Related ArticlesLongitudinal effects of a novel advanced pneumatic compression device on patient-reported outcomes in the management of cancer-related head and neck lymphedema: A preliminary report. Head Neck. 2020 Mar 18;: Authors: Gutiérrez C, Mayrovitz HN, Naqvi SHS, Karni RJ Abstract BACKGROUND: Head and neck cancer (HNC) survivors experience head and neck lymphedema (HNL), which requires treatment to prevent morbidity. We explore the self-reported...
Thu Mar 19, 2020 13:53
Related ArticlesNatural history of recurrent pleomorphic adenoma: implications on management. Head Neck. 2020 Mar 18;: Authors: Valstar MH, Andreasen S, Bhairosing PA, McGurk M Abstract BACKGROUND: Treating recurrent pleomorphic adenoma (RPA) aims to reduce risk of malignant transformation (MT) while avoiding facial nerve injury. Our objective was to systematically investigate this natural history of RPA and address the current rational for its treatment....
Thu Mar 19, 2020 13:53
Related ArticlesPrevalence, clinical course, and predictive factors of immune checkpoint inhibitor monotherapy-associated hepatitis in Japan. J Gastroenterol Hepatol. 2020 Mar 18;: Authors: Kitagataya T, Suda G, Nagashima K, Katsurada T, Yamamoto K, Kimura M, Maehara O, Yamada R, Shigesawa T, Suzuki K, Nakamura A, Ohara M, Umemura M, Kawagishi N, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Ohnishi S, Komatsu Y, Hata H, Takeuchi S, Abe T, Sakakibara-Konishi J,...
Thu Mar 19, 2020 13:53
Related ArticlesImpact of the Patient Protection and Affordable Care Act on cost-related medication underuse in nonelderly adult cancer survivors. Cancer. 2020 Mar 18;: Authors: Barnes JM, Johnson KJ, Adjei Boakye E, Sethi RKV, Varvares MA, Osazuwa-Peters N Abstract BACKGROUND: Cost-related medication underuse (CRMU), a measure of access to care and financial burden, is prevalent among cancer survivors. The authors quantified the impact of the Patient...
Thu Mar 19, 2020 13:53
Related ArticlesSymptoms of central nervous system oxygen toxicity during 100% oxygen breathing at normobaric pressure with increasing inspired levels of carbon dioxide: a case report. Diving Hyperb Med. 2020 Mar 31;50(1):70-74 Authors: Eynan M, Arieli Y, Taran B, Yanir Y Abstract The greatest danger faced by divers who use oxygen-enriched gas mixtures is central nervous system oxygen toxicity (CNS-OT). CNS-OT is characterised by convulsions resembling...
Thu Mar 19, 2020 13:53
Related ArticlesSphenoid Sinus Giant Cell Tumor: A Case Report and Literature Review. ORL J Otorhinolaryngol Relat Spec. 2020 Mar 18;:1-6 Authors: Pousti BT, Andera L, Haugen TW Abstract We describe a 27-year-old female with a giant cell tumor of her sphenoid sinus, presenting with nasal obstruction and cranial neuropathies. Both the surgical and subsequent medical management are reviewed. Additionally, we review the overall presentation, pathophysiology,...
Thu Mar 19, 2020 13:53
Related ArticlesThe genomic landscape of metastatic papillary thyroid carcinoma and novel biomarkers for predicting distant metastasis. Cancer Sci. 2020 Mar 18;: Authors: Lan X, Bao H, Ge X, Cao J, Fan X, Zhang Q, Liu K, Zhang X, Tan Z, Zheng C, Wang A, Chen C, Zhu X, Wang J, Xu J, Zhu X, Wu X, Wang X, Shao Y, Ge M Abstract Papillary thyroid carcinoma (PTC) is the most common malignancy of the thyroid gland with a relatively high cure rate. Distant...
Thu Mar 19, 2020 13:53
Related ArticlesPrevalence of respiratory symptoms and spirometric changes among non-smoker male wood workers. PLoS One. 2020;15(3):e0224860 Authors: K Hosseini D, Malekshahi Nejad V, Sun H, K Hosseini H, Adeli SH, Wang T Abstract OBJECTIVE: To assess the effects of workplace exposure to hardwood dust on lung function and determine a prevalence of respiratory symptoms among wood workers. STUDY DESIGN: Cross-sectional observational study....
