Related Articles Stanford type a aortic dissection with cerebral infarction: a rare case report. BMC Neurol. 2020 Jun 23;20(1):253 Authors: Wang J, Wu LR, Xie X Abstract BACKGROUND: Aortic dissection (AoD) is a disease with a high mortality rate. Its clinical manifestations are diverse and covert, which makes diagnosis and treatment challenging. Here, we report a very rare case of aortic dissection leading to bilateral cerebral cortex ischaemia...
Related Articles Neuroinflammation in Children With Infantile Spasms: A Prospective Study Before and After Treatment With Acthar Gel (Repository Corticotropin Injection). J Child Neurol. 2020 Jun 23;:883073820932710 Authors: Chugani HT, Kumar A Abstract The selective effectiveness of adrenocorticotropic hormone (ACTH) in treating infantile spasms suggests an underlying neuroinflammation. Because neuroinflammation is mediated by activated microglia,...
Related Articles S(+)-(2E)-N-(2-Hydroxypropyl)-3-Phenylprop-2-Enamide (KM-568): A Novel Cinnamamide Derivative with Anticonvulsant Activity in Animal Models of Seizures and Epilepsy. Int J Mol Sci. 2020 Jun 19;21(12): Authors: Gunia-Krzyżak A, Żesławska E, Słoczyńska K, Żelaszczyk D, Sowa A, Koczurkiewicz-Adamczyk P, Popiół J, Nitek W, Pękala E, Marona H Abstract Epilepsy is one of the most frequent neurological disorders affecting about 1%...
Related Articles Peer support for frequent users of inpatient mental health care in Uganda: protocol of a quasi-experimental study. BMC Psychiatry. 2019 11 29;19(1):374 Authors: Ryan GK, Kamuhiirwa M, Mugisha J, Baillie D, Hall C, Newman C, Nkurunungi E, Rathod SD, Devries KM, De Silva MJ, Mpango R Abstract BACKGROUND: Reducing readmissions among frequent users of psychiatric inpatient care could result in substantial cost savings to under-resourced...
Related Articles Neurological Complications of Sturge-Weber Syndrome: Current Status and Unmet Needs. Pediatr Neurol. 2019 09;98:31-38 Authors: Luat AF, Juhász C, Loeb JA, Chugani HT, Falchek SJ, Jain B, Greene-Roethke C, Amlie-Lefond C, Ball KL, Davis A, Pinto A Abstract OBJECTIVE: We aimed to identify the current status and major unmet needs in the management of neurological complications in Sturge-Weber syndrome. METHODS: An expert...
Related Articles The nucleus reuniens of the thalamus sits at the nexus of a hippocampus and medial prefrontal cortex circuit enabling memory and behavior. Learn Mem. 2019 07;26(7):191-205 Authors: Dolleman-van der Weel MJ, Griffin AL, Ito HT, Shapiro ML, Witter MP, Vertes RP, Allen TA Abstract The nucleus reuniens of the thalamus (RE) is a key component of an extensive network of hippocampal and cortical structures and is a fundamental substrate...
Related Articles Impact of epilepsy and antiepileptic drugs on health and quality of life in Indian children. Epilepsy Behav. 2019 04;93:43-48 Authors: Nagabushana D, S PK, Agadi JB Abstract BACKGROUND AND OBJECTIVES: Epilepsy affects the physical, cognitive, emotional, social wellbeing, and thereby the overall quality of life (QOL). Epilepsy is the most prevalent neurological disorder in the pediatric age group with a prevalence of 3.13 to...
Related Articles Outcome after hemispherotomy in patients with intractable epilepsy: Comparison of techniques in the Italian experience. Epilepsy Behav. 2019 04;93:22-28 Authors: de Palma L, Pietrafusa N, Gozzo F, Barba C, Carfi-Pavia G, Cossu M, De Benedictis A, Genitori L, Giordano F, Russo GL, Marras CE, Pelliccia V, Rizzi S, Rossi-Espagnet C, Vigevano F, Guerrini R, Tassi L, Specchio N Abstract OBJECTIVE: The objective of the study was...
Related Articles Are psychogenic nonepileptic seizures risk factors for a worse outcome in patients with refractory mesial temporal epilepsy submitted to surgery? Results of a retrospective cohort study. Epilepsy Behav. 2019 04;93:12-15 Authors: Furlan AER, da Silva SC, Marques LHN, de Araujo Filho GM Abstract OBJECTIVE: The objective of this study was to verify if the presence of psychogenic nonepileptic seizures (PNES) could be a risk factor...
Mark above section as read
Related Articles Molecular therapeutic targets in non-small cell lung cancer. Expert Rev Anticancer Ther. 2020 Jun 25;: Authors: Sankar K, Gadgeel SM, Qin A Abstract INTRODUCTION: Several targetable genetic alterations have been identified in non-small cell lung cancers (NSCLC) and drugs targeting these alterations have been approved for the management of advanced NSCLC patients. Driver mutations with emerging clinical trial data include EGFR...
Mark above section as read
Related Articles Cell cycle regulation in NAFLD: when imbalanced metabolism limits cell division. Hepatol Int. 2020 Jun 22;: Authors: Caldez MJ, Bjorklund M, Kaldis P Abstract Cell division is essential for organismal growth and tissue homeostasis. It is exceptionally significant in tissues chronically exposed to intrinsic and external damage, like the liver. After decades of studying the regulation of cell cycle by extracellular signals, there...
Mark above section as read
Related Articles The Effects of an Ocular Direct Electrical Stimulation on Pattern-Reversal Electroretinogram. Front Neurosci. 2020;14:588 Authors: Blum MC, Hunold A, Solf B, Klee S Abstract Studies on transcranial current stimulation have shown that a direct current stimulation of the occipital cortex can influence the amplitude size of a visual evoked potential (VEP). The current direction (cathodal or anodal) determines whether the VEP amplitudes...
