ObjectiveTo investigate the clinical characteristics of patients with early-onset hyperuricaemia (HUC). MethodsA retrospective study using data from the Second Affiliated Hospital of Soochow University was conducted. 623 patients with HUC were divided into early-onset group and late-onset group. Another 201 healthy subjects ≤40 years old were regarded as control group. The data of physical measurements and biochemistry test were collected. Clinical data of early-onset group were compared with late-onset...
38m
ObjectivesTo determine the relative extent that autism and intellectual disabilities are independently associated with poor mental and general health, in children and adults. DesignCross-sectional study. For Scotland’s population, logistic regressions investigated odds of intellectual disabilities and autism predicting mental health conditions, and poor general health, adjusted for age and gender. Participants1 548 819 children/youth aged 0-24 years, and 3 746 584 adults aged more than 25 years,...
38m
ObjectivesTo assess the association between receiving the certified care workers’ home care service, which is provided by non-medical professionals prior to a patients’ death and the probability of a home death. DesignObservational research using the full-time translated number of certified care workers providing home care service per member of the population aged 65 or above, during the year prior to patient’s death per municipality as an instrumental variable. SettingThe certified care workers’...
38m
ObjectivesThe influence of obesity on the outcomes of curative liver resection for malignancies remains controversial. We aimed to compare the in-hospital outcomes of liver resection for malignancy between obese and non-obese patients. DesignThis was a population-based, retrospective, observational study using data from the Nationwide Inpatient Sample (NIS), the largest all-payer US inpatient care database. SettingHospitalisations of adults ≥18 years old with diagnoses of primary hepatobiliary...
38m
Chronic back pain is on the rise – in part because the way we treat it often does more harm than good. It's time to think differently about our aches
39m
The lingering effects of the Deepwater Horizon oil spill have been extreme for deep sea creatures, with biodiversity still down years after the disaster
6h
Your skin is terrible at judging how fast different textured materials are moving, highlighting a strange quirk in how the brain encodes touch
9h
Last year, astronomers announced they’d found 12 new moons orbiting Jupiter, and now five of them have been named after daughters and granddaughters of Zeus
13h
People affected by multiple sclerosis hold the key to understanding the condition, says Catherine Lubetzki, and she hopes her work could one day stop MS in its tracks
18h
A device consisting of a smartphone and an attachable microscope can detect minuscule amounts of norovirus, which may help identify its spread earlier
20h
Abstract Composting process of residual organic material generates considerable amounts of liquid leachate which contains high organic load. This waste stream can be considered as potential nutrient source to support microbial growth. In the present work, the utilization of compost leachate as fermentation substrate for Bacillus species production was studied. The physicochemical properties of the leachate and two co-substrates (residual yeast and whey permeate) were determined....
40m
Abstract Effect of arsenate [As(V)] on biomass, photosynthetic rate, stomatal conductance, transpiration, oxidative stress, accumulation of As, Fe, Zn, Cu and Mn and expression of NRAMP genes was investigated in As(V) tolerant and sensitive genotypes of bioenergy crop Ricinus communis. As(V) treatments (100 and 200 μM) led to significant reduction in root and leaf biomass, photosynthetic rate, stomatal conductance and transpiration in GCH 2 and GCH 4 genotypes but no significant...
6h
Abstract Alternative energy policies targeting the adoption of hydrogen fuel cell vehicles (HFCVs) could have significant positive impacts on Malaysia’s ability to meet both its carbon reduction goal and its energy security needs. The transport sector generally contributes heavily to carbon emissions, and is also difficult to decarbonize because of the costs associated with many greener options. This study explores the possibility of decarbonizing the Malaysian transport sector...
6h
Abstract In this research, waste tyre rubber was used for activated carbon production with a novel route by modified physo-chemical approach. Potassium hydroxide and carbon dioxide were selected as chemical and physical activating agents, respectively and the process was carried out without carbonization under inert atmospheric conditions. The experiments were designed by applying the central composite design (CCD) as one of the subsets of response surface methodology (RSM). The...
12h
Abstract Semiconductors are promising photocatalysts for the use of sunlight in energy conversion and environmental remediation. To this end, various synthetic pathways have been proposed to increase their photocatalytic efficiency, catalytic stability, recycle, and reuse. In this work, mixed phase CdS nanoparticles were loaded on the surface of activated biomass carbons to prepare composite photocatalysts via hydrothermal syntheses, which were further applied to photocatalytic...
12h
Abstract Diquat dibromide (DB) is the active ingredient in several herbicide products used around the world for industrial and recreational control of terrestrial and aquatic pest plants. This study aimed to assess the adverse effects of the commercial formulation of the aquatic herbicide, Reward®, on the Pacific Northwest amphibian species, the northwestern salamander (Ambystoma gracile). Larvae were exposed to the Reward® herbicide in a 96-h acute bioassay (0.37–151.7 mg/L DB)...
12h
Abstract Worldwide, the requirement of electrical energy has increased with an increase in population. Thus, there is a need to develop an alternative source of sustainable energy, such as microbial fuel cell (MFC). MFC is a better option of energy generation and can provide a renewable resource which utilizes wastewater into power by the help of microorganisms. MFC is one of the advanced methods for treating wastewater and simultaneously producing current and voltage. Dual-chambered...
12h
Abstract The present study was conducted to examine the nephrotoxic effects of heavy metals including lead (Pb), manganese (Mn), arsenic (As), and cadmium (Cd) in diabetic and non-diabetic Wistar rats. Animals were exposed to heavy metals for 30 days, Pb was injected as lead acetate (C4H6O4Pb), Mn was injected as manganese chloride (MnCl2), Cd was injected as cadmium chloride (CdCl2), and As was administered orally to rats in the form of sodium arsenite (AsO2Na). Results showed...
17h
Abstract This work relates data from field sampling of Eisenia lucens and from laboratory-based culture. Field sampling used soil sorting and vermifuge extraction and took place in beech-dominated forests of southwest Poland. Initial work derived population estimates from four sub-communities of the forest looking for seasonal dynamics and later work employed targeted sampling in summer within rotting wood to obtain live specimens for laboratory culture. A preliminary examination...
17h
Abstract One of the most critical challenges is bird dropping deposition (soiling) on a glass surface of the photovoltaic (PV) module in an open environment of Western Rajasthan. This paper has been now exclusively emphasized to focus on effects of the bird dropping phenomenon on the performance of PV systems. The presented study includes the impact of the seasonal bird dropping effect on the reduction in energy yield with various tilt angle configurations. Considering this, the...
17h
Abstract With a length exceeding 210,000 km in Europe, railways are common linear features dissecting landscapes. However, the impact of railway networks on biodiversity is equivocal. In this study, we investigated the effect of railway embankments on bird diversity components in an agricultural landscape in southern Poland. Forty transects including 20 along railways and 20 as controls in open fields were established. Birds were counted twice in 2009, and environmental characteristics...
17h
Abstract Objective To describe the impact of a nurse-led telephone self-management support (SMS) service for people with asthma and COPD in Ireland. Methods A cross-sectional survey of all (442) SMS users, July 2016 to May 2017, described user demographics, self-reported experience, process and outcome. Population utilisation was estimated and compared across...
44m
The flow field distribution in an interelectrode gap is one of the important factors that affect the machining accuracy and surface quality in the electrochemical machining (ECM) process for aircraft blades. In the ECM process, some process parameters, e.g., machining clearance, processing voltage, and solution concentration, may result in electrolyte fluid field to be complex and unstable, which makes it very difficult to predict and control the machining accuracy of ECM. Therefore, 30 sets of experiments...
48m
Global pollution has caused a real interest on the use of biodegradable materials to the sustainable development. PLA and PHB are interesting materials due to their properties and their biodegradability, and their blends in different ratios are proposed in this study; also, Ag and Cu nanoparticles were incorporated to observe possible enhances and advantages on it. Blends were characterized through FTIR, TGA, tensile, and DMA tests. Theoretically, results obtained were coherent; FTIR spectra showed...
1h
Background. Diabetes is a progressive metabolic disease characterized by hyperglycemia. Functional impairment of islet β cells can occur to varying degrees. This impairment can initially be compensated for by proliferation and metabolic changes of β cells. Cell division control protein 42 (Cdc42) and the microRNA (miRNA) miR-29 have important roles in β-cell proliferation and glucose-stimulated insulin secretion (GSIS), which we further explored using the mouse insulinoma cell line MIN6. Methods....
1h
Proliferation and differentiation of adult Leydig cells are mainly completed in puberty. In many studies, apart from normal postnatal development process, it is widely indicated that, through administrating EDS, Leydig cell population is eliminated and regenerated. It is believed that osteocalcin released from osteoblasts, which is responsible for modulating bone metabolism, induces testosterone production in Leydig cells, independent of the HPG axis. In addition, INSL3 produced by Leydig cells,...
1h
C. elegans is a preferential model for testing environmental toxicity of compounds including nanomaterials. The impact of multigeneration exposure of gold nanoparticles (AuNPs) on the lifespan and fertility of C. elegans is not known and therefore is investigated in this study. We used pomegranate (Punica granatum) peel extracts as a reducing agent to synthesize gold nanoparticles (PPE-AuNPs) from chloroauric acid. Nematodes were grown till adult stage and then exposed to 25, 50, and 100 μg/ml of...
1h
Percutaneous vertebroplasty is often used to acquire the stability of the spine and relieve the pain caused by osteoporotic vertebral compressive fracture (OVCF). 125I seeds have been used for application of local therapy for tumors. A combined treatment was reported in previous literatures. Thus, this case report is aimed at reporting a patient with an occurrence of delayed radioactive myelopathy, who accepted percutaneous vertebroplasty combined with interstitial implantation of 125I seeds for...
