Related ArticlesFlavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer. Front Oncol. 2019;9:660 Authors: Moreau M, Ibeh U, Decosmo K, Bih N, Yasmin-Karim S, Toyang N, Lowe H, Ngwa W Abstract Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. One of the significant barriers to effective treatment is the immunosuppressive...
Related ArticlesTuberculosis Infection in a Patient Treated With Nivolumab for Non-small Cell Lung Cancer: Case Report and Literature Review. Front Oncol. 2019;9:659 Authors: van Eeden R, Rapoport BL, Smit T, Anderson R Abstract Nivolumab (PD-1 inhibitor) and other immune checkpoint inhibitors are used primarily to promote reactivation of anti-tumor immunity. However, due to their generalized immunorestorative properties, these agents may also trigger...
Related ArticlesCorrigendum: Uterine Adenosarcoma: A Retrospective 12-Year Single-Center Study. Front Oncol. 2019;9:657 Authors: Yuan Z, Yu M, Shen K, Yang J, Cao D, Zhang Y, Zhou H, Wu H Abstract [This corrects the article DOI: 10.3389/fonc.2019.00237.].PMID: 31396483 [PubMed - in process]
Related ArticlesPrognostic Significance of Tumor-Associated Macrophage Content in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis. Front Oncol. 2019;9:656 Authors: Kumar AT, Knops A, Swendseid B, Martinez-Outschoom U, Harshyne L, Philp N, Rodeck U, Luginbuhl A, Cognetti D, Johnson J, Curry J Abstract Background: Head and neck squamous cell carcinoma (HNSCC) exists within a microenvironment rich in immune cells. Macrophages are particularly abundant...
Related ArticlesMRD in AML: The Role of New Techniques. Front Oncol. 2019;9:655 Authors: Voso MT, Ottone T, Lavorgna S, Venditti A, Maurillo L, Lo-Coco F, Buccisano F Abstract In the context of precision medicine, assessment of minimal residual disease (MRD) has been used in acute myeloid leukemia (AML) to direct individual treatment programs, including allogeneic stem cell transplantation in patients at high-risk of relapse. One of the limits of this...
Related ArticlesEI24, as a Component of Autophagy, Is Involved in Pancreatic Cell Proliferation. Front Oncol. 2019;9:652 Authors: Hwang M, Jun DW, Kang EH, Yoon KA, Cheong H, Kim YH, Lee CH, Kim S Abstract Autophagy is a highly conserved cellular process in which cytoplasmic materials are degraded and recycled as energy sources when nutrient supplies are lacking. Established tumor cells require autophagy for cell growth and tumor promotion. In particular,...
Related ArticlesImpact of Different Types of Lymphadenectomy Combined With Different Extents of Tumor Resection on Survival Outcomes of Stage I Non-small-cell Lung Cancer: A Large-Cohort Real-World Study. Front Oncol. 2019;9:642 Authors: Wang W, Chen D, Xi K, Chen Y, Zhang X, Wen Y, Huang Z, Yu X, Wang G, Zhang R, Zhang L Abstract Background: To investigate the prognostic impact of different types of lymphadenectomy with different extents of tumor resection...
Related ArticlesAfatinib for Advanced Non-small Cell Lung Cancer in a Case With an Uncommon Epidermal Growth Factor Receptor Mutation (G719A) Identified in the Cerebrospinal Fluid. Front Oncol. 2019;9:628 Authors: Ma C, Huang C, Tang D, Ye X, Li Z, Liu R, Mu N, Li J, Jiang R, Zhang J Abstract Few previous studies of patients with non-small cell lung cancer (NSCLC) and leptomeningeal metastases have used liquid biopsy of cerebrospinal fluid (CSF) to identify...
Related ArticlesMethylenetetrahydrofolate Reductase Gene C677T and A1298C Polymorphic Sequence Variations Influences the Susceptibility to Chronic Myeloid Leukemia in Kashmiri Population. Front Oncol. 2019;9:612 Authors: Baba SM, Shah ZA, Javaid K, Pandith AA, Rasool J, Geelani SA, Baba RA, Amin S, Mohammad G Abstract Background: Methylenetetrahydrofolate reductase (MTHFR) gene is a crucial regulator of folate metabolism and its two prominent polymorphic...
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Related ArticlesCervical myogenic potentials and controlled postural responses elicited by a prototype vestibular implant. J Neurol. 2019 Aug 08;: Authors: Fornos AP, van de Berg R, Armand S, Cavuscens S, Ranieri M, Crétallaz C, Kingma H, Guyot JP, Guinand N Abstract Gaze stabilization and postural control are two key functions of the vestibular system. In consequence, oscillopsia and chronic imbalance are the two main complaints of patients presenting...
Related ArticlesProspective study of anxiety, post-traumatic stress and depression on postural control, gait, otolith and visuospatial function in military service members with persistent post-concussive symptoms. Undersea Hyperb Med. 2019 BIMA Special Edition No. Feb;46(3):271-287 Authors: Meehan A, Lewandowski A, Weaver LK, Hebert D, Deru K Abstract Purpose: Military service members often report both affective and vestibular complaints after mild traumatic...
Related ArticlesReference ranges and stability of auditory and vestibular measures in a comprehensive assessment battery for traumatic brain injury. Undersea Hyperb Med. 2019 BIMA Special Edition No. Feb;46(3):227-241 Authors: Meehan A, Lewandowski A, Deru K, Hebert D, Weaver LK Abstract Background: Audiology clinics have many tools available to evaluate auditory and vestibular complaints. However, many tools lack established normative ranges across...
Related ArticlesAnterior Cervical Disc Fusion Does not Affect the Presence of Cervical Vestibular-Evoked Myogenic Potential. J Int Adv Otol. 2017 Dec;13(3):368-373 Authors: Kastanioudakis I, Saravakos P, Zigouris A, Ragos V, Reichel O, Ziavra N Abstract OBJECTIVE: Cervical spondylosis and cervical disk herniation are the most frequent forms of degenerative disease in the cervical spine. Surgical treatment mainly includes anterior cervical disk fusion....
Related ArticlesThe Value of Vestibular Rehabilitation in Patients with Bilateral Vestibular Dysfunction. J Int Adv Otol. 2017 Dec;13(3):385-389 Authors: Şahin E, Dinç ME, Yayla Özker B, Çöpürgensli C, Konaklıoğlu M, Özçelik T Abstract OBJECTIVE: The value of vestibular rehabilitation in patients with bilateral vestibular dysfunction was investigated. MATERIALS AND METHODS: This study assessed 17 patients (9 males, 8 females) with bilateral...
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Related ArticlesThe effect of epidermal growth factor on the pseudo-healing of traumatic tympanic membrane perforations. Braz J Otorhinolaryngol. 2019 Jul 27;: Authors: Lou Z Abstract INTRODUCTION: Traumatic tympanic membrane perforations tend to heal spontaneously. However, in this study, several perforations exhibited abnormal healing, where the morphology of healing tympanic membranes differed from that of non-perforated tympanic membranes. Pseudo-healing...
Related ArticlesEvaluation of survival of patients with locally advanced head and neck cancer treated in a single center. Braz J Otorhinolaryngol. 2019 Jul 23;: Authors: Santos FMD, Viani GA, Pavoni JF Abstract INTRODUCTION: Even with improved treatment outcomes with multimodality approaches, the question of what is the best initial treatment for locally advanced head and neck cancer still remains unanswered. OBJECTIVE: To review the overall...
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Related ArticlesCorrection. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3399 Authors: PMID: 31397189 [PubMed - in process]
Related ArticlesThe potential value of lncRNA-BC050642 in osteosarcoma origination and outcomes. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):1859-1866 Authors: Yang Y, Fei M, Zhou X, Li Y, Jin D Abstract Background: The purpose of our research was to explore potential value of lncRNA-BC050642 in osteosarcoma origination and prognosis. Methods: In this study, the tissue specimens were collected from 97 osteosarcoma patients and 97 age-matched healthy...
Related ArticlesEvaluation of antiarthritic activity of nimbolide against Freund's adjuvant induced arthritis in rats. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3391-3398 Authors: Cui X, Wang R, Bian P, Wu Q, Seshadri VDD, Liu L Abstract Nimbolide, a triterpenoid isolated from flower of neem tree possess various therapeutic properties. The objective of the study was to assess the anti-arthritic activity of nimbolide in arthritis induced rats. Nimbolide...
Related ArticlesSirt1 modulates H3 phosphorylation and facilitates osteosarcoma cell autophagy. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3374-3381 Authors: Ying H, Ying B, Zhang J, Kong D Abstract Abnormal histone modifications have been recognized as an important contributing factor to the initiation and progression of osteosarcoma. Sirtuin 1 (Sirt1) up-regulation has been discovered in osteosarcoma cells. This study tested the influence of Sirt1...
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Related ArticlesSacituzumab govitecan: breakthrough targeted therapy for triple-negative breast cancer. Expert Rev Anticancer Ther. 2019 Aug 09;: Authors: Weiss J, Glode A, Messersmith WA, Diamond JR Abstract Introduction: Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype associated with an increased risk of recurrence and cancer-related death. Unlike hormone receptor-positive or HER2-positive breast cancers, there are limited...
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Related ArticlesThe Reconstruction of the Central Tubercle in Bilateral Cleft Lips: Bilateral Lateral Mucosal Advancement Flap With Reinforcement of the Orbicularis Oris Muscle. Ann Plast Surg. 2019 Aug 06;: Authors: Chung J, Lim J, Kim S, Koo Y Abstract BACKGROUND: There are various methods to correct the whistle deformity in bilateral cleft lip. In case of the central deficiency with concomitant lateral excess, local tissue rearrangement can be used...
Related ArticlesScalp Avulsion Injuries and Replantation: Is Deep Temporal Artery an Alternate Option? Ann Plast Surg. 2019 Aug 07;: Authors: Kashyap N, Singhal M, Tiwari R, Chauhan S, Manas R Abstract Scalp avulsion injuries are usually attributed to entrapment of long hair or clothing in agricultural or industrial machinery or traffic accidents. Though rare, these injuries may be dangerous, and resulting cosmetic defect and alopecia lead to social...
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Related Articles[A case of rare laryngeal neurogenic tumor]. Wiad Lek. 2019;72(7):1413-1414 Authors: Czubak J, Frączek M, Morawski K Abstract Laryngeal schwannoma is a rare benign tumour of the larynx. Schwannomas derive from the Schwann cells. Magnetic resonance imaging (MRI) is the best imaging tool for suggesting the diagnosis. We report case of laryngeal schwannoma. The case was a 61-year-old man with a 1-year history of dysphonia and stridor. Laryngoscopy...
Related ArticlesEndoscopic Findings in a Professional Singer With Frequent Throat Clearing. Ear Nose Throat J. 2019 Mar;98(3):128 Authors: Dhar S, Mattioni J, Sataloff RT PMID: 30938244 [PubMed - indexed for MEDLINE]
Related ArticlesPlain Language Summary: Hoarseness (Dysphonia). Otolaryngol Head Neck Surg. 2018 03;158(3):427-431 Authors: Krouse HJ, Reavis CCW, Stachler RJ, Francis DO, O'Connor S Abstract This plain language summary for patients serves as an overview in explaining hoarseness (dysphonia). The summary applies to patients in all age groups and is based on the 2018 "Clinical Practice Guideline: Hoarseness (Dysphonia) (Update)." The evidence-based guideline...
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Related ArticlesExploring the Potential Role of Rosmarinic Acid in Neuronal Differentiation of Human Amnion Epithelial Cells by Microarray Gene Expression Profiling. Front Neurosci. 2019;13:779 Authors: Ferdousi F, Sasaki K, Uchida Y, Ohkohchi N, Zheng YW, Isoda H Abstract In the present study, we conducted microarray gene expression profiling to explore the direction of differentiation of human amnion epithelial cells (hAECs) treated with rosmarinic...
Related ArticlesAltered Topology of the Structural Brain Network in Patients With Post-stroke Depression. Front Neurosci. 2019;13:776 Authors: Xu X, Tang R, Zhang L, Cao Z Abstract There is a pressing need to further our understanding of the mechanisms underlying the depression symptoms in patients with post-stroke depression (PSD) in order to inform targeted therapeutic approaches. While previous research has demonstrated a reorganization in the functional...
