IJMS, Vol. 21, Pages 2455: Shape Anisotropic Iron Oxide-Based Magnetic Nanoparticles: Synthesis and Biomedical Applications International Journal of Molecular Sciences doi: 10.3390/ijms21072455 Authors: Raquel G. D. Andrade Sérgio R. S. Veloso Elisabete M. S. Castanheira Research on iron oxide-based magnetic nanoparticles and their clinical use has been, so far, mainly focused on the spherical shape. However, efforts have been made to develop synthetic routes that produce different...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2454: Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967 International Journal of Molecular Sciences doi: 10.3390/ijms21072454 Authors: Mason Cummins Many epilepsy patients are refractory to conventional antiepileptic drugs. Resurgent and persistent currents can be enhanced by epilepsy mutations in the Nav1.2 channel, but conventional antiepileptic drugs inhibit normal transient currents through these channels,...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2452: A Coil-to-Helix Transition Serves as a Binding Motif for hSNF5 and BAF155 Interaction International Journal of Molecular Sciences doi: 10.3390/ijms21072452 Authors: Jeongmin Han Iktae Kim Jae-Hyun Park Ji-Hye Yun Keehyoung Joo Taehee Kim Gye-Young Park Kyoung-Seok Ryu Yoon-Joo Ko Kenji Mizutani Sam-Young Park Rho Hyun Seong Jooyoung Lee Jeong-Yong Suh Weontae Lee Human SNF5 and BAF155 constitute the core subunit of...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2450: Tumor Milieu Controlled by RB Tumor Suppressor International Journal of Molecular Sciences doi: 10.3390/ijms21072450 Authors: Kitajima Li Takahashi The RB gene is one of the most frequently mutated genes in human cancers. Canonically, RB exerts its tumor suppressive activity through the regulation of the G1/S transition during cell cycle progression by modulating the activity of E2F transcription factors. However, aberration of the RB gene is most...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2449: Role of Chitin Deacetylase 1 in the Molting and Metamorphosis of the Cigarette Beetle Lasioderma serricorne International Journal of Molecular Sciences doi: 10.3390/ijms21072449 Authors: Yang Xu Yan Li Jin Chitin deacetylases (CDAs) are chitin-modifying enzymes known to play vital roles in insect metamorphosis and development. In this study, we identified and characterized a chitin deacetylase 1 gene (LsCDA1) from the cigarette beetle Lasioderma...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2448: Cloning, Molecular Characterization and Expression Patterns of DMRTC2 Implicated in Germ Cell Development of Male Tibetan Sheep International Journal of Molecular Sciences doi: 10.3390/ijms21072448 Authors: Li Zhang Wang Yin Chen Kang Zhao Ma The double sex and mab-3-related transcription factors like family C2 (DMRTC2) gene is indispensable for mammalian testicular function and spermatogenesis. Despite its importance, what expression...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2445: Comparative Transcriptome Analysis Reveals the Potential Mechanism of Abortion in Tobacco sua-Cytoplasmic Male Sterility International Journal of Molecular Sciences doi: 10.3390/ijms21072445 Authors: Liu Liu Sun Yang Li sua-CMS (cytoplasmic male sterility) is the only male sterile system in tobacco breeding, but the mechanism of abortion is unclear. Cytological characteristics show that abortion in the sua-CMS line msZY occurs before the differentiation...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2447: Synthesis of Dinaphtho[2,3-d:2’,3’-d’]anthra[1,2-b:5,6-b’]dithiophene (DNADT) Derivatives: Effect of Alkyl Chains on Transistor Properties International Journal of Molecular Sciences doi: 10.3390/ijms21072447 Authors: Ishida Sawanaka Toyama Ji Mori Nishihara To investigate organic field-effect transistor (OFET) properties, a new thienoacene-type molecule, 4,14-dihexyldinaphtho[2,3-d:2’,3’-d’]anthra[1,2-b:5,6-b’]dithiophene...