We appreciate Dr Aydin and colleagues' comments and questions, which allow us the opportunity to both clarify and strengthen our study.1
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Hi, I am Peter Gloviczki from Mayo Clinic, Editor-in-Chief of the Journal of Vascular Surgery: Venous and Lymphatic Disorders. We have several excellent articles in our September issue and I am pleased to introduce the four best papers that we selected for you.
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We aimed to compare mechanochemical ablation (MOCA) and thermal ablation (radiofrequency ablation and endovenous laser therapy) for venous ulcer healing in patients with clinical class 6 chronic venous insufficiency.
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Venous ablation (VA) is the recommended treatment of superficial venous insufficiency affecting the lower extremities. The safety and efficacy of the procedure in octogenarians have not been well studied. We postulate that VA in octogenarians is as safe and effective as in younger age groups.
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Drs Son, O'Donnell, and colleagues from Tufts Medical Center in Boston have given us a timely report on the crucial role of the “combined” condition of chronic venous and lymphatic insufficiency, defined as phlebolymphedema, and its impact on venous leg ulcers.1 Based on a unique, mutually interdependent venous-lymphatic system, which has an inseparable outflow system, its physiologic drainage functions are interdependent.
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The second edition of this text is a true treasury of information and is welcomed in the vascular surgical world. As noted in the forwards by both Drs Rockson and Villavicencio, there is an exuberance for the now “mainstream” acceptance of lymphedema into the brethren of arterial and venous disorders. In the first edition, the authors stated that the lymphatic system has been the subject of passive neglect for centuries and quote the late Michael Hume, former President of the American Venous Forum,...
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Endovenous ablation is the gold standard for treatment of chronic venous insufficiency secondary to axial venous incompetence. The two most common ablation modalities, laser (endovascular laser ablation [EVLA]) and radiofrequency ablation (RFA) have been shown to be efficacious. This study found that all endovenous interventions were effective in improving the clinical severity of varicose veins at 1 year despite differing rates of persistent vein occlusion.
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Pulmonary embolism (PE) remains a leading cause of death in pregnant women in the Western world. The use of a pregnancy-adapted algorithm in pregnant women with suspected PE was successful and safely avoided the ionizing radiation exposure from computed tomographic pulmonary angiography (CTA) in 32% to 65% of pregnant patients in their third to first trimesters, respectively.
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Cyanoacrylate glue is safe and effective for the treatment of chronic venous insufficiency.
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Red vine leaf extract (AS 195) may have an important role in mitigation of symptoms or prevention of chronic venous insufficiency.
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Proximal venous outflow obstruction (PVOO) in the iliac veins and superficial venous disease are inter-related in ways not fully understood. We observed among our patients undergoing vein stent placement for PVOO a significant number having had prior endovenous thermal ablations (EVTA) in their history. This study was undertaken to better characterize these patients and develop an algorithm in their management.
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We describe the case of a 46-year-old man with pulmonary thromboembolism caused by a popliteal venous aneurysm with thrombosis. The aneurysm was fusiform and partially saccular with a thrombus, and the caliber of the native popliteal vein was large. Tangential aneurysmectomy with lateral venorrhaphy was difficult because of the aneurysm type, and graft interposition was required because of the large venous diameter of the anastomosis site. The patient underwent aneurysm resection interposed with...
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Related ArticlesPain management in opioid maintenance treatment. Expert Opin Pharmacother. 2019 Aug 16;:1-13 Authors: Koller G, Schwarzer A, Halfter K, Soyka M Abstract Introduction: Opioid addiction is a worldwide disease with a significant impact. A multitude of physical and mental comorbidities are associated with opioid addiction, pain being one of the most relevant. Insufficient pain management may lead to a disruption in medical treatment, self-medication,...
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Our co-hosts discuss airway management and its important role in EMS, including common misconceptions and the standard all providers should strive for
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Please take a couple moments to answer these multiple-choice questions, which will help us capture how your agency is staying up to date on training for EMS treatment of bariatric patients
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Download this EMS1 airway management devices buying guide to learn key steps for product selection, purchasing and implementation
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Abstract Introduction We aim to assess the real-world, US patient-reported impact of ankylosing spondylitis (AS) on quality of life (QOL) across physical, discomfort, social, and emotional domains. Methods Demographic and QOL data were collected from a random sample of patients associated with the Spondylitis Association of America (SAA) from...
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Abstract Psoriatic arthritis (PsA) is a heterogeneous and inflammatory disease with diverse clinical manifestations, including psoriasis, nail psoriasis, peripheral joint disease, axial joint disease, enthesitis, and dactylitis. Typically, this varied clinical presentation complicates the clinician’s ability to distinguish PsA from other forms of arthritis. In the synovium of individuals with PsA, upregulation of the genes WNT3A, BMPR2, and TGFBR1 results in bone erosion and...
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Abstract Axial spondyloarthritis (axSpA) is a chronic and inflammatory rheumatic disease characterized by pain, structural and functional impairments, and reduced mobility and potential deformity of the axial skeleton. Treatment of axSpA includes pharmacological and non-pharmacological therapy. However, in the biologic era, unmet needs still remain for patients intolerant to or non-responders to biologic drugs and despite the development of new treatments, physical therapy and...
