Related ArticlesBurden and emergency department management of acute cough in children. J Paediatr Child Health. 2019 Feb;55(2):181-187 Authors: Anderson-James S, Marchant JM, Chang AB, Acworth JP, Phillips NT, Drescher BJ, Goyal V, O'Grady KF Abstract AIM: In children presenting to an emergency department (ED) with an acute coughing illness, the aims of this study were to: (i) describe the frequency of doctor visits and medication use; and (ii) describe...
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Related ArticlesBronchiolitis obliterans syndrome susceptibility and the pulmonary microbiome. J Heart Lung Transplant. 2018 09;37(9):1131-1140 Authors: Schott C, Weigt SS, Turturice BA, Metwally A, Belperio J, Finn PW, Perkins DL Abstract BACKGROUND: Lung transplantation outcomes remain complicated by bronchiolitis obliterans syndrome (BOS), a major cause of mortality and retransplantation for patients. A variety of factors linking inflammation and...
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Related ArticlesCerebral localization of higher functions: Memory-related anatomic structures. Dement Neuropsychol. 2020 Jan-Mar;14(1):75-79 Authors: Engelhardt E Abstract The nature of memory and the search for its localization have been a subject of interest since Antiquity. After millennia of theoretical concepts, shifting from the heart to the brain, then from the ventricles to solid parts, the core memory-related structures finally began to be identified...
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Related ArticlesPilot Study to Assess the Use of Ultrasound in Evaluating the Abnormal Pediatric Airway. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820912034 Authors: Bell JR, Cohen AP, Graff JT, Fleck RJ, O'Hara S, de Alarcon A, Hart CK Abstract In this study, we sought to explore the feasibility of using ultrasonography to evaluate airway anomalies in awake children with previous airway reconstruction. For the month of December 2018, we reviewed...
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Related ArticlesEffect of Round Window Opening Size on Residual Hearing Preservation in Cochlear Implantation. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820912032 Authors: Gotamco GL, Sun CH, Chou YF, Hsu CJ, Wu HP Abstract OBJECTIVES: This study aims to compare the hearing preservation outcomes in cochlear implant surgery following slit versus full opening of the round window membrane. SETTING: Tertiary referral center. ...
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Related ArticlesThe Trach Safe Initiative: A Quality Improvement Initiative to Reduce Mortality among Pediatric Tracheostomy Patients. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820911728 Authors: Ong T, Liu CC, Elder L, Hill L, Abts M, Dahl JP, Evans KN, Parikh SR, Soares JJ, Striegl AM, Whitlock KB, Johnson KE Abstract OBJECTIVE: To describe the Trach Safe Initiative and assess its impact on unanticipated tracheostomy-related mortality in outpatient...
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Related ArticlesLong-Term Complications of Osteocutaneous Free Flaps in Head and Neck Reconstruction. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820912727 Authors: Swendseid B, Kumar A, Sweeny L, Wax MK, Zhan T, Goldman RA, Krein H, Heffelfinger RN, Luginbuhl AJ, Curry JM Abstract OBJECTIVE: To determine the frequency at which patients with osteocutaneous free flap reconstruction of the head and neck develop long-term complications and identify...
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Related ArticlesReframing Our Approach to Facial Analysis. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820912031 Authors: Miller LE, Kozin ED, Lee LN Abstract Facial analysis is a foundational aspect of facial plastic and reconstructive surgery. Unfortunately, ideal proportions of beauty are commonly discussed without much thought regarding their historical derivation and associated cultural implications. Facial analysis often is limited to narrow...
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Related ArticlesThe Effects of Steroids on Survival of Mouse and Human Tympanic Membrane Fibroblasts. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820912739 Authors: Karnani DN, Dirain CO, Antonelli PJ Abstract OBJECTIVE: Tympanic membrane (TM) fibroblast cytotoxicity of quinolone ear drops is enhanced by dexamethasone and fluocinolone. Hydrocortisone has not been evaluated. We aimed to assess the effects of these 3 steroids on mouse and human...
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Related ArticlesMaxillary Frenulum in Newborns: Association with Breastfeeding. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820913605 Authors: Razdan R, Callaham S, Saggio R, Chafin M, Carr MM Abstract OBJECTIVE: To relate maxillary and lingual frenulum configuration to breastfeeding success. STUDY DESIGN: Cross-sectional study. SETTING: Newborn nursery in tertiary care academic hospital. SUBJECTS AND METHODS: Newborns...
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Related ArticlesAudiometric Outcomes and Middle Ear Disease following Cerebrospinal Fluid Leak Repair. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820911720 Authors: Yancey KL, Manzoor NF, Haynes DS, Bennett ML, O'Malley M, Rivas A Abstract OBJECTIVE: To investigate audiometric outcomes and incidence of chronic ear disease following lateral skull base repair (LSBR) of cerebrospinal fluid (CSF) leaks. STUDY DESIGN: Retrospective review....
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Related ArticlesAssociation of Opioid Quantity and Caregiver Education with Pain Control after Pediatric Tonsillectomy. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820912033 Authors: Harbaugh CM, Vargas G, Sloss KR, Bohm LA, Cooper KA, Thatcher AL, Zopf DA, Chua KP, Waljee JF, Gadepalli SK Abstract OBJECTIVE: To examine whether a service guideline reducing postoperative opioid prescription quantities and caregiver-reported education to use nonopioid...
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Related ArticlesTransoral Robotic Surgery versus Plasma Ablation for Tongue Base Reduction in Obstructive Sleep Apnea: Meta-analysis. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820913533 Authors: Lee JA, Byun YJ, Nguyen SA, Lentsch EJ, Gillespie MB Abstract OBJECTIVES: To compare the effectiveness of transoral robotic surgery (TORS) versus plasma ablation (PA) in tongue base reduction surgery for obstructive sleep apnea (OSA). DATA...
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Related ArticlesEndonasal Endoscopic Surgery for Pediatric Sellar and Suprasellar Lesions: A Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820913637 Authors: Lee JA, Cooper RL, Nguyen SA, Schlosser RJ, Gudis DA Abstract OBJECTIVES: The advent of endonasal endoscopic skull base surgery (ESBS) has redefined the management of pediatric sellar and suprasellar lesions. To date, the outcomes of these procedures have...
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Related ArticlesPresentation and Outcomes of Elderly Patients Undergoing Head and Neck Surgeries: A National Perspective. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820911727 Authors: Al-Qurayshi Z, Sullivan CB, Schwalje A, Walsh J, Bayon R, Tufano R, Kandil E Abstract OBJECTIVES: To examine clinical profile and outcomes of elderly patients (65-90 years) undergoing head and neck surgeries in the United States. STUDY DESIGN: A retrospective...
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Related ArticlesGeographic Heterogeneity in Otolaryngology Medicare New Patient Visits. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820913495 Authors: Hur K, Gibbons J, Finch BK Abstract OBJECTIVE: To analyze the spatial variation of sociodemographic factors associated with the geographic distribution of new patient visits to otolaryngologists. STUDY DESIGN: Retrospective cross-sectional analysis. SETTING: United States. ...
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Related ArticlesEffect of HPV Status on Survival of Oropharynx Cancer with Distant Metastasis. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820913604 Authors: Kaplon AW, Galloway TJ, Bhayani MK, Liu JC Abstract Human papillomavirus (HPV)-positive oropharynx squamous cell carcinoma (OPSCC) is known to have improved survival over HPV-negative disease. However, it is largely unknown whether HPV status similarly affects survival in patients presenting...
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Related ArticlesDevelopment and Validation of a Novel Surgical Simulation for Parotidectomy and Facial Nerve Dissection. Otolaryngol Head Neck Surg. 2020 Mar 24;:194599820913587 Authors: Gabrysz-Forget F, Rubin S, Nepomnayshy D, Dolan R, Yarlagadda B Abstract We present the development and validation of a low-cost novel model for training of parotid surgery. The model consists of a 3-dimensionally printed skeleton, silicone-based soft tissue, and...
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Abstract Endovenous tumor thrombus in abdomen should be accurately diagnosed as it is a significant finding that may change medical and surgical treatment approaches. As some underlying reasons for endovenous tumor thrombi are relatively rare and imaging findings may be quite subtle, they can be easily overlooked which may have important clinical consequences. In this paper, we described the various imaging aspects of endovenous tumor thrombi originating from various tumor types...
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Summary Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease, characterized by hepatic fat accumulation and possible development of inflammation, fibrosis, and cancer. The ketogenic diet (KD), with its drastic carbohydrate reduction, is a now popular weight loss intervention, despite safety concerns on a possible association with fatty liver. However, KDs were also reported to be beneficial on hepatic pathology, with ketone bodies recently proposed as effective modulators...
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Abstract The use of pharmacological treatments for opioid use disorders, including methadone, buprenorphine and naltrexone has been associated with a reduction in mortality compared with illicit opioid use. However, these treatments can also contribute significantly to the risk of death. The opioid agonists methadone and buprenorphine achieve clinical efficacy in patients with an opioid use disorder through suppressing craving and diminishing the effectiveness of illicit opioid...
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Abstract The aim of this study is to determine the attitudes of pre-service teachers towards programming, the perceptions of self-efficacy about block-based programming and the opinions of pre-service teachers on the use of educational robots. This research is a quantitative and qualitative research conducted using a mixed research design. The study group of the research consisted of 140 undergraduate students from the universities in Turkey, studying in the Department of Computer...
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Abstract Whereas blended learning can deliver several benefits to students in higher education, their achievement depends on how exactly it is designed. A participatory design is recommendable to try to meet the needs of all stakeholders. The Persuasive System Design-model can be used to motivate students during the online part of the course. In the design there has to be an optimal blend between the different parts of the course. A participatory design is used to design a blended...
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Abstract This survey-based study explores the nature of Digital Divide among Ghana’s basic (primary and junior high) schools from the perspective of Teachers’ Digital Literacy and their usage of digital technologies in school. The ICT-enhanced Teacher Standards for Africa (ICTeTSA) Framework comprising digital attitude, knowledge, skills and application components was used for measuring the perceived Teacher Digital Literacy, while, the European Union’s rubrics for measuring ICT...
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Abstract Depression is common in women with obstructive sleep apnea (OSA), but objective markers of depression have not yet been explored in such patients. We hypothesized that inflammation and antioxidant biomarkers may be associated with depression in a cohort of OSA women. We conducted a multicentre, cross‐sectional study in 247 women diagnosed with moderate‐to‐severe OSA. Depression was assessed by the depression subscale of the Hospital Anxiety and Depression Questionnaire (HAD‐D) and defined...
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Abstract Several virulence factors of Aeromonas such as hemolysin, proteases and lipases have been characterized. The relationship between these virulence factors and disease remains unclear. A 71‐year‐old man underwent thoracoscopic esophagectomy, lymph node dissection and Roux‐en‐Y reconstruction for esophageal cancer. On postoperative day 1, redness around the wound on the thoracic abdominal wall gradually enlarged and necrosis became apparent with septic shock. Necrotizing soft tissue infection...
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Abstract Bexarotene is useful for both early and advanced cutaneous T‐cell lymphoma (CTCL), and is sometimes applied to ultraviolet‐tolerant early CTCL patients as one of the first‐line therapies in the real world. However, continuous administration of bexarotene is sometimes difficult because of its adverse events (AE). Development of an appropriate protocol for bexarotene that can induce a consistent response for CTCL without severe AE (SAE) is needed. We retrospectively investigated 29 Japanese...
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Abstract Rosacea is a common chronic skin disorder of unknown etiology. While population prevalence rates range 0.2–22% in Europe and North America, prevalence in China is currently undetermined. We conducted a large population‐based case–control study to determine the present epidemiological status of rosacea in China, involving 10 095 participants aged 0–100 years (mean age, 35.5 ± 19.1; 50.5% female). A census of rosacea among 15 communities in Changsha in south central China was conducted with...
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Abstract Reactive neutrophilic dermatoses in adult‐onset immunodeficiency due to interferon‐γ autoantibody (AOID) are usually associated with concomitant active opportunistic infections. Data focusing on the treatment of these dermatoses with non‐immunosuppressive drugs are still lacking. The aim of this study was to assess the efficacy and safety of acitretin treatment of reactive neutrophilic dermatoses in AOID. We conducted a retrospective review of all patients with AOID who had reactive neutrophilic...
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Abstract Background Cardiac resynchronisation therapy (CRT) is a well-established form of treatment for patients with heart failure and cardiac dyssynchrony. There are two different types of CRT devices: the biventricular pacemaker (CRT-P) and the biventricular defibrillator (CRT-D). The latter is more complex but also more expensive. For the majority of patients who are eligible for CRT, both devices are appropriate according to current...
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Abstract Previous studies reported that intrageneric relationships of genus Veratrum of family Melanthiaceae are controversial and hard to delimit. Therefore, we observed the pollen morphological features of six species in the genus Veratrum in detail using both light microscopy and scanning electron microscopy and investigated their significance for Veratrum taxonomy. Among them, five were studied for the first time. The results demonstrated that pollen grains of Veratrum are medium in size with...
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In this study, 1,105 cases of nasopharyngeal carcinoma (NPC) and 1,430 normal controls recruited from Hunan province, southern China were typed for human leukocyte antigen (HLA)‐B locus by Sanger sequencing exons 2‐4. Besides confirming the NPC association with HLA‐B*46:01 allele, HLA‐A*02:07‐B*46:01 and HLA‐A*33:03‐B*58:01 haplotypes (all positive), and HLA‐B*13 lineage (negative), all of which were relatively common, strong negative associations were observed for five low‐frequency and rare alleles...
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Malignant ascites is one of the major clinical features of ovarian cancer, which serves as a carrier for the peritoneal dissemination of tumor cells and predicts a poor prognosis in patients. In the microenvironment of ovarian cancer ascites, anti‐tumor immunity is suppressed, which enables the tumor cells to escape from immune surveillance. The metabolic factors, including hypoxia, nutrient deprivation, and accumulation of metabolic products, contribute to the immunosuppressive status of malignant...
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Abstract Purpose Foreign body (FB) ingestions represent a common problem in children. History and physical examination are commonly not enough to diagnose a foreign body ingestion; therefore, conventional radiography is routinely used to detect them. Point-of-care ultrasound is widely used in the emergency department for several diagnostic applications but there are few articles describing the possibility to use point-of-care ultrasound...
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Abstract The criteria used by International Union for Conservation of Nature (IUCN) for its Red List of Ecosystems (RLE) are the global standards for ecosystem-level risk assessment, and they have been increasingly used for biodiversity conservation. The changed distribution area of an ecosystem is one of the key criteria in such assessments. The Stipa bungeana grassland is one of the most widely distributed grasslands in the warm-temperate semi-arid regions of China. However,...
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