Related ArticlesInvestigating the Feasibility of Epicranial Cortical Stimulation Using Concentric-Ring Electrodes: A Novel Minimally Invasive Neuromodulation Method. Front Neurosci. 2019;13:773 Authors: Khatoun A, Asamoah B, Mc Laughlin M Abstract Background: Invasive cortical stimulation (ICS) is a neuromodulation method in which electrodes are implanted on the cortex to deliver chronic stimulation. ICS has been used to treat neurological disorders...
Related ArticlesCurrent Directions in the Auricular Vagus Nerve Stimulation II - An Engineering Perspective. Front Neurosci. 2019;13:772 Authors: Kaniusas E, Kampusch S, Tittgemeyer M, Panetsos F, Gines RF, Papa M, Kiss A, Podesser B, Cassara AM, Tanghe E, Samoudi AM, Tarnaud T, Joseph W, Marozas V, Lukosevicius A, Ištuk N, Lechner S, Klonowski W, Varoneckas G, Széles JC, Šarolić A Abstract Electrical stimulation of the auricular vagus nerve (aVNS) is...
Related ArticlesEditorial: The Alzheimer's Disease Challenge. Front Neurosci. 2019;13:768 Authors: Alexiou A, Kamal MA, Ashraf GM PMID: 31396043 [PubMed]
Related ArticlesDelayed Effects of Acute Reperfusion on Vascular Remodeling and Late-Phase Functional Recovery After Stroke. Front Neurosci. 2019;13:767 Authors: Durán-Laforet V, Fernández-López D, García-Culebras A, González-Hijón J, Moraga A, Palma-Tortosa S, García-Yébenes I, Vega-Pérez A, Lizasoain I, Moro MÁ Abstract Tissue perfusion is a necessary condition for vessel survival that can be compromised under ischemic conditions. Following stroke,...
Related ArticlesNon-canonical Targets Mediating the Action of Drugs of Abuse: Cocaine at the Sigma-1 Receptor as an Example. Front Neurosci. 2019;13:761 Authors: Su TP Abstract In addition to acting on traditionally recognized receptors or transporters on the plasma membrane, several drugs of abuse, including amphetamine, methamphetamine, nicotine, opioid, cocaine, ketamine, and cannabinoid, have been shown to exert their effects by acting on additional...
Related ArticlesExperiences of Upper Limb Somatosensory Retraining in Persons With Stroke: An Interpretative Phenomenological Analysis. Front Neurosci. 2019;13:756 Authors: Turville ML, Walker J, Blennerhassett JM, Carey LM Abstract Purpose: The aim of this study was to explore experiences of upper limb somatosensory discrimination retraining in persons with stroke. Methods: A qualitative methodology was used within the context of a randomized...
Related ArticlesSparse Coding Using the Locally Competitive Algorithm on the TrueNorth Neurosynaptic System. Front Neurosci. 2019;13:754 Authors: Fair KL, Mendat DR, Andreou AG, Rozell CJ, Romberg J, Anderson DV Abstract The Locally Competitive Algorithm (LCA) is a biologically plausible computational architecture for sparse coding, where a signal is represented as a linear combination of elements from an over-complete dictionary. In this paper we map...
Related ArticlesMaintenance of Fluorescence During Paraffin Embedding of Fluorescent Protein-Labeled Specimens. Front Neurosci. 2019;13:752 Authors: Zhanmu O, Zhao P, Yang Y, Yang X, Gong H, Li X Abstract Paraffin embedding is widely used in microscopic imaging for preparing biological specimens. However, owing to significant fluorescence quenching during the embedding process, it is not compatible with fluorescent-labeling techniques, such as transgenic...
Related ArticlesDownregulated Dopamine Receptor 2 and Upregulated Corticotrophin Releasing Hormone in the Paraventricular Nucleus Are Correlated With Decreased Glucose Tolerance in Rats With Bilateral Substantia Nigra Lesions. Front Neurosci. 2019;13:751 Authors: Zhou L, Ran XR, Hong F, Li GW, Zhu JX Abstract Patients with Parkinson's disease (PD) have a high prevalence of glucose metabolism abnormalities. However, the mechanism underlying these symptoms...
