New Findings What is the central question of this study? The mechanisms underlying impaired muscular endurance and accelerated fatigue during acute hypoxia are incompletely understood. Hypoxia may affect neuromuscular transmission and the muscle membrane, slowing the propagation of myopotentials, compromising excitation‐contraction coupling and resulting in premature fatigue What is the main finding and its importance? Hypoxia had no effect on the electrochemical latency associated...
Thu Mar 05, 2020 23:45
New Findings What is the central question of this study? Can remote liver ischemic preconditioning(RLIPC) protect rat brain against cerebral ischemia/reperfusion injury? What is the main finding and its importance? Pretreatment with RLIPC reduced cerebral infarct volume, improved neurological outcomes and inhibited neuron apoptosis. RLIPC led to increased phosphorylation of AKT, while inhibition of AKT abolished effects of RLIPC. Our data suggest that Liver ischemic preconditioning...
Thu Mar 05, 2020 23:45
Since the 1990s, increasing numbers of Coptic Orthodox Christians have immigrated to the United States particularly through the Diversity Visa, or Green Card Lottery. In recent years, mainstream and Christian media sources as well as Copts viewed this migration as a response to the increase in attacks and persecution against Middle Eastern Christians, especially by ISIS. [pquote] Copts encounter the same sort of targeted profiling and hate crimes as do their American Muslim counterparts....
Thu Mar 05, 2020 22:30
The Ancestors Project offers a model for how section leaders can do the much-needed work of challenging sexism and white supremacy in anthropology. All eyes were glued to the speaker at the podium. Sitting and standing as closely as we would on a rush hour bus, amidst an attentive silence that wasn’t sleepy, but electric, we listened. Taking turns at the podium weren’t celebrities or heads of state, but anthropologists who were doing things differently. Capturing our attention was The Ancestors...
Thu Mar 05, 2020 18:30
Preservation and dissemination of data are at the heart of efforts to digitize and make accessible collections of legacy data from archaeological excavations. Despite the vast amount of fieldwork that is conducted each year, reports and data are often filed away for safekeeping and remain inaccessible to those without the means to access this information. Artifacts and field records from early excavations were often dispersed among projects’ various stakeholders, a consequence of the collaborative...
Thu Mar 05, 2020 16:30
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00164
Thu Mar 05, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00224
Thu Mar 05, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00358
Thu Mar 05, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b05270
Thu Mar 05, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b05095
Thu Mar 05, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b05388
Thu Mar 05, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b05607
Thu Mar 05, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b05723
Thu Mar 05, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00888
Thu Mar 05, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00506
Thu Mar 05, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00440
Thu Mar 05, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00143
Thu Mar 05, 2020 07:00
Key points The vagus nerve has been implicated in mediating behavioral effects of the gut microbiota on the central nervous system. This study examined whether the secretory products of commensal gut bacteria can modulate the excitability of vagal afferent neurons with cell bodies in nodose ganglia. Cysteine proteases from commensal bacteria increased the excitability of vagal afferent neurons via activation of protease‐activated receptor 2 and modulation of the voltage‐dependence of Na+ conductance...
Thu Mar 05, 2020 23:12
Key points While it has been well described that prolonged rotational stepping will adapt the podokinetic sense of rotation, the mechanisms involved are not clearly understood. By studying podokinetic after‐rotations following conditioning rotations not previously reported we have shown that slower rotational velocities are more readily adapted than faster velocities and adaptation occurs more quickly than previously thought. We propose a dynamic feedback model of vestibular and podokinetic...
Thu Mar 05, 2020 23:12
In the United States sudden cardiac death (SCD) claims 325,000 lives every year. SCDs are due to abnormalities in the conducting system of the cardiac tissue, resulting in arrhythmias, and can often occur after cardiac surgeries and other treatments. SCDs are medical emergencies, as cardiopulmonary resuscitation and defibrillation must be administered as soon as possible. Unfortunately, SCDs have a high mortality rate because they don’t always occur in settings with readily available medical assistance....
Thu Mar 05, 2020 22:25
Researchers at Rutgers University have developed a robot that utilizes artificial intelligence, along with near-infrared and ultrasound imaging, to automatically make blood draws and insert catheters in small blood vessels. The device could take the guesswork out of blood draws, which are frequently challenging when performed manually, and reduce the chances of complications, while allowing medical staff to focus on other tasks. Accessing blood vessels can be challenging in a wide variety...
