Τετάρτη 28 Αυγούστου 2019

Debates over NICE Guideline Update: What Are the Roles of Nuclear Cardiology in the Initial Evaluation of Stable Chest Pain?
Abstract Recent clinical trials have demonstrated the values of cardiac computed tomography (CT) in the initial evaluation of stable chest pain which led to drastic changes in the National Institute for Health and Care Excellence (NICE) guidelines in 2016. According to the updated NICE guidelines, cardiac CT should be performed as the initial cardiac testing in stable chest pain regardless of pre-test probability (PTP) of coronary artery disease (CAD). As a result, cardiac CT is...
Latest Results for Nuclear Medicine and Molecular Imaging
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Globally regional life cycle analysis of automotive lithium-ion nickel manganese cobalt batteries
Abstract Electric vehicles based on lithium-ion batteries (LIB) have seen rapid growth over the past decade as they are viewed as a cleaner alternative to conventional fossil-fuel burning vehicles, especially for local pollutant (nitrogen oxides [NOx], sulfur oxides [SOx], and particulate matter with diameters less than 2.5 and 10 μm [PM2.5 and PM10]) and CO2 emissions. However, LIBs are known to have their own energy and environmental challenges. This study focuses on LIBs made...
Latest Results for Mitigation and Adaptation Strategies for Global Change
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Metabolomics combined with network pharmacology exploration reveals the modulatory properties of Astragali Radix extract in the treatment of liver fibrosis
Abstract Background Astragali Radix (AR) is widely-used for improving liver fibrosis, but, the mechanism of action has not been systematically explained. This study aims to investigate the mechanism of AR intervention in liver fibrosis based on comprehensive metabolomics combined with network pharmacology approach. Materials and methods UPLC–Q-TOF/MS...
Latest Results for Chinese Medicine
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Dissection of the molecular targets and signaling pathways of Guzhi Zengsheng Zhitongwan based on the analysis of serum proteomics
Abstract Background Guzhi Zengsheng Zhitongwan (GZZSZTW) is an effective formula of traditional Chinese herbal medicine and has been widely applied in the treatment of joint diseases for many years. The aim of this study was to dissect the molecular targets and signaling pathways of Guzhi Zengsheng Zhitongwan based on the analysis of serum proteomics. Methods ...
Latest Results for Chinese Medicine
17h
Potential early clinical stage colorectal cancer diagnosis using a proteomics blood test panel
Abstract Background One of the most significant challenges in colorectal cancer (CRC) management is the use of compliant early stage population-based diagnostic tests as adjuncts to confirmatory colonoscopy. Despite the near curative nature of early clinical stage surgical resection, mortality remains unacceptably high—as the majority of patients diagnosed by faecal haemoglobin followed by colonoscopy occur at latter stages. Additionally,...
Latest Results for Clinical Proteomics
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Authors’ response to letter to the editor: “Meta-analysis on vitamin C and the common cold in children may be misleading”
Latest Results for European Journal of Clinical Pharmacology
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Local pharma initiative adds chief strategy officer and global partner
Adding global consortium members will give the network valuable insights on medication waste. (Source: bizjournals.com Health Care:Biotechnology headlines)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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1h
Nashville firm opens first Ohio addiction treatment center in Dayton region
A Nashville-based health care company specializing in addiction treatment centers has opened its first Ohio facility in the Dayton region. SaVida Health, founded in 2010 in response to the growing opioid epidemic in the U.S., opened a treatment center Aug. 26 at 4421 Roosevelt Road in Middletown.  SaVida offers evidence-based, integrated treatment including counseling, case management, medical care and toxicology testing. It is dri ven by the recognition that addiction is a disease, not a...
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9h
Report: Here's how much is spent on health care in Florida
A new report from TheSeniorList shows that Florida ranks No. 22 in the United States for the most money spent on health care annually. The average person in Florida with private health insurance spends an average of $5,616 per year on health care, the report shows. That's below the national average of $5,640.78. Residents in Hawaii spend the least, at $3,626 per person. Alaska tops the list with the highest health care spend at $7,469. Florida also has the lowest percentage increase in...
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9h
Georgia's opiod lawsuit headed to business court
A lawsuit the state of Georgia filed earlier this year against manufacturers and distributors of prescription opioids is being transferred to the Business Case Division in Gwinnett County Superior Court. The suit, one of a number of similar cases states have been bringing across the country, claims drug companies have increased demand for their addictive products by engaging in a campaign of deceptive and unfair marketing practices meant to downplay the risks of opioids while inflating their...
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9h
Nursing home tied to alleged fraud sells for $20M
Federal prosecutors placed a lis pendens on this property in 2016. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
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9h
Real estate firm adds to its collection of Stanford buildings
Eight months after a $100 million megapurchase in Stanford Research Park, a Pasadena-based real estate firm has added another building to its collection in the same campus. The Mercury News reports that Alexandria Real Estate Equities Inc. has bought the office building at 3160 Porter Drive in Palo Alto for about $97 million in a deal that closed Aug. 12, citing Santa Clara County property records. The 96,500-square-foot, Class A office building was owned by Stanfo rd University, and Stanford...