Related ArticlesThe Transition Between Slow-Wave Sleep and REM Sleep Constitutes an Independent Sleep Stage Organized by Cholinergic Mechanisms in the Rostrodorsal Pontine Tegmentum. Front Neurosci. 2019;13:748 Authors: Carrera-Cañas C, Garzón M, de Andrés I Abstract There is little information on either the transition state occurring between slow-wave sleep (SWS) and rapid eye movement (REM) sleep, as well as about its neurobiological bases. This transition...
Related ArticlesFunctional Brain Changes During Mindfulness-Based Cognitive Therapy Associated With Tinnitus Severity. Front Neurosci. 2019;13:747 Authors: Zimmerman B, Finnegan M, Paul S, Schmidt S, Tai Y, Roth K, Chen Y, Husain FT Abstract Mindfulness-based therapies have been introduced as a treatment option to reduce the psychological severity of tinnitus, a currently incurable chronic condition. This pilot study of twelve subjects with chronic tinnitus...
Related ArticlesAltered Regional Homogeneity in Patients With Corneal Ulcer: A Resting-State Functional MRI Study. Front Neurosci. 2019;13:743 Authors: Xu MW, Liu HM, Tan G, Su T, Xiang CQ, Wu W, Li B, Lin Q, Xu XW, Min YL, Liu WF, Gao GP, Shao Y Abstract Objective: To investigate the potential regional homogeneity (ReHo) brain activity changes in patients with corneal ulcer (CU) and their possible relationship with clinical symptoms. Materials...
Related ArticlesDisrupted Regional Cerebral Blood Flow, Functional Activity and Connectivity in Alzheimer's Disease: A Combined ASL Perfusion and Resting State fMRI Study. Front Neurosci. 2019;13:738 Authors: Zheng W, Cui B, Han Y, Song H, Li K, He Y, Wang Z Abstract Recent studies have demonstrated a close relationship between regional cerebral blood flow (rCBF) and resting state functional connectivity changes in normal healthy people. However, little...
Related ArticlesSpatiotemporal Empirical Mode Decomposition of Resting-State fMRI Signals: Application to Global Signal Regression. Front Neurosci. 2019;13:736 Authors: Moradi N, Dousty M, Sotero RC Abstract Resting-state functional connectivity MRI (rs-fcMRI) is a common method for mapping functional brain networks. However, estimation of these networks is affected by the presence of a common global systemic noise, or global signal (GS). Previous studies...
Related ArticlesTargeting the Synapse in Alzheimer's Disease. Front Neurosci. 2019;13:735 Authors: Jackson J, Jambrina E, Li J, Marston H, Menzies F, Phillips K, Gilmour G Abstract Dynamic gain and loss of synapses is fundamental to healthy brain function. While Alzheimer's Disease (AD) treatment strategies have largely focussed on beta-amyloid and tau protein pathologies, the synapse itself may also be a critical endpoint to consider regarding disease...
Related ArticlesRe-thinking the Etiological Framework of Neurodegeneration. Front Neurosci. 2019;13:728 Authors: Castillo X, Castro-Obregón S, Gutiérrez-Becker B, Gutiérrez-Ospina G, Karalis N, Khalil AA, Lopez-Noguerola JS, Rodríguez LL, Martínez-Martínez E, Perez-Cruz C, Pérez-Velázquez J, Piña AL, Rubio K, García HPS, Syeda T, Vanoye-Carlo A, Villringer A, Winek K, Zille M Abstract Neurodegenerative diseases are among the leading causes of disability...
Related ArticlesBrain Modulatory Effects by Low-Intensity Transcranial Ultrasound Stimulation (TUS): A Systematic Review on Both Animal and Human Studies. Front Neurosci. 2019;13:696 Authors: Wang P, Zhang J, Yu J, Smith C, Feng W Abstract Background and objective: Low Intensity Transcranial Ultrasound Stimulation (TUS) is a new form of non-invasive brain modulation with promising data; however, systematic reviews on the brain modulatory effects of TUS...
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Related ArticlesUse of the Test of Scientific Literacy Skills Reveals That Fundamental Literacy Is an Important Contributor to Scientific Literacy. CBE Life Sci Educ. 2019 Sep;18(3):ar31 Authors: Shaffer JF, Ferguson J, Denaro K Abstract College science courses aim to teach students both disciplinary knowledge and scientific literacy skills. Several instruments have been developed to assess students' scientific literacy skills, but few studies have reported...
