Πέμπτη 19 Σεπτεμβρίου 2019


[ASAP] Bacterial Extracellular Electron Transfer Occurs in Mammalian Gut
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03176
Analytical Chemistry
Wed Sep 18, 2019 07:00
[ASAP] Hybrid 193 nm Ultraviolet Photodissociation Mass Spectrometry Localizes Cardiolipin Unsaturations
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03278
Analytical Chemistry
Wed Sep 18, 2019 07:00
[ASAP] Speciation Analysis of the Uptake and Biodistribution of Nanoparticulate and Ionic Silver in <italic toggle="yes">Escherichia coli</italic>
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03359
Analytical Chemistry
Wed Sep 18, 2019 07:00
Sarcopenic obesity and post‐operative morbidity after pancreatic surgery: a cohort study
Significant variability exists in the sarcopenic indices. All three sarcopenic indices previously described failed to predict post‐operative morbidity. Sarcopenic obesity was the only predictor of post‐operative morbidity. Abstract Background Several indices of sarcopenia (SARC) exist in the literature, however, there is no consensus as to the best SARC index to predict post‐operative morbidity following pancreatic surgery. Methods A prospectively collected database was reviewed in...
ANZ Journal of Surgery
Wed Sep 18, 2019 14:53
Caecal herniation and volvulus through the foramen of Winslow: a rare presentation
ANZ Journal of Surgery
Wed Sep 18, 2019 14:54
Concurrent gallstone ileus and cholecystocolic fistula causing high volume diarrhoea
ANZ Journal of Surgery
Wed Sep 18, 2019 14:54
Intussusception of terminal ileum into cecum associated with endometriosis
ANZ Journal of Surgery
Wed Sep 18, 2019 14:54
PD-1/PD-L1 Immune-Checkpoint Inhibition with Radiation in Bladder Cancer: In Situ and Abscopal Effects
The combination of radiation with immune-checkpoint inhibitors was reported in some cancers to have synergic effects both locally and distally. Our aim was to assess this combined therapy on both radiated and non-radiated bladder tumors and to characterize the immune landscape within the tumor microenvironment. Murine bladder cancer cells (MB49) were injected s.c. in both flanks of C57BL/6 mice. Mice were randomly assigned to the following treatments: placebo, antiPD-L1 (4 intra-peritoneal injections...
Molecular Cancer Therapeutics Online First Articles
Wed Sep 18, 2019 20:44
Predictive and Pharmacodynamic Biomarkers of Response to the Phosphatidylinositol 3-Kinase Inhibitor Taselisib in Breast Cancer Preclinical Models
The phosphatidylinositol 3-kinase (PI3K) signaling pathway serves as a central node in regulating cell survival, proliferation and metabolism. PIK3CA, the gene encoding the PI3K catalytic subunit p110-alpha, is commonly altered in breast cancer resulting in the constitutive activation of the PI3K pathway. Using an unbiased cell line screening approach, we tested the sensitivity of breast cancer cell lines to taselisib, a potent PI3K inhibitor, and correlated sensitivity with key biomarkers (PIK3CA,...
Molecular Cancer Therapeutics Online First Articles
Wed Sep 18, 2019 20:44
Pharmacology of the ATM inhibitor AZD0156: potentiation of irradiation and olaparib responses pre-clinically.
AZD0156 is a potent and selective, bio-available inhibitor of Ataxia Telangiectasia Mutated (ATM) protein, a signaling kinase involved in the DNA damage response (DDR). We present pre-clinical data demonstrating abrogation of irradiation-induced ATM signaling by low doses of AZD0156, as measured by phosphorylation of ATM substrates. AZD0156 is a strong radio-sensitizer in vitro, and using a lung xenograft model, we show that systemic delivery of AZD0156 enhances the tumor growth inhibitory effects...
Molecular Cancer Therapeutics Online First Articles
Wed Sep 18, 2019 20:44
ALDH1A1 contributes to PARP inhibitor resistance via enhancing DNA repair in BRCA2-/- ovarian cancer cells
Poly (ADP-ribose) Polymerase (PARP) inhibitors (PARPi) are approved to treat recurrent ovarian cancer with BRCA1 or BRCA2 mutations, and as maintenance therapy for recurrent platinum sensitive ovarian cancer (BRCA wild-type or mutated) after treatment with platinum. However, the acquired resistance against PARPi remains a clinical hurdle. Here, we demonstrated that PARP inhibitor (olaparib)-resistant epithelial ovarian cancer (EOC) cells exhibited an elevated aldehyde dehydrogenase (ALDH) activity,...
