Publication date: Available online 28 August 2020Source: Clinical NeurophysiologyAuthor(s): Richard Wennberg, Apameh Tarazi, Dominik Zumsteg, Luis Garcia Dominguez
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Mucosal Immunology, Published online: 29 August 2020; doi:10.1038/s41385-020-00342-xHeme oxygenase-1 inhibition promotes IFNγ- and NOS2-mediated control of Mycobacterium tuberculosis infection
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Publication date: Available online 29 August 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Robert Motl, Dawn Ehde, Lynne Shinto, Bo Fernhall, Nicholas LaRocca, Kathleen Zackowski
Publication date: Available online 27 August 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Thomas J. Barton, David A. Low, Esmee A. Bakker, Thomas Janssen, Sonja de Groot, Lucas van der Woude, Dick H.J. Thijssen
Publication date: Available online 27 August 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Irene Battel, Irene Calvo, Margaret Walshe
Publication date: Available online 27 August 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Tollár József, Ferenc Nagy, Bence Csutorás, Nándor Prontvai, Zsófia Nagy, Katalin Török, Eszter Blényesi, Zsolt Vajda, Dóra Farkas, Béla E. Tóth, Imre Repa, Mariann Moizs, Dávid Sipos, András Kedves, Árpád Kovács, Tibor Hortobágyi
Publication date: Available online 27 August 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Tolu O. Oyesanya, Tim P. Moran, Tamara R. Espinoza, David W. Wright
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Publication date: Available online 28 August 2020Source: Revue des Maladies RespiratoiresAuthor(s): Y. Hassani, S. Ramla, A. Zouak, N. Ahouansou, G. Beltramo, P.-B. Pages, M. Georges, P. Bonniaud
Publication date: Available online 27 August 2020Source: Revue des Maladies RespiratoiresAuthor(s): M. Agossou, D. Holtea-Souty, M. Fore, C. Vuillemin, D. Debieuvre
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Propagation conditions have been shown to be of considerable importance for the fermentation ability of Saccharomyces cerevisiae. The limited tolerance of yeast to inhibitors present in lignocellulosic hydrolysat...
Long non-coding RNA (LncRNA) LINC00525 has been shown to be upregulated in several human cancers and deduced to possess caner regulatory role. The regulation of molecular mechanics of human glioma by lncRNA-LI...
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Publication date: Available online 28 August 2020Source: Magnetic Resonance ImagingAuthor(s): El-Sayed H. Ibrahim, Dhiraj Baruah, Matthew Budde, Jason Rubenstein, Anne Frei, Rachel Schlaak, Elizabeth Gore, Carmen Bergom
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Abstract Sequential digital dermoscopic imaging (SDDI) compares surface microscopy images of skin lesions over multiple timepoints. We utilized a retrospective SDDI cohort to investigate the development of dermoscopic features associated with malignancy in melanoma in situ (MIS). 124 in situ melanomas were assessed from 110 Caucasian patients aged ≥18 years, with ≥2 serial images obtained between 1999–2017 and followed for a mean 41 months (3–142). As a positive control group, 58 invasive melanomas...
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Related Articles The Application of 3D Technology Combined With Image Navigation in Nasal Skull Base Surgery. J Craniofac Surg. 2020 Aug 26;: Authors: Chen M, Xia N, Dong Q, Wen J, Cui X, Yu L, Wei B, Wang Y, Hao D, Jiang Y Abstract Three-dimensional (3D) technology including 3D reconstruction and 3D printing technology, has been widely used in clinical treatment, especially in surgical planning, and image navigation technology, which can make...
Related Articles MOF-derived novel porous Fe3O4@C nanocomposites as smart nanomedical platforms for combined cancer therapy: magnetic-triggered synergistic hyperthermia and chemotherapy. J Mater Chem B. 2020 Aug 28;: Authors: Xiang Z, Qi Y, Lu Y, Hu Z, Wang X, Jia W, Hu J, Ji J, Lu W Abstract Multifunctional nanomedical platforms have broad prospects in imaging-guided combination therapy in cancer precision medicine. In this work, metal-organic...
Related Articles HLA Expression Correlates to the Risk of Immune Checkpoint Inhibitor-Induced Pneumonitis. Cells. 2020 Aug 25;9(9): Authors: Correale P, Saladino RE, Giannarelli D, Sergi A, Mazzei MA, Bianco G, Giannicola R, Iuliano E, Forte IM, Calandruccio ND, Falzea AC, Strangio A, Nardone V, Pastina P, Tini P, Luce A, Caraglia M, Caracciolo D, Mutti L, Tassone P, Pirtoli L, Giordano A, Tagliaferri P Abstract Tumor-infiltrating T cell rescue...
Related Articles Protein glycosylation in head and neck cancers: From diagnosis to treatment. Biochim Biophys Acta Rev Cancer. 2020 Aug 24;:188422 Authors: Rasheduzzaman M, Kulasinghe A, Dolcetti R, Kenny L, Johnson NW, Kolarich D, Punyadeera C Abstract Glycosylation is the most common post-translational modification (PTM) of proteins. Malignant tumour cells frequently undergo an alteration in surface protein glycosylation. This phenomenon is...
Related Articles Gamma ray-induced glial activation and neuronal loss occur before the delayed onset of brain necrosis. FASEB J. 2020 Aug 26;: Authors: He B, Wang X, He Y, Li H, Yang Y, Shi Z, Liu Q, Wu M, Sun H, Xie J, Zhang Z, Yu P, Jiang J, Cheng J, Yang J, Li Y, Lin WJ, Tang Y, Wang X Abstract Radiotherapy is one of the most effective treatments for head and neck tumors. However, delayed radiation-induced brain necrosis (RN) remains a serious...
Related Articles MMP-14 (MT1-MMP) Is a Biomarker of Surgical Outcome and a Potential Mediator of Hearing Loss in Patients With Vestibular Schwannomas. Front Cell Neurosci. 2020;14:191 Authors: Ren Y, Hyakusoku H, Sagers JE, Landegger LD, Welling DB, Stankovic KM Abstract Improved biomarkers are needed for vestibular schwannoma (VS), the most common tumor of the cerebellopontine angle, as existing clinical biomarkers have poor predictive value....
Related Articles Y772 phosphorylation of EphA2 is responsible for EphA2-dependent NPC nasopharyngeal carcinoma growth by Shp2/Erk-1/2 signaling pathway. Cell Death Dis. 2020 Aug 27;11(8):709 Authors: Xiang YP, Xiao T, Li QG, Lu SS, Zhu W, Liu YY, Qiu JY, Song ZH, Huang W, Yi H, Tang YY, Xiao ZQ Abstract EphA2 is an important oncogenic protein and emerging drug target, but the oncogenic role and mechanism of ligand-independent phosphorylation...
Related Articles Epstein-Barr Virus facilitates expression of KLF14 by regulating the cooperative binding of E2F-Rb-HDAC complex in latent infection. J Virol. 2020 Aug 26;: Authors: Pei Y, Wong JH, Jha HC, Tian T, Wei Z, Robertson ES Abstract Epstein-Barr virus (EBV) was discovered as the first human tumor virus more than 50 years ago. EBV infects more than 90% of the human population worldwide and is associated with numerous hematologic malignancies...
Related Articles A novel tumor mutational burden estimation model as a predictive and prognostic biomarker in NSCLC patients. BMC Med. 2020 Aug 26;18(1):232 Authors: Tian Y, Xu J, Chu Q, Duan J, Zhang J, Bai H, Yang Z, Fang W, Cai L, Wan R, Fei K, He J, Gao S, Zhang L, Wang Z, Wang J Abstract BACKGROUND: Tumor mutational burden (TMB) has both prognostic value in resected non-small cell lung cancer (NSCLC) patients and predictive value for immunotherapy...
Related Articles Ventilated Upper Airway Endoscopic Endonasal Procedure Mask: Surgical Safety in the COVID-19 Era. Oper Neurosurg (Hagerstown). 2020 09 01;19(3):271-280 Authors: Helman SN, Soriano RM, Tomov ML, Serpooshan V, Levy JM, Pradilla G, Solares CA Abstract BACKGROUND: COVID-19 poses a risk to the endoscopic skull base surgeon. Significant efforts to improving safety have been employed, including the use of personal protective equipment,...
Related Articles Stretchable ECM Patch Enhances Stem Cell Delivery for Post-MI Cardiovascular Repair. Adv Healthc Mater. 2019 09;8(17):e1900593 Authors: Kim IG, Hwang MP, Park JS, Kim SH, Kim JH, Kang HJ, Subbiah R, Ko UH, Shin JH, Kim CH, Choi D, Park K Abstract Current cell-based therapies administered after myocardial infarction (MI) show limited efficacy due to subpar cell retention in a dynamically beating heart. In particular, cardiac...
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Publication date: Available online 29 August 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Ilona DuBuske, Kristin Schmidlin, Jonathan A. Bernstein
Publication date: Available online 29 August 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Laura Franceschini, Giulia Carli, Giancarlo Landini, Daniela Matarrese, Alessandro Farsi
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Abstract Dent disease is a rare genetic proximal tubulopathy which is under-recognized. Its phenotypic heterogeneity has led to several different classifications of the same disorder, but it is now widely accepted that the triad of symptoms low-molecular-weight proteinuria, hypercalciuria and nephrocalcinosis/nephrolithiasis are pathognomonic of Dent disease. Although mutations on the CLCN5 and OCRL genes are known to cause Dent disease, no such mutations are found in about 25–35%...
Abstract In recent years, large efforts have been made to unravel the role of the gut microbiota in inflammatory bowel disease (IBD), which is a chronic inflammatory disorder of the gastro-intestinal tract. Considering the heterogeneity patients with IBD display in their disease course and response to treatment, there is a big need in translating these findings towards clinical practise. In this perspective article, we discuss strategies to facilitate the transition from basic...
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Publication date: August 2020Source: Médecine & Droit, Volume 2020, Issue 163Author(s):
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Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the safety of ‘Hovenia dulcis fruit extract’ as a novel food (NF) for its use in food supplements. The NF concerns a hot water extract of sliced and dried fruits and peduncles of Hovenia dulcis Thun. The production process is described in sufficient detail but contains contradictory information regarding the mixing with another ingredient...
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Summary Background and aims Infantile hemangiomas can be successfully treated by both systemic propranolol and neodymium:YAG (Nd:YAG)‐dye laser combination therapy. In this retrospective study, the efficacy and safety of sequential and parallel therapy of complicated hemangiomas treated with both methods were evaluated. Patients and methods 30 children with 48 complicated hemangiomas were treated with propranolol and Nd:YAG‐dye laser combination therapy. Using photo comparison, the percentage...
Fri Aug 28, 2020 13:13
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Burkholderia pseudomallei septic arthritis in Type-2 diabetes mellitus patients: Report of two cases
K Baruah Frincy, Borkakoty Biswajyoti, Satyaki Saikia, Manash P Baruah, Utpala DeviIndian Journal of Medical Microbiology 2020 38(2):222-225 Two cases of Burkholderia pseudomallei septic arthritis are presented with a brief review of the literature. B. pseudomallei septic arthritis most commonly occurs in diabetics and other immunocompromised patients and may prove fatal despite appropriate therapy. Clinical and microbiological suspicion of B. pseudomallei infection may help in providing appropriate...
Archana Angrup, Rimjhim Kanaujia, Pallab Ray, Manisha BiswalIndian Journal of Medical Microbiology 2020 38(2):139-143 COVID-19 as a pandemic has spanned across all continents. With the increasing numbers in cases worldwide, even the countries with the best of healthcare facilities are reeling under the burden of the disease. Therefore, in countries with limited access to resources and poor healthcare infrastructure, the low and middle-income countries (LMICs), limiting spread becomes even more...
Jobin John Jacob, Karthick Vasudevan, Balaji Veeraraghavan, Ramya Iyadurai, Karthik GunasekaranIndian Journal of Medical Microbiology 2020 38(2):210-212 Recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and subsequent containment procedures have impacted the world as never seen before. Therefore, there is considerable curiosity about the genome evolution related to the origin, transmission and vaccine impact of this virus. We have analysed genome sequences of SARS-CoV-2...
Sridhar Amalakanti, Kesava Venkata Raman Arepalli, Ravi Kiran KoppoluIndian Journal of Medical Microbiology 2020 38(2):144-151 Context: Coronavirus disease 2019 (CoViD 19) pandemic has induced the government to initiate strict control measures. Improvements to these measures and shortcomings could be gleaned with the understanding of the knowledge, attitude and practices (KAP) of the public. Aims: The aim of this study the CoViD 19 KAP of a south Indian state population. Settings and Design:...
Rahul Narang, Pradeep Deshmukh, Banke Lal SherwalIndian Journal of Medical Microbiology 2020 38(2):137-138
Sanchit Kumar, Bineeta Kashyap, Surinder Kumar, Seema KapoorIndian Journal of Medical Microbiology 2020 38(2):152-156 Purpose: Mycoplasma pneumoniae (M. pneumoniae) and Chlamydophila pneumoniae (C. pneumoniae) play a significant role in children of all ages with lower respiratory tract infections (LRTIs). This study was conducted to detect M. pneumoniae and C. pneumoniae in children with community-acquired LRTIs employing serology, polymerase chain reaction (PCR) and nested PCR analysis. Material...
Sumit Rai, Pramod Kumar Sharma, Nirpex Tyagi, Sugandh AgarwalIndian Journal of Medical Microbiology 2020 38(2):216-218 Staphylococcus aureus and other Gram negative bacteria produce small colony variants (SCV) which usually emerge after exposure to antimicrobials. They cause repeated infections, treatment failures and often pass unnoticed during cultures due to unusual appearance and incomplete incubation. This infectious disease grand round highlights a similar clinical case with atypical history...
Canan Eryildiz, Kiymet Tabakcioglu, Gulcan Kuyucuklu, Nermin SakruIndian Journal of Medical Microbiology 2020 38(2):157-161 Purpose: Campylobacter is one of the most common pathogens that cause food-borne infections worldwide. The aim of this study was to determine the antimicrobial resistance rates and the presence of multiple virulence genes in Campylobacter isolates obtained from humans. Materials and Methods: In this study, 71 Campylobacter isolates obtained from human faecal samples were...
Manisha Paul, Mohit Bhatia, Ranjana Rohilla, Udayakumar Sasirekha, Neelam KaisthaIndian Journal of Medical Microbiology 2020 38(2):229-234 Cryptococcosis is a fungal disease with worldwide distribution and wide array of clinical manifestations, caused by encapsulated basidiomycetous yeasts called Cryptococcus spp. It has traditionally been considered an opportunistic infection known to occur in immunocompromised hosts, particularly those who are infected with human immunodeficiency virus. However,...
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