Κυριακή 11 Αυγούστου 2019


  Characterisation of flexor digitorum profundus, flexor digitorum superficialis and extensor digitorum communis by electrophoresis and immunohistochemical analysis of myosin heavy chain isoforms in older men
Publication date: Available online 10 August 2019Source: Annals of Anatomy - Anatomischer AnzeigerAuthor(s): Marija Meznaric, Andrej ČarniAbstractIntroductionFew data exist on the fiber type composition of the extrinsic finger muscles. The aim of the present study was to describe myosin heavy chain (MyHC) composition of flexor digitorum profundus (FDP), flexor digitorum superficialis (FDS) and extensor digitorum communis (EDC). MyHC composition is relevant for whole muscle contractile performance...
ScienceDirect Publication: Annals of Anatomy - Anatomischer Anzeiger
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Editorial Board
Publication date: September 2019Source: Annals of Anatomy - Anatomischer Anzeiger, Volume 225Author(s):
ScienceDirect Publication: Annals of Anatomy - Anatomischer Anzeiger
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Development of an e-learning prototype for assessing occupational stress-related disorders: a qualitative study.
Related ArticlesDevelopment of an e-learning prototype for assessing occupational stress-related disorders: a qualitative study. BMC Med Educ. 2019 Aug 09;19(1):305 Authors: Omvlee L, van der Molen HF, Te Pas E, Frings-Dresen MHW Abstract BACKGROUND: Occupational stress-related disorders are complex to diagnose and prevent, due to their multifactorial origin. We developed an e-learning programme aimed at supporting occupational physicians when diagnosing...
pubmed: "bmc med educ"[jour]
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Evaluation of Constructing Care Collaboration - nurturing empathy and peer-to-peer learning in medical students who participate in voluntary structured service learning programmes for migrant workers.
Related ArticlesEvaluation of Constructing Care Collaboration - nurturing empathy and peer-to-peer learning in medical students who participate in voluntary structured service learning programmes for migrant workers. BMC Med Educ. 2019 Aug 08;19(1):304 Authors: Sin D, Chew T, Chia TK, Ser JS, Sayampanathan A, Koh G Abstract BACKGROUND: Experiential learning through service provides opportunities to nurture and practice empathy. Of growing concern, studies...
pubmed: "bmc med educ"[jour]
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Practice scope and job confidence of two-year trained optometry technicians in Eritrea.
Related ArticlesPractice scope and job confidence of two-year trained optometry technicians in Eritrea. BMC Med Educ. 2019 Aug 07;19(1):303 Authors: Gyawali R, Bhayal BK Abstract BACKGROUND: A two-year optometry technician (OT) training was started in Eritrea in 2009 to fulfill the immediate human resource needs in providing refractive, dispensing and primary eye care services in vision centers. This study aimed to assess the current practice pattern...
pubmed: "bmc med educ"[jour]
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Infant, neonatal, and postneonatal mortality trends in a disaster region and in Japan, 2002-2012: a multi-attribute compositional study.
Related ArticlesInfant, neonatal, and postneonatal mortality trends in a disaster region and in Japan, 2002-2012: a multi-attribute compositional study. BMC Public Health. 2019 Aug 09;19(1):1085 Authors: Tashiro A, Yoshida H, Okamoto E Abstract BACKGROUND: The reductions achieved in infant mortality in Japan are globally regarded as remarkable. However, no studies in Japan have classified infant mortality trends into neonatal and postneonatal or considered...
pubmed: "bmc public health"[...
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Project ESTEEM protocol: a randomized controlled trial of an LGBTQ-affirmative treatment for young adult sexual minority men's mental and sexual health.
Related ArticlesProject ESTEEM protocol: a randomized controlled trial of an LGBTQ-affirmative treatment for young adult sexual minority men's mental and sexual health. BMC Public Health. 2019 Aug 09;19(1):1086 Authors: Pachankis JE, McConocha EM, Reynolds JS, Winston R, Adeyinka O, Harkness A, Burton CL, Behari K, Sullivan TJ, Eldahan AI, Esserman DA, Hatzenbuehler ML, Safren SA Abstract BACKGROUND: Young gay and bisexual men disproportionately experience...
pubmed: "bmc public health"[...
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The effectiveness of financial intervention strategies for reducing caesarean section rates: a systematic review.
Related ArticlesThe effectiveness of financial intervention strategies for reducing caesarean section rates: a systematic review. BMC Public Health. 2019 Aug 09;19(1):1080 Authors: Yu Y, Lin F, Dong W, Li H, Zhang X, Chen C Abstract BACKGROUND: The increasing trend of Caesarean section (CS) in childbirth has become a global public health challenge. Previous studies have proposed financial intervention strategies for reducing CS rates by limiting caesarean...
pubmed: "bmc public health"[...
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Relationships between area-level socioeconomic status and urbanization with active transportation, independent mobility, outdoor time, and physical activity among Canadian children.
