JCM, Vol. 9, Pages 768: To Treat or Not to Treat: Importance of Functional Dependence in Deciding Intravenous Thrombolysis of “Mild Stroke” Patients Journal of Clinical Medicine doi: 10.3390/jcm9030768 Authors: Giovanni Merlino Carmelo Smeralda Simone Lorenzut Gian Luigi Gigli Andrea Surcinelli Mariarosaria Valente Intravenous thrombolysis (IVT) in patients with a low National Institutes of Health Stroke Scale (NIHSS) score of 0–5 remains controversial. IVT should...
Thu Mar 12, 2020 02:00
JCM, Vol. 9, Pages 771: Therapeutic Potential of Proanthocyanidins in Ulcerative Colitis in Remission Journal of Clinical Medicine doi: 10.3390/jcm9030771 Authors: Dominika Głąbska Dominika Guzek Karolina Gałązka Gustaw Lech A number of bioactive components of diet are indicated as potential dietary factors for the management of ulcerative colitis, while the recent study conducted in an animal model revealed that proanthocyanidins from grape seeds exert a broadly positive impact....
Thu Mar 12, 2020 02:00
JCM, Vol. 9, Pages 766: Application of Adult and Pluripotent Stem Cells in Interstitial Cystitis/Bladder Pain Syndrome Therapy: Methods and Perspectives Journal of Clinical Medicine doi: 10.3390/jcm9030766 Authors: Ahmed Abdal Dayem Kyeongseok Kim Soo Bin Lee Aram Kim Ssang-Goo Cho Interstitial cystitis/bladder pain syndrome (IC/BPS) is a multifactorial, chronic disease without definite etiology characterized by bladder-related pelvic pain. IC/BPS is associated with pain...
Thu Mar 12, 2020 02:00
JCM, Vol. 9, Pages 773: Serum Uric Acid is Associated with Renal Prognosis of Lupus Nephritis in Women but not in Men Journal of Clinical Medicine doi: 10.3390/jcm9030773 Authors: Tae Ryom Oh Hong Sang Choi Chang Seong Kim Dong-Ryeol Ryu Sun-Hee Park Shin Young Ahn Soo Wan Kim Eun Hui Bae Seong Kwon Ma Lupus nephritis (LN) is a major complication of systemic lupus erythematosus. Early intervention in lupus nephritis improves prognosis. There is an association...
Thu Mar 12, 2020 02:00
JCM, Vol. 9, Pages 765: Metabolic Alterations Associated with Early-Stage Hepatocellular Carcinoma and Their Correlation with Aging and Enzymatic Activity in Patients with Viral Hepatitis-Induced Liver Cirrhosis: A Preliminary Study Journal of Clinical Medicine doi: 10.3390/jcm9030765 Authors: Chung-Man Moon Sang Soo Shin Suk Hee Heo Yong Yeon Jeong Liver cirrhosis (LC) can develop hepatocellular carcinoma (HCC). However, noninvasive early diagnosis of HCCs in the cirrhotic...
Thu Mar 12, 2020 02:00
JCM, Vol. 9, Pages 764: Transradial and Transfemoral Approach in Patients with Prior Coronary Artery Bypass Grafting Journal of Clinical Medicine doi: 10.3390/jcm9030764 Authors: Rafał Januszek Zbigniew Siudak Krzysztof Piotr Malinowski Wojciech Wańha Wojciech Wojakowski Mariusz Gąsior Stanisław Bartuś Dariusz Dudek The relationship between periprocedural complications and the type of vascular access in patients with prior history of coronary artery bypass grafting...
Thu Mar 12, 2020 02:00
JCM, Vol. 9, Pages 763: Strengths and Weaknesses of Light Transmission Aggregometry in Diagnosing Hereditary Platelet Function Disorders Journal of Clinical Medicine doi: 10.3390/jcm9030763 Authors: Marie-Christine Alessi Pierre Sié Bernard Payrastre Hereditary defects in platelet function are responsible for sometimes severe mucocutaneous hemorrhages. They are a heterogeneous group of abnormalities whose first-line diagnosis typically involves interpreting the results of in vitro...
