Related ArticlesRadiation Induced Demyelination in Cervical Spinal Cord of the Head and Neck Cancer Patients after Receiving Radiotherapy. J Biomed Phys Eng. 2020 Feb;10(1):1-6 Authors: H G, N S, O P G, R K T Abstract Background: Cervical spinal cord is important and radiosensitive. It is the most critical organ for the head and neck (H&N) cancer patients during radiotherapy. If the delivered dose to the cord is more than tolerance dose, demyelination...
Related ArticlesBilateral Bone Anchored Hearing aids: A Case Report on Right Side Percutaneous and Left Side Transcutaneous Implant. Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):148-151 Authors: Vadlamani S, Kumar A, Gaur SK, Dutt SN, Kameswaran M Abstract Bilateral Bone Anchored Hearing Aids (BAHA) provide more subjective patient satisfaction and outcome than unilateral BAHA. Initially, percutaneous BAHAs were used for many decades. Transcutaneous...
Related ArticlesPleomorphic Adenoma of Tongue: A Case Report. Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):145-147 Authors: Sarma M, Sahoo SR Abstract Pleomorphic adenoma (PA) of minor salivary glands accounts for less than 3% of all head and neck tumors. It is a benign tumor. Palate is the most common site followed by upper lips. Tongue is an unusual site. We present a case report of a 35-year-old male patient who presented with a mass in...
Related ArticlesPrognostic Value of Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Head and Neck Malignancies. Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):128-132 Authors: Seetohul YB, Singh V, Jain RK, Chaudhary AK Abstract To study the prognostic significance of neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) in head and neck cancers. The study included 170 cases of histopathologically diagnosed head...
Related ArticlesA Study on the Prevalence and Clinical Features of Fungal Sinusitis in Chronic Rhinosinusitis. Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):117-122 Authors: Shetty S, Chandrashekar S, Aggarwal N Abstract Chronic sinusitis is a common disorder worldwide a significant proportion of which is secondary to fungal aetiology contrary to popular belief that fungal sinusitis is a rare entity, more so in a country like India where warm...
Related ArticlesCorrelation Between Microbiological Profiles of Adenoid Tissue and Nasal Discharge in Children with Co-existent Chronic Adenoiditis and Chronic Rhinosinusitis. Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):112-116 Authors: Singh R, Shilpa R, Mukhopadhyay C, Shenoy PA, Balakrishnan R, Devaraja K Abstract Chronic adenoiditis leading to adenoid hypertrophy is common in children. Many cases would also have co-existing chronic rhinosinusitis...
Related ArticlesRobotic Surgery in Head and Neck in Pediatric Population: Our Experience. Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):98-103 Authors: Venkatakarthikeyan C, Nair S, Gowrishankar M, Rao S Abstract Robot assisted surgery of the head and neck is a relatively novel approach in the management of head and neck tumors. There are very few reported cases of robot-assisted surgery of the head and neck in pediatric population in the world...
Related ArticlesMasseteric-Facial Nerve Anastomosis: Surgical Techniques and Outcomes-A Pilot Indian study. Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):92-97 Authors: Sakthivel P, Singh CA, Thakar A, Thirumeni G, Raveendran S, Sharma SC Abstract Masseteric-facial anastomosis has gained popularity in recent days compared to the facial-hypoglossal anastomosis. Masseteric nerve has numerous advantages like its proximity to the facial nerve,...
Related ArticlesA Prospective Study on Temporal Bone Involvement in Polytrauma Patients and the Effect of Early Diagnosis on Hearing Loss. Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):30-35 Authors: Padmakumar V, Ramesh Kumar E, Ramakrishnan VR Abstract As polytrauma cases are on the rise, a large number of patients presents with temporal bone fractures, which can result in various types of injuries varying from trivial to more serious injuries....
Related ArticlesUse of Clavien-Dindo Classification System in Assessing Head and Neck Surgery Complications. Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):24-29 Authors: Vallur S, Dutta A, Arjun AP Abstract Improving quality of postoperative surgical care in head and neck surgery requires reporting of complications. Clavien-Dindo classification system can be used in grading complications related to head and neck surgery and to assess interobserver...
Related ArticlesThe Association of IL-1 Alpha Level and TNF Alpha Expressions on Bone Destruction in Chronic Suppurative Otitis Media and Cholesteatoma. Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):1-7 Authors: Artono, Surarto B, Purnami N, Hutahaen F, Mahardhika MR Abstract Bone destruction in patients with chronic suppurative otitis media (CSOM) and cholesteatoma is considered to be quite high. Bone destruction is caused by various inflammatory...