Related ArticlesRelationships between area-level socioeconomic status and urbanization with active transportation, independent mobility, outdoor time, and physical activity among Canadian children. BMC Public Health. 2019 Aug 09;19(1):1082 Authors: Delisle Nyström C, Barnes JD, Blanchette S, Faulkner G, Leduc G, Riazi NA, Tremblay MS, Trudeau F, Larouche R Abstract BACKGROUND: Active transportation (AT), independent mobility (IM), and outdoor time are...
pubmed: "bmc public health"[...
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The double burden of malnutrition in a rural health and demographic surveillance system site in South Africa: a study of primary schoolchildren and their mothers.
Related ArticlesThe double burden of malnutrition in a rural health and demographic surveillance system site in South Africa: a study of primary schoolchildren and their mothers. BMC Public Health. 2019 Aug 09;19(1):1087 Authors: Modjadji P, Madiba S Abstract BACKGROUND: In South Africa, the occurrence of the double burden of malnutrition is on the rise at a household level predisposing children and their mothers to negative health outcomes. However,...
pubmed: "bmc public health"[...
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A study protocol for a randomised controlled trial evaluating the use of information communication technology (WhatsApp/WeChat) to deliver brief motivational interviewing (i-BMI) in promoting smoking cessation among smokers with chronic diseases.
Related ArticlesA study protocol for a randomised controlled trial evaluating the use of information communication technology (WhatsApp/WeChat) to deliver brief motivational interviewing (i-BMI) in promoting smoking cessation among smokers with chronic diseases. BMC Public Health. 2019 Aug 09;19(1):1083 Authors: Li WHC, Ho KY, Lam KKW, Wang MP, Cheung DYT, Ho LLK, Xia W, Lam TH Abstract BACKGROUND: The recent development of smoking cessation interventions...
pubmed: "bmc public health"[...
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Cost-effectiveness of childhood pneumococcal vaccination program in Ethiopia: results from a quasi-experimental evaluation.
Related ArticlesCost-effectiveness of childhood pneumococcal vaccination program in Ethiopia: results from a quasi-experimental evaluation. BMC Public Health. 2019 Aug 09;19(1):1078 Authors: Kebede TT, Svensson M, Addissie A, Trollfors B, Andersson R Abstract BACKGROUND: Ethiopia was among the 15 countries that, together accounted for 64% of the world's severe episodes of pneumonia among children below the age of 5 in 2011. To reduce this burden, the...
pubmed: "bmc public health"[...
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Sports-based recreation as a means to address social inequity in health: why, when, where, who, what, and how.
Related ArticlesSports-based recreation as a means to address social inequity in health: why, when, where, who, what, and how. BMC Public Health. 2019 Aug 09;19(1):1084 Authors: Elsborg P, Nielsen G, Klinker CD, Melby PS, Christensen JH, Bentsen P Abstract The rising global burden of noncommunicable diseases (NCDs) among people with low socioeconomic status (SES) has heightened awareness of the need for primary prevention programs in low-SES neighborhoods....
pubmed: "bmc public health"[...
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Homelessness and self-rated health: evidence from a national survey of homeless people in Spain.
Related ArticlesHomelessness and self-rated health: evidence from a national survey of homeless people in Spain. BMC Public Health. 2019 Aug 09;19(1):1081 Authors: Fajardo-Bullón F, Esnaola I, Anderson I, Benjaminsen L Abstract BACKGROUND: Internationally, acute homelessness is commonly associated with complex health and social care needs. While homelessness can be understood as an outcome of structural housing exclusion requiring housing led solutions,...
pubmed: "bmc public health"[...
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Association between dietary inflammatory index and bone density in lactating women at 6 months postpartum: a longitudinal study.
Related ArticlesAssociation between dietary inflammatory index and bone density in lactating women at 6 months postpartum: a longitudinal study. BMC Public Health. 2019 Aug 09;19(1):1076 Authors: Zhou Y, Zhu X, Zhang M, Li Y, Liu W, Huang H, Xu Y Abstract BACKGROUND: Chronic inflammation contributes to the risk of osteoporosis and fracture. Dietary Inflammatory Index (DII), a novel method appraising the inflammatory potential of diet, has been utilized...
pubmed: "bmc public health"[...
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Public health effects of gambling - debate on a conceptual model.
Related ArticlesPublic health effects of gambling - debate on a conceptual model. BMC Public Health. 2019 Aug 09;19(1):1077 Authors: Latvala T, Lintonen T, Konu A Abstract BACKGROUND: Gambling for money is a popular leisure time activity in most countries, which has major social and economic impacts not only affecting the gambler, but his/her significant others, and the society. Gambling impact studies can help researchers and policymakers compare the...
pubmed: "bmc public health"[...
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Work-related risk factors and the prevalence of low back pain among low wage workers: results from a cross-sectional study.
