Πέμπτη 26 Μαρτίου 2020

Antibacterial efficacy of chitosan- and poly(hexamethylene biguanide)-immobilized nanofiber membrane
Publication date: 1 July 2020Source: International Journal of Biological Macromolecules, Volume 154Author(s): I-Son Ng, Chien Wei Ooi, Bing-Lan Liu, Chun-To Peng, Chen-Yaw Chiu, Yu-Kaung Chang
ScienceDirect Publication: International Journal of Biological Macromolecules
16h
Modulating cationicity of chitosan hydrogel to prevent hypertrophic scar formation during wound healing
Publication date: 1 July 2020Source: International Journal of Biological Macromolecules, Volume 154Author(s): Nihui Zhang, Tao Gao, Yao Wang, Juan Liu, Junwei Zhang, Ruijuan Yao, Fang Wu
ScienceDirect Publication: International Journal of Biological Macromolecules
16h
Structural characterization of pectin-bismuth complexes and their aggregation in acidic conditions
Publication date: 1 July 2020Source: International Journal of Biological Macromolecules, Volume 154Author(s): Wen-xin Jiang, Jun-Ru Qi, Jin-song Liao, Zhi-li Wan, Wan-ling Liang, Jia-yi Huang, Yong Cao, Jie Xiao, Xiao-Quan Yang
ScienceDirect Publication: International Journal of Biological Macromolecules
16h
Tensile properties of synthetic pyriform spider silk fibers depend on the number of repetitive units as well as the presence of N- and C-terminal domains
Publication date: 1 July 2020Source: International Journal of Biological Macromolecules, Volume 154Author(s): Hongnian Zhu, Anna Rising, Jan Johansson, Xiaohua Zhang, Ying Lin, Lei Zhang, Tuo Yi, Junpeng Mi, Qing Meng
ScienceDirect Publication: International Journal of Biological Macromolecules
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Evaluation of structure transformation and biocompatibility of chitosan in alkali/urea dissolution system for its large-scale application
Publication date: 1 July 2020Source: International Journal of Biological Macromolecules, Volume 154Author(s): Shichao Bi, Mengyang Wang, Liang Huang, Di Qin, Xiaojie Cheng, Xiguang Chen
ScienceDirect Publication: International Journal of Biological Macromolecules
1d
Determination of glucose generation rate from various types of glycemic carbohydrates by mammalian glucosidases anchored in the small intestinal tissue
Publication date: 1 July 2020Source: International Journal of Biological Macromolecules, Volume 154Author(s): Jung-Min Seo, Lisa M. Lamothe, Hansol Shin, Sean Austin, Sang-Ho Yoo, Byung-Hoo Lee
ScienceDirect Publication: International Journal of Biological Macromolecules
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Microwave assisted synthesis of karaya gum based montmorillonite nanocomposite: Characterisation, swelling and dye adsorption studies
Publication date: 1 July 2020Source: International Journal of Biological Macromolecules, Volume 154Author(s): Bidarakatte Krishnappa Preetha, Badalamoole Vishalakshi
ScienceDirect Publication: International Journal of Biological Macromolecules
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Supermolecular film crosslinked by polyoxometalate and chitosan with superior antimicrobial effect
Publication date: 1 July 2020Source: International Journal of Biological Macromolecules, Volume 154Author(s): Yan Fang, Cuili Xing, Jing Liu, Yahong Zhang, Mingxue Li, Qiuxia Han
ScienceDirect Publication: International Journal of Biological Macromolecules
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Greener production of microcrystalline cellulose (MCC) from <em>Saccharum spontaneum</em> (Kans grass): Statistical optimization
Publication date: 1 July 2020Source: International Journal of Biological Macromolecules, Volume 154Author(s): Julie Baruah, Ramesh Chandra Deka, Eeshan Kalita
ScienceDirect Publication: International Journal of Biological Macromolecules
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Chitosan-based delivery systems for plants: A brief overview of recent advances and future directions
Publication date: 1 July 2020Source: International Journal of Biological Macromolecules, Volume 154Author(s): Muhammad Mujtaba, Khalid Mahmood Khawar, Marcela Candido Camara, Lucas Bragança Carvalho, Leonardo Fernandes Fraceto, Rania E. Morsi, Maher Z. Elsabee, Murat Kaya, Jalel Labidi, Hidayat Ullah, Depeng Wang
ScienceDirect Publication: International Journal of Biological Macromolecules
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Chitosan, <em>N</em>,<em>N</em>,<em>N</em>-trimethyl chitosan (TMC) and 2-hydroxypropyltrimethyl ammonium chloride chitosan (HTCC): The potential immune adjuvants and nano carriers
Publication date: 1 July 2020Source: International Journal of Biological Macromolecules, Volume 154Author(s): Jing Zhao, Jinqi Li, Zhongliang Jiang, Rongsheng Tong, Xingmei Duan, Lan Bai, Jianyou Shi
ScienceDirect Publication: International Journal of Biological Macromolecules
1d
Utilizing Digital Health to Collect Electronic Patient-Reported Outcomes in Prostate Cancer: Single-Arm Pilot Trial
*Journal* of *Medical Internet Research*
16h
The Association of Therapeutic Alliance With Long-Term Outcome in a Guided Internet Intervention for Depression: Secondary Analysis From a Randomized Control Trial
*Journal* of *Medical Internet Research*
1d
Hackathons as Stepping Stones in Health Care Innovation: Case Study With Systematic Recommendations
*Journal* of *Medical Internet Research*
1d
Measuring Alliance Toward Embodied Virtual Therapists in the Era of Automated Treatments With the Virtual Therapist Alliance Scale (VTAS): Development and Psychometric Evaluation
*Journal* of *Medical Internet Research*
1d
An Asynchronous Curriculum for Teaching Practical Interpretation Skills of Clinical Images to Residents in Emergency Medicine
Publication date: Available online 25 March 2020Source: The Journal of Emergency MedicineAuthor(s): Anne M. Messman, Adrienne Malik, Robert Ehrman
ScienceDirect Publication: The Journal of Emergency Medicine
16h
Use of High-Flow Nasal Cannula for Immunocompromise and Acute Respiratory Failure: A Systematic Review and Meta-Analysis
Publication date: Available online 24 March 2020Source: The Journal of Emergency MedicineAuthor(s): Yiwei Wang, Yuenan Ni, Jikui Sun, Zongan Liang
ScienceDirect Publication: The Journal of Emergency Medicine
16h
Percutaneous Thrombectomy in Emergency Department Patients with Pulmonary Embolism: The FLARE ED Sub-study
Publication date: Available online 24 March 2020Source: The Journal of Emergency MedicineAuthor(s): Wissam A. Jaber, Christopher Kabrhel, Kenneth Rosenfield, Thomas Tu, Kenneth Ouriel, Victor F. Tapson
ScienceDirect Publication: The Journal of Emergency Medicine
16h
Should Antiemetics be Given Prophylactically with Intravenous Opioids While Treating Acute Pain in the Emergency Department?: Clinical Practice Paper Approved by American Academy of Emergency Medicine Clinical Guidelines Committee
Publication date: Available online 23 March 2020Source: The Journal of Emergency MedicineAuthor(s): Kristin D. Rowland, Justin Fuehrer, Sergey M. Motov, Gary Vilke, Steven B. Rosenbaum, Faith Quenzer
ScienceDirect Publication: The Journal of Emergency Medicine
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Emergency Endotracheal Intubation With a Rigid Stylet of an Infant With Severe Subglottic Stenosis
Publication date: Available online 23 March 2020Source: The Journal of Emergency MedicineAuthor(s): Jonathan R. Strutt, Nicole R. Thompson, Jennifer L. Stotesbery, Balazs Horvath
ScienceDirect Publication: The Journal of Emergency Medicine
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Bimodal Strategy for Excellent Audiological Rehabilitation in a Subject with a Novel Nonsense Mutation of the <em>SLC26A4</em> Gene: a Case Report
Publication date: Available online 24 March 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Rita Malesci, Roberta Russo, Carmela Monzillo, Carla Laria, Virginia Corvino, Gennaro Auletta, Achille Iolascon, Annamaria Franzè
ScienceDirect Publication: International Journal of Pediatric Otorhinolaryngology
16h
Audiologic Testing in Children with Down Syndrome: Are Current Guidelines Optimal?
Publication date: Available online 24 March 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Razan A. Basonbul, Evette A. Ronner, Anni Rong, Gina Rong, Michael S. Cohen
ScienceDirect Publication: International Journal of Pediatric Otorhinolaryngology
16h
Primary Tracheocutaneous Fistula Closure with Immediate Transition to Nocturnal Noninvasive Positive Pressure Ventilation in Two Children with Congenital Central Hypoventilation Syndrome
Publication date: Available online 24 March 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Samantha L. Kallenbach, Mana Espahbodi, Louella B. Amos, David J. Beste, Robert H. Chun
ScienceDirect Publication: International Journal of Pediatric Otorhinolaryngology
1d
A Rare Case of Gastric Schwannoma: A Case Report and Literature Review
In general, schwannoma is a benign and slow-glowing neoplasm that rarely occurs in the gastrointestinal tract as a submucosal tumor (SMT), with the most common site being the stomach. As gastric schwannoma (GS) is a rare tumor, there is limited data in the literature about its clinical features. The diagnosis of schwannoma can only be made by pathological examination with positive staining for S-100 protein. It is necessary to obtain an accurate diagnosis to introduce optimal treatment options preoperatively....
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Cinacalcet for the Treatment of Humoral Hypercalcemia of Malignancy: An Introductory Case Report with a Pathophysiologic and Therapeutic Review
Hypercalcemia is an ominous development in the course of malignancy associated with a mean survival of only several months. A majority of cases of hypercalcemia are related to humoral hypercalcemia of malignancy (HHM), where hypercalcemia is caused by increased levels of circulating parathyroid hormone-related protein (PTHrP). Mainstay treatments in the management of HHM are intravenous fluids, intravenous bisphosphonates, and subcutaneous denosumab, although hypercalcemia oftentimes recurs despite...
CRO : Last 20 articles
16h
Chronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab – Diagnostic and Therapeutic Challenge: A Case Report
Due to the widespread use of immune checkpoint inhibitors and the growing research efforts in this area, immune-mediated toxicity is well recognized. Nonetheless, few severe cases of oral or upper gastrointestinal tract mucosal involvement have been documented. Early recognition and prompt treatment are key to the adequate management of these patients. We present a male 93-year-old patient with an advanced head and neck tumor treated with nivolumab who developed severe oral ulcers. After discontinuation...
CRO : Last 20 articles
19h
A Case of Diffuse Large B Cell Lymphoma of the Breast with Predominantly High-Level Internal Echoes
A 70-year-old woman had a large mass in her right breast. Mammography displayed focal asymmetrical density in the scattered areas of fibroglandular density. Ultrasonography showed the tumor to have predominantly high-level internal echoes. Histological examination showed that the tumor was composed of CD20-positive atypical cells with a large nucleus, scant cytoplasm, and abundant mitoses accompanied by a lot of fat cell interspersion and the diagnosis of diffuse large B cell lymphoma was made. We...
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Grade 3 Hepatotoxicity following Fulvestrant, Palbociclib, and Erdafitinib Therapy in a Patient with ER-Positive/PR-Negative/HER2-Negative Metastatic Breast Cancer: A Case Report
A 49-year-old woman with ER-positive/PR-negative/HER2-negative metastatic breast cancer experienced Grade 3 hepatotoxicity following initiation of a clinical trial of fulvestrant, palbociclib, and erdafitinib. Fulvestrant was determined to be the drug most likely responsible for this hepatotoxic effect. This case report details the timing and nature of this drug-induced liver injury, adding support to an area that has yet to be described adequately in the existing literature.Case Rep Oncol 2020;13:304–308
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Therapy-Related Acute Myeloid Leukemia 2 Months after Chemoradiotherapy for Esophageal Cancer: A Case Report
Therapy-related acute myeloid leukemia (AML) is a rare but potentially fatal adverse event caused by chemotherapy or radiotherapy. Herein we report a patient diagnosed with therapy-related AML 2 months after chemoradiotherapy for esophageal cancer. A 61-year-old man with dysphagia was diagnosed with locally advanced esophageal cancer with para-aortic lymph node metastasis. Laboratory blood test did not reveal any abnormality except mild macrocytic anemia. To alleviate dysphagia due to malignant esophageal...
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Graves’ Disease-Related Pancytopenia Improved after Radioactive Iodine Ablation
Graves’ disease is an autoimmune disease that affects the thyroid glands which often results in enlarged thyroid glands, and it is the most common cause of clinical hyperthyroidism especially in young patients. Radioiodine ablation is a radiation therapy in which radioactive iodine is administered to destroy or ablate thyroid cells. It is commonly used for the treatment of Graves’ disease. We report on a 39-year-old male, who presented with Graves’ disease, found to have pancytopenia and hypocellular...
CRO : Last 20 articles
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Outcome of Pregnancy in the Era of PEGylated Interferon-α2a in Females with Chronic Myeloid Leukemia: An Experience from Qatar
Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia, is a myeloproliferative neoplasm characterized by increased proliferation of the granulocytic cell line without loss of its capacity to differentiate. It accounts for 20% of all adults affected by leukemia. Tyrosine kinase inhibitors revolutionized the treatment for CML and improved quality of life. Fertility is an important issue for both males and females. Here, we report our experience with a pregnant female with CML,...
CRO : Last 20 articles
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Transcatheter Arterial Chemoembolization Treatment for Vulvar Cancer: A Case Report
Vulvar cancer is a rare malignant tumor occurring in elderly postmenopausal women. At present, surgery is the main treatment for vulvar cancer. Chemotherapy alone has no obvious therapeutic effect as a treatment for vulvar cancer, so it is often combined with radiotherapy or surgery. Selective arterial infusion chemotherapy and embolization is rarely used for the treatment of vulvar cancer. A 63-year-old Tibetan woman underwent superselective arteriography and embolization. On the 7th day after the...
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Serotonin Syndrome Developing Immediately after the Initiation of Low-Dose Methadone Therapy: A Case Report
We present a case in which serotonin syndrome developed immediately after the initiation of low-dose methadone following an increase in oxycodone dose and the initiation of duloxetine. The symptoms of serotonin syndrome were alleviated and later disappeared upon cessation of methadone alone. The case was a 47-year-old woman with a desmoid tumor. The administration of duloxetine (20 mg/day) was initiated while the patient took oxycodone sustained-release tablets (40 mg/day). The following day, excessive...
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Primary Bone Lymphoma in Axial Skeleton in a Middle-Aged Female Presented as Recurrent Anemia
Primary bone lymphoma (PBL) is a peculiar extranodal presentation of non-Hodgkin’s lymphoma. Primary bone diffuse large B-cell lymphoma (DLBCL) is the most common pathological type, comprising about 80% of PBL. The diagnosis of PBL depends on the combined clinical examination and imaging studies and is confirmed with immunohistochemical examination. Due to the rarity of this disease, more relative studies and case reports are needed to provide insight into this obscure lymphoproliferative malignancy....
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Successful Treatment of a Patient with anti-PD1 Antibody-Resistant Advanced Mucosal Melanoma with Nivolumab, Ipilimumab plus Denosumab Combination Therapy
Since the incidence of mucosal melanoma is higher in the Japanese population compared to Caucasians, and since mucosal melanoma possesses a lower mutation burden compared to cutaneous melanoma, the efficacy of anti-PD1 antibody (Ab) monotherapy for mucosal melanoma is limited. Therefore, other targeting molecules that enhance the anti-tumor effects of immune checkpoint inhibitors are needed. In this report, we present a case with anti-PD1 Ab-resistant recurrent malignant melanoma of the nasal cavity...
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Mutations within the Activation Loop Domain of FLT3 in Two Pediatric Patients with Refractory Infant Acute Myeloid Leukemia
Approximately 24% of all pediatric acute myeloid leukemia (AML) cases have mutations in the FMS-like tyrosine kinase 3 (FLT3) receptor gene. FLT3-TKD point mutations are rare in pediatrics and often occur in younger patients and in combination with 11q23 abnormalities. There is a paucity of data related to their prognostic implications in children. We describe 2 pediatric patients with FLT3-activating mutations as a feature of their AML. Both were diagnosed in infancy. The first experienced induction...
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A Case of Locally Advanced Breast Cancer Successfully Treated with Multidisciplinary Therapy
A 42-year-old woman with locally advanced luminal breast cancer was referred to our hospital. Ultrasonography showed marked skin thickening with obscured breast mass. Positron emission tomography showed bilateral swelling in the axillar, parasternal, and supraclavicular lymph nodes in addition to the primary breast cancer. Following the patient’s request, we treated her with primary bevacizumab-containing chemotherapy followed by radiotherapy to the breast due to the histologically proven widely...
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Surgical Treatment of Sacral Chordoma: The Role of Laparoscopy
Sacral chordoma is a rare tumour that represents the most common malignancy of the sacral region. Its diagnosis can be delayed because of unclear clinical manifestation. This tumour can involve surrounding anatomical structure such as the rectum, and its surgical treatment is still challenging. We report on 3 patients with sacral chordoma. Two of them were successfully treated using a laparoscopic approach and one by open surgery. We present all details of the surgical technique and patients’ outcome....
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Pazopanib after Nivolumab-Induced Tumor Lysis Syndrome in a Patient with Metastatic Clear-Cell Renal Cell Carcinoma
Nivolumab, a programmed death-1 checkpoint inhibitor, is worldwide available for metastatic renal cell carcinoma (mRCC). Limited data exist on the response to vascular endothelial growth factor receptor-tyrosine kinase inhibitor (TKI) therapy after administration of nivolu­mab. In this case study, we report on a patient with tumor lysis syndrome (TLS), which was induced by pazopanib after the administration of nivolumab. A 69-year-old woman with a primary diagnosis of mRCC received pazopanib as a...
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