Δευτέρα 29 Ιουνίου 2020


Comparison of biodegradable synthetic polyurethane foam versus Gelfoam packing in cartilage graft myringoplasty procedures.
Related Articles Comparison of biodegradable synthetic polyurethane foam versus Gelfoam packing in cartilage graft myringoplasty procedures. Auris Nasus Larynx. 2020 Jun 22;: Authors: Lou Z Abstract OBJECTIVE: To compare cartilage graft rates and graft morphologies when biodegradable Synthetic Polyurethane Foam (BSPF) and Gelfoam are used to pack the EAC after cartilage graft myringoplasty. METHODS: Eighty-two patients with chronic...
Larynx
Sat Jun 27, 2020 15:56
Pulsatile tinnitus caused by pneumocephalus after Janneta surgery.
Related Articles Pulsatile tinnitus caused by pneumocephalus after Janneta surgery. Auris Nasus Larynx. 2020 Jun 22;: Authors: Ikeda R, Kikuchi T, Sato S, Oshima H, Kawamura Y, Kusano Y, Kawase T, Katori Y, Kobayashi T Abstract Pulsatile tinnitus of nonvascular origin is rare. We herein present a case of pulsatile tinnitus complicated with Jannetta surgery due to a communication created between the drilled mastoid cells and epidural space. She...
Larynx
Sat Jun 27, 2020 15:56
ENT manifestation in COVID-19 patients.
Related Articles ENT manifestation in COVID-19 patients. Auris Nasus Larynx. 2020 Jun 15;: Authors: El-Anwar MW, Elzayat S, Fouad YA Abstract OBJECTIVE: to detect, analyze and discuss the different ear nose throat (ENT) manifestations those were reported in COVID19 positive patients in the reviewed and published literatures. METHODS: We performed a search in the PubMed databases, Web of Science, LILACS, MEDLINE, SciELO, and Cochrane...
Larynx
Sat Jun 27, 2020 15:56
Differential DNA methylation of vocal and facial anatomy genes in modern humans.
Related Articles Differential DNA methylation of vocal and facial anatomy genes in modern humans. Nat Commun. 2020 03 04;11(1):1189 Authors: Gokhman D, Nissim-Rafinia M, Agranat-Tamir L, Housman G, García-Pérez R, Lizano E, Cheronet O, Mallick S, Nieves-Colón MA, Li H, Alpaslan-Roodenberg S, Novak M, Gu H, Osinski JM, Ferrando-Bernal M, Gelabert P, Lipende I, Mjungu D, Kondova I, Bontrop R, Kullmer O, Weber G, Shahar T, Dvir-Ginzberg M, Faerman M, Quillen EE,...
Larynx
Sat Jun 27, 2020 15:56
MACC1 expression is an indicator of recurrence in early-stage glottic cancer.
Related Articles MACC1 expression is an indicator of recurrence in early-stage glottic cancer. Jpn J Clin Oncol. 2020 Apr 07;50(4):392-398 Authors: Makino T, Orita Y, Gion Y, Tachibana T, Takao S, Marunaka H, Miki K, Akisada N, Akagi Y, Yoshino T, Nishizaki K, Sato Y Abstract BACKGROUND: Metastasis-associated in colon cancer 1 (MACC1) has been reported to be an independent indicator of poor prognoses in some kinds of cancer due to disease metastasis...
Larynx
Sat Jun 27, 2020 15:56
Atypical goblet cell hyperplasia occurs in CPAM 1, 2, and 3, and is a probable precursor lesion for childhood adenocarcinoma.
Related Articles Atypical goblet cell hyperplasia occurs in CPAM 1, 2, and 3, and is a probable precursor lesion for childhood adenocarcinoma. Virchows Arch. 2020 Jun;476(6):843-854 Authors: Fakler F, Aykutlu U, Brcic L, Eidenhammer S, Thueringer A, Kashofer K, Kulka J, Timens W, Popper H Abstract Congenital pulmonary airway malformation (CPAM) is a developmental disorder. Types 1-2-3 are the more common ones. Atypical goblet cell hyperplasia...
Larynx
Sat Jun 27, 2020 15:56
Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures.
Related Articles Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures. Development. 2019 10 23;146(20): Authors: Ruiz García S, Deprez M, Lebrigand K, Cavard A, Paquet A, Arguel MJ, Magnone V, Truchi M, Caballero I, Leroy S, Marquette CH, Marcet B, Barbry P, Zaragosi LE Abstract The upper airway epithelium, which is mainly composed of multiciliated, goblet, club and basal...
Larynx
Sat Jun 27, 2020 15:56
Does interleukin-4 inhibition play a role in dupilumab-associated conjunctivitis?
Related Articles Does interleukin-4 inhibition play a role in dupilumab-associated conjunctivitis? Br J Dermatol. 2020 01;182(1):251 Authors: Waldman RA, DeWane ME, Sloan SB PMID: 31437304 [PubMed - indexed for MEDLINE]
Larynx
Sat Jun 27, 2020 15:56
Adductory Vocal Fold Kinematic Trajectories During Conventional Versus High-Speed Videoendoscopy.
Related Articles Adductory Vocal Fold Kinematic Trajectories During Conventional Versus High-Speed Videoendoscopy. J Speech Lang Hear Res. 2019 06 19;62(6):1685-1706 Authors: Diaz-Cadiz M, McKenna VS, Vojtech JM, Stepp CE Abstract Objective Prephonatory vocal fold angle trajectories may supply useful information about the laryngeal system but were examined in previous studies using sigmoidal curves fit to data collected at 30 frames per second...
Larynx
Sat Jun 27, 2020 15:56
Magnetic resonance imaging-based measurement of internal deformation of vibrating vocal fold models.
Related Articles Magnetic resonance imaging-based measurement of internal deformation of vibrating vocal fold models. J Acoust Soc Am. 2019 02;145(2):989 Authors: Taylor CJ, Tarbox GJ, Bolster BD, Bangerter NK, Thomson SL Abstract A method is presented for tracking the internal deformation of self-oscillating vocal fold models using magnetic resonance imaging (MRI). Silicone models scaled to four times life-size to lower the flow-induced vibration...
Larynx
Sat Jun 27, 2020 15:56
Expression of let-7i and miR-192 is associated with resistance to cisplatin-based chemoradiotherapy in patients with larynx and hypopharynx cancer.
Related Articles Expression of let-7i and miR-192 is associated with resistance to cisplatin-based chemoradiotherapy in patients with larynx and hypopharynx cancer. Oral Oncol. 2020 Jun 22;109:104851 Authors: Poel D, Rustenburg F, Sie D, van Essen HF, Eijk PP, Bloemena E, Elhorst Benites T, van den Berg MC, Vergeer MR, Leemans RC, Buffart TE, Ylstra B, Brakenhoff RH, Verheul HM, Voortman J Abstract OBJECTIVES: The majority of patients with locally...
Larynx
Fri Jun 26, 2020 15:38
Adding Flexible Instrumentation to a Curved Videolaryngoscope: A Novel Tool for Laryngeal Surgery.
Related Articles Adding Flexible Instrumentation to a Curved Videolaryngoscope: A Novel Tool for Laryngeal Surgery. Laryngoscope. 2020 Jun 25;: Authors: Schild LR, Böhm F, Boos M, Kahrs LA, Coburger J, Greve J, Dürselen L, Hoffmann TK, Schuler PJ Abstract OBJECTIVES: Transoral surgery of the larynx with rigid instruments is not always possible. This may result in insufficient therapy or in an increased need for open surgery. For these patients,...
Larynx
Fri Jun 26, 2020 15:38
Alcohol and cancer risk: A systematic review and meta-analysis of prospective Indian studies.
Related Articles Alcohol and cancer risk: A systematic review and meta-analysis of prospective Indian studies. Indian J Public Health. 2020 Apr-Jun;64(2):186-190 Authors: Singhavi HR, Singh A, Bhattacharjee A, Talole S, Dikshit R, Chaturvedi P Abstract Background: Alcohol increases risk of cancer of oral cavity and pharynx, esophagus, colorectal, liver, larynx, and female breast. Objectives: The objective of this study was to determine...
Larynx
Fri Jun 26, 2020 15:38
Pediatric Airway Pathology.
Related Articles Pediatric Airway Pathology. Front Pediatr. 2020;8:246 Authors: Vijayasekaran S Abstract Congenital or acquired disorders of the pediatric airway can affect the upper, lower, or entire airway. There are fundamental differences between the anatomy and physiology of the neonate, pediatric, and adult airways. Infants are not merely small adults in this respect and size, surface area, proportion, resistance, and compliance vary greatly...
Larynx
Fri Jun 26, 2020 15:38
Efficacy of Nivolumab for Head and Neck Cancer Patients with Primary Sites and Histological Subtypes Excluded from the CheckMate-141 Trial.
Related Articles Efficacy of Nivolumab for Head and Neck Cancer Patients with Primary Sites and Histological Subtypes Excluded from the CheckMate-141 Trial. Cancer Manag Res. 2020;12:4161-4168 Authors: Sato Y, Fukuda N, Wang X, Urasaki T, Ohmoto A, Nakano K, Yunokawa M, Ono M, Sato Y, Mitani H, Tomomatsu J, Takahashi S Abstract Background: In the CheckMate-141 trial, nivolumab conferred a survival benefit in patients with recurrent or metastatic...
Larynx
Fri Jun 26, 2020 15:38
Postoperative Concurrent Chemoradiotherapy versus Postoperative Radiotherapy Alone for Larynx Squamous Cell Carcinoma Patients with Lymphovascular Invasion: A Propensity Score Matching Study.
Related Articles Postoperative Concurrent Chemoradiotherapy versus Postoperative Radiotherapy Alone for Larynx Squamous Cell Carcinoma Patients with Lymphovascular Invasion: A Propensity Score Matching Study. Cancer Manag Res. 2020;12:4063-4071 Authors: Yu S, Zhu Y, Shi X, Hu K, Bai C, Diao W, Zhu X, Gao Z, Chen X Abstract Purpose: To date, no guidelines have been proposed for the ideal treatment of postoperative larynx squamous cell carcinoma...
Larynx
Fri Jun 26, 2020 15:38
Risk of internal carotid injury due to peritonsillar abscess drainage.
Related Articles Risk of internal carotid injury due to peritonsillar abscess drainage. Auris Nasus Larynx. 2020 Jun 21;: Authors: Tasli H, Ozen A, Akca ME, Karakoc O Abstract OBJECTIVE: Peritonsillar abscess (PTA) is one of the most commonly seen ear nose and throat (ENT) emergencies. The most catastrophic complication that may occur due to surgical treatment of PTA is injury of internal carotid artery. The aim of this study is to determine...
Larynx
Fri Jun 26, 2020 15:38
Letter to "Medial lingual lymph node metastasis in carcinoma of the tongue".
Related Articles Letter to "Medial lingual lymph node metastasis in carcinoma of the tongue". Auris Nasus Larynx. 2020 Jun 21;: Authors: Deganello A, Rampinelli V, Gualtieri T, Paderno A, Bonomo P, Buglione di Monale E Bastia M PMID: 32580905 [PubMed - as supplied by publisher]
Larynx
Fri Jun 26, 2020 15:38
Effect of Laryngeal Suspension and Upper Esophageal Sphincter Myotomy for Severe Dysphagia Due to Brainstem Disease.
Related Articles Effect of Laryngeal Suspension and Upper Esophageal Sphincter Myotomy for Severe Dysphagia Due to Brainstem Disease. Ann Otol Rhinol Laryngol. 2020 Jul;129(7):689-694 Authors: Shibata S, Kagaya H, Ozeki Y, Saitoh E, Aoyagi Y, Iwata Y, Sakurai K Abstract OBJECTIVES: Surgical procedure is considered in patients with severe dysphagia when conservative treatment fails. This study aimed to evaluate laryngeal suspension (LS) and...
Larynx
Fri Jun 26, 2020 15:38
Surgical treatment of epiglottis collapse in obstructive sleep apnoea syndrome: epiglottis stiffening operation.
Related Articles Surgical treatment of epiglottis collapse in obstructive sleep apnoea syndrome: epiglottis stiffening operation. Acta Otorhinolaryngol Ital. 2019 Dec;39(6):404-408 Authors: Salamanca F, Leone F, Bianchi A, Bellotto RGS, Costantini F, Salvatori P PMID: 31950932 [PubMed - indexed for MEDLINE]
Larynx
Fri Jun 26, 2020 15:38
Percutaneous Endoscopic Gastrostomy versus Nasogastric Tube Feeding: Oropharyngeal Dysphagia Increases Risk for Pneumonia Requiring Hospital Admission.
Related Articles Percutaneous Endoscopic Gastrostomy versus Nasogastric Tube Feeding: Oropharyngeal Dysphagia Increases Risk for Pneumonia Requiring Hospital Admission. Nutrients. 2019 Dec 05;11(12): Authors: Chang WK, Huang HH, Lin HH, Tsai CL Abstract BACKGROUND: Aspiration pneumonia is the most common cause of death in patients with percutaneous endoscopic gastrostomy (PEG) and nasogastric tube (NGT) feeding. This study aimed to compare...
Larynx
Fri Jun 26, 2020 15:38
The Relationship Between Physiological Mechanisms and the Self-Perception of Vocal Effort.
Related Articles The Relationship Between Physiological Mechanisms and the Self-Perception of Vocal Effort. J Speech Lang Hear Res. 2019 04 15;62(4):815-834 Authors: McKenna VS, Diaz-Cadiz ME, Shembel AC, Enos NM, Stepp CE Abstract Purpose This study aimed to examine the relationship between a large set of hypothesized physiological measures of vocal effort and self-ratings of vocal effort. Method Twenty-six healthy adults modulated speech...
Larynx
Fri Jun 26, 2020 15:38
Probe-based confocal laser endomicroscopy in detecting malignant lesions of vocal folds.
Related Articles Probe-based confocal laser endomicroscopy in detecting malignant lesions of vocal folds. Acta Otorhinolaryngol Ital. 2019 Dec;39(6):389-395 Authors: Goncalves M, Aubreville M, Mueller SK, Sievert M, Maier A, Iro H, Bohr C PMID: 30745593 [PubMed - indexed for MEDLINE]
Larynx
Fri Jun 26, 2020 15:38
Comparison of electroglottographic variability index in euphonic and pathological voice.
Related Articles Comparison of electroglottographic variability index in euphonic and pathological voice. Acta Otorhinolaryngol Ital. 2019 Dec;39(6):381-388 Authors: Nacci A, Romeo SO, Cavaliere MD, Macerata A, Bastiani L, Paludetti G, Galli J, Marchese MR, Barillari MR, Barillari U, Berrettini S, Laschi C, Cianchetti M, Manti M, Ursino F, Fattori B PMID: 30745592 [PubMed - indexed for MEDLINE]
Larynx
Fri Jun 26, 2020 15:38
Collagen fibrillar structures in vocal fold scarring and repair using stem cell therapy: a detailed histological, immunohistochemical and atomic force microscopy study.
Related Articles Collagen fibrillar structures in vocal fold scarring and repair using stem cell therapy: a detailed histological, immunohistochemical and atomic force microscopy study. J Microsc. 2019 04;274(1):55-68 Authors: Svistushkin MV, Kotova SL, Shekhter AB, Svistushkin VM, Akovantseva AA, Frolova AA, Fayzullin AL, Starostina SV, Bezrukov EA, Sukhanov RB, Timashev SF, Butnaru DV, Timashev PS Abstract Regenerative medicine opens new...
Larynx
Fri Jun 26, 2020 15:38
Multiple primary malignancies involving lung cancer: a single-center experience.
Related Articles Multiple primary malignancies involving lung cancer: a single-center experience. Tumori. 2020 Jun 24;:300891620933678 Authors: Ventura L, Carbognani P, Gnetti L, Rossi M, Tiseo M, Silini EM, Sverzellati N, Silva M, Succi M, Braggio C, Cattadori S, Bocchialini G, Balestra V, Rusca M, Ampollini L Abstract OBJECTIVE: Currently, unlike earlier years, patients affected by multiple primary malignancies (MPM) are significantly increased,...
Larynx
Thu Jun 25, 2020 15:19
Prospective Anatomical Study To Determine the Site of Insertion of Recurrent Laryngeal Nerve Into the Larynx.
Related Articles Prospective Anatomical Study To Determine the Site of Insertion of Recurrent Laryngeal Nerve Into the Larynx. Clin Otolaryngol. 2020 Jun 23;: Authors: Wu JX, Hanson M, Lohia S, Li H, Wang L, Shaha AR, Ganly I Abstract OBJECTIVES: Determine whether the insertion site of the recurrent laryngeal nerve (RLN) occurs at a predictable distance from the midline trachea, to help guide safe dissection during thyroid surgery. ...
Larynx
Thu Jun 25, 2020 15:19
Clinical practice guidelines for the diagnosis and management of acute otitis media in children-2018 update.
Related Articles Clinical practice guidelines for the diagnosis and management of acute otitis media in children-2018 update. Auris Nasus Larynx. 2020 Jun 20;: Authors: Hayashi T, Kitamura K, Hashimoto S, Hotomi M, Kojima H, Kudo F, Maruyama Y, Sawada S, Taiji H, Takahashi G, Takahashi H, Uno Y, Yano H Abstract OBJECTIVE: "Clinical Practice Guidelines for the Diagnosis and Management of Acute Otitis Media in Children-2018 update (2018 Guidelines)"...
Larynx
Thu Jun 25, 2020 15:19
Epidural blood patch for spontaneous intracranial hypotension (SIH): a report of two cases.
Related Articles Epidural blood patch for spontaneous intracranial hypotension (SIH): a report of two cases. Trop Doct. 2020 Jun 26;:49475520933140 Authors: Arumugam G, Ram S, Naidu P B, Kumaravelu S Abstract One of the latest diagnoses that need to be considered when evaluating patients with persistent headache is spontaneous (postural) intracranial hypotension (SIH). The diagnosis can be clinched by magnetic resonance imaging (MRI) findings...
leak of cerebrospinal fluid
Sat Jun 27, 2020 16:44
Pretruncal Subarachnoid Hemorrhage in a Patient with Cerebrospinal Fluid Leak.
Related Articles Pretruncal Subarachnoid Hemorrhage in a Patient with Cerebrospinal Fluid Leak. Neurocrit Care. 2020 Jun 25;: Authors: Scheitler KM, Nesvick CL, Wijdicks EF PMID: 32588332 [PubMed - as supplied by publisher]
leak of cerebrospinal fluid
Sat Jun 27, 2020 16:44
Shared decision-making for vaccines.
Related Articles Shared decision-making for vaccines. J Am Pharm Assoc (2003). 2020 Jun 22;: Authors: Angelo LB Abstract Shared decision-making is the process by which health care providers and patients work collaboratively to evaluate and select treatment options. In June 2019, this approach was included in the Advisory Committee on Immunization Practices' (ACIP's) updated recommendations for the 9-valent human papillomavirus (9vHPV) and 13-valent...
leak of cerebrospinal fluid
Sat Jun 27, 2020 16:44
Role of the neurotologist in posterior fossa meningioma surgery.
Related Articles Role of the neurotologist in posterior fossa meningioma surgery. Handb Clin Neurol. 2020;170:115-131 Authors: Cheung SW, Russell MS, Pross SE Abstract Posterior fossa meningiomas that impinge on structures of the temporal bone or clivus may be difficult to access for optimal resection that maximizes tumor control and minimizes short- and long-term morbidities. To address this challenge, the contemporary neurosurgery-neurotology...
leak of cerebrospinal fluid
Sat Jun 27, 2020 16:44
Epidemiology, prevalence and risk factors for infections in burn patients: results from a regional burn centre's analysis.
Related Articles Epidemiology, prevalence and risk factors for infections in burn patients: results from a regional burn centre's analysis. J Chemother. 2020 Jun 26;:1-5 Authors: Corcione S, Pensa A, Castiglione A, Lupia T, Bortolaso B, Romeo MR, Stella M, Rosa FG Abstract Burn patients are at high risk of infections due to severe impairment of immunity and loss of skin barrier function. We aimed to describe the epidemiology, incidence and risk...
Mediterranean Society of Chemotherapy,http://goo.gl/xg1MRA
Sat Jun 27, 2020 14:49
Species distribution and antifungal susceptibilities of bloodstream Candida isolates: a nine-years single center survey.
Related Articles Species distribution and antifungal susceptibilities of bloodstream Candida isolates: a nine-years single center survey. J Chemother. 2020 Jun 25;:1-7 Authors: Brescini L, Mazzanti S, Orsetti E, Morroni G, Masucci A, Pocognoli A, Barchiesi F Abstract This study analyzed the epidemiology of bloodstream infections due to Candida spp. in a tertiary referral hospital of Ancona, Italy, and their susceptibility to antifungals. The...
Mediterranean Society of Chemotherapy,http://goo.gl/xg1MRA
Fri Jun 26, 2020 14:29
Neurophotonics Approaches for the Study of Pattern Separation.
Related Articles Neurophotonics Approaches for the Study of Pattern Separation. Front Neural Circuits. 2020;14:26 Authors: Morales C, Morici JF, Miranda M, Gallo FT, Bekinschtein P, Weisstaub NV Abstract Successful memory involves not only remembering over time but also keeping memories distinct. Computational models suggest that pattern separation appears as a highly efficient process to discriminate between overlapping memories. Furthermore,...
Neural-circuits,http://goo.gl/r3fv60
Sat Jun 27, 2020 17:05
Common Principles in Functional Organization of VIP/Calretinin Cell-Driven Disinhibitory Circuits Across Cortical Areas.
Related Articles Common Principles in Functional Organization of VIP/Calretinin Cell-Driven Disinhibitory Circuits Across Cortical Areas. Front Neural Circuits. 2020;14:32 Authors: Guet-McCreight A, Skinner FK, Topolnik L Abstract In the brain, there is a vast diversity of different structures, circuitries, cell types, and cellular genetic expression profiles. While this large diversity can often occlude a clear understanding of how the brain...
Neural-circuits,http://goo.gl/r3fv60
Fri Jun 26, 2020 16:53
Optogenetic Manipulation of Postsynaptic cAMP Using a Novel Transgenic Mouse Line Enables Synaptic Plasticity and Enhances Depolarization Following Tetanic Stimulation in the Hippocampal Dentate Gyrus.
Related Articles Optogenetic Manipulation of Postsynaptic cAMP Using a Novel Transgenic Mouse Line Enables Synaptic Plasticity and Enhances Depolarization Following Tetanic Stimulation in the Hippocampal Dentate Gyrus. Front Neural Circuits. 2020;14:24 Authors: Luyben TT, Rai J, Li H, Georgiou J, Avila A, Zhen M, Collingridge GL, Tominaga T, Okamoto K Abstract cAMP is a positive regulator tightly involved in certain types of synaptic plasticity...
Neural-circuits,http://goo.gl/r3fv60
Fri Jun 26, 2020 16:53
Spatial Updating Depends on Gravity.
Related Articles Spatial Updating Depends on Gravity. Front Neural Circuits. 2020;14:20 Authors: Stahn AC, Riemer M, Wolbers T, Werner A, Brauns K, Besnard S, Denise P, Kühn S, Gunga HC Abstract As we move through an environment the positions of surrounding objects relative to our body constantly change. Maintaining orientation requires spatial updating, the continuous monitoring of self-motion cues to update external locations. This ability...
