Κυριακή 11 Αυγούστου 2019


A Review of PCSK9 Inhibitors and their effects on cardiovascular disease.
Related ArticlesA Review of PCSK9 Inhibitors and their effects on cardiovascular disease. Curr Top Med Chem. 2019 Aug 08;: Authors: Chen B, Zhao P, Shi X, Cui Y, Hou A Abstract BACKGROUND: Cardiovascular disease remains the leading cause of morbidity and mortality in the world, with elevated low density lipoprotein-cholesterol (LDL-C) levels as a major risk factor. Lower levels of LDL-C can effectively reduce the risk of cardiovascular disease. Proprotein...
Current topics in medicinal chemistry
20h
Pharmacology of ivabradine and the effect on chronic heart failure.
Related ArticlesPharmacology of ivabradine and the effect on chronic heart failure. Curr Top Med Chem. 2019 Aug 08;: Authors: Zhou Y, Wang J, Meng Z, Zhou S, Peng J, Chen S, Wang Q, Sun K Abstract Chronic heart failure (CHF) is a complex clinical syndrome with a high incidence worldwide. Although various types of pharmacological and device therapies are available for CHF, the prognosis is not ideal, for which, the control of increased heart rate (HR)...
Current topics in medicinal chemistry
20h
Bothrops alternatus snake venom induces cytokine expression and oxidative stress on renal function.
Related ArticlesBothrops alternatus snake venom induces cytokine expression and oxidative stress on renal function. Curr Top Med Chem. 2019 Aug 08;: Authors: Júnior FAN, Jorge ARC, Marinho AD, de Moraes Silveira JA, Alves NTQ, Costa PHS, Silva PLBE, Chaves-Filho AJM, Lima DB, Sampaio TL, de Morais GB, Evangelista JSAM, Martins AMC, Jr RSF, Macedo DS, Jorge RJB, Monteiro HSA Abstract BACKGROUND: Envenomation caused by Bothrops alternatus is common in...
Current topics in medicinal chemistry
20h
Homologation: A versatile molecular modification strategy to drug discovery.
Related ArticlesHomologation: A versatile molecular modification strategy to drug discovery. Curr Top Med Chem. 2019 Aug 08;: Authors: Lima LM, Alves MA, do Amaral DN Abstract Homologation is a concept introduced by Gerhard in 1853 to describe homologous series into organic chemistry. Since then the concept has been adapted and used in Medicinal Chemistry as one of the most important strategies for molecular modification. The homologation types, their...
Current topics in medicinal chemistry
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microRNAs in Cardiovascular Disease: Small Molecules but Big Roles.
Related ArticlesmicroRNAs in Cardiovascular Disease: Small Molecules but Big Roles. Curr Top Med Chem. 2019 Aug 08;: Authors: Yan B, Wang H, Tan Y, Fu W Abstract microRNAs (miRNAs) are an evolutionarily conserved class of small single-stranded noncoding RNAs. The aberrant expression of specific miRNAs has been implicated in the development and progression of diverse cardiovascular diseases. For many decades, miRNA therapeutics has flourished, taking...
Current topics in medicinal chemistry
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Fragment Based Approaches for Allosteric Metabotropic Glutamate Receptor (mGluR) Modulators.
Related ArticlesFragment Based Approaches for Allosteric Metabotropic Glutamate Receptor (mGluR) Modulators. Curr Top Med Chem. 2019 Aug 08;: Authors: Orgován Z, Ferenczy GG, Keserű GM Abstract Metabotropic glutamate receptors (mGluR) are members of the class C G-protein coupled receptors (GPCR-s) and have eight subtypes. These receptors are responsible for a variety of functions in the central and peripheral nervous systems and their modulation has...
Current topics in medicinal chemistry
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Late cholestatic syndrome due to previous perforating trauma: Case report.
Related ArticlesLate cholestatic syndrome due to previous perforating trauma: Case report. Int J Surg Case Rep. 2019 Aug 01;61:276-279 Authors: De Macedo FPPC, Maués CAD, Mendes Filho O, da Costa KG, Rodriguez JER, Csasznik I, Bergamasco JJC, da Silva Neto RA, da Silva Júnior RA Abstract INTRODUCTION: The presence of a foreign body obstructing the bile duct may appear through a typical picture of cholangitis, usually caused by the presence of gallstones....
pubmed: "int j surg case rep...
20h
Polymerase chain reaction of fistula drainage in sacrococcygeal tuberculosis.
Related ArticlesPolymerase chain reaction of fistula drainage in sacrococcygeal tuberculosis. Int J Surg Case Rep. 2019 Jul 30;61:275 Authors: Foye PM, Bains M, Tangri V PMID: 31400732 [PubMed - as supplied by publisher]
pubmed: "int j surg case rep...
20h
Peritoneal metastases from malignant degeneration of ectopic gastric epithelium in Meckel's diverticulum: A case report.
Related ArticlesPeritoneal metastases from malignant degeneration of ectopic gastric epithelium in Meckel's diverticulum: A case report. Int J Surg Case Rep. 2019 Jul 12;: Authors: El Bahesh E, Abell BM, Sugarbaker PH, Finianos A, Baird-Howell M, Ahlgren JD Abstract BACKGROUND: Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract, resulting from incomplete obliteration of the omphalomesenteric duct in early fetal...
pubmed: "int j surg case rep...
20h
Cystic mesenteric lymphangioma: A case report.
Related ArticlesCystic mesenteric lymphangioma: A case report. Int J Surg Case Rep. 2019 Jul 25;: Authors: Thiam O, Faye PM, Niasse A, Seye Y, Gueye ML, Sarr IS, Toure AO, Seck M, Cisse M, Dieng M Abstract INTRODUCTION: Cystic lymphangioma is a benign malformative tumor. The abdominal localization is rare. The diagnosis is not easy in preoperative period. The surgery is the choice in the abdominal and symptomatic localization. PRESENTATION OF...
pubmed: "int j surg case rep...
20h
Twenty-year survival of gastric cancer with peritoneal metastases using long-term normothermic intraperitoneal 5-fluorouracil and systemic mitomycin C: A case report.
Related ArticlesTwenty-year survival of gastric cancer with peritoneal metastases using long-term normothermic intraperitoneal 5-fluorouracil and systemic mitomycin C: A case report. Int J Surg Case Rep. 2019 Jul 12;: Authors: Sugarbaker PH Abstract BACKGROUND: Primary gastric cancer that presents with peritoneal metastases has few options for successful treatment. METHODS: A simplified treatment plan started with total gastrectomy and hyperthermic...
pubmed: "int j surg case rep...
20h
Peritoneal tunnels: A site at risk for treatment failure when performing treatments for peritoneal metastases. A case series of 2 patients.
Related ArticlesPeritoneal tunnels: A site at risk for treatment failure when performing treatments for peritoneal metastases. A case series of 2 patients. Int J Surg Case Rep. 2019 Jul 19;: Authors: Sugarbaker PH Abstract BACKGROUND: Peritoneal metastases from gastrointestinal cancer can be treated by a combination of surgery to remove visible evidence of disease and perioperative intraperitoneal chemotherapy to eradicate microscopic disease. Complete...
pubmed: "int j surg case rep...
20h
Mesocolic hernia following retroperitoneal laparoscopic radical nephrectomy: A case report.
Related ArticlesMesocolic hernia following retroperitoneal laparoscopic radical nephrectomy: A case report. Int J Surg Case Rep. 2019 Jul 31;: Authors: Yoshida N, Fujita F, Ueda K, Ogata S, Shigaki T, Yomoda T, Ohchi T, Mizobe T, Kinugasa T, Akagi Y Abstract INTRODUCTION: Small bowel obstruction (SBO) caused by an internal hernia through a mesocolon after retroperitoneal laparoscopic nephrectomy (RLN) is rare. PRESENTATION OF CASE: A 66-year-old...
pubmed: "int j surg case rep...
20h
Bilateral catamenial hemopneumothorax: Diagnostic & management challenges.
Related ArticlesBilateral catamenial hemopneumothorax: Diagnostic & management challenges. Int J Surg Case Rep. 2019 Jul 31;61:271-274 Authors: AlAqeel S, AlJehani Y, AlMuhaish M Abstract INTRODUCTION: Catamenial pneumothorax (CP) is a rare and usually miss diagnosed condition that is often characterized by non- specific respiratory or gynecological symptoms. A high index of suspicion is warranted for early diagnosis and management. PRESENTATION...
pubmed: "int j surg case rep...
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Image-guided endoscopic marsupialization technique for frontal sinus mucocele with orbital extension: A case report.
Related ArticlesImage-guided endoscopic marsupialization technique for frontal sinus mucocele with orbital extension: A case report. Int J Surg Case Rep. 2019 Jul 31;61:259-262 Authors: Casale M, Costantino A, Sabatino L, Cassano M, Moffa A, Rinaldi V Abstract INTRODUCTION: Frontal sinus mucocele with intra-orbital extension represents a rare benign cyst-like lesion. Surgical management could be summarized in an open approach, an endoscopic marsupialization...
pubmed: "int j surg case rep...
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Instability treatment due to upper cervical tuberculous spondylitis.
Related ArticlesInstability treatment due to upper cervical tuberculous spondylitis. Int J Surg Case Rep. 2019 Jul 23;61:267-270 Authors: Lumban Tobing SDA, Irawan R, Triadi Wijaya M, Antoro A, Setiawan E, Septian R Abstract INTRODUCTION: Upper Cervical Spondylitis is a rare case, approximately 0.3-1% of all Tuberculous Spondylitis. Nevertheless, it causes destruction and morbidity more than Tuberculous Spondylitis at other side. Instability at upper...
pubmed: "int j surg case rep...
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Case report of severe psychiatric sequelae in a 16-year-old female following resection of a purely dopamine-secreting ganglioneuroma.
Related ArticlesCase report of severe psychiatric sequelae in a 16-year-old female following resection of a purely dopamine-secreting ganglioneuroma. Int J Surg Case Rep. 2019 Jul 19;61:263-266 Authors: Chai L, Ciullo S, Prasad R Abstract BACKGROUND: Ganglioneuromas (GN) are rare, benign tumors derived from neural crest cells. They are in the same family of neuroblastic tumors that includes the intermediate ganglioneuroblastoma (GNB) and the malignant...
pubmed: "int j surg case rep...
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Good functional outcome evaluation of free vascularized fibular head graft (FVFHG) as treatment after resection of giant cell tumor (GCT) campanacci 3 at proximal humerus: A case report.
Related ArticlesGood functional outcome evaluation of free vascularized fibular head graft (FVFHG) as treatment after resection of giant cell tumor (GCT) campanacci 3 at proximal humerus: A case report. Int J Surg Case Rep. 2019 Aug 01;61:254-258 Authors: Saleh R, Yurianto H, Pasallo P, Guatama A, Subagio ES Abstract INTRODUCTION: Giant cell tumor (GCT) is benign aggressive tumors with a high rate of recurrence and capacity to metastasize. Wide resection...
pubmed: "int j surg case rep...
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Incidentally discovered huge retroperitoneal mucinous cystadenoma with successful laparoscopic management: Case report.
Related ArticlesIncidentally discovered huge retroperitoneal mucinous cystadenoma with successful laparoscopic management: Case report. Int J Surg Case Rep. 2019 Jul 19;61:242-245 Authors: Foula MS, AlQattan AS, AlQurashi AM, AlShaqaq HM, Mirza Gari MK Abstract INTRODUCTION: Retroperitoneal cystic lesions are uncommon heterogeneous clinical entities with no definite incidence. Their clinical presentations are different and their diagnosis is challenging....
pubmed: "int j surg case rep...
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Response to article: "Unusual anatomical variation: tetrafurcation of the coeliac trunk".
Related ArticlesResponse to article: "Unusual anatomical variation: tetrafurcation of the coeliac trunk". Surg Radiol Anat. 2019 Aug 09;: Authors: Whitley A, Kachlik D PMID: 31399767 [PubMed - as supplied by publisher]
radiol anat
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Cell-intrinsic survival signals. The role of autophagy in metastatic dissemination and tumor cell dormancy.
Related ArticlesCell-intrinsic survival signals. The role of autophagy in metastatic dissemination and tumor cell dormancy. Semin Cancer Biol. 2019 Aug 07;: Authors: Vera-Ramirez L Abstract Metastasis is the main cause of cancer-related deaths. Disseminated tumor cells (DTCs), which seed metastasis, can remain undetected in a dormant state for decades after treatment of the primary tumor and their persistence is the main cause of late relapse and death...
pubmed: future oncology
20h
Genetic and epigenetic analyses of aldosterone-producing adenoma with hypercortisolemia.
Related ArticlesGenetic and epigenetic analyses of aldosterone-producing adenoma with hypercortisolemia. Steroids. 2019 Aug 07;:108470 Authors: Kometani M, Yoneda T, Demura M, Aono D, Gondoh Y, Karashima S, Nishimoto K, Yasuda M, Horike SI, Takeda Y Abstract DNA methylation is associated with excess cortisol and aldosterone. The DNA encoding aldosterone synthase (CYP11B2) and 11β-hydroxylase (CYP11B1), which catalyzes the final step of cortisol biosynthesis,...
pubmed: future oncology
20h
The New Immunotherapy Combinations in the Treatment of Advanced Non-Small Cell Lung Cancer: Reality and Perspectives.
Related ArticlesThe New Immunotherapy Combinations in the Treatment of Advanced Non-Small Cell Lung Cancer: Reality and Perspectives. Curr Clin Pharmacol. 2019 Aug 09;: Authors: Rocco D, Gravara LD, Gridelli C Abstract BACKGROUND: In the recent years, immunotherapeutics and specifically immune-checkpoints inhibitors have marked a significant shift in the diagnostic and therapeutic algorithm of non small cell lung cancer (NSCLC), allowing us to use immunotherapy...
pubmed: future oncology
20h
Artificial intelligence in digital pathology - new tools for diagnosis and precision oncology.
Related ArticlesArtificial intelligence in digital pathology - new tools for diagnosis and precision oncology. Nat Rev Clin Oncol. 2019 Aug 09;: Authors: Bera K, Schalper KA, Rimm DL, Velcheti V, Madabhushi A Abstract In the past decade, advances in precision oncology have resulted in an increased demand for predictive assays that enable the selection and stratification of patients for treatment. The enormous divergence of signalling and transcriptional...
pubmed: future oncology
20h
Targeting sickle cell disease root-cause pathophysiology with small molecules.
Related ArticlesTargeting sickle cell disease root-cause pathophysiology with small molecules. Haematologica. 2019 Aug 08;: Authors: Saunthararajah Y Abstract The complex, frequently devastating, multi-organ pathophysiology of sickle cell disease has a single root-cause of polymerization of deoxygenated sickle hemoglobin. A logical approach to disease modification therefore is to interdict this root-cause. Ideally, such interdiction would utilize small...
pubmed: future oncology
20h
EMT and Stemness-Key Players in Pancreatic Cancer Stem Cells.
Related ArticlesEMT and Stemness-Key Players in Pancreatic Cancer Stem Cells. Cancers (Basel). 2019 Aug 08;11(8): Authors: Rodriguez-Aznar E, Wiesmüller L, Sainz B, Hermann PC Abstract Metastasis and tumor progression are the major cause of death in patients suffering from pancreatic ductal adenocarcinoma. Tumor growth and especially dissemination are typically associated with activation of an epithelial-to-mesenchymal transition (EMT) program. This...
pubmed: future oncology
20h
Future Oncology; +39 new citations
39 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2019/08/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: future oncology
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Future Oncology; +39 new citations
39 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2019/08/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: future oncology
1d
Future Oncology; +28 new citations
28 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2019/08/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: future oncology
2d
Future Oncology; +28 new citations
28 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2019/08/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: future oncology
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A rare case of familial middle mediastinal paraganglioma.
Related ArticlesA rare case of familial middle mediastinal paraganglioma. Asian Cardiovasc Thorac Ann. 2019 Aug 09;:218492319870609 Authors: Tirunagari V, Santosham R, Santosham R, Devanayagam S PMID: 31398996 [PubMed - as supplied by publisher]
Rare Cancers
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Clinicopathological features and survival for gallbladder NEN: A population-based study.
Related ArticlesClinicopathological features and survival for gallbladder NEN: A population-based study. Endocr Connect. 2019 Aug 01;: Authors: Cen D, Liu H, Wan Z, Lin Z, Wang Y, Xu J, Liang Y Abstract PURPOSE: Gallbladder neuroendocrine neoplasm (GB-NEN) is a relatively rare neoplasm, accounting for 0.5% of all neuroendocrine neoplasm cases and 2.1% of gallbladder cancers. Because of the limited understanding of GB-NEN, the aim of this study was to...
Rare Cancers
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Cytopathology approach to rare salivary gland lesions with oncocytic features.
