Publication date: Available online 31 March 2020Source: GeneAuthor(s): Tong Yang, Wan-Xi Yang
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Publication date: Available online 31 March 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Mana Espahbodi, Samantha Kallenbach, Chiang-Ching Huang, Robert H. Chun, Michael E. McCormick
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Publication date: Available online 31 March 2020Source: Journal of Infection and ChemotherapyAuthor(s): Dandan Wu, Haiping Wang, Feiteng Zhu, Shengnan Jiang, Lu Sun, Feng Zhao, Yunsong Yu, Yan Chen
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Related ArticlesExecutive summary of EPOS 2020 including integrated care pathways. Rhinology. 2020 Mar 30;: Authors: Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, Toppila-Salmi S, Bernal-Sprekelsen M, Mullol J Abstract The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012(1-3). The core objective of the EPOS2020 guideline is to...
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Abstract The secretome of Trichoderma reesei contains a mixture of cellulases, hemicellulases, amylases, proteases, and lipases that synergistically degrade plant biomass. Trichodermapepsin (TrAsP), the most prominent protease of T. reesei, affects the stability of cellulases. Similar to cellulase production, TrAsP production also depends on carbon and nitrogen sources. Unlike the cellulase mechanism, the regulatory mechanism of TrAsP remains unknown. Therefore, this study aimed...
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Abstract Water and sediment have always been closely tied in aquatic systems. However, little information regarding the full extent of microeukaryotic composition in both the two habitats did we know especially in estuaries. In the present study, the microeukaryotic abundance, diversity, composition, and their response to environmental factors between sediment and water in the Yellow River Estuary (YRE) were investigated. The microeukaryotic 18S rRNA gene abundance ranged from...
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Related ArticlesCost Effectiveness of Endoscopic Polypectomy in Clinic (EPIC) Compared to Endoscopic Sinus Surgery (ESS): A Modelling Study. Clin Otolaryngol. 2020 Mar 30;: Authors: Kumar S, Thavorn K, van Katwyk S, Lasso A, Kilty S Abstract OBJECTIVE: To compare costs and quality-adjusted life-years of patients receiving endoscopic polypectomy in the clinic those receiving endoscopic sinus surgery from the perspective of Canada's health system....
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Related ArticlesEGF-induced COX-2 regulates metastasis of head and neck squamous cell carcinoma through upregulation of ANGPTL4. Cancer Sci. 2020 Mar 29;: Authors: Chiang KH, Shieh JM, Shen CJ, Chang TW, Wu PT, Hsu JY, Tsai JP, Chang WC, Chen BK Abstract Epidermal growth factor receptor (EGFR) expression and activation are the major causes of metastasis in cancers such as head and neck squamous cell carcinoma (HNSCC). However, the reciprocal effect...
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Related ArticlesOutcomes of sinonasal mucosal melanomas with endoscopic and open resection: a retrospective cohort study. J Neurooncol. 2020 Mar 29;: Authors: Almutuawa DM, Strohl MP, Gruss C, van Zante A, Yom SS, McDermott MW, El-Sayed IH Abstract PURPOSE: To compare the outcomes of Sinonasal Mucosal Melanomas (SNMM) treated with endoscopic and open resection. METHODS: A retrospective case review of 20 patients with SNMM treated surgically...
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Related ArticlesRSRC1 loss-of-function variants cause mild to moderate autosomal recessive intellectual disability. Brain. 2020 Mar 30;: Authors: Scala M, Mojarrad M, Riazuddin S, Brigatti KW, Ammous Z, Cohen JS, Hosny H, Usmani MA, Shahzad M, Riazuddin S, Stanley V, Eslahi A, Person RE, Elbendary HM, Comi AM, Poskitt L, Salpietro V, Genomics QS, Rosenfeld JA, Williams KB, Marafi D, Xia F, Biderman Waberski M, Zaki MS, Gleeson J, Puffenberger E, Houlden H, Maroofian...
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Related ArticlesLHPP inhibits cell growth and migration and triggers autophagy in papillary thyroid cancer by regulating the AKT/AMPK/mTOR signaling pathway. Acta Biochim Biophys Sin (Shanghai). 2020 Mar 30;: Authors: Sun W, Qian K, Guo K, Chen L, Xiang J, Li D, Wu Y, Ji Q, Sun T, Wang Z Abstract In recent decades, the incidence rate of papillary thyroid carcinoma (PTC) has been rapidly increasing. However, the molecular mechanism of the physiological...