Related ArticlesActivity of platinum and cetuximab in cutaneous squamous cell cancer not amenable to curative treatment. Drugs Context. 2019;8:212611 Authors: Galbiati D, Cavalieri S, Alfieri S, Resteghini C, Bergamini C, Orlandi E, Platini F, Locati L, Giacomelli L, Licitra L, Bossi P Abstract Background: Unresectable or metastatic cutaneous squamous cell cancers (cSCCs) are rare but potentially life-threatening diseases. In this setting, systemic...
Related ArticlesRelationship between serum inhibitory activity for IgE and efficacy of Artemisia pollen subcutaneous immunotherapy for allergic rhinitis: a preliminary self-controlled study. Allergy Asthma Clin Immunol. 2020;16:18 Authors: Wang W, Yin J, Wang X, Ma T, Lan T, Song Q, Guo Y Abstract Background: Biomarkers of clinical efficacy for subcutaneous immunotherapy (SCIT) on allergic rhinitis (AR) have not been identified yet. This study aims...
Related ArticlesBrain Abscess as a Rare Complication of Primary Extranodal Nasal-type Natural Killer/T-cell Lymphoma. Yonago Acta Med. 2020 Feb;63(1):88-91 Authors: Ohta N, Waki T, Ito T, Suzuki Y, Kakehata S, Aoyagi M Abstract We present the case of a 58-year-old Japanese woman with a natural killer T (NK/T)-cell lymphoma complicated by brain abscess. NK/T-cell lymphomas represent a rare type of lymphoma derived from either activated NK cells or,...
Related ArticlesImpact of Screening for Salivary Gland by Ultrasonography. Yonago Acta Med. 2020 Feb;63(1):42-46 Authors: Onda K, Fukuhara T, Matsuda E, Donishi R, Hirooka Y, Takeuchi H, Kato M Abstract Background: Ultrasonography is superior to other imaging modalities for detecting salivary gland diseases. However, there have been no reports of the results of salivary gland screening with ultrasonography. In this study, the salivary glands were...
Related ArticlesProgression of Thyroid Carcinoma Is Promoted by the m6A Methyltransferase METTL3 Through Regulating m6A Methylation on TCF1. Onco Targets Ther. 2020;13:1605-1612 Authors: Wang K, Jiang L, Zhang Y, Chen C Abstract Objective: This study aims to uncover the progression of thyroid carcinoma influenced by the m6A methyltransferase METTL3 through regulating m6A methylation on TCF1 mRNA and the activated Wnt pathway. Methods: Thyroid...
Related ArticlesTherapeutic Potential of Dupilumab in the Treatment of Chronic Rhinosinusitis with Nasal Polyps: Evidence to Date. Ther Clin Risk Manag. 2020;16:31-37 Authors: Kim J, Naclerio R Abstract Chronic rhinosinusitis with nasal polyposis (CRSwNP) is one of the most severe forms of chronic rhinosinusitis. CRSwNP is characterized by nasal and facial congestion, loss of sense of smell, rhinorrhea, and post-nasal drip. Treatments have been ineffective...
Related ArticlesFisetin Modulates Human Oral Squamous Cell Carcinoma Proliferation by Blocking PAK4 Signaling Pathways. Drug Des Devel Ther. 2020;14:773-782 Authors: Li Y, Jia S, Dai W Abstract Objective: Human oral squamous cell carcinoma (OSCC) is a major cause of mortality and morbidity worldwide. There is an urgent need to identify bioactive molecules and potential target genes that could inhibit carcinogenesis for OSCC therapy. Fisetin (3,7,3',4'-tetrahydroxyflavone),...
Related ArticlesA goitrous model for Bartolomeo Vivarini (1432-1499). J Endocrinol Invest. 2020 Mar 10;: Authors: Accorona R, Torretta S, Pignataro L Abstract INTRODUCTION: Bartolomeo Vivarini (Venezia 1432c.-Venezia 1499c.) was an Italian painter during the Renaissance. The artist was widely influenced by Andrea Mantegna, whose opera was characterized by personages with anatomical details meticulously described. MATERIALS AND METHODS:...
Related ArticlesRadiotherapy planning techniques to reduce lung irradiation in head and neck cancer patients with mediastinal involvement. Radiol Phys Technol. 2020 Mar 10;: Authors: Kawamura M, Yoshimura M, Nakamura M, Ishihara Y, Mukumoto N, Hirashima H, Iramina H, Hiraoka M, Mizowaki T Abstract The number of patients with head and neck squamous cell carcinoma (HNC) with mediastinal involvement is small, and appropriate treatment techniques have...
