Publication date: October 2019Source: Journal of Human Evolution, Volume 135Author(s): Christopher C. Gilbert, Ramesh K. Sehgal, Kelsey D. Pugh, Christopher J. Campisano, Evangeline May, Biren A. Patel, Ningthoujam Premjit Singh, Rajeev Patnaik
Thu Sep 12, 2019 19:04
Publication date: Available online 11 September 2019Source: Medical Image AnalysisAuthor(s): Nooshin Ghavami, Yipeng Hu, Eli Gibson, Ester Bonmati, Mark Emberton, Caroline M. Moore, Dean C. BarrattAbstractConvolutional neural networks (CNNs) have recently led to significant advances in automatic segmentations of anatomical structures in medical images, and a wide variety of network architectures are now available to the research community. For applications such as segmentation of the prostate in...
Thu Sep 12, 2019 19:13
Journal of International Medical Research, Ahead of Print.
Thu Sep 12, 2019 08:45
Journal of International Medical Research, Ahead of Print.
Thu Sep 12, 2019 09:33
Journal of International Medical Research, Ahead of Print.
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Journal of International Medical Research, Ahead of Print.
Thu Sep 12, 2019 09:59
Journal of International Medical Research, Ahead of Print.
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Journal of International Medical Research, Ahead of Print.
Thu Sep 12, 2019 10:08
Journal of International Medical Research, Ahead of Print.
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Journal of International Medical Research, Ahead of Print.
Thu Sep 12, 2019 10:24
Journal of International Medical Research, Ahead of Print.
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Journal of International Medical Research, Ahead of Print.
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Journal of International Medical Research, Ahead of Print.
Thu Sep 12, 2019 10:49
Journal of International Medical Research, Ahead of Print.
Thu Sep 12, 2019 10:57
Journal of International Medical Research, Ahead of Print.
Thu Sep 12, 2019 11:11
Journal of International Medical Research, Ahead of Print.
Thu Sep 12, 2019 11:18
Journal of International Medical Research, Ahead of Print.
Thu Sep 12, 2019 11:31
Cancers, Vol. 11, Pages 1349: Estrogens Counteract Platinum-Chemosensitivity by Modifying the Subcellular Localization of MDM4 Cancers doi: 10.3390/cancers11091349 Authors: Rossella Lucà Giorgia di Blasio Daniela Gallo Valentina Monteleone Isabella Manni Laura Fici Marianna Buttarelli Germana Ciolli Marsha Pellegrino Emanuela Teveroni Silvia Maiullari Alessandra Ciucci Alessandro Apollo Francesca Mancini Maria Pia Gentileschi Gian Franco Zannoni...
Thu Sep 12, 2019 03:00
Cancers, Vol. 11, Pages 1350: Human Ovarian Cancer Tissue Exhibits Increase of Mitochondrial Biogenesis and Cristae Remodeling Cancers doi: 10.3390/cancers11091350 Authors: Anna Signorile Domenico De Rasmo Antonella Cormio Clara Musicco Roberta Rossi Francesco Fortarezza Luigi Leonardo Palese Vera Loizzi Leonardo Resta Giovanni Scillitani Ettore Cicinelli Francesca Simonetti Anna Ferretta Silvia Russo Antonio Tufaro Gennaro Cormio Ovarian...
Thu Sep 12, 2019 03:00
Cancers, Vol. 11, Pages 1351: Early Steps of Mammary Stem Cell Transformation by Exogenous Signals; Effects of Bisphenol Endocrine Disrupting Chemicals and Bone Morphogenetic Proteins Cancers doi: 10.3390/cancers11091351 Authors: Nora Jung Veronique Maguer-Satta Boris Guyot Estrogens are major regulators of the mammary gland development, notably during puberty, via estrogen receptor (ER) activation, leading to the proliferation and differentiation of mammary cells. In addition...
Thu Sep 12, 2019 03:00
Cancers, Vol. 11, Pages 1354: Purine-Metabolising Enzymes and Apoptosis in Cancer Cancers doi: 10.3390/cancers11091354 Authors: Camici Garcia-Gil Pesi Allegrini Tozzi The enzymes of both de novo and salvage pathways for purine nucleotide synthesis are regulated to meet the demand of nucleic acid precursors during proliferation. Among them, the salvage pathway enzymes seem to play the key role in replenishing the purine pool in dividing and tumour cells that require a...
Thu Sep 12, 2019 03:00
Cancers, Vol. 11, Pages 1353: CYP2D6 Genotype Predicts Plasma Concentrations of Tamoxifen Metabolites in Ethiopian Breast Cancer Patients Cancers doi: 10.3390/cancers11091353 Authors: Jemal Hussien Ahmed Eyasu Makonnen Alan Fotoohi Abraham Aseffa Rawleigh Howe Eleni Aklillu Tamoxifen displays wide inter-individual variability (IIV) in its pharmacokinetics and treatment outcome. Data on tamoxifen pharmacokinetics and pharmacogenetics from black African breast cancer patient...
Thu Sep 12, 2019 03:00
Cancers, Vol. 11, Pages 1352: Growth Hormone Upregulates Melanocyte-Inducing Transcription Factor Expression and Activity via JAK2-STAT5 and SRC Signaling in GH Receptor-Positive Human Melanoma Cancers doi: 10.3390/cancers11091352 Authors: Reetobrata Basu Prateek Kulkarni Yanrong Qian Christopher Walsh Pranay Arora Emily Davis Silvana Duran-Ortiz Kevin Funk Diego Ibarra Colin Kruse Samuel Mathes Todd McHugh Alison Brittain Darlene E. Berryman Edward...
Thu Sep 12, 2019 03:00
Cancers, Vol. 11, Pages 1356: Low Numbers of Vascular Vessels Correlate to Progression in Hormone-Naïve Prostate Carcinomas Undergoing Radical Prostatectomy Cancers doi: 10.3390/cancers11091356 Authors: Smentoch Szade Żaczek Eltze Semjonow Brandt Bednarz-Knoll Vascularization influences tumor development by supporting the nutrition anddissemination of tumor cells. On the other hand, a low number of vascular vessels (VVlow) mayinduce hypoxia, accounting for selection...
Thu Sep 12, 2019 03:00
Cancers, Vol. 11, Pages 1355: Current Treatment Options for Metastatic Hormone-Sensitive Prostate Cancer. Cancers doi: 10.3390/cancers11091355 Authors: Cattrini Castro Lozano Zanardi Rubagotti Boccardo Olmos The possible treatments options for metastatic hormone-sensitive prostate cancer (mHSPC) have dramatically increased during the last years. The old backbone, which androgen-deprivation therapy (ADT) is the exclusive approach for hormone-naïve patients,...
Thu Sep 12, 2019 03:00
Cancers, Vol. 11, Pages 1358: CD123 as a Therapeutic Target in the Treatment of Hematological Malignancies Cancers doi: 10.3390/cancers11091358 Authors: Testa Pelosi Castelli The interleukin-3 receptor alpha chain (IL-3R), more commonly referred to as CD123, is widely overexpressed in various hematological malignancies, including acute myeloid leukemia (AML), B-cell acute lymphoblastic leukemia, hairy cell leukemia, Hodgkin lymphoma and particularly, blastic plasmacytoid dendritic...
Thu Sep 12, 2019 03:00
Cancers, Vol. 11, Pages 1357: Kinase Inhibitors and Ovarian Cancer Cancers doi: 10.3390/cancers11091357 Authors: Katopodis Chudasama Wander Sales Kumar Pandhal Anikin Chatterjee Hall Karteris Ovarian cancer is fifth in the rankings of cancer deaths among women, and accounts for more deaths than any other gynecological malignancy. Despite some improvement in overall-(OS) and progression-free survival (PFS) following surgery and first-line chemotherapy,...
Thu Sep 12, 2019 03:00
This cohort study investigates the association of delayed treatment initiation with overall survival and recurrence among patients with head and neck squamous cell carcinoma among an underserved urban population.
Thu Sep 12, 2019 03:00
This Viewpoint discusses why hearing aids and related services should be covered for all US Medicaid enrollees for whom they are medically necessary, regardless of age.
Thu Sep 12, 2019 03:00
This cohort study uses a Korean nationwide database to investigate whether obstructive sleep apnea is associated with the development of depression and anxiety.
Thu Sep 12, 2019 03:00
Despite aggressive multimodal therapy consisting of combinations of surgery, radiotherapy, and chemotherapy, patients with locally advanced head and neck squamous cell carcinoma (HNSCC) have a poor prognosis, with 5-year survival rates hovering around 50%. This suboptimal survival is even worse for racial/ethnic minorities and underinsured patients with HNSCC, who experience significantly higher rates of mortality relative to their white and well-insured peers. Therefore, HNSCC is a cancer for which...
Thu Sep 12, 2019 03:00
A 29-year-old man with a history of aplastic anemia who was being treated with cyclosporine presented to the emergency department with a 4-day history of fever, cough, and difficulty breathing at rest. One day before the onset of symptoms, a pruritic rash had developed on his face, trunk, and…
Thu Sep 12, 2019 03:00
A 56-year-old man presented to the dermatology clinic with an ulcerated lesion on the palm of his right hand. Approximately 40 years earlier, he had been treated with radiation therapy for palmar hyperhidrosis of both hands. The patient had received a total dose of 25.6 Gy of radiation to both…
Thu Sep 12, 2019 03:00
Diabetes mellitus (DM) is burgeoning as a global chronic health condition. Some studies suggest that tuberculosis (TB) can even cause diabetes in those not previously known to be diabetic, which as a corollary...
Wed Sep 11, 2019 03:00
Publication date: Available online 11 September 2019Source: Practical Radiation OncologyAuthor(s): Ritu Arya, Tomoko Ichikawa, Brian Callender, Olivia Schultz, Marina DePablo, Kira Novak, Shanyanyan Li, MDes, Apoorva Shenoy, Andrea Everman, Sarah Braunstein, Isabel Dec, Sonia Lala, Yachu Feng, Laura Biltz, Anne R. McCall, Daniel W. GoldenAbstractPurposeCurrent radiation oncology patient education materials are above national readability recommendations. A graphic narrative educational tool, the Communicating...
Thu Sep 12, 2019 19:27
This randomized clinical trial assesses the effect of a vibratory anesthetic device during dermatologic surgery on patients who catastrophize pain as well as those who do not catastrophize pain.
Thu Sep 12, 2019 03:00
I recently received a call from a friend and palliative care colleague whose mother had metastatic uterine cancer. She had developed jaundice and escalating pain and needed to be admitted to our hospital. A flurry of phone calls followed between members of our team: How would we provide palliative…
Thu Sep 12, 2019 03:00
In China, 120 million persons have chronic kidney disease, a prevalence that is projected to increase. Anemia is present in more than 90% of the 500,000 patients who undergo dialysis and is a complication that contributes to increased morbidity and mortality. Treatment for anemia is recommended by…
Thu Sep 12, 2019 03:00
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