Related ArticlesLong-term outcomes of gamma knife radiosurgery for cystic vestibular schwannomas. World Neurosurg. 2019 Sep 11;: Authors: Lim SH, Park CK, Park BJ, Lim YJ Abstract OBJECTIVE: Vestibular schwannomas (VS) can either be solid or contain variable amounts of cystic components. It is established that gamma knife radiosurgery (GKS) was an effective treatment modality for solid VS. However, in case of the cystic VS, Given the somewhat unpredictable...
Sun Sep 15, 2019 14:27
Related Articles"Anatomical aspects of the transnasal endoscopic access to the craniovertebral junction." World Neurosurg. 2019 Sep 11;: Authors: Nikolaevich SA, Nikolaevich NV, Valerievich CI, Nikolaevich AD, Alekseevich SM, Gennadievich CK, Yegorovich SM Abstract Interest in endoscopic transnasal access has increased with continued technological advances in endoscopic technology. OBJECTIVE: The goals of this study were to review the normal...
Sun Sep 15, 2019 14:27
Related ArticlesGlioma resection unmasks eloquent brain areas. World Neurosurg. 2019 Sep 11;: Authors: Pallud J, Roux A, Mellerio C PMID: 31520765 [PubMed - as supplied by publisher]
Sun Sep 15, 2019 14:27
Related ArticlesPolymorphous low-grade neuroepithelial tumor of the young: a case report with genomic findings. World Neurosurg. 2019 Sep 11;: Authors: Gupta VR, Giller C, Kolhe R, Forseen SE, Sharma S Abstract BACKGROUND: Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently recognized epileptogenic neuroepithelial tumor. Despite its distinctiveness, its polymorphous histology and the nature of its oligodendrocyte-like cells...
Sun Sep 15, 2019 14:27
Publication date: Available online 12 September 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Sterre A.S. Hamann, Simone K. van der Velden, Marianne G.R. de Maeseneer
Fri Sep 13, 2019 14:01
Publication date: Available online 13 September 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Sandra Hischke, Henrik C. Rieß, Maria K. Bublitz, Levente Kriston, Thea Schwaneberg, Martin Härter, Daniel Bertges, Eike S. Debus, Christian-Alexander BehrendtObjectivesThis systematic review aimed to identify evidence based quality indicators for invasive revascularisation of symptomatic peripheral arterial occlusive disease (PAOD).MethodsA systematic search of clinical practice...
Sat Sep 14, 2019 15:34
Publication date: Available online 14 September 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Xavier Chaufour, Jean Segal, Raphael Soler, Guillaume Daniel, Eugenio Rosset, Jean-Pierre Favre, Pierre-Edouard Magnan, Jean Baptiste Ricco, Association Universitaire de Recherche en Chirurgie (AURC)ObjectivesWith a focus on renal function, the goal of this multicentre study was to assess peri-operative complications and late mortality of open surgical repair (OSR) of juxtarenal...
Sun Sep 15, 2019 13:03
Publication date: Available online 14 September 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): David Bergqvist, Larsolof Hafström, Pelle GustafsonObjectivesPatient treatment within the Swedish medical service system can claim negligence injuries to the malpractice insurance review board and request financial compensation. The aim of this paper was to analyse the consequences of a negligence claim after arterial surgery between two periods with increasing use of endovascular...
Sun Sep 15, 2019 13:03
Sharing a poster presentation done in Medcon2019 by Harika B 1styear PG & DR.ANV Prasad, Associate Professor NRI Institute of Medical Sciences CT Findings: Severe ascites seen. Multiple small enhancing nodules seen in the parietal peritoneum, visceral peritoneum and omentum with predominant pelvic distribution. Heterogeneously enhancing lesion of 3x2.1x1.8cm seen in RIF. Appendix is not seen separately from the lesion. Final Impression of Peritoneal carcinomatosis (pseudomyxoma peritoni) - likely...
Sun Sep 15, 2019 13:04
Related ArticlesSniffing behaviour-related changes in cardiac and cortical activity in rats. J Physiol. 2019 Sep 12;: Authors: Kuga N, Nakayama R, Shikano Y, Nishimura Y, Okonogi T, Ikegaya Y, Sasaki T Abstract KEY POINTS: High-frequency (HF) sniffing represents active odour sampling and an increased animal's motivation We examined how HF sniffing affects the physiological activity of the brain-body system During HF sniffing, heart rates and the ratio...
Fri Sep 13, 2019 15:51
Related ArticlesMotor unit behaviour of the aging human diaphragm: mid-life crisis for the inspiratory pump? J Physiol. 2019 Sep 13;: Authors: O'Halloran KD PMID: 31519028 [PubMed - as supplied by publisher]
Sat Sep 14, 2019 14:21
Related ArticlesSkeletal muscle nitrate storage - the missing piece of the nitrate supplementation puzzle? J Physiol. 2019 Sep 13;: Authors: Wickham KA, Nyakayiru J, McCarthy DG, Cervone DT PMID: 31520400 [PubMed - as supplied by publisher]
Sun Sep 15, 2019 13:04
Related ArticlesSerotonin exerts a direct modulatory role on bladder afferent firing in mice. J Physiol. 2019 Sep 14;: Authors: Konthapakdee N, Grundy L, O'Donnell T, Garcia-Caraballo S, Brierley SM, Grundy D, Daly DM Abstract KEY POINTS: Functional disorders (i.e., interstitial cystitis/painful bladder syndrome and irritable bowel syndrome) are associated with hyperexcitability of afferent nerves innervating the urinary tract and the bowel respectively....
Sun Sep 15, 2019 15:06
Related ArticlesGamma Knife surgery for clival epidural-osseous dural arteriovenous fistulas. J Neurosurg. 2018 05;128(5):1364-1371 Authors: Lee CC, Chen CJ, Chen SC, Yang HC, Lin CJ, Wu CC, Chung WY, Guo WY, Hung-Chi Pan D, Shiau CY, Wu HM Abstract OBJECTIVE Clival epidural-osseous dural arteriovenous fistula (DAVF) is often associated with a large nidus, multiple arterial feeders, and complex venous drainage. In this study the authors report the outcomes...
Fri Sep 13, 2019 14:23
Related ArticlesEditorial: the middle cranial fossa approach. Curr Opin Otolaryngol Head Neck Surg. 2018 Oct;26(5):275 Authors: Samy RN PMID: 30102613 [PubMed - indexed for MEDLINE]
Fri Sep 13, 2019 14:23
Related ArticlesEndoscopic Versus Open Resection of Non-Squamous Cell Carcinoma Sinonasal Malignancies. Laryngoscope. 2019 Sep 12;: Authors: Povolotskiy R, Farber NI, Bavier RD, Cerasiello SY, Eloy JA, Hsueh WD Abstract OBJECTIVE: Non-squamous cell carcinoma (non-SCC) variants of sinonasal cancer are rare cancers which are optimally managed with complete surgical resection. This study aims to assess the impact of surgical approach on outcomes by comparison...
Fri Sep 13, 2019 14:23
Related ArticlesLong and Very-Long-Chain Ceramides Correlate with A More Aggressive Behavior in Skull Base Chordoma Patients. Int J Mol Sci. 2019 Sep 11;20(18): Authors: La Corte E, Dei Cas M, Raggi A, Patanè M, Broggi M, Schiavolin S, Calatozzolo C, Pollo B, Pipolo C, Bruzzone MG, Campisi G, Paroni R, Ghidoni R, Ferroli P Abstract BACKGROUND: Skull base chordomas are rare tumors arising from notochord. Sphingolipids analysis is a promising approach...
Sat Sep 14, 2019 13:48
Related ArticlesSurgical Management of Primary Skull Base Osteosarcomas: Impact of Margin Status and Patterns of Relapse. Neurosurgery. 2019 Sep 12;: Authors: Raza SM, Habib A, Wang WL, Gildey PW, Conley AP, Nader ME, Hanna EY, Su SY, DeMonte F Abstract BACKGROUND: Skull base osteosarcomas are aggressive neoplasms characterized by bony invasion and extracompartmental/extra-osseous soft tissue extension that pose obstacles to achieving complete resection....