Related ArticlesIdentification of extracellular vesicles-transported miRNAs in Erlotinib-resistant head and neck squamous cell carcinoma. J Cell Commun Signal. 2020 Mar 10;: Authors: Zheng Y, Song A, Zhou Y, Zhong Y, Zhang W, Wang C, Ding X, Du Y, Zhang W, Li G, Wu H, Wu Y, Song X Abstract Erlotinib is an oral tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR) pathway. Although our previous study has proved the efficacy of Erlotinib...
Related ArticlesSurgical Training Throughout Africa: A Review of Operative Case Volumes at Multiple Training Centers. World J Surg. 2020 Mar 10;: Authors: Parker RK, Topazian HM, Ndegwa W, Chesang P, Strain S, Thelander K, Parker AS, Riviello R Abstract BACKGROUND: Adequate surgical training is paramount to produce competent surgeons to address the global burden of surgical disease. The Pan-African Academy of Christian Surgeons (PAACS) has general...
Related Articles[Continuous intraoperative neuromonitoring (cIONM) in head and neck surgery-a review. German version]. HNO. 2020 Mar 10;: Authors: Stankovic P, Wittlinger J, Georgiew R, Dominas N, Hoch S, Wilhelm T Abstract Although the history of intraoperative neuromonitoring (IONM) dates back to the 19th century, the method did not evolve further than the mere differentiation of nerves until recently. Only the development of continuous IONM (cIONM)...
Related ArticlesThe Alcohol Use Disorders Identification Test and the risk of metachronous cancer after endoscopic resection of esophageal cancer. Carcinogenesis. 2020 Mar 11;: Authors: Yokoyama A, Katada C, Yokoyama T, Takizawa K, Yano T, Oda I, Shimizu Y, Nakanishi H, Koike T, Hirao M, Okada H, Yoshii T, Katagiri A, Yamanouchi T, Matsuo Y, Kawakubo H, Kobayashi N, Ishikawa H, Muto M Abstract Follow-up studies of Japanese patients who had undergone...
Related ArticlesRadiation resistance in head and neck squamous cell carcinoma: dire need for an appropriate sensitizer. Oncogene. 2020 Mar 10;: Authors: Hutchinson MND, Mierzwa M, D'Silva NJ Abstract Radiation is a significant treatment for patients with head and neck cancer. Despite advances to improve treatment, many tumors acquire radiation resistance resulting in poor survival. Radiation kills cancer cells by inducing DNA double-strand breaks....
Related ArticlesAn Engineered Three-Dimensional Stem Cell Niche in the Inner Ear by Applying a Nanofibrillar Cellulose Hydrogel with a Sustained-Release Neurotrophic Factor Delivery System. Acta Biomater. 2020 Mar 07;: Authors: Chang HT, Heuer RA, Oleksijew AM, Coots KS, Roque CB, Nella KT, McGuire TL, Matsuoka AJ Abstract Although the application of human embryonic stem cells (hESCs) in stem cell-replacement therapy remains promising, its potential...
Related ArticlesThe effect of maxillary advancement on articulation of alveolar consonants in cleft patients. J Craniomaxillofac Surg. 2020 Feb 14;: Authors: Alaluusua S, Harjunpää R, Turunen L, Geneid A, Leikola J, Heliövaara A Abstract INTRODUCTION: Maxillary advancement may affect speech in cleft patients. The aim of this study was to evaluate the effect of maxillary advancement on Finnish alveolar consonants /s/, /l/, and /r/ in cleft patients....
Related ArticlesEvaluating Safety of Awake, Bilateral Injection Laryngoplasty for Bilateral Vocal Fold Atrophy. J Voice. 2020 Mar 07;: Authors: Kelly Z, Patel AK, Klein AM Abstract OBJECTIVE: Office-based injection laryngoplasty (IL) has emerged as a useful procedure for otolaryngologists to correct glottic insufficiency while avoiding the costs and risks of general anesthesia. This is the first study focused on addressing the safety of bilateral...
Related ArticlesStaining efficacy assessment of a differential routine and special stains for pathological stromal calcifications in maxillofacial lesions. J Histotechnol. 2020 Mar 10;:1-7 Authors: Shefali, Sethi A, Tandon A, Shetty DC, Juneja S Abstract Head and neck connective tissue lesions may have diverse calcifications within the fibrous connective tissue stroma. The perplexity involved in the identification and determination of the nature...
Related ArticlesDiagnostic Performance of a Combination of Shear Wave Elastography and B-Mode Ultrasonography in Differentiating Benign from Malignant Thyroid Nodules. Clin Exp Otorhinolaryngol. 2020 Mar 11;: Authors: Yeon EK, Sohn YM, Seo M, Kim EJ, Eun YG, Park WS, Yun SJ Abstract Objectives.: This study was conducted to compare clinicopathologic and radiologic factors between benign and malignant thyroid nodules and to evaluate the diagnostic...
Related ArticlesMachine Learning Models for Predicting Hearing Prognosis in Unilateral Idiopathic Sudden Sensorineural Hearing Loss. Clin Exp Otorhinolaryngol. 2020 Mar 12;: Authors: Park KV, Oh KH, Jeong YJ, Rhee J, Han MS, Han SW, Choi J Abstract Objectives.: Prognosticating idiopathic sudden sensorineural hearing loss (ISSNHL) is an important challenge. In our study, a dataset was split into training and test sets and cross-validation was implemented...
Clinical Significance of Cytoplasmic IgE-Positive Mast Cells in Eosinophilic Chronic Rhinosinusitis.
Related ArticlesClinical Significance of Cytoplasmic IgE-Positive Mast Cells in Eosinophilic Chronic Rhinosinusitis. Int J Mol Sci. 2020 Mar 07;21(5): Authors: Gion Y, Okano M, Koyama T, Oura T, Nishikori A, Orita Y, Tachibana T, Marunaka H, Makino T, Nishizaki K, Sato Y Abstract Cross-linking of antigen-specific IgE bound to the high-affinity IgE receptor (FcεRI) on the surface of mast cells with multivalent antigens results in the release of mediators...
Related ArticlesNeutrophil-To-Lymphocyte and Platelet-To-Lymphocyte Ratios as Prognostic Markers of Survival in Patients with Head and Neck Tumours-Results of a Retrospective Multicentric Study. Int J Environ Res Public Health. 2020 Mar 07;17(5): Authors: Szilasi Z, Jósa V, Zrubka Z, Mezei T, Vass T, Merkel K, Helfferich F, Baranyai Z Abstract BACKGROUND: The neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) may be useful...
Related ArticlesRadiotherapy Is Associated with an Accelerated Risk of Ischemic Stroke in Oral Cavity Cancer Survivors after Primary Surgery. Cancers (Basel). 2020 Mar 06;12(3): Authors: Kuan FC, Lee KD, Huang SF, Chen PT, Huang CE, Wang TY, Chen MC Abstract The number of oral cavity carcinoma (OCC) survivors continues to increase due to advances in definitive surgery and radiation therapy (RT), however the risk of ischemic stroke is unclear in long-term...
Related ArticlesHuman Tonsil-Derived Mesenchymal Stromal Cells Maintain Proliferating and ROS-Regulatory Properties via Stanniocalcin-1. Cells. 2020 Mar 06;9(3): Authors: Seo Y, Shin TH, Ahn JS, Oh SJ, Shin YY, Yang JW, Park HY, Shin SC, Kwon HK, Kim JM, Sung ES, Park GC, Lee BJ, Kim HS Abstract Mesenchymal stromal cells (MSCs) from various sources exhibit different potential for stemness and therapeutic abilities. Recently, we reported a unique...
Related ArticlesAnatomical and Clinical Implications in Neocondyle Stability After a Condylectomy. J Craniofac Surg. 2020 Jan/Feb;31(1):241-250 Authors: Nelke KH, Morawska-Kochman M, Nienartowicz J, Grzelak J, Staszak K, Frączek M, Łuczak K, Guziński M Abstract : A condylectomy of the mandibular condyle is considered to be the treatment of choice in most cases of condylar head hyperactivity. The aim of the procedure is to remove the growth center of...
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Abstract Lysine acetyltransferases (KATs) are a highly diverse group of epigenetic enzymes that play important roles in various cellular processes including transcription, signal transduction, and cellular metabolism. However, our knowledge of the genomic and transcriptomic alterations of KAT genes and their clinical significance in human cancer remains incomplete. We performed a metagenomic analysis of 37 KATs in more than 10,000 cancer samples across 33 tumor types, focusing on breast cancer....
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Objectives. In this study, a clear aligner was moved at intervals of 0.25 mm and pressure variations were assessed using a sensor. Methods. The model used for producing the clear aligner was created using a 3-dimensional printer. A clear, circular thermoplastic of 0.75 mm thickness was used for making the clear aligner using the vacuum forming method. A pressure sensor was used to assess the pressure in the device, and the variation in the sheet pressure was statistically analyzed tooth movement...
Background. Abdominal wall weakness occurs when the strength of muscle decreases due to physiological reason or iatrogenic injury. However, the treatment of this disease is complicated. Aim. To study the therapeutic effect of acellular tissue matrix (ACTM), compared with the polypropylene mesh. Methods. An abdominal wall weakness model was established in rabbits through motor nerves cutting. The polypropylene mesh and ACTM were implanted in the left and right abdomen sides, respectively. Mechanical...
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