Thu Mar 05, 2020 16:52
Foreword. In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information by sharing relevant background and reasoning with the reader (regular type). The authors’ commentary follows. Stage. A 64-year-old man…
Thu Mar 05, 2020 02:00
The vision of the End TB strategy of the World Health Organization (WHO) is of a world free of tuberculosis by the year 2035. However, extensively drug-resistant (XDR) tuberculosis (i.e. tuberculosis with resistance to isoniazid, rifampin, any fluoroquinolone, and at least one injectable drug…
Thu Mar 05, 2020 02:00
Since the discovery of the first antituberculosis drugs 75 years ago, the pursuit of a short, effective, and affordable regimen that has acceptable side effects and is capable of curing most patients most of the time has been a major public health priority. Such a "pan-tuberculosis" regimen is seen…
Thu Mar 05, 2020 02:00
The rapid spread of SARS-CoV-2, a novel coronavirus that emerged in late 2019, and the resulting Covid-19 disease has been labeled a Public Health Emergency of International Concern by the World Health Organization. What physicians need to know about transmission, diagnosis, and treatment is the…
Thu Mar 05, 2020 02:00
On December 31, 2019, China reported a cluster of cases of pneumonia in people associated with the Huanan Seafood Wholesale Market in Wuhan, Hubei Province. On January 7, 2020, Chinese health authorities confirmed that this cluster was associated with a novel coronavirus, 2019-nCoV. Although cases…
Thu Mar 05, 2020 02:00
Publication date: Available online 5 March 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Pu Han, Houpu Yang, Miao Liu, Lin Cheng, Siyuan Wang, Fuzhong Tong, Peng Liu, Bo Zhou, Yingming Cao, Hongjun Liu, Chaobin Wang, Yuan Peng, Danhua Shen, Shu Wang
Thu Mar 05, 2020 21:51
Publication date: Available online 4 March 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Leah Drost, Kullervo Hynynen, Yuexi Huang, Benjamin Lucht, Erin Wong, Gregory Czarnota, Caitlin Yee, Bo Angela Wan, Vithusha Ganesh, Edward Chow, Elizabeth David
Thu Mar 05, 2020 21:51
Publication date: Available online 4 March 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Salim Harris, Al Rasyid
Thu Mar 05, 2020 21:51
Publication date: 15 May 2020Source: Behavioural Brain Research, Volume 385Author(s): Estefanía González-Morales, Gabriela Rodríguez-Manzo
Thu Mar 05, 2020 21:35
This protocol describes a comprehensive hemocompatibility evaluation of blood-contacting devices using laser-cut neurovascular implants. A flow loop model with fresh, heparinized human blood is applied to mimic blood flow. After perfusion, various hematologic markers are analyzed and compared to the values gained directly after blood collection for hemocompatibility evaluation of the tested devices.
Thu Mar 05, 2020 21:00
We present a protocol for evaluating the electromechanical effects of GtACR1 activation in rabbit cardiomyocytes. We provide detailed information on cell isolation, culturing and adenoviral transduction, and on functional experiments with the patch-clamp and carbon-fiber techniques.
Thu Mar 05, 2020 20:00
This article describes how to perform sexual behavior tests in male mice.
Thu Mar 05, 2020 19:00
Thu Mar 05, 2020 16:20
Objective. Myofibroblast transformation has been shown to be associated with the reactive oxygen species- (ROS-) producing enzyme NADPH oxidase (Nox4). Inhibition of transient receptor potential channel canonical type 3 (TRPC3) attenuates mitochondrial calcium handling and ROS production in the vasculature of hypertensive rats. However, it remains elusive whether TRPC3 regulates mitochondrial calcium and ROS production and participates in myofibroblast transdifferentiation during wound healing. Methods...
Thu Mar 05, 2020 16:20
Thu Mar 05, 2020 20:39
Wide–band gap metal halide perovskites are promising semiconductors to pair with silicon in tandem solar cells to pursue the goal of achieving power conversion efficiency (PCE) greater than 30% at low cost. However, wide–band gap perovskite solar cells have been fundamentally limited by photoinduced phase segregation and low open-circuit voltage. We report efficient 1.67–electron volt wide–band gap perovskite top cells using triple-halide alloys (chlorine, bromine, iodine) to tailor the band gap...
Thu Mar 05, 2020 20:39
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου