Abstract The purpose of this study was to clarify the relationship between two types of dental prescale systems. Forty healthy subjects were asked to maximally clench for about 3 s, and the maximum occlusal force before and after cleaning was calculated using an Occluzer FPD707 for dental prescale (P1) and a bite force analyzing system for dental prescale II (P2). The maximum occlusal forces measured by P1 and P2 were compared before cleaning and after cleaning. Next, the relationship...
Thu Mar 19, 2020 02:00
Friedman Score in Relation to Compliance and Treatment Response in Nonsevere Obstructive Sleep Apnea
Nonsevere obstructive sleep apnea (OSA) is most often treated with a continuous positive airway pressure (CPAP) device or a mandibular advancement splint (MAS). However, patient compliance with these treatments is difficult to predict. Improvement in apnea-hypopnea index (AHI) is also somewhat unpredictable in MAS treatment. In this study, we investigated the association between Friedman tongue position score (Friedman score) and both treatment compliance and AHI improvement in patients with nonsevere...
Thu Mar 19, 2020 11:50
Presentation of Case. Dr. Ryan J. Sullivan: A 64-year-old man presented to this hospital for evaluation of a mass in the left frontal and left parietal lobes. Four weeks before this presentation, while residing at his home in Florida, the patient began to have clumsiness of the right upper arm, as…
Thu Mar 19, 2020 02:00
Publication date: June 2020Source: Brain and Language, Volume 205Author(s): Ine Van der Cruyssen, Robin Gerrits, Guy Vingerhoets
Thu Mar 19, 2020 19:23
Publication date: June 2020Source: Brain and Language, Volume 205Author(s): Garon Perceval, Andrew K. Martin, David A. Copland, Matti Laine, Marcus Meinzer
Thu Mar 19, 2020 19:23
Abstract Purpose To determine the morphological features of the denticulate ligament in fetal period. Methods Twelve formalin-fixed fetuses (six females and six males) with a mean gestational age of 27.0 ± 2.04 weeks (range between 25 and 32 weeks) were dissected to reveal morphological properties of the denticulate ligaments. ...
Thu Mar 19, 2020 02:00
Abstract How can we solve the paradox of false-belief understanding: if infants pass the implicit false belief task (FBT) by nonverbal behavioural responses why do they nonetheless typically fail the explicit FBT till they are 4 years old? Starting with the divide between situational and cognitive accounts of the development of false-belief understanding, we argue that we need to consider both situational and internal cognitive factors together and describe their interaction to...
Thu Mar 19, 2020 02:00
ABSTRACT On December 24, 2019, the pigment, melanoma, and photobiology research communities lost a treasure. Dr. Edward De Fabo passed away peacefully after a valiant 5‐year battle against advanced colon cancer. He was 82. He is survived by his wife of 33 years, Dr. Frances Noonan, who had also been his scientific partner. Together, they were a remarkable team, seeking and finding answers to critical scientific questions that had plagued researchers for decades.
Thu Mar 19, 2020 18:47
Polycystic ovary syndrome (PCOS) a long-known endocrinopathy and one of the most common endocrine-reproductive-metabolic disorders in women, which can lead to infertility. Although the precise etiology remains unclear, PCOS is considered as a complex genetic trait, with a high degree of heterogeneity. Besides, hormones and immune cells, including both innate and adaptive immune cells, are reportedly a cross talk in PCOS. Chronic low-grade inflammation increases autoimmune disease risk. This proinflammatory...
Thu Mar 19, 2020 12:20
Publication date: Available online 18 March 2020Source: World NeurosurgeryAuthor(s): Wonsoo Son, Dong-Hun Kang
Thu Mar 19, 2020 18:30
Publication date: Available online 14 March 2020Source: World NeurosurgeryAuthor(s): Paolo Palmisciano, Aimun AB. Jamjoom, Daniel Taylor, Danail Stoyanov, Hani J. Marcus
Thu Mar 19, 2020 18:30
Background. Immunological mechanisms play a vital role in the pathogenesis of knee osteoarthritis (KOA). Moreover, the immune phenotype is a relevant prognostic factor in various immune-related diseases. In this study, we used CIBERSORT for deconvolution of global gene expression data to define the immune cell landscape of different structures of knee in osteoarthritis. Methods and Findings. By applying CIBERSORT, we assessed the relative proportions of immune cells in 76 samples of knee cartilage,...
Thu Mar 19, 2020 17:05
Background. Lateral epicondylitis (LE) is a common elbow problem. Extracorporeal shock wave therapy (ESWT) was widely used in the treatment of LE and has been shown to relieve the pain and functional impairment (loss of grip strength) caused by tennis elbow. However, the evidence with regard to whether ESWT has better clinical efficacy over other method is not clear. The aim of the study was to compare the effectiveness of ESWT with other techniques in the treatment of LE. Methods. Literature searches...
Thu Mar 19, 2020 16:35
This study is aimed at elucidating how aspirin could systemically and simultaneously normalize nonalcoholic fatty liver disease (NAFLD) and atherosclerosis through both in vitro and in vivo studies in hyperlipidemic conditions. We evaluated the effects and mechanism of aspirin on the levels of various biomarkers related to NAFLD, atherosclerosis, and oxidative phosphorylation in cells and animals of hyperlipidemic conditions. The protein levels of biomarkers (PPARδ, AMPK, and PGC-1α) involved in...
Thu Mar 19, 2020 15:35
Purpose. The aim of this work was to compare the temperature fluctuations that occur during the development of the implant bed using three different implant systems and the impact on their value of cooling method and rotational speed of drill. Material and Methods. As a model of the human jaw due to the analogy of bone structure and hardness, pig ribs were used. Drills from three different implant systems were used in the study: Straumann® (Straumann GmbH, Basel, Switzerland), AnyRidge® (Megagen...