Sat Sep 14, 2019 13:48
Related ArticlesAnterolateral thigh free flap in reconstruction of lateral skull base defects after oncological resection. Eur Arch Otorhinolaryngol. 2019 Sep 12;: Authors: Trojanowski P, Szymański M, Trojanowska A, Andrzejczak A, Szczepanek D, Klatka J Abstract PURPOSE: Evaluation of the utility of the free anterolateral thigh flap reconstruction of the defects resulting from radical temporal bone resection in the management of lateral skull base malignancies...
Sat Sep 14, 2019 13:48
Related ArticlesIsolated hypoglossal nerve palsy due to a jugular foramen schwannoma. Ideggyogy Sz. 2019 Jul 30;72(7-8):282-284 Authors: Öztop-Çakmak Ö, Vanli-Yavuz E, Aygün S, Bastan B, Egemen E, Solaroğlu I, Gursoy-Ozdemir Y Abstract Introduction - Although the involvement of the hypoglossal nerve together with other cranial nerves is common in several pathological conditions of the brain, particularly the brainstem, isolated hypoglossal nerve palsy...
Sat Sep 14, 2019 15:45
Related ArticlesBenign notochordal cell tumor of the clivus with chordoma component: report of 2 cases. J Neurosurg. 2019 Sep 13;:1-5 Authors: Peris-Celda M, Salgado-Lopez L, Inwards CY, Raghunathan A, Carr CM, Janus JR, Stokken JK, Van Gompel JJ Abstract Benign notochordal cell tumors (BNCTs) are considered to be benign intraosseous lesions of notochord origin; however, recent spine studies have suggested the possibility that some chordomas arise from...
Sat Sep 14, 2019 15:45
Related ArticlesAn Anatomical Feasibility Study for Revascularization of the Ophthalmic Artery. Part II: Intraorbital Segment. World Neurosurg. 2019 Sep 11;: Authors: Rubio RR, Vigo V, Gandhi S, Tabani H, Meybodi AT, Winkler EA, Abla AA, Lawton MT, Benet A Abstract INTRODUCTION: Distal ophthalmic artery (OpA) aneurysms are a rare subset of vascular lesions with lack of optimal treatment. The management of these aneurysms may require complete occlusion...
Sun Sep 15, 2019 15:03
Related ArticlesEffects of an Evidence-Informed Healthy Eating Blog on Dietary Intakes and Food-Related Behaviors of Mothers of Preschool- and School-Aged Children: A Randomized Controlled Trial. J Acad Nutr Diet. 2019 Sep 10;: Authors: Dumas AA, Lemieux S, Lapointe A, Provencher V, Robitaille J, Desroches S Abstract BACKGROUND: Although social media such as blogs are still considered innovative communication technologies, some registered dietitians...
Sun Sep 15, 2019 13:07
Related ArticlesEfficacy of Ginger (Zingiber officinale) in Ameliorating Chemotherapy-Induced Nausea and Vomiting and Chemotherapy-Related Outcomes: A Systematic Review Update and Meta-Analysis. J Acad Nutr Diet. 2019 Sep 10;: Authors: Crichton M, Marshall S, Marx W, McCarthy AL, Isenring E Abstract BACKGROUND: Ginger has been proposed as an adjuvant treatment for chemotherapy-induced nausea and vomiting. OBJECTIVE: The aim of this systematic...
Sun Sep 15, 2019 13:07
Related ArticlesOsmotolerance of Dekkera bruxellensis and the role of two Stl glycerol-proton symporters. FEMS Microbiol Lett. 2018 03 01;365(5): Authors: Zemancíková J, Dušková M, Elicharová H, Papoušková K, Sychrová H Abstract Dekkera bruxellensis is important for lambic beer fermentation but is considered a spoilage yeast in wine fermentation. We compared two D. bruxellensis strains isolated from wine and found that they differ in some basic properties,...
