Molecules, Vol. 25, Pages 1288: Spontaneous Hinge-Bending Motions of Angiotensin I Converting Enzyme: Role in Activation and Inhibition Molecules doi: 10.3390/molecules25061288 Authors: Thi Tuong Vy Seong-Yeong Heo Won-Kyo Jung Myunggi Yi The inhibition of human angiotensin I converting enzyme (ACE) has been regarded as a promising approach for the treatment of hypertension. Despite research attempts over many years, our understanding the mechanisms of activation and inhibition...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1290: Enhancing the Immune Response of a Nicotine Vaccine with Synthetic Small “Non-Natural” Peptides Molecules doi: 10.3390/molecules25061290 Authors: Hoang-Thanh Le Nya L. Fraleigh Jordan D. Lewicky Justin Boudreau Paul Dolinar Nitin Bhardwaj Francisco Diaz-Mitoma Sabine Montaut Sarah Fallahi Alexandrine L. Martel The addictive nature of nicotine is likely the most significant reason for the continued prevalence of tobacco smoking...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1293: Human Copper-Containing Amine Oxidases in Drug Design and Development Molecules doi: 10.3390/molecules25061293 Authors: Serhii Vakal Sirpa Jalkanen Käthe M. Dahlström Tiina A. Salminen Two members of the copper-containing amine oxidase family are physiologically important proteins: (1) Diamine oxidase (hDAO; AOC1) with a preference for diamines is involved in degradation of histamine and (2) Vascular adhesion protein-1 (hVAP-1; AOC3) with a preference...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1287: An Overview of the Potential Antineoplastic Effects of Casticin Molecules doi: 10.3390/molecules25061287 Authors: Shanaya Ramchandani Irum Naz Jong Hyun Lee Muhammad Rashid Khan Kwang Seok Ahn Cancer persists as one of the leading causes of deaths worldwide, contributing to approximately 9.6 million deaths per annum in recent years. Despite the numerous advancements in cancer treatment, there is still abundant scope to mitigate recurrence,...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1289: Effects of Propolis and Phenolic Acids on Triple-Negative Breast Cancer Cell Lines: Potential Involvement of Epigenetic Mechanisms Molecules doi: 10.3390/molecules25061289 Authors: João Henrique Maia Assumpção Agnes Alessandra Sekijima Takeda José Maurício Sforcin Cláudia Aparecida Rainho Triple-negative breast cancer is an aggressive disease frequently associated with resistance to chemotherapy. Evidence supports that small molecules showing...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1285: Bioactive Peptides from Walnut Residue Protein Molecules doi: 10.3390/molecules25061285 Authors: Xiangyang Li Manli Guo Jingtian Chi Jiangang Ma Walnut residue is a kind of high-quality plant protein resource. The bioactive peptide prepared from walnut residue has excellent health care functions such as antioxidation and antihypertensive activity, but at present, walnut residue is often regarded as waste or low value feed, fertilizer and other...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1286: 2-Methylimidazole Copper Iminodiacetates for the Adsorption of Oxygen and Catalytic Oxidation of Cyclohexane Molecules doi: 10.3390/molecules25061286 Authors: Xi Chen Dong-Li An Xin-Qi Zhan Zhao-Hui Zhou The mixed-ligand copper(II) iminodiacetates [Cu(ida)(2-mim)(H2O)2]·H2O (1), [Cu(ida)(2-mim)2]·2H2O (2), [Cu(ida)(2-mim)(H2O)]n·4.5nH2O (3), and [Cu2(ida)2(2-mim)2]n·nH2O (4) (H2ida = iminodiacetic acid,...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1283: Quinolinecarboxamides Inhibit the Replication of the Bovine Viral Diarrhea Virus by Targeting a Hot Spot for the Inhibition of Pestivirus Replication in the RNA-Dependent RNA Polymerase Molecules doi: 10.3390/molecules25061283 Authors: Simone Musiu Yunierkis Perez Castillo Alexandra Muigg Gerhard Pürstinger Pieter Leyssen Mathy Froeyen Johan Neyts Jan Paeshuyse The bovine viral diarrhea virus (BVDV), a pestivirus from the family of...