Related Articles Exploring the Promise of Flavonoids to Combat Neuropathic Pain: From Molecular Mechanisms to Therapeutic Implications. Front Neurosci. 2020;14:478 Authors: Uddin MS, Mamun AA, Rahman MA, Kabir MT, Alkahtani S, Alanazi IS, Perveen A, Ashraf GM, Bin-Jumah MN, Abdel-Daim MM Abstract Neuropathic pain (NP) is the result of irregular processing in the central or peripheral nervous system, which is generally caused by neuronal injury....
Related Articles Loss of Wwox Perturbs Neuronal Migration and Impairs Early Cortical Development. Front Neurosci. 2020;14:644 Authors: Iacomino M, Baldassari S, Tochigi Y, Kośla K, Buffelli F, Torella A, Severino M, Paladini D, Mandarà L, Riva A, Scala M, Balagura G, Accogli A, Nigro V, Minetti C, Fulcheri E, Zara F, Bednarek AK, Striano P, Suzuki H, Salpietro V Abstract Mutations in the WWOX gene cause a broad range of ultra-rare neurodevelopmental...
Related Articles Volitional Control of Piloerection: Objective Evidence and Its Potential Utility in Neuroscience Research. Front Neurosci. 2020;14:590 Authors: Katahira K, Kawakami A, Tomita A, Nagata N Abstract The volitional control of piloerection has been previously reported in a small subset of individuals. Although this ability may be useful to study the mechanism underlying piloerection, there is little existing research on this ability,...
Related Articles Non-invasive Neurophysiology in Learning and Training: Mechanisms and a SWOT Analysis. Front Neurosci. 2020;14:589 Authors: Tinga AM, de Back TT, Louwerse MM Abstract Although many scholars deem non-invasive measures of neurophysiology to have promise in assessing learning, these measures are currently not widely applied, neither in educational settings nor in training. How can non-invasive neurophysiology provide insight into...
Related Articles Accurate MR Image Registration to Anatomical Reference Space for Diffuse Glioma. Front Neurosci. 2020;14:585 Authors: Visser M, Petr J, Müller DMJ, Eijgelaar RS, Hendriks EJ, Witte M, Barkhof F, van Herk M, Mutsaerts HJMM, Vrenken H, de Munck JC, De Witt Hamer PC Abstract To summarize the distribution of glioma location within a patient population, registration of individual MR images to anatomical reference space is required....
Related Articles Behavioral and Neural Arguments of Motivational Influence on Decision Making During Uncertainty. Front Neurosci. 2020;14:583 Authors: Giustiniani J, Nicolier M, Teti Mayer J, Chabin T, Masse C, Galmès N, Pazart L, Trojak B, Bennabi D, Vandel P, Haffen E, Gabriel D Abstract The scientific world is increasingly interested in motivation, primarily due to the suspected impact on decision-making abilities, particularly in uncertain...
Related Articles Persistent Neurovascular Unit Dysfunction: Pathophysiological Substrate and Trigger for Late-Onset Neurodegeneration After Traumatic Brain Injury. Front Neurosci. 2020;14:581 Authors: Zhou Y, Chen Q, Wang Y, Wu H, Xu W, Pan Y, Gao S, Dong X, Zhang JH, Shao A Abstract Traumatic brain injury (TBI) represents one of the major causes of death worldwide and leads to persisting neurological deficits in many of the survivors. One of...
Gene Deregulation and Underlying Mechanisms in Spinocerebellar Ataxias With Polyglutamine Expansion.
Related Articles Gene Deregulation and Underlying Mechanisms in Spinocerebellar Ataxias With Polyglutamine Expansion. Front Neurosci. 2020;14:571 Authors: Niewiadomska-Cimicka A, Hache A, Trottier Y Abstract Polyglutamine spinocerebellar ataxias (polyQ SCAs) include SCA1, SCA2, SCA3, SCA6, SCA7, and SCA17 and constitute a group of adult onset neurodegenerative disorders caused by the expansion of a CAG repeat sequence located within the coding...
Related Articles Human Discrimination and Categorization of Emotions in Voices: A Functional Near-Infrared Spectroscopy (fNIRS) Study. Front Neurosci. 2020;14:570 Authors: Gruber T, Debracque C, Ceravolo L, Igloi K, Marin Bosch B, Frühholz S, Grandjean D Abstract Functional Near-Infrared spectroscopy (fNIRS) is a neuroimaging tool that has been recently used in a variety of cognitive paradigms. Yet, it remains unclear whether fNIRS is suitable...
Related Articles Quantitative Assessment of Pain Threshold Induced by a Single-Pulse Transcranial Magnetic Stimulation. Front Neurosci. 2020;14:559 Authors: Tani K, Hirata A, Tanaka S Abstract Transcranial magnetic stimulation (TMS) is commonly used in basic research to evaluate human brain function. Although scalp pain is a side effect, no studies have quantitatively assessed the TMS intensity threshold for inducing pain and whether sensitivity...
Related Articles LRRK2-Related Parkinson's Disease Due to Altered Endolysosomal Biology With Variable Lewy Body Pathology: A Hypothesis. Front Neurosci. 2020;14:556 Authors: Rivero-Ríos P, Romo-Lozano M, Fasiczka R, Naaldijk Y, Hilfiker S Abstract Mutations in the gene encoding for leucine-rich repeat kinase 2 (LRRK2) are associated with both familial and sporadic Parkinson's disease (PD). LRRK2 encodes a large protein comprised of a GTPase...
Related Articles MRI Features in a Rat Model of H-ABC Tubulinopathy. Front Neurosci. 2020;14:555 Authors: Garduno-Robles A, Alata M, Piazza V, Cortes C, Eguibar JR, Pantano S, Hernandez VH Abstract Tubulinopathies are a group of recently described diseases characterized by mutations in the tubulin genes. Mutations in TUBB4A produce diseases such as dystonia type 4 (DYT4) and hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC),...
Related Articles Forward to Bernstein: Movement Complexity as a New Frontier. Front Neurosci. 2020;14:553 Authors: Biryukova E, Sirotkina I Abstract The paper attempts to demonstrate that the "old-school" approach in motor control studies suggested over a century ago by I. M. Sechenov (1866/1968, 1901) and, later, N. A. Bernstein (1923, 1929, 1940, 1961) remains valid and relevant. Their methodology was to study the motor "periphery" in order...
Related Articles Editorial: Sonification, Perceptualizing Biological Information. Front Neurosci. 2020;14:550 Authors: Minciacchi D, Rosenboom D, Bravi R, Cohen EJ PMID: 32581690 [PubMed]
Related Articles Object-Based Analyses in FIJI/ImageJ to Measure Local RNA Translation Sites in Neurites in Response to Aβ1-42 Oligomers. Front Neurosci. 2020;14:547 Authors: Gamarra M, Blanco-Urrejola M, Batista AFR, Imaz J, Baleriola J Abstract Subcellular protein delivery is especially important in signal transduction and cell behavior, and is typically achieved by localization signals within the protein. However, protein delivery can also...
Related Articles Integrated Automatic Detection, Classification and Imaging of High Frequency Oscillations With Stereoelectroencephalography. Front Neurosci. 2020;14:546 Authors: Zhao B, Hu W, Zhang C, Wang X, Wang Y, Liu C, Mo J, Yang X, Sang L, Ma Y, Shao X, Zhang K, Zhang J Abstract Objective: During presurgical evaluation for focal epilepsy patients, the evidence supporting the use of high frequency oscillations (HFOs) for delineating the...
Related Articles Histological Correlates of Diffusion-Weighted Magnetic Resonance Microscopy in a Mouse Model of Mesial Temporal Lobe Epilepsy. Front Neurosci. 2020;14:543 Authors: Göbel-Guéniot K, Gerlach J, Kamberger R, Leupold J, von Elverfeldt D, Hennig J, Korvink JG, Haas CA, LeVan P Abstract Mesial temporal lobe epilepsy (MTLE) is the most common type of focal epilepsy. It is frequently associated with abnormal MRI findings, which are...
Related Articles Monitoring of Stimulus Evoked Murine Somatosensory Cortex Hemodynamic Activity With Volumetric Multi-Spectral Optoacoustic Tomography. Front Neurosci. 2020;14:536 Authors: Mc Larney B, Hutter MA, Degtyaruk O, Deán-Ben XL, Razansky D Abstract Sensory stimulation is an attractive paradigm for studying brain activity using various optical-, ultrasound- and MRI-based functional neuroimaging methods. Optoacoustics has been recently...
Related Articles Features of Postnatal Hippocampal Development in a Rat Model of Sporadic Alzheimer's Disease. Front Neurosci. 2020;14:533 Authors: Rudnitskaya EA, Kozlova TA, Burnyasheva AO, Tarasova AE, Pankova TM, Starostina MV, Stefanova NA, Kolosova NG Abstract Aging is the major risk factor of the most common (∼95% of cases) sporadic Alzheimer's disease (AD). Accumulating data indicate middle age as a critical period for the relevant pathological...
Related Articles Bsx Is Essential for Differentiation of Multiple Neuromodulatory Cell Populations in the Secondary Prosencephalon. Front Neurosci. 2020;14:525 Authors: Schredelseker T, Veit F, Dorsky RI, Driever W Abstract The hypothalamus is characterized by great neuronal diversity, with many neuropeptides and other neuromodulators being expressed within its multiple anatomical domains. The regulatory networks directing hypothalamic development...
Related Articles The Mammalian Diving Response: Inroads to Its Neural Control. Front Neurosci. 2020;14:524 Authors: Panneton WM, Gan Q Abstract The mammalian diving response (DR) is a remarkable behavior that was first formally studied by Laurence Irving and Per Scholander in the late 1930s. The DR is called such because it is most prominent in marine mammals such as seals, whales, and dolphins, but nevertheless is found in all mammals studied....
Related Articles Non-invasive Transcranial Electrical Stimulation in Movement Disorders. Front Neurosci. 2020;14:522 Authors: Ganguly J, Murgai A, Sharma S, Aur D, Jog M Abstract Dysfunction within large-scale brain networks as the basis for movement disorders is an accepted hypothesis. The treatment options for restoring network function are limited. Non-invasive brain stimulation techniques such as repetitive transcranial magnetic stimulation...
Related Articles Activation of the VPAC2 Receptor Impairs Axon Outgrowth and Decreases Dendritic Arborization in Mouse Cortical Neurons by a PKA-Dependent Mechanism. Front Neurosci. 2020;14:521 Authors: Takeuchi S, Kawanai T, Yamauchi R, Chen L, Miyaoka T, Yamada M, Asano S, Hayata-Takano A, Nakazawa T, Yano K, Horiguchi N, Nakagawa S, Takuma K, Waschek JA, Hashimoto H, Ago Y Abstract Clinical studies have shown that microduplications at 7q36.3,...
Related Articles Metformin Enhances Antidepressant/Antipsychotic Combination Therapy of Schizophrenia With Comorbid Depression in a Murine Model. Front Neurosci. 2020;14:517 Authors: Zhou C, Kong D, Xue R, Chen M, Li G, Xu Y, Liu S, Tian H, Zhuo C Abstract Comorbid depressive disorders confound the diagnosis and therapy of schizophrenia. Using a murine model incorporating both MK801 and chronic unpredictable mild stress exposures, we successfully...
Related Articles Machine Learning Representation of Loss of Eye Regularity in a Drosophila Neurodegenerative Model. Front Neurosci. 2020;14:516 Authors: Diez-Hermano S, Ganfornina MD, Vegas-Lozano E, Sanchez D Abstract The fruit fly compound eye is a premier experimental system for modeling human neurodegenerative diseases. The disruption of the retinal geometry has been historically assessed using time-consuming and poorly reliable techniques...
Related Articles Protracted Morphological Changes in the Corticospinal Tract Within the Cervical Spinal Cord After Intracerebral Hemorrhage in the Right Striatum of Mice. Front Neurosci. 2020;14:506 Authors: Ng ACK, Yao M, Cheng SY, Li J, Huang JD, Wu W, Leung GKK, Sun H Abstract Intracerebral hemorrhage (ICH) is associated with high morbidity and mortality rates. Currently, there is no promising treatment that improves prognosis significantly....