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2451: Silver Island Film for Enhancing Light Harvesting in Natural Photosynthetic Proteins International Journal of Molecular Sciences doi: 10.3390/ijms21072451 Authors: Kowalska Szalkowski Sulowska Buczynska Niedziolka-Jonsson Jonsson-Niedziolka Kargul Lokstein Mackowski The effects of combining naturally evolved photosynthetic pigment–protein complexes with inorganic functional materials, especially plasmonically active...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2446: Stearoyl-CoA Desaturase is Essential for Porcine Adipocyte Differentiation International Journal of Molecular Sciences doi: 10.3390/ijms21072446 Authors: Liu Wang Liang Wu Liu Yang Tao Zhang Tian Zhao Wang Fat deposition, which influences pork production, meat quality and growth efficiency, is an economically important trait in pigs. Numerous studies have demonstrated that stearoyl-CoA desaturase (SCD), a key enzyme...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2453: Osmunda japonica Extract Suppresses Pro-Inflammatory Cytokines by Downregulating NF-κB Activation in Periodontal Ligament Fibroblasts Infected with Oral Pathogenic Bacteria International Journal of Molecular Sciences doi: 10.3390/ijms21072453 Authors: Jihyoun Seong Jinkyung Lee Yun Kyong Lim Weon-Jong Yoon Seunggon Jung Joong-Ki Kook Tae-Hoon Lee Periodontal diseases are caused by bacterial infection and may progress to chronic dental disease;...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2444: Exploratory Analysis of Circulating miRNA Signatures in Atrial Fibrillation Patients Determining Potential Biomarkers to Support Decision-Making in Anticoagulation and Catheter Ablation International Journal of Molecular Sciences doi: 10.3390/ijms21072444 Authors: Naoki Kiyosawa Kenji Watanabe Yoshiyuki Morishima Takeshi Yamashita Naoharu Yagi Takuto Arita Takayuki Otsuka Shinya Suzuki Novel biomarkers are desired to improve risk management...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2443: Caffeine and Cisplatin Effectively Targets the Metabolism of a Triple-Negative Breast Cancer Cell Line Assessed via Phasor-FLIM International Journal of Molecular Sciences doi: 10.3390/ijms21072443 Authors: Stephanie M. Pascua Gabrielle E. McGahey Ning Ma Justin J. Wang Michelle A. Digman Triple-negative tumor cells, a malignant subtype of breast cancer, lack a biologically targeted therapy. Given its DNA repair inhibiting properties, caffeine has...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2442: Characterization of Carbonic Anhydrase In Vivo Using Magnetic Resonance Spectroscopy International Journal of Molecular Sciences doi: 10.3390/ijms21072442 Authors: Jyoti Singh Tomar Jun Shen Carbonic anhydrase is a ubiquitous metalloenzyme that catalyzes the reversible interconversion of CO2/HCO3−. Equilibrium of these species is maintained by the action of carbonic anhydrase. Recent advances in magnetic resonance spectroscopy have allowed, for...
Wed Apr 01, 2020 03:00
IJMS, Vol. 21, Pages 2441: Structural and Functional Analysis of PGRP-LC Indicates Exclusive Dap-Type PGN Binding in Bumblebees International Journal of Molecular Sciences doi: 10.3390/ijms21072441 Authors: Yanjie Liu Nanhui Ye Minming Chen Huiyue Zhao Jiandong An Peptidoglycan recognition proteins (PGRPs) play an important role in the defense against invading microbes via the recognition of the immunogenic substance peptidoglycan (PGN). Bees possess fewer PGRPs than Drosophila...
Wed Apr 01, 2020 03:00
IJNS, Vol. 6, Pages 30: The Timely Needs for Infantile Onset Pompe Disease Newborn Screening—Practice in Taiwan International Journal of Neonatal Screening doi: 10.3390/ijns6020030 Authors: Chiang Chien Chang Lee Hwu Pompe disease Newborn screening (NBS) aims at diagnosing patients with infantile-onset Pompe disease (IOPD) early enough so a timely treatment can be instituted. Since 2015, the National Taiwan University NBS Center has changed the method for Pompe disease...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 985: Implementing Supported Self-Management in Community-Based Stroke Care: A Secondary Analysis of Nurses’ Perspectives Journal of Clinical Medicine doi: 10.3390/jcm9040985 Authors: Kidd Booth Lawrence Rowat The provision of supported self-management (SSM) is recommended in contemporary guidelines to address the longer-term needs and outcomes of stroke survivors and their families, yet its implementation across stroke pathways has been inconsistent. This...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 986: Executive Functions and Emotion Regulation in Attention-Deficit/Hyperactivity Disorder and Borderline Intellectual Disability Journal of Clinical Medicine doi: 10.3390/jcm9040986 Authors: Predescu Sipos Costescu Ciocan Rus The main objective of this study is to investigate the multiple relations and to determine the differences between executive functions (EFs), emotion regulation, and behavioral and emotional problems in children with attention-deficit/hyperactivity...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 983: Combined DNase and Proteinase Treatment Interferes with Composition and Structural Integrity of Multispecies Oral Biofilms Journal of Clinical Medicine doi: 10.3390/jcm9040983 Authors: Karygianni Attin Thurnheer Modification of oral biofilms adhering to dental hard tissues could lead to new treatment approaches in cariology and periodontology. In this study the impact of DNase I and/or proteinase K on the formation of a simulated supragingival biofilm...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 984: Wound Lavage in Studies on Vital Pulp Therapy of Permanent Teeth with Carious Exposures: A Qualitative Systematic Review Journal of Clinical Medicine doi: 10.3390/jcm9040984 Authors: Munir Zehnder Rechenberg The aim of this study was to systematically review pulp wound lavage in vital pulp therapy (VPT). A search was conducted in six life science databases to identify clinical trials carried out on permanent teeth with a carious pulp exposure and a recall...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 982: Master Regulator Analysis of the SARS-CoV-2/Human Interactome Journal of Clinical Medicine doi: 10.3390/jcm9040982 Authors: Guzzi Mercatelli Ceraolo Giorgi The recent epidemic outbreak of a novel human coronavirus called SARS-CoV-2 causing the respiratory tract disease COVID-19 has reached worldwide resonance and a global effort is being undertaken to characterize the molecular features and evolutionary origins of this virus. In this paper, we set...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 988: Increased Sensitivity of PBMCs Isolated from Patients with Rheumatoid Arthritis to DNA Damaging Agents Is Connected with Inefficient DNA Repair Journal of Clinical Medicine doi: 10.3390/jcm9040988 Authors: Galita Brzezińska Gulbas Sarnik Poplawska Makowska Poplawski Rheumatoid arthritis (RA) is a systemic, inflammatory disease of the joints and surrounding tissues. RA manifests itself with severe joint pain, articular inflammation, and...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 978: Possible Role of Mitochondrial DNA Mutations in Chronification of Inflammation: Focus on Atherosclerosis Journal of Clinical Medicine doi: 10.3390/jcm9040978 Authors: Alexander N. Orekhov Nikita N. Nikiforov Ekaterina A. Ivanova Igor A. Sobenin Chronification of inflammation is the process that lies at the basis of several human diseases that make up to 80% of morbidity and mortality worldwide. It can also explain a great deal of processes related to...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 979: Quantitative Susceptibility Mapping and Vessel Wall Imaging as Screening Tools to Detect Microbleed in Sentinel Headache Journal of Clinical Medicine doi: 10.3390/jcm9040979 Authors: Ishii Nakagawa Zanaty Roa Kasab Shaban Hudson Osorno-Cruz Byer Allan Torner Awad Carroll Samaniego Hasan Background: MR-quantitative susceptibility mapping (QSM) can identify microbleeds (MBs) in intracranial aneurysm (IA) wall...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 980: Fully Digital Workflow for Planning Static Guided Implant Surgery: A Prospective Accuracy Study Journal of Clinical Medicine doi: 10.3390/jcm9040980 Authors: Lin Wu Huang Huang Cheng Wang The accuracy of static guided implant surgery (sGIS) using conventional planning workflow has been extensively examined; however, more information is required to justify the application of fully digital planning protocol. The purpose of this study was to...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 981: Transforaminal Epidural Balloon Adhesiolysis via a Contralateral Interlaminar Retrograde Foraminal Approach: A Retrospective Analysis and Technical Considerations Journal of Clinical Medicine doi: 10.3390/jcm9040981 Authors: Kim Moon Kim Hyun Son Shin Kim Choi Karm Several treatment modalities have been proposed for foraminal stenosis, but the treatment options remain unsatisfactory. Previous studies have shown that transforaminal...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 977: A Randomized Controlled Trial Comparing Novel Triple-Cuffed Double-Lumen Endobronchial Tubes with Conventional Double-Lumen Endobronchial Tubes for Lung Isolation Journal of Clinical Medicine doi: 10.3390/jcm9040977 Authors: Namo Kim Hyo-Jin Byon Go Eun Kim Chungon Park Young Eun Joe Sung Min Suh Young Jun Oh Placing a double-lumen endobronchial tube (DLT) in an appropriate position to facilitate lung isolation is essential for thoracic procedures....
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 976: A Longitudinal Study of the Antioxidant Barrier and Oxidative Stress in Morbidly Obese Patients after Bariatric Surgery. Does the Metabolic Syndrome Affect the Redox Homeostasis of Obese People? Journal of Clinical Medicine doi: 10.3390/jcm9040976 Authors: Choromańska Myśliwiec Łuba Wojskowicz Dadan Myśliwiec Choromańska Zalewska Maciejczyk This is the first study to evaluate both the antioxidant barrier, glutathione metabolism,...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 975: Interhemispheric Functional Connectivity in the Primary Motor Cortex Assessed by Resting-State Functional Magnetic Resonance Imaging Aids Long-Term Recovery Prediction among Subacute Stroke Patients with Severe Hand Weakness Journal of Clinical Medicine doi: 10.3390/jcm9040975 Authors: Min Park Park Kim Cha Gwak Jung Chang Jung This study aimed to evaluate the usefulness of interhemispheric functional connectivity (FC) as a predictor...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 973: Arthroscopy-Assisted Corrective Osteotomy, Reduction, Internal Fixation and Strut Allograft Augmentation for Tibial Plateau Malunion or Nonunion Journal of Clinical Medicine doi: 10.3390/jcm9040973 Authors: Wang Cheng Chen Chan Purpose: The purpose of this study was to present the results of arthroscopy-assisted corrective osteotomy (AACO), reduction, internal fixation, and strut allograft augmentation for tibial plateau malunion or nonunion. Methods:...
Wed Apr 01, 2020 03:00
JCM, Vol. 9, Pages 974: The Outcome of Distal Radius Fractures with Concomitant Injuries Is Similar to those of Isolated Distal Radius Fractures Provided that an Arthroscopically Supported Treatment is Performed Journal of Clinical Medicine doi: 10.3390/jcm9040974 Authors: Von Matthey Schmid Zyskowski Deiler Biberthaler Vester Background: Concomitant injuries of distal radius fractures (DRF) can have a fatal impact on the patients’ outcome. However, wrist...
Wed Apr 01, 2020 03:00
JDB, Vol. 8, Pages 9: Gbx1 and Gbx2 Are Essential for Normal Patterning and Development of Interneurons and Motor Neurons in the Embryonic Spinal Cord Journal of Developmental Biology doi: 10.3390/jdb8020009 Authors: Buckley Burroughs-Garcia Kriks Lewandoski Waters The molecular mechanisms regulating neurogenesis involve the control of gene expression by transcription factors. Gbx1 and Gbx2, two members of the Gbx family of homeodomain-containing transcription factors,...
Wed Apr 01, 2020 03:00
JFB, Vol. 11, Pages 21: Properties and Skin Compatibility of Films Based on Poly(Lactic Acid) (PLA) Bionanocomposites Incorporating Chitin Nanofibrils (CN) Journal of Functional Biomaterials doi: 10.3390/jfb11020021 Authors: Coltelli Aliotta Vannozzi Morganti Panariello Danti Neri Fernandez-Avila Fusco Donnarumma Lazzeri Nanobiocomposites suitable for preparing skin compatible films by flat die extrusion were prepared by using plasticized poly(lactic...
Wed Apr 01, 2020 03:00
J. Imaging, Vol. 6, Pages 17: Evaluation of Automatic Facial Wrinkle Detection Algorithms Journal of Imaging doi: 10.3390/jimaging6040017 Authors: Remah Mutasim Elbashir Moi Hoon Yap Facial wrinkles (considered to be natural features) appear as people get older. Wrinkle detection is an important aspect of applications that depend on facial skin changes, such as face age estimation and soft biometrics. While existing wrinkle detection algorithms focus on forehead horizontal lines,...
Wed Apr 01, 2020 03:00
Medicina, Vol. 56, Pages 158: EMS-effect of Exercises with Music on Fatness and Biomarkers of Obese Elderly Women Medicina doi: 10.3390/medicina56040158 Authors: Jiyoun Kim Yongseok Jee Background and objectives: Electromyostimulation (EMS) has been shown to improve body composition, but what biomarkers it affects has not been investigated. The purpose of this study was to compare the EMS-effect of exercises with music on fatness and biomarker levels in obese elderly. Materials and...
Wed Apr 01, 2020 03:00
Medicina, Vol. 56, Pages 157: Factors that Decrease Sedentary Behavior in Community-Dwelling Elderly People: A Longitudinal Study Medicina doi: 10.3390/medicina56040157 Authors: Owari Background and objectives: This study was to clarify how the frequency of participation in a health class affected the reduction in sedentary behavior after two years, and whether decreases in sedentary behavior in elderly people who participated in a health class persisted two years after the end of an...
Wed Apr 01, 2020 03:00
Medicina, Vol. 56, Pages 156: Comparison of Post-Exercise Hypotension Responses in Paralympic Powerlifting Athletes after Completing Two Bench Press Training Intensities Medicina doi: 10.3390/medicina56040156 Authors: Ângelo de Almeida Paz Felipe José Aidar Dihogo Gama de Matos Raphael Fabrício de Souza Marzo Edir da Silva-Grigoletto Roland van den Tillaar Rodrigo Ramirez-Campillo Fábio Yuzo Nakamura Manoel da Cunha Costa Albená Nunes-Silva Anselmo de Athayde...
Wed Apr 01, 2020 03:00
Metabolites, Vol. 10, Pages 138: Nicotinic Acid Improves Endurance Performance of Mice Subjected to Treadmill Exercise Metabolites doi: 10.3390/metabo10040138 Authors: Ringseis Gessner Beer Albrecht Wen Most Krüger Eder Recently, administration of nicotinic acid (NA) at a pharmacological dose was found to induce a similar change in the muscle´s contractile and metabolic phenotype as observed in response to endurance exercise. Thus, the hypothesis...
Wed Apr 01, 2020 03:00
Metabolites, Vol. 10, Pages 137: Component Profiling of Soy-Sauce-Like Seasoning Produced from Different Raw Materials Metabolites doi: 10.3390/metabo10040137 Authors: Tomoyuki Yamana Moyu Taniguchi Takeharu Nakahara Yusuke Ito Natsuki Okochi Sastia Prama Putri Eiichiro Fukusaki Soy sauce is a traditional Japanese umami seasoning commonly made from soybeans, wheat, and salt water. Soy-sauce-like seasoning, made from other raw materials, such as rice and peas, has recently...
Wed Apr 01, 2020 03:00
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