1h
A miniaturized periodic microstrip leaky wave antenna (MLWA) with shorting pins is proposed in this paper. The suggested antenna consists of a number of stubs that are periodically placed on the side of the transmission line, with the outside edges of the stubs being all integrated with shorting pins. In comparison with the whole-width stubs MLWA, the proposed antenna has an advantage of effective reduction in antenna size for the similar beam-scanning capability. A series of simple and effective...
2h
In this study, we analyzed the meteorological processes associated with 2018 tropical cyclone No. 14, “Yagi.” TC Yagi continued moving northeastward after losing its numerical designation from the National Meteorological Center of the China Meteorological Administration (CMA) because of weakening and then restrengthened when it moved over the Bohai Sea, inducing an ocean gale on 14-15 August 2018. The results of our investigation revealed that the continued northeastward movement of Yagi on 14 August...
3h
Different molecular weight polysaccharides of Dendrobium officinale (DOPs) have gradually attracted attention because of their broad biological activities. They, however, remain poorly defined whether their antitumor activity is associated with molecular weight. In this study, the physicochemical, antioxidant, and antitumor properties of DOPs, including the crude polysaccharide (DOP) and its six degradation fractions (DOP1–DOP6) extracted from Dendrobium officinale, were determined. Consequently,...
4h
The Ahlfors map is a conformal mapping function that maps a multiply connected region onto a unit disk. It can be written in terms of the Szegö kernel and the Garabedian kernel. In general, a zero of the Ahlfors map can be freely prescribed in a multiply connected region. The remaining zeros are the zeros of the Szegö kernel. For an annulus region, it is known that the second zero of the Ahlfors map can be computed analytically based on the series representation of the Szegö kernel. This paper presents...
6h
Prior to the availability of digital cameras, the solar observational images are typically recorded on films, and the information such as date and time were stamped in the same frames on film. It is significant to extract the time stamp information on the film so that the researchers can efficiently use the image data. This paper introduces an intelligent method for extracting time stamp information, namely, the convolutional neural network (CNN), which is an algorithm in deep learning of multilayer...
6h
A fifty-eight-year-old, nonsmoker Indian male presented with recurrent left pleural effusion. He had history of dry cough, exertional breathlessness for the last two years. He denied any occupational exposure or second hand smoke exposure. His physical examination demonstrated decreased breath sounds on the left side of chest. Cardiac evaluation was unremarkable. Diagnostic pleural aspiration revealed straw coloured fluid, exudative, and nonmalignant in nature. CT-imaging of the chest demonstrated...
6h
A 54-year-old woman with acute-onset nausea and vomiting presented to outpatient clinic. She had headache for 3 weeks. She had difficulty during tandem gait and was falling to the right. Otherwise, her neurological examination was normal. She had normal hearing. VNG analysis revealed spontaneous nystagmus beating to the left with optical fixation. However, she had horizontal and slightly down-beating gaze-evoked nystagmus at primary gaze position. Temporal bone CT and MRI showed widespread encephalitis...
6h
To investigate the mechanism of hammer-soil interaction under the action of dynamic compaction (DC) on a coarse-grained soil foundation, based on the theory of projectile penetration, the continuous-discrete coupling method is used to simulate the hammer-soil interaction process with different hammer shapes and different particle radii. The physical phenomena and mechanical parameters presented by the hammers and soil particles are quantitatively analyzed. The results show that the penetrating ability...
6h
The dentate gyrus (DG) and its primary cell type, the granule cell (GC), are thought to be critical to many cognitive functions. A major neuronal subtype of the DG is the hilar mossy cell (MC). MCs have been considered to play an important role in cognition, but in vivo studies to understand the activity of MCs during cognitive tasks are challenging because the experiments usually involve trauma to the overlying hippocampus or DG, which kills hilar neurons. In addition, restraint typically occurs,...
15h
Introduction. Angiostrongylus costaricensis is a nematode from the superfamily Metastrongyloidea, whose etymology is “roundworm that lives in blood vessels”. This parasite can be found from the southern United States to northern Argentina and southern Brazil. In 1983, Morera and Ruiz published the first case of a testicular artery occlusion by A. costaricensis. Case Presentation. A five year old boy presented with eight days of pain, denying trauma backgrounds and followed with an increase of volume....
15h
Aneurysmal bone cysts (ABCs) are an uncommon osteolytic intraosseous bone lesions. ABCs commonly involve metaphysis of long bones and are rarely diagnosed in craniofacial bones. The World Health Organization (WHO) designates ABCs as benign, but locally destructive, rapidly growing masses. ABC can be clinically misdiagnosed as a malignant tumor. In this article, we present a case of a 12-year-old female patient who presented to a maxillofascial outpatient clinic complaining of huge jaw swelling over...
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