Thu Mar 19, 2020 15:35
This cross-sectional study examines factors associated with hypocalcemia after total thyroidectomy and explores the association between hypocalcemia, magnesium disorders, and costs of care.
Sun Mar 01, 2020 02:00
This cross-sectional study of 6147 English olderadults examines associations between concurrent multisensory impairments and aspects of well-being and mental health.
Sun Mar 01, 2020 02:00
A healthy woman in her 60s was referred for evaluation of a palatal swelling of unknown duration. She denied any pain or discomfort from the site and stated that the increasing size of the mass was what first alerted her to its presence. What is your diagnosis?
Sun Mar 01, 2020 02:00
This Viewpoint discusses significant changes that the author has experienced in the treatment of patients with thyroid cancer throughout the last 4 decades.
Sun Mar 01, 2020 02:00
A 52-year-old man with a history of asthma presented with exacerbation of long-standing dyspnea along with progressively worsening nasal congestion and dysphonia over the past 2 years. What is your diagnosis?
Sun Mar 01, 2020 02:00
This cohort study aims to develop and validate a utility scoring algorithm for a sleep apnea–specific quality-of-life instrument.
Sun Mar 01, 2020 02:00
Mission Statement:JAMA Otolaryngology–Head & Neck Surgery provides timely information for physicians and scientists concerned with diseases of the head and neck. Given the diversity of structure and function based in this anatomic region, JAMA Otolaryngology–Head & Neck Surgery publishes clinical, translational, and population health research from an array of disciplines. We place a high priority on strong study designs that accurately identify etiologies, evaluate diagnostic strategies,...
Sun Mar 01, 2020 02:00
This Viewpoint describes the benefits of value-based pricing for corticosteroid-eluting sinus stents for drug manufacturers, patients, and clinicians.
Sun Mar 01, 2020 02:00
To the Editor Valderrabano et al question the sensitivity and specificity of the Afirma gene expression classifier (GEC) from its pivotal clinical validation, and by extension, its negative predictive value (NPV). I disagree with their methodology and conclusions.
Sun Mar 01, 2020 02:00
This analysis of US Medicare data evaluates the number of balloon catheter dilations performed between 2011 and 2017, including the percentage of procedures performed by surgeons who perform high volumes of this procedure, reimbursements, and national geographic distributions.
Sun Mar 01, 2020 02:00
This case report describes a man in his 70s who presented with painless bilateral neck swelling of 1 year’s duration that had gradually grown to affect his speech, and was diagnosed with mantle cell lymphoma.
Sun Mar 01, 2020 02:00
This cohort study examines the factors that are associated with the favorable outcomes, defined as a House-Brackmann grade of II or lower, in patients treated for Bell palsy.
Sun Mar 01, 2020 02:00
This Clinical Challenge describes an exceedingly rare cause for pain in the right nostril of a 31-year-old woman.
Sun Mar 01, 2020 02:00
In the study by Kasle and colleagues in this issue of JAMA Otolaryngology–Head and Neck Surgery, the authors report that use of balloon catheter dilation of the sinuses is increasing rapidly, along with concomitant Medicare payments. The increase in payments in the study is stunning, even though it is only reflective of the Medicare population. Interestingly, this increase is driven by a relatively small proportion of otolaryngologist–head and neck surgeons. Estimates from industry colleagues suggest...
Sun Mar 01, 2020 02:00
This systematic review summarizes the literature on the impact of image-guided surgery on surgical outcomes and complications, newer applications in other endoscopic procedures, challenges associated with further study of the technique, and recent developments related to the technology.
Sun Mar 01, 2020 02:00
This case report describes a man in his 30s who presented with facial swelling, neck pain, dysphagia, and odynophagia. What is your diagnosis?
Sun Mar 01, 2020 02:00
In Reply We appreciate Dr Kloos’s interest in our work, but respectfully disagree with his conclusions. He states that our analysis supports Afirma’s validated 94% or greater negative predictive value (NPV) on the basis that only 23 of the 1071 (2.1%) Afirma gene expression classifier (GEC) benign nodules were reported as malignant on surgical pathologic analysis. However, only a total of 149 such nodules were actually resected in the postmarketing studies, yielding a false-negative rate of 15.4%...
Sun Mar 01, 2020 02:00
This systematic review analyzes published studies to identify social and clinical factors in head and neck cancer treatment in low-income and lower-middle-income countries predominantly in South Asia.
Sun Mar 01, 2020 02:00
The United States is struggling with an epidemic of opioid abuse driven in part by postoperative opioid prescribing patterns. Opioid prescribing after surgery is one of the most common methods of initial opioid exposure and places patients at risk of developing opioid dependency. In otolaryngology, 6% of the patients who are opioid-naive develop postoperative iatrogenic opioid dependency, which contributes considerably to the epidemic because approximately 16 million otolaryngology operations are...
Sun Mar 01, 2020 02:00
This cohort study examines the association of Medicaid expansions as part of the Patient Protection and Affordable Care Act (ACA) with stage at diagnosis and time to treatment initiation for patients with head and neck squamous cell carcinoma (HNSCC).
Sun Mar 01, 2020 02:00
This case series examines the safety of adjuvant intralesional cidofovir injections in patients with recurrent respiratory papillomatosis.
Sun Mar 01, 2020 02:00
In Reply We appreciate the inquiry of Arvold and McBride into the recurrence patterns and salvage treatments of the cohort presented in our study.
Sun Mar 01, 2020 02:00
The Best of 2019 editorial represents a new addition to JAMA Otolaryngology–Head and Neck Surgery. This Editorial is written by members of the editorial board and highlights select articles published in the journal over the past year. The selected articles represent the main specialty domains covered by the journal.
Sun Mar 01, 2020 02:00
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