Δευτέρα 29 Ιουνίου 2020


Myeloid diseases in the lung and pleura.
Related Articles Myeloid diseases in the lung and pleura. Semin Diagn Pathol. 2020 Jun 12;: Authors: Khoury JD, Chen W Abstract Myeloid diseases detected as primary or secondary lesions in the lung and pleura are rare. Clinical presentations and radiographic results may vary significantly depending on the nature of the diseases. The most common diseases associated with lung and pleura involvement are myeloid sarcoma/acute myeloid leukemia (AML)...
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Sun Jun 28, 2020 13:22
[Metastatic squamous cell carcinomas of the anal canal: Current management and prospects].
Related Articles [Metastatic squamous cell carcinomas of the anal canal: Current management and prospects]. Bull Cancer. 2020 Jun 23;: Authors: Saint A, Evesque L, François É Abstract Anal canal cancer is a rare disease that accounts for 2.5% of digestive cancers. Squamous cell carcinomas are the most common histological form. Their incidence is in progression, probably due to the increase in Human Papilloma Virus infections. Metastatic forms...
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Sun Jun 28, 2020 13:22
Primary testicular T-lymphoblastic lymphoma in a child: A case report.
Related Articles Primary testicular T-lymphoblastic lymphoma in a child: A case report. Medicine (Baltimore). 2020 Jun 26;99(26):e20861 Authors: Wang Y, Li J, Fang Y Abstract RATIONALE: Primary non-Hodgkin lymphoma (NHL) of the testes is rare, representing about 9% of testicular neoplasms and 1% to 2% of non-Hodgkin lymphomas. PATIENT CONCERNS: A previously healthy 47-month-old boy came to our institution for 3 months unilateral testicular...
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Sat Jun 27, 2020 14:06
Hepatic neuroendocrine neoplasm: imaging patterns.
Related Articles Hepatic neuroendocrine neoplasm: imaging patterns. Radiol Bras. 2020 May-Jun;53(3):195-200 Authors: Houat AP, von Atzingen AC, Velloni FG, de Oliveira RAS, Torres UDS, D'Ippolito G Abstract Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors with distinct morphological and biological manifestations, the liver being the main organ affected by its metastases. However, primary hepatic involvement is quite rare....
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Sat Jun 27, 2020 13:06
Distribution of HPV Genotypes in Patients with a Diagnosis of Anal Cancer in an Italian Region.
Related Articles Distribution of HPV Genotypes in Patients with a Diagnosis of Anal Cancer in an Italian Region. Int J Environ Res Public Health. 2020 Jun 23;17(12): Authors: Muresu N, Sotgiu G, Saderi L, Sechi I, Cossu A, Marras V, Meloni M, Martinelli M, Cocuzza C, Tanda F, Piana A Abstract Objectives: Anal cancer is a rare disease. However, its incidence is increasing in some population groups. Infection caused by Human Papillomavirus (HPV)...
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Sat Jun 27, 2020 13:06
Discovery of Novel Recurrent Mutations and Clinically Meaningful Subgroups in Nodal Marginal Zone Lymphoma.
Related Articles Discovery of Novel Recurrent Mutations and Clinically Meaningful Subgroups in Nodal Marginal Zone Lymphoma. Cancers (Basel). 2020 Jun 23;12(6): Authors: Koh J, Jang I, Choi S, Kim S, Jang I, Ahn HK, Lee C, Paik JH, Kim CW, Lim MS, Kim K, Jeon YK Abstract Nodal marginal zone lymphoma (NMZL) is a rare B-cell neoplasm, the genetic and transcriptomic landscape of which are unclear. Using high-throughput sequencing for whole-exome...
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Sat Jun 27, 2020 13:06
Epidemiology and Risk Factors of Osteosarcoma.
Related Articles Epidemiology and Risk Factors of Osteosarcoma. Cancer Invest. 2020 May;38(5):259-269 Authors: Sadykova LR, Ntekim AI, Muyangwa-Semenova M, Rutland CS, Jeyapalan JN, Blatt N, Rizvanov AA Abstract Osteosarcoma is a rare tumor diagnosed at any age; however younger age is a common risk factor. In addition, multiple factors are believed to contribute to higher rates of osteosarcoma, particularly race and gender. Although diagnosed...
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Sat Jun 27, 2020 13:06
National incidence and initial therapy for thymic carcinoma in Japan: based on analysis of hospital-based cancer registry data, 2009-2015.
Related Articles National incidence and initial therapy for thymic carcinoma in Japan: based on analysis of hospital-based cancer registry data, 2009-2015. Jpn J Clin Oncol. 2020 Apr 07;50(4):434-439 Authors: Koizumi T, Otsuki K, Tanaka Y, Noguchi T, Fukushuima T, Kobayashi T, Ozawa T, Sekiguchi N, Hamanaka K Abstract BACKGROUND: Although thymic carcinoma is a rare epithelial neoplasm that tends to be aggressive and metastasize widely, its...
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Sat Jun 27, 2020 13:06
Malignant peripheral nerve sheath tumor of the bladder A case report.
Related Articles Malignant peripheral nerve sheath tumor of the bladder A case report. Pathologica. 2019 Dec;111(4):365-368 Authors: Petracco G, Patriarca C, Spasciani R, Parafioriti A Abstract Malignant peripheral nerve sheath tumor (MPNST) is an uncommon malignant tumor often associated with Neurofibromatosis type 1 (NF1). Although different soft tissue mesenchymal tumors may arise in the bladder, MPNST is a very rare occurrence. Here, we...
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Sat Jun 27, 2020 13:06
Sirolimus for the treatment of juvenile nasopharyngeal angiofibroma.
Related Articles Sirolimus for the treatment of juvenile nasopharyngeal angiofibroma. Pediatr Blood Cancer. 2020 04;67(4):e28162 Authors: Fernández KS, de Alarcon A, Adams DM, Hammill AM Abstract Juvenile nasopharyngeal angiofibroma (JNA) is a pathologically benign yet locally aggressive and destructive tumor that develops in the choana and nasopharynx. Historical treatment of JNA has included embolization, surgical resection, and radiation....