Related Articles"Seeing" Data Like an Expert: An Eye-Tracking Study Using Graphical Data Representations. CBE Life Sci Educ. 2019 Sep;18(3):ar32 Authors: Harsh JA, Campillo M, Murray C, Myers C, Nguyen J, Maltese AV Abstract Given the centrality of data visualizations in communicating scientific information, increased emphasis has been placed on the development of students' graph literacy-the ability to generate and interpret data representations-to...
Related ArticlesContrasting Cases: Students' Experiences in an Active-Learning Biology Classroom. CBE Life Sci Educ. 2019 Sep;18(3):ar33 Authors: Wiltbank LB, Williams KR, Marciniak L, Momsen JL Abstract In this qualitative study, we examined the process of active learning from the perspective of undergraduate students in a high-enrollment introductory biology class. Eight students participated in a series of five interviews throughout the semester that...
Related ArticlesCan Test Anxiety Interventions Alleviate a Gender Gap in an Undergraduate STEM Course? CBE Life Sci Educ. 2019 Sep;18(3):ar35 Authors: Harris RB, Grunspan DZ, Pelch MA, Fernandes G, Ramirez G, Freeman S Abstract Gender gaps in exam scores or final grades are common in introductory college science and engineering classrooms, with women underperforming relative to men with the same admission test scores or college grade point averages....
Related ArticlesDefining and Measuring Students' Interest in Biology: An Analysis of the Biology Education Literature. CBE Life Sci Educ. 2019 Sep;18(3):ar34 Authors: Rowland AA, Knekta E, Eddy S, Corwin LA Abstract Understanding how students develop biology interests and the roles interest plays in biology contexts could help instructors and researchers to increase science, technology, engineering, and mathematics students' motivation and persistence....
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Abstract Inbreeding depression, the reduction of fitness due to mating of related individuals, is of particular conservation concern in species with small, isolated populations. Although inbreeding depression is widespread in natural populations, long‐lived species may be buffered from its effects during population declines due to long generation times, and thus are less likely to have evolved mechanisms of inbreeding avoidance than species with shorter generation times. However, empirical evidence...
Abstract Cellular energetics is thought to have played a key role in dictating all major evolutionary transitions in the history of life on Earth. However, how exactly cellular energetics and metabolism come together to shape evolutionary paths is not well understood. In particular, when an organism is evolved in different energy environments, what are the phenomenological differences in the chosen evolutionary trajectories, is a question that is not well understood. In this context, starting from...
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Related ArticlesThree-dimensional computed tomography analysis of frontoethmoidal cells: a critical evaluation of the International Frontal Sinus Anatomy Classification (IFAC). Clin Otolaryngol. 2019 Aug 09;: Authors: Gotlib T, Kołodziejczyk P, Kuźmińska M, Bobecka-Wesołowska K, Niemczyk K Abstract OBJECTIVES: Two major classifications of frontoethmoidal cells, Lee and Kuhn’ s and the IFAC (International Frontal Sinus Anatomy Classification), distinguish...
Related ArticlesClinical classification of clival chordomas for transnasal approaches. Neurosurg Rev. 2019 Aug 08;: Authors: Wang Q, Wang Y, Wang J, Wang Y Abstract Endoscopic endonasal approaches (EEAs) are ideal for most chordomas, but there is little information regarding the practical clinical classification of clival chordomas to guide surgery with EEAs. This article investigates a relatively concise and practical clinical classification system...
Related ArticlesValidation of the Maxillary Sinus Roof as a Landmark for Navigating the Pediatric Skull Base. Ann Otol Rhinol Laryngol. 2019 Aug 09;:3489419867967 Authors: Evans SS, Banks C, Richman J, Woolley A, Cho DY, Woodworth B Abstract OBJECTIVE: To define a new anatomic relationship in pediatric sinus surgery, assessing the maxillary roof as a constant safe landmark to avoid skull base injury in the pediatric population. STUDY DESIGN:...
Related ArticlesTurbinate-Specific IgE in Normal and Rhinitic Patients. Am J Rhinol Allergy. 2019 Mar;33(2):178-183 Authors: Hamizan AW, Rimmer J, Alvarado R, Sewell WA, Tatersall J, Barham HP, Kalish L, Harvey RJ Abstract BACKGROUND: Specific immunoglobulin E (sIgE) within the nasal airway is likely to be the most ideal marker of allergic status, but little is known of the normative values in asymptomatic patients and those with rhinitis. ...