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1284: Chemical Characteristics and Anticancer Activity of Essential Oil from Arnica Montana L. Rhizomes and Roots Molecules doi: 10.3390/molecules25061284 Authors: Piotr Sugier Joanna Jakubowicz-Gil Danuta Sugier Radosław Kowalski Urszula Gawlik-Dziki Barbara Kołodziej Dariusz Dziki Arnica montana L. is a medicinal plant with diverse biological activities commonly used in pharmacy and cosmetics. The attributes of A. montana are mainly related...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1282: Effects of the Morphology, Surface Modification and Application Methods of ZnO-NPs on the Growth and Biomass of Tomato Plants Molecules doi: 10.3390/molecules25061282 Authors: Eneida A. Pérez Velasco Rebeca Betancourt Galindo Luis A. Valdez Aguilar José A. González Fuentes Bertha A. Puente Urbina Samuel A. Lozano Morales Saúl Sánchez Valdés Benefits of nanotechnology in agriculture include reduced fertilizer loss, improved seed germination...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1280: Protein Engineering of a Pyridoxal-5′-Phosphate-Dependent l-Aspartate-α-Decarboxylase from Tribolium castaneum for β-Alanine Production Molecules doi: 10.3390/molecules25061280 Authors: Xin-Jun Yu Chang-Yi Huang Xiao-Dan Xu Hong Chen Miao-Jie Liang Zhe-Xian Xu Hui-Xia Xu Zhao Wang In the present study, a pyridoxal-5′-phosphate (PLP)-dependent L-aspartate-α-decarboxylase from Tribolium castaneum (TcPanD) was selected...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1281: A Targeted Approach by High Resolution Mass Spectrometry to Reveal New Compounds in Raisins Molecules doi: 10.3390/molecules25061281 Authors: Danilo Escobar-Avello Alexandra Olmo-Cunillera Julián Lozano-Castellón María Marhuenda-Muñoz Anna Vallverdú-Queralt Raisins are dried grapes mostly obtained from cultivars of Vitis vinifera L. and are extensively consumed worldwide. They are rich in bioactive compounds such as polyphenols, which are associated...
Thu Mar 12, 2020 02:00
Nanomaterials, Vol. 10, Pages 515: 0D-1D Hybrid Silicon Nanocomposite as Lithium-Ion Batteries Anodes Nanomaterials doi: 10.3390/nano10030515 Authors: Sergio Pinilla Sang-Hoon Park Kenneth Fontanez Francisco Márquez Valeria Nicolosi Carmen Morant Lithium ion batteries (LIBs) are the enabling technology for many of the societal changes that are expected to happen in the following years. Among all the challenges for which LIBs are the key, vehicle electrification is one...
Thu Mar 12, 2020 02:00
Nanomaterials, Vol. 10, Pages 514: Layered Nano-Sheets: Synthesis and Applications Nanomaterials doi: 10.3390/nano10030514 Authors: Paramsothy Extraordinary physical and chemical properties are enabled by two dimensional (2D) anisotropy and confinement effects in layered nano-sheet materials. Layered nano-sheet materials are 2D crystals possessing properties useful in applications ranging from electronics and energy storage to structural loads bearing nanocomposites. [...]
Thu Mar 12, 2020 02:00
Nanomaterials, Vol. 10, Pages 517: White Magnetic Paper with Zero Remanence Based on Electrospun Cellulose Microfibers Doped with Iron Oxide Nanoparticles Nanomaterials doi: 10.3390/nano10030517 Authors: G. Papaparaskeva M. M. Dinev T. Krasia-Christoforou R. Turcu S. A. Porav F. Balanean V. Socoliuc The preparation procedure of zero magnetic remanence superparamagnetic white paper by means of three-layer membrane configuration (sandwiched structure) is presented. The...
Thu Mar 12, 2020 02:00
Nanomaterials, Vol. 10, Pages 516: The Fate of Lipid-Coated and Uncoated Fluorescent Nanodiamonds during Cell Division in Yeast Nanomaterials doi: 10.3390/nano10030516 Authors: Aryan Morita Thamir Hamoh Felipe P. Perona Martinez Mayeul Chipaux Alina Sigaeva Charles Mignon Kiran J. van der Laan Axel Hochstetter Romana Schirhagl Fluorescent nanodiamonds are frequently used as biolabels. They have also recently been established for magnetic resonance and temperature...
Thu Mar 12, 2020 02:00
Nanomaterials, Vol. 10, Pages 518: Low-Power Flexible Organic Field-Effect Transistors with Solution-Processable Polymer-Ceramic Nanoparticle Composite Dielectrics Nanomaterials doi: 10.3390/nano10030518 Authors: Xiong Chen Hao Zhang Yu Zhang Xiangfeng Guan Zitong Zhang Dagui Chen Polymer-ceramic dielectric composites have been of great interest because they combine the processability of polymers with the desired dielectric properties of the ceramics. We fabricated a low...
Thu Mar 12, 2020 02:00
Nutrients, Vol. 12, Pages 755: Reference Values for Skeletal Muscle Mass – Current Concepts and Methodological Considerations Nutrients doi: 10.3390/nu12030755 Authors: Carina O. Walowski Wiebke Braun Michael J. Maisch Björn Jensen Sven Peine Kristina Norman Manfred J. Müller Anja Bosy-Westphal Assessment of a low skeletal muscle mass (SM) is important for diagnosis of ageing and disease-associated sarcopenia and is hindered by heterogeneous methods and terminologies...
Thu Mar 12, 2020 02:00
Nutrients, Vol. 12, Pages 753: Evaluations of the Peroxidative Susceptibilities of Cod Liver Oils by a 1H NMR Analysis Strategy: Peroxidative Resistivity of a Natural Collagenous and Biogenic Amine-Rich Fermented Product Nutrients doi: 10.3390/nu12030753 Authors: Percival Wann Zbasnik Schlegel Edgar Zhang Ampem Wilson Gresley Naughton Grootveld High-resolution 1H nuclear magnetic resonance (NMR) analysis was employed to molecularly screen the...
Thu Mar 12, 2020 02:00
Nutrients, Vol. 12, Pages 751: Dietary-Lifestyle Patterns Associated with Adiposity and Metabolic Abnormalities in Adult Men under 40 Years Old: A Cross-Sectional Study (MeDiSH Project) Nutrients doi: 10.3390/nu12030751 Authors: Marta Lonnie Lidia Wadolowska Elzbieta Bandurska-Stankiewicz The aim of this study was to examine the associations of dietary-lifestyle patterns (DLPs) with adiposity and metabolic abnormalities in adult Polish men that were under 40. The cross-sectional...
Thu Mar 12, 2020 02:00
Nutrients, Vol. 12, Pages 752: Associations between Body Appreciation and Disordered Eating in a Large Sample of Adolescents Nutrients doi: 10.3390/nu12030752 Authors: Baceviciene Jankauskiene Body appreciation is one of the main facets of a positive body image. The present study aimed to examine the psychometric properties of the Lithuanian version of the Body Appreciation Scale-2 (BAS-2-LT) and test the associations between body appreciation and disordered eating in a large sample...
Thu Mar 12, 2020 02:00
Nutrients, Vol. 12, Pages 754: Effect of Exercise Duration on Postprandial Glycaemic and Insulinaemic Responses in Adolescents Nutrients doi: 10.3390/nu12030754 Authors: Dring Cooper Williams Morris Sunderland Nevill High-intensity intermittent exercise (HIIE) is a potential intervention to manage hyperglycaemia and insulin resistance in adolescents. The aim of this study was to determine the optimum duration of HIIE to reduce postprandial glycaemic and insulinaemic...
Thu Mar 12, 2020 02:00
Nutrients, Vol. 12, Pages 749: Comparison of Omega-3 Eicosapentaenoic Acid Versus Docosahexaenoic Acid-Rich Fish Oil Supplementation on Plasma Lipids and Lipoproteins in Normolipidemic Adults Nutrients doi: 10.3390/nu12030749 Authors: Zhi-Hong Yang Marcelo Amar Maureen Sampson Amber B. Courville Alexander V. Sorokin Scott M. Gordon Angel M. Aponte Michael Stagliano Martin P. Playford Yi-Ping Fu Shanna Yang Nehal N. Mehta Alan T. Remaley Background:...
Thu Mar 12, 2020 02:00
Nutrients, Vol. 12, Pages 750: Using the Internet: Nutrition Information-Seeking Behaviours of Lay People Enrolled in a Massive Online Nutrition Course Nutrients doi: 10.3390/nu12030750 Authors: Melissa Adamski Helen Truby Karen M. Klassen Stephanie Cowan Simone Gibson People’s accessibility to nutrition information is now near universal due to internet access, and the information available varies in its scientific integrity and provider expertise. Understanding...
Thu Mar 12, 2020 02:00
Pathogens, Vol. 9, Pages 210: Listeria monocytogenes Response to Anaerobic Environments Pathogens doi: 10.3390/pathogens9030210 Authors: Brandy N. Roberts Damayanti Chakravarty J.C. Gardner Steven C. Ricke Janet R. Donaldson Listeria monocytogenes is a Gram-positive facultative anaerobic bacterium that is responsible for the disease, listeriosis. It is particularly lethal in pregnant women, the fetus, the elderly and the immunocompromised. The pathogen survives and replicates...
Thu Mar 12, 2020 02:00
Pathogens, Vol. 9, Pages 209: Comparison of Macrophage Responses to African Swine Fever Viruses Reveals that the NH/P68 Strain is Associated with Enhanced Sensitivity to Type I IFN and Cytokine Responses from Classically Activated Macrophages Pathogens doi: 10.3390/pathogens9030209 Authors: Giulia Franzoni Elisabetta Razzuoli Silvia Dei Giudici Tania Carta Grazia Galleri Susanna Zinellu Mauro Ledda Pierpaolo Angioi Paola Modesto Simon P. Graham Annalisa Oggiano...
Thu Mar 12, 2020 02:00
Pathogens, Vol. 9, Pages 208: Into the Deep (Sequence) of the Foot-and-Mouth Disease Virus Gene Pool: Bottlenecks and Adaptation during Infection in Naïve and Vaccinated Cattle Pathogens doi: 10.3390/pathogens9030208 Authors: Ian Fish Carolina Stenfeldt Rachel M. Palinski Steven J. Pauszek Jonathan Arzt Foot-and-mouth disease virus (FMDV) infects hosts as a population of closely related viruses referred to as a quasispecies. The behavior of this quasispecies has not been...
Thu Mar 12, 2020 02:00
Pharmaceutics, Vol. 12, Pages 259: An Enteric-Coated Polyelectrolyte Nanocomplex Delivers Insulin in Rat Intestinal Instillations when Combined with a Permeation Enhancer Pharmaceutics doi: 10.3390/pharmaceutics12030259 Authors: Sladek McCartney Eskander Dunne Santos-Martinez Benetti Tajber Brayden The use of nanocarriers is being researched to achieve oral peptide delivery. Insulin-associated anionic polyelectrolyte nanoparticle complexes (PECs) were formed...
Thu Mar 12, 2020 02:00
Pharmaceutics, Vol. 12, Pages 258: Reversible Cross-Linked Mixed Micelles for pH Triggered Swelling and Redox Triggered Degradation for Enhanced and Controlled Drug Release Pharmaceutics doi: 10.3390/pharmaceutics12030258 Authors: Di Xiong Liyang Wen Shiyuan Peng Jianchang Xu Lijuan Zhang Good stability and controlled drug release are important properties of polymeric micelles for drug delivery. A good candidate for drug delivery must have outstanding stability in a normal...
Thu Mar 12, 2020 02:00
Pharmaceutics, Vol. 12, Pages 255: Topical Pioglitazone Nanoformulation for the Treatment of Atopic Dermatitis: Design, Characterization and Efficacy in Hairless Mouse Model Pharmaceutics doi: 10.3390/pharmaceutics12030255 Authors: Espinoza Vera-García Silva-Abreu Domènech Badia Rodríguez-Lagunas Clares Calpena Pioglitazone (PGZ) is a drug used to treat type 2 diabetes mellitus that has been reported to show additional therapeutic activities on diverse inflammatory...
Thu Mar 12, 2020 02:00
Pharmaceutics, Vol. 12, Pages 257: In Vitro Performance of an Investigational Vibrating-Membrane Nebulizer with Surfactant under Simulated, Non-Invasive Neonatal Ventilation Conditions: Influence of Continuous Positive Airway Pressure Interface and Nebulizer Positioning on the Lung Dose Pharmaceutics doi: 10.3390/pharmaceutics12030257 Authors: Federico Bianco Elena Pasini Marcello Nutini Xabier Murgia Carolin Stoeckl Martin Schlun Uwe Hetzer Sauro Bonelli Marta Lombardini...
