Πέμπτη 12 Σεπτεμβρίου 2019


Perfusion MRI-Based Fractional Tumor Burden Differentiates between Tumor and Treatment Effect in Recurrent Glioblastomas and Informs Clinical Decision-Making [ADULT BRAIN]
BACKGROUND AND PURPOSE:Fractional tumor burden better correlates with histologic tumor volume fraction in treated glioblastoma than other perfusion metrics such as relative CBV. We defined fractional tumor burden classes with low and high blood volume to distinguish tumor from treatment effect and to determine whether fractional tumor burden can inform treatment-related decision-making.MATERIALS AND METHODS:Forty-seven patients with high-grade gliomas (primarily glioblastoma) with recurrent contrast-enhancing...
Neuroradiology
Thu Sep 12, 2019 18:52
Regional Cerebral Blood Flow in the Posterior Cingulate and Precuneus and the Entorhinal Cortical Atrophy Score Differentiate Mild Cognitive Impairment and Dementia Due to Alzheimer Disease [FUNCTIONAL]
BACKGROUND AND PURPOSE:Alzheimer disease is the most common degenerative dementia affecting humans and mild cognitive impairment is considered the forerunner of this devastating illness with variable progression. Differentiating between them has become all the more essential with the advent of disease-modifying medications. The aim of this study was to test the utility of the entorhinal cortical atrophy score in combination with quantitative CBF in the posterior cingulate and precuneus using arterial...
Neuroradiology
Thu Sep 12, 2019 18:52
White Matter Abnormalities in Multiple Sclerosis Evaluated by Quantitative Synthetic MRI, Diffusion Tensor Imaging, and Neurite Orientation Dispersion and Density Imaging [FUNCTIONAL]
BACKGROUND AND PURPOSE:A number of MR-derived quantitative metrics have been suggested to assess the pathophysiology of MS, but the reports about combined analyses of these metrics are scarce. Our aim was to assess the spatial distribution of parameters for white matter myelin and axon integrity in patients with relapsing-remitting MS by multiparametric MR imaging.MATERIALS AND METHODS:Twenty-four patients with relapsing-remitting MS and 24 age- and sex-matched controls were prospectively scanned...
Neuroradiology
Thu Sep 12, 2019 18:52
Reply: [LETTERS]
Neuroradiology
Thu Sep 12, 2019 19:12
Challenges in Differentiating Pediatric Autoimmune CNS Diseases with Similar Clinical and Imaging Phenotypes [LETTERS]
Neuroradiology
Thu Sep 12, 2019 19:25
Diagnostic Value of Bone SPECT/CT in Patients with Suspected Osteomyelitis
Related ArticlesDiagnostic Value of Bone SPECT/CT in Patients with Suspected Osteomyelitis Mol Imaging Radionucl Ther. 2019 09 06;28(3):89-95 Authors: Arıcan P, Okudan B, Şefizade R, Naldöken S Abstract Objectives: The aim of our retrospective study was to evaluate the contribution of single photon emission computed tomography/computed tomography (SPECT/CT) to three phase bone scintigraphy/SPECT for the assessment of osteomyelitis (OM) and patient’s...
Mol Imaging Radionucl Ther
04:45
Effects of the Use of Automatic Tube Current Modulation on Patient Dose and Image Quality in Computed Tomography
Related ArticlesEffects of the Use of Automatic Tube Current Modulation on Patient Dose and Image Quality in Computed Tomography Mol Imaging Radionucl Ther. 2019 09 06;28(3):96-103 Authors: Yurt A, Özsoykal İ, Obuz F Abstract Objectives: The frequency of abdominal computed tomography examinations is increasing, leading to a significant level of patient dose. This study aims to quantify and evaluate the effects of automatic tube current modulation (ATCM)...
Mol Imaging Radionucl Ther
04:45
Correlation of SUVmax and Apparent Diffusion Coefficient Values Detected by Ga-68 PSMA PET/MRI in Primary Prostate Lesions and Their Significance in Lymph Node Metastasis: Preliminary Results of an On-going Study
Related ArticlesCorrelation of SUVmax and Apparent Diffusion Coefficient Values Detected by Ga-68 PSMA PET/MRI in Primary Prostate Lesions and Their Significance in Lymph Node Metastasis: Preliminary Results of an On-going Study Mol Imaging Radionucl Ther. 2019 Sep 06;28(3):104-111 Authors: Uslu-Beşli L, Bakır B, Asa S, Güner E, Demirdağ Ç, Şahin OE, Karayel E, Sağer MS, Sayman HB, Sönmezoğlu K Abstract Objectives: Gallium-68 (Ga-68) prostate specific...
Mol Imaging Radionucl Ther
04:45
Solitary Pulmonary Nodule: Morphological Effects on Metabolic Activity Assessment
Related ArticlesSolitary Pulmonary Nodule: Morphological Effects on Metabolic Activity Assessment Mol Imaging Radionucl Ther. 2019 Sep 06;28(3):112-119 Authors: Erdoğan M, Evrimler Ş, Aydın H, Karaibrahimoğlu A, Şengül SS Abstract Objectives: We aimed to evaluate the effects of morphological characteristics of the solitary pulmonary nodules (SPN) on metabolic activity assessment. To the best of our knowledge, this is the first study to compare the volumetric...
Mol Imaging Radionucl Ther
04:45
Minimal Invasive Radioguided Ectopic Parathyroidectomy in Upper Mediastinum
Related ArticlesMinimal Invasive Radioguided Ectopic Parathyroidectomy in Upper Mediastinum Mol Imaging Radionucl Ther. 2019 Sep 06;28(3):120-122 Authors: Koç ZP, Karlıdağ T, Özcan Kara P, Akyiğit A, Dağlı F Abstract In this study we wanted to present a case with the history of multiple previous neck explorations and persisting upper mediastinal ectopic parathyroid adenoma who underwent a successful operation with radioguided minimal invasive approach.PMID:...
Mol Imaging Radionucl Ther
04:45
Incidental “Urinoma” in 18F-FDG PET/CT Scan
Related ArticlesIncidental “Urinoma” in 18F-FDG PET/CT Scan Mol Imaging Radionucl Ther. 2019 Sep 06;28(3):123-125 Authors: Gültekin A, Yaylalı O, Şengöz T, Yüksel D Abstract 18F-FDG PET/CT scanning was performed for the primary staging of a 47-year-old man with urothelial carcinoma. The patient underwent biopsy by ureteroscopy 15 days ago and the PET images revealed 18F-FDG accumulation in the right retroperitenal region, compatible with an “urinoma”.PMID:...
Mol Imaging Radionucl Ther
04:45
PET/CT Findings of a Patient with Cardiac Metastasis of Subungual Malign Melanoma
Related ArticlesPET/CT Findings of a Patient with Cardiac Metastasis of Subungual Malign Melanoma Mol Imaging Radionucl Ther. 2019 Sep 06;28(3):126-128 Authors: Ekmekçioğlu Ö, Arıcan P, Meşe Ş, Kaplan N, Kafi M, Şimşek D, Ertürk MŞ Abstract A 58-year old patient with a history of subungual malign melanoma was referred to our department for a 18F-FDG positron emission tomography (PET)/computed tomography (CT) whole body scan. An unexpected 18F-FDG uptake...
Mol Imaging Radionucl Ther
04:45
Ileal Neuroendocrin Tumor Metastasis to Breast Diagnosed with Ga-68 DOTATATE PET/CT
Related ArticlesIleal Neuroendocrin Tumor Metastasis to Breast Diagnosed with Ga-68 DOTATATE PET/CT Mol Imaging Radionucl Ther. 2019 Sep 06;28(3):129-131 Authors: Sağlampınar Karyağar S, Güven O, Karyağar S Abstract Breast metastasis of the well differentiated neuroendocrin tumor (WDNET) of the ileum is very rare. A case of a 62-year-old woman with ileal WDNET, who underwent restaging with Ga-68 DOTATATE PET/CT due to progression of metastatic lesions...
Mol Imaging Radionucl Ther
04:45
Head and neck squamous cell cancers in the United States are rare and the risk now is higher among white individuals compared with black individuals.
Related ArticlesHead and neck squamous cell cancers in the United States are rare and the risk now is higher among white individuals compared with black individuals. Cancer. 2018 05 15;124(10):2125-2133 Authors: Fakhry C, Krapcho M, Eisele DW, D'Souza G Abstract BACKGROUND: The increasing incidence of oropharyngeal squamous cell cancer (OPSCC) is well established. However, up-to-date incidence estimates and trends for head and neck squamous cell cancers...
