Publication date: September–October 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 5Author(s): Felipe Couñago, Ana Aurora Díaz Gavela, Gemma Sancho, Irene Ortiz, Francisco José Marcos, Manuel Recio, Julio Fernández, Raquel Cano, Mar Jiménez, Israel J. Thuissard, David Sanz-Rosa, Juan Castro Nováis, Eduardo Pardo, Yolanda Molina, Hugo Pérez García, Elia del CerroAbstractAimTo analyse the efficacy and toxicity of postprostatectomy SRT in patients with a BCR evaluated...
Thu Sep 12, 2019 16:15
Publication date: September–October 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 5Author(s):
Thu Sep 12, 2019 16:15
Publication date: September–October 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 5Author(s): Zefiryn Cybulski, Bartosz Urbański, Alicja Grabiec, Zofia Talaga, Michał Pawlak, Żaneta Wareńczak-Florczak, Andrzej RoszakAbstractAimThe main goal of this investigation was to evaluate the influence of positive beta haemolytic streptococci culture from the genital tract on patients receiving radiation therapy who suffer from cervical cancer. The other aim was to observe radiation...
Thu Sep 12, 2019 16:15
Publication date: September–October 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 5Author(s): Dorota Księżniak-Baran, Sławomir Blamek, Agata Roch-Zniszczoł, Wojciech Osewski, Maja JędrzejewskaAbstractFifty-three-year-old male suffering from a presumptive non-functioning pituitary adenoma was qualified for stereotactic radiosurgery in our institution. Two attempts of surgical treatment were taken three months before radiotherapy. Excessive bleeding did not allow to...
Thu Sep 12, 2019 16:15
Publication date: September–October 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 5Author(s): Oluwaseyi Michael Oderinde, Freek du PlessisAbstractAimThis study focused on evaluating the sensitivity of integral quality monitoring (IQM®) system and MatriXX detectors. These two detectors are recommended for radiotherapy pre-treatment quality assurance (QA).BackgroundIQM is a large wedged-shaped ionisation chamber mounted to the linear accelerator (linac) head in practice....
Thu Sep 12, 2019 16:15
Publication date: September–October 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 5Author(s): Niyas Puzhakkal, Abdullah Kallikuzhiyil Kochunny, Dinesh Makuny, Arun Krishnan M.P, Ranjith C. Poyil, Vysakh RaveendranAbstractAimThe aim of this study is to commission and validate Dolphin-Compass dosimetry as a patient-specific Quality Assurance (QA) device.BackgroundThe advancement of radiation therapy in terms of highly conformal delivery techniques demands a novel method...
Thu Sep 12, 2019 16:15
Publication date: September–October 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 5Author(s): Daisuke Kawahara, Shuichi Ozawa, Kazushi Yokomachi, Toru Higaki, Takehiro Shiinoki, Yoshimi Ohno, Yuji Murakami, Kazuo Awai, Yasushi NagataAbstractObjectivesThe aim of the current study is to evaluate the accuracy and the precision of raw-data-based relative electron density (REDraw) and the calibration-based RED (REDcal) at a range of low-RED to high-RED for tissue-equivalent...
Thu Sep 12, 2019 16:15
Publication date: September–October 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 5Author(s): P. Appendino, F. Della Ferrera, D. Nassisi, G. Blandino, E. Gino, S.D. Solla, M.G. Ruo ReddaAbstractAimTo evaluate the dose sparing efficacy of intraoral customized stents in combination with IGRT/VMAT in Head & Neck cancer patients.BackgroundDespite advances in high-dose conformal radiotherapy (RT) techniques, adverse effects (such as oral mucositis) during and after...
Thu Sep 12, 2019 16:15
Colon cancer is the second leading cancer worldwide. Recurrent disease and chemotherapeutic drug resistance are very common in the advanced stage of colon cancer. ATP-citrate lyase (ACLY), the first-step rate-...
Thu Sep 12, 2019 03:00
Background. Calreticulin has been identified to play a critical role in innate and adaptive immune responses. However, little is known about the role of calreticulin in sepsis with a characteristic of immune disorder. This study was aimed at investigating whether plasma calreticulin level increases in sepsis and its association with sepsis severity. Methods. This retrospective analysis evaluated sepsis patients who were admitted to the intensive care unit (ICU). Healthy subjects were also included...
Thu Sep 12, 2019 13:05
Purpose. The study is aimed at identifying echocardiographic and circulating biomarkers as well as hemodynamic indices of embolic stroke of undetermined etiology (ESUS) in patients aged
Thu Sep 12, 2019 13:05
Background. The role of the NFKB1 gene rs28362491 polymorphism and NFKBIA gene rs2233406 polymorphism in the development of head and neck cancer (HNC) remains controversial. This meta-analysis was performed to assess the relationship between the gene polymorphisms and HNC quantitatively. Methods. PubMed, Embase, Web of Science, WanFang Data, and China National Knowledge databases were used to search for eligible articles. The relationship was evaluated by STATA 11.0. Results. Eight eligible articles...
Thu Sep 12, 2019 14:05
Thu Sep 12, 2019 16:05
Extracellular vesicles are membrane‐bound structures released from cells into the plasma or stroma. Extracellular vesicles are thought to contain chemical messengers and have a signalling function. The two main classes of extracellular vesicle are exosomes and microvesicles, although because of their overlapping size distributions these cannot always be readily distinguished. Stromal extracellular vesicles are typically <300 nm in diameter but the placental villous stroma contains much larger...
Wed Sep 11, 2019 20:15
The microarchitecture responsible for compliance of the human aorta is quantified and shown to be highly diverse regionally. The orientation of collagen fibres is non‐symmetric and varies significantly both axially and transmurally, and the density of collagen, elastin and smooth muscle cells is also highly heterogeneous along the aortic length. The quantification of aortic bioarchitecture facilitates the development of next‐generation finite element models that can potentially simulate the influence...
Wed Sep 11, 2019 20:45
Abstract The search for new ligands to treat neuropathic pain remains a challenge. Recently, oxytocin has emerged as an interesting molecule modulating nociception at central and peripheral levels, but no attempt has been made to evaluate the effect of recurrent oxytocin administration in neuropathic pain. Using male Wistar rats with spinal nerve ligation, we evaluated the effects of recurrent spinal (1 nmol; given by lumbar puncture) or peripheral (31 nmol; given by intraplantar...
Thu Sep 12, 2019 03:00
Abstract Acoustic trauma, aging, genetic defects or ototoxic drugs are causes for sensorineural hearing loss involving sensory hair cell death and secondary degeneration of spiral ganglion neurons. Auditory implants are the only available therapy for severe to profound sensorineural hearing loss when hearing aids do not provide a sufficient speech discrimination anymore. Neurotrophic factors represent potential therapeutic candidates to improve the performance of cochlear implants...
Thu Sep 12, 2019 03:00
Publication date: Available online 11 September 2019Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): R.O.H.L. davies, L. Cascarini, D. Coombes, G. Warburton
Thu Sep 12, 2019 16:34
Key points High‐frequency (HF) sniffing represents active odour sampling and an increased animal's motivation We examined how HF sniffing affects the physiological activity of the brain‐body system During HF sniffing, heart rates and the ratio of theta to delta critical local field potential power were comparable to those observed during motion periods Vagus nerve spike rates did not vary depending on HF sniffing. Our results suggest that physiological factors in the central nervous system...
Thu Sep 12, 2019 12:18
Related ArticlesDETERMINATION OF THE TOTAL EFFECTIVE DOSE OF EXTERNAL AND INTERNAL EXPOSURE BY DIFFERENT IONIZING RADIATION SOURCES. Radiat Prot Dosimetry. 2019 Sep 11;: Authors: Kudryashev VA, Kim DS Abstract The purpose of the research is to develop an integrated technique for determining the effective dose (E) of external and internal exposure by different sources of ionizing radiation. The proposing technique for determining the total effective dose...
Thu Sep 12, 2019 16:45
Abstract Upper aerodigestive tract (UADT) malignancies account for significant proportion of all malignancies. The aim of the study is to know the demography and patterns of tobacco consumption and the proportion of non-tobacco consumers in patients with UADT carcinoma. Patient diagnosed with primary UADT carcinoma visiting outpatient department in a tertiary centre from February 2009 to May 2011 were included in the study. 150 patients were documented with UADT carcinoma and analysed....
Thu Sep 12, 2019 03:00
Related ArticlesInhibition of anti-viral responses in intestinal epithelial cells by epigenetic modifying drugs is mediated by a reduction in viral pattern recognition receptor expression and activity. Immunopharmacol Immunotoxicol. 2019 Sep 10;:1-11 Authors: Hennessy C, O'Connell S, Egan LJ, McKernan DP Abstract Background: Pattern recognition receptors form an essential part of the host defenses against pathogens, in particular in the intestinal epithelium....
Thu Sep 12, 2019 16:56
New Findings What is the central question of this study? To investigate if the phase II parameters of pulmonary oxygen uptake (V̇o2) kinetics display linear, first‐order behavior in association with alterations in skeletal muscle oxygenation during step cycling of different intensities or when exercise is initiated from an elevated work rate in youth. What is the main finding and its importance? We demonstrate how both linear and non‐linear features of phase II V̇o2 kinetics may...
Wed Sep 11, 2019 20:44
New Findings What is the central question of this study? Does the magnitude of neuromuscular fatigue depend on the amount of work done (W’) at task failure when cycling above critical power (CP)? What is the main finding and its importance? Creatine supplementation increases W’ and enhances supra‐CP performance, but induces similar magnitudes of neuromuscular fatigue at task failure compared to placebo. Increased W’ does not lead to higher levels of neuromuscular fatigue. This supports...
Thu Sep 12, 2019 16:58
Publication date: October 2019Source: Neoplasia, Volume 21, Issue 10Author(s): Johannes Riegler, Herman Gill, Annie Ogasawara, Maj Hedehus, Vincent Javinal, Jason Oeh, Gregory Z. Ferl, Jan Marik, Simon Williams, Deepak Sampath, Jill Schartner, Richard A.D. CaranoAbstractCancer immunotherapies have demonstrated durable responses in a range of different cancers. However, only a subset of patients responds to these therapies. We set out to test if non-invasive imaging of tumor perfusion and vascular...
Thu Sep 12, 2019 17:00
Publication date: Available online 11 September 2019Source: Annales de Chirurgie Plastique EsthétiqueAuthor(s): E. Arnaud, S.E. Haber, G. Paternoster, S. James, H. Khonsari, MP. Morisseau-Durand, B. Fauroux, V. Viot-Blanc, V. Couloigner, A. Picard, V. Cormier-Daire, M. Robert, C. Legros, M. Zerah, PH. MeyerRésuméLa prise en charge secondaire des craniosténoses simples consiste surtout en des retouches esthétiques, et beaucoup plus rarement en des reprises fonctionnelles (cranioplasties ou insuffisances...
Thu Sep 12, 2019 17:08
Abstract In major‐minor tonal music, the hierarchical relationships and patterns of tension/release are essential for its composition and experience. For most listeners, tension leads to an expectation of resolution. Thus, when musical expectations are broken, they are usually perceived as erroneous and elicit specific neural responses such as the early right anterior negativity (ERAN). In the present study, we explored if different degrees of musical violations are processed differently after long‐term...
Thu Sep 12, 2019 14:08
Publication date: Available online 11 September 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): E. Kolossváry, T. Ferenci, T. Kováts, L. Kovács, Z. Járai, G. Menyhei, K. Farkas
Thu Sep 12, 2019 17:36
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN00859D, PaperThibaut Deviese, Erika Ribechini, Diletta Querci, Thomas HighamBone is one of the main sample types used for building chronologies in archaeology. It is also used in other research areas such as palaeodiet and palaeoenvironmental studies. However, for...The content of this RSS Feed (c) The Royal Society of Chemistry
Thu Sep 12, 2019 02:00
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01136F, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jere Kekkonen, Mikko Finnilä, Jarkko Heikkilä, Vuokko Anttonen, Ilkka NissinenRaman spectroscopy is a powerful analytical tool to be used in many biomedical applications and could be potentially translated into clinical work. The challenge of Raman spectroscopy in biomedical applications...The content of this RSS Feed (c) The...