Thu Mar 19, 2020 13:53
Related ArticlesFluoro-deoxy-glucose uptake in the mylohyoid muscle: a common misconception. Nucl Med Commun. 2020 Mar 13;: Authors: Pizzuto DA, Husmann L, Stolzmann P, Meerwein C, Orita E, von Schulthess GK, Huellner MW Abstract AIM: The mylohyoid muscle is often believed to exhibit high physiologic fluoro-deoxy-glucose (FDG) uptake. Aim of this study was to use PET/MR for adequately assessing the normal FDG distribution in floor of the mouth (FOM)...
Thu Mar 19, 2020 13:53
Related ArticlesLong non‑coding RNA EBLN3P promotes the recovery of the function of impaired spiral ganglion neurons by competitively binding to miR‑204‑5p and regulating TMPRSS3 expression. Int J Mol Med. 2020 Mar 17;: Authors: Jiang W, Peng A, Chen Y, Pang B, Zhang Z Abstract Sensorineural hearing loss (SNHL) is one of the major leading causes of hearing impairment, and is typically characterized by the degeneration of spiral ganglion neurons (SGNs)....
Thu Mar 19, 2020 13:53
Related ArticlesA Prospective Randomized Clinical Trial of Combination Therapy with Proton Pump Inhibitors and Mucolytics in Patients with Laryngopharyngeal Reflux. Ann Otol Rhinol Laryngol. 2020 Mar 18;:3489420913592 Authors: Chae M, Jang DH, Kim HC, Kwon M Abstract OBJECTIVES: To identify whether combination therapy with mucolytics and proton pump inhibitors (PPIs) leads to faster and more effective symptomatic relief in patients with laryngopharyngeal...
Thu Mar 19, 2020 13:53
Head and neck sarcomas: the first report addressing the duration of symptoms and diagnostic work up.
Related ArticlesHead and neck sarcomas: the first report addressing the duration of symptoms and diagnostic work up. Acta Otolaryngol. 2020 Mar 18;:1-5 Authors: Aalling M, Klug TE, Ovesen T Abstract Background: Head and neck sarcomas are rare and difficult to diagnose and manage.Aim: To describe a population of patients with head and neck sarcomas focusing on the effect of symptom duration and time to diagnosis on mortality and recurrence risk.Materials...
Thu Mar 19, 2020 13:53
Related ArticlesDouble-blind randomized controlled trial on efficacy of cupulolith repositioning maneuver for treatment of apogeotropic horizontal canal benign paroxysmal positional vertigo. Acta Otolaryngol. 2020 Mar 18;:1-6 Authors: Kong TH, Song MH, Kang JW, Shim DB Abstract Backgrounds: Although various therapeutic maneuvers have been proposed, it is still unclear which maneuver is better to treat apogeotropic horizontal canal benign paroxysmal...
Thu Mar 19, 2020 13:53
Related ArticlesEGFR cut-off point for prognostic impact in laryngeal squamous cell carcinoma. Acta Otolaryngol. 2020 Mar 18;:1-5 Authors: Leesutipornchai T, Ratchataswan T, Vivatvakin S, Ruangritchankul K, Keelawat S, Kerekhanjanarong V, Bongsebandhu-Phubhakdi S, Mahattanasakul P Abstract Background: Various molecular biomarkers, including epidermal growth factor receptor (EGFR), have gained importance as predictors of head and neck cancer disease...
Thu Mar 19, 2020 13:53
Related ArticlesNeoadjuvant chemotherapy as a comprehensive treatment in patients with laryngeal and hypopharyngeal carcinoma. Acta Otolaryngol. 2020 Mar 18;:1-7 Authors: Wei XF, Srivastava A, Lin P, Li L, Zhang S, Peng X, Liu C, Liu L, Wu LR, Li GJ, Li YC Abstract Background: Neoadjuvant chemotherapy is important for advanced laryngeal and hypopharyngeal carcinoma (LHC).Aims/objectives: To determine the efficacy and toxicity of the combination of...