Thu Mar 12, 2020 02:00
Life, Vol. 10, Pages 24: Is the Application of Plant Probiotic Bacterial Consortia Always Beneficial for Plants? Exploring Synergies between Rhizobial and Non-Rhizobial Bacteria and Their Effects on Agro-Economically Valuable Crops Life doi: 10.3390/life10030024 Authors: Esther Menéndez Ana Paço The overgrowth of human population and the demand for high-quality foods necessitate the search for sustainable alternatives to increase crop production. The use of biofertilizers, mostly...
Thu Mar 12, 2020 02:00
Medicina, Vol. 56, Pages 123: Perish or Publish Dilemma: Challenges to Responsible Authorship Medicina doi: 10.3390/medicina56030123 Authors: Aliukonis Poškutė Gefenas Controversies related to the concept and practice of responsible authorship and its misuse have been among the most prominent issues discussed in the recent literature on research integrity. Therefore, this paper aims to address the factors that lead to two major types of unethical authorship, namely, honorary...
Thu Mar 12, 2020 02:00
Medicina, Vol. 56, Pages 122: A Prospective Intervention Trial on Tailored Radiofrequency Ablation of Uterine Myomas Medicina doi: 10.3390/medicina56030122 Authors: Alessandro Fasciani Giovanni Turtulici Giacomo Siri Simone Ferrero Rodolfo Sirito Background and Objective: Investigating the use of radiofrequency myolysis (RFM) for the treatment of fibroids through less invasive access by combining transvaginal ultrasound, hysteroscopy and laparoscopy. Materials and Methods:...
Thu Mar 12, 2020 02:00
Medicines, Vol. 7, Pages 13: High Serum Phosphate Level as a Risk Factor to Determine Renal Prognosis in Autosomal Dominant Polycystic Kidney Disease: A Retrospective Study Medicines doi: 10.3390/medicines7030013 Authors: Masayo Sato Hiroshi Kataoka Yusuke Ushio Shun Manabe Saki Watanabe Taro Akihisa Shiho Makabe Rie Yoshida Naomi Iwasa Michihiro Mitobe Norio Hanafusa Ken Tsuchiya Kosaku Nitta Toshio Mochizuki Background: Serum phosphate levels,...
Thu Mar 12, 2020 02:00
Membranes, Vol. 10, Pages 42: Using Additives for Fouling Control in a Lab-Scale MBR; Comparing the Anti-Fouling Potential of Coagulants, PAC and Bio-Film Carriers Membranes doi: 10.3390/membranes10030042 Authors: Gkotsis Zouboulis Mitrakas This study investigates the effect of different additives, such as coagulants/flocculants, adsorption agents (powdered activated carbon, PAC), and bio-film carriers, on the fouling propensity of a lab-scale membrane bio-reactor (MBR) treating...
Thu Mar 12, 2020 02:00
Membranes, Vol. 10, Pages 43: Measurement of Multi Ion Transport through Human Bronchial Epithelial Cell Line Provides an Insight into the Mechanism of Defective Water Transport in Cystic Fibrosis Membranes doi: 10.3390/membranes10030043 Authors: Zajac Lewenstam Bednarczyk Dolowy We measured concentration changes of sodium, potassium, chloride ions, pH and the transepithelial potential difference by means of ion-selective electrodes, which were placed on both sides of a...
Thu Mar 12, 2020 02:00
Metabolites, Vol. 10, Pages 105: Intracellular Metabolites in Marine Microorganisms during an Experiment Evaluating Microbial Mortality Metabolites doi: 10.3390/metabo10030105 Authors: Longnecker Kujawinski Metabolomics is a tool with immense potential for providing insight into the impact of biological processes on the environment. Here, we used metabolomics methods to characterize intracellular metabolites within marine microorganisms during a manipulation experiment that was...
Thu Mar 12, 2020 02:00
Metabolites, Vol. 10, Pages 106: Antifungal Drugs Metabolites doi: 10.3390/metabo10030106 Authors: Houšť Spížek Havlíček We reviewed the licensed antifungal drugs and summarized their mechanisms of action, pharmacological profiles, and susceptibility to specific fungi. Approved antimycotics inhibit 1,3-β-d-glucan synthase, lanosterol 14-α-demethylase, protein, and deoxyribonucleic acid biosynthesis, or sequestrate ergosterol. Their most severe side effects...
Thu Mar 12, 2020 02:00
Metabolites, Vol. 10, Pages 104: Important Considerations for Sample Collection in Metabolomics Studies with a Special Focus on Applications to Liver Functions Metabolites doi: 10.3390/metabo10030104 Authors: Lorraine Smith Joran Villaret-Cazadamont Sandrine P. Claus Cécile Canlet Hervé Guillou Nicolas J. Cabaton Sandrine Ellero-Simatos Metabolomics has found numerous applications in the study of liver metabolism in health and disease. Metabolomics studies can be conducted...
Thu Mar 12, 2020 02:00
Metabolites, Vol. 10, Pages 103: Simultaneous Measurement of Tricarboxylic Acid Cycle Intermediates in Different Biological Matrices Using Liquid Chromatography–Tandem Mass Spectrometry; Quantitation and Comparison of TCA Cycle Intermediates in Human Serum, Plasma, Kasumi-1 Cell and Murine Liver Tissue Metabolites doi: 10.3390/metabo10030103 Authors: Ramji Rathod Bharat Gajera Kenneth Nazir Janne Wallenius Vidya Velagapudi The tricarboxylic acid (TCA) cycle is a central part...
Thu Mar 12, 2020 02:00
Metabolites, Vol. 10, Pages 102: Evaluation of the Potential Allergenicity of Strawberries in Response to Different Farming Practices Metabolites doi: 10.3390/metabo10030102 Authors: Mateusz Aninowski Renata Kazimierczak Ewelina Hallmann Joanna Rachtan-Janicka Elżbieta Fijoł-Adach Beata Feledyn-Szewczyk Iwona Majak Joanna Leszczyńska Fruit allergies are a large problem today. Many consumers suffer from food allergies or intolerances. The method of food production...
Thu Mar 12, 2020 02:00
MPs, Vol. 3, Pages 22: Uncovering Effects from the Structure of Metabarcode Sequences for Metagenetic and Microbiome Analysis Methods and Protocols doi: 10.3390/mps3010022 Authors: David C. Molik Michael E. Pfrender Scott J. Emrich The advent of next-generation sequencing has allowed for higher-throughput determination of which species live within a specific location. Here we establish that three analysis methods for estimating diversity within samples—namely, Operational...
Thu Mar 12, 2020 02:00
Microorganisms, Vol. 8, Pages 399: A Case of Aeromonas trota in an Immunocompromised Patient with Diarrhea. Microorganisms doi: 10.3390/microorganisms8030399 Authors: Fernández-Bravo Fort-Gallifa Ballester Pujol Gomez-Bertomeu Domínguez Micó Alcoceba Simó-Sisó Figueras According to recent literature, 95.4% of the Aeromonas strains associated with human clinical cases correspond to four species: Aeromonas caviae, Aeromonas dhakensis, Aeromonas veronii...
Thu Mar 12, 2020 02:00
Microorganisms, Vol. 8, Pages 400: Application of a Novel Phage LPSEYT for Biological Control of Salmonella in Foods Microorganisms doi: 10.3390/microorganisms8030400 Authors: Yan Liang Yin Zhou Sharoba Lu Dong Liu Connerton Li Salmonella is a leading cause of foodborne diseases, and in recent years, many isolates have exhibited a high level of antibiotic resistance, which has led to huge pressures on public health. Phages are a promising strategy...
Thu Mar 12, 2020 02:00
Microorganisms, Vol. 8, Pages 398: Potential Effects of Indole-3-Lactic Acid, a Metabolite of Human Bifidobacteria, on NGF-induced Neurite Outgrowth in PC12 Cells Microorganisms doi: 10.3390/microorganisms8030398 Authors: Wong Tanaka Kuhara Xiao Gut microbiota-derived tryptophan metabolites such as indole derivatives are an integral part of host metabolome that could mediate gut–brain communication and contribute to host homeostasis. We previously reported that...
Thu Mar 12, 2020 02:00
Microorganisms, Vol. 8, Pages 397: Long-Term Surveillance of Antibiotic Prescriptions and the Prevalence of Antimicrobial Resistance in Non-Fermenting Gram-Negative Bacilli Microorganisms doi: 10.3390/microorganisms8030397 Authors: Chia-Huei Chou Yi-Ru Lai Chih-Yu Chi Mao-Wang Ho Chao-Ling Chen Wei-Chih Liao Cheng-Mao Ho Yu-An Chen Chih-Yu Chen Yu-Tzu Lin Chia-Der Lin Chih-Ho Lai The increasing emergence of multidrug-resistant (MDR) bacteria has been...
Thu Mar 12, 2020 02:00
Microorganisms, Vol. 8, Pages 396: Niche Partitioning with Temperature among Heterocystous Cyanobacteria (Scytonema spp., Nostoc spp., and Tolypothrix spp.) from Biological Soil Crusts Microorganisms doi: 10.3390/microorganisms8030396 Authors: Ana Giraldo-Silva Vanessa M. C. Fernandes Julie Bethany Ferran Garcia-Pichel Heterocystous cyanobacteria of biocrusts are key players for biological fixation in drylands, where nitrogen is only second to water as a limiting resource. We...
Thu Mar 12, 2020 02:00
Microorganisms, Vol. 8, Pages 395: Heat Shock Protein DnaJ in Pseudomonas aeruginosa Affects Biofilm Formation via Pyocyanin Production Microorganisms doi: 10.3390/microorganisms8030395 Authors: Bo Zeng Chong Wang Pansong Zhang Zisheng Guo Lin Chen Kangmin Duan Heat shock proteins (HSPs) play important biological roles, and they are implicated in bacterial response to environmental stresses and in pathogenesis of infection. The role of HSPs in P. aeruginosa, however, remains...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1300: Antileukemic Cell Proliferation of Active Compounds from Kaffir Lime (Citrus hystrix) Leaves Molecules doi: 10.3390/molecules25061300 Authors: Songyot Anuchapreeda Fah Chueahongthong Natsima Viriyaadhammaa Pawaret Panyajai Riki Anzawa Singkome Tima Chadarat Ampasavate Aroonchai Saiai Methee Rungrojsakul Toyonobu Usuki Siriporn Okonogi Kaffir lime (Citrus hystrix) is a plant member of family Rutaceae, and its leaves are commonly...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1304: PETRA: Drug Engineering via Rigidity Analysis Molecules doi: 10.3390/molecules25061304 Authors: Sam Herr Josh Myers-Dean Hunter Read Filip Jagodzinski Rational drug design aims to develop pharmaceutical agents that impart maximal therapeutic benefits via their interaction with their intended biological targets. In the past several decades, advances in computational tools that inform wet-lab techniques have aided the development of a wide variety...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1303: Chemical Compositions, Mosquito Larvicidal and Antimicrobial Activities of Essential Oils from Five Species of Cinnamomum Growing Wild in North Central Vietnam Molecules doi: 10.3390/molecules25061303 Authors: Dai Chung Huong Hung Chau Yen Setzer Members of the genus Cinnamomum (Lauraceae) have aromatic volatiles in their leaves and bark and some species are commercially important herbs and spices. In this work, the essential oils...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1302: Treatment with Subcritical Water-Hydrolyzed Citrus Pectin Ameliorated Cyclophosphamide-Induced Immunosuppression and Modulated Gut Microbiota Composition in ICR Mice Molecules doi: 10.3390/molecules25061302 Authors: Chen Zhang Xia Liu Tan Li Cao Subcritical water can effectively hydrolyze pectin into smaller molecules while still maintaining its functional regions. Pectic heteropolysaccharide can mediate immune regulation; however,...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1301: Effect of Multiplicity Fluctuation in Cobalt Ions on Crystal Structure, Magnetic and Electrical Properties of NdCoO3 and SmCoO3 Molecules doi: 10.3390/molecules25061301 Authors: Dudnikov Orlov Solovyov Vereshchagin Gavrilkin Tsvetkov Velikanov Gorev Novikov Ovchinnikov The structural, magnetic, electrical, and dilatation properties of the rare-earth NdCoO3 and SmCoO3 cobaltites were investigated. Their comparative analysis...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1305: Psoralen Derivatives as Inhibitors of Mycobacterium tuberculosis Proteasome Molecules doi: 10.3390/molecules25061305 Authors: Rožman Alexander Ogorevc Bozovičar Sosič Aldrich Gobec Protein degradation is a fundamental process in all living organisms. An important part of this system is a multisubunit, barrel-shaped protease complex called the proteasome. This enzyme is directly responsible for the proteolysis of ubiquitin- or pup-tagged...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1299: Antidepressant Potential of Lotus corniculatus L. subsp. corniculatus: An Ethnobotany Based Approach Molecules doi: 10.3390/molecules25061299 Authors: Fatma Tuğçe Gürağaç Dereli Haroon Khan Eduardo Sobarzo-Sánchez Esra Küpeli Akkol As a Turkish traditional medicinal plant, aerial parts of Lotus corniculatus L. subsp. corniculatus (Fabaceae) are used as a painkiller, antihemoroidal, diuretic and sedative. In this study, the antidepressant potential...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1297: Zinc Binding to Fulvic Acids: Assessing the Impact of pH, Metal Concentrations and Chemical Properties of Fulvic Acids on the Mechanism and Stability of Formed Soluble Complexes Molecules doi: 10.3390/molecules25061297 Authors: Patrycja Boguta Zofia Sokołowska The aim of the study was defined as a complementary analysis of molecular interactions between zinc (Zn) and fulvic acids (FAs) at a broad pH range (3–7), different metal concentrations...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1296: PNA-Based MicroRNA Detection Methodologies Molecules doi: 10.3390/molecules25061296 Authors: Enrico Cadoni Alex Manicardi Annemieke Madder MicroRNAs (miRNAs or miRs) are small noncoding RNAs involved in the fine regulation of post-transcriptional processes in the cell. The physiological levels of these short (20–22-mer) oligonucleotides are important for the homeostasis of the organism, and therefore dysregulation can lead to the onset...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1291: Recent Bio-Advances in Metal-Organic Frameworks Molecules doi: 10.3390/molecules25061291 Authors: Isobel Tibbetts George E. Kostakis Metal-organic frameworks (MOFs) have found uses in adsorption, catalysis, gas storage and other industrial applications. Metal Biomolecule Frameworks (bioMOFs) represent an overlap between inorganic, material and medicinal sciences, utilising the porous frameworks for biologically relevant purposes. This review details...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1295: Graphene Aerogel Growth on Functionalized Carbon Fibers Molecules doi: 10.3390/molecules25061295 Authors: Katerina Vrettos Konstantinos Spyrou Vasilios Georgakilas Graphene aerogel (GA) is a lightweight, porous, environmentally friendly, 3D structured material with interesting properties, such as electrical conductivity, a high surface area, and chemical stability, which make it a powerful tool in energy storage, sensing, catalyst support, or environmental...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1294: Thermally-Induced Lactosylation of Whey Proteins: Identification and Synthesis of Lactosylated β-lactoglobulin Epitope Molecules doi: 10.3390/molecules25061294 Authors: Alessandra Gasparini Sofie Buhler Andrea Faccini Stefano Sforza Tullia Tedeschi The high temperatures used in the production of milk may induce modifications in proteins structure. Due to occurrence of the Maillard reaction, lactose binds lysine residues in proteins, affecting...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1298: Crosslinked Nanocomposite Sodium Alginate-Based Membranes with Titanium Dioxide for the Dehydration of Isopropanol by Pervaporation Molecules doi: 10.3390/molecules25061298 Authors: Premakshi H. G. Mahadevappa Y. Kariduraganavar Geoffrey R. Mitchell Sodium alginate (NaAlg) based membranes were prepared using a solution technique, crosslinked with poly(styrene sulfonic acid-co-maleic acid) (PSSA-co-MA). Subsequently, the membranes were modified by...
Thu Mar 12, 2020 02:00
Molecules, Vol. 25, Pages 1292: QSPR/QSAR: State-of-Art, Weirdness, the Future Molecules doi: 10.3390/molecules25061292 Authors: Andrey A. Toropov Alla P. Toropova Ability of quantitative structure–property/activity relationships (QSPRs/QSARs) to serve for epistemological processes in natural sciences is discussed. Some weirdness of QSPR/QSAR state-of-art is listed. There are some contradictions in the research results in this area. Sometimes, these should be classified...
Thu Mar 12, 2020 02:00
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