Related ArticlesThree-dimensional analysis of lip changes in response to simulated maxillary incisor advancement. Angle Orthod. 2019 Aug 09;: Authors: Au J, Mei L, Bennani F, Kang A, Farella M Abstract OBJECTIVE: To assess the immediate response of lips in three dimensions (3D) resulting from simulated maxillary incisor advancement. MATERIALS AND METHODS: Incremental maxillary incisor advancement was simulated by placing wax of increasing thickness...
Related ArticlesA comparative assessment of orthodontic treatment outcomes of mild skeletal Class III malocclusion between facemask and facemask in combination with a miniscrew for anchorage in growing patients: A single-center, prospective randomized controlled trial. Angle Orthod. 2019 Aug 09;: Authors: Seiryu M, Ida H, Mayama A, Sasaki S, Sasaki S, Deguchi T, Takano-Yamamoto T Abstract OBJECTIVES: To investigate the hypothesis that there is difference...
Related ArticlesThree-dimensional evaluation of mandibular volume in patients with cleft lip and palate during the deciduous dentition period. Angle Orthod. 2019 Aug 09;: Authors: Shrestha A, Takahashi M, Yamaguchi T, Adel M, Furuhata M, Hikita Y, Yoshida H, Nakawaki T, Maki K Abstract OBJECTIVES: To examine the relationship between mandibular volume and craniofacial morphology in patients with cleft lip and palate using cone beam computed tomography...
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Abstract Background Osteoblast adhesion is a crucial step in osseointegration of dental implants and can be influenced by modification of implant surface or the addition of bioactive agents. Bisphosphonates affect bone turnover, attenuating bone healing in implants patients. PRP and PRF are sources of growth factors involved in osteoblast adhesion, improving subsequent bone healing. The aim of the study was to investigate the impacts of PRP and PRF on adhesion of bisphosphonate‐pretreated osteoblasts...
Abstract Background Oral submucous fibrosis (OSF) is a potentially malignant lesion characterized by epithelial–mesenchymal transition (EMT). Bone morphogenetic protein 4 (BMP4) promotes EMT in fibrotic diseases, but the underlying mechanisms and its potential role in OSF are unclear. This study investigates whether BMP4 plays a role in the pathogenesis of OSF and explores the underlying mechanisms. Methods The expression of BMP4 and the EMT proteins E‐cadherin and vimentin was investigated...
Abstract Background Increasing evidence suggests that dysregulated long non‐coding RNAs (lncRNAs) are involved in tumorigenesis and progression. RP11‐284F21.9, one of the temporally expressed S‐phase lncRNAs in cancer cells, was recently identified by nascent RNA capture sequencing. Methods Cal‐27, Tca8113, SCC‐9, HB56, and oral squamous cell carcinoma (OSCC) tissues were used in the experiment. RNA extraction, qRT‐PCR, plasmid construction, cell proliferation, EdU labeling, Transwell migration,...
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Abstract Aim The aim of the present study was to evaluate the prevalence of HPV infection in oral leukoplakia, specifying the HPV genotypes eventually involved. We also compared the micro-biopsy and brushing HPV detecting efficacy. Materials and methods Consecutive patients with a presumptive diagnosis of oral leukoplakia were enrolled. Demographical, behavioral...
Abstract Objective To propose a modified protocol of mandibular osteoradionecrosis induction in rats with external beam radiation therapy. Material and methods A total of 45 male Wistar rats were used in this study. Firstly, 25 rats were divided into 5 groups (n = 5) according to the radiation dose protocol: without irradiation and irradiated with 15 Gy,...
Abstract Objective Compositional modifications may alter the biological and physicochemical characteristics of calcium silicate-based sealers (CSBS) and, ultimately, their bioactivity. The main objective of this study was to evaluate the biological properties of three CSBS: EndoSequence BC Sealer, Ceraseal, and Endoseal mineral trioxide aggregate. Materials and methods ...
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Publication date: Available online 9 August 2019Source: The Journal of Prosthetic DentistryAuthor(s): David R. Cagna, Terence E. Donovan, James R. McKee, Frederick Eichmiller, James E. Metz, Jean-Pierre Albouy, Riccardo Marzola, Kevin R. Murphy, Matthias TroeltzschAbstractThis comprehensive review of the 2018 dental literature is provided to inform busy dentists about progress in the profession. Developed by the Committee on Scientific Investigation of the American Academy of Restorative Dentistry,...
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Subhajit Routh, Mithun Pai, Gururaghavendran Rajesh, Ramya Shenoy, Swapna SaritJournal of Orofacial Sciences 2019 11(1):49-54 Introduction: Probiotics are microorganisms that are administered in live forms and can improve health and well being of human beings. Literature about their antimicrobial activity against oral pathogens is limited. The present study was conceptualized to ascertain the antimicrobial capabilities of common probiotics against microorganisms involved in dental caries and periodontal...
Yu-Cheng Chen, Derek Jin-Ki Hong, Chia-Wei Wu, Muralidhar MupparapuJournal of Orofacial Sciences 2019 11(1):3-10 Introduction: This review sought to present fundamental principles of deep convolutional neural networks (DCNNs) and provides an overview of its applications in medicine and dentistry. Materials and Methods: Scientific databases including PubMed, Science Direct, Web of Science, JSTOR, and Google Scholar were used to search for relevant literature on DCNN and its applications in the medical...
Mel MupparapuJournal of Orofacial Sciences 2019 11(1):1-2
Deepa Anumala, Modem Haritha, Sistla Sailaja, Egatela Prasuna, Gujjula Sravanthi, Nagireddy Ravindra ReddyJournal of Orofacial Sciences 2019 11(1):11-15 Introduction: Over the past 30 years, flap designs for implant surgery have been modified and atraumatic technique was introduced. It has several potential advantages, including reduction of complications at the patient level. The aim of the present study to compare the soft tissue profile and heights of crestal bone levels around the single-stage...
Maya Ramesh, Vinod Thomas, Balakrishnan Sekar, Jissy GeorgeJournal of Orofacial Sciences 2019 11(1):59-64 Introduction: Odontogenic keratocysts, dentigerous cysts, and ameloblastoma are the most common forms of cystic pathology that affect the jaw bones. The purpose of this study was to assess the immunohistochemical expression of laminin 1 in these lesions and to study the probable role of laminin 1 in their biologic behavior. Materials and Methods: Serial sections of 4 µm were obtained from the...
Maria Paço, Daniela Simões, Paula Chaves, Vera Almeida, Jose Carlos Rocha, Lilliana Moreira, Jose Alberto Duarte, Teresa PinhoJournal of Orofacial Sciences 2019 11(1):16-26 Introduction: The purpose of this article was to develop and validate a scale to assess common knowledge about temporomandibular disorders (TMDs) in the general population, evaluate the status of TMDs knowledge in the Portuguese population, quantify the severity and prevalence of TMDs-related symptoms in the general population,...
Anusa Arunachalam Mohandoss, Rooban Thavarajah, Elizabeth Joshua, Umadevi Krishnamohan Rao, Kannan RanganathanJournal of Orofacial Sciences 2019 11(1):37-48 Intoduction: Suicide is relatively more common among cancer patients as compared to general population. There are several identified candidate genes for suicide (CGS). There is a dearth of research examining the association of differential expression (DE) of CGS among the treatment-naïve head and neck squamous cell carcinoma (HNSCC) patients....
Nikita Rungta, Ramya Shenoy KudpiJournal of Orofacial Sciences 2019 11(1):27-31 Introduction: Eating disorders can cause serious changes in eating habits that can lead to major, even life-threatening, health problems. This may cause devastating effects on teeth. Materials and Methods: The present study was conducted to assess eating disorders among 15 to 17-year-old female cohorts. The SCOFF [sick, control, one stone (1 stone is 6.3 kg), fat, and food] Questionnaire was distributed among the consented...
Sankar Leena Sankari, Krishnan MahalakshmiJournal of Orofacial Sciences 2019 11(1):55-58 Introduction: Etiology of oral squamous cell carcinoma is multifaceted. The established risk factors include tobacco, alcohol, and immunodeficiency states with infections gaining an importance. Candida species has been implicated in oral squamous cell carcinoma (OSCC). The present study aims at determining the prevalence of Candida species in the saliva of patients with OSCC and healthy cohorts. Materials and...
Marcelo Coelho Goiato, Adhara Smith Nobrega, Estefania Marrega Malavazi, Aline Satie Takamiya, Sandra Helena Penha de OliveiraJournal of Orofacial Sciences 2019 11(1):32-36 Introduction: Although physical and mechanical properties are extremely important for the effectiveness of prosthetic treatment, materials used for facial rehabilitation should be biocompatible, as the maxillofacial prosthesis is in close contact with the patient’s skin. The objective of this study was to evaluate the influence...
Steven Richard Singer, Mel MupparapuJournal of Orofacial Sciences 2019 11(1):65-70 Carotid artery calcification is frequently noted in panoramic dental radiographs but more evident on cone beam computed tomography (CBCT) examinations. Vertebral artery calcification and ectasia, although rare, can place the patient for equal risk for a cerebrovascular accident (stroke). The aim of this article is to radiographically identify calcified atheromatous plaque, as well as, atresia related to vertebral...
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Abstract Objectives To evaluate the patient population over a three‐year period and to compare it to observations of the population at the same clinic over a period of 15 years. Material and Methods Records of patients receiving dental implants in the Department of Oral Surgery and Stomatology, University of Bern, between January 2014 and December 2016 were analyzed and then compared to data from patients treated between 2002 and 2004 and between 2008 and 2010. Patients were analyzed for...
Abstract Objectives As biomaterial‐induced modulation of mediators of the immune response may be a potential therapeutic approach to enhance wound healing events, the aim of this study was to delineate the effects of titanium surface modification on macrophage phenotype and function. Material and methods Rodent bone marrow derived macrophages were polarised into M1 and M2 phenotypes and cultured on micro‐rough (SLA) and hydrophilic modified SLA (modSLA) titanium discs. Macrophage phenotype...
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Publication date: Available online 10 August 2019Source: Archives of Oral BiologyAuthor(s): Işıl Kaya Büyükbayram, Rüstem Kemal Sübay, Gizem Çolakoğlu, Mehmet Ali Elçin, Melike Ordulu SübayAbstractObjectiveTo conduct an in vivo evaluation of prevalence of root canal configurations, lengths of C-shaped canals, prevalence and depths of radicular grooves (RGs), in mandibular first and second premolars in a Turkish subpopulation using cone beam computed tomography (CBCT).Materials and methodsCBCT images...
Publication date: Available online 10 August 2019Source: Archives of Oral BiologyAuthor(s): Jingya Hou, Yanqing Liu, Xiaomeng Xue, Yun Wu, Rong Li, Tong Xu, Yaping Pan, Dongmei ZhangAbstractObjectiveThe aim of this study was to explore the role of macrophage migration inhibitory factor (MIF) and intercellular adhesion molecule (ICAM)-1 in rats with periodontitis and atherosclerosis.MethodsTwenty-four male Sprague-Dawley rats were randomly divided into 4 groups: control group (C), periodontitis group...
Publication date: Available online 9 August 2019Source: Archives of Oral BiologyAuthor(s): Alana Cristina Machado, Sávio José Cardoso Bezerra, Samira Helena João-Souza, Tainá Mautone Caetano, Luciano Citadini Russo, Thiago Saads Carvalho, Taís ScaramucciAbstractObjectives1. To evaluate the use of fluoridated mouthrinses before or after toothbrushing on erosive tooth wear. 2. To compare the anti-erosive effect of the combination toothpaste and mouthrinse containing fluoride, with or without stannous...
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Publication date: Available online 8 August 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): T. Cooper, B. Schmutz, E. Hsu, A. LynhamAbstractThe aim of this study was to examine the accuracy of three dimensionally (3D) printed models of the bony orbit derived from magnetic resonance imaging (MRI) for the purpose of preoperative plate bending in the setting of orbital blowout fracture. Retrospective computed tomography (CT) and MRI data from patients with suspected orbital...
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Publication date: Available online 9 August 2019Source: Dental MaterialsAuthor(s): Enrico Coser Bridi, Ariene Arcas Leme-Kraus, Roberta Tarkany Basting, Ana Karina Bedran-RussoAbstractObjectiveThis study investigated the effects of dentin pretreatment with 2.5% titanium tetrafluoride (TiF4) on nanomechanical properties, and the in situ gelatinolytic activity of the dentin–resin interface, for up to 6 months.MethodsTwenty-four human teeth were prepared by exposing occlusal flat dentin surfaces, and...
Publication date: Available online 9 August 2019Source: Dental MaterialsAuthor(s): Gabriela de Souza Balbinot, Vicente Castelo Branco Leitune, Deise Ponzoni, Fabricio Mezzomo CollaresAbstractObjectiveThe aim of this study is to investigate bone healing ability of niobium-containing bioactive glasses in rat femur model with quantitative and qualitative measurements through x-ray computed microtomography.MethodsNiobium-containing bioactive powders and scaffolds were produced by sol–gel route (BAGNb)....
Publication date: Available online 8 August 2019Source: Dental MaterialsAuthor(s): Saoirse O’Toole, Cecilie Osnes, David Bartlett, Andrew KeelingAbstractObjectivesThe use of surface matching software with intraoral scanners is developing rapidly which increases the need for accessible, accurate and validated measurement software. This investigation compared the current gold-standard Geomagic Control software to a purpose-built software “WearCompare”.MethodsArtificially created occlusal defects of...
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The standard treatment of oral submucous fibrosis is fibrotomy together with a coronoidotomy or coronoidectomy, or both, and the extraction of all third molars. To achieve predictable mouth opening without recurrence, reconstruction with a buccal fat pad or nasolabial flap are most commonly used, but both techniques have limitations.
The quality of the bone plays an important part in marginal bone loss (MBL) around dental implants. The aim of this study was to compare MBL around implants the sockets of which had been preserved with the bone around healed sites in the mandible after extraction of first molars. It was a prospective, cohort study in which subjects were divided into three groups (n=30 in each): dental implants were placed six months after preservation of the socket in the first group, eight weeks after tooth extraction...
Fabry disease and Pompe disease are rare lysosomal storage disorders that belong to a heterogeneous group of more than 200 distinct inborn metabolic diseases. Mutations followed by loss of function of enzymes or transporters that are localised in the acidic environment of the lysosome may result in degradation of many substrates, such as glycosaminoglycans, glycosphingolipids, glycogen, cholesterol, oligosaccharides, glycoproteins, and peptides, or the excretion of the products degraded by the lysosome.
Fractures of the mandibular condyle lead to displacement of the condyle and loss of the height of the ramus. A retromandibular approach is the most commonly used for open reduction and internal fixation (ORIF) of such fractures. We aimed to compare the complications associated with a retromandibular transparotid approach with a retromandibular transmasseteric anterior parotid (TMAP) approach for their management. Thirty patients were randomly selected into two groups (15 in each): Group A comprised...
Carcinoma ex pleomorphic adenoma is a rare type of cancer of the salivary gland that involves the malignant transformation of a primary or recurrent pleomorphic adenoma, which often metastasises to the lungs or bones, or both. To the best of our knowledge, however, nobody has reported a distant metastasis of this lesion to the brain without such previous metastasis. We report a case in a 64-year-old man.
Deep space infections in the oral and maxillofacial region occur when an infectious process spreads through the potential spaces bounded by the deep cervical fascia in the head and neck. These infections are usually odontogenic in origin, but can be the result of trauma, immunosuppression, or disease.1 Incision and drainage are still the treatments of choice, with management of the source if possible, and drains are often left in place afterwards.
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Abstract Objective Epithelial‐mesenchymal transition (EMT) is important in the tooth development and tumor invasion. We investigated the effect of interleukin‐8 (IL‐8) on the EMT process in primary‐cultured ameblastoma tumor cells (AM‐P) and ameloblastoma immortalized tumor cells (AM‐L) and its underlying mechanism. Methods IL‐8 levels in ameloblastomas were detected by immunofluorescence staining and ELISA. AM‐P cells and AM‐L cells were stimulated with IL‐8, and EMT transcription factors,...
Abstract Objective There are challenges in the treatment of chronic inflammatory diseases of oral mucosa. Both paeoniflorin (PF) and baicalin (BAI) exert anti‐inflammatory effects, but the mechanism underlying their combined effects is still unclear. Here, we explored the anti‐inflammatory function of the PF‐BAI combination in the oral inflammatory response. Materials and Methods The CCK‐8 assay was used to determine the proliferative capacity of HOKs with PF and BAI. Enzyme‐linked immunosorbent...
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