Related Articles European Expert Opinion on ANT-DBS therapy for patients with drug-resistant epilepsy (a Delphi consensus). Seizure. 2020 Aug 22;81:201-209 Authors: Kaufmann E, Bartolomei F, Boon P, Chabardes S, Colon AJ, Eross L, Fabó D, Gonçalves-Ferreira A, Imbach LL, Van Paesschen W, Peltola J, Rego R, Theys T, Voges B Abstract INTRODUCTION: Although deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS) represents an established...
Related Articles Readiness among people with epilepsy to carry body-worn monitor devices in everyday life: A qualitative study. Epilepsy Behav. 2020 Aug 25;112:107390 Authors: Beck M, Simony C, Zibrandtsen I, Kjaer TW Abstract OBJECTIVE: There have been intensive efforts to design and develop new wearable technology for epileptic seizure detection. Several studies have focused on the technical aspects, but the readiness of patients with epilepsy...
Related Articles Dissociation during Mirror Gazing Test in psychogenic nonepileptic seizures and functional movement disorders. Epilepsy Behav. 2020 Aug 26;112:107368 Authors: Nisticò V, Caputo G, Tedesco R, Marzorati A, Ferrucci R, Priori A, Gambini O, Demartini B Abstract INTRODUCTION: Psychogenic nonepileptic seizures (PNES) and functional movement disorders (FMD) seem to represent the two ends of a continuum where different clinical phenotypes...
Related Articles Comment on: Ketogenic diet therapy provision in the COVID-19 pandemic: Dual-center experience and recommendations. Epilepsy Behav. 2020 Aug 13;112:107399 Authors: Ferraris C, Pasca L, Guglielmetti M, Marazzi C, Trentani C, Varesio C, Tagliabue A, De Giorgis V PMID: 32861023 [PubMed - as supplied by publisher]
Related Articles Trends in lobectomy/amygdalohippocampectomy over time and the impact of hospital surgical volume on hospitalization outcomes: A population-based study. Epilepsia. 2020 Aug 29;: Authors: Kwon CS, Blank L, Mu L, Jetté N Abstract OBJECTIVE: Despite national guidelines supporting surgical referral in drug-resistant epilepsy, it is hypothesized that surgery is underutilized. We investigated the volumes of lobectomy/amygdalohippocampectomy...
Related Articles Centromedian thalamic responsive neurostimulation for Lennox-Gastaut epilepsy and autism. Ann Clin Transl Neurol. 2020 Aug 29;: Authors: Kwon CS, Schupper AJ, Fields MC, Marcuse LV, La Vega-Talbott M, Panov F, Ghatan S Abstract The RNS System is not approved in patients under 18, although a critical need for novel treatment modalities in this vulnerable population persist. We present two pediatric patients with drug-resistant...
Related Articles Integrating quality improvement into the ECHO model to improve care for children and youth with epilepsy. Epilepsia. 2020 Aug 29;: Authors: Joshi S, Gali K, Radecki L, Shah A, Hueneke S, Calabrese T, Katzenbach A, Sachdeva R, Brown L, Kimball E, White P, McManus P, Wood D, Nelson EL, Archuleta P Abstract OBJECTIVE: Project ECHO (Extension for Community Healthcare Outcomes), a telementoring program, utilizes lectures, case-based...
Study of Sexual Dysfunction in People Living with Epilepsy at a Tertiary Care Center of South India.
Related Articles Study of Sexual Dysfunction in People Living with Epilepsy at a Tertiary Care Center of South India. Neurol India. 2020 Jul-Aug;68(4):861-866 Authors: Kumar DP, Wadwekar V, Nair PP, Menon V, Bhatnagar T Abstract Background: The people living with epilepsy (PWE) have a higher prevalence of sexual dysfunction (sexual dysfunction) as compared to the general population. About 20-66% of the PWE develop sexual dysfunction. In spite...
Related Articles Adherence to Antiepileptic Regime: A Cross-sectional Survey. Neurol India. 2020 Jul-Aug;68(4):856-860 Authors: Das AM, Ramamoorthy L, Narayan SK, Wadvekar V, Harichandrakumar KT Abstract Background: Epilepsy is a treatable and curable brain disorder. However major proportion of individuals with this disease in developing countries receives no treatment because of misunderstandings of the public. Other than that, poor adherence...