Molecular Cancer Therapeutics Online First Articles
Wed Sep 18, 2019 20:44
Jonathan R. Warner- Pioneer of Ribosome Synthesis [Article]
No abstract.
RNA In Advance
Wed Sep 18, 2019 21:23
Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a predominantly fatal common malignancy with inadequate treatment options. Glycogen synthase kinase 3β (GSK-3β) is an emerging target in human malignancies including PDAC.Experimental Design: Pancreatic cancer cell lines and patient-derived xenografts were treated with a novel GSK-3 inhibitor 9-ING-41 alone or in combination with chemotherapy. Activation of the DNA damage response pathway and S-phase arrest induced by gemcitabine were assessed in...
Clinical Cancer Research Online First Articles
Wed Sep 18, 2019 17:00
Visualization and Quantification of Transposon Activity in Caenorhabditis elegans RNAi Pathway Mutants
RNA silencing pathways play critical roles in maintaining quiescence of transposons in germ cells to promote genome integrity. However the precise mechanism by which different types of transposons are recognized by these pathways is not fully understood. Furthermore, the location in the germline where this transposition occurs after disruption of transposon silencing was previously unknown. Here we utilize the spatial and temporal organization of the Caenorhabditis elegans germline to demonstrate...
G3: .Genes, Genomes, Genetics Mission - Online First Articles
00:45
Benchmarking Parametric and Machine Learning Models for Genomic Prediction of Complex Traits
The usefulness of genomic prediction in crop and livestock breeding programs has prompted efforts to develop new and improved genomic prediction algorithms, such as artificial neural networks and gradient tree boosting. However, the performance of these algorithms has not been compared in a systematic manner using a wide range of datasets and models. Using data of 18 traits across six plant species with different marker densities and training population sizes, we compared the performance of six linear...
G3: .Genes, Genomes, Genetics Mission - Online First Articles
00:45
Satellites in the prokaryote world
Satellites or tandem repeats are very abundant in many eukaryotic genomes. Occasionally they have been reported to be present in some prokaryotes, but to our knowledge there is no general comparative study on ...
BMC Evolutionary Biology - Latest Articles
Wed Sep 18, 2019 03:00
Virulence structure and its genetic diversity analyses of Blumeria graminis f. sp. tritici isolates in China
Blumeria graminis f. sp. tritici (Bgt), the causal agent of wheat powdery mildew severely affects yield security wheat production in China. Understanding the virulence structure and genetic variations of this pat...
BMC Evolutionary Biology - Latest Articles
Wed Sep 18, 2019 03:00
Phylogenomics resolves major relationships and reveals significant diversification rate shifts in the evolution of silk moths and relatives
Silkmoths and their relatives constitute the ecologically and taxonomically diverse superfamily Bombycoidea, which includes some of the most charismatic species of Lepidoptera. Despite displaying spectacular f...
BMC Evolutionary Biology - Latest Articles
Wed Sep 18, 2019 03:00
A newly discovered radiation of endoparasitic gastropods and their coevolution with asteroid hosts in Antarctica
Marine invertebrates are abundant and diverse on the continental shelf in Antarctica, but little is known about their parasitic counterparts. Endoparasites are especially understudied because they often posses...
BMC Evolutionary Biology - Latest Articles
Wed Sep 18, 2019 03:00
Evaluation of platelet distribution width as a diagnostic and prognostic biomarker in bladder neoplasm
Future Oncology, Ahead of Print.
Future Oncology
Wed Sep 18, 2019 06:24
Delineating Astrocytic Cytokine Responses in a Human Stem Cell Model of Neural Trauma
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Sep 18, 2019 10:00
Protein Tyrosine Phosphatase σ Inhibitory Peptide Promotes Recovery of Diaphragm Function and Sprouting of Bulbospinal Respiratory Axons after Cervical Spinal Cord Injury
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Sep 18, 2019 10:00
Machine Learning to Predict In-Hospital Morbidity and Mortality after Traumatic Brain Injury
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Sep 18, 2019 10:00
Resting-State fMRI Metrics in Acute Sport-Related Concussion and Their Association with Clinical Recovery: A Study from the NCAA-DOD CARE Consortium
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Sep 18, 2019 10:00
Depletion of Microglia Attenuates Dendritic Spine Loss and Neuronal Apoptosis in the Acute Stage of Moderate Traumatic Brain Injury in Mice
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Sep 18, 2019 10:00
Association between History of Concussion and Substance Use Is Mediated by Mood Disorders
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Sep 18, 2019 10:00
TMEM176A and TMEM176B Are Candidate Regulators of Inhibition of Dendritic Cell Maturation and Function after Chronic Spinal Cord Injury
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Sep 18, 2019 10:00
Different Vibratory Conditions Elicit Different Structural and Biological Vocal Fold Changes in an In-Vivo Rabbit Model of Phonation
Vibration of the vocal folds can disrupt the tissue and induce structural, functional, and molecular changes; the presence or absence of contact between the vocal folds during vibration can affect the type and extent of these changes. The purpose of this study was to characterize vocal fold changes following 2 hours of contact phonation or phonation without vibratory contact.
Journal of Voice
Wed Sep 18, 2019 03:00
Calendar Listings
Journal of Voice
Sun Sep 01, 2019 03:00
Editorial Board
Journal of Voice
Sun Sep 01, 2019 03:00
Calendar
Journal of Voice
Sun Sep 01, 2019 03:00
TOC
Journal of Voice
Sun Sep 01, 2019 03:00
Instructions for Contributors
Journal of Voice
Sun Sep 01, 2019 03:00
The Behavior of Tendon Progenitor Cells from Tendinopathic Tendons: Implications for Treatment
Tissue Engineering Part A, Ahead of Print.
Tissue Engineering
Wed Sep 18, 2019 10:00
Development of a Rat Liver Machine Perfusion System for Normothermic and Subnormothermic Conditions
Tissue Engineering Part A, Ahead of Print.
Tissue Engineering
Wed Sep 18, 2019 10:00
Maternal Thyroid Function in Early Pregnancy and Child Attention-Deficit Hyperactivity Disorder: An Individual-Participant Meta-Analysis
Thyroid, Volume 29, Issue 9, Page 1316-1326, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00
Correction to: Reduced Sensitivity to Thyroid Hormone as a Transgenerational Epigenetic Marker Transmitted Along the Human Male Line by Anselmo J, Scherberg NH, Dumitrescu AM, Refetoff S. Thyroid 2019;29:778–782. DOI: 10.1089/thy.2019.0080
Thyroid, Volume 29, Issue 9, Page 1346-1346, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00
Clinical, Pathological, and Molecular Profiling of Radioactive Iodine Refractory Differentiated Thyroid Cancer
Thyroid, Volume 29, Issue 9, Page 1262-1268, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00
Prognostic Significance of Extent of Invasion in Poorly Differentiated Thyroid Carcinoma
Thyroid, Volume 29, Issue 9, Page 1255-1261, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00

Nonalcoholic Fatty Liver Disease and Hypercholesterolemia: Roles of Thyroid Hormones, Metabolites, and Agonists
Thyroid, Volume 29, Issue 9, Page 1173-1191, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00
Fingolimod Improves the Outcome of Experimental Graves' Disease and Associated Orbitopathy by Modulating the Autoimmune Response to the Thyroid-Stimulating Hormone Receptor
Thyroid, Volume 29, Issue 9, Page 1286-1301, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00
Molecular Testing Versus Diagnostic Lobectomy in Bethesda III/IV Thyroid Nodules: A Cost-Effectiveness Analysis
Thyroid, Volume 29, Issue 9, Page 1237-1243, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00
Future Meetings
Thyroid, Volume 29, Issue 9, Page 1344-1345, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00
Association of Thyroid Function with Handgrip Strength: Data from the Study of Health in Pomerania and the Berlin Aging Study II
Thyroid, Volume 29, Issue 9, Page 1220-1226, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00
Interaction of Genetic Variations in NFE2L2 and SELENOS Modulates the Risk of Hashimoto's Thyroiditis
Thyroid, Volume 29, Issue 9, Page 1302-1315, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00
Correction to: Wide Spectrum of DUOX2 Deficiency: From Life-Threatening Compressive Goiter in Infancy to Lifelong Euthyroidism by Dufort G, Larrivée-Vanier S, Eugène D, De Deken X, Seebauer B, Heinimann K, Lévesque S, Gravel S, Szinnai G, Van Vliet G, and Deladoëy J. Thyroid 2019;29:1018–1022.
Thyroid, Volume 29, Issue 9, Page 1347-1347, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00
Associations of Elevated Antithyroperoxidase Antibodies with Thyroid Function, Survival, Functioning, and Depressive Symptoms in the Oldest Old: The Leiden 85-plus Study
Thyroid, Volume 29, Issue 9, Page 1201-1208, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00
Characterization of Activating Mutations of the MEK1 Gene in Papillary Thyroid Carcinomas
Thyroid, Volume 29, Issue 9, Page 1279-1285, September 2019.
liebertpub1
Tue Sep 17, 2019 10:00

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