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9h
FDA fast tracks AstraZeneca diabetes drug
Farxiga is being given a speedy review prevent heart and kidney failure prevention for those with chronic kidney disease (Source: PharmaManufacturing.com)
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9h
Former Speaker of the House Paul Ryan joins SHINE Medical board
Former Wisconsin Congressman and Speaker of the House  Paul Ryan has joined the board of directors at SHINE Medical Technologies LLC, a Janesville-based nuclear medicine company that's setting up the commercial production of a radioisotope used in medical imaging. Ryan was U.S. House Speaker when the Republican easily won re-election in 2016 for hi s ninth term in the House of Representatives, representing Wisconsin's 1st Congressional District, which includes Janesville, since 1998. He chose…...
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9h
Edited genes are not ready to be inherited
DNA changes should benefit patients but not yet their descendants (Source: FT.com - Drugs and Healthcare)
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9h
Report: Here's how much is spent on health care in Florida
A new report from TheSeniorList shows that Florida ranks No. 22 in the United States for the most money spent on health care annually. The average person in Florida with private health insurance spends an average of $5,616 per year on health care, the report shows. That's below the national average of $5,640.78. Residents in Hawaii spend the least, at $3,626 per person. Alaska tops the list with the highest health care spend at $7,469. Florida also has the lowest percentage increase in...
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9h
J&J verdict hits share prices across opioid industry
Teva and Endo International tumble after Oklahoma judge’s ruling (Source: FT.com - Drugs and Healthcare)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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9h
Mason firm adds former Assurex Health executive to C-suite, hints at IPO
Genetesis, a Mason startup that ’s developing medical devices to detect heart disease and is considering an initial public offering of stock, has hired a former Assurex Health executive as chief business officer. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
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KU Health sets opening date for KCK behaviorial health campus
After a yearlong and roughly $61 million renovation, The University of Kansas Health System will admit its first patients to its new behavioral and psychiatric facility on Sept. 4. KU Health's Strawberry Hill Campus, which is located at the southeast corner of Fifth Street and Minnesota Avenue in Kansas City, Kan., has renovated a building that once housed the Environmental Protection Agency and its 600 employees. Just more than half of the 220,000-square-foot building faci lity — 112,000...
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9h
Nashville firm opens first Ohio addiction treatment center in Greater Cincinnati
A Nashville-based health care company specializing in addiction treatment centers has opened its first Ohio facility in Greater Cincinnati. SaVida Health, founded in 2010 in response to the growing opioid epidemic in the U.S., opened a treatment center Aug. 26 at 4421 Roosevelt Road in Middletown.  SaVida offers evidence-based, integrated treatment including counseling, case management, medical care and toxicology testing. It is dri ven by the recognition that addiction is a disease, not a...
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9h
Boehringer pharma head to step down
Allan Hillgrove, the board member responsible for the company's human pharma and biopharma business, is set to retire at the end of the year as the rest of the Boehringer Ingelheim board is getting shaken up (Source: PharmaManufacturing.com)
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IP Explained: Three forms of IP protections for medicines
Intellectual property (IP) protections for the biopharmaceutical sector provide incentives that help to promote the discovery and development of life-saving medicines for patients and foster a competitive market for generic and biosimilar medicines. There are three forms of IP protections critical to biopharmaceutical development, and although they work together in a complementary fashion, each is distinct and governed by different statutory provisions. (Source: The Catalyst)MedWorm Message: If you...