Fri Sep 13, 2019 14:13
Related ArticlesDe novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy. Autophagy. 2019 Sep 13;:1-17 Authors: Andrejeva G, Gowan S, Lin G, Wong Te Fong AL, Shamsaei E, Parkes HG, Mui J, Raynaud FI, Asad Y, Vizcay-Barrena G, Nikitorowicz-Buniak J, Valenti M, Howell L, Fleck RA, Martin LA, Kirkin V, Leach MO, Chung YL Abstract Macroautophagy/autophagy can enable cancer cells to withstand...
Sat Sep 14, 2019 14:44
Related ArticlesPaneth cell dysfunction mediates alcoholic steatohepatitis through promoting bacterial translocation in mice: role of zinc deficiency. Hepatology. 2019 Sep 14;: Authors: Zhong W, Wei X, Hao L, Lin TD, Yue R, Sun X, Guo W, Dong H, Li T, Ahmadi AR, Sun Z, Zhang Q, Zhao J, Zhou Z Abstract Microbial dysbiosis is associated with alcoholic hepatitis (AH) with the mechanisms yet to be elucidated. The present study aimed to determine the effects...
Sun Sep 15, 2019 15:06
Related ArticlesDifferential Roles of Rad18 and Chk2 in Genome Maintenance and Skin Carcinogenesis Following UV Exposure. J Invest Dermatol. 2018 12;138(12):2550-2557 Authors: Tanoue Y, Toyoda T, Sun J, Mustofa MK, Tateishi C, Endo S, Motoyama N, Araki K, Wu D, Okuno Y, Tsukamoto T, Takeya M, Ihn H, Vaziri C, Tateishi S Abstract Defects in DNA polymerase Eta (Polη) cause the sunlight-sensitivity and skin cancer-propensity disorder xeroderma pigmentosum...
Fri Sep 13, 2019 13:43
Related ArticlesGADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells. Genes Dev. 2019 07 01;33(13-14):782-798 Authors: Schüle KM, Leichsenring M, Andreani T, Vastolo V, Mallick M, Musheev MU, Karaulanov E, Niehrs C Abstract Mouse embryonic stem cell (ESC) cultures contain a rare cell population of "2C-like" cells resembling two-cell embryos, the key stage of zygotic genome activation (ZGA). Little is known about positive...
Fri Sep 13, 2019 13:43
Related ArticlesA Novel Tanshinone Analog Exerts Anti-Cancer Effects in Prostate Cancer by Inducing Cell Apoptosis, Arresting Cell Cycle at G2 Phase and Blocking Metastatic Ability. Int J Mol Sci. 2019 Sep 10;20(18): Authors: Wang M, Zeng X, Li S, Sun Z, Yu J, Chen C, Shen X, Pan W, Luo H Abstract Prostate cancer (PCa), an epithelial malignant tumor, is the second common cause of cancer death among males in western countries. Thus, the development of...
Fri Sep 13, 2019 13:43
Related ArticlesMechanisms of Stress-Induced Spermatogenesis Impairment in Male Rats Following Unpredictable Chronic Mild Stress (uCMS). Int J Mol Sci. 2019 Sep 10;20(18): Authors: Zou P, Wang X, Yang W, Liu C, Chen Q, Yang H, Zhou N, Zeng Y, Chen H, Zhang G, Liu J, Cao J, Ao L, Sun L Abstract The negative association between psychological stress and male fertility has been known for many years. This study was aimed at (i) identifying spermatogenesis...
Fri Sep 13, 2019 13:43
Related ArticlesSecond Generation mTOR Inhibitors as a Double-Edged Sword in Malignant Glioma Treatment. Int J Mol Sci. 2019 Sep 10;20(18): Authors: Heinzen D, Divé I, Lorenz NI, Luger AL, Steinbach JP, Ronellenfitsch MW Abstract Glioblastomas (GBs) frequently display activation of the epidermal growth factor receptor (EGFR) and mammalian target of rapamycin (mTOR). mTOR exists as part of two multiprotein complexes, mTOR complex 1 (mTORC1) and 2 (mTORC2)....