Thu Sep 12, 2019 02:00
Publication date: Available online 11 September 2019Source: Seminars in OncologyAuthor(s): Ashiq Masood, Rama Krishna Kancha, Janakiraman SubramanianAbstractThe development of first-, second-, and third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) has revolutionized the treatment of patients with nonsmall cell lung cancer (NSCLC) harboring mutations in the EGFR. However, limited data are available regarding the activity of available EGFR TKIs against uncommon...
Thu Sep 12, 2019 17:54
Abstract Background Robotic‐assisted laparoscopic surgery is an operative innovation that has sparked global interest. Over the last decade RALS cases have rapidly increased with over 750,000 robotic procedures completed in 2017. Until recently, Intuitive's da Vinci® surgical system has been the only FDA approved robotic‐assisted surgical device for human procedures. Robotic procedures with the da Vinci require a specific, dedicated training due to the introduction of the technological components...
Wed Sep 11, 2019 21:58
Publication date: Available online 11 September 2019Source: American Journal of Infection ControlAuthor(s): Ahmed Arafa, Ehab S. EshakBackgroundHepatitis B virus (HBV) infection is a significant occupational hazard in health care settings and represents a public health concern. The aim of this study was to investigate the association between medical waste handling and HBV infection by conducting a meta-analysis of available evidence.MethodsPooled odds ratios (ORs) and confidence intervals (CIs) of...
Thu Sep 12, 2019 18:03
Publication date: 15 November 2019Source: NeuroImage, Volume 202Author(s): Chelsea C. Hays, Zvinka Z. Zlatar, M.J. Meloy, Mark W. Bondi, Paul E. Gilbert, Thomas T. Liu, Jonathan L. Helm, Christina E. WierengaAbstractObjectiveThe ε4 allele of the apolipoprotein E (APOE) gene increases risk for cognitive decline in normal and pathologic aging. However, precisely how APOE ε4 exerts its negative impact on cognition is poorly understood. The present study aimed to determine whether APOE genotype (ε4+...
Thu Sep 12, 2019 18:04
Publication date: 15 November 2019Source: NeuroImage, Volume 202Author(s): Yuchuan Qiao, Wei Sun, Yonggang ShiAbstractThe high resolution, multi-shell diffusion MRI (dMRI) data from the Human Connectome Project (HCP) provides a great opportunity to map fine-grained fiber pathways in human brainstem, but the severe susceptibility-induced distortion around the brainstem poses a significant challenge. While the correction tools used in the HCP Pipeline greatly reduce the distortion artifacts in the...
Thu Sep 12, 2019 18:04
Publication date: Available online 11 September 2019Source: Behavioural Brain ResearchAuthor(s): Justin R. Yates, Haley A. Day, Karson E. Evans, Hephzibah O. Igwe, Joy L. Kappesser, Amber L. Miller, Christopher P. Murray, Brett T. Taylor, Alexis L. Ellis, William L. StacyAbstractProcedural modifications can modulate drug effects in delay discounting, such as signaling the delay to reinforcement and altering the order in which delays are presented. Although the schedule of reinforcement can alter...
Thu Sep 12, 2019 18:27
Publication date: Available online 11 September 2019Source: Behavioural Brain ResearchAuthor(s): Lidia Castillo-Mariqueo, Lydia Giménez-LlortAbstractThe study of behavioral and psychological symptoms of dementia (BPSD) has been largely neglected in most experimental research on Alzheimer’s disease (AD) classically focused on cognitive symptoms. The aquatic environment of the Morris water maze (MWM) implies a stressful condition for mice leading to cognitive performances with presence of other behaviors...
Thu Sep 12, 2019 18:27
Publication date: Available online 12 September 2019Source: Behavioural Brain ResearchAuthor(s): Dvijen C. Purohit, Atulya D. Mandyam, Michael J. Terranova, Chitra D. MandyamAbstractAdult female rats show greater running output compared with age-matched male rats, and the midbrain dopaminergic system may account for behavioral differences in running output. However, it is unknown if the lower running output in adult males can be regulated by wheel running experience during adolescence, and whether...
Thu Sep 12, 2019 18:27
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