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Sat Jun 27, 2020 13:06
Histopathological and molecular study for synchronous lung adenocarcinoma staging.
Related Articles Histopathological and molecular study for synchronous lung adenocarcinoma staging. Virchows Arch. 2020 Jun;476(6):835-842 Authors: Donfrancesco E, Yvorel V, Casteillo F, Stachowicz ML, Patoir A, Tiffet O, Péoc'h M, Forest F Abstract The presence of multiple synchronous lung cancer with the same histopathological type for a patient is a common situation and an issue for staging. Pathological criteria exist to distinguish multiple...
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Sat Jun 27, 2020 13:06
Neurofibromatosis-associated malignant peripheral nerve sheath tumors in children have a worse prognosis: A nationwide cohort study.
Related Articles Neurofibromatosis-associated malignant peripheral nerve sheath tumors in children have a worse prognosis: A nationwide cohort study. Pediatr Blood Cancer. 2020 04;67(4):e28138 Authors: Martin E, Coert JH, Flucke UE, Slooff WM, van de Sande MAJ, van Noesel MM, Grünhagen DJ, Wijnen MHWA, Verhoef C Abstract BACKGROUND: Malignant peripheral nerve sheath tumors (MPNST) are rare and aggressive non-rhabdomyoblastic soft-tissue sarcomas...
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Sat Jun 27, 2020 13:06
BCOR-CCNB3 fusion-positive clear cell sarcoma of the kidney.
Related Articles BCOR-CCNB3 fusion-positive clear cell sarcoma of the kidney. Pediatr Blood Cancer. 2020 04;67(4):e28151 Authors: Han H, Bertrand KC, Patel KR, Fisher KE, Roy A, Muscal JA, Venkatramani R Abstract Clear cell sarcoma of the kidney (CCSK) is the second most common malignant pediatric renal tumor. Two of the recurrent somatic alterations reported in CCSK are BCL-6 corepressor (BCOR) internal tandem duplication (ITD) and YWHAE-NUTM2B/E...
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Sat Jun 27, 2020 13:06
Characterisation of tumour microenvironment and immune checkpoints in primary central nervous system diffuse large B cell lymphomas.
Related Articles Characterisation of tumour microenvironment and immune checkpoints in primary central nervous system diffuse large B cell lymphomas. Virchows Arch. 2020 Jun;476(6):891-902 Authors: Alame M, Pirel M, Costes-Martineau V, Bauchet L, Fabbro M, Tourneret A, De Oliveira L, Durand L, Roger P, Gonzalez S, Cacheux V, Rigau V, Szablewski V Abstract Primary central nervous system diffuse large B cell lymphoma (PCNS-DLBCL) is a rare and...
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Sat Jun 27, 2020 13:06
Molecular Evolution of IDH Wild-Type Glioblastomas Treated With Standard of Care Affects Survival and Design of Precision Medicine Trials: A Report From the EORTC 1542 Study.
Related Articles Molecular Evolution of IDH Wild-Type Glioblastomas Treated With Standard of Care Affects Survival and Design of Precision Medicine Trials: A Report From the EORTC 1542 Study. J Clin Oncol. 2020 01 01;38(1):81-99 Authors: Draaisma K, Chatzipli A, Taphoorn M, Kerkhof M, Weyerbrock A, Sanson M, Hoeben A, Lukacova S, Lombardi G, Leenstra S, Hanse M, Fleischeuer R, Watts C, McAbee J, Angelopoulos N, Gorlia T, Golfinopoulos V, Kros JM, Verhaak RGW,...
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Sat Jun 27, 2020 13:06
Results of a Multicenter Phase II Study of Atezolizumab and Bevacizumab for Patients With Metastatic Renal Cell Carcinoma With Variant Histology and/or Sarcomatoid Features.
Related Articles Results of a Multicenter Phase II Study of Atezolizumab and Bevacizumab for Patients With Metastatic Renal Cell Carcinoma With Variant Histology and/or Sarcomatoid Features. J Clin Oncol. 2020 01 01;38(1):63-70 Authors: McGregor BA, McKay RR, Braun DA, Werner L, Gray K, Flaifel A, Signoretti S, Hirsch MS, Steinharter JA, Bakouny Z, Flippot R, Wei XX, Choudhury A, Kilbridge K, Freeman GJ, Van Allen EM, Harshman LC, McDermott DF, Vaishampayan U,...
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Sat Jun 27, 2020 13:06
ACVR1 Function in Health and Disease.
Related Articles ACVR1 Function in Health and Disease. Cells. 2019 10 31;8(11): Authors: Valer JA, Sánchez-de-Diego C, Pimenta-Lopes C, Rosa JL, Ventura F Abstract Activin A receptor type I (ACVR1) encodes for a bone morphogenetic protein type I receptor of the TGFβ receptor superfamily. It is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. Moreover,...
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Sat Jun 27, 2020 13:06
PD-1 Blockade in Advanced Adrenocortical Carcinoma.
Related Articles PD-1 Blockade in Advanced Adrenocortical Carcinoma. J Clin Oncol. 2020 01 01;38(1):71-80 Authors: Raj N, Zheng Y, Kelly V, Katz SS, Chou J, Do RKG, Capanu M, Zamarin D, Saltz LB, Ariyan CE, Untch BR, O'Reilly EM, Gopalan A, Berger MF, Olino K, Segal NH, Reidy-Lagunes DL Abstract PURPOSE: Adrenocortical carcinomas (ACC) are rare and aggressive malignancies with limited treatment options. This study was undertaken to evaluate...
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Sat Jun 27, 2020 13:06
Spinal extradural arachnoid cyst in cervicothoracic junction.
Related Articles Spinal extradural arachnoid cyst in cervicothoracic junction. Spinal Cord Ser Cases. 2019;5:45 Authors: Özdemir M, Pelin Kavak R, Gülgönül N Abstract Introduction: Spinal extradural arachnoid cysts (SEACs) are rare expansive lesions that account for ~1% of all spinal tumors. They develop as the result of arachnoid membrane herniation through a small dural defect and are mostly reported to be located at lower thoracic region...