Related ArticlesClinical significance of tumor-related edema of the optic tract affecting visual function in patients with sellar and suprasellar tumors. World Neurosurg. 2019 Aug 05;: Authors: Ju DG, Jeon C, Kim KH, Park KA, Hong SD, Seoul HJ, Shin HJ, Nam DH, Lee JI, Kong DS Abstract OBJECTIVE: Preoperative tumor-related edema of the optic tract (EOT) is often found along the white matter tract of the visual system. However, the relationship of EOT...
Related ArticlesTemporal myofascial segmentation for multilayer reconstruction of middle cranial fossa floor after extradural subtemporal approach to the clival and paraclival region. Head Neck. 2019 Aug 07;: Authors: Gagliardi F, Piloni M, Bailo M, Gragnaniello C, Nocera G, Boari N, Spina A, Caputy AJ, Mortini P Abstract BACKGROUND: Skull-base reconstruction represents a concern after resection of middle fossa (MF) tumors by the extradural subtemporal...
Related ArticlesHearing preservation in vestibular schwannoma surgery via retrosigmoid transmeatal approach. Acta Neurochir (Wien). 2019 Aug 07;: Authors: Matsushima K, Kohno M, Nakajima N Abstract BACKGROUND: Advances in various diagnostic and/or treatment modalities, including radiological imaging, neuromonitoring, and microsurgical techniques, have resulted in treatments of vestibular schwannomas being aimed at preserving facial and hearing functions...
Related ArticlesRepair of Tegmen Tympani Defect Presenting with Spontaneous Cerebrospinal Fluid Otorrhea Using the Middle Cranial Fossa Approach. J Int Adv Otol. 2017 Dec;13(3):430-433 Authors: Sönmez S, Şahin B, Polat B, Çomoğlu Ş, Orhan KS Abstract Spontaneous cerebrospinal fluid (CSF) otorrhea frequently occurs without temporal bone trauma, fracture, surgery, or any identifiable causes. It is usually associated with tegmen tympani defects of the...
Related ArticlesAn Effective Surgical Approach for the Management of Recurrent First Branchial Cleft Fistula with Cysts: A Case Report. J Int Adv Otol. 2017 Dec;13(3):419-421 Authors: Jang M, Dai C Abstract The goal of this case report is to describe an unusual case of recurrent first branchial cleft fistula with cysts and the effective surgical approach of complete removal with preservation of the facial nerve. A 27-year-old woman presented to our...
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Related ArticlesUse of deep learning to detect personalized spatial-frequency anomalies in EEGs of children with ADHD. J Neural Eng. 2019 Aug 09;: Authors: Chen H, Song Y, Li X Abstract Abstract Objective. Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent neurobehavioral disorders. Studies have tried to find the neural correlations of ADHD with electroencephalography (EEG). Due to the heterogeneity in the...
Related ArticlesA hierarchical sequential neural network with feature fusion for sleep staging based on EOG and RR signals. J Neural Eng. 2019 Aug 08;: Authors: Sun C, Chen C, Fan J, Li W, Zhang Y, Chen W Abstract OBJECTIVE: Currently, the automatic sleep staging methods mainly face two problems: the first problem is that although the algorithms which use electroencephalogram (EEG) signals have nice performance, acquiring EEG signals is complicated and...
Related ArticlesOptimizing optogenetic stimulation protocols in auditory corticofugal neurons based on closed-loop spike feedback. J Neural Eng. 2019 Aug 08;: Authors: Vila CH, Williamson RS, Hancock K, Polley DB Abstract Objective Optogenetics provides a means to probe functional connections between brain areas. By activating a set of presynaptic neurons and recording the activity from a downstream brain area, one can establish the sign and...
Related ArticlesPredicting individual decision-making responses based on the functional connectivity of resting-state EEG. J Neural Eng. 2019 Aug 08;: Authors: Si Y, Jiang L, Tao Q, Chen C, Li F, Jiang Y, Zhang T, Cao X, Wan F, Yao D, Xu P Abstract OBJECTIVE: Despite increasing evidence revealing the relationship between task-related brain activity and decision-making, the association between resting-state functional connectivity and decision-making...