Thu Mar 12, 2020 02:00
Pharmaceutics, Vol. 12, Pages 256: Dendritic Cells and Immunogenic Cancer Cell Death: A Combination for Improving Antitumor Immunity Pharmaceutics doi: 10.3390/pharmaceutics12030256 Authors: María Julia Lamberti Annunziata Nigro Fátima María Mentucci Natalia Belén Rumie Vittar Vincenzo Casolaro Jessica Dal Col The safety and feasibility of dendritic cell (DC)-based immunotherapies in cancer management have been well documented after more than twenty-five years of experimentation,...
Thu Mar 12, 2020 02:00
Pharmaceutics, Vol. 12, Pages 254: Dual Peptide-Modified Nanoparticles Improve Combination Chemotherapy of Etoposide and siPIK3CA Against Drug-Resistant Small Cell Lung Carcinoma Pharmaceutics doi: 10.3390/pharmaceutics12030254 Authors: Hsin-Lin Huang Wen Jen Lin Small cell lung carcinoma (SCLC) is a highly aggressive form of malignancy with rapid recurrence and poor prognosis. The dual peptide-modified nanoparticles (NPs) for improving chemotherapy against drug-resistant small cell...
Thu Mar 12, 2020 02:00
Pharmacy, Vol. 8, Pages 40: Advancing Pharmacy Practice through an Innovative Ambulatory Care Transitions Program at an Academic Medical Center Pharmacy doi: 10.3390/pharmacy8010040 Authors: Jamie Cavanaugh Nicole Pinelli Stephen Eckel Mark Gwynne Rowell Daniels Emily M. Hawes Hospital readmissions are common and often preventable, leading to unnecessary burden on patients, families, and the health care system. The purpose of this descriptive communication is to share...
Thu Mar 12, 2020 02:00
Philosophies, Vol. 5, Pages 5: A Naturalistic Perspective on Knowledge How: Grasping Truths in a Practical Way Philosophies doi: 10.3390/philosophies5010005 Authors: Felix Stephens For quite some time, cognitive science has offered philosophy an opportunity to address central problems with an arsenal of relevant theories and empirical data. However, even among those naturalistically inclined, it has been hard to find a universally accepted way to do so. In this article, we offer...
Thu Mar 12, 2020 02:00
Plants, Vol. 9, Pages 360: Somatic Embryogenesis and Plantlet Regeneration in the Carica papaya L. cv. Eksotika Plants doi: 10.3390/plants9030360 Authors: Al-Shara Taha Mohamad Elias Khan A highly efficient protocol for regeneration of Carica papaya L. cv. Eksotika somatic embryos from immature zygotic embryos was developed. This study was designed to overcome the obstacles in regeneration of somatic embryos from immature zygotic embryos of “Eksotika”,...
Thu Mar 12, 2020 02:00
Plants, Vol. 9, Pages 359: Trends in Seaweed Extract Based Biostimulants: Manufacturing Process and Beneficial Effect on Soil-Plant Systems Plants doi: 10.3390/plants9030359 Authors: Mohammed EL Mehdi EL Boukhari Mustapha Barakate Youness Bouhia Karim Lyamlouli The time when plant biostimulants were considered as “snake oil” is erstwhile and the skepticism regarding their agricultural benefits has significantly faded, as solid scientific evidences of their...
Thu Mar 12, 2020 02:00
Plants, Vol. 9, Pages 358: Evolutionary Trends in the Mitochondrial Genome of Archaeplastida: How Does the GC Bias Affect the Transition from Water to Land? Plants doi: 10.3390/plants9030358 Authors: Joan Pedrola-Monfort David Lázaro-Gimeno Carlos G. Boluda Laia Pedrola Alfonso Garmendia Carla Soler Jose M. Soriano Among the most intriguing mysteries in the evolutionary biology of photosynthetic organisms are the genesis and consequences of the dramatic increase in...
Thu Mar 12, 2020 02:00
Religions, Vol. 11, Pages 124: Love me for the Sake of the World: “Goddess Songs” in Tantric Buddhist Maṇḍala Rituals Religions doi: 10.3390/rel11030124 Authors: Stephenson The presence of Apabhraṃśa in tantric Buddhist texts has long been noted by scholars, overwhelmingly explained away as an example of “Twilight language” (saṃdhā-bhāṣā). However, when one looks closer at the vast number of Apabhraṃśa verses in this canon, one finds recurring patterns, themes, and...
Thu Mar 12, 2020 02:00
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