Objectives The aims of the study were to systematically analyze causes for radiation dose outliers in emergency department noncontrast head computed tomographies (CTs), to develop and implement standardized system solutions, and audit program success for an extended period of time. Methods This study was performed in a large, tertiary academic center between January 2015 and September 2017. Four phases of radiation dose data collection with and without prior interventions were performed....
Wed Mar 11, 2020 02:00
Purpose Incomplete partition III (IP-III) characterized by congenital mixed or sensorineural hearing loss is a rare genetic disease transmitted through X-linked inheritance. Incomplete partition III can be easily achieved based on pathognomonic computed tomography findings. The aims of this study were to investigate the otic capsule abnormalities in IP-III and to report irregular contour of membranous labyrinth and hypomineralized areas at otic capsule, which have not previously been described. ...
Wed Mar 11, 2020 02:00
Objective To identify left ventricular (LV) myocardial mechanics predictors of LV outflow tract obstruction (LVOTO) in patients with hypertrophic cardiomyopathy (HCM). Methods Thirty-nine adults with HCM and 21 controls underwent cardiovascular magnetic resonance. The feature tracking (FT) analysis results of HCM patients with and without LVOTO and controls were compared. Results Global radial strain measured on the short-axis slice (GRS-SAX) (odds ratio [OR], 1.09; 95% confidence interval...
Wed Mar 11, 2020 02:00
Objectives In the present study, we investigated whether mastoid pneumatization affects facial canal dimensions and distances of facial tympanic segment and scutum, and lateral semicircular (LSS) canal and scutum. Methods One hundred sixty-one temporal multidetector computed tomography scans were reviewed. Patients with unilateral sclerotic mastoid pneumatization (no aeration) (group 1, n = 81) and unilateral total mastoid pneumatization (100.0% aeration) (group 2, n = 80) were included....
Wed Mar 11, 2020 02:00
Objective The aim of this study was to investigate if Hounsfield unit (HU) values from virtual noncontrast (VNC) images derived from portal venous phase spectral-detector computed tomography can help to differentiate adrenal adenomas and metastases. Methods Spectral-detector computed tomography datasets of 33 patients with presence of adrenal lesions and standard of reference for lesion origin by follow-up/prior examinations or dedicated magnetic resonance imaging were included. Conventional...
Wed Mar 11, 2020 02:00
Publication date: May 2020Source: Biomedicine & Pharmacotherapy, Volume 125Author(s): Bing Qian, LiJun Zhao, XiaoFang Wang, Juan Xu, Fang Teng, LingJuan Gao, Rong Shen
Thu Mar 12, 2020 12:15
Publication date: May 2020Source: Biomedicine & Pharmacotherapy, Volume 125Author(s): Guangyong Wu, Wei Wang, Yu Liu, Kai Zhuang, Tao Cai, Zhi Fei Wang, Liang Yang
Thu Mar 12, 2020 12:15
Publication date: May 2020Source: Biomedicine & Pharmacotherapy, Volume 125Author(s): Tairine Zara Lopes, Fabio Rogério de Moraes, Antonio Claudio Tedesco, Raghuvir Krishnaswamy Arni, Paula Rahal, Marilia Freitas Calmon
Thu Mar 12, 2020 12:15
Publication date: May 2020Source: Biomedicine & Pharmacotherapy, Volume 125Author(s): Zhe Wang, Wenhao Wang, Weihong Zhao, Zhilian Wang, Jing Yang, Wei Wang, Peng Teng, Xiaoqiang Su, Dongyan Li, Xi Zhang, Hui Wang, Min Hao
Thu Mar 12, 2020 12:15
Publication date: May 2020Source: Biomedicine & Pharmacotherapy, Volume 125Author(s): Mehnath Sivaraj, Arjama Mukherjee, Rajan Mariappan, Annamalai Govindhan, Jeyaraj Murugaraj
Thu Mar 12, 2020 12:15
Publication date: May 2020Source: Radiotherapy and Oncology, Volume 146Author(s): Diane Mege, Guillaume Meurette, Bertrand Trilling, Paul-Antoine Lehur, Vincent Wyart, Valérie Bridoux, Henri Damon, Elsa Lambrescak, Jean-Luc Faucheron, Igor Sielezneff, François Mion, Isabelle Etienney, Anne-Marie Leroi, Laurent Siproudhis, Charlène Brochard
Thu Mar 12, 2020 12:12
Whole Blood for Civilian Urban Trauma Resuscitation: Historical, Present, and Future Considerations.
Related ArticlesWhole Blood for Civilian Urban Trauma Resuscitation: Historical, Present, and Future Considerations. Semin Thromb Hemost. 2020 Mar;46(2):221-234 Authors: Walsh M, Fries D, Moore E, Moore H, Thomas S, Kwaan HC, Marsee MK, Grisoli A, McCauley R, Vande Lune S, Chitta S, Vyakaranam S, Waxman D, McCurdy MT, Zimmer D, Patel B, Thachil J Abstract Whole blood (WB) has been used for more than a century for far-forward combat resuscitation. Following...
Thu Mar 12, 2020 12:12
Related ArticlesAdult and cord blood-derived high affinity gB-CAR-T cells effectively react against human cytomegalovirus infections. Hum Gene Ther. 2020 Mar 11;: Authors: Olbrich H, Theobald SJ, Slabik C, Gerasch L, Schneider A, Mach M, Shum T, Mamonkin M, Stripecke R Abstract Human cytomegalovirus (HCMV) reactivations are associated with lower overall survival after transplantations. Adoptive transfer of HCMV-reactive expanded or selected T cells can...
Thu Mar 12, 2020 12:12
Related ArticlesClinical Documentation to Predict Factors Associated with Urinary Incontinence Following Prostatectomy for Prostate Cancer. Res Rep Urol. 2020;12:7-14 Authors: Li K, Banerjee I, Magnani CJ, Blayney DW, Brooks JD, Hernandez-Boussard T Abstract Background: Advances in data collection provide opportunities to use population samples in identifying risk factors for urinary incontinence (UI), which occurs in up to 71% of men with prostate cancer...
Thu Mar 12, 2020 12:12
Related ArticlesUpright Radiation Therapy-A Historical Reflection and Opportunities for Future Applications. Front Oncol. 2020;10:213 Authors: Rahim S, Korte J, Hardcastle N, Hegarty S, Kron T, Everitt S Abstract Since the early days of megavoltage Radiation Therapy (RT), the potential of delivering treatment to a sub group of patients in an upright position has been recognized. Compared to lying horizontally, treating patients in an upright position...
Thu Mar 12, 2020 12:12
Related ArticlesImmunotherapy for Non-small Cell Lung Cancer: Current Landscape and Future Perspectives. Immune Netw. 2020 Feb;20(1):e10 Authors: Lim SM, Hong MH, Kim HR Abstract Immune checkpoint inhibitors (ICIs) have shown remarkable benefit in the treatment of patients with non-small-cell lung cancer (NSCLC) and have emerged as an effective treatment option even in the first-line setting. ICIs can block inhibitory pathways that restrain the immune...
Thu Mar 12, 2020 12:12
Related ArticlesTen Years of Gabor-Domain Optical Coherence Microscopy. Appl Sci (Basel). 2019 Jun 02;9(12): Authors: Canavesi C, Rolland JP Abstract Gabor-domain optical coherence microscopy (GDOCM) is a high-definition imaging technique leveraging principles of low-coherence interferometry, liquid lens technology, high-speed imaging, and precision scanning. GDOCM achieves isotropic 2 μm resolution in 3D, effectively breaking the cellular resolution...
Thu Mar 12, 2020 12:12
Related ArticlesGlutaminase-1 (GLS1) inhibition limits metastatic progression in osteosarcoma. Cancer Metab. 2020;8:4 Authors: Ren L, Ruiz-Rodado V, Dowdy T, Huang S, Issaq SH, Beck J, Wang H, Tran Hoang C, Lita A, Larion M, LeBlanc AK Abstract Background: Osteosarcoma (OS) is a malignant bone tumor that often develops during the period of rapid growth associated with adolescence. Despite successful primary tumor control accompanied by adjuvant chemotherapy,...
Thu Mar 12, 2020 12:12
Related ArticlesCombination checkpoint inhibitors for treatment of non-small-cell lung cancer: an update on dual anti-CTLA-4 and anti-PD-1/PD-L1 therapies. Drugs Context. 2020;9: Authors: Puri S, Shafique M Abstract Immunotherapy has revolutionized cancer treatment. In non-small-cell lung cancer (NSCLC), monotherapy with immune checkpoint inhibitors has improved survival in metastatic disease. Combinations of immune checkpoint inhibitors have shown synergy...
Thu Mar 12, 2020 12:12
Related ArticlesLow Dose Prophylaxis in Hemophilia Care. Indian J Hematol Blood Transfus. 2020 Jan;36(1):16-25 Authors: Sidharthan N, Sudevan R Abstract Hemophilia is an inherited bleeding disorder which causes impaired blood clotting. The severity of disease depends on the type of Hemophilia, level of clotting factor concentrate (CFC), phenotypic heterogeneity and the development of inhibitors. The currently accepted standard of care of this disease...
Thu Mar 12, 2020 12:12
Thu Mar 12, 2020 02:00
Abstract Purpose Current screening and monitoring of prostate cancer (PCa) is insufficient, producing inaccurate diagnoses. Presence of the receptor for advanced glycation end-products (RAGE) is associated with signature characteristics of PCa development such as cell proliferation, anchorage-independent growth, angiogenesis, migration, invasion, and poor patient survival. Therefore, we developed a preclinical multimodal imaging strategy...
Thu Mar 12, 2020 02:00
Related ArticlesImpact of interlukin-6 on central obesity measures in women with polycystic ovarian syndrome. J Obstet Gynaecol. 2020 Mar 11;:1-5 Authors: Alissa EM, Algarni SA, Khaffji AJ, Al Mansouri NM Abstract Our aim was to investigate the relationship between plasma interleukin-6 (IL-6) levels with different measures of central obesity among Saudi women with and without polycystic ovarian syndrome (PCOS). One hundred and sixty-four Saudi females,...
Thu Mar 12, 2020 12:12
Related ArticlesAddressing Recent Failures in Immuno-Oncology Trials to Guide Novel Immunotherapeutic Treatment Strategies. Pharmaceut Med. 2020 Mar 10;: Authors: Nakhoda SK, Olszanski AJ Abstract The incorporation of checkpoint inhibitors into the treatment armamentarium of oncologic therapeutics has revolutionized the course of disease in many cancers. This has spurred the evaluation of other novel immunotherapy agents in clinical trials with varying...
Thu Mar 12, 2020 12:12
Related ArticlesApplication of miRNAs in the diagnosis and monitoring of testicular germ cell tumours. Nat Rev Urol. 2020 Mar 10;: Authors: Almstrup K, Lobo J, Mørup N, Belge G, Rajpert-De Meyts E, Looijenga LHJ, Dieckmann KP Abstract Testicular germ cell tumours (TGCTs) are the most frequent cancer type in young men and originate from the common precursor germ cell neoplasia in situ (GCNIS). For decades, clinical management of patients with TGCT has...
Thu Mar 12, 2020 12:12
Related ArticlesBRD4 levels determine the response of human lung cancer cells to BET degraders that potently induce apoptosis through suppression of Mcl-1. Cancer Res. 2020 Mar 10;: Authors: Zong D, Gu J, Cavalcante GC, Yao W, Zhang G, Wang S, Owonikoko TK, He X, Sun SY Abstract Lung cancer consists of approximately 80% non-small cell lung cancer (NSCLC) and 20% small cell lung cancer (SCLC) and remains the leading cause of cancer deaths worldwide despite...
Thu Mar 12, 2020 12:12
Related ArticlesImmunotherapy for metastatic cancer patients: the current status, limitations, obstacles and future directions. Ann Palliat Med. 2020 Mar 05;: Authors: Yau SH PMID: 32156134 [PubMed - as supplied by publisher]
Thu Mar 12, 2020 12:12
Related ArticlesTumor treating fields in neuro-oncology: integration of alternating electric fields therapy into promising treatment strategies. Chin Clin Oncol. 2020 Feb 29;: Authors: Berger TR, Wong ET Abstract As the most recent innovation in cancer therapy that utilizes properties of the electromagnetic spectrum, tumor treating fields (TTFields) are non-invasive alternating electrical fields that target rapidly dividing tumor cells. In the patient,...
Thu Mar 12, 2020 12:12
Related ArticlesImmune Checkpoint Inhibitors in Epithelial Ovarian Cancer: An Overview on Efficacy and Future Perspectives. Diagnostics (Basel). 2020 Mar 07;10(3): Authors: Borella F, Ghisoni E, Giannone G, Cosma S, Benedetto C, Valabrega G, Katsaros D Abstract Epithelial ovarian cancer (EOC) is the leading cause of death among gynecological cancers. Despite improvements in medical treatments, the prognosis for EOC remains poor, and there is an urgent...
Thu Mar 12, 2020 12:12
Related ArticlesMitochondrial Epigenetics: Non-Coding RNAs as a Novel Layer of Complexity. Int J Mol Sci. 2020 Mar 06;21(5): Authors: Cavalcante GC, Magalhães L, Ribeiro-Dos-Santos Â, Vidal AF Abstract Mitochondria are organelles responsible for several functions involved in cellular balance, including energy generation and apoptosis. For decades now, it has been well-known that mitochondria have their own genetic material (mitochondrial DNA), which...
Thu Mar 12, 2020 12:12
Related ArticlesFruit and Vegetable Consumption and Sarcopenia among Older Adults in Low- and Middle-Income Countries. Nutrients. 2020 Mar 06;12(3): Authors: Koyanagi A, Veronese N, Solmi M, Oh H, Shin JI, Jacob L, Yang L, Haro JM, Smith L Abstract Fruit and vegetable consumption may protect against sarcopenia but there are no studies on this topic from low- and middle-income countries (LMICs). Thus, we assessed this association among older adults from...
Thu Mar 12, 2020 12:12
Related ArticlesPrognostic Value of Lymph Node-To-Primary Tumor Standardized Uptake Value Ratio in Esophageal Squamous Cell Carcinoma Treated with Definitive Chemoradiotherapy. Cancers (Basel). 2020 Mar 06;12(3): Authors: Lin CH, Hung TM, Chang YC, Hsieh CH, Shih MC, Huang SM, Yang CK, Chang CF, Chan SC, Yap WK Abstract We aimed to investigate the prognostic value of the relative maximum standardized uptake value (SUV) of metastatic lymph node (LN) compared...
Thu Mar 12, 2020 12:12
Related ArticlesSurvivorship Science at the NIH: Lessons Learned From Grants Funded in Fiscal Year 2016. J Natl Cancer Inst. 2019 02 01;111(2):109-117 Authors: Rowland JH, Gallicchio L, Mollica M, Saiontz N, Falisi AL, Tesauro G Abstract Federal investment in survivorship science has grown markedly since the National Cancer Institute's creation of the Office of Cancer Survivorship in 1996. To describe the nature of this research, provide a benchmark,...
Thu Mar 12, 2020 12:12
Publication date: Available online 12 March 2020Source: TalantaAuthor(s): Cristina Malegori, Eugenio Alladio, Paolo Oliveri, Cristina Manis, Marco Vincenti, Paolo Garofano, Filippo Barni, Andrea Berti
Thu Mar 12, 2020 12:12
Publication date: Available online 12 March 2020Source: TalantaAuthor(s): Zuzanna Małyjurek, Raffaele Vitale, Beata Walczak
Thu Mar 12, 2020 12:12
Publication date: Available online 12 March 2020Source: TalantaAuthor(s): Yanyan Zhang, Joann K. Whalen, Sung Vo Duy, Gabriel Munoz, Barry R. Husk, Sébastien Sauvé
Thu Mar 12, 2020 12:12
Publication date: Available online 12 March 2020Source: TalantaAuthor(s): Elif Burcu Aydın
Thu Mar 12, 2020 12:12
Publication date: Available online 12 March 2020Source: TalantaAuthor(s): Piotr Sosnowski, Gérard Hopfgartner
Thu Mar 12, 2020 12:12
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