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9h
Gene editing: even Crispr 
Tighter regulation is inevitable; the only question is what form it will take (Source: FT.com - Drugs and Healthcare)
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9h
Medicare ’s New Plan Finder Could Boost Insurers' Advantage Enrollment
Myriad upgrades to the way seniors choose Medicare health plans and drug coverage could boost the already fast-growing private Medicare Advantage enrollment. (Source: Forbes.com Healthcare News)
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The Most Expensive Medicare Patients Aren't Who You Think
Over half of Medicare spending is concentrated in 10% of patients. So who are those patients and what expenses are they racking up? It ’s not who or what I expected. (Source: Forbes.com Healthcare News)
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9h
Oklahoma judge rules against J & amp;J in landmark trial
A judge in Oklahoma has ordered Johnson& Johnson to pay $572 million in damages for its role in the opioid epidemic. (Source: PharmaManufacturing.com)
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Blockbuster-bound Lilly drug wins another FDA nod
Eli Lilly ’s Taltz has been given the go-ahead for a new indication, which could help propel the drug to blockbuster status. (Source: PharmaManufacturing.com)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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9h
EBR Systems Closes $30M in New Funding, John McCutcheon Joins Company as President and CEO
SUNNYVALE, Calif., Aug. 27, 2019 -- (Healthcare Sales & Marketing Network) -- EBR Systems, Inc., developer of the world's only wireless cardiac pacing system for heart failure, today announced it has closed $30M in new funding to complete enrollment of it... Devices, Cardiology, Venture Capital, Personnel EBR Systems, cardiac pacing, Cardiac Resynchronization Therapy, WISE CRT (Source: HSMN NewsFeed)
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9h
PIONYR Immunotherapeutics Announces Key Leadership Team Addition and Clinical Candidates Targeting Tumor-Associated Macrophages
Alicia Levey, Ph.D., joins as Senior Vice President and Chief Business Officer Two first-in-class Myeloid Tuning antibodies with novel mechanisms in the tumor microenvironment headed for the clinic SOUTH SAN FRANCISCO, Aug. 27, 2019 -- (Healthcare S... Biopharmaceuticals, Oncology, Personnel PIONYR Immunotherapeutics, Myeloid Tuning (Source: HSMN NewsFeed)
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Lipocine Announces Trial Date in Lipocine's Infringement Lawsuit Against Clarus Therapeutics and Will Seek a Permanent Injunction
SALT LAKE CITY, Aug. 27, 2019 -- (Healthcare Sales & Marketing Network) -- Lipocine Inc. (NASDAQ: LPCN), a clinical-stage biopharmaceutical company focused on metabolic and endocrine disorders, announced today that the U.S. District Court of Delaware has ... Biopharmaceuticals, Litigation Lipocine, Clarus , JATENZO (Source: HSMN NewsFeed)
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Machavert Pharmaceuticals Signs Exclusive License Agreement to Control RAL GTPase Inhibitors against KRAS Cancers
Machavert obtains worldwide exclusive license to small molecule RAL GTPase inhibitors to treat KRAS cancers AURORA, Colo., Aug. 27, 2019 -- (Healthcare Sales & Marketing Network) -- Machavert Pharmaceuticals, a preclinical stage pharmaceutical company ... Biopharmaceuticals, Oncology, Licensing Machavert Pharmaceuticals, KRAS , precision medicine (Source: HSMN NewsFeed)
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Telehealth Has An Awareness Problem
Telehealth companies, health plans and health systems are figuring out the best way to reach out to consumers and promote video visits with doctors. (Source: Forbes.com Healthcare News)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
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9h
Polyunsaturated Fatty Acids Have Little, No Impact on Diabetes
TUESDAY, Aug. 27, 2019 -- Polyunsaturated fatty acids (PUFA) have little to no effect on the prevention or treatment of type 2 diabetes mellitus, according to a review published online Aug. 21 in The BMJ. Tracey J. Brown, from Norwich Medical School... (Source: Drugs.com - Pharma News)
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9h
Few Oncologists Suggest Health Promotion to Cancer Survivors
TUESDAY, Aug. 27, 2019 -- Few oncologists and specialists recommend health promotion to cancer survivors, according to a study published online Aug. 26 in Cancer. Noting that guidelines encourage health promotion counseling for cancer survivors,... (Source: Drugs.com - Pharma News)
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9h
Combo Tx May Improve Disease Control for Some in Early RA
TUESDAY, Aug. 27, 2019 -- For patients with early rheumatoid arthritis (RA) and high disease activity, the combination of a tumor necrosis factor (TNF) or non-TNF biologic with methotrexate improves disease control, remission, and functional... (Source: Drugs.com - Pharma News)
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9h
Prenatal Exposure to OMT Does Not Worsen Neonatal Outcomes
TUESDAY, Aug. 27, 2019 -- Exposure to opioid maintenance treatment (OMT) in the womb does not seem to cause additional harm to newborns, according to a study published online Aug. 14 in Pharmacology Research& Perspectives. Marte Handal, Ph.D.,... (Source: Drugs.com - Pharma News)
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9h
Survival Poor for Elderly Admitted to Long-Term Acute Care Setting
TUESDAY, Aug. 27, 2019 -- Hospitalized older adults transferred to a long-term acute care (LTAC) hospital have poor survival, with more than one-third never returning home, according to a study published online Aug. 26 in the Journal of the American... (Source: Drugs.com - Pharma News)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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Prices Spike for Drugs Used to Treat Multiple Sclerosis
TUESDAY, Aug. 27, 2019 -- From 2006 to 2016, the prices of self-administered disease-modifying therapies (DMTs) for multiple sclerosis increased, according to a study published online Aug. 26 in JAMA Neurology. Alvaro San-Juan-Rodriguez, Pharm.D.,... (Source: Drugs.com - Pharma News)
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9h
Smaller & #43; Larger Infarctions May Escalate Later Cognitive Decline
TUESDAY, Aug. 27, 2019 -- The combination of smaller and larger infarctions detected in stroke-free individuals in middle age is associated with substantial cognitive decline later in life, according to a study published online Aug. 27 in the Annals... (Source: Drugs.com - Pharma News)
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