Related ArticlesWork-related risk factors and the prevalence of low back pain among low wage workers: results from a cross-sectional study. BMC Public Health. 2019 Aug 08;19(1):1072 Authors: Wami SD, Abere G, Dessie A, Getachew D Abstract BACKGROUND: Low back pain, the most commonly reported musculoskeletal problem, is a major burden on individuals, health systems and social care systems with the indirect cost being predominant. It results in disability,...
pubmed: "bmc public health"[...
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A qualitative study of the process of adoption, implementation and enforcement of smoke-free policies in privately-owned affordable housing.
Related ArticlesA qualitative study of the process of adoption, implementation and enforcement of smoke-free policies in privately-owned affordable housing. BMC Public Health. 2019 Aug 08;19(1):1071 Authors: Kegler MC, Lebow-Skelley E, Lea J, Haardörfer R, Lefevre A, Diggs P, Herndon S Abstract BACKGROUND: Household smoke-free home rules cannot fully protect nonsmokers from secondhand smoke (SHS) if they live in multi-unit housing (MUH). Instead, property-level...
pubmed: "bmc public health"[...
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Factors affecting dental service utilisation among older Singaporeans eligible for subsidized dental care - a qualitative study.
Related ArticlesFactors affecting dental service utilisation among older Singaporeans eligible for subsidized dental care - a qualitative study. BMC Public Health. 2019 Aug 08;19(1):1075 Authors: Mittal R, Wong ML, Koh GC, Ong DLS, Lee YH, Tan MN, Allen PF Abstract BACKGROUND: The World Health Organization has highlighted the paucity of research into the oral health needs of older adults. In Singapore, until recently, publically funded/subsidized oral...
pubmed: "bmc public health"[...
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Examining the association of changes in minimum wage with health across race/ethnicity and gender in the United States.
Related ArticlesExamining the association of changes in minimum wage with health across race/ethnicity and gender in the United States. BMC Public Health. 2019 Aug 08;19(1):1069 Authors: Narain KDC, Zimmerman FJ Abstract BACKGROUND: The minimum wage creates both winners (through wage increases) and-potentially-losers (through job losses). Research on the health effects of minimum wage policies has been sparse, particularly across gender and among racial/ethnic...
pubmed: "bmc public health"[...
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Participant engagement with a UK community-based preschool childhood obesity prevention programme: a focused ethnography study.
Related ArticlesParticipant engagement with a UK community-based preschool childhood obesity prevention programme: a focused ethnography study. BMC Public Health. 2019 Aug 08;19(1):1074 Authors: Burton W, Twiddy M, Sahota P, Brown J, Bryant M Abstract BACKGROUND: Children's centres in the UK provide a setting for public health programmes; offering support to families living in the most disadvantaged areas where obesity prevalence is at its highest. Health,...
pubmed: "bmc public health"[...
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Effects of helmet nonuse and seating position on patterns and severity of injuries in child motorcycle passengers.
Related ArticlesEffects of helmet nonuse and seating position on patterns and severity of injuries in child motorcycle passengers. BMC Public Health. 2019 Aug 08;19(1):1070 Authors: Fan HP, Chiu WT, Lin MR Abstract BACKGROUND: A prospective study was conducted to investigate the effects of helmet nonuse and seating position on patterns and severity of motorcycle injuries among child passengers in Taiwan. METHODS: In total, 305 child passengers...
pubmed: "bmc public health"[...
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Overall gestational weight gain mediates the relationship between maternal and child obesity.
Related ArticlesOverall gestational weight gain mediates the relationship between maternal and child obesity. BMC Public Health. 2019 Aug 07;19(1):1062 Authors: Josey MJ, McCullough LE, Hoyo C, Williams-DeVane C Abstract BACKGROUND: Approximately 17% of children in the U.S. are obese. Children that are overweight or obese are also more likely to be obese as adults and suffer from various chronic diseases and premature death. Maternal obesity can affect...
pubmed: "bmc public health"[...
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Door - to - door immunization strategy for improving access and utilization of immunization Services in Hard-to-Reach Areas: a case of Migori County, Kenya.
Related ArticlesDoor - to - door immunization strategy for improving access and utilization of immunization Services in Hard-to-Reach Areas: a case of Migori County, Kenya. BMC Public Health. 2019 Aug 07;19(1):1064 Authors: Shikuku DN, Muganda M, Amunga SO, Obwanda EO, Muga A, Matete T, Kisia P Abstract BACKGROUND: Access to quality essential healthcare services and vaccines for all is key to achieving universal health coverage. Inequities driven by...
pubmed: "bmc public health"[...
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Prevalence and risk factors of soil-transmitted helminthiasis among school children living in an agricultural area of North Sumatera, Indonesia.
Related ArticlesPrevalence and risk factors of soil-transmitted helminthiasis among school children living in an agricultural area of North Sumatera, Indonesia. BMC Public Health. 2019 Aug 07;19(1):1066 Authors: Pasaribu AP, Alam A, Sembiring K, Pasaribu S, Setiabudi D Abstract BACKGROUND: Soil-transmitted helminth infection (STH) is one of the neglected tropical disease that affects approximately 2 billion people globally. School children represent...
pubmed: "bmc public health"[...
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Meningococcal disease in Italy: public concern, media coverage and policy change.
Related ArticlesMeningococcal disease in Italy: public concern, media coverage and policy change. BMC Public Health. 2019 Aug 07;19(1):1061 Authors: Covolo L, Croce E, Moneda M, Zanardini E, Gelatti U, Schulz PJ, Ceretti E Abstract BACKGROUND: Between 2015 and 2017 six deaths due to meningitis in the Lombardy Region, Northern Italy, caught the attention of media and increased concern among the population, with a consequent increase in demand for vaccination....
pubmed: "bmc public health"[...
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Risk factors for depression in elderly diabetic patients and the effect of metformin on the condition.
Related ArticlesRisk factors for depression in elderly diabetic patients and the effect of metformin on the condition. BMC Public Health. 2019 Aug 07;19(1):1063 Authors: Chen F, Wei G, Wang Y, Liu T, Huang T, Wei Q, Ma G, Wang D Abstract BACKGROUND: At present, only a few studies have focused on the risk factors for depression in elderly diabetic patients, and there is little evidence for the effect of metformin in depressed elderly patients with diabetes...
pubmed: "bmc public health"[...
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Socioeconomic inequalities in non-communicable disease risk factors in Botswana: a cross-sectional study.
Related ArticlesSocioeconomic inequalities in non-communicable disease risk factors in Botswana: a cross-sectional study. BMC Public Health. 2019 Aug 07;19(1):1060 Authors: Keetile M, Navaneetham K, Letamo G, Rakgoasi SD Abstract BACKGROUND: The debate on socioeconomic inequalities in health dominates the research and policy agenda of many countries. The prevalence of non-communicable diseases (NCDs) is on the rise in recent years in Botswana. As a prevention...
pubmed: "bmc public health"[...
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Seasonality of physical activity and its association with socioeconomic and health factors among urban-dwelling adults of Kaunas, Lithuania.
Related ArticlesSeasonality of physical activity and its association with socioeconomic and health factors among urban-dwelling adults of Kaunas, Lithuania. BMC Public Health. 2019 Aug 07;19(1):1067 Authors: Dėdelė A, Miškinytė A, Andrušaitytė S, Nemaniūtė-Gužienė J Abstract BACKGROUND: Physical activity (PA) has been declining dramatically over time in many countries worldwide. The decrease of PA levels affects a person's health and quality of life...
pubmed: "bmc public health"[...
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Global comparison of cancer outcomes: standardization and correlation with healthcare expenditures.
Related ArticlesGlobal comparison of cancer outcomes: standardization and correlation with healthcare expenditures. BMC Public Health. 2019 Aug 07;19(1):1065 Authors: Choi HCW, Lam KO, Pang HHM, Tsang SKC, Ngan RKC, Lee AWM Abstract BACKGROUND: Cancer outcomes vary widely among different countries. However, comparisons of cost-effectiveness and cost-efficiency of different systems are complex because the incidences of different cancers vary across countries...
pubmed: "bmc public health"[...
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Indicator-based public health monitoring in old age in OECD member countries: a scoping review.
Related ArticlesIndicator-based public health monitoring in old age in OECD member countries: a scoping review. BMC Public Health. 2019 Aug 07;19(1):1068 Authors: Grube MM, Möhler R, Fuchs J, Gaertner B, Scheidt-Nave C Abstract BACKGROUND: The scoping review was conducted as part of the project "Improving Health Monitoring in Old Age" (IMOA) which aims at developing a conceptual framework with key indicators for a public health monitoring of the population...
pubmed: "bmc public health"[...
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Changing health behaviors using financial incentives: a review from behavioral economics.
Related ArticlesChanging health behaviors using financial incentives: a review from behavioral economics. BMC Public Health. 2019 Aug 07;19(1):1059 Authors: Vlaev I, King D, Darzi A, Dolan P Abstract BACKGROUND: Incentives are central to economics and are used across the public and private sectors to influence behavior. Recent interest has been shown in using financial incentives to promote desirable health behaviors and discourage unhealthy ones. ...
pubmed: "bmc public health"[...
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Epithelioid Malignant Peripheral Nerve Sheath Tumor (Epithelioid-MPNST) Presenting as Bleeding Rectal Polyp: A Case Report with Systematic Literature Review.
Related ArticlesEpithelioid Malignant Peripheral Nerve Sheath Tumor (Epithelioid-MPNST) Presenting as Bleeding Rectal Polyp: A Case Report with Systematic Literature Review. Am J Case Rep. 2019 Aug 10;20:1175-1181 Authors: Patra S, Ayyanar P, Padhi S, Purkait S, Muduly DK, Samal SC Abstract BACKGROUND Malignant peripheral nerve sheath tumor (MPNST) with pure epithelioid histology MPNST (epithelioid-MPNST) is a distinctly rare variant of MPNST described...
pubmed: "am j case rep"[jour...