Related ArticlesLarge 10x10 single cell grid networks of human hNT astrocytes on raised parylene-C/SiO2 substrates. J Neural Eng. 2019 Aug 08;: Authors: Li S, Simpson CM, Graham S, Unsworth CP Abstract OBJECTIVE: The 'Astrocytic Network' is an emerging research field for researchers in cell biology. Culturing astrocytes in organised networks is a novel method for permitting controlled studies and investigations into the calcium transients of such networks....
Related ArticlesBrain-computer interfaces and personhood: interdisciplinary deliberations on neural technology. J Neural Eng. 2019 Aug 08;: Authors: Sample M, Aunos M, Blain-Moraes S, Bublitz C, Chandler JA, Falk TH, Friedrich O, Groetzinger D, Jox RJ, Koegel J, McFarland DJ, Neufield V, Rodriguez-Arias D, Sattler S, Vidal F, Wolbring G, Wolkenstein A, Racine E Abstract Scientists, engineers, and healthcare professionals are currently developing a variety...
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Related ArticlesSacituzumab govitecan: breakthrough targeted therapy for triple-negative breast cancer. Expert Rev Anticancer Ther. 2019 Aug 09;: Authors: Weiss J, Glode A, Messersmith WA, Diamond JR Abstract Introduction: Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype associated with an increased risk of recurrence and cancer-related death. Unlike hormone receptor-positive or HER2-positive breast cancers, there are limited...
Related ArticlesDoes Breast Density Increase the Risk of Re-excision for Women with Breast Cancer Having Breast-Conservation Therapy? Ann Surg Oncol. 2019 Aug 08;: Authors: Walsh SM, Brennan SB, Zabor EC, Rosenberger LH, Stempel M, Lebron-Zapata L, Gemignani ML Abstract BACKGROUND: Women with dense breasts may have less-accurate preoperative evaluation of extent of disease, potentially affecting the achievement of negative margins. The goal of this study...
Related ArticlesCancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes. Breast Cancer Res. 2019 Aug 07;21(1):90 Authors: Sobral-Leite M, Salomon I, Opdam M, Kruger DT, Beelen KJ, van der Noort V, van Vlierberghe RLP, Blok EJ, Giardiello D, Sanders J, Van de Vijver K, Horlings HM, Kuppen PJK, Linn SC, Schmidt MK, Kok M Abstract INTRODUCTION: The presence of tumor-infiltrating lymphocytes (TILs)...
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Related ArticlesThe Role of Deubiquitinases in Oncovirus and Host Interactions. J Oncol. 2019;2019:2128410 Authors: Li Y, Shi F, Hu J, Xie L, Bode AM, Cao Y Abstract Infection-related cancer comprises one-sixth of the global cancer burden. Oncoviruses can directly or indirectly contribute to tumorigenesis. Ubiquitination is a dynamic and reversible posttranslational modification that participates in almost all cellular processes. Hijacking of the ubiquitin...
Related ArticlesHarmonization of proton treatment planning for head and neck cancer using pencil beam scanning: first report of the IPACS collaboration group. Acta Oncol. 2019 Aug 08;:1-11 Authors: Stock M, Gora J, Perpar A, Georg P, Lehde A, Kragl G, Hug E, Vondracek V, Kubes J, Poulova Z, Algranati C, Cianchetti M, Schwarz M, Amichetti M, Kajdrowicz T, Kopeć R, Mierzwińska G, Olko P, Skowrońska K, Sowa U, Góra E, Kisielewicz K, Sas-Korczyńska B, Skóra T, Bäck A, Gustafsson...
Related ArticlesDevelopment of an Attachable Endoscopic Nerve Stimulator for Intraoperative Neuromonitoring during Endoscopic or Robotic Thyroidectomy. Otolaryngol Head Neck Surg. 2018 03;158(3):465-468 Authors: Sung ES, Lee JC, Kim SH, Shin SC, Jung DW, Lee BJ Abstract We developed a simple attachable endoscopic nerve stimulator that can be connected to monopolar cauterization surgical instruments. This study on porcine models aimed to investigate...
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