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Sat Jun 27, 2020 13:06
Germline GPR161 Mutations Predispose to Pediatric Medulloblastoma.
Related Articles Germline GPR161 Mutations Predispose to Pediatric Medulloblastoma. J Clin Oncol. 2020 01 01;38(1):43-50 Authors: Begemann M, Waszak SM, Robinson GW, Jäger N, Sharma T, Knopp C, Kraft F, Moser O, Mynarek M, Guerrini-Rousseau L, Brugieres L, Varlet P, Pietsch T, Bowers DC, Chintagumpala M, Sahm F, Korbel JO, Rutkowski S, Eggermann T, Gajjar A, Northcott P, Elbracht M, Pfister SM, Kontny U, Kurth I Abstract PURPOSE: The identification...
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Sat Jun 27, 2020 13:06
Targeted Therapy in Advanced Melanoma With Rare BRAF Mutations.
Related Articles Targeted Therapy in Advanced Melanoma With Rare BRAF Mutations. J Clin Oncol. 2019 11 20;37(33):3142-3151 Authors: Menzer C, Menzies AM, Carlino MS, Reijers I, Groen EJ, Eigentler T, de Groot JWB, van der Veldt AAM, Johnson DB, Meiss F, Schlaak M, Schilling B, Westgeest HM, Gutzmer R, Pföhler C, Meier F, Zimmer L, Suijkerbuijk KPM, Haalck T, Thoms KM, Herbschleb K, Leichsenring J, Menzer A, Kopp-Schneider A, Long GV, Kefford R, Enk A, Blank CU,...
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Sat Jun 27, 2020 13:06
Prognostic factors and seizure outcome in posterior reversible encephalopathy syndrome (PRES) in children with hematological malignancies and bone marrow failure: A retrospective monocentric study.
Related Articles Prognostic factors and seizure outcome in posterior reversible encephalopathy syndrome (PRES) in children with hematological malignancies and bone marrow failure: A retrospective monocentric study. Seizure. 2019 Nov;72:1-10 Authors: Danhofer P, Tomečková M, Černá D, Zapletalová D, Horák O, Aulická Š, Juříková L, Domanský J, Kovalčíková P, Pavlík T, Štěrba J, Ošlejšková H Abstract PURPOSE: The aim of this study was to evaluate...
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Sat Jun 27, 2020 13:06
[A systemic disease mimicking a rheumatoid arthritis].
Related Articles [A systemic disease mimicking a rheumatoid arthritis]. Rev Med Interne. 2019 Dec;40(12):831-836 Authors: Legrand M, Nouvier M, Paulin L, Deschamps B, Pialat JB, Coury F Abstract INTRODUCTION: Rare systemic diseases such as amyloidosis can mimic inflammatory rheumatic diseases. Because of their poor prognosis, physicians should rule them out at the onset of inflammatory rheumatism. We report a case of AL amyloidosis misdiagnosed...
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Sat Jun 27, 2020 13:06
Nivolumab Combined With Brentuximab Vedotin for Relapsed/Refractory Primary Mediastinal Large B-Cell Lymphoma: Efficacy and Safety From the Phase II CheckMate 436 Study.
Related Articles Nivolumab Combined With Brentuximab Vedotin for Relapsed/Refractory Primary Mediastinal Large B-Cell Lymphoma: Efficacy and Safety From the Phase II CheckMate 436 Study. J Clin Oncol. 2019 11 20;37(33):3081-3089 Authors: Zinzani PL, Santoro A, Gritti G, Brice P, Barr PM, Kuruvilla J, Cunningham D, Kline J, Johnson NA, Mehta-Shah N, Manley T, Francis S, Sharma M, Moskowitz AJ Abstract PURPOSE: Primary mediastinal B-cell lymphoma...
Rare Cancers
Sat Jun 27, 2020 13:06
A rare case of ovarian yolk sac tumour arising from mucinous adenocarcinoma in a 67-year-old woman.
Related Articles A rare case of ovarian yolk sac tumour arising from mucinous adenocarcinoma in a 67-year-old woman. J Obstet Gynaecol. 2020 Jan;40(1):145-146 Authors: Soylemez T, Aydin A, Gunduz N, Ozen F, Kir G PMID: 31339396 [PubMed - indexed for MEDLINE]
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Sat Jun 27, 2020 13:06
Intracranial angiomatoid fibrous histiocytoma with Hodgkin lymphoma.
Related Articles Intracranial angiomatoid fibrous histiocytoma with Hodgkin lymphoma. Med J Malaysia. 2019 06;74(3):234-236 Authors: Gunness VRN, Munoz I, González-López P, Alshafai N, Mikalkova A, Spears J Abstract Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumour of uncertain differentiation and low metastatic potential, which occurs predominantly in children and young adults. It occurs mostly within the extremities, trunk,...
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Sat Jun 27, 2020 13:06
'Pai Syndrome' with anterior alveolar polyp: A variant of a rare clinical entity.
Related Articles 'Pai Syndrome' with anterior alveolar polyp: A variant of a rare clinical entity. Med J Malaysia. 2019 06;74(3):229-230 Authors: Debnath KK, Kanapaty Y, Yong DJ, Chandran S, Bakri A Abstract 'Pai syndrome' (PS) is a rare congenital syndrome. Presented here, a new-born baby-girl who exhibited the characteristic features of having a midline nasal (septal) polyp, an anterior alveolar process polyp, and a pericallosal lipoma associated...
Rare Cancers
Sat Jun 27, 2020 13:06
Malignancies of suprapubic catheter (SPC) tracts in spinal cord injury patients: a case series and review of literature.
Related Articles Malignancies of suprapubic catheter (SPC) tracts in spinal cord injury patients: a case series and review of literature. Spinal Cord Ser Cases. 2019;5:34 Authors: Prattley S, New F, Davies M Abstract Introduction: Spinal cord injury (SCI) patients are at increased risk of bladder cancer. A rare variation of this is a malignancy arising or including the suprapubic catheter (SPC) tract. Case series: We present the first...
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Sat Jun 27, 2020 13:06
Germline variants in oculocutaneous albinism genes and predisposition to familial cutaneous melanoma.
Related Articles Germline variants in oculocutaneous albinism genes and predisposition to familial cutaneous melanoma. Pigment Cell Melanoma Res. 2019 11;32(6):854-863 Authors: Nathan V, Johansson PA, Palmer JM, Howlie M, Hamilton HR, Wadt K, Jönsson G, Brooks KM, Pritchard AL, Hayward NK Abstract Approximately 1%-2% of cutaneous melanoma (CM) is classified as strongly familial. We sought to investigate unexplained CM predisposition in families...
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Sat Jun 27, 2020 13:06
A desmoid tumour (aggressive fibromatosis) in an 80-year-old woman - case report of a rare differential diagnosis in gynaecology.
Related Articles A desmoid tumour (aggressive fibromatosis) in an 80-year-old woman - case report of a rare differential diagnosis in gynaecology. J Obstet Gynaecol. 2020 Jan;40(1):139-140 Authors: Weiss C, Angleitner-Boubenizek L, Motz R, Oppelt P PMID: 31210068 [PubMed - indexed for MEDLINE]
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Sat Jun 27, 2020 13:06
Clinical, Pathology, Genetic, and Molecular Features of Colorectal Tumors in Adolescents and Adults 25 Years or Younger.
Related Articles Clinical, Pathology, Genetic, and Molecular Features of Colorectal Tumors in Adolescents and Adults 25 Years or Younger. Clin Gastroenterol Hepatol. 2020 Jun 22;: Authors: de Voer RM, Diets IJ, van der Post RS, Weren RDA, Kamping EJ, de Bitter TJJ, Elze L, Verhoeven RHA, Vink-Börger E, Eijkelenboom A, Mensenkamp A, Nagtegaal ID, Jongmans MCJ, Ligtenberg MJL Abstract BACKGROUND & AIMS: Colorectal cancers (CRCs) are rare in...
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Fri Jun 26, 2020 15:09
Iris lymphoma - a systematic guide for diagnosis and treatment.
Related Articles Iris lymphoma - a systematic guide for diagnosis and treatment. Surv Ophthalmol. 2020 Jun 22;: Authors: Kakkassery V, Coupland SE, Heindl LM Abstract Iris lymphomas are rare malignant neoplasms arising either as primary tumors in the iris or as secondary tumors involving the iris. We summarize previously published data and make recommendations for work-up strategies for cases of suspected iris lymphoma. Our objective is to provide...
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Fri Jun 26, 2020 15:09
Evaluation of Radiation Sensitivity in Patients with Hyper IgM Syndrome.
Related Articles Evaluation of Radiation Sensitivity in Patients with Hyper IgM Syndrome. Immunol Invest. 2020 Jun 25;:1-17 Authors: Fekrvand S, Mozdarani H, Delavari S, Sohani M, Nazari F, Kiaee F, Bagheri Y, Azizi G, Hassanpour G, Mozdarani S, Abolhassani H, Aghamohammadi A, Yazdani R Abstract BACKGROUND: HIGM syndrome is a rare form of primary immunodeficiencies characterized by normal/increased amounts of serum IgM and decreased serum levels...
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Fri Jun 26, 2020 15:09
Helicobacter pylori-Negative MALT Lymphoma Presenting as a Massive Recurrent Gastrointestinal Hemorrhage.
Related Articles Helicobacter pylori-Negative MALT Lymphoma Presenting as a Massive Recurrent Gastrointestinal Hemorrhage. J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620937166 Authors: Harne PS, Mukherjee S, Achufusi T, Lowe D, Manocha D Abstract Primary gastric lymphoma is rare, representing 5% of all primary gastric neoplasms. The presenting complaints of gastric mucosa-associated lymphoid tissue (MALT) lymphoma are usually...
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Fri Jun 26, 2020 15:09
Genomic profiling of multiple primary cancers including synchronous lung adenocarcinoma and bilateral malignant mesotheliomas: Identification of a novel BAP1 germline variant.
Related Articles Genomic profiling of multiple primary cancers including synchronous lung adenocarcinoma and bilateral malignant mesotheliomas: Identification of a novel BAP1 germline variant. Pathol Int. 2020 Jun 24;: Authors: Shinozaki-Ushiku A, Kohsaka S, Kage H, Oda K, Miyagawa K, Nakajima J, Aburatani H, Mano H, Ushiku T Abstract We report a case with a rare combination of synchronous lung adenocarcinoma and bilateral malignant pleural...
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Fri Jun 26, 2020 13:10
Coronavirus Disease (COVID-19) Outbreak: Hypofractionated Radiotherapy in Soft Tissue Sarcomas as a Valuable Option in the Environment of Limited Medical Resources and Demands for Increased Protection of Patients.
Related Articles Coronavirus Disease (COVID-19) Outbreak: Hypofractionated Radiotherapy in Soft Tissue Sarcomas as a Valuable Option in the Environment of Limited Medical Resources and Demands for Increased Protection of Patients. Front Oncol. 2020;10:993 Authors: Spałek MJ, Rutkowski P PMID: 32582558 [PubMed]
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Fri Jun 26, 2020 13:10
Stereotactic Radiation for Treating Primary and Metastatic Neoplasms of the Spinal Cord.
Related Articles Stereotactic Radiation for Treating Primary and Metastatic Neoplasms of the Spinal Cord. Front Oncol. 2020;10:907 Authors: Liu EK, Silverman JS, Sulman EP Abstract Stereotactic radiation treatment can be used to treat spinal cord neoplasms in patients with either unresectable lesions or residual disease after surgical resection. While treatment guidelines have been suggested for epidural lesions, the utility of stereotactic...
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Fri Jun 26, 2020 13:10
Chemotherapy Curability in Leukemia, Lymphoma, Germ Cell Tumors and Gestational Malignancies: A Reflection of the Unique Physiology of Their Cells of Origin.
Related Articles Chemotherapy Curability in Leukemia, Lymphoma, Germ Cell Tumors and Gestational Malignancies: A Reflection of the Unique Physiology of Their Cells of Origin. Front Genet. 2020;11:426 Authors: Savage P Abstract Cytotoxic DNA damaging chemotherapy brings clinical benefits in the treatment of many metastatic malignancies. However routine curative treatment remains restricted to a small number of malignancies including acute leukemia,...
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Fri Jun 26, 2020 13:10
Chromosomal alterations among age-related haematopoietic clones in Japan.
Related Articles Chromosomal alterations among age-related haematopoietic clones in Japan. Nature. 2020 Jun 24;: Authors: Terao C, Suzuki A, Momozawa Y, Akiyama M, Ishigaki K, Yamamoto K, Matsuda K, Murakami Y, McCarroll SA, Kubo M, Loh PR, Kamatani Y Abstract The extent to which the biology of oncogenesis and ageing are shaped by factors that distinguish human populations is unknown. Haematopoietic clones with acquired mutations become common...
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Fri Jun 26, 2020 13:10
Metachronous Development of Peritoneal Carcinomatosis in a Patient with Autoimmune Pancreatitis.
Related Articles Metachronous Development of Peritoneal Carcinomatosis in a Patient with Autoimmune Pancreatitis. Korean J Gastroenterol. 2020 Jun 25;75(6):356-361 Authors: Lee KW, Chang JH, Kim J, Kim TH, Kim CW, Kim JK, Han SW Abstract Autoimmune pancreatitis (AIP) is a rare and unique type of chronic pancreatitis. The prognosis of AIP, particularly when associated with pancreatic cancer or a related malignancy, is not known. Only a few cases,...
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Fri Jun 26, 2020 13:10
Multifocal Amelanotic Melanoma of the Hard Palate: A Challenging Case.
Related Articles Multifocal Amelanotic Melanoma of the Hard Palate: A Challenging Case. Diagnostics (Basel). 2020 Jun 22;10(6): Authors: Limongelli L, Cascardi E, Capodiferro S, Favia G, Corsalini M, Tempesta A, Maiorano E Abstract Among all melanomas, the mucosal type is very rare and may occur in the sino-nasal mucosa, vagina, anus and the oral cavity. At variance with melanomas of the skin, no risk factors, such as familiarity, UV-exposure...
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Fri Jun 26, 2020 13:10
The effect of age distribution on the prognosis of retroperitoneal neuroblastoma.
Related Articles The effect of age distribution on the prognosis of retroperitoneal neuroblastoma. Medicine (Baltimore). 2020 Jun 05;99(23):e20639 Authors: Liu X, Zhao J, Zhang L, Huang J, Ma Y Abstract Retroperitoneal neuroblastoma is a rare subtype of neuroblastoma and the role of age in its clinical prognosis is still unknown.To describe the age distribution and investigate the association between age and survival outcomes in patients diagnosed...
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Fri Jun 26, 2020 13:10
Palliative bladder radiotherapy: caveats in a changing landscape.
Related Articles Palliative bladder radiotherapy: caveats in a changing landscape. Ann Palliat Med. 2020 05;9(3):1269-1271 Authors: Dirix P, Strijbos M, Van den Mooter T, Vandeursen H PMID: 32279511 [PubMed - indexed for MEDLINE]
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Fri Jun 26, 2020 13:10
Angiomas at the university hospital of Yalgado Ouedraogo in Ouagadougou, Burkina Faso: Epidemiological and clinical profile.
Related Articles Angiomas at the university hospital of Yalgado Ouedraogo in Ouagadougou, Burkina Faso: Epidemiological and clinical profile. Med Sante Trop. 2019 Nov 01;29(4):419-423 Authors: Ouedraogo MS, Korsaga/Some N, Ouedraogo NA, Tapsoba GP, Traoré F, Konkissere GO, Barro/Traoré F, Niamba P, Traoré A Abstract Angiomas are vascular abnormalities that affect less than 1% of the world's population. Data on these disorders in Africa are...
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Fri Jun 26, 2020 13:10
Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial.
Related Articles Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial. Lancet Oncol. 2020 01;21(1):121-133 Authors: Geoerger B, Kang HJ, Yalon-Oren M, Marshall LV, Vezina C, Pappo A, Laetsch TW, Petrilli AS, Ebinger M, Toporski J, Glade-Bender J, Nicholls W, Fox E, DuBois SG, Macy ME, Cohn SL, Pathiraja...
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Fri Jun 26, 2020 13:10
Clinical outcome of prenatally suspected cardiac rhabdomyomas of the fetus.
Related Articles Clinical outcome of prenatally suspected cardiac rhabdomyomas of the fetus. J Perinat Med. 2019 Dec 18;48(1):74-81 Authors: Altmann J, Kiver V, Henrich W, Weichert A Abstract Background The main objective of this retrospective analysis in a large tertiary center was the clinical outcome of prenatally diagnosed cardiac rhabdomyomas as well as the identification of factors influencing fetal prognosis. Methods A total of 45 cases...
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Fri Jun 26, 2020 13:10
Post-operative stereotactic radiosurgery following excision of brain metastases: A systematic review and meta-analysis.
Related Articles Post-operative stereotactic radiosurgery following excision of brain metastases: A systematic review and meta-analysis. Radiother Oncol. 2020 01;142:27-35 Authors: Akanda ZZ, Hong W, Nahavandi S, Haghighi N, Phillips C, Kok DL Abstract BACKGROUND: Following the resection of brain metastases, Stereotactic Radiosurgery (SRS) to the post-operative surgical cavity has increasingly replaced Whole Brain Radiotherapy (WBRT) as the...
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Fri Jun 26, 2020 13:10
Transformation of Viral Light Particles into Near-Infrared Fluorescence Quantum Dot-Labeled Active Tumor-Targeting Nanovectors for Drug Delivery.
