Abstract Background Digestive endoscopies must be performed within a safe and comfortable environment. We have previously shown that the quality of intravenous sedation is influenced by preoperative stress. Aim Our primary objective was to compare the effects of oral lorazepam and placebo on the salivary cortisol response of children undergoing a digestive...
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Related ArticlesA pilot study of first-line olaratumab, doxorubicin and ifosfamide in patients with metastatic soft tissue sarcoma. Cancer Chemother Pharmacol. 2019 Aug 13;: Authors: Vornicova O, Haim N, Bar-Sela G Abstract INTRODUCTION: Olaratumab (O) is a monoclonal antibody that specifically binds PDGFRα. The addition of O to doxorubicin (D) has been approved by the regulatory authorities for metastatic soft tissue sarcoma (MSTS). Since the combination...
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Abstract The surgical approach for hypophysectomy has undergone sweeping revolution in the past three decades. With the advent of endoscopes, better instrumentation, better illumination and viewing cameras, endoscopic endo-nasal trans-sphenoidal approach to sella has now largely become the norm. The aim of this study is to present our experience, analysing the surgical outcomes of this approach in patients with pituitary adenoma, pertaining to entirety of tumor removal, alleviation...
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Abstract The role of otolaryngologist in the management of CSF rhinorrhea is expanding. It is prudent to evaluate all cases of CSF leak, understand the etiological causes and formalize a working approach to management of such cases to yield better outcome. A retrospective descriptive study of 39 cases of proven CSF rhinorrhea treated at a tertiary care center between January 2014 to August 2019. The data retrieved were analyzed for age, gender, weight, etiology, recurrence of the...
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Abstract Septal correction is the commonest surgery by rhinologists worldwide. We aimed at studying the comfort level of the patient with standard postoperative nasal packing with Merocel and placing quilting sutures in septum leaving the nose unpacked in the postoperative period. We conducted the study in the tertiary care centre enrolling 82 patients in a quasi-randomised method of odd and even numbers placing them in the nasal packing group and the quilting group respectively....
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Abstract Our goal was to determine the most important predictors and construct a nomogram for overall survival (OS) in oral cavity squamous cell cancer (OCSCC) treated with primary surgery followed by observation, adjuvant radiation or chemoradiation. Multivariable analysis was performed using Cox Proportional Hazard model of 9258 OCSCC patients from Surveillance, Epidemiology and End Results Program (SEER) database treated with surgery from 2003 to 2009. Potential predictors of...
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Abstract The study was performed with 50 patients, 24 patients in Arm A and 26 patients in Arm B. Arm A—Conventional Telecobalt RT 66 Gy/33 fraction in stage T1N0M0 and stage T2N0M0 and Arm B—3D-CRT 66 Gy/33 fraction in T1N0M0 and T2N0M0 used. At the end of RT, 6 weeks, 3 months acute and late toxicities were noted by RTOG/EORTC morbidity scoring criteria for skin reaction, dysphagia and laryngeal toxicity. Fiber optic Laryngoscopy clinical assessment criteria were used to assess...
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Abstract To compare short and long-term graft uptake and hearing outcome of type I cartilage tympanoplasty between small, medium and large perforations using reinforced sliced conchal cartilage. A retrospective study conducted in a tertiary center. Fifty patients who under went type I tympanoplasty were enrolled. Their mean age was 29.30 years and follow-up time was 6 and 18 months. The preoperative, postoperative short-term and long-term hearing and graft uptake results were analyzed....
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Related ArticlesPotential role of autofluorescence imaging in determining biopsy of oral potentially malignant disorders: A large prospective diagnostic study. Oral Oncol. 2019 Aug 12;: Authors: Shi L, Li C, Shen X, Zhou Z, Liu W, Tang G Abstract Autofluorescence examination of oral tissues using the VELscope has been suggested as an adjunctive tool for cancer detection and diagnosis. This study aimed to determine the diagnostic value of VELscope in...
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Condition: Oral and Maxillofacial InjuriesIntervention: Other: surgical treatment of facial bone fractureSponsor: Tribhuvan University, NepalNot yet recruiting
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Conditions: Tongue Cancer; Floor of Mouth Squamous Cell CarcinomaIntervention: Diagnostic Test: UltrasoundSponsor: Region Örebro CountyRecruiting
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Condition: Neck PainInterventions: Other: Cervical manipulation intervention; Other: Placebo interventionSponsor: University of ValenciaRecruiting
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Condition: Head and Neck CancerInterventions: Drug: AMD3100; Drug: PembrolizumabSponsors: Massachusetts General Hospital; Merck Sharp & Dohme Corp.; AperiSys, IncNot yet recruiting
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Conditions: Glottis Tumor; Larynx CancerInterventions: Radiation: Single Vocal Cord Irradiation (SVCI); Procedure: Arm A: Transoral CO2-Laser Microsurgical Cordectomy (TLM)Sponsors: Olgun Elicin; University of Bern; The Netherlands Cancer Institute; University of Lausanne Hospitals; University Hospital, Geneva; University of ZurichNot yet recruiting
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Pain and Neck Dysfunction Following Dry Needling With and Without Intramuscular Electrical Stimulus.
Conditions: Neck Pain; Shoulder Pain; Myofascial PainInterventions: Procedure: Dry Needling (DN); Procedure: Dry needling with Intramuscular electrical stimulation (DNES)Sponsor: University of Mary Hardin-BaylorNot yet recruiting
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Condition: CancerInterventions: Behavioral: One-on-one teaching sessions; Behavioral: Telephone booster contactSponsor: Case Comprehensive Cancer CenterNot yet recruiting
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Condition: Atopic Dermatitis (AD)Intervention: Drug: KBL697Sponsors: KoBioLabs; Novotech (Australia) Pty LimitedNot yet recruiting
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Condition: Esophageal Squamous Cell CarcinomaIntervention: Drug: DurvalumabSponsor: Tiago BiachiNot yet recruiting
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Condition: Ovarian CancerIntervention: Other: DNA and RNA extraction from FFPE or frozen tissue sampleSponsor: Institut BergoniéNot yet recruiting
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