Related ArticlesFive year follow-up of undiagnosed sleep apnea in patients undergoing coronary artery bypass graft surgery. J Cardiovasc Surg (Torino). 2020 Mar 17;: Authors: Hogan AM, Ibrahim S, Moylan MJ, McCormack DJ, Openshaw AM, Cormack F, Shipolini A Abstract BACKGROUND: We aimed to study prospectively the nature and effect of sleep apnea-hypopnea syndrome (SAHS) in patients undergoing coronary artery bypass graft (CABG) surgery over five years...
Thu Mar 19, 2020 14:09
Related ArticlesBurn pit exposure in military personnel: is there an effect on sleep-disordered breathing? Sleep Breath. 2020 Mar 17;: Authors: Powell TA, Mysliwiec V, Aden JK, Morris MJ Abstract PURPOSE: Exposure to elevated concentrations of respirable particulate matter (< 10 μm) may influence sleep-disordered breathing. Burn pits as utilized by the US military in the Middle East until 2011 produced elevated particle matter concentrations. We seek...
Thu Mar 19, 2020 12:48
Related ArticlesResolution of Long-Standing Diabetes Mellitus Two Years After Surgery for Growth Hormone Producing Pituitary Tumor. Int Med Case Rep J. 2020;13:71-75 Authors: Sreeramaneni PGA, Ghanta RK Abstract Excess serum growth hormone (GH) induces insulin resistance leading to reduced uptake of glucose in peripheral tissues, gluconeogenesis in the liver and lipolysis and finally an increase in the blood glucose levels. We report a case where a 54-year-old...
Thu Mar 19, 2020 12:48
Related ArticlesOvernight Pulse Oximetry to Determine Prognostic Factors in Subjects With Amyotrophic Lateral Sclerosis. Respir Care. 2020 Mar 17;: Authors: Bote SM, Martinez NP, Amarilla CE, Ugalde PF, Gonzalez-Bermejo J, Collado NF, Gamez BJ Abstract BACKGROUND: The objective of the current study was to determine whether overnight pulse oximetry in patients with amyotrophic lateral sclerosis is prognostic of the onset of awake respiratory failure and...
Thu Mar 19, 2020 12:48
Related Articles[Primary Prevention of Acute Stroke]. Praxis (Bern 1994). 2020;109(4):277-289 Authors: Scutelnic A, Streit S, Sarikaya H, Jung S, Heldner MR Abstract Primary Prevention of Acute Stroke Abstract. Strokes are frequent. Vascular risk factors are increasing the stroke risk. Most vascular risk factors are treatable. Their therapy is important in the primary prevention of stroke. According to the INTERSTROKE study, arterial hypertension, inactivity,...
Thu Mar 19, 2020 12:48
Related Articles[CME-Answers: 'Obstructive Sleep Apnea: A Common Disease']. Praxis (Bern 1994). 2020;109(4):309-310 Authors: Kohler M PMID: 32183645 [PubMed - in process]
Thu Mar 19, 2020 12:48
Related ArticlesPain Squad+ smartphone app to support real-time pain treatment for adolescents with cancer: protocol for a randomised controlled trial. BMJ Open. 2020 Mar 16;10(3):e037251 Authors: Jibb L, Nathan PC, Breakey V, Fernandez C, Johnston D, Lewis V, McKillop S, Patel S, Sabapathy C, Strahlendorf C, Victor JC, Moretti ME, Nguyen C, Hundert A, Cassiani C, El-Khechen Richandi G, Insull H, Hamilton R, Fang G, Kuczynski S, Stinson J Abstract INTRODUCTION:...
Thu Mar 19, 2020 12:44
Related ArticlesObservational retrospective study of UK national success, risks and costs for 319,105 IVF/ICSI and 30,669 IUI treatment cycles. BMJ Open. 2020 Mar 16;10(3):e034566 Authors: Bahadur G, Homburg R, Bosmans JE, Huirne JAF, Hinstridge P, Jayaprakasan K, Racich P, Alam R, Karapanos I, Illahibuccus A, Al-Habib A, Jauniaux E Abstract OBJECTIVE: To compare success rates, associated risks and cost-effectiveness between intrauterine insemination...
Thu Mar 19, 2020 12:44
Related ArticlesPhase II double-blind randomised controlled trial of exogenous administration of melatonin in chronic pain (DREAM-CP): a study protocol. BMJ Open. 2020 Mar 16;10(3):e034443 Authors: Adam R, Kanakarajan S, Onyeakazi U, Columb M, Galley H Abstract INTRODUCTION: Chronic pain is prevalent, and approximately half of patients with chronic pain experience sleep disturbance. Exogenous melatonin is licensed to treat primary insomnia and there...
Thu Mar 19, 2020 12:44
Related ArticlesLong-term patient satisfaction and durability of laparoscopic anti-reflux surgery in a large Danish cohort: study protocol for a retrospective cohort study with development of a novel scoring system for patient selection. BMJ Open. 2020 Mar 16;10(3):e034257 Authors: Sanberg Ljungdalh J, Rubin KH, Durup J, Houlind KC Abstract INTRODUCTION: Laparoscopic anti-reflux surgery is standard of care in surgical treatment of gastro-oesophageal...
Thu Mar 19, 2020 12:44
Related ArticlesAccess and use of oxytocin for postpartum haemorrhage prevention: a pre-post study targeting the poorest in six Mesoamerican countries. BMJ Open. 2020 Mar 16;10(3):e034084 Authors: Kamath AM, Schaefer AM, Palmisano EB, Johanns CK, Gonzalez Marmol A, Dinarte Mendoza M, Schwarzbauer K, Zúñiga-Brenes P, Ríos-Zertuche D, Iriarte E, Mokdad AH, Hernandez Prado B Abstract OBJECTIVES: Haemorrhage remains the leading cause of maternal mortality...
Thu Mar 19, 2020 12:44
Related ArticlesPrevalence of Neisseria gonorrhoeae and Chlamydia trachomatis in men having sex with men in Port-au-Prince, Haiti: a cross-sectional study. BMJ Open. 2020 Mar 16;10(3):e033976 Authors: Jean Louis F, Galbaud G, Leonard M, Pericles E, Journel I, Buteau J, Boncy J, Jean Francois R, Domercant JW Abstract OBJECTIVES: Over the last 15 years, the prevalence of HIV in Haiti has stabilised to around 2.0%. However, key populations remain at higher...
Thu Mar 19, 2020 12:44
Related ArticlesWillingness, perceived barriers and motivators in adopting mobile applications for health-related interventions among older adults: a scoping review protocol. BMJ Open. 2020 Mar 16;10(3):e033870 Authors: Ahmad NA, Mat Ludin AF, Shahar S, Mohd Noah SA, Mohd Tohit N Abstract INTRODUCTION: The world's older population continues to grow at an unprecedented rate. An ageing population poses a great challenge to our healthcare system that requires...
Thu Mar 19, 2020 12:44
Related ArticlesChanges to cardiovascular risk factors over 7 years: a prospective cohort study of in situ urbanised residents in the Chaoyang District of Beijing. BMJ Open. 2020 Mar 16;10(3):e033548 Authors: Li Z, Yu S, Han X, Liu J, Yao H Abstract OBJECTIVES: To examine changes in cardiovascular risk factors of in situ urbanised residents between 2010 and 2017. DESIGN: Population-based cohort study. SETTING: The Chaoyang District...
Thu Mar 19, 2020 12:44
Related ArticlesAssociation between uterine contractions before elective caesarean section and transient tachypnoea of the newborn: a retrospective cohort study. BMJ Open. 2020 Mar 16;10(3):e033154 Authors: Shinohara S, Amemiya A, Takizawa M Abstract OBJECTIVE: We evaluated the association between the presence of predelivery uterine contractions and transient tachypnoea of the newborn (TTN) in women undergoing an elective caesarean section. ...
Thu Mar 19, 2020 12:44
Related ArticlesPsychometric validation of a Patient-Centred Quality of Cancer Care Questionnaire in Mexico. BMJ Open. 2020 Mar 16;10(3):e033114 Authors: Doubova SV, Martinez-Vega IP, Gutiérrez-De-la-Barrera M, Infante-Castañeda C, Aranda-Flores CE, Monroy A, Gómez-Laguna L, Knaul FM, Pérez-Cuevas R Abstract OBJECTIVES: To develop and validate a Patient-Centred Quality of Cancer Care Questionnaire in Spanish (PCQCCQ-S) appropriate to the Mexican context....
Thu Mar 19, 2020 12:44
Related ArticlesPhase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol. BMJ Open. 2020 Mar 16;10(3):e033009 Authors: Kong A, Good J, Kirkham A, Savage J, Mant R, Llewellyn L, Parish J, Spruce R, Forster M, Schipani S, Harrington K, Sacco J, Murray P, Middleton G, Yap C, Mehanna H Abstract INTRODUCTION:...
Thu Mar 19, 2020 12:44
Related ArticlesDouble burden of malnutrition in children aged 24 to 59 months by socioeconomic status in five South Asian countries: evidence from demographic and health surveys. BMJ Open. 2020 Mar 16;10(3):e032866 Authors: Hossain FB, Shawon MSR, Al-Abid MSU, Mahmood S, Adhikary G, Bulbul MMI Abstract OBJECTIVES: We aimed to investigate the socioeconomic inequalities in the burden of underweight and overweight among children in South Asia. We also...
Thu Mar 19, 2020 12:44
Related ArticlesOutcome reporting bias in Cochrane systematic reviews: a cross-sectional analysis. BMJ Open. 2020 Mar 16;10(3):e032497 Authors: Shah K, Egan G, Huan LN, Kirkham J, Reid E, Tejani AM Abstract BACKGROUND: Discrepancies in outcome reporting (DOR) between protocol and published studies include inclusions of new outcomes, omission of prespecified outcomes, upgrade and downgrade of secondary and primary outcomes, and changes in definitions...
Thu Mar 19, 2020 12:44
Related ArticlesIndoor environmental quality and learning outcomes: protocol on large-scale sensor deployment in schools. BMJ Open. 2020 Mar 16;10(3):e031233 Authors: Palacios Temprano J, Eichholtz P, Willeboordse M, Kok N Abstract INTRODUCTION: Exposure to poor environmental conditions has been associated with deterioration of physical and mental health, and with reduction of cognitive performance. Environmental conditions may also influence cognitive...
Thu Mar 19, 2020 12:44
Related ArticlesQualitative exploration of the intersection between social influences and cultural norms in relation to the development of alcohol use behaviour during adolescence. BMJ Open. 2020 Mar 16;10(3):e030556 Authors: MacArthur GJ, Hickman M, Campbell R Abstract OBJECTIVES: Few contemporary studies have examined peer and social drivers of alcohol use during mid-adolescence. We sought to explore young people's perspectives on socio-cultural influences...
Thu Mar 19, 2020 12:44
The authors’ of this paper would like to recognise Anoop Anugraha as the first author. In the original version of this manuscript the list of authors was presented incorrectly, and this has now been rectified. The authors apologise for this error.
Thu Mar 19, 2020 02:00
Related ArticlesCombining Mobile Crowdsensing and Ecological Momentary Assessments in the Healthcare Domain. Front Neurosci. 2020;14:164 Authors: Kraft R, Schlee W, Stach M, Reichert M, Langguth B, Baumeister H, Probst T, Hannemann R, Pryss R Abstract The increasing prevalence of smart mobile devices (e.g., smartphones) enables the combined use of mobile crowdsensing (MCS) and ecological momentary assessments (EMA) in the healthcare domain. By correlating...
Thu Mar 19, 2020 12:32
Related ArticlesCorrigendum: Kv1.3 Channel as a Key Therapeutic Target for Neuroinflammatory Diseases: State of the Art and Beyond. Front Neurosci. 2020;14:163 Authors: Wang X, Li G, Guo J, Zhang Z, Zhang S, Zhu Y, Cheng J, Yu L, Ji Y, Tao J Abstract [This corrects the article DOI: 10.3389/fnins.2019.01393.].PMID: 32184707 [PubMed - in process]
Thu Mar 19, 2020 12:32
Related ArticlesRestoring Somatosensation: Advantages and Current Limitations of Targeting the Brainstem Dorsal Column Nuclei Complex. Front Neurosci. 2020;14:156 Authors: Loutit AJ, Potas JR Abstract Current neural prostheses can restore limb movement to tetraplegic patients by translating brain signals coding movements to control a variety of actuators. Fast and accurate somatosensory feedback is essential for normal movement, particularly dexterous...
Thu Mar 19, 2020 12:32
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Thu Mar 19, 2020 12:32
Related ArticlesDexmedetomidine Alleviated Endoplasmic Reticulum Stress via Inducing ER-phagy in the Spinal Cord of Neuropathic Pain Model. Front Neurosci. 2020;14:90 Authors: Liu Y, Wang S, Wang Z, Ding M, Li X, Guo J, Han G, Zhao P Abstract Studies demonstrated that spinal autophagy was impaired in spinal nerve ligation (SNL) rats. However, the relationship of endoplasmic reticulum (ER) stress and ER-phagy and whether dexmedetomidine (DEX) modulates...
Thu Mar 19, 2020 12:32
Related ArticlesDihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway. Mol Carcinog. 2020 Mar 18;: Authors: Pan H, Liu F, Wang J, Zhao M, Wang D, Jia C, Wang T, Chen Z, Fan Y, Liang D, Meng Q Abstract Dihydromethysticin (DHM), a natural compound derived from Kava, has been reported to be effective against mental disorders and some malignant tumors. However, little is known about the...
Thu Mar 19, 2020 13:32
Related ArticlesEffect of KIF22 on promoting proliferation and migration of gastric cancer cells via MAPK-ERK pathways. Chin Med J (Engl). 2020 Mar 16;: Authors: Yu ZY, Jiang XY, Zhao RR, Qin JJ, Luo CJ, Ren YX, Ren W, Ma ZJ, Jiao ZY Abstract BACKGROUND: Gastric cancer (GC) is one of the most globally prevalent cancers in the world. The pathogenesis of GC has not been fully elucidated, and there still lacks effective targeted therapeutics. The influence...
Thu Mar 19, 2020 13:32
Related ArticlesAntitumor activity of a novel Aurora A/B kinases inhibitor TY-011 against gastric cancer by inducing DNA damage. Anticancer Drugs. 2020 Mar 16;: Authors: Jiang T, Liu W, Lu Y, Fang Y, Chen R, Zhang W, Liu X, Zhang X Abstract TY-011, a novel Aurora A/B kinases inhibitor, was found in our previous study to exhibit prominent inhibitory effects on growth of gastric cancer, both in vitro and in vivo. To clarify the mechanisms of TY-011...
Thu Mar 19, 2020 13:32
Related ArticlesGrowth inhibitory role of the p53 activator SCH 529074 in non‑small cell lung cancer cells expressing mutant p53. Oncol Rep. 2020 Mar 17;: Authors: Nenkov M, Ma Y, Haase D, Zhou Z, Li Y, Petersen I, Lu G, Chen Y Abstract Mutations of p53 occur in approximately 50% of advanced non‑small cell lung cancer (NSCLC) cases, leading to loss of tumor suppressive function and/or gain of p53 oncogenic activity. Reactivation of mutant p53 and...
Thu Mar 19, 2020 13:32
Related ArticlesDeletion of p21 expression accelerates cartilage tissue repair via chondrocyte proliferation. Mol Med Rep. 2020 Mar 13;: Authors: Ibaraki K, Hayashi S, Kanzaki N, Hashimoto S, Kihara S, Haneda M, Takeuchi K, Niikura T, Kuroda R Abstract Articular cartilage tissue has a poor healing potential, and when subjected to traumatic damage this tissue undergoes cartilage degeneration and osteoarthritis. The association between the regulation...
Thu Mar 19, 2020 13:32
Related ArticlesUrsolic acid promotes apoptosis, autophagy, and chemosensitivity in gemcitabine-resistant human pancreatic cancer cells. Phytother Res. 2020 Mar 17;: Authors: Lin JH, Chen SY, Lu CC, Lin JA, Yen GC Abstract Gemcitabine (GEM) resistance in pancreatic adenocarcinoma mediated by the receptor for advanced glycation end products (RAGE) has been demonstrated. Therefore, investigating the safety and the potential of new auxiliary methods...
Thu Mar 19, 2020 12:32
Related ArticlesCellular Senescence as a Therapeutic Target for Age-Related Diseases: A Review. Adv Ther. 2020 Mar 17;: Authors: Amaya-Montoya M, Pérez-Londoño A, Guatibonza-García V, Vargas-Villanueva A, Mendivil CO Abstract Life expectancy has increased substantially over the last few decades, leading to a worldwide increase in the prevalence and burden of aging-associated diseases. Recent evidence has proven that cellular senescence contributes...
Thu Mar 19, 2020 12:32
Related ArticlesRegulation of Cancer Immune Checkpoint: Mono- and Poly-Ubiquitination: Tags for Fate. Adv Exp Med Biol. 2020;1248:295-324 Authors: Yao H, Xu J Abstract The antagonism, stalemate and compromise between the immune system and tumor cells is closely associated with tumor development and progression. In recent years, tumor immunotherapy has made continuous breakthroughs. It has become an important approach for cancer treatment, improving...
Thu Mar 19, 2020 12:32
Related ArticlesRegulation of Nrf2 and NF-κB during lead toxicity in bovine granulosa cells. Cell Tissue Res. 2020 Feb 18;: Authors: Aglan HS, Gebremedhn S, Salilew-Wondim D, Neuhof C, Tholen E, Holker M, Schellander K, Tesfaye D Abstract Lead (Pb), one of the pervasive and protracted environmental heavy metals, is believed to affect the female reproductive system in many species. The Nrf2 and NF-κB are the two key transcriptional factors regulating...
Thu Mar 19, 2020 12:32
Related ArticlesCitron Rho-Interacting Serine/Threonine Kinase Promotes HIF1a-CypA Signaling and Growth of Human Pancreatic Adenocarcinoma. Biomed Res Int. 2020;2020:9210891 Authors: Cong L, Bai Z, Du Y, Cheng Y Abstract In human pancreatic ductal adenocarcinoma (PDAC), the cyclophilin A (CypA) is overexpressed and promotes the development of PDAC. However, the mechanism underlying cyclophilin A expression remains elusive. Here, we reported that...
Thu Mar 19, 2020 12:32
Related ArticlesDesign, Synthesis and Biological Evaluation of Ciprofloxacin- Peptide Conjugates as Anticancer Agents. Iran J Pharm Res. 2019;18(4):1823-1830 Authors: Esfandiari Mazandaran K, Mirshokraee SA, Didehban K, Houshdar Tehrani MH Abstract Cancer has emerged as a leading cause of death throughout the world. Peptides are a novel class of anticancer agents that can specifically target cancer cells with low toxicity to normal tissues and thus,...
Thu Mar 19, 2020 12:32
Related ArticlesSynthesis and in-vitro Evaluation of S-allyl Cysteine Ester - Caffeic Acid Amide Hybrids as Potential Anticancer Agents. Iran J Pharm Res. 2019;18(4):1770-1789 Authors: Castrillón W, Herrera-R A, Prieto LJ, Conesa-Milián L, Carda M, Naranjo T, Maldonado ME, Cardona-G W Abstract We have synthesized a series of S-allyl cysteine ester-caffeic acid amide hybrids and evaluated them in order to determine their possible anticancer activity...
Thu Mar 19, 2020 12:32
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