Παρασκευή 16 Αυγούστου 2019

Reviews 

Chromosomal Instability in Tumor Initiation and Development
Duc-Hiep Bach et al.

Microenvironmental Metabolism Regulates Antitumor Immunity
Verra M. Ngwa et al.

Cancer Research Highlights

Precision Therapy for Aggressive Endometrial Cancer by Reactivation of Protein Phosphatase 2A
Kaitlin Haines et al.

Controversy and Consensus

Connecting Students with Patients and Survivors to Enhance Cancer Research Training
Robert N. Riter et al.

Molecular Cell Biology

MYC Regulates the HIF2α Stemness Pathway via Nanog and Sox2 to Maintain Self-Renewal in Cancer Stem Cells versus Non-Stem Cancer Cells
Bikul Das et al.

Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine Gliomas
Robert F. Koncar et al.

AuthorChoice The Pro-Oncogenic Adaptor CIN85 Acts as an Inhibitory Binding Partner of Hypoxia-Inducible Factor Prolyl Hydroxylase 2
Nina Kozlova et al.

ID1 Is Critical for Tumorigenesis and Regulates Chemoresistance in Glioblastoma
Rohit Sachdeva et al.

Isoflavone ME-344 Disrupts Redox Homeostasis and Mitochondrial Function by Targeting Heme Oxygenase 1
Leilei Zhang et al.

TRIM67 Activates p53 to Suppress Colorectal Cancer Initiation and Progression
Shiyan Wang et al.

AuthorChoice Recycling Endosomes in Mature Epithelia Restrain Tumorigenic Signaling
Luca D'Agostino et al.

Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models
Anna-Mariya Kukuyan et al.

Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression
Cai Bowen et al.

p38 Stabilizes Snail by Suppressing DYRK2-Mediated Phosphorylation That Is Required for GSK3β-βTrCP–Induced Snail Degradation
Ki-Jun Ryu et al.



Tumor Biology and Immunology

AuthorChoice Remodeling the Tumor Microenvironment Sensitizes Breast Tumors to Anti-Programmed Death-Ligand 1 Immunotherapy
Renee Clift et al.

NOTCH Signaling via WNT Regulates the Proliferation of Alternative, CCR2-Independent Tumor-Associated Macrophages in Hepatocellular Carcinoma
Yu-Chen Ye et al.

AuthorChoice EN1 Is a Transcriptional Dependency in Triple-Negative Breast Cancer Associated with Brain Metastasis
Guillermo Peluffo et al.

Deletion of the Miz-1 POZ Domain Increases Efficacy of Cytarabine Treatment in T- and B-ALL/Lymphoma Mouse Models
Julie Ross et al.

Activation of the VEGFC/VEGFR3 Pathway Induces Tumor Immune Escape in Colorectal Cancer
Carlotta Tacconi et al.

Sphingosine Kinase 1 Signaling Promotes Metastasis of Triple-Negative Breast Cancer
Sunil Acharya et al.

Transcriptomic Differences between Primary Colorectal Adenocarcinomas and Distant Metastases Reveal Metastatic Colorectal Cancer Subtypes
Yasmin Kamal et al.

The Highly Recurrent PP2A Aα-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis
Sarah E. Taylor et al.

Translational Science

Chromosome 12p Amplification in Triple-Negative/BRCA1-Mutated Breast Cancer Associates with Emergence of Docetaxel Resistance and Carboplatin Sensitivity
Jorge Gómez-Miragaya et al.

A Peptide Probe Enables Photoacoustic-Guided Imaging and Drug Delivery to Lung Tumors in K-rasLA2 Mutant Mice
Hyunkyung Jung et al.

ATP-Competitive Inhibitors Midostaurin and Avapritinib Have Distinct Resistance Profiles in Exon 17–Mutant KIT
Beth Apsel Winger et al.

Convergence and Technologies

Toward Personalized Computer Simulation of Breast Cancer Treatment: A Multiscale Pharmacokinetic and Pharmacodynamic Model Informed by Multitype Patient Data
Xiaoran Lai et al.

Editor's Notes

Free Article Editor's Note: Toll-Like Receptors on Tumor Cells Facilitate Evasion of Immune Surveillance
Bo Huang et al.

Free Article Editor's Note: Listeria monocytogenes Promotes Tumor Growth via Tumor Cell Toll-Like Receptor 2 Signaling
Bo Huang et al.

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