Nutrients, Vol. 12, Pages 881: Crescent-Like Lesions as an Early Signature of Nephropathy in a Rat Model of Prediabetes Induced by a Hypercaloric Diet Nutrients doi: 10.3390/nu12040881 Authors: Sara Nunes André Alves Inês Preguiça Adelaide Barbosa Pedro Vieira Fernando Mendes Diana Martins Sofia D. Viana Flávio Reis Diabetic nephropathy (DN) is a major microvascular complication of diabetes. Obesity and hyperlipidemia, fueled by unhealthy food habits, are risk...
Wed Mar 25, 2020 02:00
Nutrients, Vol. 12, Pages 886: Evening Meal Types and Family Meal Characteristics: Associations with Demographic Characteristics and Food Intake among Adolescents Nutrients doi: 10.3390/nu12040886 Authors: Overcash Davey Zhang Reicks Evening meal types and family meal characteristics among adolescents may vary by demographic characteristics and weight status and can negatively impact dietary intake. We used cross-sectional Family, Life, Activity, Sun, Health, and Eating...
Wed Mar 25, 2020 02:00
Nutrients, Vol. 12, Pages 883: Effects of Rambutan Peel (Nepheliumlappaceum) PhenolicExtract on RANKL-Induced Differentiation of RAW264.7 Cells into Osteoclasts and Retinoic Acid-Induced Osteoporosis in Rats Nutrients doi: 10.3390/nu12040883 Authors: Yongliang Zhuang Xiaodong Sun Bingtong Liu Hu Hou Yun Sun Previous studies have shown that rambutan peel phenolic (RPP) extract has excellent biological activities due to its abundant phenolic content and profile. In this study,...
Wed Mar 25, 2020 02:00
Nutrients, Vol. 12, Pages 884: Nutritional Content, Labelling and Marketing of Breakfast Cereals on the Belgian Market and Their Reformulation in Anticipation of the Implementation of the Nutri-Score Front-Of-Pack Labelling System Nutrients doi: 10.3390/nu12040884 Authors: Marie Vermote Stephanie Bonnewyn Christophe Matthys Stefanie Vandevijvere Objective: Breakfast cereals are frequently consumed in Belgium, especially among children. We investigated the nutritional content,...
Wed Mar 25, 2020 02:00
Nutrients, Vol. 12, Pages 882: Food Liking-Based Diet Quality Indexes (DQI) Generated by Conceptual and Machine Learning Explained Variability in Cardiometabolic Risk Factors in Young Adults Nutrients doi: 10.3390/nu12040882 Authors: Xu Blanchard McCaffrey Woolley Corso Duffy The overall pattern of a diet (diet quality) is recognized as more important to health and chronic disease risk than single foods or food groups. Indexes of diet quality can be derived theoretically...
Wed Mar 25, 2020 02:00
Nutrients, Vol. 12, Pages 880: A Case-Based Approach to New Directions in Dietary Therapy of Crohn’s Disease: Food for Thought Nutrients doi: 10.3390/nu12030880 Authors: Arie Levine Wael El-Matary Johan Van Limbergen Recent evidence has demonstrated that Crohn’s disease may have its roots in dysbiosis of the microbiome and other environmental factors. One of the strongest risk factors linked to immune activation appears to be diet. Exclusion diets have been shown to ameliorate...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 879: Cytoprotective Effects of Natural Highly Bio-Available Vegetable Derivatives on Human-Derived Retinal Cells Nutrients doi: 10.3390/nu12030879 Authors: Ingrid Munia Laurent Gafray Marie-Agnès Bringer Pablo Goldschmidt Lil Proukhnitzky Nathalie Jacquemot Christine Cercy Khaoula Ramchani Ben Otman Marie Hélène Errera Isabelle Ranchon-Cole Retinal pigment epithelial cells are crucial for retina maintenance, making their cytoprotection...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 878: Relationships between Obesity, Nutrient Supply and Primary Open Angle Glaucoma in Koreans Nutrients doi: 10.3390/nu12030878 Authors: Lee Kim Lee Kim Lee Park To investigate the association between nutrient intake and primary open angle glaucoma (POAG) in Koreans, a population-based, cross-sectional survey, the Korean National Health and Nutrition Examination Survey, was analyzed. Glaucoma diagnosis was based on criteria established...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 876: Effectiveness of Nutrition Interventions in Vending Machines to Encourage the Purchase and Consumption of Healthier Food and Drinks in the University Setting: A Systematic Review Nutrients doi: 10.3390/nu12030876 Authors: Megan C. Whatnall Amanda J. Patterson Melinda J. Hutchesson University food environments typically offer an abundance of unhealthy foods, including through vending machines. This review evaluated the effectiveness of nutrition interventions...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 874: Determinants of Adherence in Time-Restricted Feeding in Older Adults: Lessons from a Pilot Study Nutrients doi: 10.3390/nu12030874 Authors: Stephanie A. Lee Caroline Sypniewski Benjamin A. Bensadon Christian McLaren William T. Donahoo Kimberly T. Sibille Stephen Anton Time-restricted feeding (TRF) is a type of intermittent fasting in which no calories are commonly consumed for approximately 12–18 hours on a daily basis. The health...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 875: Reliable Measures of Sarcopenia in Cirrhosis. Comment on: “The Relationship of Obesity, Nutritional Status and Muscle Wasting in Patients Assessed for Liver Transplantation, Nutrients 2019, 11, 2097” Nutrients doi: 10.3390/nu12030875 Authors: Maryam Ebadi Carlos Moctezuma-Velazquez Rahima A. Bhanji Aldo J. Montano-Loza We read with interest the manuscript by Vidot et al [...]
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 877: Food Agency in the United States: Associations with Cooking Behavior and Dietary Intake Nutrients doi: 10.3390/nu12030877 Authors: Julia A. Wolfson Jacob Lahne Minakshi Raj Noura Insolera Fiona Lavelle Moira Dean “Food agency” is one’s ability to procure and prepare food within the contexts of one’s social, physical, and economic environment. In 2018, we used Amazon TurkPrime to field two large national...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 873: Nutritional Challenges in Pregnant Women with Renal Diseases: Relevance to Fetal Outcomes Nutrients doi: 10.3390/nu12030873 Authors: Pasquale Esposito Giacomo Garibotto Daniela Picciotto Francesca Costigliolo Francesca Viazzi Novella Evelina Conti Pregnancy in women affected by chronic kidney disease (CKD) has become more common in recent years, probably as a consequence of increased CKD prevalence and improvements in the care provided to...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 872: Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review Nutrients doi: 10.3390/nu12030872 Authors: Gaber El-Saber Batiha Amany Magdy Beshbishy Lamiaa G. Wasef Yaser H. A. Elewa Ahmed A. Al-Sagan Mohamed E. Abd El-Hack Ayman E. Taha Yasmina M. Abd-Elhakim Hari Prasad Devkota Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices,...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 870: Diet and Skin Aging—From the Perspective of Food Nutrition Nutrients doi: 10.3390/nu12030870 Authors: Cao Xiao Wu Ge We regularly face primary challenges in deciding what to eat to maintain young and healthy skin, defining a healthy diet and the role of diet in aging. The topic that currently attracts maximum attention is ways to maintain healthy skin and delay skin aging. Skin is the primary barrier that protects the body from external aggressions....
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 867: Effects of Casein Hydrolysate Ingestion on Thermoregulatory Responses in Healthy Adults during Exercise in Heated Conditions: A Randomized Crossover Trial Nutrients doi: 10.3390/nu12030867 Authors: Yasuyuki Sakata Chikako Yoshida Yuka Fujiki Yutaka Matsunaga Hirohiko Nakamura Takashi Shimizu Yasuhiro Takeda Tatsuro Amano Food ingestion has been shown to affect thermoregulation during exercise, while the impact of protein degradant consumption...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 869: Reply to “Comments on the Editor Re: The Relationship of Obesity, Nutritional Status and Muscle Wasting in Patients Assessed for Liver Transplantation, Nutrients 2019, 11, 2097.” Nutrients doi: 10.3390/nu12030869 Authors: Helen Vidot Katharine Kline Robert Cheng Liam Finegan Amelia Lin Elise Kempler Simone I. Strasser David Geoffrey Bowen Geoffrey William McCaughan Sharon Carey Margaret Allman-Farinelli Nicholas Adam Shackel ...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 868: Brassicaceae-Derived Anticancer Agents: Towards a Green Approach to Beat Cancer Nutrients doi: 10.3390/nu12030868 Authors: Mandrich Caputo Cancer is the main cause of mortality and morbidity worldwide. Although a large variety of therapeutic approaches have been developed and translated into clinical protocols, the toxic side effects of cancer treatments negatively impact patients, allowing cancer to grow. Brassica metabolites are emerging as new weapons...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 871: Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells Nutrients doi: 10.3390/nu12030871 Authors: Patti Hayes Claire Fergus Magda Ghanim Cansu Cirzi Lyubomyr Burtnyak Callum J. McGrenaghan Francesca Tuorto Derek P. Nolan Vincent P. Kelly Queuine is a eukaryotic micronutrient, derived exclusively from eubacteria. It is incorporated into both cytosolic and mitochondrial...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 865: Micronutrients Selenomethionine and Selenocysteine Modulate the Redox Status of MCF-7 Breast Cancer Cells Nutrients doi: 10.3390/nu12030865 Authors: Pons Moran Alorda-Clara Oliver Roca Sastre-Serra Selenium is a micronutrient which is found in many foods, with redox status modulation activity. Our aim was to evaluate the effects of two chemical forms of selenoamino acids, Seleno-L-methionine and Seleno-L-cystine (a diselenide derived...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 866: Serum Microelements in Early Pregnancy and their Risk of Large-for-Gestational Age Birth Weight Nutrients doi: 10.3390/nu12030866 Authors: Małgorzata Lewandowska Jan Lubiński Excessive birth weight has serious perinatal consequences, and it “programs” long-term health. Mother’s nutritional status can be an important element in fetal “programming”; microelements such as selenium (Se), zinc (Zn), copper...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 862: Expression Profiles of Genes Encoding Cornified Envelope Proteins in Atopic Dermatitis and Cutaneous T-Cell Lymphomas Nutrients doi: 10.3390/nu12030862 Authors: Magdalena Trzeciak Berenika Olszewska Monika Sakowicz-Burkiewicz Małgorzata Sokołowska-Wojdyło Jerzy Jankau Roman Janusz Nowicki Tadeusz Pawełczyk The skin barrier defect in cutaneous T-cell lymphomas (CTCL) was recently confirmed to be similar to the one observed in atopic dermatitis...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 864: The Relationship Between Body Composition and Muscle Tone in Children with Cerebral Palsy: A Case-Control Study Nutrients doi: 10.3390/nu12030864 Authors: Więch Ćwirlej-Sozańska Wiśniowska-Szurlej Kilian Lenart-Domka Bejer Domka-Jopek Sozański Korczowski The monitoring of children with cerebral palsy (CP) should include a precise assessment of the nutritional status to identify children and adolescents at risk of nutrition...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 863: Prevalence, Risk Factors, and Complications of Oropharyngeal Dysphagia in Older Patients with Dementia Nutrients doi: 10.3390/nu12030863 Authors: Mᵃ Carmen Espinosa-Val Alberto Martín-Martínez Mercè Graupera Olivia Arias Amparo Elvira Mateu Cabré Elisabet Palomera Mireia Bolívar-Prados Pere Clavé Omar Ortega The prevalence of older patients with dementia and oropharyngeal dysphagia (OD) is rising and management is poor. Our aim...
Tue Mar 24, 2020 02:00
Nutrients, Vol. 12, Pages 861: Vitamin D and Abdominal Aortic Calcification in Older African American Women, the PODA Clinical Trial Nutrients doi: 10.3390/nu12030861 Authors: Saloni Brahmbhatt Mageda Mikhail Shahidul Islam John F. Aloia Abdominal aortic calcification (AAC) detected on lateral vertebral fracture assessment is associated with increased cardiovascular risk. Vitamin D deficiency and toxicity have been linked with vascular calcification. The objective of this study...
Tue Mar 24, 2020 02:00
Pathogens, Vol. 9, Pages 244: Rapid Spread of Classical Swine Fever Virus among South Korean Wild Boars in Areas near the Border with North Korea Pathogens doi: 10.3390/pathogens9040244 Authors: Choe Cha Yu Kim Song Choi Jung Lim Hyun Park An There has been a rapid increase in the number of classical swine fever (CSF) sero-positive wild boars captured near the demilitarized zone (DMZ), located the border with North Korea. In 2015–2016,...
Wed Mar 25, 2020 02:00
Pathogens, Vol. 9, Pages 243: In Vitro Anti-NTHi Activity of Haemophilin-Producing Strains of Haemophilus haemolyticus Pathogens doi: 10.3390/pathogens9040243 Authors: Atto Latham Kunde Gell Tristram Nontypeable Haemophilus influenzae (NTHi) is a leading causative organism of opportunistic respiratory tract infections. However, there are currently no effective vaccination strategies, and existing treatments are compromised by antibiotic resistance. We previously characterized...
Wed Mar 25, 2020 02:00
Pathogens, Vol. 9, Pages 242: Detection of Antibodies against Mycobacterium bovis in Oral Fluid from Eurasian Wild Boar Pathogens doi: 10.3390/pathogens9040242 Authors: Barasona Barroso-Arévalo Rivera Gortázar Sánchez-Vizcaíno The presence of Mycobacterium bovis and other members of the Mycobacterium tuberculosis complex (MTC) is a main concern in wildlife populations such as the Eurasian wild boar (Sus scrofa). Tests detecting antibodies against the MTC are valuable...
Wed Mar 25, 2020 02:00
Pathogens, Vol. 9, Pages 245: Predominance of Human Bocavirus Genotype 1 and 3 in Outpatient Children with Diarrhea from Rural Communities in South Africa, 2017–2018 Pathogens doi: 10.3390/pathogens9040245 Authors: Rikhotso Khumela Kabue Traoré-Hoffman Potgieter Human bocavirus (HBoV) is an emerging virus globally associated with diarrhea in young children. This study aims to investigate the prevalence of HBoV genotypes in children (≤ 5 years) from rural communities...
Wed Mar 25, 2020 02:00
Pathogens, Vol. 9, Pages 241: PrPSc with Seeding Activity Extensively Overlaps with Proteinase-Resistant PrPSc Rather than Infectious PrPSc Pathogens doi: 10.3390/pathogens9030241 Authors: Iwamaru Matsuura Miyazawa The disease-associated prion protein (PrPSc) has the ability to seed the conformational conversion of normal prion proteins into the amyloid fibril form. This prion seeding activity can be measured using an in vitro amplification assay termed real-time quaking-induced...
Tue Mar 24, 2020 02:00
Pharmaceuticals, Vol. 13, Pages 52: 4-Amino-1,2,4-triazole-3-thione as a Promising Scaffold for the Inhibition of Serine and Metallo-β-Lactamases Pharmaceuticals doi: 10.3390/ph13030052 Authors: Pasquale Linciano Eleonora Gianquinto Martina Montanari Lorenzo Maso Pierangelo Bellio Esmeralda Cebrián-Sastre Giuseppe Celenza Jesús Blázquez Laura Cendron Francesca Spyrakis Donatella Tondi The emergence of bacteria that co-express serine- and metallo- carbapenemases...
Tue Mar 24, 2020 02:00
Pharmaceutics, Vol. 12, Pages 299: Kinetic Cytokine Secretion Profile of LPS-Induced Inflammation in the Human Skin Organ Culture Pharmaceutics doi: 10.3390/pharmaceutics12040299 Authors: Gvirtz Ogen-Shtern Cohen Several in vitro models that mimic different aspects of local skin inflammation exist. The use of ex vivo human skin organ culture (HSOC) has been reported previously. However, comprehensive evaluation of the cytokine secretory capacity of the system and its kinetics...
Wed Mar 25, 2020 02:00
Pharmaceutics, Vol. 12, Pages 298: Polymeric Nanocarriers of Drug Delivery Systems in Cancer Therapy
Pharmaceutics, Vol. 12, Pages 298: Polymeric Nanocarriers of Drug Delivery Systems in Cancer Therapy Pharmaceutics doi: 10.3390/pharmaceutics12040298 Authors: Avramović Mandić Savić-Radojević Simić Conventional chemotherapy is the most common therapeutic method for treating cancer by the application of small toxic molecules thatinteract with DNA and causecell death. Unfortunately, these chemotherapeutic agents are non-selective and can damage both cancer and healthy tissues,producing...
Wed Mar 25, 2020 02:00
Pharmaceutics, Vol. 12, Pages 296: Effect of Food and an Animal’s Sex on P-Glycoprotein Expression and Luminal Fluids in the Gastrointestinal Tract of Wistar Rats Pharmaceutics doi: 10.3390/pharmaceutics12040296 Authors: Dou Gavins Mai Madla Taherali Orlu Murdan Basit The rat is one of the most commonly used animal models in pre-clinical studies. Limited information between the sexes and the effect of food consumption on the gastrointestinal (GI) physiology,...
Wed Mar 25, 2020 02:00
Pharmaceutics, Vol. 12, Pages 297: Changing the Drug Delivery System: Does It Add to Non-Compliance Ramifications Control? A Simulation Study on the Pharmacokinetics and Pharmacodynamics of Atypical Antipsychotic Drug Pharmaceutics doi: 10.3390/pharmaceutics12040297 Authors: Elkomy This study investigates the pharmacokinetic (PK) and pharmacodynamic (PD) consequences of shifting from Quetiapine fumarate immediate-release (IR) to extended-release (XR) formulation in non-adherent schizophrenia...
Wed Mar 25, 2020 02:00
Pharmaceutics, Vol. 12, Pages 294: An Assessment of Mesoporous Silica Nanoparticle Architectures as Antigen Carriers Pharmaceutics doi: 10.3390/pharmaceutics12030294 Authors: Xinyue Huang Helen E Townley Mesoporous silica nanoparticles (MSNPs) have the potential to be used as antigen carriers due to their high surface areas and highly ordered pore network. We investigated the adsorption and desorption of diphtheria toxoid as a proof-of-concept. Two series of nanoparticles were prepared—(i)...
Tue Mar 24, 2020 02:00
Pharmaceutics, Vol. 12, Pages 295: Segmental-Dependent Solubility and Permeability as Key Factors Guiding Controlled Release Drug Product Development Pharmaceutics doi: 10.3390/pharmaceutics12030295 Authors: Milica Markovic Moran Zur Noa Fine-Shamir Ester Haimov Isabel González-Álvarez Arik Dahan The main factors influencing the absorption of orally administered drugs are solubility and permeability, which are location-dependent and may vary along the gastrointestinal...
Tue Mar 24, 2020 02:00
Pharmaceutics, Vol. 12, Pages 293: Alendronic Acid as Ionic Liquid: New Perspective on Osteosarcoma Pharmaceutics doi: 10.3390/pharmaceutics12030293 Authors: Sónia Teixeira Miguel M. Santos Maria H. Fernandes João Costa-Rodrigues Luís C. Branco Herein the quantitative synthesis of eight new mono- and dianionic Organic Salts and Ionic Liquids (OSILs) from alendronic acid (ALN) is reported by following two distinct sustainable and straightforward methodologies, according to...
Tue Mar 24, 2020 02:00
Pharmaceutics, Vol. 12, Pages 291: Optimal Connection for Tiotropium SMI Delivery through Mechanical Ventilation: An In Vitro Study Pharmaceutics doi: 10.3390/pharmaceutics12030291 Authors: Tien-Pei Fang Yu-Ju Chen Tsung-Ming Yang Szu-Hu Wang Ming-Szu Hung Shu-Hua Chiu Hsin-Hsien Li James B. Fink Hui-Ling Lin We aimed to quantify Soft Mist Inhalers (SMI) delivery to spontaneous breathing model and compare with different adapters via endotracheal tube during mechanical...
Tue Mar 24, 2020 02:00
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