Related Articles Epileptic seizures of suspected autoimmune origin: a multicentre retrospective study. J Neurol Neurosurg Psychiatry. 2020 Aug 28;: Authors: Bozzetti S, Rossini F, Ferrari S, Delogu R, Cantalupo G, Marchioretto F, Zanette G, Zanoni T, Turatti M, Vitale G, Cadaldini M, Rossi F, Di Tizio L, Zuco C, Maniscalco GT, Soldani F, Monaco S, Trinka E, Hoeftberger R, Mariotto S Abstract OBJECTIVE: To analyse autoantibody status in a well-defined...
Related Articles Preventing Epilepsy After Traumatic Brain Injury: A Propensity Score Analysis. J Chin Med Assoc. 2020 Aug 20;: Authors: Liou JH, Chang YL, Lee HT, Wu MF, Hou YC, Liou WS Abstract BACKGROUND: Due to the potential consequences of Post-traumatic Epilepsy (PTE) exacerbating secondary injury following Traumatic Brain Injury (TBI), the use of Antiepileptic Drugs (AEDs) is an accepted option for seizure prophylaxis. However there is...
Related Articles Relationship between plasma concentrations and clinical effects of perampanel: A prospective observational study. Epilepsy Behav. 2020 Aug 25;112:107385 Authors: Contin M, Pondrelli F, Muccioli L, Mohamed S, Santucci M, Ferri L, Licchetta L, Tinuper P, Bisulli F, Perampanel Study Group Abstract PURPOSE: The purpose of the study was to investigate the potential correlation between plasma concentration of the newer antiseizure...
Related Articles Epilepsy course during COVID-19 pandemic in three Italian epilepsy centers. Epilepsy Behav. 2020 Aug 25;112:107375 Authors: Cabona C, Deleo F, Marinelli L, Audenino D, Arnaldi D, Rossi F, Di Giacomo R, Buffoni C, Rosa GJ, Didato G, Arboscello E, de Curtis M, Villani F Abstract During epidemic outbreaks, epilepsy course can be modified by different physical and psychological stressors and, most importantly, by irregular therapy...
Related Articles Cognitive, behavioral, and social functioning in children and adults with Dravet syndrome. Epilepsy Behav. 2020 Aug 25;112:107319 Authors: Brown A, Arpone M, Schneider AL, Micallef S, Anderson VA, Scheffer IE Abstract AIM: The objective of the study was to delineate the cognitive, behavioral, psychological, and social functioning of individuals with Dravet syndrome. METHOD: Cognitive, behavioral, and social functioning...
Related Articles Significance of determining plasma orexin levels and analysis of related factors for the diagnosis of patients with narcolepsy. Sleep Med. 2020 Jun 30;74:141-144 Authors: Zhu Y, He J, Shi J, Wang Y, Ma L, Gou H, Chen Y, Zhu Y Abstract OBJECTIVES: Decreased cerebrospinal fluid (CSF) orexin levels are one of the diagnostic and classification criteria for narcolepsy. Because of the difficulty in obtaining CSF, its clinical application...
Related Articles Dosage-sensitive genes in autism spectrum disorders: From neurobiology to therapy. Neurosci Biobehav Rev. 2020 Aug 25;: Authors: Javed S, Selliah T, Lee YJ, Huang WH Abstract Autism spectrum disorders (ASDs) are a group of heterogenous neurodevelopmental disorders affecting 1 in 59 children. Syndromic ASDs are commonly associated with chromosomal rearrangements or dosage imbalance involving a single gene. Many of genes are dosage-sensitive...
Related Articles The Changes of Serum Zinc, Copper and Selenium Levels in Epileptic Patients:A Systematic Review and Meta-Analysis. Expert Rev Clin Pharmacol. 2020 Aug 28;: Authors: Jia W, Song Y, Yang L, Kong J, Boczek T, He Z, Wang Y, Zhang X, Hu H, Shao D, Tang H, Xia L, Xu X, Guo F Abstract INTRODUCTION: It is widely accepted that trace elements have been implicated in various metabolic processes. Valproic acid (VPA) is a remarkably safe...
Related Articles Expanding the Neuroimaging Phenotype of Neuronal Ceroid Lipofuscinoses. AJNR Am J Neuroradiol. 2020 Aug 27;: Authors: Biswas A, Krishnan P, Amirabadi A, Blaser S, Mercimek-Andrews S, Shroff M Abstract BACKGROUND AND PURPOSE: Neuronal ceroid lipofuscinoses are a group of neurodegenerative disorders characterized by the accumulation of autofluorescent lipopigments in neuronal cells. As a result of storage material in the brain...
Related Articles Characterization of longitudinal transformation of T2-hyperintensity in oligodendroglioma. BMC Cancer. 2020 Aug 27;20(1):818 Authors: Heiland DH, Ohle R, Cipriani D, Franco P, Delev D, Behriger SP, Kellner E, Petrova G, Neidert N, Mader I, Nuñez MF, Urbach H, Sankowski R, Beck J, Schnell O Abstract BACKGROUND: Oligodendroglioma (ODG) are CNS resistant tumors characterized by their unique molecular signature, namely a combined...
Related Articles Saporin from Saponaria officinalis as a Tool for Experimental Research, Modeling, and Therapy in Neuroscience. Toxins (Basel). 2020 Aug 25;12(9): Authors: Bolshakov AP, Stepanichev MY, Dobryakova YV, Spivak YS, Markevich VA Abstract Saporin, which is extracted from Saponaria officinalis, is a protein toxin that inactivates ribosomes. Saporin itself is non-selective toxin but acquires high specificity after conjugation with different...
Related Articles Refractory epilepsy associated with anti-ribosomal P antibodies successfully treated with topiramate. J Neuroimmunol. 2020 03 15;340:577144 Authors: Uribe-San-Martín R, Ciampi E, Cruz JP, Vásquez M, Cárcamo C Abstract We report the case of a 25-year-old woman who developed temporal lobe epilepsy associated with systemic lupus erythematosus (SLE). Serum and cerebrospinal fluid samples showed high titers of anti-ribosomal P (anti-P)...
Related Articles Lipidomic characteristics and clinical findings of epileptic patients treated with valproic acid. J Cell Mol Med. 2019 09;23(9):6017-6023 Authors: Li R, Qin X, Liang X, Liu M, Zhang X Abstract Our early study has found valproic acid (VPA)-induced lipid dysmetabolism in animal model, however, the details of lipid profiling of VPA-treated epileptic patients remain unknown. Therefore, in this study, the blood samples of VPA-treated...
32 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: epilepsy treatment These pubmed results were generated on 2020/08/28PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related Articles Achieving Efficacious Immunotherapy for Patients with Glioblastoma. Expert Rev Anticancer Ther. 2020 Aug 27;: Authors: Young JS PMID: 32852237 [PubMed - as supplied by publisher]
Novel treatments using PD1 inhibitors for advanced and metastatic cutaneous squamous cell carcinoma.
Related Articles Novel treatments using PD1 inhibitors for advanced and metastatic cutaneous squamous cell carcinoma. Expert Rev Anticancer Ther. 2020 Aug 27;: Authors: Pezeshki S, Hemmati S, Rezaei N PMID: 32852235 [PubMed - as supplied by publisher]
Related Articles The effects of exercise on cancer-related fatigue in breast cancer patients during primary treatment: a meta-analysis and systematic review. Expert Rev Anticancer Ther. 2020 Aug 26;: Authors: Ehlers DK, DuBois K, Salerno EA Abstract INTRODUCTION: Cancer-related fatigue is one of the most prevalent symptoms reported by breast cancer survivors. Despite a corpus of literature dedicated to understanding and identifying evidence-based...
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Related Articles A special collection of reviews on frontiers in immunology. Cell Res. 2020 Aug 28;: Authors: Xu C, Li HB, Flavell RA PMID: 32859992 [PubMed - as supplied by publisher]
Related Articles A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis. Proc Natl Acad Sci U S A. 2020 Aug 28;: Authors: Ramesh A, Schubert RD, Greenfield AL, Dandekar R, Loudermilk R, Sabatino JJ, Koelzer MT, Tran EB, Koshal K, Kim K, Pröbstel AK, Banerji D, University of California, San Francisco MS-EPIC Team, Guo CY, Green AJ, Bove RM, DeRisi JL, Gelfand JM, Cree BAC, Zamvil SS, Baranzini SE, Hauser SL, Wilson MR Abstract...
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65 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: frontiers in neuroscience These pubmed results were generated on 2020/08/28PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related Articles Cerebrospinal fluid phosphorylated neurofilament heavy chain and chitotriosidase in primary lateral sclerosis. J Neurol Neurosurg Psychiatry. 2020 Aug 27;: Authors: Verde F, Zaina G, Bodio C, Borghi MO, Soranna D, Peverelli S, Ticozzi N, Morelli C, Doretti A, Messina S, Maderna L, Colombrita C, Gumina V, Tiloca C, Meroni PL, Zambon A, Ratti A, Silani V PMID: 32855294 [PubMed - as supplied by publisher]
Related Articles Mediator Med23 Regulates Adult Hippocampal Neurogenesis. Front Cell Dev Biol. 2020;8:699 Authors: Chen GY, Zhang S, Li CH, Qi CC, Wang YZ, Chen JY, Wang G, Ding YQ, Su CJ Abstract Mammalian Mediator (Med) is a key regulator of gene expression by linking transcription factors to RNA polymerase II (Pol II) transcription machineries. The Mediator subunit 23 (Med23) is a member of the conserved Med protein complex and plays essential...
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Related Articles Cognitive functioning, patient health communication, and worry mediate pain predictive effects on health-related quality of life in youth with sickle cell disease. Pediatr Blood Cancer. 2020 Aug 29;:e28680 Authors: Varni JW, Panepinto JA Abstract OBJECTIVES: The objective was to investigate the serial mediating effects of perceived cognitive functioning, patient health communication, and disease-specific worry in the relationship...
Related Articles The effect of exercise training on cardiometabolic health in men with prostate cancer receiving androgen deprivation therapy: a systematic review and meta-analysis. Prostate Cancer Prostatic Dis. 2020 Aug 28;: Authors: Bigaran A, Zopf E, Gardner J, La Gerche A, Murphy DG, Howden EJ, Baker MK, Cormie P Abstract BACKGROUND: Growing evidence suggests that men exposed to androgen deprivation therapy (ADT) have an increased...
Related Articles Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity. Nat Commun. 2020 Aug 28;11(1):4324 Authors: Grabovska Y, Mackay A, O'Hare P, Crosier S, Finetti M, Schwalbe EC, Pickles JC, Fairchild AR, Avery A, Cockle J, Hill R, Lindsey J, Hicks D, Kristiansen M, Chalker J, Anderson J, Hargrave D, Jacques TS, Straathof K, Bailey S, Jones C, Clifford SC, Williamson D Abstract...
Related Articles Assessment of tumor suppressor promoter methylation in healthy individuals. Clin Epigenetics. 2020 Aug 28;12(1):131 Authors: Poduval DB, Ognedal E, Sichmanova Z, Valen E, Iversen GT, Minsaas L, Lønning PE, Knappskog S Abstract BACKGROUND: The number of tumor suppressor genes for which germline mutations have been linked to cancer risk is steadily increasing. However, while recent reports have linked constitutional normal...
Related Articles Prognostic role of pre-sarcopenia and body composition with long-term outcomes in obstructive colorectal cancer: a retrospective cohort study. World J Surg Oncol. 2020 Aug 28;18(1):230 Authors: Lee CS, Won DD, Oh SN, Lee YS, Lee IK, Kim IH, Choi MH, Oh ST Abstract BACKGROUND: The clinical significance of pre-sarcopenia in colorectal cancer obstruction has not yet been described. The present study aimed to determine the...
29 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/08/29PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
55 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/08/28PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related Articles Carboplatin dose capping affects pCR rate in HER2-positive breast cancer patients treated with neoadjuvant Docetaxel, Carboplatin, Trastuzumab, Pertuzumab (TCHP). Breast Cancer Res Treat. 2020 Aug 29;: Authors: Howell SJ, Coe F, Wang X, Horsley L, Ekholm M Abstract PURPOSE: Estimated glomerular filtration rate (eGFR) is commonly used to calculate carboplatin doses and capping the eGFR may be used to reduce the risk of excessive...
Related Articles Clinical implications of HER2 mRNA expression and intrinsic subtype in refractory HER2-positive metastatic breast cancer treated with pan-HER inhibitor, poziotinib. Breast Cancer Res Treat. 2020 Aug 28;: Authors: Kim JY, Park K, Im SA, Jung KH, Sohn J, Lee KS, Kim JH, Yang Y, Park YH Abstract INTRODUCTION: We explored clinical implication of intrinsic molecular subtype in human epidermal growth factor receptor 2 (HER2) + metastatic...
