Accumulated evidence revealed that aberrant CpG island hypermethylation plays important roles in carcinogenesis which can serve as a promising target for molecular detection in body fluids. Despite a myriad of attempts to diagnose ovarian cancer at an early stage, this clinical aim still remains a major challenge. To date, no single biomarker is able to accurately detect early OC in either tissue or body fluid. Aberrant DNA methylation patterns in circulating DNA provide highly specific cancer signals....
09:15
Tertiary lymphoid structures (TLSs) provide an immunological antineoplastic effect. Recent evidences link a unique 12‐chemokine (CCL2, −3, −4, −5, −8, −18, −19, −21, CXCL9, −10, −11, −13) signature status from tumor tissue and the TLS expression. However, the potential significance of 12‐chemokine signature status for clinical use is unknown. We aimed to evaluate the association of 12‐chemokine signature status with patient outcomes in colorectal cancer (CRC). We used integrated data of resected...
09:15
Rituximab‐associated infusion reactions (IRs) are significant burdens on oncology patients, caregivers, and healthcare providers. We evaluated whether montelukast and rupatadine improve rituximab delivery, decrease frequency/severity of IRs and the number of medications used to control IRs. Using a non‐randomized clinical study design we assessed adult rituximab naïve patients with B‐cell lymphoid malignancies from January 2017 to July 2019. Prior to the first rituximab infusion patients received...
Thu Mar 19, 2020 09:49
Related ArticlesNEAT1 Long Isoform Is Highly Expressed in Chronic Lymphocytic Leukemia Irrespectively of Cytogenetic Groups or Clinical Outcome. Noncoding RNA. 2020 Mar 13;6(1): Authors: Ronchetti D, Favasuli V, Monti P, Cutrona G, Fabris S, Silvestris I, Agnelli L, Colombo M, Menichini P, Matis S, Gentile M, Nurtdinov R, Guigó R, Baldini L, Fronza G, Ferrarini M, Morabito F, Neri A, Taiana E Abstract The biological role and therapeutic potential of...
Thu Mar 19, 2020 12:24
Related ArticlesSystemic treatment of advanced hepatocellular cancer: new hope on the horizon. Expert Rev Anticancer Ther. 2019 04;19(4):343-353 Authors: Chang Lee R, Tebbutt N Abstract INTRODUCTION: Hepatocellular carcinoma (HCC) is among the leading causes of cancer-related mortality in the world. The majority of the patients present at an advanced or incurable stage where neither locoregional treatment nor combination treatment of locoregional treatment...
Thu Mar 19, 2020 12:24
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου