Παρασκευή 20 Μαρτίου 2020


Ameliorating effects of sacral neuromodulation on gastric and small intestinal dysmotility mediated via a sacral afferent‐vagal efferent pathway
Sacral nerve stimulation improves gastric and small intestinal pace‐making activity and transit impaired by glucagon and rectal distention. The effect of sacral nerve stimulation was abolished by atropine and 4‐DAMP, suggesting a possible sacral afferent and vagal efferent neural pathway. Abstract Background/Aims In a recent study of sacral nerve stimulation (SNS) for colonic inflammation, a possible spinal‐vagal pathway was implicated. The aim of this study was to provide evidence for such...
The European Gastrointestinal Motility Society
Thu Mar 19, 2020 11:40
The Dishonesty of Informed Consent Rituals
The patient was moaning and swearing, his emergency visible from across the department: the flattened shoulder, the dent where the humeral head used to be, the yurt-shaped bulge below the clavicle where it was now. The paramedics had made a sling from a triangular muslin cravat, but he wasn’t using…
The New England Journal of Medicine: Search Results in Emergency Medicine
Thu Mar 19, 2020 02:00
Hereditary Angioedema
Hereditary angioedema is a rare, potentially life-threatening disorder characterized by attacks of cutaneous and submucosal swelling. Quincke first described its clinical presentation, and Osler’s recognition of the autosomal dominant inheritance pattern followed in 1888. The initial name of the…
The New England Journal of Medicine: Search Results in Emergency Medicine
Thu Mar 19, 2020 02:00
Opioid Prescribing in the Midst of Crisis — Myths and Realities
The once-simple act of writing an opioid prescription has become fraught. Physicians must check prescription monitoring databases to review patients’ histories, make sure their prescription complies with state limits on dose or number of days’ supply, and consider any practice-quality measures that…
The New England Journal of Medicine: Search Results in Emergency Medicine
Thu Mar 19, 2020 02:00
Am I Part of the Cure or Am I Part of the Disease? Keeping Coronavirus Out When a Doctor Comes Home
Last year, after a month of dry cough and shortness of breath while walking up the steep steps of Fillmore Street in San Francisco, Mary, my mother-in-law and housemate, noticed that she was becoming more and more easily winded. When her symptoms didn’t improve over the next several weeks, her…
The New England Journal of Medicine: Search Results in Emergency Medicine
Wed Mar 18, 2020 02:00
Clinicians’ and patients’ acceptance of the virtual clinic concept in maxillofacial surgery: a departmental survey
Publication date: Available online 19 March 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): T. Al-Izzi, J. Breeze, R. Elledge
British Journal of Oral and Maxillofacial Surgery
Thu Mar 19, 2020 11:36
Divergent response of low‐ versus high‐threshold motor units to experimental muscle pain
Key points The neural strategies behind the control of force during muscle pain are not well understood as previous research has been limited in assessing pain responses during low‐force contractions only. Here we compared, for the first time, the behaviour of motor units recruited at low and high forces in response to pain. The results showed that motor units activated at low forces were inhibited while those recruited at higher forces increased their activity in response to pain. When...
The Journal of Physiology
Thu Mar 19, 2020 11:18
Gut microbiota sPARk vagus nerve excitation
The Journal of Physiology
Thu Mar 19, 2020 11:18
Does the broad nature of sympathetic discharge affect our understanding regarding the impact of intermittent hypoxia on neurovascular transduction?
The Journal of Physiology
Thu Mar 19, 2020 11:18
Hyperthermia: The hotter the body, the hungrier the brain?
The Journal of Physiology
Thu Mar 19, 2020 11:18
Misdiagnosis, Mistreatment, and Harm — When Medical Care Ignores Social Forces
In a 2019 op-ed in the Wall Street Journal entitled "Take Two Aspirin and Call Me by My Pronouns," former University of Pennsylvania Dean of Medical Education Stanley Goldfarb echoed a dismissal that some physicians have been voicing for decades. Why should medical training focus on social factors,…
The New England Journal of Medicine: Search Results in Primary Care\Hospitalist\Clinical Practice
Thu Mar 19, 2020 02:00
Universal Disease Screening and Treatment — The Egyptian Example
Thirty years ago, chronic conditions such as diabetes, heart disease, and obesity accounted for less than 45% of the global disease burden. Today, they are the leading causes of death and disability worldwide, having surpassed infectious diseases such as HIV/AIDS and malaria. Although we are now…
The New England Journal of Medicine: Search Results in Primary Care\Hospitalist\Clinical Practice
Thu Mar 19, 2020 02:00
Screening and Treatment Program to Eliminate Hepatitis C in Egypt
Chronic hepatitis C virus (HCV) infection is a major global health problem affecting 1% of the world population. The Sustainable Development Goals that were adopted by the United Nations General Assembly in 2015 included combating viral hepatitis. In May 2016, the World Health Assembly set targets…
The New England Journal of Medicine: Search Results in Primary Care\Hospitalist\Clinical Practice
Thu Mar 19, 2020 02:00
Facing Covid-19 in Italy — Ethics, Logistics, and Therapeutics on the Epidemic’s Front Line
A few weeks ago, Dr. D. a middle-aged chief of cardiology at one of the biggest hospitals in northern Italy, developed a fever. Fearing he might have Covid-19, he sought confirmatory testing but was told there weren’t enough tests available for those who hadn’t had demonstrated exposure to an…
The New England Journal of Medicine: Search Results in Primary Care\Hospitalist\Clinical Practice
Wed Mar 18, 2020 02:00
Biologicals in atopic disease in pregnancy: an EAACI position paper
Abstract Biologicals have transformed the management of severe disease phenotypes in asthma, atopic dermatitis, and chronic spontaneous urticaria. As a result, the number of approved biologicals for the treatment of atopic diseases is continuously increasing. Although atopic diseases are among the most common diseases in the reproductive age, investigations, and information on half‐life, pharmacokinetics defining the neonatal Fc receptors (FcRn) and most important safety of biologicals in pregnancy...
Allergy
Thu Mar 19, 2020 11:06
Sputum and serum immunoglobulins in adult asthmatics with recurrent respiratory tract infections
Allergy
Thu Mar 19, 2020 11:06
A new look at neurobehavioral development in rhesus monkey neonates (Macaca mulatta)
Abstract The Brazelton Neonatal Behavioral Assessment Scale (NBAS) evaluates a newborn infant's autonomic, motor, state, temperament, and social‐attentional systems, which can help to identify infants at risk of developmental problems. Given the prevalence of rhesus monkeys being used as an animal model for human development, here we aimed to validate a standardized test battery modeled after the NBAS for use with nonhuman primates called the Infant Behavioral Assessment Scale (IBAS), employing...
American Journal of Primatology
Thu Mar 19, 2020 11:04
Chimpanzee ranging responses to fruit availability in a high‐elevation environment
Spatial and altitudinal variation in Nyungwe chimpanzee ranging (100% MCP) in months when diet was dominated by onespecies: (a) Ficus lutea, (b) Symphonia globulifera, (c) Podocarpus latifolius, and (d) Syzygium guineense. MCP, minimum convex polygon. Abstract Most primates experience seasonal fluctuations in the availability of food resources and face the challenge of balancing energy expenditure with energy gain during periods of resource scarcity. This is likely to be particularly challenging...
American Journal of Primatology
Thu Mar 19, 2020 11:04
Selumetinib in Children with Inoperable Plexiform Neurofibromas
New England Journal of Medicine, Ahead of Print.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:18
Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol
New England Journal of Medicine, Ahead of Print.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:08
Am I Part of the Cure or Am I Part of the Disease? Keeping Coronavirus Out When a Doctor Comes Home
New England Journal of Medicine, Ahead of Print.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:06
Case 9-2020: A 64-Year-Old Man with Shortness of Breath, Cough, and Hypoxemia
New England Journal of Medicine, Volume 382, Issue 12, Page 1150-1159, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
Essential Thrombocythemia
New England Journal of Medicine, Volume 382, Issue 12, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
Opioid Prescribing in the Midst of Crisis — Myths and Realities
New England Journal of Medicine, Volume 382, Issue 12, Page 1086-1088, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
Hereditary Angioedema
New England Journal of Medicine, Volume 382, Issue 12, Page 1136-1148, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
Community-wide Screening for Tuberculosis
New England Journal of Medicine, Volume 382, Issue 12, Page 1185-1186, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
Decision Making for Treatment of Persistent Sciatica
New England Journal of Medicine, Volume 382, Issue 12, Page 1161-1162, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
Screening and Treatment Program to Eliminate Hepatitis C in Egypt
New England Journal of Medicine, Volume 382, Issue 12, Page 1166-1174, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
New England Journal of Medicine, Ahead of Print.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
Surgery versus Conservative Care for Persistent Sciatica Lasting 4 to 12 Months
New England Journal of Medicine, Volume 382, Issue 12, Page 1093-1102, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
Retinal Detachment in X-Linked Retinoschisis
New England Journal of Medicine, Volume 382, Issue 12, Page 1149-1149, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
HIV, Pregnancy, and Isoniazid Preventive Therapy
New England Journal of Medicine, Volume 382, Issue 12, Page 1184-1185, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
Misdiagnosis, Mistreatment, and Harm — When Medical Care Ignores Social Forces
New England Journal of Medicine, Volume 382, Issue 12, Page 1083-1086, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
The Dishonesty of Informed Consent Rituals
New England Journal of Medicine, Volume 382, Issue 12, Page 1089-1091, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
Penile Kaposi’s Sarcoma
New England Journal of Medicine, Volume 382, Issue 12, March 2020.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00
SARS-CoV-2 Infection in Children
New England Journal of Medicine, Ahead of Print.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Wed Mar 18, 2020 11:00

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