Neural-circuits,http://goo.gl/r3fv60
Fri Jun 26, 2020 16:53
[Theory and practice of aging upon COVID-19 pandemic.]
Related Articles [Theory and practice of aging upon COVID-19 pandemic.] Adv Gerontol. 2020;33(2):397-408 Authors: Golubev AG, Sidorenko AV Abstract Never before in history, aging was such a significant factor for epidemics as it is now for the current COVID-19 pandemic, which features a drastic shift of mortality towards older ages. Our analysis of data on COVID-19-related mortality in Spain, Italy, and Sweden has shown that, in the range of...
Oncology
Sun Jun 28, 2020 15:30
ATR-CHK1 pathway as a therapeutic target for acute and chronic leukemias.
Related Articles ATR-CHK1 pathway as a therapeutic target for acute and chronic leukemias. Cancer Treat Rev. 2020 May 16;88:102026 Authors: Boudny M, Trbusek M Abstract Progress in cancer therapy changed the outcome of many patients and moved therapy from chemotherapy agents to targeted drugs. Targeted drugs already changed the clinical practice in treatment of leukemias, such as imatinib (BCR/ABL inhibitor) in chronic myeloid leukemia (CML)...
Oncology
Sun Jun 28, 2020 15:30
Metformin: (future) best friend of the radiation oncologist?
Related Articles Metformin: (future) best friend of the radiation oncologist? Radiother Oncol. 2020 Jun 24;: Authors: Chevalier B, Pasquier D, Lartigau EF, Chargari C, Schernberg A, Jannin A, Mirabel X, Vantyghem MC, Escande A Abstract Several molecules are being investigated for their ability to enhance the anti-tumor effect of radiotherapy. The widely prescribed antidiabetic drug metformin has been suggested to possess anti-cancer activity;...
Oncology
Sun Jun 28, 2020 15:30
A survey about the contents and features of oncology clinical pharmacy services and self-evaluations of the oncology pharmacists in China.
Related Articles A survey about the contents and features of oncology clinical pharmacy services and self-evaluations of the oncology pharmacists in China. J Clin Pharm Ther. 2020 Jun 26;: Authors: Wang Y, Dai Y, Yang J, Zhou H, Chen Z, Li G Abstract WHAT IS KNOWN AND OBJECTIVE: In China, with the increased number of oncology patients and use of novel antitumour drugs, the demand of oncology clinical pharmacy services is also growing. However,...
Oncology
Sun Jun 28, 2020 14:02
Prediction of mucositis risk secondary to cancer therapy: a systematic review of current evidence and call to action.
Related Articles Prediction of mucositis risk secondary to cancer therapy: a systematic review of current evidence and call to action. Support Care Cancer. 2020 Jun 26;: Authors: Wardill HR, Sonis ST, Blijlevens NMA, Van Sebille YZA, Ciorba MA, Loeffen EAH, Cheng KKF, Bossi P, Porcello L, Castillo DA, Elad S, Bowen JM, Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) ...
Oncology
Sun Jun 28, 2020 14:02
Clinicopathological characteristics and prognosis analysis of ovarian metastases in colorectal cancer: a single-center experience.
Related Articles Clinicopathological characteristics and prognosis analysis of ovarian metastases in colorectal cancer: a single-center experience. Int J Clin Oncol. 2020 Jun 26;: Authors: Zhou R, Liu Y, Wang Y, Huo X, Zhu J, Zhang T Abstract PURPOSE: This study aimed to improve the management of ovarian metastases (OM) in colorectal cancer (CRC) by evaluating the clinicopathological characteristics, therapeutic strategies, and prognostic factors...
Oncology
Sun Jun 28, 2020 14:02
Nanoparticles in Colorectal Cancer Therapy: Latest In Vivo Assays, Clinical Trials, and Patents.
Related Articles Nanoparticles in Colorectal Cancer Therapy: Latest In Vivo Assays, Clinical Trials, and Patents. AAPS PharmSciTech. 2020 Jun 26;21(5):178 Authors: Cabeza L, Perazzoli G, Mesas C, Jiménez-Luna C, Prados J, Rama AR, Melguizo C Abstract Colorectal cancer (CRC) is the third most common cancer worldwide. Its poor response to current treatment options in advanced stages and the need for efficient diagnosis in early stages call for...
Oncology
Sun Jun 28, 2020 14:02
Histological intratumoral heterogeneity in pretreatment esophageal cancer biopsies predicts survival benefit from neoadjuvant chemotherapy: results from the UK MRC OE02 trial.
Related Articles Histological intratumoral heterogeneity in pretreatment esophageal cancer biopsies predicts survival benefit from neoadjuvant chemotherapy: results from the UK MRC OE02 trial. Dis Esophagus. 2020 Jun 27;: Authors: Davarzani N, Hewitt LC, Hale MD, Melotte V, Nankivell M, Hutchins GGA, Cunningham D, Allum WH, Langley RE, Jolani S, Grabsch HI Abstract Despite the use of multimodal treatment, survival of esophageal cancer (EC) patients...
Oncology
Sun Jun 28, 2020 14:02
Dose-effect relationships of holmium-166 radioembolization in colorectal cancer.
Related Articles Dose-effect relationships of holmium-166 radioembolization in colorectal cancer. J Nucl Med. 2020 Jun 26;: Authors: van Roekel C, Bastiaannet R, Smits MLJ, Bruijnen RC, Braat AJAT, de Jong HWAM, Elias SG, Lam MGEH Abstract INTRODUCTION: Radioembolization is a treatment option for colorectal cancer (CRC) patients with inoperable, chemorefractory hepatic metastases. Personalized treatment requires established dose thresholds....
Oncology
Sun Jun 28, 2020 14:02
Pure Red Cell Aplasia Related to Parvovirus B19 Infection in Simultaneous Pancreas and Kidney Recipient: A Case Report.
Related Articles Pure Red Cell Aplasia Related to Parvovirus B19 Infection in Simultaneous Pancreas and Kidney Recipient: A Case Report. Transplant Proc. 2020 Jun 24;: Authors: Nowacka-Cieciura E, Karakulska-Prystupiuk E, Żuk-Wasek A, Lisik W, Basak GW, Durlik M Abstract A 42-year-old woman received a simultaneous pancreas and kidney transplantation (SPK). Immunosuppression consisted of tacrolimus modified release, prednisone, mycophenolate...
Oncology
Sun Jun 28, 2020 14:02
A structural equation model to assess the pathways of body adiposity and inflammation status on dysmetabolic biomarkers via red cell distribution width and mean corpuscular volume: a cross-sectional study in overweight and obese subjects.
Related Articles A structural equation model to assess the pathways of body adiposity and inflammation status on dysmetabolic biomarkers via red cell distribution width and mean corpuscular volume: a cross-sectional study in overweight and obese subjects. Lipids Health Dis. 2020 Jun 26;19(1):154 Authors: Rondanelli M, Perna S, Alalwan TA, Cazzola R, Gasparri C, Infantino V, Perdoni F, Iannello G, Pepe D, Guido D Abstract BACKGROUND: A study...
Oncology
Sun Jun 28, 2020 14:02
High expression of ghrelin and obestatin prepropeptide in tumor tissues predicted adverse overall survival in gastric carcinoma patients.
Related Articles High expression of ghrelin and obestatin prepropeptide in tumor tissues predicted adverse overall survival in gastric carcinoma patients. Medicine (Baltimore). 2020 Jun 26;99(26):e20635 Authors: Wu X, Wu Y, Ye B, Wu F, Wang P Abstract BACKGROUND: Gastric cancer (GC) is the most prevailing digestive tract malignant tumor worldwide with high mortality and recurrence rates. However, its potential molecular mechanism and prognostic...
Oncology
Sat Jun 27, 2020 14:26
Desmoplastic melanoma: an updated clinical review and the emerging role of genetic markers and immunotherapies.
Related Articles Desmoplastic melanoma: an updated clinical review and the emerging role of genetic markers and immunotherapies. Melanoma Res. 2020 Jun 23;: Authors: Hadfield MJ, Helsing R, Grant-Kels JM Abstract Desmoplastic melanoma (DM) is a rare and histopathologically as well as prognostically distinct subset of melanoma that arises in chronically sun-damaged skin. DM is typically and relatively indolent in nature with most cases not progressing...
Oncology
Sat Jun 27, 2020 14:26
Lenvatinib plus pembrolizumab in patients with advanced gastric cancer in the first-line or second-line setting (EPOC1706): an open-label, single-arm, phase 2 trial.
Related Articles Lenvatinib plus pembrolizumab in patients with advanced gastric cancer in the first-line or second-line setting (EPOC1706): an open-label, single-arm, phase 2 trial. Lancet Oncol. 2020 Jun 23;: Authors: Kawazoe A, Fukuoka S, Nakamura Y, Kuboki Y, Wakabayashi M, Nomura S, Mikamoto Y, Shima H, Fujishiro N, Higuchi T, Sato A, Kuwata T, Shitara K Abstract BACKGROUND: Pembrolizumab, an anti-PD-1 antibody, results in tumour response...
Oncology
Sat Jun 27, 2020 14:26
Tumor Growth Dynamic Modeling in Oncology Drug Development and Regulatory Approval: Past, Present, and Future Opportunities.
Related Articles Tumor Growth Dynamic Modeling in Oncology Drug Development and Regulatory Approval: Past, Present, and Future Opportunities. CPT Pharmacometrics Syst Pharmacol. 2020 Jun 26;: Authors: Al-Huniti N, Feng Y, Yu JJ, Lu Z, Nagase M, Zhou D, Sheng J Abstract Model-informed drug development (MIDD) approaches have rapidly advanced in drug development in recent years. Additionally, the Prescription Drug User Fee Act (PDUFA) VI has specific...
Oncology
Sat Jun 27, 2020 14:26
Bridging therapy prior to axicabtagene ciloleucel for relapsed/refractory large B-cell lymphoma.
Related Articles Bridging therapy prior to axicabtagene ciloleucel for relapsed/refractory large B-cell lymphoma. Blood Adv. 2020 Jul 14;4(13):2871-2883 Authors: Pinnix CC, Gunther JR, Dabaja BS, Strati P, Fang P, Hawkins MC, Adkins S, Westin J, Ahmed S, Fayad L, Lee HJ, Nair R, Steiner RE, Iyer SP, Rodriguez MA, Wang M, Flowers C, Neelapu SS, Nastoupil LJ Abstract The impact of bridging therapy (BT) administered between leukapheresis and chimeric...
Oncology
Sat Jun 27, 2020 14:26
A medical student scholarly concentrations program: scholarly self-efficacy and impact on future research activities.
Related Articles A medical student scholarly concentrations program: scholarly self-efficacy and impact on future research activities. Med Educ Online. 2020 Dec;25(1):1786210 Authors: DiBiase RM, Beach MC, Carrese JA, Haythornthwaite JA, Wheelan SJ, Atkinson MA, Geller G, Gebo KA, Greene JA, Sozio SM Abstract BACKGROUND: The Scholarly Concentrations program was established at Johns Hopkins University School of Medicine in 2009 with the aim of...
Oncology
Sat Jun 27, 2020 14:26
Impact of insurance type and timing of Medicaid enrollment on survival among adolescents and young adults with cancer.
Related Articles Impact of insurance type and timing of Medicaid enrollment on survival among adolescents and young adults with cancer. Pediatr Blood Cancer. 2020 Jun 26;:e28498 Authors: Parsons HM, Maguire FB, Morris CR, Parikh-Patel A, Brunson AM, Wun T, Keegan THM Abstract BACKGROUND: Adolescents and young adults (AYAs) with public or no insurance experience later stage at diagnosis and worse overall survival compared with those with private...
Oncology
Sat Jun 27, 2020 14:26
Tolerability of pemetrexed and oxaliplatin in the treatment of stage III colon cancer during raltitrexed shortage.
Related Articles Tolerability of pemetrexed and oxaliplatin in the treatment of stage III colon cancer during raltitrexed shortage. J Oncol Pharm Pract. 2020 Jun 26;:1078155220934163 Authors: Giani J, Sawyer MB, Chambers C Abstract Colorectal cancer is one of the most common malignancies diagnosed in Canada. Currently, adjuvant colorectal cancer treatment primarily includes chemotherapeutic regimens such as FOLFOX6 (5-fluorouracil, leucovorin,...
Oncology
Sat Jun 27, 2020 14:26
Defining benchmarks for tolerable risk thresholds in cancer screening: Impact of HPV vaccination on the future of cervical cancer screening.
Related Articles Defining benchmarks for tolerable risk thresholds in cancer screening: Impact of HPV vaccination on the future of cervical cancer screening. Int J Cancer. 2020 Jun 25;: Authors: Tota JE, Isidean SD, Franco EL Abstract The performance of cervical cancer screening will decline as a function of lower disease prevalence - a consequence of successful human papillomavirus (HPV) vaccination. Replacement of cytology with molecular HPV...
Oncology
Sat Jun 27, 2020 14:26
Role of cancer stem cell markers ALDH1, BCL11B, BMI-1, and CD44 in the prognosis of advanced HNSCC.
Related Articles Role of cancer stem cell markers ALDH1, BCL11B, BMI-1, and CD44 in the prognosis of advanced HNSCC. Strahlenther Onkol. 2020 Jun 25;: Authors: Jakob M, Sharaf K, Schirmer M, Leu M, Küffer S, Bertlich M, Ihler F, Haubner F, Canis M, Kitz J Abstract PURPOSE: Cancer stem cells (CSCs) are held accountable for the progress of head and neck squamous cell carcinoma (HNSCC). In the presented study, the authors evaluated the prognostic...
Oncology
Sat Jun 27, 2020 14:26
Clinical value of negative 68Ga-PSMA PET/CT in the management of biochemical recurrent prostate cancer patients.
Related Articles Clinical value of negative 68Ga-PSMA PET/CT in the management of biochemical recurrent prostate cancer patients. Eur J Nucl Med Mol Imaging. 2020 Jun 26;: Authors: Celli M, De Giorgi U, Caroli P, Di Iorio V, Fantini L, Rossetti V, Foca F, Nicolini S, Giganti M, Paganelli G, Matteucci F Abstract PURPOSE: To evaluate the clinical value of 68Ga-PSMA PET/CT negativity in patients with biochemical recurrent prostate cancer (BCR)....
Oncology
Sat Jun 27, 2020 14:26
Phonation With a Variably Occluded Facemask: Effects of Task Duration.
Related Articles Phonation With a Variably Occluded Facemask: Effects of Task Duration. J Voice. 2020 Jun 22;: Authors: Gillespie AI, Fanucchi A, Gartner-Schmidt J, Belsky M, Awan S Abstract OBJECTIVE: Semioccluded vocal tract (SOVT) exercises are routinely included in many voice therapy programs because they have been shown to improve acoustic, aerodynamic, and patient-reported voice outcomes. One limitation of the traditional SOVT exercise...
Oncology
Sat Jun 27, 2020 14:26
Resident attitudes and benefits of mock oral board examinations in radiation oncology.
Related Articles Resident attitudes and benefits of mock oral board examinations in radiation oncology. BMC Med Educ. 2020 Jun 26;20(1):203 Authors: Peters GW, Decker RH, Park HS, Yu JB, Evans SB Abstract BACKGROUND: Presently, educational programming is not standardized across radiation oncology (RO) training programs. Specifically, there are limited materials through national organizations or structured practice exams for residents preparing...
Oncology
Sat Jun 27, 2020 14:26
Wheatgrass Juice Administration and Immune Measures during Adjuvant Chemotherapy in Colon Cancer Patients: Preliminary Results.
Related Articles Wheatgrass Juice Administration and Immune Measures during Adjuvant Chemotherapy in Colon Cancer Patients: Preliminary Results. Pharmaceuticals (Basel). 2020 Jun 23;13(6): Authors: Avisar A, Cohen M, Katz R, Shentzer Kutiel T, Aharon A, Bar-Sela G Abstract Adjuvant chemotherapy is recommended in high-risk stage II-III colorectal cancer (CC). We examine the effect of daily wheatgrass juice (WGJ) intake in addition to chemotherapy...
Oncology
Sat Jun 27, 2020 14:26
[Therapeutic strategies in advanced ALK positive non-small cell lung cancer].
Related Articles [Therapeutic strategies in advanced ALK positive non-small cell lung cancer]. Rev Mal Respir. 2019 Dec;36(10):1107-1116 Authors: Tiotiu A, Billon Y, Vaillant P, Menard O, Hofman P, Mascaux C Abstract Anaplastic lymphoma kinase (ALK) rearrangement is a therapeutically targetable oncogenic driver found in 5% of patients with non-small-cell lung cancer (NSCLC). The objective of this paper is to synthesise current knowledge on...
Oncology
Sat Jun 27, 2020 14:26
Expression of platelet-derived growth factor receptor-α/ß, vascular endothelial growth factor receptor-2, c-Abl, and c-Kit in canine granulomatous meningoencephalitis and necrotizing encephalitis.
Related Articles Expression of platelet-derived growth factor receptor-α/ß, vascular endothelial growth factor receptor-2, c-Abl, and c-Kit in canine granulomatous meningoencephalitis and necrotizing encephalitis. Vet Med Sci. 2020 Jun 25;: Authors: Song JH, Yu DH, Hwang TS, Seung BJ, Sur JH, Kim YJ, Jung DI Abstract BACKGROUND: Given the active research on targeted therapy using tyrosine kinase (TK) inhibitors (TKIs) in the field of oncology,...
Oncology
Fri Jun 26, 2020 14:57
Novel methodology to investigate the impact of radiation dose to heart sub-structures on overall survival.
Related Articles Novel methodology to investigate the impact of radiation dose to heart sub-structures on overall survival. Int J Radiat Oncol Biol Phys. 2020 Jun 22;: Authors: McWilliam A, Khalifa J, Vasquez Osorio E, Banfill K, Abravan A, Faivre-Finn C, van Herk M Abstract INTRODUCTION: For lung cancer patients treated with radiotherapy, dose to the heart is associated with excess mortality. However, it is often not feasible to spare the whole...
Oncology
Fri Jun 26, 2020 14:57
Automatic diagnosis of melanoma using hyperspectral data and GoogLeNet.
Related Articles Automatic diagnosis of melanoma using hyperspectral data and GoogLeNet. Skin Res Technol. 2020 Jun 25;: Authors: Hirano G, Nemoto M, Kimura Y, Kiyohara Y, Koga H, Yamazaki N, Christensen G, Ingvar C, Nielsen K, Nakamura A, Sota T, Nagaoka T Abstract BACKGROUND: Melanoma is a type of superficial tumor. As advanced melanoma has a poor prognosis, early detection and therapy are essential to reduce melanoma-related deaths. To that...
Oncology
Fri Jun 26, 2020 14:57
The activity of chemotherapy in inflammatory myofibroblastic tumour (IMT): a multicentre, European retrospective case series analysis.
Related Articles The activity of chemotherapy in inflammatory myofibroblastic tumour (IMT): a multicentre, European retrospective case series analysis. Oncologist. 2020 Jun 25;: Authors: Baldi GG, Brahmi M, Lo Vullo S, Cojocaru E, Mir O, Casanova M, Vincenzi B, De Pas T, Grignani G, Pantaleo MA, Blay JY, Jones RL, Le Cesne A, Frezza AM, Gronchi A, Collini P, Dei Tos AP, Morosi C, Mariani L, Casali PG, Stacchiotti S Abstract BACKGROUND: To report...
Oncology
Fri Jun 26, 2020 14:57
Cancer management challenge in a developing country in COVID-19 pandemic: reflection of a group of Moroccan oncologists.
Related Articles Cancer management challenge in a developing country in COVID-19 pandemic: reflection of a group of Moroccan oncologists. Future Oncol. 2020 Jun 25;: Authors: Mrabti H, Berrada N, Raiss G, Ettahri H, Abahssain H, Bourhafour M, Sahraoui S, Errihani H Abstract Management of cancer patients during the COVID-19 pandemic is a worldwide challenge - in particular in developing countries where the risk of saturation of health facilities...
Oncology
Fri Jun 26, 2020 14:57
Fertility under uncertainty: exploring differences in fertility-related concerns and psychosocial aspects between breast cancer survivors and non-cancer infertile women.
Related Articles Fertility under uncertainty: exploring differences in fertility-related concerns and psychosocial aspects between breast cancer survivors and non-cancer infertile women. Breast Cancer. 2020 Jun 24;: Authors: Bártolo A, Neves M, Carvalho B, Reis S, Valério E, Santos IM, Monteiro S Abstract BACKGROUND: The threat to fertility due to anticancer treatments can be distressing to women who wish to complete their family. The current...
Oncology
Fri Jun 26, 2020 13:28
Cardiac Imaging in Oncology Patients in Europe: a Model for Advancement of CV Safety and Development of Comprehensive CV Care.
Related Articles Cardiac Imaging in Oncology Patients in Europe: a Model for Advancement of CV Safety and Development of Comprehensive CV Care. J Cardiovasc Transl Res. 2020 Jun 25;: Authors: López-Fernández T Abstract Cancer therapy-related cardiovascular events are widely recognized as a global problem, and cardio-oncology has been proposed as a new approach to coordinate preventive strategies in oncologic patients. Cardiac imaging plays a...
Oncology
Fri Jun 26, 2020 13:28
Whole milk consumption is associated with lower risk of coronary artery calcification progression: evidences from the Multi-Ethnic Study of Atherosclerosis.
Related Articles Whole milk consumption is associated with lower risk of coronary artery calcification progression: evidences from the Multi-Ethnic Study of Atherosclerosis. Eur J Nutr. 2020 Jun 24;: Authors: Ghosh S, He W, Gao J, Luo D, Wang J, Chen J, Huang H Abstract PURPOSE: Coronary artery calcification (CAC) progression is a strong predictor of cardiovascular disease (CVD) morbidity and mortality. However, the association between whole...
Oncology
Fri Jun 26, 2020 13:28
Associations between voxel-level accumulated dose and rectal toxicity in prostate radiotherapy.
Related Articles Associations between voxel-level accumulated dose and rectal toxicity in prostate radiotherapy. Phys Imaging Radiat Oncol. 2020 Apr;14:87-94 Authors: Shelley LEA, Sutcliffe MPF, Thomas SJ, Noble DJ, Romanchikova M, Harrison K, Bates AM, Burnet NG, Jena R Abstract Background and Purpose: Associations between dose and rectal toxicity in prostate radiotherapy are generally poorly understood. Evaluating spatial dose distributions...
Oncology
Fri Jun 26, 2020 13:28
Disease Activity-Associated Alteration of mRNA m5 C Methylation in CD4+ T Cells of Systemic Lupus Erythematosus.
Related Articles Disease Activity-Associated Alteration of mRNA m5 C Methylation in CD4+ T Cells of Systemic Lupus Erythematosus. Front Cell Dev Biol. 2020;8:430 Authors: Guo G, Wang H, Shi X, Ye L, Yan K, Chen Z, Zhang H, Jin Z, Xue X Abstract Epigenetic processes including RNA methylation, post-translational modifications, and non-coding RNA expression have been associated with the heritable risks of systemic lupus erythematosus (SLE). In...
Oncology
Fri Jun 26, 2020 13:28
The Immunomodulatory Signature of Extracellular Vesicles From Cardiosphere-Derived Cells: A Proteomic and miRNA Profiling.
Related Articles The Immunomodulatory Signature of Extracellular Vesicles From Cardiosphere-Derived Cells: A Proteomic and miRNA Profiling. Front Cell Dev Biol. 2020;8:321 Authors: López E, Marinaro F, de Pedro MLÁ, Sánchez-Margallo FM, Gómez-Serrano M, Ponath V, Pogge von Strandmann E, Jorge I, Vázquez J, Fernández-Pereira LM, Crisóstomo V, Álvarez V, Casado JG Abstract Experimental data demonstrated that the regenerative potential and immunomodulatory...
Oncology
Fri Jun 26, 2020 13:28
Current Strategies and Future Directions to Achieve Deep Molecular Response and Treatment-Free Remission in Chronic Myeloid Leukemia.
Related Articles Current Strategies and Future Directions to Achieve Deep Molecular Response and Treatment-Free Remission in Chronic Myeloid Leukemia. Front Oncol. 2020;10:883 Authors: Annunziata M, Bonifacio M, Breccia M, Castagnetti F, Gozzini A, Iurlo A, Pregno P, Stagno F, Specchia G Abstract The treatment of chronic myeloid leukemia (CML) has been radically changed by the approval of tyrosine kinase inhibitors (TKIs), which target BCR-ABL1...
Oncology
Fri Jun 26, 2020 13:28
Radiogenomics Based on PET Imaging.
Related Articles Radiogenomics Based on PET Imaging. Nucl Med Mol Imaging. 2020 Jun;54(3):128-138 Authors: Park YJ, Shin MH, Moon SH Abstract Radiogenomics or imaging genomics is a novel omics strategy of associating imaging data with genetic information, which has the potential to advance personalized medicine. Imaging features extracted from PET or PET/CT enable assessment of in vivo functional and physiological activity and provide comprehensive...
Oncology
Fri Jun 26, 2020 13:28
In vivo Imaging Technologies to Monitor the Immune System.
Related Articles In vivo Imaging Technologies to Monitor the Immune System. Front Immunol. 2020;11:1067 Authors: McCarthy CE, White JM, Viola NT, Gibson HM Abstract The past two decades have brought impressive advancements in immune modulation, particularly with the advent of both cancer immunotherapy and biologic therapeutics for inflammatory conditions. However, the dynamic nature of the immune response often complicates the assessment of...
Oncology
Fri Jun 26, 2020 13:28
High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot.
Related Articles High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot. J Immunother Cancer. 2020 Jun;8(1): Authors: Keam SP, Halse H, Nguyen T, Wang M, Van Kooten Losio N, Mitchell C, Caramia F, Byrne DJ, Haupt S, Ryland G, Darcy PK, Sandhu S, Blombery P, Haupt Y, Williams SG, Neeson PJ Abstract BACKGROUND: Prostate cancer (PCa) has a profoundly immunosuppressive microenvironment and is commonly immune excluded...
Oncology
Fri Jun 26, 2020 13:28
Sequential ctDNA whole-exome sequencing in advanced lung adenocarcinoma with initial durable tumor response on immune checkpoint inhibitor and late progression.
Related Articles Sequential ctDNA whole-exome sequencing in advanced lung adenocarcinoma with initial durable tumor response on immune checkpoint inhibitor and late progression. J Immunother Cancer. 2020 Jun;8(1): Authors: Giroux Leprieur E, Hélias-Rodzewicz Z, Takam Kamga P, Costantini A, Julie C, Corjon A, Dumenil C, Dumoulin J, Giraud V, Labrune S, Garinet S, Chinet T, Emile JF Abstract BACKGROUND: Despite prolonged tumor response to immune...
Oncology
Fri Jun 26, 2020 13:28
Proteomics of Galápagos marine iguanas links function of femoral gland proteins to the immune system.
Related Articles Proteomics of Galápagos marine iguanas links function of femoral gland proteins to the immune system. Mol Cell Proteomics. 2020 Jun 24;: Authors: Tellkamp F, Lang F, Ibáñez Ricoma A, Abraham L, Quezada G, Günther S, Looso M, Tann FJ, Müller D, Cemic F, Hemberger J, Steinfartz S, Krüger M Abstract Communication between individuals via molecules, termed chemosignaling, is widespread among animal and plant species. However, we...
Oncology
Fri Jun 26, 2020 13:28
A fast, simple, and cost-effective method of expanding patient-derived xenograft mouse models of pancreatic ductal adenocarcinoma.
Related Articles A fast, simple, and cost-effective method of expanding patient-derived xenograft mouse models of pancreatic ductal adenocarcinoma. J Transl Med. 2020 Jun 24;18(1):255 Authors: Liu Z, Ahn MH, Kurokawa T, Ly A, Zhang G, Wang F, Yamada T, Sadagopan A, Cheng J, Ferrone CR, Liss AS, Honselmann KC, Wojtkiewicz GR, Ferrone S, Wang X Abstract BACKGROUND: Patient-derived xenograft (PDX) mouse models of cancer have been recognized as...
Oncology
Fri Jun 26, 2020 13:28
GUIP1: a R package for dose escalation strategies in phase I cancer clinical trials.
Related Articles GUIP1: a R package for dose escalation strategies in phase I cancer clinical trials. BMC Med Inform Decis Mak. 2020 Jun 24;20(1):134 Authors: Dinart D, Fraisse J, Tosi D, Mauguen A, Touraine C, Gourgou S, Le Deley MC, Bellera C, Mollevi C Abstract BACKGROUND: The main objective of phase I cancer clinical trials is to identify the maximum tolerated dose, usually defined as the highest dose associated with an acceptable level...
Oncology
Fri Jun 26, 2020 13:28
Investigative therapy for advanced esophageal cancer using the option for combined immunotherapy and chemotherapy.
Related Articles Investigative therapy for advanced esophageal cancer using the option for combined immunotherapy and chemotherapy. Immunotherapy. 2020 Jun 25;: Authors: Wang H, Xuan TT, Chen Y, Yu H, Gu TT, Zhou G, Liang L, Cao FL Abstract Aim: Advanced esophageal cancer has limited therapeutic options and a poor outcome. The efficacy of immunotherapy, as the first-line treatment of advanced esophageal cancer, is uncertain. Results: A stage...
Oncology
Fri Jun 26, 2020 13:28
Infigratinib in patients with advanced cholangiocarcinoma with FGFR2 gene fusions/translocations: the PROOF 301 trial.
Related Articles Infigratinib in patients with advanced cholangiocarcinoma with FGFR2 gene fusions/translocations: the PROOF 301 trial. Future Oncol. 2020 Jun 25;: Authors: Makawita S, K Abou-Alfa G, Roychowdhury S, Sadeghi S, Borbath I, Goyal L, Cohn A, Lamarca A, Oh DY, Macarulla T, T Shroff R, Howland M, Li A, Cho T, Pande A, Javle M Abstract Cholangiocarcinoma is an aggressive malignancy with poor overall survival. Approximately 15% of intrahepatic...
Oncology
Fri Jun 26, 2020 13:28
New Frontiers in Prostate Cancer Treatment: Are We Ready for Drug Combinations with Novel Agents?
Related Articles New Frontiers in Prostate Cancer Treatment: Are We Ready for Drug Combinations with Novel Agents? Cells. 2020 Jun 22;9(6): Authors: Aurilio G, Cimadamore A, Santoni M, Nolè F, Scarpelli M, Massari F, Lopez-Beltran A, Cheng L, Montironi R Abstract Medical treatment for metastatic castration-resistant prostate cancer (mCRPC) patients has progressively been evolving from a nonspecific clinical approach to genomics-oriented therapies....
Oncology
Fri Jun 26, 2020 13:28
Exploiting Cancer's Tactics to Make Cancer a Manageable Chronic Disease.
Related Articles Exploiting Cancer's Tactics to Make Cancer a Manageable Chronic Disease. Cancers (Basel). 2020 Jun 22;12(6): Authors: Afrasiabi K, Linskey ME, Zhou YH Abstract The history of modern oncology started around eighty years ago with the introduction of cytotoxic agents such as nitrogen mustard into the clinic, followed by multi-agent chemotherapy protocols. Early success in radiation therapy in Hodgkin lymphoma gave birth to the...
Oncology
Fri Jun 26, 2020 13:28
Results from Phase I Clinical Trial with Intraspinal Injection of Neural Stem Cells in Amyotrophic Lateral Sclerosis: A Long-Term Outcome.
Related Articles Results from Phase I Clinical Trial with Intraspinal Injection of Neural Stem Cells in Amyotrophic Lateral Sclerosis: A Long-Term Outcome. Stem Cells Transl Med. 2019 09;8(9):887-897 Authors: Mazzini L, Gelati M, Profico DC, Sorarù G, Ferrari D, Copetti M, Muzi G, Ricciolini C, Carletti S, Giorgi C, Spera C, Frondizi D, Masiero S, Stecco A, Cisari C, Bersano E, De Marchi F, Sarnelli MF, Querin G, Cantello R, Petruzzelli F, Maglione A, Zalfa...
Oncology
Fri Jun 26, 2020 13:28
Loss of efficacy of subsequent non-surgical therapy after primary treatment failure in pediatric low-grade glioma patients - report from the German SIOP-LGG 2004 cohort.
Related Articles Loss of efficacy of subsequent non-surgical therapy after primary treatment failure in pediatric low-grade glioma patients - report from the German SIOP-LGG 2004 cohort. Int J Cancer. 2020 Jun 24;: Authors: Kandels D, Pietsch T, Bison B, Warmuth-Metz M, Thomale UW, Kortmann RD, Timmermann B, Driever PH, Witt O, Schmidt R, Gnekow AK Abstract First-line treatment of pediatric low-grade glioma using surgery, radio- or chemotherapy...
Oncology
Thu Jun 25, 2020 15:22
Enzalutamide plus androgen-deprivation therapy in hormone-sensitive prostate cancer: new perspectives from a current Phase III clinical trial.
Related Articles Enzalutamide plus androgen-deprivation therapy in hormone-sensitive prostate cancer: new perspectives from a current Phase III clinical trial. Future Oncol. 2020 Jun 24;: Authors: Norz V, Lawaczeck L, Bedke J, Rausch S, Stenzl A Abstract Prostate cancer is a major health issue with an incidence of 1,100,000 worldwide. Eventually, 20-40% of curatively treated patients will face a biochemical recurrence. Lately, the treatment...
Oncology
Thu Jun 25, 2020 15:22
Heating technology for malignant tumors: a review.
Related Articles Heating technology for malignant tumors: a review. Int J Hyperthermia. 2020;37(1):711-741 Authors: Kok HP, Cressman ENK, Ceelen W, Brace CL, Ivkov R, Grüll H, Ter Haar G, Wust P, Crezee J Abstract The therapeutic application of heat is very effective in cancer treatment. Both hyperthermia, i.e., heating to 39-45 °C to induce sensitization to radiotherapy and chemotherapy, and thermal ablation, where temperatures beyond 50 °C...
Oncology
Thu Jun 25, 2020 15:22
Current and future strategies for treatment of ovarian clear cell carcinoma.
Related Articles Current and future strategies for treatment of ovarian clear cell carcinoma. J Obstet Gynaecol Res. 2020 Jun 23;: Authors: Ogasawara A, Sato S, Hasegawa K Abstract Ovarian clear cell carcinoma (OCCC) is one of the five histological types of epithelial ovarian cancer (EOC). OCCC comprises 23% of all EOC cases in Japan, whereas the rate of OCCC in North America and Europe is much lower. OCCC is generally categorized as a rare...
Oncology
Thu Jun 25, 2020 13:53
Palbociclib use with grade 3 neutropenia in hormone receptor-positive metastatic breast cancer.
Related Articles Palbociclib use with grade 3 neutropenia in hormone receptor-positive metastatic breast cancer. Breast Cancer Res Treat. 2020 Jun 23;: Authors: Ham A, Kim MH, Kim GM, Kim JH, Kim JY, Park HS, Park S, Cho YU, Park BW, Kim SI, Sohn J Abstract PURPOSE: Neutropenia is the most common toxicity of CDK4/6 inhibitors, causing frequent dose interruptions. However, CDK4/6 inhibitor-induced neutropenia shows a benign clinical course in...
Oncology
Thu Jun 25, 2020 13:53
Intraductal Therapy in Breast Cancer: Current Status and Future Prospective.
Related Articles Intraductal Therapy in Breast Cancer: Current Status and Future Prospective. J Mammary Gland Biol Neoplasia. 2020 Jun 23;: Authors: Kuang XW, Liu JH, Sun ZH, Sukumar S, Sun SR, Chen C Abstract With our improved understanding of the biological behavior of breast cancer, minimally invasive intervention is urgently needed for personalized treatment of early disease. Intraductal therapy is one such minimally invasive approach. With...
Oncology
Thu Jun 25, 2020 13:53
Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer.
Related Articles Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer. Cancer Metab. 2020;8:11 Authors: Tousignant KD, Rockstroh A, Poad BLJ, Talebi A, Young RSE, Taherian Fard A, Gupta R, Zang T, Wang C, Lehman ML, Swinnen JV, Blanksby SJ, Nelson CC, Sadowski MC Abstract Background: Metabolic reprograming, non-mutational epigenetic changes, increased cell plasticity, and multidrug tolerance are...
Oncology
Thu Jun 25, 2020 13:53
Isolation of cancer-derived extracellular vesicle subpopulations by a size-selective microfluidic platform.
Related Articles Isolation of cancer-derived extracellular vesicle subpopulations by a size-selective microfluidic platform. Biomicrofluidics. 2020 May;14(3):034113 Authors: Chen Z, Yang Y, Yamaguchi H, Hung MC, Kameoka J Abstract Extracellular vesicles (EVs) play an important role in intercellular communication. Recently, there has been increasing interest in EVs as potential diagnostic biomarkers and therapeutic vehicles. However, the molecular...
Oncology
Thu Jun 25, 2020 13:53
Plasma of Acute Lymphoblastic Leukemia Patients React to the Culture of a Mycovirus Containing Aspergillus flavus.
Related Articles Plasma of Acute Lymphoblastic Leukemia Patients React to the Culture of a Mycovirus Containing Aspergillus flavus. J Pediatr Hematol Oncol. 2020 Jul;42(5):350-358 Authors: Tebbi CK, Badiga A, Sahakian E, Arora AI, Nair S, Powers JJ, Achille AN, Jaglal MV, Patel S, Migone F Abstract Acute lymphoblastic leukemia (ALL) is the most common cancer in children and is also seen in adults. Currently, no plasma-based test for the detection...
Oncology
Thu Jun 25, 2020 13:53
Real World Outcomes in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma Receiving Palliative Intent Therapies.
Related Articles Real World Outcomes in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma Receiving Palliative Intent Therapies. Clin Lymphoma Myeloma Leuk. 2020 May 16;: Authors: Ayers EC, Margolis D, Landsburg DJ Abstract BACKGROUND: Outcomes in patients with relapsed/refractory (R/R) diffuse large b-cell lymphoma (DLBCL) who are ineligible for and/or fail high-dose chemotherapy and autologous stem cell transplantation in the...
Oncology
Thu Jun 25, 2020 13:53
Anticancer Activity of Novel NF-κB Inhibitor DHMEQ by Intraperitoneal Administration.
Related Articles Anticancer Activity of Novel NF-κB Inhibitor DHMEQ by Intraperitoneal Administration. Oncol Res. 2020 Jun 23;: Authors: Umezawa K, Breborowicz A, Gantsev S Abstract There have been great advances in the therapy of cancer and leukemia. But there are still many neoplastic diseases that are difficult to treat. For example, it is often difficult to find effective therapies for aggressive cancer and leukemia. Meanwhile, an NF-κB...
Oncology
Thu Jun 25, 2020 13:53

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου

Αρχειοθήκη ιστολογίου