Thu Mar 19, 2020 13:53
Related ArticlesAnalysis of the developmental trajectory and influencing factors of auditory and speech functions after cochlear implantation in Mandarin Chinese speaking children. Acta Otolaryngol. 2020 Mar 18;:1-8 Authors: Fan X, Sui R, Qi X, Yang X, Wang N, Hou L, Wang Z, Xu A Abstract Background: The auditory and speech development of the children with cochlear implants (CIs) are influenced by many factors.Objective: To study the developmental...
Thu Mar 19, 2020 13:53
Related ArticlesSpatiotemporal Changes in Checkpoint Molecule Expression. Adv Exp Med Biol. 2020;1248:167-200 Authors: Li W, Qie J, Zhang Y, Chang J Abstract Immune checkpoint inhibitors (ICIs), particularly PD-1/PD-L1 blockade, have led to therapeutic breakthrough in patients with advanced malignancy, covering the lung, breast, gastrointestinal, head and neck, urinary system, lymphoma, and solid tumor harboring MSI/dMMR. In certain cancer types,...
Thu Mar 19, 2020 12:23
Related ArticlesASO Author Reflections: Characteristics of Papillary Thyroid Cancer of Thyroid Isthmus and Clinical Implications of Its Extrathyroidal Extension. Ann Surg Oncol. 2020 Mar 17;: Authors: Seok J, Jeong WJ PMID: 32185538 [PubMed - as supplied by publisher]
Thu Mar 19, 2020 12:23
Related ArticlesSurgical complications of cochlear implantation: a 25-year retrospective analysis of cases in a tertiary academic center. Eur Arch Otorhinolaryngol. 2020 Mar 17;: Authors: Binnetoglu A, Demir B, Batman C Abstract PURPOSE: Despite the advances made in cochlear implantation techniques, the associated complication rates are still high. Here, we aimed to analyze cases, with extensive follow-up data, associated with a large sample of patients...
Thu Mar 19, 2020 12:23
Related Articles[91st Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery in Berlin : What quality makes the difference?] HNO. 2020 Mar 17;: Authors: Dietz A PMID: 32185425 [PubMed - as supplied by publisher]
Thu Mar 19, 2020 12:23
Related ArticlesEvone® Flow-Controlled Ventilation During Upper Airway Surgery: A Clinical Feasibility Study and Safety Assessment. Front Surg. 2020;7:6 Authors: Meulemans J, Jans A, Vermeulen K, Vandommele J, Delaere P, Vander Poorten V Abstract Introduction: During upper airway surgery in a narrowed airway due to tumor or stenosis, safe ventilation, good laryngotracheal exposure, and preservation of an adequate surgical working space are of paramount...
Thu Mar 19, 2020 12:23
Related ArticlesCurrent Understanding of the Mechanisms Underlying Immune Evasion From PD-1/PD-L1 Immune Checkpoint Blockade in Head and Neck Cancer. Front Oncol. 2020;10:268 Authors: Kok VC Abstract Starting in 2014, large phase III clinical trials began to disclose the study results of using programmed death (PD)-1 immune checkpoint inhibitors (ICIs) (pembrolizumab, nivolumab) and PD-ligand (L)1 (atezolizumab, durvalumab, avelumab) ICIs immunotherapy...
Thu Mar 19, 2020 12:23
Related ArticlesPerivascular epithelioid cell tumor (PEComa) of the pterygopalatine fossa. Clin Case Rep. 2020 Mar;8(3):553-558 Authors: Dougherty MI, Payne SC, Gupta A, Mattos JL Abstract Perivascular epithelioid cell tumors (PEComas) are a rare group of mesenchymal tumors associated with tuberous sclerosis. These tumors are typically treated with resection and rarely recur or exhibit malignant behavior. A 78-year-old woman presented with an incidentally...
Thu Mar 19, 2020 12:23
Related ArticlesA Compartmentalized Reduction in Membrane-Proximal Calmodulin Reduces the Immune Surveillance Capabilities of CD8+ T Cells in Head and Neck Cancer. Front Pharmacol. 2020;11:143 Authors: Chimote AA, Gawali VS, Newton HS, Wise-Draper TM, Conforti L Abstract The limited ability of cytotoxic CD8+ T cells to infiltrate solid tumors and function within the tumor microenvironment presents a major roadblock to effective immunotherapy. Ion...
Thu Mar 19, 2020 12:23
Related ArticlesTIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition. Onco Targets Ther. 2020;13:1993-2006 Authors: Xiao Y, Qing J, Li B, Chen L, Nong S, Yang W, Tang X, Chen Z Abstract Background: T-cell immunoglobulin and mucin domain-containing molecule-3 (TIM-3) was originally found to negatively regulate immune response and mediate immune escape in...
Thu Mar 19, 2020 12:23
Related ArticlesPhase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol. BMJ Open. 2020 Mar 16;10(3):e033009 Authors: Kong A, Good J, Kirkham A, Savage J, Mant R, Llewellyn L, Parish J, Spruce R, Forster M, Schipani S, Harrington K, Sacco J, Murray P, Middleton G, Yap C, Mehanna H Abstract INTRODUCTION:...
Thu Mar 19, 2020 12:23
Hearing loss and hearing needs in an adult homeless population: a prospective cross-sectional study.
Related ArticlesHearing loss and hearing needs in an adult homeless population: a prospective cross-sectional study. CMAJ Open. 2020 Jan-Mar;8(1):E199-E204 Authors: Noel CW, Mok F, Wu V, Eskander A, Yao CMKL, Hwang SW, Lichter M, Reekie M, Smith S, Syrett I, Zirkle M, Lin V, Lee JM Abstract BACKGROUND: Given that hearing loss is associated with increased social isolation, reduced earning potential and neurocognitive disease, findings of uncorrected...
Thu Mar 19, 2020 12:23
Related ArticlesEarly Detection of Cancer: Evaluation of MR Imaging Grading Systems in Patients with Suspected Nasopharyngeal Carcinoma. AJNR Am J Neuroradiol. 2020 Mar;41(3):515-521 Authors: King AD, Woo JKS, Ai QY, Mo FKF, So TY, Lam WKJ, Tse IOL, Vlantis AC, Yip KWN, Hui EP, Ma BBY, Chiu RWK, Chan ATC, Lo YMD, Chan KCA Abstract BACKGROUND AND PURPOSE: We evaluated modifications to our contrast-enhanced MR imaging grading system for symptomatic...
Thu Mar 19, 2020 12:23
Related ArticlesCETUXIMAB AND RADIOTHERAPY VERSUS CISPLATIN AND RADIOTHERAPY FOR LOCALLY ADVANCED HEAD AND NECK CANCER: LONG TERM SURVIVAL AND TOXICITY OUTCOMES OF A RANDOMIZED PHASE II TRIAL. Int J Radiat Oncol Biol Phys. 2020 Mar 14;: Authors: Maddalo M, Borghetti P, Tomasini D, Corvò R, Bonomo P, Petrucci A, Paiar F, Lastrucci L, Bonù ML, Greco D, Costa L, Pegurri L, Triggiani L, Belgioia L, Desideri I, Grisanti S, Buglione M, Magrini SM Abstract ...
Thu Mar 19, 2020 12:23
Related ArticlesCepstral Measures to Analyze Vocal Fatigue in Individuals With Hyperfunctional Voice Disorder. J Voice. 2020 Mar 14;: Authors: Mahalingam S, Boominathan P, Arunachalam R, Venkatesh L, Srinivas S Abstract OBJECTIVE: Cepstral measures are sensitive to slightest deviance in voice quality. Vocal fatigue is an initial symptom of a voice disorder. This study aimed (1) to assess the correlation of vocal fatigue and cepstral measures and...
Thu Mar 19, 2020 12:23
Related ArticlesAn assessment of histological margins and recurrence of completely excised cutaneous SCC. J Plast Reconstr Aesthet Surg. 2019 Oct 05;: Authors: Sepehripour S, Dawood O, Hatter S, Williams L, Zahd Z, Liebmann R, Dheansa B Abstract There is a paucity of data relating to histological margins of cutaneous squamous cell carcinoma (cSCC) and local recurrence. Retrospective data were collected for 721 patients with cSCC treated at Queen...
Thu Mar 19, 2020 12:23
Related ArticlesRelationship of patient age to tumor factors and outcomes among patients undergoing sentinel node biopsy for melanoma. Am J Surg. 2020 Mar 10;: Authors: Radu S, Han D, Fowler G, Han G, Fortino J, Vetto JT Abstract INTRODUCTION: Patient age has been intermittently associated with demographics and outcomes in cutaneous melanoma. We looked at the association of age and patient demographics, tumor features, and melanoma-related outcomes...
Thu Mar 19, 2020 12:23
Related ArticlesGender and compensation among surgical specialties in the Veterans Health Administration. Am J Surg. 2020 Feb 27;: Authors: Maxwell JH, Randall JA, Dermody SM, Hussaini AS, Rao H, Nathan AS, Malekzadeh S, Litvack JR Abstract BACKGROUND: A gender pay gap has been reported across many professions, including medicine. METHODS: Surgeons employed at complex Veterans Affairs Medical Centers (VAMC) nationwide in 2016 were identified....
Thu Mar 19, 2020 12:23
Related ArticlesAnxiety and depression in patients with nasal septal deviation. Am J Otolaryngol. 2020 Feb 27;:102450 Authors: Ma Q, Su K, Fu Z, Wang P, Shi H Abstract OBJECTIVE: Nasal septal deviation (NSD) has a significant impact on patients' quality of life; however, there have been limited studies examining the psychological status of NSD patients. In this study, symptoms of depression and anxiety were investigated between NSD patients and controls...
Thu Mar 19, 2020 12:23
Related ArticlesADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis. Cancer Cell. 2020 Mar 16;37(3):324-339.e8 Authors: Liu H, Kuang X, Zhang Y, Ye Y, Li J, Liang L, Xie Z, Weng L, Guo J, Li H, Ma F, Chen X, Zhao S, Su J, Yang N, Fang F, Xie Y, Tao J, Zhang J, Chen M, Peng C, Sun L, Zhang X, Liu J, Han L, Xu X, Hung MC, Chen X Abstract Here, we show that tumor ADORA1 deletion suppresses cell growth in human melanoma...
Thu Mar 19, 2020 12:23
Related ArticlesCorrection to: Core Rehabilitation Outcome Set for Single Sided Deafness (CROSSSD) study: protocol for an international consensus on outcome measures for single sided deafness interventions using a modified Delphi survey. Trials. 2020 Mar 17;21(1):272 Authors: Katiri R, Hall DA, Buggy N, Hogan N, Horobin A, van de Heyning P, Firszt JB, Bruce IA, Kitterick PT Abstract Following the publication of our article [1], the authors have notified...
Thu Mar 19, 2020 12:23
Related ArticlesRationale and design of a randomised controlled trial investigating the effect of multidisciplinary nutritional rehabilitation for patients treated for head and neck cancer (the NUTRI-HAB trial). Nutr J. 2020 Mar 17;19(1):21 Authors: Kristensen MB, Wessel I, Beck AM, Dieperink KB, Mikkelsen TB, Møller JK, Zwisler AD Abstract BACKGROUND: Eating problems frequently affect quality of life and physical, psychological and social function...
Thu Mar 19, 2020 12:23
Related ArticlesA convolutional neural network-based system to classify patients using FDG PET/CT examinations. BMC Cancer. 2020 Mar 17;20(1):227 Authors: Kawauchi K, Furuya S, Hirata K, Katoh C, Manabe O, Kobayashi K, Watanabe S, Shiga T Abstract BACKGROUND: As the number of PET/CT scanners increases and FDG PET/CT becomes a common imaging modality for oncology, the demands for automated detection systems on artificial intelligence (AI) to prevent...
Thu Mar 19, 2020 12:23
Related ArticlesImmunological effects of nivolumab immunotherapy in patients with oral cavity squamous cell carcinoma. BMC Cancer. 2020 Mar 17;20(1):229 Authors: Xiong Y, Neskey DM, Horton JD, Paulos CM, Knochelmann HM, Armeson KE, Young MRI Abstract BACKGROUND: Although checkpoint blockades have become widely used, the immunological impact in cancer patients, especially those with oral cavity squamous cell carcinoma (OCSCC), has not been well studied....
Thu Mar 19, 2020 12:23
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