Related ArticlesCytopathology approach to rare salivary gland lesions with oncocytic features. Diagn Cytopathol. 2019 Aug 08;: Authors: El Hussein S, Khader SN Abstract Salivary glands located in the head and neck area are known to have different lesions with prominent oncocytic features. Fine needle aspiration is usually the initial approach in the management of these lesions, whether they represent neoplastic or non-neoplastic processes. Owing to the...
Rare Cancers
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Tumour growth activation by the central nervous system--An integrative theory of cancer.
Related ArticlesTumour growth activation by the central nervous system--An integrative theory of cancer. Stress Health. 2019 Aug 08;: Authors: Recio A Abstract The currently recognised mechanisms of the biology of cancer are not yet enough to explain the high incidence of the disease in industrialised countries. Survival and proliferation of cancer cells demand a well orchestrated combination of functional capabilities, or hallmarks, which requires complex...
Rare Cancers
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Genetic Changes of P53 and Kras in Gallbladder Carcinoma in Kumaon Region of Uttarakhand.
Related ArticlesGenetic Changes of P53 and Kras in Gallbladder Carcinoma in Kumaon Region of Uttarakhand. J Gastrointest Cancer. 2019 Aug 09;: Authors: Shukla SK, Singh G, Shahi KS, Bhuvan, Pant P Abstract BACKGROUND: Gallbladder carcinoma is a highly lethal but relatively rare neoplasm of the digestive tract. p53 mutations are one of the most frequent genetic alterations in human cancers and are thought to play a role in pathogenesis of several malignancies....
Rare Cancers
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Genomic characterization in triple-negative primary myelofibrosis and other myeloid neoplasms with bone marrow fibrosis.
Related ArticlesGenomic characterization in triple-negative primary myelofibrosis and other myeloid neoplasms with bone marrow fibrosis. Ann Hematol. 2019 Aug 08;: Authors: Alvarez-Larrán A, López-Guerra M, Rozman M, Correa JG, Hernández-Boluda JC, Tormo M, Martínez D, Martín I, Colomer D, Esteve J, Cervantes F Abstract Triple-negative primary myelofibrosis (TN-PMF) and other myeloid neoplasms with associated bone marrow fibrosis such as the myelodysplastic...
Rare Cancers
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Breast metastasis from primary lung adenocarcinoma in a young woman: A case report and literature review.
Related ArticlesBreast metastasis from primary lung adenocarcinoma in a young woman: A case report and literature review. World J Clin Oncol. 2019 Jul 24;10(7):269-278 Authors: Enrico D, Saucedo S, Bravo I Abstract BACKGROUND: Breast metastasis from extra mammary malignancies is rare. An incidence of 0.2%-1.3% has been reported in the literature, including that from different types of malignant neoplasms. CASE SUMMARY: We present a case of a...
Rare Cancers
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Primary Papillary Thyroid Cancer of a Thyroglossal Duct Cyst.
Related ArticlesPrimary Papillary Thyroid Cancer of a Thyroglossal Duct Cyst. Ear Nose Throat J. 2019 Mar;98(3):136-138 Authors: Liaw J, Cochran E, Wilson MN Abstract Papillary thyroid carcinoma in a thyroglossal duct cyst is very rare. We present the case of a teenage boy with a large thyroglossal duct cyst containing papillary thyroid carcinoma. There was no evidence of carcinoma within the thyroid gland, making this an important case of primary thyroglossal...
Rare Cancers
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Giant Cell Tumor of the Carotid Body: A Rare Tumor in a Novel Location.
Related ArticlesGiant Cell Tumor of the Carotid Body: A Rare Tumor in a Novel Location. Ear Nose Throat J. 2019 Mar;98(3):165-168 Authors: Chowdhary P, Makar GS, Holdbrook T, Spalla TC Abstract Primary giant cell tumor of soft tissue (GCT-ST) is a rare entity that is considered the soft tissue equivalent of giant cell tumor of bone. It most commonly arises in soft tissues of the trunk and extremities, with occurrence in the head and neck being extremely...
Rare Cancers
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Colorectal Lymphoma: A Contemporary Case Series.
Related ArticlesColorectal Lymphoma: A Contemporary Case Series. Dis Colon Rectum. 2019 06;62(6):694-702 Authors: Skube SJ, Arsoniadis EG, Sulciner ML, Gilles SR, Gaertner WB, Madoff RD, Melton GB, Peterson BA, Kwaan MR Abstract BACKGROUND: Colon and rectal lymphomas are rare and can occur in the context of posttransplant lymphoproliferative disorder. Evidence-based management guidelines are lacking. OBJECTIVE: The purpose of this study was...
Rare Cancers
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Recent advances in the regulation of testicular germ cell tumors by microRNAs.
Related ArticlesRecent advances in the regulation of testicular germ cell tumors by microRNAs. Front Biosci (Landmark Ed). 2019 03 01;24:765-776 Authors: Batool A, Liu XM, Zhang CL, Hao CF, Chen SR, Liu YX Abstract Testicular germ cell tumors (TGCTs) are generally rare but represent the most common solid tumors in young men. They are classified broadly into seminoma, which resemble primordial germ cells (PGCs), and non-seminoma, which are either undifferentiated...
Rare Cancers
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Superior Mesenteric Artery Pseudoaneurysms in Patients With Familial Adenomatous Polyposis-Associated Intra-abdominal Desmoids: Case Series.
Related ArticlesSuperior Mesenteric Artery Pseudoaneurysms in Patients With Familial Adenomatous Polyposis-Associated Intra-abdominal Desmoids: Case Series. Dis Colon Rectum. 2019 06;62(6):721-726 Authors: Bolshinsky V, Xhaja X, Halleran DR, Church J Abstract BACKGROUND: Rupture of a superior mesenteric artery pseudoaneurysm is a rare but potentially lethal complication in patients with familial adenomatous polyposis and desmoid disease. OBJECTIVE:...
Rare Cancers
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Isolated recurrent myelitis in a persistent MOG positive patient.
Related ArticlesIsolated recurrent myelitis in a persistent MOG positive patient. Mult Scler Relat Disord. 2019 May;30:163-164 Authors: Anis S, Regev K, Pittock SJ, Flanagan EP, Alcalay Y, Gadoth A Abstract MOG-Ab positive CNS demyelination typically involves the optic nerve and spinal cord. Recurrent episodes of myelitis without optic neuritis are very rare and according to current literature review represent about 3-5% of positive MOG-Ab cases. We...
Rare Cancers
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Extramedullary Haematopoiesis in Axillary Lymph Nodes of Breast Carcinoma Patients Receiving Neoadjuvant Chemotherapy: A Potential Diagnostic Pitfall.
Related ArticlesExtramedullary Haematopoiesis in Axillary Lymph Nodes of Breast Carcinoma Patients Receiving Neoadjuvant Chemotherapy: A Potential Diagnostic Pitfall. Pathobiology. 2019;86(2-3):167-172 Authors: Badr NM, Roberts C, Shaaban AM Abstract Extramedullary haematopoiesis (EMH) in the axillary lymph node of breast cancer patients is extremely rare but when encountered can represent a diagnostic challenge. We aim to highlight this incidental...
Rare Cancers
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Breast Tumours Resembling the Tall Cell Variant of Thyroid Papillary Carcinoma: Are They Part of the Papillary Carcinoma Spectrum or a Distinct Entity?
Related ArticlesBreast Tumours Resembling the Tall Cell Variant of Thyroid Papillary Carcinoma: Are They Part of the Papillary Carcinoma Spectrum or a Distinct Entity? Pathobiology. 2019;86(2-3):83-91 Authors: Toss MS, Billingham K, Egbuniwe IU, Moreno F, Abass A, Rakha EA Abstract BACKGROUND: Papillary tumours of the breast are diagnostically challenging lesions and represent a wide spectrum of diseases from papilloma to invasive papillary carcinoma....
Rare Cancers
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A lung squamous carcinoma patient with ROS1 rearrangement sensitive to crizotinib.
Related ArticlesA lung squamous carcinoma patient with ROS1 rearrangement sensitive to crizotinib. Cancer Chemother Pharmacol. 2018 09;82(3):561-564 Authors: Ju L, Han M, Su J, Wu C, Dong Z Abstract It is widely known that ROS1 rearrangement mostly occurs in the adenocarcinoma subtype of non-small-cell lung cancer. Patients with squamous cell carcinoma harboring ROS1 rearrangement are extremely rare. This is a case report of a squamous cell carcinoma...
Rare Cancers
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Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis.
Related ArticlesGenome sequencing uncovers phenocopies in primary progressive multiple sclerosis. Ann Neurol. 2018 07;84(1):51-63 Authors: Jia X, Madireddy L, Caillier S, Santaniello A, Esposito F, Comi G, Stuve O, Zhou Y, Taylor B, Kilpatrick T, Martinelli-Boneschi F, Cree BAC, Oksenberg JR, Hauser SL, Baranzini SE Abstract OBJECTIVE: Primary progressive multiple sclerosis (PPMS) causes accumulation of neurological disability from disease onset without...
Rare Cancers
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Ganglioglioma in children and young adults: single institution experience and review of the literature.
Related ArticlesGanglioglioma in children and young adults: single institution experience and review of the literature. J Neurooncol. 2018 Sep;139(3):739-747 Authors: Zaky W, Patil SS, Park M, Liu D, Wang WL, Wani KM, Calle S, Ketonen L, Khatua S Abstract BACKGROUND: Ganglioglioma (GG) is a rare mixed glial-neuronal neoplasm accounting for 0.5-5% of all pediatric central nervous system (CNS) tumors. Rarity of this tumor has precluded defining robust...
Rare Cancers
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A narrative review and update on management following negative prostate biopsy.
Related ArticlesA narrative review and update on management following negative prostate biopsy. Curr Opin Urol. 2018 07;28(4):398-402 Authors: Cheung DC, Li J, Finelli A Abstract PURPOSE OF REVIEW: Prostate cancer has traditionally been diagnosed using systematic transrectal ultrasound-guided biopsy. However, given the inherent nature of sampling, a negative biopsy does not exclude clinically significant prostate cancer (csPCa), and continued controversy...
Rare Cancers
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Treatment Outcomes in Male Breast Cancer: A Retrospective Analysis of 161 Patients.
Related ArticlesTreatment Outcomes in Male Breast Cancer: A Retrospective Analysis of 161 Patients. Clin Oncol (R Coll Radiol). 2018 06;30(6):354-365 Authors: Wan BA, Ganesh V, Zhang L, Sousa P, Drost L, Lorentz J, Vesprini D, Lee J, Rakovitch E, Lu FI, Eisen A, Yee C, Lam H, Chow E Abstract AIMS: Male breast cancer is a rare disease with limited evidence-based guidelines for treatment. This study aimed to identify demographic, pathological and clinical...
Rare Cancers
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[Presacral lesion at the rima ani].
Related Articles[Presacral lesion at the rima ani]. Pathologe. 2018 Mar;39(2):181-185 Authors: Seeling C, Hirte C, Scheuerle A, Möller P, Barth TFE Abstract A 26-year-old woman presented with a painful bulge at the rima ani. The tumor was located in the presacral region. Histological examination revealed a well-circumscribed biphenotypical tumor with papillary configured myxoid areas and strongly sclerosing regions. This case of a myxopapillary ependymoma...