Subgroups in Laryngeal Carcinoma
04:46
Impact of transition to a subterranean lifestyle on morphological disparity and integration in talpid moles (Mammalia, Talpidae)
Understanding the mechanisms promoting or constraining morphological diversification within clades is a central topic in evolutionary biology. Ecological transitions are of particular interest because of their...
BMC Evolutionary Biology - Latest Articles
Thu Sep 12, 2019 03:00
Being “Out” in the Field: Who Is Responsible for Health and Safety?
International Journal of Primatology
03:00
Protective effects of Lactobacillus plantarum against chronic alcohol-induced liver injury in the murine model
Abstract Long-term alcohol consumption causes liver injuries such as alcoholic hepatitis, fatty liver, and endotoxemia. Some probiotics were demonstrated to exert beneficial effects in the gastrointestinal tract. The present study was aimed to evaluate the protective effects of Lactobacillus plantarum CMU995 against alcohol-induced liver injury. The mice were orally administered L. plantarum CMU995 for 1 week, followed by the administration of alcohol and different tested substances...
Latest Results for Applied Microbiology and Biotechnology
Thu Sep 12, 2019 03:00
Production of sesterterpene ophiobolin by a bifunctional terpene synthase in Escherichia coli
Abstract Ophiobolins (ophs) are characteristic 5-8-5 tricyclic sesterterpenes with potential pharmaceutical activities. Ophiobolin synthase is a bifunctional terpene synthase (BTS) that catalyzes both chain elongation and cyclization. In Aspergillus ustus 094102, ophiobolin accumulation was involved with not only ophiobolin synthase C25 (Au8003) but also other four gene clusters containing C15 (Au6298), C20 (Au13192 and Au11565), and C30 (Au3446) terpene synthases. In this report,...
Latest Results for Applied Microbiology and Biotechnology
Thu Sep 12, 2019 03:00
New sustainable alternatives to reduce the production costs for surfactin 50 years after the discovery
Abstract In 1968, Arima et al. discovered the heptapeptide, known as surfactin, which belongs to a family of lipopeptides. Known for its ability to reduce surface tension, it also has biological activities such as antimicrobial and antiviral. Its non-ribosomal synthesis mechanism was later discovered (1991). Lipopeptides represent an important class of surfactants, which can be applied in many industrial sectors such as food, pharmaceutical, agrochemicals, detergents, and cleaning...
Latest Results for Applied Microbiology and Biotechnology
03:00
Seasonal bacterial community dynamics in a crude oil refinery wastewater treatment plant
Abstract The biological treatment of oil refinery effluents in wastewater treatment plants (WWTPs) relies on specialized bacteria contributing to remove organic load, nitrogen, sulfur, and phosphorus compounds. Knowledge about bacterial dynamics in WWTPs and how they affect the performance of the wastewater treatment is limited, particularly in tropical countries. The bacterial communities from three compartments of an oil refinery WWTP in Uran, India, were assessed using 16S-metabarcoding,...
Latest Results for Applied Microbiology and Biotechnology
03:00
Use of Individual Anatomical Variations to Customise Window Location in Montgomery Implant Thyroplasty: A Case Series Study
Abstract Medialization thyroplasty with Montgomery implant uses sex‐based criteria, which can occasionally lead to suboptimal positioning of the prosthesis. We described a surgical procedure and a set of measurement devices which can be used to customise the placement of cartilage‐windows. This case series study describes the changes in the cartilage‐window location compared to standard the window placement recommended by Montgomery. All the patients except one required window adjustment; in...
Clinical Otolaryngology
Thu Sep 12, 2019 13:38
Cochlear Implantation in the Presence of Superficial Siderosis
Abstract Objective To study the outcome of cochlear implantation in patients with superficial siderosis of the central nervous system. Study Design: Retrospective study Methods A chart review was performed on all patients with the diagnosis of superficial siderosis and subsequently underwent cochlear implantation between the years 2009 and 2016. Data extracted included patient demographics, pre‐operative and post‐operative audiological performance. Main Outcome Measures Post‐operative...
