Microorganisms, Vol. 8, Pages 457: Multicenter Evaluation of the C6 Lyme ELISA Kit for the Diagnosis of Lyme Disease Microorganisms doi: 10.3390/microorganisms8030457 Authors: Silvia Zannoli Michela Fantini Simona Semprini Barbara Marchini Barbara Ceccarelli Monica Sparacino Pasqua Schiavone Anna Belgrano Maurizio Ruscio Martina Gobbetti Maira Nicoletti Eva Robatscher Elisabetta Pagani Vittorio Sambri Lyme disease (LD), caused by infection with...
Tue Mar 24, 2020 02:00
Molecules, Vol. 25, Pages 1490: Bifidobacterium animalis subsp. lactis A6 Alleviates Obesity Associated with Promoting Mitochondrial Biogenesis and Function of Adipose Tissue in Mice Molecules doi: 10.3390/molecules25071490 Authors: Huo Lu Wang Wang Chen Guo Zhang Li Probiotics are widely known for their health benefits. Mitochondrial dysfunction is related to obesity. The aim of this study was to illuminate whether Bifidobacterium animalis subsp. lactis...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1500: Probing the Protein-Protein Interaction Between the ATRXADD Domain and the Histone H3 Tail Molecules doi: 10.3390/molecules25071500 Authors: Zaino Dash Hadden While loss-of-function mutations in the ATRX gene have been implicated as a driving force for a variety of pediatric brain tumors, as well as pancreatic neuroendocrine tumors, the role of ATRX in gene regulation and oncogenic development is not well-characterized. The ADD domain of ATRX...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1499: Probing the Interfacial Behavior of Type IIIa Binary Mixtures Along the Three-Phase Line Employing Molecular Thermodynamics Molecules doi: 10.3390/molecules25071499 Authors: Alonso Chaparro Cartes Müller Mejía Interfacial properties such as interfacial profiles, surface activity, wetting transitions, and interfacial tensions along the three-phase line are described for a Type IIIa binary mixture. The methodological approach combines the...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1498: Synthesis of Pyrrolidine Monocyclic Analogues of Pochonicine and Its Stereoisomers: Pursuit ofSimplified Structures and Potent β-N-Acetylhexosaminidase Inhibition Molecules doi: 10.3390/molecules25071498 Authors: Yan Shimadate Kato Li Jia Fleet Yu Ten pairs of pyrrolidine analogues of pochonicine and its stereoisomers have been synthesized from four enantiomeric pairs of polyhydroxylated cyclic nitrones. Among the ten N-acetylamino...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1497: Multitarget Anticancer Agents Based on Histone Deacetylase and Protein Kinase CK2 inhibitors Molecules doi: 10.3390/molecules25071497 Authors: Regina Martínez Bruno Di Geronimo Miryam Pastor José María Zapico Claire Coderch Rostyslav Panchuk Nadia Skorokhyd Maciej Maslyk Ana Ramos Beatriz de Pascual-Teresa The design of multitarget drugs (MTDs) has become an innovative approach for the search of effective treatments in complex...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1501: Analytical Detection of Sulfonamides and Organophosphorus Insecticide Residues in Fish in Taiwan Molecules doi: 10.3390/molecules25071501 Authors: Chang Hou Yang Wu Chang Tsai Tsai Lin Xue Wang Chang Exposure to residues of antibiotics (e.g., sulfonamides) and insecticides (e.g., organophosphorus insecticides) in aquacultured food can adversely affect humans and animals and thus affect public health globally. Here,...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1495: Band-Gap Energies of Choline Chloride and Triphenylmethylphosphoniumbromide-Based Systems Molecules doi: 10.3390/molecules25071495 Authors: Alberto Mannu Maria Enrica Di Pietro Andrea Mele UV–VIS spectroscopy analysis of six mixtures containing choline chloride or triphenylmethylphosphonium bromide as the hydrogen bond acceptor (HBA) and different hydrogen bond donors (HBDs, nickel sulphate, imidazole, d-glucose, ethylene glycol, and glycerol)...