Rare Cancers
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Rare case of obstructive duodenal phytobezoar caused by two lipomas.
Related ArticlesRare case of obstructive duodenal phytobezoar caused by two lipomas. J Dig Dis. 2018 Jan;19(1):48-51 Authors: Cho E, Jun CH, Park EK, Park CH, Kim HS, Choi SK, Rew JS PMID: 28715114 [PubMed - indexed for MEDLINE]
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Pulmonary sarcomatoid carcinoma presenting both ALK rearrangement and PD-L1 high positivity: A case report on the therapeutic regimen.
Related ArticlesPulmonary sarcomatoid carcinoma presenting both ALK rearrangement and PD-L1 high positivity: A case report on the therapeutic regimen. Medicine (Baltimore). 2019 Aug;98(32):e16754 Authors: D'Antonio F, De Sanctis R, Bolengo I, Destro A, Rahal D, De Vincenzo F, Santoro A Abstract RATIONALE: Pulmonary sarcomatoid carcinoma (PSC) represents <1% of all lung cancers and is characterized by a very poor prognosis. The optimal therapeutic...
Rare Cancers
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Rationale for evaluating breast cancers of Lynch syndrome patients for mismatch repair gene expression.
Related ArticlesRationale for evaluating breast cancers of Lynch syndrome patients for mismatch repair gene expression. Breast Cancer Res Treat. 2019 Aug 07;: Authors: Sorscher S Abstract BACKGROUND: Lynch Syndrome (LS) patients harbor germline mutations in one of several mismatch repair (MMR) genes and are predisposed to the development of colon and endometrial cancers and multiple other cancers types as well. Tumors related to LS are characterized...
Rare Cancers
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Report of three cases of gastric choriocarcinomas-an emphasis on morphologic changes in the non-affected gastric mucosa.
Related ArticlesReport of three cases of gastric choriocarcinomas-an emphasis on morphologic changes in the non-affected gastric mucosa. J Gastrointest Oncol. 2019 Aug;10(4):810-814 Authors: Guzmán-López JC, Lino-Silva LS, Salcedo-Hernández RA, Zepeda-Najar C Abstract Primary gastric choriocarcinomas (PGC) are very rare and aggressive neoplasms with a worrisome prognosis. Most cases are reported in Asia and presented in middle-aged adults with male predominance....
Rare Cancers
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Molecular profiling of biliary cancers reveals distinct molecular alterations and potential therapeutic targets.
Related ArticlesMolecular profiling of biliary cancers reveals distinct molecular alterations and potential therapeutic targets. J Gastrointest Oncol. 2019 Aug;10(4):652-662 Authors: Weinberg BA, Xiu J, Lindberg MR, Shields AF, Hwang JJ, Poorman K, Salem ME, Pishvaian MJ, Holcombe RF, Marshall JL, Morse MA Abstract Background: Biliary tract cancers (BTCs) are a heterogeneous group of aggressive, rare malignancies with limited standard chemotherapeutic...
Rare Cancers
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[Ectopic pulmonary calcification after parathyroidectomy in multiple myeloma].
Related Articles[Ectopic pulmonary calcification after parathyroidectomy in multiple myeloma]. Rinsho Ketsueki. 2019;60(7):785-790 Authors: Ando K, Imaizumi Y, Yamamoto K, Tanaka M, Zaizen Y, Taguchi M, Sakaki C, Ichinose M, Furumoto T, Hashimoto M, Fujioka M, Sakamoto H, Hourai M, Itonaga H, Sato S, Sawayama Y, Hata T, Mukae H, Fukuoka J, Inoue D, Miyazaki Y Abstract Ectopic soft tissue calcification (ESTC), a rare clinical condition, causes tissue...
Rare Cancers
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Small Cell and Squamous Cell Carcinomas of the Head and Neck: Comparing Incidence and Survival Trends Based on Surveillance, Epidemiology, and End Results (SEER) Data.
Related ArticlesSmall Cell and Squamous Cell Carcinomas of the Head and Neck: Comparing Incidence and Survival Trends Based on Surveillance, Epidemiology, and End Results (SEER) Data. Oncologist. 2019 Aug 07;: Authors: Bean MB, Liu Y, Jiang R, Steuer CE, Patel M, McDonald MW, Higgins KA, Beitler JJ, Shin DM, Saba NF Abstract BACKGROUND: Small cell carcinomas of the head and neck (SmCCHNs) are rare neoplasms with an unfavorable prognosis. Population-based...
Rare Cancers
2d
Endocervical adenocarcinoma in situ (AIS) with ovarian and pulmonary involvement: report of a case and review of the literature suggesting a "seed and soil hypothesis".
Related ArticlesEndocervical adenocarcinoma in situ (AIS) with ovarian and pulmonary involvement: report of a case and review of the literature suggesting a "seed and soil hypothesis". J Cancer Res Clin Oncol. 2019 Aug;145(8):2061-2069 Authors: Horn LC, Höhn AK, Stark S, Einenkel J, Borte G, Haak A, Siebolts U, Brambs CE Abstract PURPOSE: Cervical cancer metastases to the ovary may occur with advanced tumor stage, deep cervical stromal involvement and...
Rare Cancers
2d

Genetic profiling as a clinical tool in advanced parathyroid carcinoma.
Related ArticlesGenetic profiling as a clinical tool in advanced parathyroid carcinoma. J Cancer Res Clin Oncol. 2019 Aug;145(8):1977-1986 Authors: Kutahyalioglu M, Nguyen HT, Kwatampora L, Clarke C, Silva A, Ibrahim E, Waguespack SG, Cabanillas ME, Jimenez C, Hu MI, Sherman SI, Kopetz S, Broaddus R, Dadu R, Wanland K, Williams M, Zafereo M, Perrier N, Busaidy NL Abstract CONTEXT: Parathyroid carcinoma (PC) is a rare endocrine malignancy with no approved...
