Related ArticlesA convolutional neural network-based system to classify patients using FDG PET/CT examinations. BMC Cancer. 2020 Mar 17;20(1):227 Authors: Kawauchi K, Furuya S, Hirata K, Katoh C, Manabe O, Kobayashi K, Watanabe S, Shiga T Abstract BACKGROUND: As the number of PET/CT scanners increases and FDG PET/CT becomes a common imaging modality for oncology, the demands for automated detection systems on artificial intelligence (AI) to prevent...
Related ArticlesImmunological effects of nivolumab immunotherapy in patients with oral cavity squamous cell carcinoma. BMC Cancer. 2020 Mar 17;20(1):229 Authors: Xiong Y, Neskey DM, Horton JD, Paulos CM, Knochelmann HM, Armeson KE, Young MRI Abstract BACKGROUND: Although checkpoint blockades have become widely used, the immunological impact in cancer patients, especially those with oral cavity squamous cell carcinoma (OCSCC), has not been well studied....
Related ArticlesHistologic, Histomorphometric, and Clinical Analysis of the Effects of Growth Factors in a Fibrin Network Used in Maxillary Sinus Augmentation. Int J Environ Res Public Health. 2020 Mar 15;17(6): Authors: Cinar IC, Gultekin BA, Saglanmak A, Yalcin S, Olgac V, Mijiritsky E Abstract This randomized controlled clinical trial evaluated the effect of mineralized plasmatic matrix (MPM), comprised of synthetic graft and platelet concentrates,...
Related ArticlesThe Significance of the Dysregulation of Canonical Wnt Signaling in Head and Neck Squamous Cell Carcinomas. Cells. 2020 Mar 15;9(3): Authors: Paluszczak J Abstract The knowledge about the molecular alterations which are found in head and neck squamous cell carcinomas (HNSCC) has much increased in recent years. However, we are still awaiting the translation of this knowledge to new diagnostic and therapeutic options. Among the many...
Related ArticlesHigh-grade B-cell Lymphoma with MYC and BCL2 Rearrangement Arising from Follicular Lymphoma: Presentation as a Large Peripancreatic Mass. Diagnostics (Basel). 2020 Mar 14;10(3): Authors: Shestakova A, Rezk S, Ghasemizadeh D, Nael A, Zhao X Abstract Follicular lymphoma, the second most common non-Hodgkin lymphoma (NHL), primarily affects adults and shows an indolent clinical course. Rare cases of follicular lymphoma transform to a...
Related ArticlesGlobal RNA Expression and DNA Methylation Patterns in Primary Anaplastic Thyroid Cancer. Cancers (Basel). 2020 Mar 13;12(3): Authors: Ravi N, Yang M, Mylona N, Wennerberg J, Paulsson K Abstract Anaplastic thyroid cancer (ATC) is one of the most malignant tumors, with a median survival of only a few months. The tumorigenic processes of this disease have not yet been completely unraveled. Here, we report an mRNA expression and DNA methylation...
Related ArticlesGanglioside GM3 Up-Regulate Chondrogenic Differentiation by Transform Growth Factor Receptors. Int J Mol Sci. 2020 Mar 13;21(6): Authors: Ryu JS, Seo SY, Jeong EJ, Kim JY, Koh YG, Kim YI, Choo YK Abstract Mesenchymal stem cells, also known as multipotent stromal progenitor cells, can differentiate into cells of mesodermal lineage. Gangliosides are sialic acid-conjugated glycosphingolipids that are believed to regulate cell differentiation...
Related ArticlesEpigenetic Modification of CFTR in Head and Neck Cancer. J Clin Med. 2020 Mar 09;9(3): Authors: Shin Y, Kim M, Won J, Kim J, Oh SB, Lee JH, Park K Abstract Cystic fibrosis transmembrane conductance regulator (CFTR), a cyclic AMP (cAMP)-regulated chloride channel, is critical for secretion and absorption across diverse epithelia. Mutations or absence of CFTR result in pathogeneses, including cancer. While CFTR has been proposed as...
Related ArticlesmiR-152 inhibits the proliferation and invasion of chordoma cells by targeting HOXC8. J Int Med Res. 2019 Oct;47(10):5185-5193 Authors: Fang X, Yan R PMID: 31638463 [PubMed - indexed for MEDLINE]
Related ArticlesDysphonia Due to Vocal Cord Injury After Rigid Bronchoscopy: A Case Study With 1-Year Bronchoscopic Follow-up. J Bronchology Interv Pulmonol. 2019 10;26(4):e52-e55 Authors: Youssef SJ, Orbelo DM, Sakata KK, Zimmermann TM, Pittelko RL, Nelson DR, Midthun DE, Edell ES, Ekbom DC PMID: 31569103 [PubMed - indexed for MEDLINE]
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Related ArticlesCutaneous Pleomorphic Fibromas Arising in Patients with Germline TP53 Mutations. J Cutan Pathol. 2020 Mar 18;: Authors: Cloutier JM, Shalin SC, Lindberg M, Gardner JM, Fernandez-Pol S, Zaba L, Novoa R, Brown RA Abstract Pleomorphic fibromas are rare benign cutaneous neoplasms associated with deletion/loss of chromosomes 13q and 17p, where RB1 and TP53 are located, respectively. Herein, we report five cases of pleomorphic fibroma arising...
Related ArticlesPure Primary Ovarian Carcinoid Tumor. Int J Gynecol Pathol. 2020 Mar 16;: Authors: Halvorson TS, Robinson RA, Samuelson MI Abstract Primary ovarian carcinoid tumors are uncommon neoplasms that typically arise in the context of a mature cystic teratoma. Pure primary ovarian carcinoid tumors (PPOCTs) are rare and present as a solid ovarian mass in which, by definition, elements of an associated teratoma or other neoplasm are absent. We...
Targeting Epigenetic Dependencies in Solid Tumors: Evolutionary Landscape Beyond Germ Layers Origin.
Related ArticlesTargeting Epigenetic Dependencies in Solid Tumors: Evolutionary Landscape Beyond Germ Layers Origin. Cancers (Basel). 2020 Mar 13;12(3): Authors: Citron F, Fabris L Abstract Extensive efforts recently witnessed the complexity of cancer biology; however, molecular medicine still lacks the ability to elucidate hidden mechanisms for the maintenance of specific subclasses of rare tumors characterized by the silent onset and a poor prognosis...
Related ArticlesIdentification of PLK1 as a New Therapeutic Target in Mucinous Ovarian Carcinoma. Cancers (Basel). 2020 Mar 13;12(3): Authors: Affatato R, Carrassa L, Chilà R, Lupi M, Restelli V, Damia G Abstract Mucinous epithelial ovarian cancer (mEOC) is a rare subset of epithelial ovarian cancer. When diagnosed at a late stage, its prognosis is very poor, as it is quite chemo-resistant. To find new therapeutic options for mEOC, we performed high-throughput...
Related ArticlesAdrenal myelolipoma: from tumorigenesis to management. Pan Afr Med J. 2019;34:180 Authors: Mhammedi WA, Ouslim H, Ouraghi A, Irzi M, Elhoumaidi A, Elhoumaidi A, Chennoufi M, Mokhtari M, Elmouden A, Barki A Abstract Adrenal myelolipoma (MLS) is a rare, benign and non-functional neoplasm, composed of adipose tissue and myeloid. We report a rare case of adrenal myelolipoma of a 20-year-old female revealed with chronic abdominal pain. Computed...
Related Articles[Voluminous epidermoid cyst compressing the upper cervical spinal cord: about a clinical case]. Pan Afr Med J. 2019;34:169 Authors: Lengane NI, Ouattara S, Zaghre N, Some MJM, Ouedraogo T, Ouedraogo BP Abstract Epidermoid cyst is a benign embryonic tumor. It is an anomalous localization of ectoderm-derived tissue. Cervical epidermoid cyst is rare. It can cause diagnostic difficulties, especially in patients with voluminous and compressive...
Related Articles[Testicular tumors in prepubertal boys-organ preservation possible more often than expected]. Urologe A. 2020 Mar;59(3):278-283 Authors: Stein R, Dürken M, Zahn K, Younsi N Abstract In prepubertal boys, testicular tumors are rare with an incidence between 2 and 5/million. In contrast to testicular tumors in adolescents and adults, more than 2/3 of these tumors are benign. Unfortunately, in Germany in most cases, only malignant tumors...
Related ArticlesAn Intra-abdominal Solid-cystic Desmoid That Emerged after Distal Gastrectomy. Intern Med. 2019;58(24):3525-3529 Authors: Takinami M, Matsubayashi H, Ishiwatari H, Uesaka K, Okamura Y, Sasaki K, Ohike N, Hirabayashi K, Ono H Abstract Desmoid is a locally aggressive fibroblastic neoplasm, typically showing a heterogeneous solid mass, and its pathogenesis is multifactorial, including surgical scars. We herein report a rare case of an...
Related ArticlesCurrent trends and 30-day surgical outcomes for thyroglossal duct cyst excision in children. Int J Pediatr Otorhinolaryngol. 2020 Jan;128:109725 Authors: Cheng J, Lerebours R, Lee HJ Abstract OBJECTIVE: Identify current trends, adverse events, and clinical predictors in children treated with thyroglossal duct cyst surgery. METHODS: Cross-sectional analysis using American College of Surgeons (ACS) National Surgical Quality Improvement...
Related ArticlesRadiologic, genetic, and endocrine findings in isolated congenital nasal pyriform aperture stenosis patients. Int J Pediatr Otorhinolaryngol. 2020 Jan;128:109705 Authors: Ruda J, Grischkan J, Allarakhia Z Abstract BACKGROUND: Congenital nasal pyriform aperture stenosis (CNPAS) is a rare cause of upper airway obstruction in neonates. It can occur either associated with a solitary median maxillary central incisor (SMMCI) in 40-75% of cases...
Related ArticlesMerkel cell polyomavirus is implicated in a subset of Merkel cell carcinomas, in the Indian subcontinent. Microb Pathog. 2019 Dec;137:103778 Authors: Arora R, Rekhi B, Chandrani P, Krishna S, Dutt A Abstract Merkel cell carcinoma is a rare, lethal cancer histopathologically composed of cells showing similarity with mechanoreceptor Merkel cells. Merkel cell tumors manifest in two distinct forms. While a virus called Merkel cell polyomavirus...
Related ArticlesHyperandrogenism and Adrenocortical Tumors. Front Horm Res. 2019;53:92-99 Authors: Di Dalmazi G Abstract Androgen-secreting tumors are a rare cause of hyperandrogenism of adrenal origin. Although these tumors are identified in less than 2% of patients, the prevalence of adrenocortical carcinomas is relevant (2/3 of the cases). Those tumors are associated with simultaneous elevation of several androgens, mainly androstenedione, DHEAS,...
Related ArticlesAndrogen-Secreting Ovarian Tumors. Front Horm Res. 2019;53:100-107 Authors: Macut D, Ilić D, Mitrović Jovanović A, Bjekić-Macut J Abstract About 1% of ovarian tumors that comprise testicular cell types can cause hyperandrogenism followed by characteristic virilization. Androgenic group of tumors originated mainly from sex-cord stromal ovarian tumors are including steroid cell tumors, Leydig tumors, granulosa cell tumors, Sertoli cell...
Related ArticlesPrimary maxillofacial chordoma: a rare case report and literature review. J Int Med Res. 2019 Sep;47(9):4575-4579 Authors: Cui Y, Cui XY, Yu T, Zhu ZP, Wang X PMID: 31441347 [PubMed - indexed for MEDLINE]
Related ArticlesAutoimmune hepatitis during preoperative chemotherapy in a patient with thymoma. Interact Cardiovasc Thorac Surg. 2019 10 01;29(4):635-637 Authors: Nishimura T, Tsunezuka H, Miyata N, Inoue M Abstract Autoimmune diseases associated with thymoma are well known, with myasthenia gravis being the most common, while autoimmune hepatitis (AIH) is extremely rare. The case of a 63-year-old woman with AIH that developed during preoperative chemotherapy...
Related ArticlesNew research strategies in retroperitoneal sarcoma. The case of TARPSWG, STRASS and RESAR: making progress through collaboration. Curr Opin Oncol. 2019 07;31(4):310-316 Authors: van Houdt WJ, Raut CP, Bonvalot S, Swallow CJ, Haas R, Gronchi A Abstract PURPOSE OF REVIEW: Retroperitoneal sarcoma (RPS) is a rare disease, and until recently, its natural history and outcome were poorly understood. Recently, collaborations between individual...
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Related ArticlesThe antilymphatic metastatic effect of hyaluronic acid in a mouse model of oral squamous cell carcinoma. Cancer Biol Ther. 2020 Mar 18;:1-8 Authors: Chen H, Wang M, Qi M, Tian Z, Wu W, Yang J, Zhang M, Tang L, Tang X Abstract Objectives: Lymphatic metastasis is the main cause of low patient survival in cases of oral squamous cell carcinoma (OSCC). Several animal models have been established to uncover the mechanism that regulates lymph...
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Related ArticlesDivergent response of low- versus high-threshold motor units to experimental muscle pain. J Physiol. 2020 Mar 18;: Authors: Martinez-Valdes E, Negro F, Farina D, Falla D Abstract KEY POINTS: The neural strategies behind the control of force during muscle pain are not well understood as previous research has been limited in assessing pain responses during low-force contractions only. Here we compared, for the first time, the behaviour...
Related ArticlesDoes the broad nature of sympathetic discharge affect our understanding regarding the impact of intermittent hypoxia on neurovascular transduction? J Physiol. 2020 Mar 18;: Authors: Klassen SA, Wiggins CC, Senefeld JW PMID: 32187381 [PubMed - as supplied by publisher]
Related ArticlesHyperthermia: The hotter the body, the hungrier the brain? J Physiol. 2020 Mar 18;: Authors: Fischer M, Tamariz-Ellemann A, Gliemann L PMID: 32187378 [PubMed - as supplied by publisher]
Related ArticlesGut microbiota sPARk vagus nerve excitation. J Physiol. 2020 Mar 18;: Authors: Singh A, Serre C, de Lartigue G PMID: 32187377 [PubMed - as supplied by publisher]
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Head and neck sarcomas: the first report addressing the duration of symptoms and diagnostic work up.
Related ArticlesHead and neck sarcomas: the first report addressing the duration of symptoms and diagnostic work up. Acta Otolaryngol. 2020 Mar 18;:1-5 Authors: Aalling M, Klug TE, Ovesen T Abstract Background: Head and neck sarcomas are rare and difficult to diagnose and manage.Aim: To describe a population of patients with head and neck sarcomas focusing on the effect of symptom duration and time to diagnosis on mortality and recurrence risk.Materials...
Related ArticlesCancer Mortality and Deprivation in the Proximity of Polluting Industrial Facilities in an Industrial Region of Spain. Int J Environ Res Public Health. 2020 Mar 13;17(6): Authors: Santos-Sánchez V, Córdoba-Doña JA, García-Pérez J, Escolar-Pujolar A, Pozzi L, Ramis R Abstract Residential proximity to industrial facilities that release pollutants is a source of exposure to a high number of toxics, many of them known or suspected carcinogens....
Related ArticlesSMARCE1-related Coffin-Siris Syndrome: Case report and otolaryngologic manifestations of the syndrome. Int J Pediatr Otorhinolaryngol. 2020 Jan;128:109735 Authors: Reed L, Grady A, Wilson C, Stocks R Abstract Coffin-Siris Syndrome (CSS) is a genetic syndrome associated with multiple congenital anomalies due to mutations in the BAF-complex or SOX gene. Although well characterized overall, the subunits of the BAF-complex or SOX gene affected...
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