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Related ArticlesAnalysis of dose using CBCT and synthetic CT during head and neck radiotherapy: A single centre feasibility study. Tech Innov Patient Support Radiat Oncol. 2020 Jun;14:21-29 Authors: Hay LK, Paterson C, McLoone P, Miguel-Chumacero E, Valentine R, Currie S, Grose D, Schipani S, Wilson C, Nixon I, James A, Duffton A Abstract Objectives: The study aimed to assess the suitability of deformable image registration (DIR) software to generate...
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Related ArticlesThe Landscape of Somatic Copy Number Alterations in Head and Neck Squamous Cell Carcinoma. Front Oncol. 2020;10:321 Authors: Yang J, Chen Y, Luo H, Cai H Abstract Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide. Somatic copy number alterations (CNAs) play a significant role in the development of this lethal cancer. In this study, we present a meta-analysis of CNAs for a total of 1,395 HNSCC...
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Related ArticlesRadiotherapy Quality Assurance for Head and Neck Squamous Cell Carcinoma. Front Oncol. 2020;10:282 Authors: Van Gestel D, Dragan T, Grégoire V, Evans M, Budach V Abstract The impact of radiotherapy (RT) quality assurance (QA) has been demonstrated by numerous studies and is particularly important for head and neck cancer (HNC) treatment due to the complexity of RT target volumes in this region and the multiple adjacent organs at risk....
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Related ArticlesTriple Head and Neck Carcinoma: Case Report and Literature Review. Cureus. 2020 Feb 23;12(2):e7082 Authors: I Awad B, Melibari B, Safadi N, Al-Garni M, Al-Hakami HA Abstract Synchronous cancers are multiple cancers that develop within six months of the initial diagnosis while metachronous cancers are those that develop more than six months after the initial diagnosis. A combination of three cancers is seen with several patients, which...
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Related ArticlesFluorescence-guided imaging for resection margin evaluation in head and neck cancer patients using cetuximab-800CW: A quantitative dose-escalation study. Theranostics. 2020;10(9):3994-4005 Authors: Voskuil FJ, de Jongh SJ, Hooghiemstra WTR, Linssen MD, Steinkamp PJ, de Visscher SAHJ, Schepman KP, Elias SG, Meersma GJ, Jonker PKC, Doff JJ, Jorritsma-Smit A, Nagengast WB, van der Vegt B, Robinson DJ, van Dam GM, Witjes MJH Abstract ...
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Related ArticlesWhy Italian ENT physicians should be aware of SARS-CoV-2. Acta Otorhinolaryngol Ital. 2020 Mar 31;: Authors: Torretta S, Gaini LM, Pignataro L PMID: 32225995 [PubMed - as supplied by publisher]
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Related ArticlesChoanal Polyp with Osseous Metaplasia: Radiological and Therapeutic Management of a Rare Case and a Review of Bone Metaplastic Lesions of Sinonasal Tract. Am J Case Rep. 2020 Mar 30;21:e921494 Authors: Testa D, Nunziata M, Romano ML, Massimilla EA, Toni G, De Cristofaro G, Marcuccio G, Motta G Abstract BACKGROUND Osseous metaplasia is a heterotopic normal bone in soft tissues. It is occasionally found in mucosal polyps of the external...
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Related ArticlesLuteolin-7-O-Glucoside Inhibits Oral Cancer Cell Migration and Invasion by Regulating Matrix Metalloproteinase-2 Expression and Extracellular Signal-Regulated Kinase Pathway. Biomolecules. 2020 Mar 26;10(4): Authors: Velmurugan BK, Lin JT, Mahalakshmi B, Chuang YC, Lin CC, Lo YS, Hsieh MJ, Chen MK Abstract Oral squamous cell carcinoma is the sixth most common type of cancer globally, which is associated with high rates of cancer-related...
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Related ArticlesAnalysis of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas and Paired Normal Mucosae Reveals Cyclin D1 Deregulation and Compensatory Effect of Cyclin D2. Cancers (Basel). 2020 Mar 26;12(4): Authors: Novotný J, Bandúrová V, Strnad H, Chovanec M, Hradilová M, Šáchová J, Šteffl M, Grušanović J, Kodet R, Pačes V, Lacina L, Jr KS, Plzák J, Kolář M, Vomastek T Abstract Aberrant regulation of the cell cycle is a typical...
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Related ArticlesMicrosurgery for Head and Neck Reconstruction. J Craniofac Surg. 2020 Mar 27;: Authors: Onoda S, Masahito K Abstract The most serious complication of free flap transfer is total flap necrosis, which is usually due to a microvascular problem. The development of a microsurgical instrument has greatly lowered the prevalence of postoperative vascular trouble to a rate of 1% to 3%. However, necrosis of the transferred flap in head and...
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Related ArticlesDelayed Traumatic Pseudoaneurysm of the Dorsal Nasal Artery. J Craniofac Surg. 2020 Mar 27;: Authors: Kim TH, Lim EJ, Kim S, Park JH Abstract A pseudoaneurysm is an uncommon pathology arising from any artery in the human body. It typically presents as a pulsatile swelling in contact with a blood vessel. Of pseudoaneurysms of the head and neck region, the most common site is the superficial temporal artery while that of the dorsal...
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Related ArticlesThe Efficacy of Surgical Excision Plus Adjuvant Multimodal Therapies in the Treatment of Keloids: A Systematic Review and Meta-Analysis. Dermatol Surg. 2020 Mar 27;: Authors: Ellis MM, Jones LR, Siddiqui F, Sunkara PR, Ozog DM Abstract BACKGROUND: Research evaluating the efficacy of multimodal therapy for the treatment of keloids has reported combination regimens are most effective. OBJECTIVE: To compare recurrence rates...
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Related ArticlesWild-type IDH2 contributes to Epstein-Barr virus-dependent metabolic alterations and tumorigenesis. Mol Metab. 2020 Feb 18;36:100966 Authors: Shi F, He Y, Li J, Tang M, Li Y, Xie L, Zhao L, Hu J, Luo X, Zhou M, Liu N, Fan J, Zhou J, Gao Q, Qiu S, Wu W, Zhang X, Jia W, Bode AM, Cao Y Abstract OBJECTIVE: Epstein-Barr virus (EBV) is a well-recognized oncogenic virus that can induce host cell metabolic reprogramming and tumorigenesis...
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Related ArticlesImplementation of auricular malformation screenings in the newborn population. Int J Pediatr Otorhinolaryngol. 2020 Mar 12;133:109999 Authors: Liu YC, Kini S, Barton G, Pham T, Marcet-Gonzalez J, Novak B Abstract BACKGROUND AND OBJECTIVE: Research has shown that it is important to initiate ear molding early for children with auricular malformations in order to achieve the best results. Currently our institute relies on the traditional...
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Related ArticlesStepwise-activatable hypoxia triggered nanocarrier-based photodynamic therapy for effective synergistic bioreductive chemotherapy. Biomaterials. 2020 Mar 18;245:119982 Authors: Ihsanullah KM, Kumar BN, Zhao Y, Muhammad H, Liu Y, Wang L, Liu H, Jiang W Abstract Tumor cell populations are highly heterogeneous, which limit the homogeneous distribution and optimal delivery of nanomedicines, thereby inducing insufficient therapeutic benefits....
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Related ArticlesProton therapy for head and neck squamous cell carcinomas: A review of the physical and clinical challenges. Radiother Oncol. 2020 Mar 27;147:30-39 Authors: Beddok A, Vela A, Calugaru V, Tessonnier T, Kubes J, Dutheil P, Gerard A, Vidal M, Goudjil F, Florescu C, Kammerer E, Benezery K, Herault J, Poortmans P, Bourhis J, Thariat J, GORTEC, the 3 French proton centers Abstract The quality of radiation therapy has been shown to significantly...
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Related ArticlesPrediction of radiation-induced mucositis of H&N cancer patients based on a large patient cohort. Radiother Oncol. 2020 Mar 27;147:15-21 Authors: Hansen CR, Bertelsen A, Zukauskaite R, Johnsen L, Bernchou U, Thwaites DI, Eriksen JG, Johansen J, Brink C Abstract PURPOSE/OBJECTIVE: Radiation-induced mucositis is a severe acute side effect, which can jeopardize treatment compliance and cause weight loss during treatment. The study...
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Related ArticlesHigh-risk human papillomavirus-mediated adenocarcinoma of palatine tonsil. Pathol Res Pract. 2020 Mar 19;:152924 Authors: Alexiev BA, Behdad A, Lu X, Cheng E, Samant S Abstract We describe the case of a human papillomavirus-mediated adenocarcinoma of palatine tonsil in a 51-year-old male. Histologically, the tumor exhibited a predominantly cribriform and tubular (glandular) growth of cuboidal and columnar cells with moderate amount...
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Related ArticlesOptimization of muscle activation schemes in a finite element neck model simulating volunteer frontal impact scenarios. J Biomech. 2020 Mar 16;:109754 Authors: Correia MA, McLachlin SD, Cronin DS Abstract Neck muscle activation is increasingly important for accurate prediction of occupant response in automotive impact scenarios and occupant excursion resulting from active safety systems such as autonomous emergency braking. Muscle...
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Related ArticlesAn unusual presentation of supernumerary teeth in the mastoid bone. Br J Oral Maxillofac Surg. 2020 Mar 26;: Authors: Zhu F, Ma L, He Y, Zhang D PMID: 32224007 [PubMed - as supplied by publisher]
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Related ArticlesInvestigating the use of aperture shape controller in VMAT treatment deliveries. Med Dosim. 2020 Mar 26;: Authors: Binny D, Spalding M, Crowe SB, Jolly D, Kairn T, Trapp JV, Walsh A Abstract BACKGROUND: Aperture shape controller (ASC) is a recently introduced leaf sequencer that controls the complexity of multileaf collimator apertures in the Photon Optimizer algorithm of the Eclipse treatment planning system. The aim of this study...
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Related ArticlesSaliva as a diagnostic tool for dental caries, periodontal disease and cancer: is there a need for more biomarkers? Expert Rev Mol Diagn. 2020 Mar 30;:1-13 Authors: Buzalaf MAR, Ortiz AC, Carvalho TS, Fideles SOM, Araújo TT, Moraes SM, Buzalaf NR, Reis FN Abstract Introduction: A biomarker is a biological indicator of normal or pathogenic processes. Identification of biomarkers is useful for the prevention, diagnosis and prognosis...
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Related ArticlesProspective Qualitative Multidimensional Assessment of the Postoperative Rhinoplasty Experience. Facial Plast Surg Aesthet Med. 2020 Mar 30;: Authors: Gadkaree SK, Shaye DA, McCarty JC, Occhiogrosso J, Spagnuolo G, Derakhshan A, Lee LN Abstract Background: Understanding the multidimensional postoperative patient experience after rhinoplasty is critical for preoperative counseling and postoperative management. Methods: A prospective...
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Related ArticlesCirculating tumour DNA alterations as biomarkers for head and neck cancer: a systematic review. Acta Oncol. 2020 Mar 30;:1-6 Authors: Pall AH, Jakobsen KK, Grønhøj C, von Buchwald C Abstract Background: Head and neck squamous cell carcinoma (HNSCC) is a significant global burden. The development of a diagnostic or recurrence monitoring test could evolve from the exploitation of molecular markers such as tumour-specific DNA alterations...
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Related ArticlesSurvival, Outcomes, and Use of Acuity Scoring Systems Following Tracheotomy in Veteran Patients. Am J Hosp Palliat Care. 2020 Mar 30;:1049909120914518 Authors: Bier-Laning CM, Hotaling J, Canar WJ, Ansari AA Abstract OBJECTIVES: To determine whether established prognosis tools used in the general population of critically ill patients will accurately predict tracheotomy-related outcomes and survival outcomes in critically ill patients...
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Related ArticlesMultidisciplinary Tumor Boards in Dermatologic Surgery. Dermatol Surg. 2019 12;45 Suppl 2:S129-S141 Authors: Chen DL, Cintolo-Gonzalez J, Cook D, Devenney B, Goldman GD, Greene L, Harlow S, Holmes T, Rehman H, Sajisevi M, Anker C Abstract BACKGROUND: Recent advances in diagnostic and therapeutic modalities have made oncologic care ever more challenging, and multidisciplinary tumor boards (MTBs) are increasingly being used as a forum...
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Related ArticlesMohs Surgery for Advanced Tumors of the Scalp. Dermatol Surg. 2019 12;45 Suppl 2:S110-S117 Authors: Yu WY, Salmon P, Thuener J, Bordeaux JS Abstract BACKGROUND: The scalp presents unique surgical challenges, and specialized techniques are sometimes required to achieve optimal results. Tumors arising on the scalp may also be at increased risk of complications such as in-transit metastasis and perineural invasion. OBJECTIVE: To...
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Related ArticlesAcoustic neuroma with orofacial paresthesia: description of an atypical presentation. BMJ Case Rep. 2019 Nov 04;12(11): Authors: Lim CC, Misron K, Liew YT, Wong EHC Abstract Acoustic neuroma (AN) usually manifests with asymmetric hearing loss, tinnitus, dizziness and sense of disequilibrium. About 10% of patients complain of atypical symptoms, which include facial numbness or pain and sudden onset of hearing loss. Patients with atypical...
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