Rare Cancers
2d
Myelitis: A Rare Presentation of Epstein Barr Virus.
Related ArticlesMyelitis: A Rare Presentation of Epstein Barr Virus. J Assoc Physicians India. 2019 Mar;67(3):93-95 Authors: Singh JR, Ibraheem K, Jain D, Yogendra K Abstract EBV associated nervous system complications includes encephalitis, meningitis, cerebellitis, polyradiculomyelitis, transverse myelitis, cranial and peripheral neuropathies, and psychiatric abnormalities are usually more commonly seen in immunocompromised patients and rarely in immunocompetent...
Rare Cancers
2d
[Organ-sparing partial orchietectomy for testicular adenomatoid tumor].
Related Articles[Organ-sparing partial orchietectomy for testicular adenomatoid tumor]. Beijing Da Xue Xue Bao Yi Xue Ban. 2019 Apr 18;51(2):365-368 Authors: Ye JF, Wang B, Ma LL, Zhao L, Wang GL, Hong K Abstract OBJECTIVE: The incidence of testicular tumors is relatively low which are mainly malignant, so the main way to treat testicular tumors is radical testicular resection. Testicular adenomatoid tumor is a rare testicular benign tumor, but is easily...
Rare Cancers
2d
808 nm laser-triggered NIR-II emissive rare-earth nanoprobes for small tumor detection and blood vessel imaging.
Related Articles808 nm laser-triggered NIR-II emissive rare-earth nanoprobes for small tumor detection and blood vessel imaging. Mater Sci Eng C Mater Biol Appl. 2019 Jul;100:260-268 Authors: Li X, Jiang M, Li Y, Xue Z, Zeng S, Liu H Abstract Optical bioimaging in second near-infrared window (NIR-II, 1000-1700 nm) has been emerged as an indispensable tool for highly sensitive disease detection. In this work, intense NIR-II emissive polyacrylic acid...
Rare Cancers
2d
HMGB1 as a Potential Biomarker and Therapeutic Target for Malignant Mesothelioma.
Related ArticlesHMGB1 as a Potential Biomarker and Therapeutic Target for Malignant Mesothelioma. Dis Markers. 2019;2019:4183157 Authors: Wang Y, Jiang Z, Yan J, Ying S Abstract Malignant mesothelioma (MM) is a rare, aggressive, and highly lethal cancer that is substantially induced by exposure to asbestos fibers. High-mobility group box 1 (HMGB1) is an intriguing proinflammatory molecule involved in MM. In this review, we describe the possible crucial...
Rare Cancers
2d
Lymphnode metastasis of thyroid cancer misinterpreted as lateral aberrant thyroid 40 years before identification of primary tumor. Case report and review of the literature.
Related ArticlesLymphnode metastasis of thyroid cancer misinterpreted as lateral aberrant thyroid 40 years before identification of primary tumor. Case report and review of the literature. Pathologica. 2018 Dec;110(4):313-315 Authors: Riva G, Villanova M, Francia G, Valotto G, Mezzetto L, Toaiari M, Eccher A, Novelli L Abstract The differential diagnosis between lateral ectopic thyroid tissue with orthotopic normal gland and metastatic thyroid carcinoma...
Rare Cancers
2d
Calcifying aponeurotic fibroma: a core biopsy-based diagnosis.
Related ArticlesCalcifying aponeurotic fibroma: a core biopsy-based diagnosis. Pathologica. 2018 Dec;110(4):307-312 Authors: Motta F, Scavo S, Vecchio GM, Fuccio-Sanzà G, Nicolosi F, Magro G Abstract Calcifying aponeurotic fibroma (CAF) is a very rare tumor of the extremities, which can be difficult to diagnose due to its wide cyto-architectural pattern. We herein report the clinicopathologic features of a case of CAF localized on the dorsal face of...
Rare Cancers
2d
Unclassified sex cord/gonadal stromal testis tumor with a "pure" spindle cell component: a case report.
Related ArticlesUnclassified sex cord/gonadal stromal testis tumor with a "pure" spindle cell component: a case report. Pathologica. 2018 Dec;110(4):302-306 Authors: Spairani C, Squillaci S, Pitino A, Montefiore F, Fusco W Abstract Unclassified sex cord/gonadal stromal tumors (SCSTs) composed predominantly of spindle cells are rare. Very few cases have been documented to date. Here, we report a case of "pure" spindle cell tumor of the left testis in...
Rare Cancers
2d
Breast Cancer with Paraneoplastic Syndrome in a 72 Year Old Male Patient.
Related ArticlesBreast Cancer with Paraneoplastic Syndrome in a 72 Year Old Male Patient. Mymensingh Med J. 2019 Jan;28(1):254-258 Authors: Yesmin S, Sanyal M, Hasan MJ Abstract Breast cancer in male is rare which accounts about 1% of all malignant breast neoplasm cases. Since paraneoplastic syndrome is unusual with male breast cancer, very few reported cases are found. A72- year-old gentleman presented with proximal myopathy in all four limbs was referred...
Rare Cancers
2d
Transmigrated and Impacted Upper 2nd Premolar Associated with Dentigerous Cyst.
Related ArticlesTransmigrated and Impacted Upper 2nd Premolar Associated with Dentigerous Cyst. Mymensingh Med J. 2019 Jan;28(1):237-240 Authors: Rahman A, Tauhid F, Begum S, Saifuddin M, Hossain MA, Paul P, Abdullah AA Abstract A male patient about 45 years old came to my private clinic "The Dental Aid", Dhanmondi, Dhaka, Bangladesh last year (February 2016) with the complaint of pain at right palatal premolar region. On clinical examination we found...
Rare Cancers
2d
Advanced chondrosarcoma of the pelvis: A rare case of urinary obstruction.
Related ArticlesAdvanced chondrosarcoma of the pelvis: A rare case of urinary obstruction. Arch Ital Urol Androl. 2019 Jan 17;90(4):293-294 Authors: Olivieri V, Fortunati V, Annoscia S, Massarelli M, Bellei L, Ollino M, Manzi E, Maurizi A, De Luca F Abstract Chondrosarcoma is the second most common malignant tumor of the bone with an incidence of 1 in 200.000 per year. Axial skeleton is frequently involved showing poorer oncological outcomes than appendicular...
Rare Cancers
2d
Metastasis to gluteal muscle from high grade transitional cell carcinoma of bladder. Report of a case and review of literature.
Related ArticlesMetastasis to gluteal muscle from high grade transitional cell carcinoma of bladder. Report of a case and review of literature. Pathologica. 2018 Mar;110(1):78-81 Authors: Spinelli M, Gillibrand R Abstract High grade bladder malignancies have tendency to local and distant invasion. The most commonly involved sites are lymph nodes, lungs, bone and liver. Muscle metastases are generally rare and have been described in few cases of Genito-Urinary...
Rare Cancers
2d
Metastatic malignant melanoma to the gallbladder. Case report and review of the literature.
Related ArticlesMetastatic malignant melanoma to the gallbladder. Case report and review of the literature. Pathologica. 2018 Mar;110(1):68-71 Authors: Riva G, Villanova M, Eccher A, Luchini C, Motta F, Bernasconi R, Barbareschi M Abstract Solitary metastasis of malignant melanoma (MM) to the gallbladder (GB) is rare and generally originates from skin melanoma. MM is a neoplasm with an often unpredictable course and metastases can potentially affecting...
Rare Cancers
2d
Cytological features of hepatoid adenocarcinoma of the gallbladder: A case report with immunocytochemical analyzes.
Related ArticlesCytological features of hepatoid adenocarcinoma of the gallbladder: A case report with immunocytochemical analyzes. Diagn Cytopathol. 2018 Aug;46(8):711-715 Authors: Yoshioka S, Ishida M, Okano K, Sandoh K, Ebisu Y, Miyasaka C, Yamamoto T, Ryota H, Satoi S, Tsuta K Abstract Hepatoid adenocarcinoma is defined as an extrahepatic malignant neoplasm showing morphological and immunohistochemical resemblance of hepatocellular carcinoma. The...
Rare Cancers
2d
Fine-needle aspiration of tubulocystic renal cell carcinoma.
Related ArticlesFine-needle aspiration of tubulocystic renal cell carcinoma. Diagn Cytopathol. 2018 Aug;46(8):707-710 Authors: Renshaw AA, Gould EW Abstract We report two cases of tubulocystic renal cell carcinoma, a rare renal tumor the cytology of which has not been previously reported. Both aspirates were cellular and contained large sheets of cells with abundant granular cytoplasm, distinct cell borders and intracellular windows, distinct to prominent...
Rare Cancers
2d
Utility of autopsy brain imprint and squash cytology for detection of lymphoma/leukemia emboli in select patients presenting with rapid decline in mental status.
Related ArticlesUtility of autopsy brain imprint and squash cytology for detection of lymphoma/leukemia emboli in select patients presenting with rapid decline in mental status. Diagn Cytopathol. 2018 Aug;46(8):694-697 Authors: Kumarapeli AR, Gokden M Abstract Central nervous system (CNS) hematologic malignancies, whether primary or secondary, are uncommon and their clinical presentations vary. Intravascular lymphoma (IVL) is a very rare, aggressive...
Rare Cancers
2d
Effusion-based lymphoma with morphological regression but with clonal genetic features after aspiration.
Related ArticlesEffusion-based lymphoma with morphological regression but with clonal genetic features after aspiration. Diagn Cytopathol. 2018 Aug;46(8):685-689 Authors: Tsai MC, Kuo CC, Su YZ, Hsieh YC, Chuang SS Abstract Effusion-based lymphoma (EBL) is a rare but distinct entity of large B-cell lymphoma in effusion without association with human herpes virus-8 (HHV-8). Spontaneous regression after pleurocentesis has been observed; but to our knowledge,...
Rare Cancers
2d
An extremely rare giant skin cirsoid angioma with brain compression.
Related ArticlesAn extremely rare giant skin cirsoid angioma with brain compression. Neurology. 2018 03 06;90(10):481 Authors: Chen H, Lan Z, Xu J PMID: 29507133 [PubMed - indexed for MEDLINE]
Rare Cancers
2d
Contemporary management of patients with penile cancer and lymph node metastasis.
Related ArticlesContemporary management of patients with penile cancer and lymph node metastasis. Nat Rev Urol. 2017 Jun;14(6):335-347 Authors: Leone A, Diorio GJ, Pettaway C, Master V, Spiess PE Abstract Penile cancer is a rare disease that causes considerable physical and psychological patient morbidity, especially at advanced stages. Patients with low-stage nodal metastasis can achieve durable survival with surgery alone, but those with extensive...
Rare Cancers
2d
Photobiomodulation therapy and NMES improve muscle strength and jumping performance in young volleyball athletes: a randomized controlled trial study in Brazil
Abstract The purpose of this study was to investigate the effectiveness of adding photobiomodulation therapy and neuromuscular electrical stimulation (NMES) to volleyball athletes’ training, focusing on muscle strength and jumping skills. Thirty-six athletes were randomly placed into three groups: control, photobiomodulation therapy, and NMES. The athletes trained to improve their muscle strength and jumping skills. The athletes in the photobiomodulation therapy group were submitted...
Laser
21h

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