Researchers used microCT to study and re-study arthropod fossils from the early Cambrian in the Chengjiang biota in the Yunnan Province of China. Their latest study shows with unprecedented clarity the head morphology of the species Leanchoilia illecebrosa and demonstrates the presence of a labrum thus supporting the hypothesis that megacheirans are distant relatives of modern chelicerates (e.g. horseshoe crabs, scorpions and spiders).
Thu Jun 25, 2020 21:48
Sled dogs are much older and have adapted to Arctic conditions much earlier than previously thought. Researchers show that ancestors of modern sled dogs have worked and lived with humans for over 9,500 years.
Thu Jun 25, 2020 21:48
The outbreak of COVID-19 in the United States coincided with the season during which publicly traded companies hold their Annual General Meetings (AGM). As a result, I was able to attend this year’s shareowner meeting of The Coca-Cola Company (TCCC) while sitting in my kitchen in upstate New York. Like many other companies, TCCC canceled its in-person meeting and moved the event online. [pquote]The AGM nonetheless provided a means for gathering a diverse public around matters of concern and giving...
Fri Jun 26, 2020 21:30
Publication date: Available online 25 June 2020Source: Annales de Chirurgie Plastique EsthétiqueAuthor(s): P. Gagnieur, S. Rasteau, J.B. Caruhel, A. Louvrier, N. Sigaux
Fri Jun 26, 2020 20:48
Publication date: Available online 24 June 2020Source: Annales de Chirurgie Plastique EsthétiqueAuthor(s): C.-S. Bich, M. Brachet, A. Baus, A. Duhoux, P. Duhamel, É. Bey
Thu Jun 25, 2020 17:15
A method for delivering neural stem cells, adaptable for injecting solutions or suspensions, through the common carotid artery (mouse) or external carotid artery (rat) after ischemic stroke is reported. Injected cells are distributed broadly throughout the brain parenchyma and can be detected up to 30 d after delivery.
Fri Jun 26, 2020 20:36
We introduce an inner tube approach to the cuff technique for mouse cervical heterotopic heart transplantation to help evert the vessel over the cuff. We found that cooperation between two experienced surgeons markedly shortens the operation time.
Fri Jun 26, 2020 20:36
A protocol for graphene-assisted growth of high-quality AlN films on nano-patterned sapphire substrate is presented.
Thu Jun 25, 2020 19:39
A significant proportion of patients with severe asthma may also suffer from nasal polyposis, which is commonly defined as chronic rhinosinusitis with nasal polyps (CRSwNP), the presence of which may adversely...
Fri Jun 26, 2020 03:00
Summary Background Previous studies on neoadjuvant therapy for BRCA1-driven ovarian cancer (OC) demonstrated higher efficacy of mitomycin C plus cisplatin combination as compared to standard drug schemes. These data call for evaluation of the utility of this regimen for the treatment of recurrent BRCA1-associated OC. Methods The study included 12 BRCA1 germ-line mutation carriers, whose disease relapsed after one (n = 4) or two (n = 8) lines of chemotherapy. The patients received...
Fri Jun 26, 2020 03:00
Corrections are needed to the original version of this article. In Table 2, the “Odds ratio” of the variables “Lower lobe vs. Upper lobe” and “≥26 vs. <26” should be 2.250 instead of 2250 and 2.250 instead of 2.25.
Fri Jun 26, 2020 03:00
Due to wrong coding usage, the
Fri Jun 26, 2020 03:00
Abstract We present a new wave-type model of saltatory conduction in myelinated axons. Poor conductivity in the neuron cytosol limits electrical current signal velocity according to cable theory, to 1–3 m/s, whereas saltatory conduction occurs with a velocity of 100–300 m/s. We propose a wave-type mechanism for saltatory conduction in the form of the kinetics of an ionic plasmon-polariton being the hybrid of the electro-magnetic wave and of the synchronized ionic plasma oscillations...
Thu Jun 25, 2020 03:00
The cover image is based on the Correspondence: Our Experience* Using virtual reality in audiological training: Our experience in 22 otolaryngology residents by Charles Aussedat et al., https://doi.org/10.1111/coa.13554.
Sun Jun 21, 2020 19:11
Abstract Maize MZIR 098 was developed to confer tolerance to glufosinate‐ammonium‐containing herbicides and resistance to certain coleopteran pests. The molecular characterisation data and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the identified differences in the agronomic/phenotypic and compositional characteristics tested between maize MZIR 098 and its conventional counterpart needs further assessment, except for neutral detergent fibre (NDF...
Fri Jun 26, 2020 17:56
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on the assessment of the application for renewal of authorisation of Actisaf® Sc 47 (Saccharomyces cerevisiae CNCM I‐4407) as a zootechnical additive for calves for rearing. The applicant has provided evidence that the additive currently in the market complies with the existing conditions of authorisation. There is...
Fri Jun 26, 2020 17:56
Abstract The EFSA Panel on Plant Health performed a pest categorisation of Ripersiella hibisci (Hemiptera: Rhizoecidae) for the EU . R. hibisci occurs in Japan, China and Taiwan and has spread to the USA : Florida, Hawaii and the territory of Puerto Rico. R. hibisci is a polyphagous mealybug recorded feeding on roots of monocotyledonous and dicotyledonous plants. Root damage reduces nutrient and water uptake, retards plant growth and may cause leaves to wilt or discolour, heavily infested plants...
Thu Jun 25, 2020 13:57
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on the safety and efficacy of TechnoSpore® (Bacillus coagulans DSM 32016), when used as a zootechnical additive for piglets (suckling and weaned), other growing Suidae, chickens for fattening, other poultry for fattening and ornamental birds. The bacterial species present in the additive is considered suitable for the...
Thu Jun 25, 2020 13:57
Abstract Treason is one of the most serious legal offences that there are, in most if not all jurisdictions. Laws against treason are rooted in deep-seated moral revulsion about acts which, in the political realm, are paradigmatic examples of breaches of loyalty. Yet, it is not altogether clear what treason consists in: someone’s traitor is often another’s loyalist. In this paper, my aim is twofold: to offer a plausible conceptual account of treason, and to partly rehabilitate...
Fri Jun 26, 2020 03:00
The National Aeronautics and Space Administration (NASA) has set an exciting, yet ambitious timeline to get us back to the moon by 2024! But instead of merely planting a flag, playing a round of golf, and collecting some rocks to bring home, NASA hopes to establish a permanent lunar base that will eventually act as the launching point for crewed missions to Mars. If humans are to settle on the moon en route to exploring the “final frontier,” they’ll also need to figure out how to perform...
Fri Jun 26, 2020 17:38
GTX Medical, a medtech company with offices in The Netherlands and Switzerland, has announced that it received Breakthrough Device Designation for the Go-2 system, an implant that provides targeted epidural spinal stimulation therapy for patients with spinal cord injuries. The device aims to allow such patients to regain leg motor function and neurological control. At present, patients with lower limb paralysis caused by traumatic spinal cord injuries have limited options in terms...
Thu Jun 25, 2020 21:34
Sweat excreted by the skin contains important biomarkers for a number of diseases, as well as being a critical parameter in athletic performance, overall body function, and even an early warning indicator of an oncoming illness. Measuring sweat output and its chemical composition, in an accurate and easily administered way, has been a challenge. Athletes and others would benefit from a wearable patch that can be stuck near sweat glands to continuously measure pH levels, glucose, salt...
Thu Jun 25, 2020 19:43
Publication date: August 2020Source: Journal of Human Evolution, Volume 145Author(s): Marina Martínez de Pinillos, Laura Martín-Francés, José María Bermúdez de Castro, Cecilia García-Campos, Mario Modesto-Mata, María Martinón-Torres, Amélie Vialet
Fri Jun 26, 2020 17:15
Publication date: August 2020Source: Journal of Human Evolution, Volume 145Author(s): Matthew M. Skinner, Meave G. Leakey, Louise N. Leakey, Fredrick K. Manthi, Fred Spoor
Fri Jun 26, 2020 17:15
Publication date: Available online 25 June 2020Source: Clinical NeurophysiologyAuthor(s): Mark H. Myers, Akaash Padmanabha, Gavin M. Bidelman, James W. Wheless
Fri Jun 26, 2020 16:35
Publication date: Available online 25 June 2020Source: Clinical NeurophysiologyAuthor(s): Kei Yanai, Seijiro Shimada, Naoto Kunii, Megumi Takasago, Kazuhiko Takabatake, Nobuhito Saito
Fri Jun 26, 2020 16:35
Publication date: Available online 25 June 2020Source: Clinical NeurophysiologyAuthor(s): Roy Tzur, Marcelo David, Jeremy Barron, Efraim Jaul, Oded Meiron
Thu Jun 25, 2020 13:52
Publication date: Available online 25 June 2020Source: Clinical NeurophysiologyAuthor(s): Giuseppe Granata, Francesco Iodice, Benedetto Falsini, Paolo Maria Rossini
Thu Jun 25, 2020 13:52
Publication date: Available online 25 June 2020Source: Clinical NeurophysiologyAuthor(s): Hiroyuki Kidokoro, Hiroyuki Yamamoto, Tetsuo Kubota, Mitsuo Motobayashi, Yusaku Miyamoto, Tomohiko Nakata, Kyoko Takano, Naoko Shiba, Yu Okai, Masaharu Tanaka, Yoko Sakaguchi, Yuki Maki, Masahiro Kawaguchi, Takeshi Suzuki, Kazuhiro Muramatsu, Jun Natsume
Thu Jun 25, 2020 13:52
Publication date: Available online 24 June 2020Source: Clinical NeurophysiologyAuthor(s): Rui Feng, N.U. Farrukh Hameed, Jie Hu, Liqin Lang, Juanjuan He, Dongyan Wu, Zhen Fan, Shize Jiang, Qinglong Guo, Fengtao Liu, Yiting Mao, Ce Li, Bing Sun, Liang Chen, Li Pan
Thu Jun 25, 2020 13:52
Publication date: Available online 24 June 2020Source: Clinical NeurophysiologyAuthor(s): Davide Giampiccolo, Luigi Cattaneo, Federica Basaldella, Giuseppe Kenneth Ricciardi, Francesco Sala
Thu Jun 25, 2020 13:52
Publication date: Available online 24 June 2020Source: Clinical NeurophysiologyAuthor(s): Sahar F. Zafar, Edilberto Amorim, Craig A. Williamsom, Jing Jin, Emily J. Gilmore, Hiba A. Haider, Christa Swisher, Aaron Struck, Eric S. Rosenthal, Marcus Ng, Sarah Schmitt, Jong W. Lee, M. Brandon Westover
Thu Jun 25, 2020 13:52
Publication date: Available online 24 June 2020Source: Clinical NeurophysiologyAuthor(s): Bernhard A. Sabel, Andrea Antal
Thu Jun 25, 2020 13:52
Thu Jun 25, 2020 19:08
Thu Jun 25, 2020 13:34
Thu Jun 25, 2020 13:18
Thu Jun 25, 2020 11:46
Objectives: The value of adjuvant chemotherapy in T2N0M0 non–small-cell lung cancer (NSCLC) is unclear. Some current guidelines suggest adjuvant chemotherapy be considered for patients with tumors ≥4 cm. Prior population-based evaluations lacked lung cancer-specific survival (LCSS) and health insurance status. The authors aimed to identify predictors of adjuvant chemotherapy use and assess its real-world benefit in T2N0M0 NSCLC. Materials and Methods: The authors included patients who underwent...
Fri Jun 26, 2020 16:29
Background: Conditional survival (CS) is a relevant prognostic measure and may be particularly important for young adult patients with colorectal cancer (CRC), whose incidence is rising. We sought to compare CS among young versus older adults with CRC. Methods: Patients diagnosed with CRC between 2004 and 2010 were identified from the Surveillance, Epidemiology, and End Results registry. Smoothed yearly hazards of death due to CRC, other causes and any cause were estimated, stratified by...
Fri Jun 26, 2020 16:29
Aim/Objectives/Background: The American College of Radiology (ACR) and the American Society for Radiation Oncology (ASTRO) have jointly developed the following practice parameter for image-guided radiation therapy (IGRT). IGRT is radiation therapy that employs imaging to maximize accuracy and precision throughout the entire process of treatment delivery with the goal of optimizing accuracy and reliability of radiation therapy to the target, while minimizing dose to normal tissues. Methods: ...
Fri Jun 26, 2020 16:29
Background: Trastuzumab improves therapeutic outcomes among patients with human epidermal growth factor receptor 2–positive breast cancer (BC). However, it is associated with a risk of treatment-induced cardiotoxicity. The aims of this study were to determine the frequency of trastuzumab-induced cardiotoxicity (TIC) in Tunisian patients, to study the effects of trastuzumab on cardiac biomarkers and echocardiographic parameters using the speckle tracking technique and to identify risk factors of...
Fri Jun 26, 2020 16:29
Objectives: Previous prostate stereotactic body radiation therapy studies delivered uniform doses of 35 to 40 Gy/5 fx. Attempts at uniform dose escalation to 50 Gy caused high rates of gastrointestinal (GI) toxicity. We hypothesize that heterogeneous dose escalation to regions nonadjacent to sensitive structures (urethra, rectum, and bladder) is safe and efficacious. Materials and Methods: Patients were enrolled on a prospective pilot study. The primary endpoint was treatment-related GI and...
Fri Jun 26, 2020 16:29
No abstract available
Fri Jun 26, 2020 16:29
Introduction: Randomized clinical trials have shown combination therapy to be superior in progression-free survival (PFS) rates when compared with sunitinib alone. However, there have been no direct comparisons among the combination strategies making it unclear as to which may be the preferred option. We performed a network meta-analysis of the combination therapy (immune checkpoint inhibitor plus axitinib or bevacizumab) used in metastatic renal cell carcinoma (mRCC) and provided a rank order...
Fri Jun 26, 2020 16:29
Objectives: African American (AA) women with breast cancer (BrCA) have higher mortality than any other race. Differential mortality has been attributed to nonadherence to endocrine therapy (ET). ET can lower the risk of dying by one third; yet 50% to 75% of all women are nonadherent to ET. Despite the wealth of research examining adherence to ET, understanding which groups of women at risk for poor adherence is not well established. The aim of this investigation was to describe ET adherence by...
Fri Jun 26, 2020 16:29
Objectives: SLC-0111 is an ureido-substituted benzenesulfonamide small molecule inhibitor of carbonic anhydrase IX. The objectives of this first-in-human Phase 1 study were to determine the safety and tolerability of SLC-0111 in patients with advanced solid tumors and to establish the recommended Phase 2 dose for future clinical investigations. Materials and Methods: Using a 3+3 design, dose escalation started at 500 mg oral daily dosing of SLC-0111 in cohort 1 and increased to 1000 and 2000 mg...
Fri Jun 26, 2020 16:29
Objective: To examine the association among tyrosine kinase inhibitor (TKI) out-of-pocket costs, adherence, and health care costs and utilization in a large group of commercially insured patients with chronic myeloid leukemia (CML). Materials and Methods: Patients with CML aged 18 to 64 years were identified using IBM MarketScan Commercial Database between April 1, 2011 and December 31, 2014. Patients were required to be continuously enrolled 3 months before and 12 months after TKI (imatinib,...
Fri Jun 26, 2020 16:29
Objectives: A total of 30% to 40% of soft tissue sarcoma (STS) patients develop major wound complications (MWCs) after preoperative radiation (preRT). The optimal preRT-surgery interval and its association with MWCs is unknown. This study investigated whether a longer preRT-surgery interval is associated with fewer MWCs compared with historical controls. Methods: All patients treated by a single surgeon after preRT with limb-sparing wide resection for extremity and trunk STS were retrospectively...
Fri Jun 26, 2020 16:29
Objective: We aimed to explore possible drivers for urban-rural disparities in colon cancer outcomes in a single-payer health care system where all patients had access to universal health care coverage. Methods: Patients diagnosed with stage II/III colon cancer between 2004 and 2015 in Alberta, Canada were reviewed. On the basis of postal code, patients were categorized as living in urban, rural, or suburban areas based on travel distance to the cancer center. Kaplan-Meier methods and Cox...
Fri Jun 26, 2020 16:29
Abstract Background Intrathecal and intravenous chemotherapy, specifically methotrexate, might contribute to neural microstructural damage. Objective To assess, by diffusion tensor imaging, microstructural integrity of white matter in paediatric patients with acute lymphoblastic leukaemia (ALL) following intrathecal and intravenous chemotherapy. ...
Fri Jun 26, 2020 03:00
Abstract Background Image sharpness is commonly degraded on cardiac CT images reconstructed using iterative reconstruction algorithms. Objective To compare the image quality of cardiac CT between raw-data-based and model-based iterative reconstruction algorithms developed by the same CT vendor in children and young adults with congenital heart disease....
Fri Jun 26, 2020 03:00
Abstract Whole-body magnetic resonance imaging (MRI) is increasingly being used for a number of indications. Our aim was to review and describe indications and scan protocols for diagnostic value of whole-body MRI for multifocal disease in children and adolescents, we conducted a systematic search in Medline, Embase and Cochrane for all published papers until November 2018. Relevant subject headings and free text words were used for the following concepts: 1) whole-body, 2) magnetic...
Thu Jun 25, 2020 03:00
Abstract Background Ultrasound shear wave elastography (SWE) measures liver stiffness noninvasively, but few studies have defined cutoff values for detecting liver fibrosis in pediatric patients using 2-D ultrasound SWE. Objective To evaluate the diagnostic performance of 2-D ultrasound SWE and define cutoff values for liver fibrosis in pediatric patients,...
Thu Jun 25, 2020 03:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00633E, MinireviewRebecca L Pinals, Linda Chio, Francis Ledesma, Markita LandryUnpredictable and uncontrollable protein adsorption on nanoparticles remains a considerable challenge to achieving effective application of nanotechnologies within biological environments. Nevertheless, engineered nanoparticles offer unprecedented functionality and control in probing...The content of this RSS Feed (c) The Royal Society of Chemistry
Fri Jun 26, 2020 02:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN01036G, PaperHoi-Ting Wu, Ryan JulianRecent studies have illuminated connections between spontaneous chemical reactions that cause isomerization at specific protein residues and various age-related diseases including cataracts and Alzheimer’s. These discoveries provide impetus for better...The content of this RSS Feed (c) The Royal Society of Chemistry
Thu Jun 25, 2020 02:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00475H, PaperKun Zhang, Ting-Ting Chen, Yin-Jing Shen, Zhuo-Ran Yang, Yan Huang, Shishen Zhang, Jiadan Xue, Benxia LiThe development of inexpensive, selective and rapid-response chemosensors for detecting Cs+ of waste water is highly desirable in the nuclear power industry. Here we demonstrate an efficient Cs+ optical sensor...The content of this RSS Feed (c) The Royal Society of Chemistry
Thu Jun 25, 2020 02:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00961J, PaperBenjamin E Valley, Anne D Crowell, Tony Ladd, Jason E ButlerWe report separation of genomic DNA (48 kbp) from bovine serum albumin (BSA) by the electro-hydrodynamic coupling between a pressure-driven flow and a parallel electric field. Electro-hydrodynamic extraction exploits this...The content of this RSS Feed (c) The Royal Society of Chemistry
Thu Jun 25, 2020 02:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00986E, PaperKazuki Bando, Zhiqiang Zhang, Duncan Graham, Karen Faulds, Katsumasa Fujita, Satoshi KawataPlasmonic Ag nano-assembles moving in a living cell were employed to visualize the spatiotemporal change of intracellular pH by surface-enhanced Raman scattering. Ag nano-assembles were functionalized by 4-mercaptobenzoic acid (p-MBA)...The content of this RSS Feed (c) The Royal Society of Chemistry
Thu Jun 25, 2020 02:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00768D, PaperJiaqian Lou, Yue Cao, Youjia Yu, Li Hu, Zhengsheng Mao, Ping Huang, Xin Hua, Feng ChenSudden cardiac death (SCD), one of the most common causes of human death, has become a major health and social problem. The postmortem diagnosis and prevention of SCD remain primary...The content of this RSS Feed (c) The Royal Society of Chemistry
Thu Jun 25, 2020 02:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00818D, PaperMichael C Bagley, Crystal L Pace, Mans Ekelof, David MuddimanWe report the spatially resolved metabolic profiling of cherry tomatoes using infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI), a mass spectrometry imaging (MSI) technique that operates at ambient conditions and...The content of this RSS Feed (c) The Royal Society of Chemistry
Thu Jun 25, 2020 02:00
Related Articles Spectrum of Imaging Findings on Chest Radiographs, US, CT, and MRI Images in Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with COVID-19. Radiology. 2020 Jun 25;:202543 Authors: Hameed S, Elbaaly H, Reid CEL, Santos RMF, Shivamurthy V, Wong J, Jogeesvaran KH Abstract This case series examines the spectrum of imaging findings on chest radiographs, US, CT, and MRI images in 35 children admitted to a tertiary...
Fri Jun 26, 2020 15:55
Related Articles Cervical Spinal Cord Lesions and Atrophy versus Brain Measures in Explaining Physical Disability in Multiple Sclerosis. Radiology. 2020 Jun 23;:202304 Authors: Zivadinov R, Bergsland N PMID: 32579091 [PubMed - as supplied by publisher]
Thu Jun 25, 2020 16:04
Related Articles Deep Learning Improves Predictions of the Need for Total Knee Replacement. Radiology. 2020 Jun 23;:202332 Authors: Richardson ML PMID: 32579090 [PubMed - as supplied by publisher]
Thu Jun 25, 2020 16:04
No abstract available
Fri Jun 26, 2020 15:03
No abstract available
Fri Jun 26, 2020 15:03
BACKGROUND Preoperative acetaminophen and carbohydrate loading has been shown to improve the functional recovery of surgical patients. OBJECTIVE To determine the effects of preoperative acetaminophen and carbohydrates on functional outcomes and the use of pain medications after surgery in patients undergoing Mohs Micrographic Surgery (MMS) for nonmelanoma skin cancer (NMSC). MATERIALS AND METHODS One hundred patients treated with MMS for NMSC at an academic center were randomized into...
Fri Jun 26, 2020 15:03
BACKGROUND With the rising popularity of dermal fillers, the number of complications associated with fillers has increased. OBJECTIVE To identify and review reports of adverse events involving cosmetic injectable soft-tissue fillers from the FDA Manufacturer and User Facility Device Experience (MAUDE) database from June 1993 to August 2014. MATERIALS AND METHODS The authors conducted a search of adverse events within the U.S. Food and Drug Administration database that involved injectable...
Fri Jun 26, 2020 15:03
BACKGROUND Antibiotic use associated with Mohs surgery is increasing. OBJECTIVE To understand variation in practice patterns and factors associated with antibiotic use. MATERIALS AND METHODS The authors conducted a retrospective cohort study of antibiotic use among patients treated with Mohs micrographic surgery between July 1, 2013, and June 30, 2017, at an academic medical center. Multivariate logistic regression was used to evaluate for associations between antibiotic prescribing...
Fri Jun 26, 2020 15:03
No abstract available
Fri Jun 26, 2020 15:03
BACKGROUND Mohs micrographic surgery (MMS) relies on complete frozen tissue sections for the unique combination of high cure rates and tissue preservation. OBJECTIVE To quantify and characterize the tissue sectioning process in MMS. MATERIALS AND METHODS Two hundred eighty-four tissue blocks were analyzed. The histotechnician measured the depth cut into the tissue block for every section placed on the slide. The surgeon identified complete sections. RESULTS First-stage complete...
Fri Jun 26, 2020 15:03
BACKGROUND Recommendations on when to perform sentinel lymph node (SLN) biopsy in cutaneous squamous cell carcinoma (cSCC) are lacking despite the tumor's clear predilection for lymphatic spread. OBJECTIVE To analyze the frequency of SLN metastasis in published series of cSCC in the context of the eighth edition of the American joint Committee on Cancer (AJCC-8) and the Brigham and Women's Hospital (BWH) staging criteria. METHODS Systematic review of studies of patients with cSCC who...
Fri Jun 26, 2020 15:03
BACKGROUND Although there is a large body of evidence demonstrating the safety and efficacy of Mohs micrographic surgery (MMS) in adults, little is known regarding the safety and efficacy of MMS in children and adolescents. METHODS The authors searched all publications from 1993 to 2018 reporting on the use of MMS for the treatment of cutaneous neoplasms in patients aged 0 to 18 years. Patient demographics, surgical characteristics, outcomes, and complications were extracted from each report. ...
Fri Jun 26, 2020 15:03
No abstract available
Fri Jun 26, 2020 15:03
BACKGROUND Understanding factors that influence people to use sunscreen would allow clinicians to counsel patients in a way that is influential. Perceived efficacy of sunscreen has been associated with sunscreen use, but it is unclear whether the degree of efficacy is important. OBJECTIVE To determine whether larger perceived efficacy of sunscreen (larger skin cancer risk reduction) is associated with increased sunscreen use. MATERIALS AND METHODS A cohort of 131 patients with a history...
Fri Jun 26, 2020 15:03
No abstract available
Fri Jun 26, 2020 15:03
BACKGROUND Medium-sized defects of the scalp, temple, and forehead can be challenging to reconstruct in an aesthetic fashion. The author proposes the use of a hybrid flap that is at times bipedicled, perforator, and/or axially supplied. OBJECTIVE To describe the author's experience with the bridge flap and its various subtypes. METHODS An IRB-approved retrospective database review of all bridge flaps was performed at all Skin Cancer Institute facilities. The design and method of dissection...
Fri Jun 26, 2020 15:03
No abstract available
Fri Jun 26, 2020 15:03
No abstract available
Fri Jun 26, 2020 15:03
BACKGROUND Reconstruction of large nasal surgical defects often warrant the use of mucosal flaps to repair the inner lining. This often presents a challenge for surgical reconstruction. OBJECTIVE To describe a unique reconstructive option for the repair of large surgical wounds that necessitate mucosal nasal lining. MATERIALS AND METHODS This study is a retrospective review of 10 patients who underwent surgical reconstruction of large nasal and/or heminasal surgical defects following...
Fri Jun 26, 2020 15:03
BACKGROUND Understanding the subjects' perspective is critical for successfully treating upper facial lines. OBJECTIVE To understand subjects' self-perception and overall satisfaction after onabotulinumtoxinA treatment for forehead and glabellar lines. METHODS This analysis pooled data from two 12-month, pivotal phase 3 studies in which toxin-naive subjects received onabotulinumtoxinA 40 U or placebo for treatment of upper facial lines. OnabotulinumtoxinA was administered as 0.1-mL injections...
Fri Jun 26, 2020 15:03
BACKGROUND Few publications have addressed nasal valve (NV) insufficiency as a complication of Mohs micrographic surgery. OBJECTIVE To comprehensively review the literature and further characterize the causes, prevalence, evaluation, and management of NV insufficiency as it relates to cutaneous oncology. MATERIALS AND METHODS A PubMed search was completed to identify articles related to the NV in the context of Mohs micrographic surgery, cutaneous oncology, and reconstruction. RESULTS...
Fri Jun 26, 2020 15:03
No abstract available
Fri Jun 26, 2020 15:03
No abstract available
Fri Jun 26, 2020 15:03
No abstract available
Fri Jun 26, 2020 15:03
BACKGROUND The possible connection between hidradenitis suppurativa (HS) patients undergoing surgery and higher complications/recurrences has been implied, but inconsistent results reported. OBJECTIVE To assess the complication and recurrence rates for HS patients undergoing surgery and to evaluate whether known HS comorbidities and habits (smoking, obesity and diabetes) have an effect on the complication and recurrence rates. MATERIALS AND METHODS A systematic review was conducted by...
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