Abstract This study examined the nature and characteristics of sleep‐disordered breathing, including obstructive sleep apnea and central sleep apnea, in patients with post‐stroke dysphagia, to determine the demographic, anthropometric and clinical variables that were associated with sleep‐disordered breathing. Thirty‐nine patients diagnosed with acute stroke (28 males and 11 females with a mean age of 72.3 ± 10.0 years) underwent overnight polysomnography (within 3.9 ± 1.6 days after admission)....
Thu Aug 27, 2020 18:39
Summary Two novel chemotherapeutic chalcones were synthesized and their structures were confirmed by different spectral tools. Theoretical studies such as molecular modeling were done to detect the mechanism of action of these compounds. In vitro cytotoxicity showed a strong effect against all tested cell lines (MCF7, A459, HepG2, and HCT116), and low toxic effect against normal human melanocytes (HFB4). The lung carcinoma cell line was chosen for further molecular studies. Real-time...
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Summary Purpose The CKD4/6 inhibitor abemaciclib is related to adverse events such as hematological toxicity and increase in serum creatinine levels associated with abemaciclib pharmacokinetics. Increase in serum creatinine levels is considered a result of competition with abemaciclib via organic cation transporter 2 and multidrug and toxic compound extrusion. Therefore, we evaluated the association among serum creatinine levels, serum abemaciclib concentrations, and adverse events...
Thu Aug 27, 2020 03:00
Presentation of Case. Dr. Jacob M. Rosenberg: A 53-year-old woman was transferred to this hospital because of progressive headache, gait instability, and weight loss. Approximately 2 months before the patient’s evaluation at this hospital, vertigo developed and resolved spontaneously. One day…
Thu Aug 27, 2020 03:00
Gambling and problem gambling are increasingly being viewed as a public health issue. European surveys have reported a high prevalence of gambling, and according to the Gambling Commission, in 2018, almost hal...
Thu Aug 27, 2020 03:00
The inclusion of authors from diverse backgrounds and with different lived experiences is critical to ensuring the questions addressed in systematic reviews (SRs), as well as the subsequent conclusions and rec...
Thu Aug 27, 2020 03:00
Data from studies with undergraduate and postgraduate taught students suggest that they are at an increased risk of having mental health problems, compared to the general population. By contrast, the literatur...
Wed Aug 26, 2020 03:00
Representing some of the most troublesome agricultural weeds, waterhemp, smooth pigweed, and Palmer amaranth impact crop production systems across the US and elsewhere with ripple effects felt by economies worldwide. In a landmark study, scientists have published the most comprehensive genome information to date for all three species, marking a new era of scientific discovery toward potential solutions.
Thu Aug 27, 2020 17:59
Early Cambrian fossil: Bizarre half-billion-year-old worm with tentacles solves evolutionary mystery
A half-a-billion years old fossil species of marine animal sheds light on how the anatomies of the two main types of an animal group called the hemichordates are related, and provides new evidence in the historical debate among zoologists. The fossils are over half-a-billion years old and were discovered at a Burgess Shale site in the Canadian Rockies.
Thu Aug 27, 2020 21:13
Abstract Objectives The primary aim of the study is to provide recommendations for the investigation and management of patients with new onset loss of sense of smellduring the COVID‐19 pandemic Design After undertaking a literature review, we used the RAND/UCLA methodology with a multi‐step process to reach consensus about treatment options, onward referral andimaging. Setting and participants An expert panel consisting of 15 members was assembled. A literature review was undertaken...
Thu Aug 27, 2020 12:39
Abstract Objectives Manuka honey attacks biofilms, which contribute to bacterial persistence in cystic fibrosis sinusitis. The primary objective was to determine feasibility of investigating manuka honey as an irrigation treatment for cystic fibrosis sinusitis and secondarily to assess the treatment’s preliminary effectiveness. Design Prospective, single‐blinded (clinician only), randomized, parallel two‐armpilot trial. Setting Tertiary rhinology clinic. Participants Subjects...
Thu Aug 27, 2020 18:53
The low fertility of highly weathered soils has been a major problem for resource-constrained smallholder farmers. In central Uganda, smallholder farmers have been collecting termite mound soils anywhere aroun...
Thu Aug 27, 2020 03:00
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease [coronavirus disease 2019 (COVID-19) infection] first appeared in December 2019 in China and is now spreading worldwide. Because SARS-CoV-2 can be transmitted via aerosols and surface contaminations of the environment, appropriate use of anesthesia machines and appropriate behavior in the operation room (OR) are required specifically in relation to this disease. The use of high-performance hydrophobic...
Thu Aug 27, 2020 03:00
Publication date: Available online 27 August 2020Source: Pathology - Research and PracticeAuthor(s): Hyein Ahn, Hyun Ju Lee, Ji-Hye Lee, Hyun Deuk Cho, Mee-Hye Oh, Ji Woong Son, Si-Hyong Jang
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Fuel Medical has partnered with The American Institute of Balance (AIB) to help its audiology and otolaryngology members incorporate, or expand, patient-centered, diagnostic vestibular services. Founded in 1992 by CEO Richard E. Gans, PhD. AIB provides current and scientifically robust clinical protocols and information through its classes, workshops, online education, and certification programs.“We are proud to partner with the largest ENT and medically-based audiology network in the industry....
Thu Aug 27, 2020 16:32
A new study by Auditory Insight found that despite booming consumer interest in online hearing testing, none of the leading tests consistently use best practices to encourage patients to pursue treatment with hearing aids.Hearing aid companies report that patient usage of online hearing tests has increased by as much as 500% since the onset of the coronavirus pandemic in late March 2020. "Online hearing tests are the gateway to care," says Nancy M. Williams, lead study author and Auditory Insight...
Thu Aug 27, 2020 16:28
Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease worldwide in part due to the concomitant obesity pandemic and insulin resistance (IR). It is increasingly becoming evident that NAFLD is a disease affecting numerous extrahepatic vital organs and regulatory pathways. The molecular mechanisms underlying the nonalcoholic steatosis formation are poorly understood, and little information is available on the pathways that are responsible for the progressive hepatocellular...
Thu Aug 27, 2020 15:50
Publication date: Available online 26 August 2020Source: Behavioural Brain ResearchAuthor(s): N. Siminski, S. Böhme, J.B.M. Zeller, M.P.I. Becker, M. Bruchmann, D. Hofmann, F. Breuer, A. Mühlberger, M.A. Schiele, H. Weber, C. Schartner, J. Deckert, P. Pauli, A. Reif, K. Domschke, T. Straube, M.J. Herrmann
Thu Aug 27, 2020 21:49
Publication date: Available online 26 August 2020Source: Behavioural Brain ResearchAuthor(s): Belkis Jacquez, Hyesun Choi, Clark W. Bird, David N. Linsenbardt, C. Fernando Valenzuela
Thu Aug 27, 2020 21:49
Thu Aug 27, 2020 03:00
ObjectivesWheat flour exposure in bakers can elicit respiratory and skin symptoms. Scarce data are available on the prevalence of such conditions in bakers. We investigated the prevalence of work-related rhinitis, asthma-like symptoms and dermatitis in bakers according to job task and type of allergens involved.MethodsOf the 229 traditional bakeries in Verona area who were invited to participate in a cross-sectional survey, 211 (92%) accepted; 727 employees in these bakeries answered a modified version...
Thu Aug 27, 2020 19:01
ObjectiveAmbient air pollution is associated with ischaemic stroke incidence. However, most of the previous studies used stroke-related hospital admission rather than stroke onset itself. This study aimed to evaluate the relationship between ambient air pollutant exposures and acute ischaemic stroke based on the timing of symptom onset.MethodsA time-stratified, case-crossover analysis was performed among 520 patients who had ischaemic stroke admitted to the Second Hospital of Tianjin Medical University...
Thu Aug 27, 2020 19:01
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