Related Articles Transformation of Viral Light Particles into Near-Infrared Fluorescence Quantum Dot-Labeled Active Tumor-Targeting Nanovectors for Drug Delivery. Nano Lett. 2019 10 09;19(10):7035-7042 Authors: Lv C, Zhang TY, Lin Y, Tang M, Zhai CH, Xia HF, Wang J, Zhang ZL, Xie ZX, Chen G, Pang DW Abstract Nanosized oncolytic viral light particles (L-particles), separated from progeny virions, are composed of envelopes and several tegument...
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Fri Jun 26, 2020 13:10
Yolk-Shell Structured Au Nanostar@Metal-Organic Framework for Synergistic Chemo-photothermal Therapy in the Second Near-Infrared Window.
Related Articles Yolk-Shell Structured Au Nanostar@Metal-Organic Framework for Synergistic Chemo-photothermal Therapy in the Second Near-Infrared Window. Nano Lett. 2019 10 09;19(10):6772-6780 Authors: Deng X, Liang S, Cai X, Huang S, Cheng Z, Shi Y, Pang M, Ma P, Lin J Abstract Light-sensitive yolk-shell nanoparticles (YSNs) as remote-controlled and stimuli-responsive theranostic platforms provide an attractive method for synergistic cancer...
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Fri Jun 26, 2020 13:10
Tuberculous abdominal cocoon mimicking peritoneal carcinomatosis.
Related Articles Tuberculous abdominal cocoon mimicking peritoneal carcinomatosis. Antimicrob Resist Infect Control. 2019;8:108 Authors: Meng ZX, Liu Y, Wu R, Shi K, Li T Abstract Background: Tuberculous abdominal cocoon is an uncommon manifestation of abdominal tuberculosis. As a rare clinical entity, it is often encountered unexpectedly in patients with small intestinal obstruction. Here we presented a rare case of tuberculous abdominal...
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Fri Jun 26, 2020 13:10
Cardiac Toxicity From Afatinib in EGFR-Mutated NSCLC: A Rare But Possible Side Effect.
Related Articles Cardiac Toxicity From Afatinib in EGFR-Mutated NSCLC: A Rare But Possible Side Effect. J Thorac Oncol. 2019 07;14(7):e145-e146 Authors: Nuvola G, Dall'Olio FG, Melotti B, Sperandi F, Ardizzoni A PMID: 31235038 [PubMed - indexed for MEDLINE]
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Fri Jun 26, 2020 13:10
Targeted Delivery of IL2 to the Tumor Stroma Potentiates the Action of Immune Checkpoint Inhibitors by Preferential Activation of NK and CD8+ T Cells.
Related Articles Targeted Delivery of IL2 to the Tumor Stroma Potentiates the Action of Immune Checkpoint Inhibitors by Preferential Activation of NK and CD8+ T Cells. Cancer Immunol Res. 2019 04;7(4):572-583 Authors: Hutmacher C, Gonzalo Núñez N, Liuzzi AR, Becher B, Neri D Abstract Recombinant human IL2 is being considered as a combination partner for immune checkpoint inhibitors in cancer therapy, but the product only has a narrow therapeutic...
Rare Cancers
Fri Jun 26, 2020 13:10
Transoral Marsupialization of a Large Dermoid Cyst.
Related Articles Transoral Marsupialization of a Large Dermoid Cyst. J Oral Maxillofac Surg. 2019 Apr;77(4):753-756 Authors: Mumtaz S, Singh M Abstract True dermoid cysts are rare congenital entities with a predilection for periorbital, floor-of-mouth, and submental areas in the head and neck region. They are usually asymptomatic unless they substantially enlarge, causing pain or difficulty in swallowing, breathing, speech, or vision, depending...
Rare Cancers
Fri Jun 26, 2020 13:10
Buccinator and Mandibular Node Metastases in Oral Squamous Cell Carcinoma.
Related Articles Buccinator and Mandibular Node Metastases in Oral Squamous Cell Carcinoma. J Oral Maxillofac Surg. 2019 Apr;77(4):867-873 Authors: Tomioka H, Mochizuki Y, Ohsako T, Hirai H, Shimamoto H, Harada H Abstract PURPOSE: The buccinator and mandibular nodes belong to the facial lymph node group, and metastasis of oral cancer to these nodes is extremely rare. The purpose of this study was to examine particularly rare metastatic cases...
Rare Cancers
Fri Jun 26, 2020 13:10
Scoping review of head and neck neoplasms presenting with obstructive sleep apnoea: the importance of flexible nasendoscopy.
Related Articles Scoping review of head and neck neoplasms presenting with obstructive sleep apnoea: the importance of flexible nasendoscopy. ANZ J Surg. 2020 Jun 24;: Authors: Moore P, Cardemil F, Hayward NJ, Flatman S Abstract BACKGROUND: Obstructive sleep apnoea (OSA) can be caused by neoplasms involving the upper aerodigestive tract. Currently, many of these patients have this diagnosis missed, as most adults diagnosed with OSA do not undergo...
Rare Cancers
Thu Jun 25, 2020 15:06
An anaplastic pleomorphic xanthoastrocytoma with periventricular extension: An autopsy case report and review of the literature.
Related Articles An anaplastic pleomorphic xanthoastrocytoma with periventricular extension: An autopsy case report and review of the literature. Neuropathology. 2020 Jun 23;: Authors: Matsumoto Y, Kobayashi M, Shingu K, Tateishi A, Ohya M, Sano K, Negishi T, Shigeto S, Kobayashi T, Hara Y, Kakizawa Y, Kanno H Abstract Pleomorphic xanthoastrocytomas (PXAs) are rare low-grade astrocytic tumors that typically present as superficial nodular cystic...
Rare Cancers
Thu Jun 25, 2020 13:07
Central nervous system candidiasis beyond neonates: Lessons from a nationwide study.
Related Articles Central nervous system candidiasis beyond neonates: Lessons from a nationwide study. Med Mycol. 2020 Jun 23;: Authors: Chaussade H, Cazals X, Desoubeaux G, Jouvion G, Bougnoux ME, Lefort A, Rivoisy C, Desnos-Ollivier M, Chretien F, Chouaki T, Gruson B, Bernard L, Lortholary O, Lanternier F, French Mycosis study group Abstract Though candidiasis is the most frequent invasive fungal infection, Candida spp. central nervous system...
Rare Cancers
Thu Jun 25, 2020 13:07
A rare case of penile metastases from small cell prostate cancer.
Related Articles A rare case of penile metastases from small cell prostate cancer. Rev Int Androl. 2020 Jun 20;: Authors: Garrido-Abad P, Rodríguez-Cabello MÁ, Vera-Berón R, Platas-Sancho A Abstract We present a case of an 83-year-old-male with painless penile nodules several months after he was diagnosed with pure prostatic small cell carcinoma. Penile doppler ultrasound and magnetic resonance imaging demonstrated solid nodules in both corpora...
Rare Cancers
Thu Jun 25, 2020 13:07
TFE3 Gene Rearrangement in Perivascular Epithelioid Cell Neoplasm (PEComa) of the Genitourinary Tract.
Related Articles TFE3 Gene Rearrangement in Perivascular Epithelioid Cell Neoplasm (PEComa) of the Genitourinary Tract. Clin Genitourin Cancer. 2020 May 15;: Authors: Vannucchi M, Minervini A, Salvi M, Montironi R, Raspollini MR Abstract Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms with unpredictable behavior. They are characterized by epithelioid cells, which stain with melanocytic markers, associated with spindle...
Rare Cancers
Thu Jun 25, 2020 13:07
New generation breast cancer cell lines developed from patient-derived xenografts.
Related Articles New generation breast cancer cell lines developed from patient-derived xenografts. Breast Cancer Res. 2020 Jun 23;22(1):68 Authors: Finlay-Schultz J, Jacobsen BM, Riley D, Paul KV, Turner S, Ferreira-Gonzalez A, Harrell JC, Kabos P, Sartorius CA Abstract BACKGROUND: Breast cancer is a highly heterogeneous disease characterized by multiple histologic and molecular subtypes. While a myriad of breast cancer cell lines have been...
Rare Cancers
Thu Jun 25, 2020 13:07
Ex vivo modelling of drug efficacy in a rare metastatic urachal carcinoma.
Related Articles Ex vivo modelling of drug efficacy in a rare metastatic urachal carcinoma. BMC Cancer. 2020 Jun 23;20(1):590 Authors: Mäkelä R, Arjonen A, Härmä V, Rintanen N, Paasonen L, Paprotka T, Rönsch K, Kuopio T, Kononen J, Rantala JK Abstract BACKGROUND: Ex vivo drug screening refers to the out-of-body assessment of drug efficacy in patient derived vital tumor cells. The purpose of these methods is to enable functional testing of patient...
Rare Cancers
Thu Jun 25, 2020 13:07
VHL-RELATED NEUROENDOCRINE NEOPLASMS AND BEYOND: AN ISRAELI SPECIALIZED CENTER REAL-LIFE REPORT.
Related Articles VHL-RELATED NEUROENDOCRINE NEOPLASMS AND BEYOND: AN ISRAELI SPECIALIZED CENTER REAL-LIFE REPORT. Endocr Pract. 2020 Jun 23;: Authors: Szalat A, Oleinikov K, Nahmias A, Meiner V, Ben-Haim S, Atlan K, Lev-Cohain N, Appelbaum L, Gomori JM, Mazeh H, Khalaileh A, Pe'er J, Lossos A, Shoshan Y, Grozinsky-Glasberg S, Gross DJ Abstract OBJECTIVE: Von Hippel-Lindau (VHL) syndrome is a rare and complex disease. We described in 1996 a three...
Rare Cancers
Thu Jun 25, 2020 13:07
[Progress in diagnosis and treatment of rectal neuroendocrine neoplasms].
Related Articles [Progress in diagnosis and treatment of rectal neuroendocrine neoplasms]. Zhonghua Zhong Liu Za Zhi. 2020 Jun 23;42(6):438-444 Authors: Wu ZJ, Zhou MY, Zheng ZX, Bi JJ, Wang XS, Feng Q Abstract Neuroendocrine neoplasms (NENs) are relatively rare heterogeneous tumors that originate from peptidergic neurons and neuroendocrine cells and have been referred to as "carcinoids" in the past. Although this type of tumor had been previously...
Rare Cancers
Thu Jun 25, 2020 13:07
Oral Manifestations and Complications in Childhood Acute Myeloid Leukemia.
Related Articles Oral Manifestations and Complications in Childhood Acute Myeloid Leukemia. Cancers (Basel). 2020 Jun 19;12(6): Authors: Cammarata-Scalisi F, Girardi K, Strocchio L, Merli P, Bernardin AG, Galeotti A, Magliarditi F, Inserra A, Callea M Abstract Acute myeloid leukemia (AML) is a heterogeneous group of diseases, whose classification is based on lineage-commitment and genetics. Although rare in childhood, it is the most common type...
Rare Cancers
Thu Jun 25, 2020 13:07
Hot Spot TERT Promoter Mutations Are Rare in Sporadic Pancreatic Neuroendocrine Neoplasms and Associated with Telomere Length and Epigenetic Expression Patterns.
Related Articles Hot Spot TERT Promoter Mutations Are Rare in Sporadic Pancreatic Neuroendocrine Neoplasms and Associated with Telomere Length and Epigenetic Expression Patterns. Cancers (Basel). 2020 Jun 19;12(6): Authors: Posch A, Hofer-Zeni S, Klieser E, Primavesi F, Naderlinger E, Brandstetter A, Filipits M, Urbas R, Swiercynski S, Jäger T, Winkelmann P, Kiesslich T, Lu L, Neureiter D, Stättner S, Holzmann K Abstract Cancer cells activate...
Rare Cancers
Thu Jun 25, 2020 13:07
Landscape and function of multiple mutations within individual oncogenes.
Related Articles Landscape and function of multiple mutations within individual oncogenes. Nature. 2020 06;582(7810):95-99 Authors: Saito Y, Koya J, Araki M, Kogure Y, Shingaki S, Tabata M, McClure MB, Yoshifuji K, Matsumoto S, Isaka Y, Tanaka H, Kanai T, Miyano S, Shiraishi Y, Okuno Y, Kataoka K Abstract Sporadic reports have described cancer cases in which multiple driver mutations (MMs) occur in the same oncogene1,2. However, the overall...
Rare Cancers
Thu Jun 25, 2020 13:07
True hermaphroditism with dysgerminoma: A case report.
Related Articles True hermaphroditism with dysgerminoma: A case report. Medicine (Baltimore). 2020 May 29;99(22):e20472 Authors: Chen CQ, Liu Z, Lu YS, Pan M, Huang H Abstract INTRODUCTION: True hermaphroditism is a rare and usually sporadic disorder. It is defined by the presence of both ovarian and testicular tissues together as ovotestis. PATIENT CONCERNS: In this study, we reported a rare true hermaphroditism case with dysgerminoma....
Rare Cancers
Thu Jun 25, 2020 13:07
Clinical characterization of leukemia cutis presentation.
Related Articles Clinical characterization of leukemia cutis presentation. Cutis. 2019 Dec;104(6):326-330;E3 Authors: Haidari W, Strowd LC Abstract Leukemia cutis (LC) is a rare condition that results from infiltration of neoplastic cells into the skin in patients with leukemia, mainly described in case reports or small case series. This study aimed to characterize the clinical presentation of LC and its association with leukemia evolution...
Rare Cancers
Thu Jun 25, 2020 13:07
Hepatoid Adenocarcinoma of Stomach: Emphasis on the Clinical Relationship with Alpha-Fetoprotein-Positive Gastric Cancer.
Related Articles Hepatoid Adenocarcinoma of Stomach: Emphasis on the Clinical Relationship with Alpha-Fetoprotein-Positive Gastric Cancer. Biomed Res Int. 2019;2019:6710428 Authors: Chen EB, Wei YC, Liu HN, Tang C, Liu ML, Peng K, Liu T Abstract Aims: Both hepatoid adenocarcinoma of stomach (HAS) and alpha-fetoprotein-positive gastric cancer (AFPGC) are rare but aggressive subtypes of gastric cancer, but few studies focus on the clinicopathologic...
Rare Cancers
Thu Jun 25, 2020 13:07
Diffuse large B-cell lymphoma of the vagina in pregnancy.
Related Articles Diffuse large B-cell lymphoma of the vagina in pregnancy. BMJ Case Rep. 2020 Jan 02;13(1): Authors: Anusim N, Ionescu F, Afolayan-Oloye O, Gaikazian SS Abstract A 28-year-old primigravida was evaluated for complaints of difficulty urinating and pelvic pain of 6-weeks duration. She denied fever, night sweats, weight loss or fatigue. Pelvic ultrasonography revealed a single fetal pole with cardiac activity and a 7 cm mass in...
Rare Cancers
Thu Jun 25, 2020 13:07
In vitro cytotoxicity of cabazitaxel in adrenocortical carcinoma cell lines and human adrenocortical carcinoma primary cell cultures☆.
Related Articles In vitro cytotoxicity of cabazitaxel in adrenocortical carcinoma cell lines and human adrenocortical carcinoma primary cell cultures☆. Mol Cell Endocrinol. 2019 12 01;498:110585 Authors: Fragni M, Palma Lopez LP, Rossini E, Abate A, Cosentini D, Salvi V, Vezzoli S, Poliani PL, Bosisio D, Hantel C, Tiberio GAM, Grisanti S, Memo M, Terzolo M, Berruti A, Sigala S Abstract Adrenocortical cancer (ACC) is a rare and aggressive malignancy...
Rare Cancers
Thu Jun 25, 2020 13:07
Targeting Interleukin(IL)-30/IL-27p28 signaling in cancer stem-like cells and host environment synergistically inhibits prostate cancer growth and improves survival.
Related Articles Targeting Interleukin(IL)-30/IL-27p28 signaling in cancer stem-like cells and host environment synergistically inhibits prostate cancer growth and improves survival. J Immunother Cancer. 2019 07 31;7(1):201 Authors: Sorrentino C, Yin Z, Ciummo S, Lanuti P, Lu LF, Marchisio M, Bellone M, Di Carlo E Abstract BACKGROUND: Interleukin(IL)-30/IL-27p28 production by Prostate Cancer (PC) Stem-Like Cells (SLCs) has proven, in murine...
Rare Cancers
Thu Jun 25, 2020 13:07
Chondroid lipoma: multimodality imaging in a 9-year-old female.
Related Articles Chondroid lipoma: multimodality imaging in a 9-year-old female. Skeletal Radiol. 2020 Jan;49(1):161-169 Authors: Tannenbaum M, Colucci PG, Baad M, Borczuk AC, Steigman SA, Kovanlikaya A Abstract Chondroid lipomas are rare, benign lipomatous tumors that occur most frequently in adults during the fourth decade of life. While a female predominance was observed in the initial series of 20 cases described in 1993, the subsequent...
Rare Cancers
Thu Jun 25, 2020 13:07
IgG4-related disease: rare presentation as a soft-tissue mass in the thigh of an adolescent.
Related Articles IgG4-related disease: rare presentation as a soft-tissue mass in the thigh of an adolescent. Skeletal Radiol. 2020 Jan;49(1):155-160 Authors: Creze M, Boussebaa S, Lazure T, Briand S, Court C Abstract We report a case of a 16-year-old boy who presented a soft-tissue mass in the anterior compartment of the right thigh discovered by positron emission tomography/computed tomography within the work-up of unexplained prolonged inflammatory...
Rare Cancers
Thu Jun 25, 2020 13:07

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