Fri Sep 13, 2019 13:43
Related ArticlesPOT1 and Damage Response Malfunction Trigger Acquisition of Somatic Activating Mutations in the VEGF Pathway in Cardiac Angiosarcomas. J Am Heart Assoc. 2019 Sep 17;8(18):e012875 Authors: Calvete O, Garcia-Pavia P, Domínguez F, Mosteiro L, Pérez-Cabornero L, Cantalapiedra D, Zorio E, Ramón Y Cajal T, Crespo-Leiro MG, Teulé Á, Lázaro C, Morente MM, Urioste M, Benitez J Abstract Background Mutations in the POT1 gene explain abnormally long...
Fri Sep 13, 2019 13:43
Related ArticlesCheckpoint signaling and error correction require regulation of the MPS1 T-loop by PP2A-B56. J Cell Biol. 2019 Sep 11;: Authors: Hayward D, Bancroft J, Mangat D, Alfonso-Pérez T, Dugdale S, McCarthy J, Barr FA, Gruneberg U Abstract During mitosis, the formation of microtubule-kinetochore attachments is monitored by the serine/threonine kinase monopolar spindle 1 (MPS1). MPS1 is recruited to unattached kinetochores where it phosphorylates...
Fri Sep 13, 2019 13:43
Related Articles1,7-Bis(4-hydroxyphenyl)-4-hepten-3-one from Betula platyphylla induces apoptosis by suppressing autophagy flux and activating the p38 pathway in lung cancer cells. Phytother Res. 2019 Sep 11;: Authors: Jung HJ, Song KS, Son YK, Seong JK, Kim SY, Oh SH Abstract Betula platyphylla (BP) is frequently administered in the treatment of various human diseases, including cancers. This study was undertaken to investigate the pharmacological function...
Fri Sep 13, 2019 13:43
Related ArticlesHigh expression of PRKDC promotes breast cancer cell growth via p38 MAPK signaling and is associated with poor survival. Mol Genet Genomic Med. 2019 Sep 12;:e908 Authors: Zhang Y, Yang WK, Wen GM, Tang H, Wu CA, Wu YX, Jing ZL, Tang MS, Liu GL, Li DZ, Li YH, Deng YJ Abstract BACKGROUND: DNA-Dependent Protein Kinase Catalytic Subunit (PRKDC), a key component of the DNA damage repair pathway, is associated with chemotherapy resistance and...
Fri Sep 13, 2019 14:43
Related ArticlesMitotic spindle defects and DNA damage induced by dimethoxycurcumin lead to an intrinsic apoptosis pathway in HepG2/C3A cells. Toxicol In Vitro. 2019 Sep 09;:104643 Authors: Zanetti TA, Biazi BI, Coatti GC, Baranoski A, Marques LA, Corveloni AC, Mantovani MS Abstract Dimethoxycurcumin (DiMC), a synthetic analog of curcumin, was shown to have antiproliferative activity in human tumor cell lines. Therefore, we investigated its cytotoxic,...
Fri Sep 13, 2019 14:43
Related ArticlesDefining the Most Appropriate Primary End Point in Phase 2 Trials of Immune Checkpoint Inhibitors for Advanced Solid Cancers: A Systematic Review and Meta-analysis. JAMA Oncol. 2018 Apr 01;4(4):522-528 Authors: Ritchie G, Gasper H, Man J, Lord S, Marschner I, Friedlander M, Lee CK Abstract Importance: Checkpoint inhibitors have a unique mechanism of action that differs from chemotherapy or targeted therapies. The validity of objective...
Sat Sep 14, 2019 13:58
Related ArticlesPhospholipase C delta 4 (PLCδ4) is a nuclear protein involved in cell proliferation and senescence in mesenchymal stromal stem cells. Cell Signal. 2018 Sep;49:59-67 Authors: Kunrath-Lima M, de Miranda MC, Ferreira ADF, Faraco CCF, de Melo MIA, Goes AM, Rodrigues MA, Faria JAQA, Gomes DA Abstract Ca2+ is an important second messenger, and it is involved in many cellular processes such as cell death and proliferation. The rise in intracellular...
Sat Sep 14, 2019 13:58
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