicana Trypanothione Reductase Inhibitors: Computational and Biological Studies Molecules doi: 10.3390/molecules24183216 Authors: Félix Matadamas-Martínez Alicia Hernández-Campos Alfredo Téllez-Valencia Alejandra Vázquez-Raygoza Sandra Comparán-Alarcón Lilián Yépez-Mulia Rafael Castillo Leishmanicidal drugs have many side effects, and drug resistance to all of them has been documented. Therefore, the development of new drugs...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3213: Comparative Theoretical Studies on a Series of Novel Energetic Salts Composed of 4,8-Dihydrodifurazano[3,4-b,e]pyrazine-based Anions and Ammonium-based Cations Molecules doi: 10.3390/molecules24183213 Authors: Binghui Duan Ning Liu Bozhou Wang Xianming Lu Hongchang Mo 4,8-Dihydrodifurazano[3,4-b,e]pyrazine (DFP) is one kind of parent compound for the synthesis of various promising difurazanopyrazine derivatives. In this paper, eleven series...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3214: Sex Differences in Cancer Immunotherapy Efficacy, Biomarkers, and Therapeutic Strategy Molecules doi: 10.3390/molecules24183214 Authors: Shixiang Wang Li An Cowley Xue-Song Liu Sex differences in innate and adaptive immune responses are known, and women generally mount a stronger immune response than men. Cancer immunotherapy, represented by immune checkpoint inhibitors (ICIs), has revolutionized the treatment of cancer, and sex differences in cancer...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3212: The Profile of Carotenoids and Other Bioactive Molecules in Various Pumpkin Fruits (Cucurbita maxima Duchesne) Cultivars Molecules doi: 10.3390/molecules24183212 Authors: Bartosz Kulczyński Anna Gramza-Michałowska Bioactive compounds are significant to human nutrition. They are beneficial to health as they inhibit the development of numerous diseases of affluence. Scientists continuously search for natural sources of these components. At present, the...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3211: Physicochemical Aspects and Sensory Profiles as Various Potential Factors for Comprehensive Quality Assessment of Nü-Er-Cha Produced from Rhamnus heterophylla Oliv. Molecules doi: 10.3390/molecules24183211 Authors: Le Wang Shusheng Fan Xiaoping Wang Xiuhuan Wang Xin Yan Dongjie Shan Wuqing Xiao Jiamu Ma Yanran Wang Xiao Li Xiao Xu Gaimei She Nü-Er-Cha, produced from the leaves of Rhamnus heterophylla Oliv., is...
Wed Sep 04, 2019 03:00
Molecules, Vol. 24, Pages 3210: Multi-Armed 1,2,3-Selenadiazole and 1,2,3-Thiadiazole Benzene Derivatives as Novel Glyoxalase-I Inhibitors Molecules doi: 10.3390/molecules24183210 Authors: Qosay A. Al-Balas Mousa L. Al-Smadi Mohammad A. Hassan Ghazi A. Al Jabal Ammar M. Almaaytah Karem H. Alzoubi Glyoxalase-I (Glo-I) enzyme was established to be a valid target for anticancer drug design. It performs the essential detoxification step of harmful byproducts, especially methylglyoxal....
Wed Sep 04, 2019 03:00
Nanomaterials, Vol. 9, Pages 1256: Flower-Like MoSe2/MoO2 Composite with High Capacity and Long-Term Stability for Lithium-Ion Battery Nanomaterials doi: 10.3390/nano9091256 Authors: Qiuyan Hao Guoliang Cui Yan Zhao Zhumabay Bakenov A simple method is developed for the preparation of MoSe2/MoO2 composite with a flower-like structure for high-performance lithium-ion batteries (LIBs). MoSe2 could lead to fast and facile movement of Li+ due to its larger interlayer spacing. Meanwhile,...
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Nanomaterials, Vol. 9, Pages 1255: Synthesis, Characterization and Dye Removal Behavior of Core–Shell–Shell Fe3O4/Ag/Polyoxometalates Ternary Nanocomposites Nanomaterials doi: 10.3390/nano9091255 Authors: Shixia Zhan Chunyan Li Heyun Tian Chenguang Ma Hongling Liu Jie Luo Mingxue Li The ternary nanocomposites Fe3O4/Ag/polyoxometalates (Fe3O4/Ag/POMs) with core–shell–core nanostructure were synthesized by coating [Cu(C6H6N2O)2(H2O)]H2[Cu(C6H6N2O)2(P2Mo5O23)]·4H2O...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2109: Low Serum Vitamin D Concentrations Are Associated with Insulin Resistance in Mexican Children and Adolescents Nutrients doi: 10.3390/nu11092109 Authors: Edgar Denova-Gutiérrez Paloma Muñoz-Aguirre Desiree López Mario Flores Mara Medeiros Natalia Tamborrel Patricia Clark Previous studies in the Mexican adult population have suggested a relationship between low levels of serum concentrations of serum vitamin D with impaired glucose tolerance,...
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Nutrients, Vol. 11, Pages 2108: A Randomized, Placebo-Controlled, Double-Blind Crossover Study to Assess a Unique Phytosterol Ester Formulation in Lowering LDL Cholesterol Utilizing a Novel Virtual Tracking Tool Nutrients doi: 10.3390/nu11092108 Authors: Ashley Reaver Susan Hewlings Kenneth Westerman Gil Blander Thorsten Schmeller Marianne Heer Dietrich Rein Elevated blood concentration of low-density lipoprotein cholesterol (LDLc) is a primary risk factor for developing...
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Nutrients, Vol. 11, Pages 2107: Dietary Anthocyanins and Human Health Nutrients doi: 10.3390/nu11092107 Authors: Christopher N. Blesso Anthocyanins may contribute to the inverse relationship between fruit and vegetable intake and chronic disease. Anthocyanins are pigments found in plant structures that consist of an anthocyanidin (aglycone) attached to sugar moieties. Anthocyanins may be beneficial for health through effects on cellular antioxidant status and inflammation; however, their...
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Nutrients, Vol. 11, Pages 2106: Correction: Nguyen et al. “Monobutyrin Reduces Liver Cholesterol and Improves Intestinal Barrier Function in Rats Fed High-Fat Diets” Nutrients 2019, 11, 308 Nutrients doi: 10.3390/nu11092106 Authors: Thao Duy Nguyen Olena Prykhodko Frida F. Hållenius Margareta Nyman The authors wish to make a correction to the published version of their paper [...]
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2104: Coffee and Endothelial Function: A Coffee Paradox? Nutrients doi: 10.3390/nu11092104 Authors: Higashi Coffee is a popular beverage throughout the world. Coffee contains various chemical compounds (e.g., caffeine, chlorogenic acids, hydroxyhydroquinone, kahweol, cafestol, and complex chemical mixtures). Caffeine is also the most widely consumed pharmacological substance in the world and is included in various beverages (e.g., coffee, tea, soft drinks,...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2105: Effect of Bread Structure and In Vitro Oral Processing Methods in Bolus Disintegration and Glycemic Index Nutrients doi: 10.3390/nu11092105 Authors: Aleixandre Benavent-Gil Rosell The growing interest in controlling the glycemic index of starchy-rich food has encouraged research about the role of the physical structure of food. The aim of this research was to understand the impact of the structure and the in vitro oral processing methods on bolus...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2103: Effects of Vitamin C on Organ Function in Cardiac Surgery Patients: A Systematic Review and Meta-Analysis Nutrients doi: 10.3390/nu11092103 Authors: Aileen Hill Kai C. Clasen Sebastian Wendt Ádám G. Majoros Christian Stoppe Neill K. J. Adhikari Daren K. Heyland Carina Benstoem Background: Cardiac surgery is associated with oxidative stress and systemic inflammation, which both contribute to postoperative organ dysfunction. Vitamin...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2101: Selenium, Selenoproteins and Viral Infection Nutrients doi: 10.3390/nu11092101 Authors: Olivia M. Guillin Caroline Vindry Théophile Ohlmann Laurent Chavatte Reactive oxygen species (ROS) are frequently produced during viral infections. Generation of these ROS can be both beneficial and detrimental for many cellular functions. When overwhelming the antioxidant defense system, the excess of ROS induces oxidative stress. Viral infections lead to...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2099: Regulation of the Metal Transporters ZIP14 and ZnT10 by Manganese Intake in Mice Nutrients doi: 10.3390/nu11092099 Authors: Danielle M. Felber Yuze Wu Ningning Zhao The metal transporters ZIP14 and ZnT10 play key physiological roles in maintaining manganese (Mn) homeostasis. However, in vivo regulation of these two transporters by Mn is not understood. Here, we examined how dietary Mn intake regulates ZIP14 and ZnT10 by feeding mice a low-Mn diet,...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2100: Obesity Stigma: Is the ‘Food Addiction’ Label Feeding the Problem? Nutrients doi: 10.3390/nu11092100 Authors: Helen K. Ruddock Michael Orwin Emma J. Boyland Elizabeth H. Evans Charlotte A. Hardman Obesity is often attributed to an addiction to high-calorie foods. However, the effect of “food addiction” explanations on weight-related stigma remains unclear. In two online studies, participants (n = 439, n = 523, respectively,...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2098: P-Glycoprotein 1 Affects Chemoactivities of Resveratrol against Human Colorectal Cancer Cells Nutrients doi: 10.3390/nu11092098 Authors: Virginie Aires Didier J Colin Agnès Doreau Attilio Di Pietro Jean-Marie Heydel Yves Artur Norbert Latruffe Dominique Delmas Resveratrol has been proposed to prevent tumor growth and the different steps of carcinogenesis; nevertheless, these biological effects are sometimes discordant between different...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2102: Vitamin C and Neutrophil Function: Findings from Randomized Controlled Trials Nutrients doi: 10.3390/nu11092102 Authors: Mikee Liugan Anitra C. Carr Vitamin C is known to support immune function and is accumulated by neutrophils to millimolar intracellular concentrations suggesting an important role for the vitamin in these cells. In this review, the effects of vitamin C, as a mono- or multi-supplement therapy, on neutrophil function were assessed by...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2095: Milk and Meat Allergens from Bos taurus β-Lactoglobulin, α-Casein, and Bovine Serum Albumin: An In-Vivo Study of the Immune Response in Mice Nutrients doi: 10.3390/nu11092095 Authors: Ewa Fuc Dagmara Złotkowska Barbara Wróblewska The mechanism of food allergy may vary. This study aimed to compare the effects of milk, yogurt, or beef meat supplementation on humoral and cellular immune responses in a mice model. Mice were divided into four groups:...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2096: MTA1-Dependent Anticancer Activity of Gnetin C in Prostate Cancer Nutrients doi: 10.3390/nu11092096 Authors: Avinash Kumar Kshiti Dholakia Gabriela Sikorska Luis A. Martinez Anait S. Levenson The overexpression of metastasis-associated protein 1 (MTA1) in prostate cancer (PCa) contributes to tumor aggressiveness and metastasis. We have reported the inhibition of MTA1 by resveratrol and its potent analog pterostilbene in vitro and in vivo. We...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2097: The Relationship of Obesity, Nutritional Status and Muscle Wasting in Patients Assessed for Liver Transplantation Nutrients doi: 10.3390/nu11092097 Authors: Helen Vidot Katharine Kline Robert Cheng Liam Finegan Amelia Lin Elise Kempler Simone I. Strasser David Geoffrey Bowen Geoffrey William McCaughan Sharon Carey Margaret Allman-Farinelli Nicholas Adam Shackel Introduction: Obesity co-exists with malnutrition and muscle...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2093: Asymptomatic Helicobacter Pylori Infection in Preschool Children and Young Women Does Not Predict Iron Bioavailability from Iron-Fortified Foods Nutrients doi: 10.3390/nu11092093 Authors: Simone Buerkli Ndèye Fatou Ndiaye Colin I. Cercamondi Isabelle Herter-Aeberli Diego Moretti Michael B. Zimmermann Helicobacter pylori infection is common in low-income countries. It has been associated with iron deficiency and reduced efficacy of iron supplementation....
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2094: Native Whey Induces Similar Adaptation to Strength Training as Milk, despite Higher Levels of Leucine, in Elderly Individuals Nutrients doi: 10.3390/nu11092094 Authors: Håvard Hamarsland Mathias K. Johansen Fridtjof Seeberg Marie Brochmann Ina Garthe Haakon B. Benestad Truls Raastad Background: Large amounts of protein (40 g) or supplementing suboptimal servings of protein with leucine are able to overcome the anabolic resistance in elderly...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2091: Whey Protein Combined with Low Dietary Fiber Improves Lipid Profile in Subjects with Abdominal Obesity: A Randomized, Controlled Trial Nutrients doi: 10.3390/nu11092091 Authors: Elin Rakvaag Rasmus Fuglsang-Nielsen Knud Erik Bach Knudsen Rikard Landberg Astrid Johannesson Hjelholt Esben Søndergaard Kjeld Hermansen Søren Gregersen Abdominal obesity is associated with elevated postprandial triglycerides (TG), an independent risk factor...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2090: Oxidative Stress in Cardiovascular Diseases: Still a Therapeutic Target? Nutrients doi: 10.3390/nu11092090 Authors: Thomas Senoner Wolfgang Dichtl Cardiovascular diseases (CVD) are complex entities with heterogenous pathophysiologic mechanisms and increased oxidative stress has been viewed as one of the potential common etiologies. A fine balance between the presence of reactive oxygen species (ROS) and antioxidants is essential for the proper normal...
Wed Sep 04, 2019 03:00
Nutrients, Vol. 11, Pages 2088: A Multi-Year Examination of Gardening Experience and Fruit and Vegetable Intake During College Nutrients doi: 10.3390/nu11092088 Authors: Daniel Staub Sarah E. Colby Melissa D. Olfert Kendra Kattelmann Wenjun Zhou Tanya M. Horacek Geoffrey W. Greene Ivana Radosavljevic Lisa Franzen-Castle Anne E. Mathews Gardening has been positively associated with fruit and vegetable (FV) consumption based on short-term studies among children,...
Wed Sep 04, 2019 03:00
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