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1494: In Vitro Bioactivity and Biocompatibility of Bio-Inspired Ti-6Al-4V Alloy Surfaces Modified by Combined Laser Micro/Nano Structuring Molecules doi: 10.3390/molecules25071494 Authors: Li Yang Yang Shi Yang Cheng The bioactivity and biocompatibility play key roles in the success of dental and orthopaedic implants. Although most commercial implant systems use various surface microstructures, the ideal multi-scale topographies capable...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1493: Special Issue: “Advances in Homogeneous Catalysis” Molecules doi: 10.3390/molecules25071493 Authors: García-Álvarez The use of enzymes, organo-catalysts or transition metal catalysts, as opposed to the employment of stoichiometric quantities of other traditional promoters of different organic synthetic processes (like, inorganic/organic bases, Brønsted acids, radicals, etc.) has allowed the discovery of a great number of new synthetic protocols...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1492: Korean Red Ginseng Plays An Anti-Aging Role by Modulating Expression of Aging-Related Genes and Immune Cell Subsets Molecules doi: 10.3390/molecules25071492 Authors: Shin Yi Kim Kim Hossain Kim Cho Despite previous reports of anti-aging effects of Korean red ginseng (KRG), the underlying mechanisms remain poorly understood. Therefore, this study investigated possible mechanisms of KRG-mediated anti-aging effects in aged mice. KRG...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1491: NMR Lipid Profile of Milk from Alpine Goats with Supplemented Hempseed and Linseed Diets Molecules doi: 10.3390/molecules25071491 Authors: Antonella Caterina Boccia Erica Cusano Paola Scano Roberto Consonni The supplementation of goat diets with natural products to obtain milk with nutraceutical components is a common practice. In these last years, the influence of supplementation of specifically designed diets has been studied with different...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1489: Glucocorticoids Influencing Wnt/β-Catenin Pathway; Multiple Sites, Heterogeneous Effects Molecules doi: 10.3390/molecules25071489 Authors: Meszaros Patocs Glucocorticoid hormones are vital; their accurate operation is a necessity at all ages and in all life situations. Glucocorticoids regulate diverse physiological processes and they use many signaling pathways to fulfill their effect. As the operation of these hormones affects many organs, the excess...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1488: Synthesis and Antibacterial Evaluation of Novel 1,3,4-Oxadiazole Derivatives Containing Sulfonate/Carboxylate Moiety Molecules doi: 10.3390/molecules25071488 Authors: Wang Zhou Lu Mu Jin Abstract: In order to discover new lead compounds with high antibacterial activity, a series of new derivatives were designed and synthesized by introducing a sulfonate or carboxylate moiety into the 1,3,4-oxadiazole structure. Antibacterial activity against...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1496: Distribution of Lactoferrin Is Related with Dynamics of Neutrophils in Bacterial Infected Mice Intestine Molecules doi: 10.3390/molecules25071496 Authors: Li Liang Zhen-Jie Wang Guang Ye Xue-You Tang Yuan-Yuan Zhang Jing-Xia Kong Hua-Hua Du Lactoferrin (Lf) is a conserved iron-binding glycoprotein with antimicrobial activity, which is present in secretions that recover mucosal sites regarded as portals of invaded pathogens. Although numerous...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1486: Serjanic Acid Improves Immunometabolic Markers in a Diet-Induced Obesity Mouse Model Molecules doi: 10.3390/molecules25071486 Authors: Gutiérrez Giraldo-Dávila Combariza Holzgrabe Tabares-Guevara Ramírez-Pineda Acín Muñoz Montoya Balcazar Plant extracts from Cecropia genus have been used by Latin-American traditional medicine to treat metabolic disorders and diabetes. Previous reports have shown that roots of Cecropia...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1487: Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses Molecules doi: 10.3390/molecules25071487 Authors: Valeria Francesconi Elena Cichero Silvia Schenone Lieve Naesens Michele Tonelli Respiratory RNA viruses are responsible for recurrent acute respiratory illnesses that still represent a major medical need. Previously we developed a large variety of benzimidazole...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1485: Protein Extraction, Enrichment and MALDI MS and MS/MS Analysis from Bitter Orange Leaves (Citrus aurantium) Molecules doi: 10.3390/molecules25071485 Authors: Donatella Aiello Carlo Siciliano Fabio Mazzotti Leonardo Di Donna Roberta Risoluti Anna Napoli Citrus aurantium is a widespread tree in the Mediterranean area, and it is mainly used as rootstock for other citrus. In the present study, a vacuum infiltration centrifugation procedure,...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1484: Green Tea Catechins Trigger Immediate-Early Genes in the Hippocampus and Prevent Cognitive Decline and Lifespan Shortening Molecules doi: 10.3390/molecules25071484 Authors: Keiko Unno Monira Pervin Kyoko Taguchi Tomokazu Konishi Yoriyuki Nakamura Senescence-accelerated mouse prone 10 (SAMP10) mice, after ingesting green tea catechins (GT-catechin, 60 mg/kg), were found to have suppressed aging-related decline in brain function. The dose dependence...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1482: Studying and Modeling of the Extraction Properties of the Natural Deep Eutectic Solvent and Sorbitol-Based Solvents in Regard to Biologically Active Substances from Glycyrrhizae Roots Molecules doi: 10.3390/molecules25071482 Authors: Boyko Zhilyakova Malyutina Novikov Pisarev Abramovich Potanina Lazar Mizina Sahaidak-Nikitiuk The purpose of this work was the studying and modeling of the extraction properties of the...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1481: Characterization and Application of Pomegranate Epicarp Extracts as Functional Ingredients in a Typical Brazilian Pastry Product Molecules doi: 10.3390/molecules25071481 Authors: Felipe da Silva Veloso Cristina Caleja Ricardo C. Calhelha Tânia C.S. Pires Maria José Alves Lillian Barros Aziza K. Genena João C.M. Barreira Isabel C.F.R. Ferreira Currently, there is a clear tendency to incorporate natural ingredients into food and pharmaceutical...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1483: Development of Cycloaliphatic Epoxy-POSS Nanocomposite Matrices with Lambas Enhanced Resistance to Atomic Oxygen Molecules doi: 10.3390/molecules25071483 Authors: Rivera Lopez Martin Stacey Gamage Suliga Viquerat Scarpa Hamerton The preparation of ultra-thin CFRP laminates, which incorporate a cycloaliphatic epoxy resin reinforced with polyhedral oligomeric silsesquioxane (POSS) reagent nanofiller, using out-of-autoclave procedure...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1478: New Substituted Benzoylthiourea Derivatives: From Design to Antimicrobial Applications Molecules doi: 10.3390/molecules25071478 Authors: Carmen Limban Mariana Carmen Chifiriuc Miron Teodor Caproiu Florea Dumitrascu Marilena Ferbinteanu Lucia Pintilie Amalia Stefaniu Ilinca Margareta Vlad Coralia Bleotu Luminita Gabriela Marutescu Diana Camelia Nuta The increasing threat of antimicrobial resistance to all currently available...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1479: A New Hybrid δ-Lactone Induces Apoptosis and Potentiates Anticancer Activity of Taxol in HL-60 Human Leukemia Cells Molecules doi: 10.3390/molecules25071479 Authors: Gach-Janczak Drogosz-Stachowicz Długosz-Pokorska Jakubowski Janecki Szymański Janecka In the search for new drug candidates, researchers turn to natural substances isolated from plants which may be either used directly or may serve as a source for chemical modifications....
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1480: ‘Acridines’ as New Horizons in Antifungal Treatment Molecules doi: 10.3390/molecules25071480 Authors: Iwona Gabriel Frequent fungal infections in immunocompromised patients and mortality due to invasive mycosis are important clinical problems. Opportunistic pathogenic Candida species remain one of the leading causes of systemic mycosis worldwide. The repertoire of antifungal chemotherapeutic agents is very limited. Although new antifungal drugs such as...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1477: Cellular Internalization of Beta-Carotene Loaded Polyelectrolyte Multilayer Capsules by Raman Mapping Molecules doi: 10.3390/molecules25071477 Authors: Loredana F. Leopold Oana Marișca Ioana Oprea Dumitrița Rugină Maria Suciu Mădălina Nistor Maria Tofană Nicolae Leopold Cristina Coman Raman mapping is becoming a very useful tool in investigating cells and cellular components, as well as bioactive molecules intracellularly. In this...
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1476: Influence of Selected Antidepressants on the Ciliated Protozoan Spirostomum ambiguum: Toxicity, Bioaccumulation, and Biotransformation Products Molecules doi: 10.3390/molecules25071476 Authors: Grzegorz Nałęcz-Jawecki Milena Wawryniuk Joanna Giebułtowicz Adam Olkowski Agata Drobniewska The present study aimed to evaluate the effect of the most common antidepressants on aquatic protozoa. Spirostomum ambiguum was used as the model protozoan....
Wed Mar 25, 2020 02:00
Molecules, Vol. 25, Pages 1474: Alternative Woods in Enology: Characterization of Tannin and Low Molecular Weight Phenol Compounds with Respect to Traditional Oak Woods. A Review Molecules doi: 10.3390/molecules25061474 Authors: Martínez-Gil del Alamo-Sanza Sánchez-Gómez Nevares Wood is one of the most highly valued materials in enology since the chemical composition and sensorial properties of wine change significantly when in contact with it. The need for wood in cooperage...
Tue Mar 24, 2020 02:00
Molecules, Vol. 25, Pages 1473: A Powdered Simulant of Triacetone Triperoxide (TATP) for Safe Testing of X-ray Transmission Screening Equipment Molecules doi: 10.3390/molecules25061473 Authors: Mitja Vahčič David Anderson John Seghers Hanne Leys Miguel Ruiz Oses Grzegorz Rarata Maximino Fernández García Rosana Prados Román Daniel Pellico Escudero Explosives detection systems (EDS) based on X-ray are used at airports to screen baggage for the presence of explosives....
Tue Mar 24, 2020 02:00
Molecules, Vol. 25, Pages 1468: Impact of Pd Loading on CO2 Reduction Performance over Pd/TiO2 with H2 and H2O Molecules doi: 10.3390/molecules25061468 Authors: Akira Nishimura Tadaaki Inoue Yoshito Sakakibara Masafumi Hirota Akira Koshio Eric Hu This study investigated the impact of molar ratio of CO2 to reductants H2O and H2, as well as Pd loading weight on CO2 reduction performance with Pd/TiO2 as the photocatalyst. The Pd/TiO2 film photocatalyst is prepared by the...
Tue Mar 24, 2020 02:00
Molecules, Vol. 25, Pages 1475: Investigating the Fluid–Solid Interaction of Acid Nonionic Nanoemulsion with Carbonate Porous Media Molecules doi: 10.3390/molecules25061475 Authors: Cláudio Regis dos Santos Lucas Yanne Katiussy Pereira Gurgel Aum Edson de Andrade Araújo Tereza Neuma de Castro Dantas Elayne Andrade Araújo Talles Nóbrega Sousa Pedro Tupã Pandava Aum The subject of rock–fluid interaction is important in cases where flow through porous media is...
Tue Mar 24, 2020 02:00
Molecules, Vol. 25, Pages 1462: Dynamic Flow Approaches for Automated Radiochemical Analysis in Environmental, Nuclear and Medical Applications Molecules doi: 10.3390/molecules25061462 Authors: Jixin Qiao Automated sample processing techniques are desirable in radiochemical analysis for environmental radioactivity monitoring, nuclear emergency preparedness, nuclear waste characterization and management during operation and decommissioning of nuclear facilities, as well as medical isotope...
Tue Mar 24, 2020 02:00
Molecules, Vol. 25, Pages 1471: Current Landscape and Emerging Fields of PET Imaging in Patients with Brain Tumors Molecules doi: 10.3390/molecules25061471 Authors: Jan-Michael Werner Philipp Lohmann Gereon R. Fink Karl-Josef Langen Norbert Galldiks The number of positron-emission tomography (PET) tracers used to evaluate patients with brain tumors has increased substantially over the last years. For the management of patients with brain tumors, the most important indications...
Tue Mar 24, 2020 02:00
Molecules, Vol. 25, Pages 1472: Photocrosslinking of cDNA Display Molecules with Their Target Proteins as a New Strategy for Peptide Selection Molecules doi: 10.3390/molecules25061472 Authors: Takuya Terai Tomoyuki Koike Naoto Nemoto Binding peptides for given target molecules are often selected in vitro during drug discovery and chemical biology research. Among several display technologies for this purpose, complementary DNA (cDNA) display (a covalent complex of a peptide and...
Tue Mar 24, 2020 02:00
Molecules, Vol. 25, Pages 1470: Environmental Risk and Risk of Resistance Selection Due to Antimicrobials’ Occurrence in Two Polish Wastewater Treatment Plants and Receiving Surface Water Molecules doi: 10.3390/molecules25061470 Authors: Joanna Giebułtowicz Grzegorz Nałęcz-Jawecki Monika Harnisz Dawid Kucharski Ewa Korzeniewska Grażyna Płaza In this study, a screening of 26 selected antimicrobials using liquid chromatography coupled to a tandem mass spectrometry method...
Tue Mar 24, 2020 02:00
Molecules, Vol. 25, Pages 1467: Microwave Assisted Synthesis of 4-Phenylquinazolin-2(1H)-one Derivatives that Inhibit Vasopressor Tonus in Rat Thoracic Aorta Molecules doi: 10.3390/molecules25061467 Authors: Rafaela Teixeira Talita Menengat Gabriel Andrade Bruno Cotrim Cristiano Ponte Wilson C. Santos Gabriel Resende Quinazolinones have pharmacological effects on vascular reactivity through different mechanisms. We synthesized 4-phenylquinazolin-2(1H)-one derivatives...
Tue Mar 24, 2020 02:00
Molecules, Vol. 25, Pages 1464: Effect of Instant Controlled Pressure-Drop on the Non-Nutritional Compounds of Seeds and Sprouts of Common Black Bean (Phaseolus vulgaris L.) Molecules doi: 10.3390/molecules25061464 Authors: Anaberta Cardador-Martínez Yara Martínez-Tequitlalpan Tzayhri Gallardo-Velazquez Xariss M. Sánchez-Chino Jorge Martínez-Herrera Luis Jorge Corzo-Ríos Cristian Jiménez-Martínez The common bean is an important caloric-protein food source. However,...
Tue Mar 24, 2020 02:00
Molecules, Vol. 25, Pages 1469: Effect of GDM Pairing on PEMFC Performance in Flow-Through and Dead-Ended Anode Mode Molecules doi: 10.3390/molecules25061469 Authors: Yannick Garsany Cornelius H. Bancroft Robert W. Atkinson III Keith Bethune Benjamin D. Gould Karen E. Swider-Lyons Asymmetric gas diffusion media (GDM) pairing, which feature distinct GDM at the anode and cathode of the proton electrolyte membrane fuel cell (PEMFC), enhance water management compared to symmetric...
Tue Mar 24, 2020 02:00
Molecules, Vol. 25, Pages 1465: Antagonists of Vitamin K—Popular Coumarin Drugs and New Synthetic and Natural Coumarin Derivatives Molecules doi: 10.3390/molecules25061465 Authors: Kinga Kasperkiewicz Michał B. Ponczek Jacek Owczarek Piotr Guga Elżbieta Budzisz Many natural coumarins and their chemically synthesized analogs and derivatives exert diverse properties, such as anticancer, antioxidant, anti-inflammatory, or anticoagulant, with the latter being of the utmost importance....
Tue Mar 24, 2020 02:00
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