Related ArticlesLeukemia Stem Cells in Chronic Myeloid Leukemia. Adv Exp Med Biol. 2019;1143:191-215 Authors: Shan Y, DeSouza N, Qiu Q, Li S Abstract Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder characterized by a chromosome translocation that generates the BCR-ABL oncogene encoding a constitutively activated tyrosine kinase. Although BCR-ABL tyrosine kinase inhibitors (TKIs) are highly effective in treating CML at chronic...
Tue Sep 10, 2019 13:05
Related ArticlesCellular and Molecular State of Myeloid Leukemia Stem Cells. Adv Exp Med Biol. 2019;1143:41-57 Authors: Xie X, Feng M, Wang Q, Wang J, Yin R, Li Y, Zhang H Abstract Leukemia stem cells (LSCs) are leukemia-initiating population with the capacity to self-renew, differentiate, and stay quiescent. Human hematopoietic malignancies such as chronic myeloid leukemia (CML) and acute myeloid leukemia (AML) are derived from this cell population....
Tue Sep 10, 2019 13:05
Related ArticlesBleeding Disorders Associated with Cancer. Cancer Treat Res. 2019;179:191-203 Authors: Mantha S Abstract Cancer can be associated with several distinct coagulation defects which can lead to bleeding complications. The primary hyperfibrinolytic syndrome associated with acute promyelocytic leukemia has been well recognized and is one of the most severe bleeding disorders. Acquired hemophilia, while rare and not only seen in the oncology...
Tue Sep 10, 2019 13:05
Related ArticlesEtiology and Management of Upper-Extremity Catheter-Related Thrombosis in Cancer Patients. Cancer Treat Res. 2019;179:117-137 Authors: Rajasekhar A, Streiff MB Abstract Central venous access devices are a critical instrument in the treatment and supportive care delivery for oncology patients. Catheter-related thrombosis (CRT) is a common complication of central venous access devices in oncology patients. Risk factors for CRT include...
Tue Sep 10, 2019 13:05
Related Articles[Malignant collision tumor of the skin : Melanoma, squamous cell carcinoma and basal cell carcinoma]. Pathologe. 2019 Sep;40(5):534-538 Authors: Sterz H, Kendler M, Simon JC, Ziemer M Abstract We present the case of a woman in her eighties with a collision tumor composed of a malignant melanoma, a squamous cell carcinoma and a basal cell carcinoma. The simultaneous growth of histogenetically different, spatially not separate, malignant...
Tue Sep 10, 2019 13:05
Related ArticlesInterventions for the treatment of Paget's disease of the vulva. Cochrane Database Syst Rev. 2019 06 05;6:CD009245 Authors: Edey KA, Allan E, Murdoch JB, Cooper S, Bryant A Abstract BACKGROUND: This is an updated version of the original Cochrane Review published in Issue 10, 2013.Extramammary Paget's disease is a rare form of superficial skin cancer. The most common site of involvement is the vulva. It is seen mainly in postmenopausal...
Tue Sep 10, 2019 13:05
Related Articles[Syndromes with scales and keratosis]. Hautarzt. 2019 Jul;70(7):497-505 Authors: Fischer J Abstract Approximately 9000 different phenotypes are known in medicine. The definition phenotype includes both manifest diseases as well as features without any disease value and the pure genetic disposition to develop a disease (e.g. tumors or complex diseases); however, most phenotypes are rare monogenic hereditary diseases. Approximately 6400...
Tue Sep 10, 2019 13:05
Related ArticlesFunctional and oncological outcomes after retropharyngeal node dissection for papillary thyroid carcinoma. Eur Arch Otorhinolaryngol. 2019 Jun;276(6):1809-1814 Authors: Otsuki N, Morita N, Furukawa T, Teshima M, Shinomiya H, Shinomiya H, Nibu KI Abstract BACKGROUND: Papillary thyroid carcinoma frequently metastasizes to central and lateral neck lymph nodes, but metastasis to retropharyngeal lymph nodes (RPLN) is rare. PATIENTS...
Tue Sep 10, 2019 13:05
Related Articles[Dermatological follow-up in retinoblastoma patients : A case report]. Hautarzt. 2019 Apr;70(4):290-292 Authors: Seitz AT, Beyer S, Simon JC, Grunewald S Abstract We report a well-differentiated liposarcoma and multiple lipomas in a patient with bilateral retinoblastoma at the age of two. Well-differentiated liposarcoma of the skin are rare and have a good prognosis. Lipomas are in those cases a good indicator for a higher risk of secondary...
Tue Sep 10, 2019 13:05
Related ArticlesManagement of Localized Breast Angiosarcoma by North American Radiation and Medical Oncologists. Clin Breast Cancer. 2018 12;18(6):498-503 Authors: Hatfield J, McClelland S, Luo J, Degnin C, Chen Y, Maggiore RJ, Mitin T Abstract INTRODUCTION: Primary breast angiosarcoma is a rare malignancy with no clinical trials to guide management. The current use of surgery, chemotherapy, and radiotherapy among North American oncologists is unknown....
Tue Sep 10, 2019 13:05
Related ArticlesGenetic Analysis of Copy Number Variation in Large Chorangiomas. Pediatr Dev Pathol. 2019 May-Jun;22(3):236-242 Authors: Sirotkina M, Douroudis K, Westgren M, Papadogiannakis N Abstract INTRODUCTION: Chorangioma (CA) is the most common nontrophoblastic, vascular tumor-like lesion of the placenta with a reported incidence of 0.5% to 1% in all examined placentas. The underlying molecular mechanisms of CAs are still poorly elucidated, and...
Tue Sep 10, 2019 13:05
Related Articles[Successful pembrolizumab therapy in metastasized adenosquamous carcinoma of the colon]. Pathologe. 2019 Sep;40(5):540-545 Authors: Evert K, Stiegler C, Schäfer C, Palme K, Horndasch E, Reitinger S, Rau BM, Dietmaier W, Evert M Abstract Adenosquamous carcinoma (ASqC) is an exceedingly rare subtype of colorectal cancer without any known special guidelines for treatment. The biological behaviour and molecular background are widely unknown,...
Tue Sep 10, 2019 13:05
Related ArticlesSquamous cell carcinoma of the rectum cured after chemoradiation. Tunis Med. 2018 Jan;96(1):87-88 Authors: Mrabet S, Hallara O, Loghmari H, Ben Mansour W, Bouhlel W, Safer L Abstract The primary squamous cell carcinoma of the rectum is a rare tumor that presents epidemiological, etiopathogenic and evolutionary characteristics different from those of adenocarcinoma . We report the case of a primary squamous cell carcinoma well differentiated ...
Tue Sep 10, 2019 13:05
Related ArticlesMyxoid chondrosarcoma extraskeletal in pelvis location : a case report. Tunis Med. 2018 Jan;96(1):84-86 Authors: Chahdi H, Chafry B, Allaoui M Abstract BACKGROUND: The extraskeletal myxoid chondrosarcoma (CME) is a rare tumor of the soft tissue, with clinically distinguishable clinical, histological, immunohistochemical, cytogenetic and evolutionary characteristics with an unfavorable long-term prognosis. CASE: We reported the...
Tue Sep 10, 2019 13:05
Related ArticlesDiagnostic features of elastofibroma dorsi: about 4 cases. Tunis Med. 2018 Jan;96(1):64-67 Authors: Barsaoui M, Riahi H, Chelly Bouaziz M, Ladeb MF Abstract Elastofibromas are rare benign soft tissue tumors that are commonly located at the inferior pole of the scapula, typically in the right side, deep to the serratus anterior muscle. They occur mainly in elderly women and are usually asymptomatic. We present four cases of elastofibroma...
Tue Sep 10, 2019 13:05
Related ArticlesSuccinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor With SDHC Germline Mutation and Bilateral Renal and Neck Cysts. Pediatr Dev Pathol. 2019 May-Jun;22(3):265-268 Authors: Stanley K, Friehling E, Davis A, Ranganathan S Abstract Gastrointestinal stromal tumors (GISTs) are rare in children. Succinate dehydrogenase (SDH)-deficient GISTs are wild type and lack KIT proto-oncogene receptor tyrosine kinase and platelet-derived...
Tue Sep 10, 2019 13:05
Related ArticlesSecretory breast carcinoma in an 8-year-old girl: A case report and literature review. Breast J. 2018 11;24(6):1055-1061 Authors: Garlick JW, Olson KA, Downs-Kelly E, Bucher BT, Matsen CB Abstract Secretory breast carcinoma (SBC) is a rare form of breast cancer found in both children and adults, and is the most common breast cancer in the pediatric population. Although SBC usually carries a favorable prognosis, there have been reported...
Tue Sep 10, 2019 13:05
Related ArticlesA rare case of pleomorphic adenoma of the breast: Ultrasonography and pathology findings. Breast J. 2018 11;24(6):1069-1070 Authors: Arslan A, Güldoğan N, Kapucuoğlu N, Esen G, Kara H, Uras C PMID: 30240069 [PubMed - indexed for MEDLINE]
Tue Sep 10, 2019 13:05
Related ArticlesParaneoplastic neurologic syndrome as a presentation of underlying breast malignancy. Breast J. 2018 11;24(6):1038-1042 Authors: Laguna B, Hayward JH, Lee AY, Joe BN, Ray KM Abstract While breast cancer most commonly presents as a screen-detected mammographic finding or a breast symptom, in very rare instances it may first present as a paraneoplastic neurologic syndrome (PNS; Surg Case Rep, 2015;1:59; Ann Neurol 2004;56:715). Fewer than...
Tue Sep 10, 2019 13:05
Related ArticlesCutaneous Metastasis of Sigmoid Adenocarcinoma to Face and Scalp at Initial Diagnosis: Case Report. Gulf J Oncolog. 2018 May;1(27):70-72 Authors: Alotaibi M, Nemec J Abstract Cutaneous metastases from colorectal cancer are very rare. They appear in less than 0.5% of colorectal metastatic cases at time of initial diagnosis. They indicate disseminated disease and poor prognosis. We describe a case of 54 years old patient who presented with...
Tue Sep 10, 2019 13:05
Related ArticlesMalignant Phyllodes tumor in a young female: A Case Report. Gulf J Oncolog. 2018 May;1(27):64-69 Authors: Anand P, Sarin N, Butti AK, Singh S Abstract Phyllodes tumor is a rare fibroepithelial neoplasm of the breast and constitutes 0.3-0.5% of all breast tumors. They are usually benign and only few of them undergo malignant transformation. Benign or borderline phyllodes tumor typically never recur however, malignant phyllodes tumors do...
Tue Sep 10, 2019 13:05
Post-infectious transverse myelitis in an older adult: A rare complication of Klebsiella bacteremia.
Related ArticlesPost-infectious transverse myelitis in an older adult: A rare complication of Klebsiella bacteremia. Geriatr Gerontol Int. 2018 07;18(7):1135-1136 Authors: Lim JS, Putta SN, Pada S, Lee JE PMID: 30133965 [PubMed - indexed for MEDLINE]
Tue Sep 10, 2019 13:05
Related ArticlesInfantile Myofibromatosis With Intracranial Extradural Involvement and PDGFRB Mutation: A Case Report and Review of the Literature. Pediatr Dev Pathol. 2019 May-Jun;22(3):258-264 Authors: Al Qawahmed R, Sawyer SL, Vassilyadi M, Qin W, Boycott KM, Michaud J Abstract Infantile myofibroma is a rare benign mesenchymal tumor that presents as solitary or multiple lesions (myofibromatosis) in the skin, soft tissue, bone, or internal organs....
Tue Sep 10, 2019 13:05
Related ArticlesThe Way Forward for Mechanism-Based Therapeutics in Genetically Defined Neurodevelopmental Disorders. Clin Pharmacol Ther. 2018 10;104(4):603-606 Authors: Modi ME, Sahin M Abstract Rare genetically defined neurodevelopmental disorders with increased risk of autism have recently become an entry point for autism-related drug discovery. Through exploration of downstream effects of the pathological mutations, specific mechanistic pathways...
Tue Sep 10, 2019 13:05
Related Articles[A rare renal tumour : Ectopic thyroid tissue in the kidney]. Urologe A. 2018 Aug;57(8):944-946 Authors: Mata Mera C, Kreutzer N, Lorenzen J, Truß M Abstract During a nephrectomy of a nonfunctioning, tumour-bearing kidney we found ectopic thyroid tissue in the kidney. This location of ectopic thyroid tissue has not been described before. In general, ectopic thyroid tissue is uncommon and rather found in the cervical region or upper mediastinum....
Tue Sep 10, 2019 13:05
Related ArticlesSézary Syndrome Presenting With Renal Involvement. Am J Kidney Dis. 2018 12;72(6):890-894 Authors: Wickenden K, Graham-Brown MPM, Veitch D, Dormer J, Bamford M, Graham-Brown RAC, Warwick G, Wagner S, Burton JO Abstract Sézary syndrome is a rare aggressive leukemic variant of primary cutaneous T-cell lymphoma, typically presenting with erythroderma, lymphadenopathy, and an atypical clonal T-cell population. Though it often involves the...
Tue Sep 10, 2019 13:05
Related ArticlesAn interdisciplinary consensus on the management of bone metastases from renal cell carcinoma. Nat Rev Urol. 2018 08;15(8):511-521 Authors: Grünwald V, Eberhardt B, Bex A, Flörcken A, Gauler T, Derlin T, Panzica M, Dürr HR, Grötz KA, Giles RH, von Falck C, Graser A, Muacevic A, Staehler M Abstract Bone is a major site of haematogenous tumour cell spread in renal cell carcinoma (RCC), and most patients with RCC will develop painful and...
Tue Sep 10, 2019 13:05
Related ArticlesSpontaneous azygos vein thrombosis: a rare entity. Br J Hosp Med (Lond). 2018 May 02;79(5):294 Authors: Abdulla O, Ahmad S PMID: 29727230 [PubMed - indexed for MEDLINE]
Tue Sep 10, 2019 13:05
Related ArticlesThe Predictive Value of Staging Systems and Inflammation Scores for Patients with Combined Hepatocellular Cholangiocarcinoma After Surgical Resection: a Retrospective Study. J Gastrointest Surg. 2018 07;22(7):1239-1250 Authors: He C, Mao Y, Wang J, Song Y, Huang X, Lin X, Li S Abstract BACKGROUND: Combined hepatocellular cholangiocarcinoma (cHCC-CC) is a rare form of primary liver tumor. A specific staging system for predicting survival...
Tue Sep 10, 2019 13:05
Related ArticlesVaginal metastasis of renal clear-cell cancer. Gulf J Oncolog. 2018 Jan;1(26):67-71 Authors: Rehailia-Blanchard A, Morel A, Rancoul C, He MY, Magné N, Falkowski S Abstract BACKGROUND: Vaginal metastases originating from renal cancer remain a rare event, with less than 100 cases reported in the literature. The spreading mechanism is still under scrutiny. The tumoral bleeding often is a symptom revealing vaginal metastases. CASE:...
Tue Sep 10, 2019 13:05
Related ArticlesTumor Recurrence at Donor Site of Pectoralis Major Myocutaneous Flap with Tumor-free Primary Oral Carcinoma. Gulf J Oncolog. 2018 Jan;1(26):64-66 Authors: Kain R, Dash S Abstract Pectoralis major myocutaneous flap is an important option for post onco reconstruction in head and neck region. Among the several complications mentioned in the literature, tumor recurrence at the donor site of flap is late and rare complication. Tumor implantation...
Tue Sep 10, 2019 13:05
Related ArticlesLymphoid proliferation in Eyelid: A Primary Follicular Lymphoma Case. Gulf J Oncolog. 2018 Jan;1(26):58-60 Authors: Cruzado-Sánchez D, Tellez WA, Serpa-Frias S, Maquera G Abstract Ocular adnexal lymphoma (OAL) constitutes 8% of all extranodal lymphomas, being rare in the eyelids (5-20%). The objective was to report a case of eyelid follicular lymphoma in a young adult woman. A 35-year-old female with swelling in left lower eyelid with...
Tue Sep 10, 2019 13:05
Related ArticlesExtramedullary Blast Crisis in a Patient with T315I BCR-ABL Mutated Chronic Myeloid Leukemia. Clin Lab. 2018 Jan 01;64(1):193-196 Authors: Zhang J, Zhang X, Lu Y, Jiao J, Chen Y, Lin D Abstract BACKGROUND: Extramedullary blast crisis (EBC) of T315I BCR-ABL mutated chronic myelogenous leukemia (CML) is extremely rare. METHODS: We report an unusual case characterized by fever, right shoulder swelling, pleural effusion, and multiple...
Tue Sep 10, 2019 13:05
Related ArticlesNew Insights into the Molecular Characteristics of Pulmonary Carcinoids and Large Cell Neuroendocrine Carcinomas, and the Impact on Their Clinical Management. J Thorac Oncol. 2018 06;13(6):752-766 Authors: Derks JL, Leblay N, Lantuejoul S, Dingemans AC, Speel EM, Fernandez-Cuesta L Abstract Carcinoids and large cell neuroendocrine carcinomas (LCNECs) are rare neuroendocrine lung tumors. Here we provide an overview of the most updated...
Tue Sep 10, 2019 13:05
Related ArticlesChromosomal aberrations in chordoid meningioma - An analysis. Neurol India. 2018 Jan-Feb;66(1):156-160 Authors: Sugur H, Shastry AH, Sadashiva N, Srinivas D, Santosh V, Somanna S Abstract INTRODUCTION: Chordoid meningiomas (CMs) are a rare subgroup of tumors, accounting for approximately 0.5% of all meningiomas. These tumors correspond to World Health Organization (WHO) Grade II lesions and behave aggressively, with an increased likelihood...
Tue Sep 10, 2019 13:05
Related ArticlesFacial nerve schwannomas: A case series with an analysis of imaging findings. Neurol India. 2018 Jan-Feb;66(1):139-143 Authors: Sah SK, Guo YY, Mahaseth N, Chen Y, Du S, Li Y Abstract Facial nerve schwannomas (FNSs) are rare benign tumors arising from the Schwann cells of the sheath of the facial nerve. These tumors may arise anywhere along the course of the facial nerve. Owing to their rarity and nonspecific clinical and radiological...
Tue Sep 10, 2019 13:05
Related ArticlesA Large Intussuscepting Gastric Lipoma. J Gastrointest Surg. 2018 07;22(7):1299-1300 Authors: Reza JA, Fruchter S, Varadarajulu S, Arnoletti JP Abstract Lipomas of the lower foregut are exceptionally rare. Presenting symptoms often include bleeding, weight loss, and obstructive symptoms. Surgical resection remains the standard treatment. We report a case of a large intussuscepting gastric lipoma.PMID: 29255956 [PubMed - indexed for MEDLINE]
Tue Sep 10, 2019 13:05
Related ArticlesPD-1 Inhibitor-associated Myopathies: Emerging Immune-mediated Myopathies. J Immunother. 2018 05;41(4):208-211 Authors: Liewluck T, Kao JC, Mauermann ML Abstract Programmed death-1 (PD-1) inhibitors are increasingly used in cancer immunotherapy. Various immune-related adverse events are reported, including infrequent individual case reports of myositis or rhabdomyolysis. The frequency and diagnostic spectrum of immune-related adverse...
Tue Sep 10, 2019 13:05
Related ArticlesThe surgical treatment of tumors of the fourth ventricle: a single-institution experience. J Neurosurg. 2018 02;128(2):339-351 Authors: Ferguson SD, Levine NB, Suki D, Tsung AJ, Lang FF, Sawaya R, Weinberg JS, McCutcheon IE Abstract OBJECTIVE Fourth ventricle tumors are rare, and surgical series are typically small, comprising a single pathology, or focused exclusively on pediatric populations. This study investigated surgical outcome...
Tue Sep 10, 2019 13:05
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