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Parathyroidectomy as a Cure for Calciphylaxis in a Non-Dialysis Chronic Kidney Disease Patient?
Related ArticlesParathyroidectomy as a Cure for Calciphylaxis in a Non-Dialysis Chronic Kidney Disease Patient? Am J Case Rep. 2019 Aug 09;20:1170-1174 Authors: Nasr R, Ghazanfar H Abstract BACKGROUND Calciphylaxis is a rare and fatal systemic disease which most commonly occurs in patients with end-stage renal disease. It is a poorly understood vascular calcification with unclear pathology that leads to vascular compromise due to vascular occlusion with...
pubmed: "am j case rep"[jour...
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Complications of Insufficient Dura and Blood Loss During Surgical Intervention in Shprintzen-Goldberg Syndrome: A Case Report.
Related ArticlesComplications of Insufficient Dura and Blood Loss During Surgical Intervention in Shprintzen-Goldberg Syndrome: A Case Report. Am J Case Rep. 2019 Aug 08;20:1159-1169 Authors: O'Dougherty GR, Fulkerson DH, Kern M, Haldar K, Calhoun B Abstract BACKGROUND Shprintzen-Goldberg syndrome (SGS) is an extremely rare collagenopathy, most often caused by autosomal-dominant mutations in the SKI proto-oncogene, which is a component of the transforming...
pubmed: "am j case rep"[jour...
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Commentary on "Surgical management and outcome of grade-C pancreatic fistulas after pancreaticoduodenectomy: A retrospective multicenter cohort study".
Related ArticlesCommentary on "Surgical management and outcome of grade-C pancreatic fistulas after pancreaticoduodenectomy: A retrospective multicenter cohort study". Int J Surg. 2019 Aug 07;: Authors: Molmenti EP, Coppa GF PMID: 31400505 [PubMed - as supplied by publisher]
International Journal of Surgery
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Risk Factors for Recurrence after Anal Fistula Surgery: A Meta-analysis.
Related ArticlesRisk Factors for Recurrence after Anal Fistula Surgery: A Meta-analysis. Int J Surg. 2019 Aug 07;: Authors: Mei Z, Wang Q, Zhang Y, Liu P, Ge M, Du P, Yang W, He Y Abstract BACKGROUND: Despite a burgeoning literature during the last two decades regarding perioperative risk management of anal fistula, little is known about its risk factors that influence postoperative recurrence. We performed a meta-analysis to summarize and assess the...
International Journal of Surgery
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Structured introduction of retroperitoneoscopic donor nephrectomy provides a high level of safety and reduces the physical burden for the donor compared to an anterior mini incision: a cohort study.
Related ArticlesStructured introduction of retroperitoneoscopic donor nephrectomy provides a high level of safety and reduces the physical burden for the donor compared to an anterior mini incision: a cohort study. Int J Surg. 2019 Aug 07;: Authors: Koch M, Kroencke S, Li J, Wiessner C, Nashan B Abstract INTRODUCTION: A major goal in living donor kidney transplantation is to reduce the physical burden for the donor. Key-hole surgery for donor nephrectomy...
International Journal of Surgery
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Use of endoscopic vein harvesting (EVH) during coronary artery bypass grafting in United Kingdom: The EVH Survey?
Related ArticlesUse of endoscopic vein harvesting (EVH) during coronary artery bypass grafting in United Kingdom: The EVH Survey? Int J Surg. 2019 Aug 06;: Authors: Soni MK, Williams L, Raja SG Abstract OBJECTIVE: Endoscopic vein harvesting (EVH) is growing in popularity and is the method of choice in many centers worldwide as it is associated with lower complication rates compared to the open vein harvesting. The aim of this study was to determine the...
International Journal of Surgery
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Ensuring safe surgical care across resource settings via surgical outcomes data & quality improvement initiatives.
Related ArticlesEnsuring safe surgical care across resource settings via surgical outcomes data & quality improvement initiatives. Int J Surg. 2019 Aug 05;: Authors: Eyob B, Boeck MA, FaSiOen P, Cawich S, Kluger MD Abstract Staggering statistics regarding the global burden of disease due to lack of surgical care worldwide has been gaining attention in the global health literature over the last 10 years. The Lancet Commission on Global Surgery reported...
International Journal of Surgery
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Classifying fishing behavioral diversity using high-frequency movement data.
Related ArticlesClassifying fishing behavioral diversity using high-frequency movement data. Proc Natl Acad Sci U S A. 2019 Aug 09;: Authors: O'Farrell S, Chollett I, Sanchirico JN, Perruso L Abstract Effective management of social-ecological systems (SESs) requires an understanding of human behavior. In many SESs, there are hundreds of agents or more interacting with governance and regulatory institutions, driving management outcomes through collective...
pubmed: "proc natl acad sci ...
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Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation.
Related ArticlesGlucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation. Proc Natl Acad Sci U S A. 2019 Aug 09;: Authors: Provençal N, Arloth J, Cattaneo A, Anacker C, Cattane N, Wiechmann T, Röh S, Ködel M, Klengel T, Czamara D, Müller NS, Lahti J, PREDO team, Räikkönen K, Pariante CM, Binder EB Abstract Prenatal stress exposure is associated with risk for psychiatric disorders later...
pubmed: "proc natl acad sci ...
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Distance-based protein folding powered by deep learning.
Related ArticlesDistance-based protein folding powered by deep learning. Proc Natl Acad Sci U S A. 2019 Aug 09;: Authors: Xu J Abstract Direct coupling analysis (DCA) for protein folding has made very good progress, but it is not effective for proteins that lack many sequence homologs, even coupled with time-consuming conformation sampling with fragments. We show that we can accurately predict interresidue distance distribution of a protein by deep learning,...
pubmed: "proc natl acad sci ...
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Nanoscale oxygen defect gradients in UO2+x surfaces.
Related ArticlesNanoscale oxygen defect gradients in UO2+x surfaces. Proc Natl Acad Sci U S A. 2019 Aug 09;: Authors: Spurgeon SR, Sassi M, Ophus C, Stubbs JE, Ilton ES, Buck EC Abstract Oxygen defects govern the behavior of a range of materials spanning catalysis, quantum computing, and nuclear energy. Understanding and controlling these defects is particularly important for the safe use, storage, and disposal of actinide oxides in the nuclear fuel...
pubmed: "proc natl acad sci ...
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Controlling the material properties and rRNA processing function of the nucleolus using light.
Related ArticlesControlling the material properties and rRNA processing function of the nucleolus using light. Proc Natl Acad Sci U S A. 2019 Aug 09;: Authors: Zhu L, Richardson TM, Wacheul L, Wei MT, Feric M, Whitney G, Lafontaine DLJ, Brangwynne CP Abstract The nucleolus is a prominent nuclear condensate that plays a central role in ribosome biogenesis by facilitating the transcription and processing of nascent ribosomal RNA (rRNA). A number of studies...
pubmed: "proc natl acad sci ...
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The Hsp70 chaperone is a major player in stress-induced transposable element activation.
Related ArticlesThe Hsp70 chaperone is a major player in stress-induced transposable element activation. Proc Natl Acad Sci U S A. 2019 Aug 09;: Authors: Cappucci U, Noro F, Casale AM, Fanti L, Berloco M, Alagia AA, Grassi L, Le Pera L, Piacentini L, Pimpinelli S Abstract Previous studies have shown that heat shock stress may activate transposable elements (TEs) in Drosophila and other organisms. Such an effect depends on the disruption of a chaperone...
pubmed: "proc natl acad sci ...
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ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer.
Related ArticlesARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer. Proc Natl Acad Sci U S A. 2019 Aug 09;: Authors: Hashimoto S, Furukawa S, Hashimoto A, Tsutaho A, Fukao A, Sakamura Y, Parajuli G, Onodera Y, Otsuka Y, Handa H, Oikawa T, Hata S, Nishikawa Y, Mizukami Y, Kodama Y, Murakami M, Fujiwara T, Hirano S, Sabe H Abstract Although KRAS and TP53 mutations are...
pubmed: "proc natl acad sci ...
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Long noncoding RNAs are involved in multiple immunological pathways in response to vaccination.
Related ArticlesLong noncoding RNAs are involved in multiple immunological pathways in response to vaccination. Proc Natl Acad Sci U S A. 2019 Aug 09;: Authors: de Lima DS, Cardozo LE, Maracaja-Coutinho V, Suhrbier A, Mane K, Jeffries D, Silveira ELV, Amaral PP, Rappuoli R, de Silva TI, Nakaya HI Abstract Understanding the mechanisms of vaccine-elicited protection contributes to the development of new vaccines. The emerging field of systems vaccinology...
pubmed: "proc natl acad sci ...
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Second harmonic generation detection of Ras conformational changes and discovery of a small molecule binder.
Related ArticlesSecond harmonic generation detection of Ras conformational changes and discovery of a small molecule binder. Proc Natl Acad Sci U S A. 2019 Aug 09;: Authors: Donohue E, Khorsand S, Mercado G, Varney KM, Wilder PT, Yu W, MacKerell AD, Alexander P, Van QN, Moree B, Stephen AG, Weber DJ, Salafsky J, McCormick F Abstract Second harmonic generation (SHG) is an emergent biophysical method that sensitively measures real-time conformational change...
pubmed: "proc natl acad sci ...
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iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition.
Related ArticlesiASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition. Proc Natl Acad Sci U S A. 2019 Aug 08;: Authors: Chen S, Wu J, Zhong S, Li Y, Zhang P, Ma J, Ren J, Tan Y, Wang Y, Au KF, Siebold C, Bond GL, Chen Z, Lu M, Jones EY, Lu X Abstract The most frequently mutated protein in human cancer is p53, a transcription factor (TF) that regulates myriad genes instrumental in diverse cellular outcomes including growth...
pubmed: "proc natl acad sci ...
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The crystal structure of human microsomal triglyceride transfer protein.
Related ArticlesThe crystal structure of human microsomal triglyceride transfer protein. Proc Natl Acad Sci U S A. 2019 Aug 08;: Authors: Biterova EI, Isupov MN, Keegan RM, Lebedev AA, Sohail AA, Liaqat I, Alanen HI, Ruddock LW Abstract Microsomal triglyceride transfer protein (MTP) plays an essential role in lipid metabolism, especially in the biogenesis of very low-density lipoproteins and chylomicrons via the transfer of neutral lipids and the assembly...
pubmed: "proc natl acad sci ...
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MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers.
Related ArticlesMiR223-3p promotes synthetic lethality in BRCA1-deficient cancers. Proc Natl Acad Sci U S A. 2019 Aug 08;: Authors: Srinivasan G, Williamson EA, Kong K, Jaiswal AS, Huang G, Kim HS, Schärer O, Zhao W, Burma S, Sung P, Hromas R Abstract Defects in DNA repair give rise to genomic instability, leading to neoplasia. Cancer cells defective in one DNA repair pathway can become reliant on remaining repair pathways for survival and proliferation....
pubmed: "proc natl acad sci ...
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Thylakoid localized bestrophin-like proteins are essential for the CO2 concentrating mechanism of Chlamydomonas reinhardtii.
Related ArticlesThylakoid localized bestrophin-like proteins are essential for the CO2 concentrating mechanism of Chlamydomonas reinhardtii. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Mukherjee A, Lau CS, Walker CE, Rai AK, Prejean CI, Yates G, Emrich-Mills T, Lemoine SG, Vinyard DJ, Mackinder LCM, Moroney JV Abstract The green alga Chlamydomonas reinhardtii possesses a CO2 concentrating mechanism (CCM) that helps in successful acclimation to low...
pubmed: "proc natl acad sci ...
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Programming curvilinear paths of flat inflatables.
Related ArticlesProgramming curvilinear paths of flat inflatables. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Siéfert E, Reyssat E, Bico J, Roman B Abstract Inflatable structures offer a path for light deployable structures in medicine, architecture, and aerospace. In this study, we address the challenge of programming the shape of thin sheets of high-stretching modulus cut and sealed along their edges. Internal pressure induces the inflation of...
pubmed: "proc natl acad sci ...
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Two types of magnetic shape-memory effects from twinned microstructure and magneto-structural coupling in Fe1+y Te.
Related ArticlesTwo types of magnetic shape-memory effects from twinned microstructure and magneto-structural coupling in Fe1+y Te. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Rößler S, Koz C, Wang Z, Skourski Y, Doerr M, Kasinathan D, Rosner H, Schmidt M, Schwarz U, Rößler UK, Wirth S Abstract A detailed experimental investigation of Fe1+y Te (y = 0.11, 0.12) using pulsed magnetic fields up to 60 T confirms remarkable magnetic shape-memory (MSM)...
pubmed: "proc natl acad sci ...
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TNFR2 promotes Treg-mediated recovery from neuropathic pain across sexes.
Related ArticlesTNFR2 promotes Treg-mediated recovery from neuropathic pain across sexes. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Fischer R, Sendetski M, Del Rivero T, Martinez GF, Bracchi-Ricard V, Swanson KA, Pruzinsky EK, Delguercio N, Rosalino MJ, Padutsch T, Kontermann RE, Pfizenmaier K, Bethea JR Abstract Tumor necrosis factor receptor 2 (TNFR2) is a transmembrane receptor that is linked to immune modulation and tissue regeneration. Here,...
pubmed: "proc natl acad sci ...
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Epithelial delamination is protective during pharmaceutical-induced enteropathy.
Related ArticlesEpithelial delamination is protective during pharmaceutical-induced enteropathy. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Espenschied ST, Cronan MR, Matty MA, Mueller O, Redinbo MR, Tobin DM, Rawls JF Abstract Intestinal epithelial cell (IEC) shedding is a fundamental response to intestinal damage, yet underlying mechanisms and functions have been difficult to define. Here we model chronic intestinal damage in zebrafish larvae...
pubmed: "proc natl acad sci ...
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Fast contribution to the activation energy of a glass-forming liquid.
Related ArticlesFast contribution to the activation energy of a glass-forming liquid. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Hecksher T, Olsen NB, Dyre JC Abstract This paper presents physical-aging data for the silicone oil tetramethyl-tetraphenyl trisiloxane. The density and the high-frequency plateau shear modulus [Formula: see text] were monitored following temperature jumps starting from fully equilibrated conditions. Both quantities exhibit...
pubmed: "proc natl acad sci ...
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CsBRC1 inhibits axillary bud outgrowth by directly repressing the auxin efflux carrier CsPIN3 in cucumber.
Related ArticlesCsBRC1 inhibits axillary bud outgrowth by directly repressing the auxin efflux carrier CsPIN3 in cucumber. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Shen J, Zhang Y, Ge D, Wang Z, Song W, Gu R, Che G, Cheng Z, Liu R, Zhang X Abstract Shoot branching is an important agronomic trait that directly determines plant architecture and affects crop productivity. To promote crop yield and quality, axillary branches need to be manually removed...
pubmed: "proc natl acad sci ...
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Melanin-dot-mediated delivery of metallacycle for NIR-II/photoacoustic dual-modal imaging-guided chemo-photothermal synergistic therapy.
Related ArticlesMelanin-dot-mediated delivery of metallacycle for NIR-II/photoacoustic dual-modal imaging-guided chemo-photothermal synergistic therapy. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Sun Y, Ding F, Chen Z, Zhang R, Li C, Xu Y, Zhang Y, Ni R, Li X, Yang G, Sun Y, Stang PJ Abstract Discrete Pt(II) metallacycles have potential applications in biomedicine. Herein, we engineered a dual-modal imaging and chemo-photothermal therapeutic nano-agent...
pubmed: "proc natl acad sci ...
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Dichotomy of the photo-induced 2-dimensional electron gas on SrTiO3 surface terminations.
Related ArticlesDichotomy of the photo-induced 2-dimensional electron gas on SrTiO3 surface terminations. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Rebec SN, Jia T, Sohail HM, Hashimoto M, Lu D, Shen ZX, Moore RG Abstract Oxide materials are important candidates for the next generation of electronics due to a wide array of desired properties, which they can exhibit alone or when combined with other materials. While SrTiO3 (STO) is often considered...
pubmed: "proc natl acad sci ...
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An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity.
Related ArticlesAn influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Schmidt N, Domingues P, Golebiowski F, Patzina C, Tatham MH, Hay RT, Hale BG Abstract Dynamic small ubiquitin-like modifier (SUMO) linkages to diverse cellular protein groups are critical to orchestrate resolution of stresses such as genome damage, hypoxia, or proteotoxicity....
pubmed: "proc natl acad sci ...
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A general framework for quantitatively assessing ecological stochasticity.
Related ArticlesA general framework for quantitatively assessing ecological stochasticity. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Ning D, Deng Y, Tiedje JM, Zhou J Abstract Understanding the community assembly mechanisms controlling biodiversity patterns is a central issue in ecology. Although it is generally accepted that both deterministic and stochastic processes play important roles in community assembly, quantifying their relative importance...
pubmed: "proc natl acad sci ...
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A small number of cholinergic neurons mediate hyperaggression in female Drosophila.
Related ArticlesA small number of cholinergic neurons mediate hyperaggression in female Drosophila. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Palavicino-Maggio CB, Chan YB, McKellar C, Kravitz EA Abstract In the Drosophila model of aggression, males and females fight in same-sex pairings, but a wide disparity exists in the levels of aggression displayed by the 2 sexes. A screen of Drosophila Flylight Gal4 lines by driving expression of the gene...
pubmed: "proc natl acad sci ...
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DNA probes that store mechanical information reveal transient piconewton forces applied by T cells.
Related ArticlesDNA probes that store mechanical information reveal transient piconewton forces applied by T cells. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Ma R, Kellner AV, Ma VP, Su H, Deal BR, Brockman JM, Salaita K Abstract The advent of molecular tension probes for real-time mapping of piconewton forces in living systems has had a major impact on mechanobiology. For example, DNA-based tension probes have revealed roles for mechanics in...
pubmed: "proc natl acad sci ...
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Five-coordinate MnIV intermediate in the activation of nature's water splitting cofactor.
Related ArticlesFive-coordinate MnIV intermediate in the activation of nature's water splitting cofactor. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Chrysina M, Heyno E, Kutin Y, Reus M, Nilsson H, Nowaczyk MM, DeBeer S, Neese F, Messinger J, Lubitz W, Cox N Abstract Nature's water splitting cofactor passes through a series of catalytic intermediates (S0-S4) before O-O bond formation and O2 release. In the second last transition (S2 to S3) cofactor...
pubmed: "proc natl acad sci ...
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Unknown actor in adipose tissue metabolism hiding in plain sight.
Related ArticlesUnknown actor in adipose tissue metabolism hiding in plain sight. Proc Natl Acad Sci U S A. 2019 Aug 07;: Authors: Collins S PMID: 31391298 [PubMed - as supplied by publisher]
pubmed: "proc natl acad sci ...
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