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Abstract Introduction Peficitinib is a novel orally bioavailable, once-daily Janus kinase (JAK) inhibitor approved in Japan for the treatment of rheumatoid arthritis (RA). This 2-year extension study of two global phase IIb trials investigated the long-term safety and effectiveness of peficitinib. Methods All eligible patients with moderate-to-severe RA including...
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The original version of this article unfortunately contains errors in Figure 4. An incorrect Figure 4D is published which is actually a repetition of Figure 2C (i.e., apoptosis rate in control vs. H2O2-treated group). The correct Figure 4D should be the aortic diameter of control vs. experimental groups. Also, the order of part figures (a\b\c\d) in Figure 4E is incorrect. The correct Figure 4 is given below.
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Related ArticlesEndoscopic repair of spontaneous skull base defects decreases the incidence rate of intracranial complications. Int Forum Allergy Rhinol. 2019 Aug 12;: Authors: Allensworth JJ, Rowan NR, Storck KA, Woodworth BA, Schlosser RJ Abstract BACKGROUND: Spontaneous skull base defects can result in life-threatening intracranial complications (ICCs), including meningitis and pneumocephalus. Endoscopic skull base reconstruction (ESBR) has traditionally...
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Related ArticlesLow bone mineral density of vertebral lateral projections can predict spinal radiographic damage in patients with ankylosing spondylitis. Clin Rheumatol. 2019 Aug 12;: Authors: Kim JW, Chung MK, Lee J, Kwok SK, Kim WU, Park SH, Ju JH Abstract OBJECTIVES: To investigate the association between bone mineral status and spinal radiographic damage in patients with ankylosing spondylitis (AS) and determine whether bone mineral status can predict...
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Related ArticlesComparing videolaryngoscope and direct laryngoscope use for nasotracheal intubation in patients with manual in-line stabilization. Can J Anaesth. 2019 Aug 13;: Authors: Shao LJ, Liu SH, Xue FS PMID: 31410646 [PubMed - as supplied by publisher]
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Related ArticlesIn reply: Comparing videolaryngoscope and direct laryngoscope use for nasotracheal intubation in patients with manual in-line stabilization. Can J Anaesth. 2019 Aug 13;: Authors: Roh GU, Kim JY PMID: 31410644 [PubMed - as supplied by publisher]
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Abstract Purpose In the past decade, an increasing number of otherwise healthy individuals suffered from invasive fungal infections due to inherited CARD9 mutations. Herein, we present a patient with a homozygous CARD9 mutation who was suffering from localized subcutaneous phaeohyphomycosis caused by the phytopathogenic fungus Pallidocercospora crystallina which has not been reported to cause infections in humans. ...
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Diabetes is a metabolic disease, partly due to hypoinsulinism, which affects ∼8% of the world’s adult population. Glibenclamide is known to promote insulin secretion by targeting β cells. Autophagy as a self-protective mechanism of cells has been widely studied and has particular physiological effects in different tissues or cells. However, the interaction between autophagy and glibenclamide is unclear. In this study, we investigated the role of autophagy in glibenclamide-induced insulin secretion...
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Objectives. The aim of this study was to investigate the effects of compound C on an in vivo mouse model of high-fat diet- (HFD-) induced obesity and hepatosteatosis. Methods. C57BL/6 mice were fed with a standard diet (n = 5) for 16 weeks and then injected saline once a day for 4 weeks as the normal chow group. Mice (n = 10) were fed with HFD for 16 weeks to induce obesity and hepatosteatosis and then divided into two groups: HFD + vehicle group injected with the vehicle solution (saline) and HFD + compound...
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Background. Thyroid dysfunction is the most common endocrine disorder in clinical practice, and about half of the population with thyroid dysfunction remains undiagnosed. There is a fairly wide spectrum of thyroid dysfunction, which can be identified by patterns of thyroid function test results. The prevalence of thyroid dysfunction among the population varies in different studies. Methods. A cross-sectional study was conducted from February 8th to April 8th, 2017, among patients who requested for...
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Related ArticlesIbrutinib outperforms FCR in CLL. Nat Rev Clin Oncol. 2019 Aug 15;: Authors: Romero D PMID: 31417194 [PubMed - as supplied by publisher]
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Abstract Research on learning through serious games has been gaining importance in recent years. We develop the serious game Tempoly, concerning the learning of the four arithmetic operations on polynomials. A quasi-experimental study was carried out with 95 students of 8th grade, to evaluate the reactions of the students to the game, the effects of the use of the game in the students’ learning, and the use of the game through time. According to data collected through a questionnaire,...
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Abstract The ever-increasing advances in technology have made it necessary to make use of new educational methods in educational systems. Therefore, in this study, the effects of robotics training on students’ creativity and learning physics were investigated. The research design was pretest posttest quasi-experimental, including one control and one treatment groups. The participants of the study included 120 males and females from 11th grade, studying at different schools in Tehran,...
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Abstract This study aimed to determine the effects of the traditional classroom model, distance education model and flipped classroom model designed according to ARCS (attention, relevance, confidence and satisfaction) motivation strategies on motivation and academic achievement levels. For this purpose, the study was conducted by using an experimental pretest-posttest control group design. Purposive sampling was used to determine the participants. Frequency, percentage, mean,...
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