Related Articles Neural Mechanisms of Choice Diversification. Front Neurosci. 2020;14:502 Authors: Couwenberg LE, Boksem MAS, Sanfey AG, Smidts A Abstract When asked to select several options at once, people tend to choose a greater diversity of items than when they are asked to make these selections one at a time. Using functional magnetic resonance imaging (fMRI), we provide novel insight into the neural mechanisms underlying diversification...
Related Articles Nanotechnology: A Promising Approach for Delivery of Neuroprotective Drugs. Front Neurosci. 2020;14:494 Authors: Naqvi S, Panghal A, Flora SJS Abstract Central nervous system (CNS) disorders especially neurodegenerative disorders are the major challenge for public health and demand the great attention of researchers to protect people against them. In past few decades, different treatment strategies have been adopted, but their...
Related Articles Pre-dopa Deep Brain Stimulation: Is Early Deep Brain Stimulation Able to Modify the Natural Course of Parkinson's Disease? Front Neurosci. 2020;14:492 Authors: Porta M, Servello D, Zekaj E, Gonzalez-Escamilla G, Groppa S Abstract Deep brain stimulation (DBS) is an established therapy for the management of Parkinson's disease (PD). However, DBS is indicated as the disease progresses and motor complications derived from pharmacological...
Related Articles A Nomogram Model of Radiomics and Satellite Sign Number as Imaging Predictor for Intracranial Hematoma Expansion. Front Neurosci. 2020;14:491 Authors: Xu W, Ding Z, Shan Y, Chen W, Feng Z, Pang P, Shen Q Abstract Background: We aimed to construct and validate a nomogram model based on the combination of radiomic features and satellite sign number for predicting intracerebral hematoma expansion. Methods: A total of 129...
Related Articles The Mechanisms of Nuclear Proteotoxicity in Polyglutamine Spinocerebellar Ataxias. Front Neurosci. 2020;14:489 Authors: Lee D, Lee YI, Lee YS, Lee SB Abstract Polyglutamine (polyQ) spinocerebellar ataxias (SCAs) are the most prevalent subset of SCAs and share the aberrant expansion of Q-encoding CAG repeats within the coding sequences of disease-responsible genes as their common genetic cause. These polyQ SCAs (SCA1, SCA2, SCA3,...
Related Articles Periodicity Pitch Perception. Front Neurosci. 2020;14:486 Authors: Klefenz F, Harczos T Abstract This study presents a computational model to reproduce the biological dynamics of "listening to music." A biologically plausible model of periodicity pitch detection is proposed and simulated. Periodicity pitch is computed across a range of the auditory spectrum. Periodicity pitch is detected from subsets of activated auditory nerve...
Related Articles Applications of Resting-State fNIRS in the Developing Brain: A Review From the Connectome Perspective. Front Neurosci. 2020;14:476 Authors: Hu Z, Liu G, Dong Q, Niu H Abstract Early brain development from infancy through childhood is closely related to the development of cognition and behavior in later life. Human brain connectome is a novel framework for describing topological organization of the developing brain. Resting-state...
Related Articles Stress-Induced Microstructural Alterations Correlate With the Cognitive Performance of Rats: A Longitudinal in vivo Diffusion Tensor Imaging Study. Front Neurosci. 2020;14:474 Authors: Nagy SA, Vranesics A, Varga Z, Csabai D, Bruszt N, Bali ZK, Perlaki G, Hernádi I, Berente Z, Miseta A, Dóczi T, Czéh B Abstract Background: Stress-induced cellular changes in limbic brain structures contribute to the development of various psychopathologies....
Related Articles Application of Stem Cells in Stroke: A Multifactorial Approach. Front Neurosci. 2020;14:473 Authors: Singh M, Pandey PK, Bhasin A, Padma MV, Mohanty S Abstract Stroke has a debilitating effect on the human body and a serious negative effect on society, with a global incidence of one in every six people. According to the World Health Organization, 15 million people suffer stroke worldwide each year. Of these, 5 million die and...
Related Articles Phosphodiesterase 9A Inhibition Facilitates Corticostriatal Transmission in Wild-Type and Transgenic Rats That Model Huntington's Disease. Front Neurosci. 2020;14:466 Authors: Chakroborty S, Manfredsson FP, Dec AM, Campbell PW, Stutzmann GE, Beaumont V, West AR Abstract Huntington's disease (HD) results from abnormal expansion in CAG trinucleotide repeats within the HD gene, a mutation which leads to degeneration of striatal...
Related Articles Editorial: Bridging the Gap in Neuroelectronic Interfaces. Front Neurosci. 2020;14:457 Authors: Hofmann UG, Capadona JR PMID: 32581667 [PubMed]
Related Articles On the Possible Overestimation of Cognitive Decline: The Impact of Age-Related Hearing Loss on Cognitive-Test Performance. Front Neurosci. 2020;14:454 Authors: Füllgrabe C Abstract Individual differences and age-related normal and pathological changes in mental abilities require the use of cognitive screening and assessment tools. However, simultaneously occurring deficits in sensory processing, whose prevalence increases especially...
Related Articles Fetal Programming by Methyl Donors Modulates Central Inflammation and Prevents Food Addiction-Like Behavior in Rats. Front Neurosci. 2020;14:452 Authors: Cruz-Carrillo G, Montalvo-Martínez L, Cárdenas-Tueme M, Bernal-Vega S, Maldonado-Ruiz R, Reséndez-Pérez D, Rodríguez-Ríos D, Lund G, Garza-Ocañas L, Camacho-Morales A Abstract Fetal programming by hypercaloric intake leads to food addiction-like behavior and brain pro-inflammatory...
Related Articles Bloodletting Puncture at Hand Twelve Jing-Well Points Improves Neurological Recovery by Ameliorating Acute Traumatic Brain Injury-Induced Coagulopathy in Mice. Front Neurosci. 2020;14:403 Authors: Li B, Zhou X, Yi TL, Xu ZW, Peng DW, Guo Y, Guo YM, Cao YL, Zhu L, Zhang S, Cheng SX Abstract Traumatic brain injury (TBI) contributes to hypocoagulopathy associated with prolonged bleeding and hemorrhagic progression. Bloodletting...
Related Articles Multimodal MRI Longitudinal Assessment of White and Gray Matter in Different SPG Types of Hereditary Spastic Paraparesis. Front Neurosci. 2020;14:325 Authors: Montanaro D, Vavla M, Frijia F, Aghakhanyan G, Baratto A, Coi A, Stefan C, Girardi G, Paparella G, De Cori S, Totaro P, Lombardo F, Piccoli G, Martinuzzi A Abstract Hereditary spastic paraplegias (HSP) are a group of genetically and clinically heterogeneous neurologic...
Related Articles MVPA-Light: A Classification and Regression Toolbox for Multi-Dimensional Data. Front Neurosci. 2020;14:289 Authors: Treder MS Abstract MVPA-Light is a MATLAB toolbox for multivariate pattern analysis (MVPA). It provides native implementations of a range of classifiers and regression models, using modern optimization algorithms. High-level functions allow for the multivariate analysis of multi-dimensional data, including generalization...
Mark above section as read
Related Articles [Theory and practice of aging upon COVID-19 pandemic.] Adv Gerontol. 2020;33(2):397-408 Authors: Golubev AG, Sidorenko AV Abstract Never before in history, aging was such a significant factor for epidemics as it is now for the current COVID-19 pandemic, which features a drastic shift of mortality towards older ages. Our analysis of data on COVID-19-related mortality in Spain, Italy, and Sweden has shown that, in the range of...
Related Articles ATR-CHK1 pathway as a therapeutic target for acute and chronic leukemias. Cancer Treat Rev. 2020 May 16;88:102026 Authors: Boudny M, Trbusek M Abstract Progress in cancer therapy changed the outcome of many patients and moved therapy from chemotherapy agents to targeted drugs. Targeted drugs already changed the clinical practice in treatment of leukemias, such as imatinib (BCR/ABL inhibitor) in chronic myeloid leukemia (CML)...
Related Articles Metformin: (future) best friend of the radiation oncologist? Radiother Oncol. 2020 Jun 24;: Authors: Chevalier B, Pasquier D, Lartigau EF, Chargari C, Schernberg A, Jannin A, Mirabel X, Vantyghem MC, Escande A Abstract Several molecules are being investigated for their ability to enhance the anti-tumor effect of radiotherapy. The widely prescribed antidiabetic drug metformin has been suggested to possess anti-cancer activity;...
Related Articles A survey about the contents and features of oncology clinical pharmacy services and self-evaluations of the oncology pharmacists in China. J Clin Pharm Ther. 2020 Jun 26;: Authors: Wang Y, Dai Y, Yang J, Zhou H, Chen Z, Li G Abstract WHAT IS KNOWN AND OBJECTIVE: In China, with the increased number of oncology patients and use of novel antitumour drugs, the demand of oncology clinical pharmacy services is also growing. However,...
Related Articles Prediction of mucositis risk secondary to cancer therapy: a systematic review of current evidence and call to action. Support Care Cancer. 2020 Jun 26;: Authors: Wardill HR, Sonis ST, Blijlevens NMA, Van Sebille YZA, Ciorba MA, Loeffen EAH, Cheng KKF, Bossi P, Porcello L, Castillo DA, Elad S, Bowen JM, Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) ...
Related Articles Clinicopathological characteristics and prognosis analysis of ovarian metastases in colorectal cancer: a single-center experience. Int J Clin Oncol. 2020 Jun 26;: Authors: Zhou R, Liu Y, Wang Y, Huo X, Zhu J, Zhang T Abstract PURPOSE: This study aimed to improve the management of ovarian metastases (OM) in colorectal cancer (CRC) by evaluating the clinicopathological characteristics, therapeutic strategies, and prognostic factors...
Related Articles Nanoparticles in Colorectal Cancer Therapy: Latest In Vivo Assays, Clinical Trials, and Patents. AAPS PharmSciTech. 2020 Jun 26;21(5):178 Authors: Cabeza L, Perazzoli G, Mesas C, Jiménez-Luna C, Prados J, Rama AR, Melguizo C Abstract Colorectal cancer (CRC) is the third most common cancer worldwide. Its poor response to current treatment options in advanced stages and the need for efficient diagnosis in early stages call for...
Related Articles Histological intratumoral heterogeneity in pretreatment esophageal cancer biopsies predicts survival benefit from neoadjuvant chemotherapy: results from the UK MRC OE02 trial. Dis Esophagus. 2020 Jun 27;: Authors: Davarzani N, Hewitt LC, Hale MD, Melotte V, Nankivell M, Hutchins GGA, Cunningham D, Allum WH, Langley RE, Jolani S, Grabsch HI Abstract Despite the use of multimodal treatment, survival of esophageal cancer (EC) patients...
Related Articles Dose-effect relationships of holmium-166 radioembolization in colorectal cancer. J Nucl Med. 2020 Jun 26;: Authors: van Roekel C, Bastiaannet R, Smits MLJ, Bruijnen RC, Braat AJAT, de Jong HWAM, Elias SG, Lam MGEH Abstract INTRODUCTION: Radioembolization is a treatment option for colorectal cancer (CRC) patients with inoperable, chemorefractory hepatic metastases. Personalized treatment requires established dose thresholds....
Related Articles Pure Red Cell Aplasia Related to Parvovirus B19 Infection in Simultaneous Pancreas and Kidney Recipient: A Case Report. Transplant Proc. 2020 Jun 24;: Authors: Nowacka-Cieciura E, Karakulska-Prystupiuk E, Żuk-Wasek A, Lisik W, Basak GW, Durlik M Abstract A 42-year-old woman received a simultaneous pancreas and kidney transplantation (SPK). Immunosuppression consisted of tacrolimus modified release, prednisone, mycophenolate...
Related Articles A structural equation model to assess the pathways of body adiposity and inflammation status on dysmetabolic biomarkers via red cell distribution width and mean corpuscular volume: a cross-sectional study in overweight and obese subjects. Lipids Health Dis. 2020 Jun 26;19(1):154 Authors: Rondanelli M, Perna S, Alalwan TA, Cazzola R, Gasparri C, Infantino V, Perdoni F, Iannello G, Pepe D, Guido D Abstract BACKGROUND: A study...
Related Articles High expression of ghrelin and obestatin prepropeptide in tumor tissues predicted adverse overall survival in gastric carcinoma patients. Medicine (Baltimore). 2020 Jun 26;99(26):e20635 Authors: Wu X, Wu Y, Ye B, Wu F, Wang P Abstract BACKGROUND: Gastric cancer (GC) is the most prevailing digestive tract malignant tumor worldwide with high mortality and recurrence rates. However, its potential molecular mechanism and prognostic...
Related Articles Desmoplastic melanoma: an updated clinical review and the emerging role of genetic markers and immunotherapies. Melanoma Res. 2020 Jun 23;: Authors: Hadfield MJ, Helsing R, Grant-Kels JM Abstract Desmoplastic melanoma (DM) is a rare and histopathologically as well as prognostically distinct subset of melanoma that arises in chronically sun-damaged skin. DM is typically and relatively indolent in nature with most cases not...
Related Articles Lenvatinib plus pembrolizumab in patients with advanced gastric cancer in the first-line or second-line setting (EPOC1706): an open-label, single-arm, phase 2 trial. Lancet Oncol. 2020 Jun 23;: Authors: Kawazoe A, Fukuoka S, Nakamura Y, Kuboki Y, Wakabayashi M, Nomura S, Mikamoto Y, Shima H, Fujishiro N, Higuchi T, Sato A, Kuwata T, Shitara K Abstract BACKGROUND: Pembrolizumab, an anti-PD-1 antibody, results in tumour response...
Related Articles Tumor Growth Dynamic Modeling in Oncology Drug Development and Regulatory Approval: Past, Present, and Future Opportunities. CPT Pharmacometrics Syst Pharmacol. 2020 Jun 26;: Authors: Al-Huniti N, Feng Y, Yu JJ, Lu Z, Nagase M, Zhou D, Sheng J Abstract Model-informed drug development (MIDD) approaches have rapidly advanced in drug development in recent years. Additionally, the Prescription Drug User Fee Act (PDUFA) VI has...
Related Articles Bridging therapy prior to axicabtagene ciloleucel for relapsed/refractory large B-cell lymphoma. Blood Adv. 2020 Jul 14;4(13):2871-2883 Authors: Pinnix CC, Gunther JR, Dabaja BS, Strati P, Fang P, Hawkins MC, Adkins S, Westin J, Ahmed S, Fayad L, Lee HJ, Nair R, Steiner RE, Iyer SP, Rodriguez MA, Wang M, Flowers C, Neelapu SS, Nastoupil LJ Abstract The impact of bridging therapy (BT) administered between leukapheresis and...
Related Articles A medical student scholarly concentrations program: scholarly self-efficacy and impact on future research activities. Med Educ Online. 2020 Dec;25(1):1786210 Authors: DiBiase RM, Beach MC, Carrese JA, Haythornthwaite JA, Wheelan SJ, Atkinson MA, Geller G, Gebo KA, Greene JA, Sozio SM Abstract BACKGROUND: The Scholarly Concentrations program was established at Johns Hopkins University School of Medicine in 2009 with the...
Related Articles Impact of insurance type and timing of Medicaid enrollment on survival among adolescents and young adults with cancer. Pediatr Blood Cancer. 2020 Jun 26;:e28498 Authors: Parsons HM, Maguire FB, Morris CR, Parikh-Patel A, Brunson AM, Wun T, Keegan THM Abstract BACKGROUND: Adolescents and young adults (AYAs) with public or no insurance experience later stage at diagnosis and worse overall survival compared with those with...
Related Articles Tolerability of pemetrexed and oxaliplatin in the treatment of stage III colon cancer during raltitrexed shortage. J Oncol Pharm Pract. 2020 Jun 26;:1078155220934163 Authors: Giani J, Sawyer MB, Chambers C Abstract Colorectal cancer is one of the most common malignancies diagnosed in Canada. Currently, adjuvant colorectal cancer treatment primarily includes chemotherapeutic regimens such as FOLFOX6 (5-fluorouracil, leucovorin,...
Related Articles Defining benchmarks for tolerable risk thresholds in cancer screening: Impact of HPV vaccination on the future of cervical cancer screening. Int J Cancer. 2020 Jun 25;: Authors: Tota JE, Isidean SD, Franco EL Abstract The performance of cervical cancer screening will decline as a function of lower disease prevalence - a consequence of successful human papillomavirus (HPV) vaccination. Replacement of cytology with molecular...
Related Articles Role of cancer stem cell markers ALDH1, BCL11B, BMI-1, and CD44 in the prognosis of advanced HNSCC. Strahlenther Onkol. 2020 Jun 25;: Authors: Jakob M, Sharaf K, Schirmer M, Leu M, Küffer S, Bertlich M, Ihler F, Haubner F, Canis M, Kitz J Abstract PURPOSE: Cancer stem cells (CSCs) are held accountable for the progress of head and neck squamous cell carcinoma (HNSCC). In the presented study, the authors evaluated the prognostic...
Related Articles Clinical value of negative 68Ga-PSMA PET/CT in the management of biochemical recurrent prostate cancer patients. Eur J Nucl Med Mol Imaging. 2020 Jun 26;: Authors: Celli M, De Giorgi U, Caroli P, Di Iorio V, Fantini L, Rossetti V, Foca F, Nicolini S, Giganti M, Paganelli G, Matteucci F Abstract PURPOSE: To evaluate the clinical value of 68Ga-PSMA PET/CT negativity in patients with biochemical recurrent prostate cancer (BCR)....
Related Articles Phonation With a Variably Occluded Facemask: Effects of Task Duration. J Voice. 2020 Jun 22;: Authors: Gillespie AI, Fanucchi A, Gartner-Schmidt J, Belsky M, Awan S Abstract OBJECTIVE: Semioccluded vocal tract (SOVT) exercises are routinely included in many voice therapy programs because they have been shown to improve acoustic, aerodynamic, and patient-reported voice outcomes. One limitation of the traditional SOVT exercise...
Related Articles Resident attitudes and benefits of mock oral board examinations in radiation oncology. BMC Med Educ. 2020 Jun 26;20(1):203 Authors: Peters GW, Decker RH, Park HS, Yu JB, Evans SB Abstract BACKGROUND: Presently, educational programming is not standardized across radiation oncology (RO) training programs. Specifically, there are limited materials through national organizations or structured practice exams for residents preparing...
Related Articles Wheatgrass Juice Administration and Immune Measures during Adjuvant Chemotherapy in Colon Cancer Patients: Preliminary Results. Pharmaceuticals (Basel). 2020 Jun 23;13(6): Authors: Avisar A, Cohen M, Katz R, Shentzer Kutiel T, Aharon A, Bar-Sela G Abstract Adjuvant chemotherapy is recommended in high-risk stage II-III colorectal cancer (CC). We examine the effect of daily wheatgrass juice (WGJ) intake in addition to chemotherapy...
Related Articles Targeted alpha therapy for chronic lymphocytic leukaemia and non-Hodgkin's lymphoma with the anti-CD37 radioimmunoconjugate 212Pb-NNV003. PLoS One. 2020;15(3):e0230526 Authors: Maaland AF, Saidi A, Torgue J, Heyerdahl H, Stallons TAR, Kolstad A, Dahle J Abstract Relapse of chronic lymphocytic leukaemia and non-Hodgkin's lymphoma after standard of care treatment is common and new therapies are needed. The targeted alpha therapy...
Related Articles [Therapeutic strategies in advanced ALK positive non-small cell lung cancer]. Rev Mal Respir. 2019 Dec;36(10):1107-1116 Authors: Tiotiu A, Billon Y, Vaillant P, Menard O, Hofman P, Mascaux C Abstract Anaplastic lymphoma kinase (ALK) rearrangement is a therapeutically targetable oncogenic driver found in 5% of patients with non-small-cell lung cancer (NSCLC). The objective of this paper is to synthesise current knowledge on...
Related Articles Durvalumab for stage III non-small-cell lung cancer patients: clinical evidence and real-world experience. Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466619885530 Authors: Botticella A, Mezquita L, Le Pechoux C, Planchard D Abstract Stage III non-small cell lung cancer (NSCLC) has a dismal prognosis, with only 15-20% of patients alive at 5 years after concomitant chemo-radiotherapy, which represents the standard treatment....
Related Articles The Grief of Parents After the Death of a Young Child. J Clin Psychol Med Settings. 2019 09;26(3):321-338 Authors: Morris S, Fletcher K, Goldstein R Abstract Research demonstrates that severe forms of grief and grief-related pathology exist in the general population. Less attention, however, has been paid to the grief of parents following the death of a young, dependent child. In this review, we summarize a search of Pubmed,...
33 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/06/26PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
33 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/06/26PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
24 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/06/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
24 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/06/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Mark above section as read
Related Articles Sentinel Node Biopsy in Early Breast Cancer Patients with Palpable Axillary Node. Asian Pac J Cancer Prev. 2020 Jun 01;21(6):1631-1636 Authors: Shojaee L, Abedinnegad S, Nafisi N, Naghshvar F, Godazandeh G, Moradi S, Shakeri Astani K, Godazandeh Y Abstract BACKGROUND: Sentinel lymph node biopsy is a reliable method for evaluation of the axillary lymph node status in early stage breast cancer patients with non-palpable lymph...
Related Articles Incidence of pneumonitis/interstitial lung disease induced by HER2-targeting therapy for HER2-positive metastatic breast cancer. Breast Cancer Res Treat. 2020 Jun 26;: Authors: Hackshaw MD, Danysh HE, Singh J, Ritchey ME, Ladner A, Taitt C, Camidge DR, Iwata H, Powell CA Abstract PURPOSE: Anti-human epidermal growth factor receptor 2 (HER2) therapies are associated with interstitial lung disease (ILD), also referred to as pneumonitis....
Related Articles Acetyltanshinone IIA is more potent than lapatinib in inhibiting cell growth and degrading HER2 protein in drug-resistant HER2-positive breast cancer cells. Cancer Lett. 2020 Jun 22;: Authors: Huang B, Yip WK, Wei N, Luo KQ Abstract High expression of human epidermal factor receptor 2 (HER2) is directly related to tumor progression, malignancy and drug resistance in HER2-positive breast cancer (HER2-PBC). The major limitation...
Related Articles Trastuzumab effects depend on HER2 phosphorylation in HER2-negative breast cancer cell lines. PLoS One. 2020;15(6):e0234991 Authors: Burguin A, Furrer D, Ouellette G, Jacob S, Diorio C, Durocher F Abstract The breast cancer (BC) biomarker HER2 (Human Epidermal Receptor 2) is overexpressed in 25% of BC. Only patients with HER2-positive tumors receive HER2-targeting therapies, like trastuzumab (Herceptin). However, some women...
Related Articles Efficacy and Safety of Trastuzumab Emtansine Plus Capecitabine vs Trastuzumab Emtansine Alone in Patients With Previously Treated ERBB2 (HER2)-Positive Metastatic Breast Cancer: A Phase 1 and Randomized Phase 2 Trial. JAMA Oncol. 2020 Jun 25;: Authors: Cortés J, Diéras V, Lorenzen S, Montemurro F, Riera-Knorrenschild J, Thuss-Patience P, Allegrini G, De Laurentiis M, Lohrisch C, Oravcová E, Perez-Garcia JM, Ricci F, Sakaeva D, Serpanchy R, Šufliarský...
Related Articles Characterization of T-DM1-resistant breast cancer cells. Pharmacol Res Perspect. 2020 Aug;8(4):e00617 Authors: Sauveur J, Conilh L, Beaumel S, Chettab K, Jordheim LP, Matera EL, Dumontet C Abstract The development of targeted therapies has drastically improved the outcome of patients with different types of cancer. T-DM1 (trastuzumab-emtansine) is an antibody-drug conjugate used for the treatment of HER2-positive breast cancer...
Related Articles Identification of Aurora Kinase A as a Biomarker for Prognosis in Obesity Patients with Early Breast Cancer. Onco Targets Ther. 2020;13:4971-4985 Authors: Jiang J, Guo Z, Xu J, Sun T, Zheng X Abstract Background: Obesity is associated both with a higher risk of developing breast cancer, particularly in postmenopausal women, and with worse disease outcome for women of all ages. Previous investigation suggested Aurora A kinase...
Related Articles Subtyping of male breast cancer by PAM50 and immunohistochemistry; a pilot study of a consecutive Danish cohort. APMIS. 2020 Jun 24;: Authors: Christensen LG, Lautrup MD, Lyng MB, Möller S, Jylling AMB Abstract Male breast cancer (MBC) is a rare disease that is still to be fully understood. In female breast cancer molecular subtyping by gene expression has proven its significance. In this study we characterize a consecutive...
Related Articles Prognostic value of the Residual Cancer Burden index according to breast cancer subtype: Validation on a cohort of BC patients treated by neoadjuvant chemotherapy. PLoS One. 2020;15(6):e0234191 Authors: Hamy AS, Darrigues L, Laas E, De Croze D, Topciu L, Lam GT, Evrevin C, Rozette S, Laot L, Lerebours F, Pierga JY, Osdoit M, Faron M, Feron JG, Laé M, Reyal F Abstract INTRODUCTION: The Residual Cancer Burden (RCB) quantifies...
Related Articles Phase III study to evaluate patient's preference of subcutaneous versus intravenous trastuzumab in HER2-positive metastatic breast cancer patients: Results from the ChangHER study (GEICAM/2012-07). Eur J Cancer Care (Engl). 2020 Jun 23;:e13253 Authors: Ciruelos EM, Montaño A, Rodríguez CA, González-Flores E, Lluch A, Garrigós L, Quiroga V, Antón A, Malón D, Chacón JI, Velasco M, Gonzalez-Cortijo L, Jolis L, Echarri MJ, Muñoz M, Pascual T, Amigo...
Mark above section as read
Related Articles Neuroendocrine abnormalities associated with untreated first episode patients of major depressive disorder with comorbid obstructive sleep apnea. Psychiatry Res. 2020 Jun 22;291:113248 Authors: Zhang H, Yuan J, Zhang Y, Wei Y, Xu L, Zhou F, Fan X, Kang C, Yang J Abstract There are few studies that explore the relationship of neuroendocrine hormones of the HPA, HPT and HPG axes with major depressive disorder (MDD) with comorbid...
Related Articles IN-HOSPITAL MANAGEMENT OF SLEEP APNEA DURING HEART FAILURE HOSPITALIZATION- A RANDOMIZED CONTROLLED TRIAL. J Card Fail. 2020 Jun 24;: Authors: Khayat RN, Javaheri S, Porter K, Sow A, Holt R, Randerath W, Abraham WT, Jarjoura D Abstract BACKGROUND: Obstructive sleep apnea (OSA) is associated with increased mortality and readmissions in patients with heart failure (HF). The effect of in-hospital diagnosis and treatment of OSA...
Functional Organization of the Insula in Men and Women with Obstructive Sleep Apnea during Valsalva.
Related Articles Functional Organization of the Insula in Men and Women with Obstructive Sleep Apnea during Valsalva. Sleep. 2020 Jun 27;: Authors: Pal A, Ogren JA, Aguila AP, Aysola R, Kumar R, Henderson LA, Harper RM, Macey PM Abstract STUDY OBJECTIVES: Obstructive sleep apnea (OSA) patients show impaired autonomic regulation, perhaps related to functional reorganization of the insula, which in healthy individuals shows sex-specific anterior...
Related Articles Clinical features and risk factors in patients with asthma complicated with obstructive sleep apnea-hypopnea syndrome: a hospital-based study. Sleep Breath. 2020 Jun 27;: Authors: Lin JL, Feng XK, Zhang DM, Sun HY Abstract PURPOSE: The current study was conducted to explore the clinical features and risk factors of patients with asthma complicated by obstructive sleep apnea-hypopnea syndrome (OSAHS). METHODS: Patients...
Related Articles Safety and effectiveness in explantation and re-implantation of hypoglossal nerve stimulation devices. Eur Arch Otorhinolaryngol. 2020 Jun 26;: Authors: Arens P, Penzel T, Fietze I, Blau A, Weller B, Olze H, Dommerich S Abstract PURPOSE: Since 2001, hypoglossal nerve stimulators have been implanted in patients with obstructive sleep apnea around the world, initially in trial situations but more recently also in regular care...
Related Articles Cardiovascular Outcomes Post Percutaneous Coronary Intervention in Patients with Obstructive Sleep Apnea and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. Diabetes Ther. 2020 Jun 26;: Authors: Wang H, Li X, Tang Z, Gong G Abstract INTRODUCTION: Type 2 diabetes mellitus (T2DM) is a major risk factor for the occurrence of cardiovascular diseases. Similar to T2DM, obstructive sleep apnea (OSA) is also known to...
Related Articles Obstructive Sleep Apnea, Other Sleep Characteristics, and Risk of CKD in the Atherosclerosis Risk in Communities Sleep Heart Health Study. J Am Soc Nephrol. 2020 Jun 26;: Authors: Full KM, Jackson CL, Rebholz CM, Matsushita K, Lutsey PL Abstract BACKGROUND: Obstructive sleep apnea may be associated with development of CKD through hypoxia, inflammation, and oxidative stress. Individuals with this sleep disorder are also at increased...
Related Articles Obstructive sleep apnea and pulmonary hypertension: a bidirectional relationship. J Clin Sleep Med. 2020 Jun 26;: Authors: Mesarwi O, Malhotra A PMID: 32588818 [PubMed - as supplied by publisher]
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου