Τετάρτη 25 Μαρτίου 2020


Nurses intuitive worrying predicts physiological changes in patients vital signs
Commentary on: Romero-Brufau S, Gaines K, Nicolas CT, et al. The fifth vital sign? Nurse worry predicts inpatient deterioration within 24 hours. JAMIA Open 2019.Implications for practice and researchWorry factor scores may assist nurses with assessment and prediction of patient deterioration in hospitals.Further research is needed to determine the weight of the worry factor variable in conjunction with other elements of early warning score systems.ContextThe introduction of early warning scores and...
Evidence-Based Nursing Online First
2h
Without adequate nursing support for families, dying at home threatens the values of a good death
Commentary on: Hoare S, Kelly MP, Barclay S. Home care and end-of-life hospital admissions: a retrospective interview study in English primary and secondary care. Br J Gen Pract 2019;69(685):E561–9.Implications for practice and researchFamilies providing end-of-life care in the home urgently require well-resourced community nursing services.Future research should explore the perspectives of people who choose, for whatever reason, not to take on formal and intimate caregiving roles for their dying...
Evidence-Based Nursing Online First
2h
Delirium occurrence in hospitalised older people is positively associated with development of dementia postdischarge
Commentary on: Garcez FB, Apolinario D, Campora F et al. Delirium and post-discharge dementia: results from a cohort of older adults without baseline cognitive impairment. Age Ageing 2019;48:845–51.Implications for practice and researchAs many as one in three older people who experience delirium in a hospital setting may go on to develop dementia.Delirium is associated with longer term cognitive impairment but there has been limited research or evidence about its impact on older people.Future research...
Evidence-Based Nursing Online First
14h
Lack of education and co-ordination of care are main factors affecting palliative care provision by primary care practitioners
Commentary on: Carey ML, Zucca AC, Freund MA, et al. Systematic review of barriers and enablers to the delivery of palliative care by primary care practitioners. Palliat Med 2019;33:1131–45.Implications for practice and researchPrimary care service providers should consider improving education, interprofessional communication and re-organising care pathways by minimising bureaucratic processes, in order to provide quality, holistic palliative care services.Future research should focus on understanding...
Evidence-Based Nursing Online First
14h
Telemedicine for Age-Related Macular Degeneration
Telemedicine and e-Health, Ahead of Print.
Telemedicine and e-Health - Table of Contents
2h
Telemedicine for Retinopathy of Prematurity
Telemedicine and e-Health, Ahead of Print.
Telemedicine and e-Health - Table of Contents
2h
Telemedicine for Glaucoma: Guidelines and Recommendations
Telemedicine and e-Health, Ahead of Print.
Telemedicine and e-Health - Table of Contents
12h
Practice Guidelines for Ocular Telehealth-Diabetic Retinopathy, Third Edition
Telemedicine and e-Health, Ahead of Print.
Telemedicine and e-Health - Table of Contents
12h
Automated and Computer-Assisted Detection, Classification, and Diagnosis of Diabetic Retinopathy
Telemedicine and e-Health, Ahead of Print.
Telemedicine and e-Health - Table of Contents
12h
The Role of e-Health in the Delivery of Care for Patients with Hematological Cancers: A Systematic Literature Review
Telemedicine and e-Health, Ahead of Print.
Telemedicine and e-Health - Table of Contents
1d
Reduction of early inpatient transfers and rapid response team calls after implementation of an emergency department intake huddle process
Patients admitted to the hospital and requiring a subsequent transfer to a higher level of care have increased morbidity, mortality and length of stay compared with patients who do not require a transfer during their hospital stay. We identified that a high number of patients admitted to our intermediate care (IMC) unit required a rapid response team (RRT) call and an early (<24 hours) transfer to the intensive care unit (ICU). A quality improvement project was initiated with the goal to reduce...
BMJ QIR Current Issue
2h
Testicular cancer: improving outcomes with national quality performance indicators
Testicular cancer is the most common malignancy in young adult men. The prognosis is excellent in limited disease and cure is possible even in advanced disease. Quality performance indicators (QPI) are used in many developed countries as a measure of healthcare performance. We report and discuss the development of a national set of QPIs in Scotland for testicular cancer as a method of gathering demographic data and driving improvement in nationwide testicular cancer outcomes.
BMJ QIR Current Issue
23h
Improving the documentation quality of point-of-care ultrasound scans in the emergency department
A point-of-care ultrasound scan (POCUS) is a core element of the Royal College of Emergency Medicine (RCEM) specialty training curriculum. However, POCUS documentation quality can be poor, especially in the time-pressured environment of the emergency department (ED). A survey of 10 junior ED clinicians at the Princess Royal University Hospital (PRUH) found that total POCUS documentation was as low as 38% in some examinations. This quality improvement project aimed to increase the coverage and quality...
BMJ QIR Current Issue
23h
Community-based prehabilitation before elective major surgery: the PREP-WELL quality improvement project
Optimising health and well-being before elective major surgery via prehabilitation initiatives is important for good postoperative outcomes. In a busy tertiary centre in North East England, the lack of a formal prehabilitation service meant that opportunities were being missed to optimise patients for surgery. This quality improvement project aimed to implement and evaluate a community-based prehabilitation service for people awaiting elective major surgery: PREP-WELL. A multidisciplinary, cross-sector...
BMJ QIR Current Issue
23h
Improving blood pressure screening and control at an academic health system
The goal of the University of California Davis Health Blood Pressure (BP) Quality Improvement Initiative was to improve the diagnosis, management and control of high BP. Patients aged 18–85 years were included in the initiative. Lean A3 problem solving was used to implement the following evidence-based interventions based on stakeholder interviews, value stream mapping and the Centers for Disease Control and Prevention’s Million Hearts Initiative: staff training on accurate BP measurement, visual...
BMJ QIR Current Issue
23h
Impact of an interdisciplinary malnutrition quality improvement project at a large metropolitan hospital
As many as 50% of hospitalised patients are estimated to be malnourished or at risk of malnutrition on hospital admission, but this condition often goes unrecognised, undiagnosed and untreated. Malnutrition is associated with an elevated need for continued medical interventions, higher costs of care and increased patient safety risks. Tampa General Hospital (TGH), a large teaching hospital in the southeastern USA, initiated a project to improve the quality of patient care at its institution. They...
BMJ QIR Current Issue
1d
Accuracy of medical billing data against the electronic health record in the measurement of colorectal cancer screening rates
ObjectiveMedical billing data are an attractive source of secondary analysis because of their ease of use and potential to answer population-health questions with statistical power. Although these datasets have known susceptibilities to biases, the degree to which they can distort the assessment of quality measures such as colorectal cancer screening rates are not widely appreciated, nor are their causes and possible solutions. MethodsUsing a billing code database derived from our institution’s...
BMJ QIR Current Issue
1d
Development and application of 'systems thinking principles for quality improvement
Introduction‘Systems thinking’ is often recommended in healthcare to support quality and safety activities but a shared understanding of this concept and purposeful guidance on its application are limited. Healthcare systems have been described as complex where human adaptation to localised circumstances is often necessary to achieve success. Principles for managing and improving system safety developed by the European Organisation for the Safety of Air Navigation (EUROCONTROL; a European intergovernmental...
BMJ QIR Current Issue
1d
Closing the gap: actualising shared decision-making through effective medication abortion patient follow-up care
BackgroundEffective care dearth in USA healthcare systems can be augmented by patient engagement and shared decision-making (SDM). These effective care strategies can facilitate medical abortion follow-up care (ensuring patients are not experiencing a continuing pregnancy) and follow-up options access. Local problemThe quality improvement project clinic had a state-mandated waiting period, requiring additional visits. This delayed care for all abortion patients, creating travel, and cost barriers....
BMJ QIR Current Issue
1d
Primary cardiac undifferentiated pleomorphic sarcoma: an alarming cause of lower back pain
BMJ Case Reports Last 6 Issues
4h
Boundaries of a systemic disease: a protean presentation of giant cell arteritis
A 60-year-old man was hospitalised with persistent fever, arm pain, dry cough and cholestasis. Diagnostic workup was remarkable for elevated inflammatory markers. Infectious diseases and autoimmune screening were negative. Imaging modalities excluded a neoplastic aetiology. Liver biopsy was negative for granulomatous or lymphomatous infiltrations. Giant cell arteritis (GCA) was suspected, but temporal artery Doppler ultrasound and biopsy were non-diagnostic. A positron emission tomography scan showed...
BMJ Case Reports Last 6 Issues
4h
ROS1-rearranged lung adenocarcinoma with peritoneal carcinomatosis on initial presentation
Peritoneal carcinomatosis (PC) is progression of the primary cancer to the peritoneum that is seen in only 1.2% of patients with lung cancer. It is associated with poor prognosis especially if present at the time of initial cancer diagnosis. The predisposing factors for peritoneal spread are not yet well understood. It has been suggested that the oncogene status of the tumour can influence the patterns of metastatic spread. There is not enough data about the role of c-ROS oncogene 1 (ROS1) mutation...
BMJ Case Reports Last 6 Issues
4h
Pulmonary hyalinising granuloma: a rare and elusive cause of multiple lung nodules
A 72-year-old woman was referred with incidentally detected multiple lung nodules, one of which was identified as 18F-fluorodeoxyglucose (FDG)-avid on positron emission tomography. Extensive workup followed, including numerous radiographs, surveillance scans and a CT-guided biopsy which demonstrated chronic inflammation only. Following a wedge-resection, a diagnosis of pulmonary hyalinising granuloma (PHG) was made. PHG is a cause of FDG-avid single or multiple pulmonary nodules and can mimic lung...
BMJ Case Reports Last 6 Issues
4h
Adenocarcinoma of an ileal conduit developing 8 years after cystoprostatectomy for locally advanced prostate carcinoma
A 70-year-old patient was treated in September 2017 for a malignancy in an ileal conduit (IC) which he received in 2009 for the treatment of prostate cancer. The tumour was found incidentally during a routine sonography. A CT scan revealed a mass near the IC. An endoscopy with biopsies showed an intraepithelial neoplasia of the ileal mucosa in the IC. We performed a segmental ileal resection. Histological findings revealed an ileal adenocarcinoma. The postoperative course was uneventful. The patient...
BMJ Case Reports Last 6 Issues
15h
Broncho-oesophageal fistula after lung cancer treatment
BMJ Case Reports Last 6 Issues
15h
Preventive measures to avoid vertical transmission in untreated pregnant women with HIV/AIDS
The HIV/AIDS during pregnancy has high morbidity and mortality, without optimal prevention and treatment. The advanced stage cases are found in developing countries due to late detection, but, also in developed countries due to immigration; therefore, the professionals should know the management steps for these patients. The implementation of specific interventions can reduce vertical transmission incidence until 1%–8%. It is presented a case of a pregnant woman with AIDS detected during first hospitalisation,...
BMJ Case Reports Last 6 Issues
15h
Transitioning a patient from injectable opioid agonist therapy to sublingual buprenorphine/naloxone for the treatment of opioid use disorder using a microdosing approach
In the wake of North America’s opioid crisis, access to evidence-based treatment for opioid use disorder (OUD) is of critical importance. While buprenorphine/naloxone and methadone are currently indicated as first-line medications for the treatment of OUD, there are a proportion of individuals who do not benefit from these therapies. Recent Canadian guidelines suggest the use of alternate therapies, including slow-release oral morphine or injectable opioid agonist therapy (iOAT) for individuals unsuccessful...
BMJ Case Reports Last 6 Issues
15h
Eagle syndrome: elongated stylohyoid-associated facial pain
BMJ Case Reports Last 6 Issues
1d
Subacute combined degeneration: a case of pernicious anaemia without haematological manifestations
Vitamin B12 deficiency can be caused by a diverse group of aetiologies. One of the less common of these is an autoimmune condition pernicious anaemia, so named after the most common physiological manifestation of B12 deficiency: anaemia. However, B12 is also necessary for nervous system function and its depletion can lead to dysfunction of the posterior columns of the spinal cord resulting in subacute combined degeneration (SCD). This disease, while debilitating in its acute phase, can usually be...
BMJ Case Reports Last 6 Issues
1d
Fibromuscular dysplasia and coronary artery fistula: links to pulmonary hypertension
BMJ Case Reports Last 6 Issues
1d
Retrograde jejunogastric intussusception presenting as haematemesis in a patient following pancreaticoduodenectomy
Intussusception is defined as the invagination of one part of the gastrointestinal tract into another. Jejunogastric intussusception is a rare phenomenon following major upper abdominal surgery, where its aetiology is not well understood. We describe a 68-year-old woman who presented with abdominal pain and haematemesis on the background of a previous pancreaticoduodenectomy (Whipple procedure) for pancreatic cancer. Gastroscopy demonstrated retrograde jejunogastric intussusception, where part of...
BMJ Case Reports Last 6 Issues
1d
PSMA-PET/CT-avid metastatic prostate cancer to the penis
Penile metastases from prostate cancer (PC) are rarely reported in the literature. Most commonly diagnosed due to presentation with malignant priapism and other urinary symptoms or from findings on clinical examination, prognosis has been reported to be poor. The authors outline a case of penile metastasis from advanced PC. Initially treated with neoadjuvant androgen deprivation therapy for locally advanced PC, this patient displayed upfront castrate resistance, and subsequent prostate-specific membrane...
BMJ Case Reports Last 6 Issues
1d
Inherited cause of in utero digital malformations
Amniotic band sequence (ABS) is common birth defect of incompletely understood origin. Here we describe a case of ABS in a child with paternally inherited Ehlers-Danlos syndrome, vascular type (vEDS). This is the third reported instance of ABS associated with paternally inherited vEDS in the medical literature. The two main theories of ABS formation are the extrinsic and intrinsic. The extrinsic theory states that placental tears form fibrous cords that wrap around the fetus; the intrinsic states...
BMJ Case Reports Last 6 Issues
1d
Syndrome of inappropriate antidiuretic hormone associated with eosinophilic granulomatosis and polyangiitis
A 62-year-old man presented with classic signs and symptoms of eosinophilic granulomatosis and polyangiitis (EGPA, also known as Churg-Strauss syndrome)—mononeuritis multiplex, palpable purpura, hypereosinophilia, positive P-ANCA (perinuclear anti-neutrophil cytoplasmic antibodies) developed diffuse alveolar haemorrhage. The patient had longstanding mild hyponatraemia, but developed moderate and symptomatic hyponatraemia characteristic of the syndrome of inappropriate antidiuretic hormone. The patient’s...
BMJ Case Reports Last 6 Issues
1d
Synchronous metaplastic breast carcinoma and lung adenocarcinoma: a rare case and review of the literature
Synchronous primary cancers occur in 1.7% of breast cancer cases and metaplastic breast cancer (MBC) occurs in less than 1% of breast cancer cases. We present a previously healthy 66-year-old woman diagnosed with MBC after surgical resection of a presumed cyst. A second primary cancer, multifocal lung adenocarcinoma, was discovered during the staging process for her MBC. Remarkably she had not experienced pulmonary or constitutional symptoms at the time of diagnosis. She received chemotherapy with...
BMJ Case Reports Last 6 Issues
1d
Bleb-related tuberculous endophthalmitis following combined phacoemulsification and trabeculectomy with mitomycin C
A one-eyed 67-year-old man with 20/400 vision, dense cataract, previously failed trabeculectomy and medically uncontrolled advanced glaucoma underwent a single-site phacoemulsification with repeat trabeculectomy and mitomycin C. One-week postoperatively, vision in the right eye improved to 20/120, good bleb and intraocular pressure (IOP) of 14 mm Hg. By third postoperative week, patient presented to the emergency with diminished vision, pain and redness in right eye of 2 days duration and was diagnosed...
BMJ Case Reports Last 6 Issues
1d
Translation and cultural adaptation of a prostate cancer screening decision aid: a qualitative study in Portugal
ObjectivesTo translate and culturally adapt an English language patient decision aid addressing prostate cancer screening, so it can be used by Portuguese men. DesignQualitative study. We followed the European Centre for Disease Prevention and Control’s (ECDC) five-step, stakeholder-based approach to adapting health communication materials: (1) selection of materials and process coordinators, (2) early review, (3) translation and back translation, (4) comprehension testing with cognitive semi-structured...
BMJ Open Current Issue
4h
Accuracy and consequences of using trial-of-antibiotics for TB diagnosis (ACT-TB study): protocol for a randomised controlled clinical trial
IntroductionOver 40% of global tuberculosis case notifications are diagnosed clinically without mycobacteriological confirmation. Standard diagnostic algorithms include ‘trial-of-antibiotics’—empirical antibiotic treatment given to mycobacteriology-negative individuals to treat infectious causes of symptoms other than tuberculosis, as a ‘rule-out’ diagnostic test for tuberculosis. Potentially 26.5 million such antibiotic courses/year are prescribed globally for the 5.3 million/year mycobacteriology-negative...
BMJ Open Current Issue
4h
International mixed methods study protocol to develop a patient-reported outcome measure for all types of chronic wounds (the WOUND-Q)
IntroductionMost patient-reported outcome measures (PROM) for chronic wounds are specific to a single wound type (eg, pressure ulcer) or part of the body. A barrier to outcome assessment in wound care and research is the lack of a rigorously designed PROM that can be used across wound types and locations. This mixed method study describes the protocol for an international collaboration to develop and validate a new PROM called the WOUND-Q for adults with chronic wounds. Methods and analysisIn phase...
BMJ Open Current Issue
4h

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