Clinical Otolaryngology
Thu Sep 12, 2019 13:44
Pharmacokinetics of L-Triiodothyronine in Patients Undergoing Thyroid Hormone Therapy Withdrawal
Thyroid, Ahead of Print.
liebertpub1
Thu Sep 12, 2019 10:00
Effect of Ceftaroline, Vancomycin, Gentamicin, Macrolides, and Ciprofloxacin against Methicillin-Resistant Staphylococcus aureus Isolates: An In Vitro Study
Surgical Infections, Ahead of Print.
Surgical Infections
Thu Sep 12, 2019 10:00
Caught in the Web — U.S. Immigration and Compound Disadvantage
Three years ago, Mr. V. made his way on foot from Honduras to the United States, leaving his family behind. When he left home, he’d had a globus sensation and occasional anxiety for 2 or 3 years, and since his arrival in the United States, the globus sensation had been coming on more frequently,…
The New England Journal of Medicine: Search Results in Health Policy and Reform
Thu Sep 12, 2019 03:00
Changing Principals, Keeping Principles
After a global search, the Journal found a new editor-in-chief within 100 yards of the editorial offices. I was already an Associate Editor at the Journal, and I share a similar Boston-based academic background with my predecessor. These factors do not suggest that much is going to change. But…
The New England Journal of Medicine: Search Results in Health Policy and Reform
Thu Sep 12, 2019 03:00
Survival nomogram for patients with initially diagnosed metastatic non-small-cell lung cancer: a SEER-based study
Future Oncology, Ahead of Print.
Future Oncology
Thu Sep 12, 2019 04:47
OScc: an online survival analysis web server to evaluate the prognostic value of biomarkers in cervical cancer
Future Oncology, Ahead of Print.
Future Oncology
Thu Sep 12, 2019 06:21
The NEOLETEXE trial: a neoadjuvant cross-over study exploring the lack of cross resistance between aromatase inhibitors
Future Oncology, Ahead of Print.
Future Oncology
Thu Sep 12, 2019 07:48
Sarcoma patients’ quality of life from diagnosis to yearly follow-up: experience from an Italian tertiary care center
Future Oncology, Ahead of Print.
Future Oncology
Thu Sep 12, 2019 13:50
Comparison of survival outcomes in medullary carcinoma and invasive ductal carcinoma of the breast
Future Oncology, Ahead of Print.
Future Oncology
Thu Sep 12, 2019 14:05
A Phase III open-label trial to evaluate efficacy and safety of CPI-613 plus modified FOLFIRINOX (mFFX) versus FOLFIRINOX (FFX) in patients with metastatic adenocarcinoma of the pancreas
Future Oncology, Ahead of Print.
Future Oncology
Thu Sep 12, 2019 14:31
Devimistat in combination with high dose cytarabine and mitoxantrone compared with high dose cytarabine and mitoxantrone in older patients with relapsed/refractory acute myeloid leukemia: ARMADA 2000 Phase III study
Future Oncology, Ahead of Print.
Future Oncology
Thu Sep 12, 2019 14:53
Magnitude of enteropathogens and associated factors among apparently healthy food handlers at Wolkite University Student’s Cafeteria, Southern Ethiopia
The study aimed to assess enteropathogens carriage rate and risk factors among apparently healthy food handlers at Wolkite University cafeteria, Southern Ethiopia.
BMC Research Notes
Wed Sep 11, 2019 03:00
A comparison of ocular trauma scores in a pediatric population
Pediatric ocular trauma represents a major concern for ophthalmologists. Delays in presentation, incomplete exams, inaccurate visual acuity (VA) results, and amblyopia can limit accurately predicting final vis...
BMC Research Notes
Wed Sep 11, 2019 03:00
Feasibility of flow cytometric analysis of restricted light chain in endoscopic biopsy specimens from patients with gastrointestinal tract B cell lymphoma: a pilot study
Gastrointestinal tract lymphomas are currently detected more frequently due to advances in endoscopic technology. The aim of this study was to assess the feasibility of flow cytometric analysis of restricted l...
BMC Research Notes
Wed Sep 11, 2019 03:00
Mitochondrial DNA variation of the ruffed grouse (Bonasa umbellus)
The ruffed grouse, Bonasa umbellus, is broadly distributed across North America and displays considerable taxonomic diversity. Except for a genetic study of some western populations of ruffed grouse, nothing is k...
BMC Research Notes
Wed Sep 11, 2019 03:00

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