Related Articles Trastuzumab: More than a Guide in HER2-Positive Cancer Nanomedicine. Nanomaterials (Basel). 2020 Aug 26;10(9): Authors: Nieto C, Vega MA, Martín Del Valle EM Abstract HER2 overexpression, which occurs in a fifth of diagnosed breast cancers as well as in other types of solid tumors, has been traditionally linked to greater aggressiveness. Nevertheless, the clinical introduction of trastuzumab has helped to improve HER2-positive...
Related Articles Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer. J Nanobiotechnology. 2020 Aug 27;18(1):118 Authors: Cheng YA, Wu TH, Wang YM, Cheng TL, Chen IJ, Lu YC, Chuang KH, Wang CK, Chen CY, Lin RA, Chen HJ, Liao TY, Liu ES, Chen FM Abstract BACKGROUND: Developing a universal strategy to improve the specificity and sensitivity of PEGylated...
Related Articles Cost-Effectiveness of Tucatinib in Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer From the US and Chinese Perspectives. Front Oncol. 2020;10:1336 Authors: Wu Q, Liao W, Zhang M, Huang J, Zhang P, Li Q Abstract Background: The clinical evaluation of HER2CLIMB trial showed a 21. 9-month median overall survival with the triplet regimens of tucatinib, capecitabine, and trastuzumab (TXT) for patients with...
Related Articles Design and evaluation of scFv-RTX-A as a novel immunotoxin for breast cancer treatment: an in silico approach. J Immunoassay Immunochem. 2020 Aug 26;:1-15 Authors: Samavarchi Tehrani S, Gharibi S, Movahedpour A, Goodarzi G, Jamali Z, Khatami SH, Maniati M, Ranjbar M, Shabaninejad Z, Savardashtaki A, Taheri-Anganeh M Abstract Human epidermal growth factor receptor 2 (HER2) is overexpressed in breast cancer (BC) patients. Hence,...
Related Articles PIK3CA mutation in the ShortHER randomized adjuvant trial for patients with early HER2+ breast cancer: association with prognosis and integration with PAM50 subtype. Clin Cancer Res. 2020 Aug 25;: Authors: Guarneri V, Dieci MV, Bisagni G, Brandes AA, Frassoldati A, Cavanna L, Musolino A, Giotta F, Rimanti A, Garrone O, Bertone E, Cagossi K, Nanni O, Piacentini F, Orvieto E, Griguolo G, Curtarello M, Urso L, Paré L, Chic N, D'Amico R, Prat A,...
Related Articles Paraneoplastic cerebellar degeneration diagnosed by anti-Yo determination in a young woman with early breast cancer. BMJ Case Rep. 2020 Aug 24;13(8): Authors: Mirallas O, Rezqallah Arón MA, Saoudi Gonzalez N, Escrivá-de-Romaní S Abstract A 44-year-old woman diagnosed with a HER2 positive early breast cancer, receiving neoadjuvant treatment with paclitaxel and targeted agents, trastuzumab together with pertuzumab, presented to...
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Related Articles Multiparametric functional MRI and 18F-FDG-PET for survival prediction in patients with head and neck squamous cell carcinoma treated with (chemo)radiation. Eur Radiol. 2020 Aug 26;: Authors: Martens RM, Koopman T, Lavini C, Ali M, Peeters CFW, Noij DP, Zwezerijnen G, Marcus JT, Vergeer MR, Leemans CR, de Bree R, de Graaf P, Boellaard R, Castelijns JA Abstract OBJECTIVES: To assess (I) correlations between diffusion-weighted...
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Related Articles Prebiotic administration modulates gut microbiota and faecal short-chain fatty acid concentrations but does not prevent chronic intermittent hypoxia-induced apnoea and hypertension in adult rats. EBioMedicine. 2020 Aug 26;59:102968 Authors: O'Connor KM, Lucking EF, Bastiaanssen TFS, Peterson VL, Crispie F, Cotter PD, Clarke G, Cryan JF, O'Halloran KD Abstract BACKGROUND: Evidence is accruing to suggest that microbiota-gut-brain...
Related Articles Power spectral densities of nocturnal pulse oximetry signals differ in OSA patients with and without daytime sleepiness. Sleep Med. 2020 Jul 20;73:231-237 Authors: Kainulainen S, Töyräs J, Oksenberg A, Korkalainen H, Afara IO, Leino A, Kalevo L, Nikkonen S, Gadoth N, Kulkas A, Myllymaa S, Leppänen T Abstract BACKGROUND: As nocturnal hypoxemia and heart rate variability are associated with excessive daytime sleepiness (EDS) related...
Related Articles White matter alterations in patients with obstructive sleep apnea: a systematic review of diffusion MRI studies. Sleep Med. 2020 Jun 29;75:236-245 Authors: Rostampour M, Noori K, Heidari M, Fadaei R, Tahmasian M, Khazaie H, Zarei M Abstract BACKGROUND: Obstructive sleep apnea (OSA) is a common sleep disorder, which causes wide range of neurological and psychiatric symptoms. Several studies demonstrated structural and functional...
Related Articles A multidisciplinary weight loss intervention in obese adolescents with and without sleep-disordered breathing improves cardiometabolic health, whether SDB was normalized or not. Sleep Med. 2020 Jun 30;75:225-235 Authors: Roche J, Corgosinho FC, Isacco L, Scheuermaier K, Pereira B, Gillet V, Moreira GA, Pradella-Hallinan M, Tufik S, de Mello MT, Mougin F, Dâmaso AR, Thivel D Abstract OBJECTIVES: Pediatric obesity and sleep-disordered...
Related Articles High sleep-related breathing disorders among HIV-infected patients with sleep complaints. Sleep Med. 2020 Jul 20;75:218-224 Authors: Chen CC, Lin CY, Chen YC, Ko WC, Li CY, Ko NY Abstract BACKGROUND: Sleep-related breathing disorders (SRBD) not only adversely impact cardiovascular and pulmonary functions but also reduce the quality of life. This study attempted to investigate the severity and related factors of SRBD among human...
Related Articles Effect of myofunctional therapy on children with obstructive sleep apnea: a meta-analysis. Sleep Med. 2020 Aug 10;75:210-217 Authors: Bandyopadhyay A, Kaneshiro K, Camacho M Abstract OBJECTIVE: To systematically review the current literature for articles describing the effect of myofunctional therapy on pediatric obstructive sleep apnea (OSA) and to perform a meta-analysis on the sleep study data. METHODS: Three authors...
Related Articles Evaluation of late atrial enhancement by cardiac magnetic resonance imaging in patients with obstructive sleep apnea. Sleep Med. 2020 Jul 01;74:204-210 Authors: de Oliveira FG, Pinto I, Valdigem B, Senra T, Bertolami A Abstract INTRODUCTION: Atrial fibrillation (AF) is a growing public health problem especially due to its association with thromboembolic phenomena. Among its risk factors, obstructive sleep apnea (OSA) has increased...
Related Articles Obstructive Sleep Apnea and Its Treatment in Aging: Effects on Alzheimer's disease Biomarkers, Cognition, Brain Structure and Neurophysiology. Neurobiol Dis. 2020 Aug 26;:105054 Authors: Mullins AE, Kam K, Parekh A, Bubu OM, Osorio RS, Varga AW Abstract Here we review the impact of obstructive sleep apnea (OSA) on biomarkers of Alzheimer's disease (AD) pathogenesis, neuroanatomy, cognition and neurophysiology, and present the...
Related Articles Systemic Inflammation as a Moderator Between Sleep and Incident Dementia. Sleep. 2020 Aug 29;: Authors: Baril AA, Beiser AS, Redline S, McGrath ER, Aparicio HJ, Gottlieb DJ, Seshadri S, Pase MP, Himali JJ Abstract STUDY OBJECTIVES: To determine whether C-reactive protein (CRP), a marker of systemic inflammation, moderates the association between sleep and incident dementia. METHODS: We studied Framingham Heart Study...
Related Articles Small airways' function in Obstructive Sleep Apnea-Hypopnea Syndrome. Pulmonology. 2020 Aug 26;: Authors: Giannadaki K, Schiza S, Vavougios G, Ladopoulos V, Tzanakis N, Siafakas N Abstract INTRODUCTION AND OBJECTIVES: Most of the studies of the pathophysiology of Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) focus on the collapsibility and obstruction of the upper airways. The aim of our study was the investigation of small...
Related Articles Standardized reporting of co-morbidity outcome after bariatric surgery: low compliance with the ASMBS outcome reporting standards despite ease of use. Surg Obes Relat Dis. 2020 Jul 19;: Authors: Burger PM, Monpellier VM, Deden LN, Kooiman LBR, Liem RSL, Hazebroek EJ, Janssen IMC, Westerink J Abstract BACKGROUND: Despite the publication of the American Society for Metabolic and Bariatric Surgery (ASMBS) Outcome Reporting Standards...
Related Articles The role of sleep endoscopy in oral appliance therapy for obstructive sleep apnea. Auris Nasus Larynx. 2020 Aug 25;: Authors: Koutsourelakis I, Kontovazainitis G, Lamprou K, Gogou E, Samartzi E, Tzakis M Abstract OBJECTIVE: Although oral appliance therapy is considered a validated treatment for obstructive sleep apnea, its therapeutic success varies significantly among patients. Drug-induced sleep endoscopy is often employed...
Related Articles Long-term positive airway pressure therapy is associated with reduced total cholesterol levels in patients with obstructive sleep apnea: data from the European Sleep Apnea Database (ESADA). Sleep Med. 2020 Mar 07;75:201-209 Authors: Gunduz C, Basoglu OK, Kvamme JA, Verbraecken J, Anttalainen U, Marrone O, Steiropoulos P, Roisman G, Joppa P, Hein H, Trakada G, Hedner J, Grote L, European Sleep Apnea Database collaborators Abstract ...
Related Articles Relationship between reflux diseases and obstructive sleep apnea together with continuous positive airway pressure treatment efficiency analysis. Sleep Med. 2020 Aug 05;75:151-155 Authors: Wang L, Han H, Wang G, Liu H, Sun Z, Li B, Sui X, Du F, Zhong C, Wu W Abstract BACKGROUND: Obstructive sleep apnea (OSA) is known to be highly associated with reflux diseases. There is evidence that continuous positive airway pressure (CPAP)...
Related Articles Sleep bruxism and its associations with insomnia and OSA in the general population of Sao Paulo. Sleep Med. 2020 Jun 20;75:141-148 Authors: Maluly M, Dal Fabbro C, Andersen ML, Herrero Babiloni A, Lavigne GJ, Tufik S Abstract Sleep bruxism (SB) is characterized by recurrent masticatory muscle activity during sleep with occasional tooth grinding. SB can be concomitant with sleep apnea although its association with insomnia is...
Related Articles Sleep-related leg movements in obstructive sleep apnea: definitions, determinants, and clinical consequences. Sleep Med. 2020 Jun 10;75:131-140 Authors: Schipper MH, Alvarez-Estevez D, Jellema K, Verbraecken J, Fulda S, Rijsman RM Abstract STUDY OBJECTIVES: To investigate (1) the effect of different scoring rules on leg movement (LM) classification in patients with obstructive sleep apnea (OSA); (2) determinants of respiratory...
Related Articles Bidirectional association between alopecia areata and sleep disorders: a population-based cohort study in Taiwan. Sleep Med. 2020 Jun 14;75:112-116 Authors: Dai YX, Tai YH, Chen CC, Chang YT, Chen TJ, Chen MH Abstract BACKGROUND: The relationship between alopecia areata (AA) and sleep disorders remains uncertain. This study aims to investigate the bidirectional association between AA and sleep disorders. METHODS: To...
Related Articles Association between sleep disordered breathing and symptoms of attention deficits in adults: a systematic review. Sleep Med. 2020 Jul 03;73:223-230 Authors: Polmann H, Réus JC, Maia I, Dick BD, Gozal D, Flores-Mir C, Porporatti AL, De Luca Canto G Abstract BACKGROUND: In light of previous reported associations between sleep disordered breathing (SDB) and symptoms of attention deficits, the aim of this systematic review (SR)...
Related Articles Pulse oximetric routine examination of sleep apnea in acute stroke (PRESS). Sleep Med. 2020 Jul 18;73:208-212 Authors: Šiarnik P, Jurík M, Veverka J, Klobučníková K, Kollár B, Turčáni P, Sýkora M Abstract BACKGROUND: Sleep-disordered breathing (SDB) is present in more than 70% of stroke patients. Despite its association with increased morbidity, mortality, and reduced functional outcomes, targeted assessment of SDB in stroke...
Related Articles Sleep disorders are distinctively associated with exercise intolerance and sedentary behavior in children with cystic fibrosis. Sleep Med. 2020 Jul 18;74:145-151 Authors: Barbosa RRB, Coelho PF, Liberato FMG, Vidal PDR, Couto Olimpio de Carvalho RB, Melotti RCNC, Donadio MVF Abstract OBJECTIVE: To evaluate the presence of sleep disorders and its associations with exercise capacity and daily physical activity levels among children...
Related Articles Obstructive sleep apnea, shift work and cardiometabolic risk. Sleep Med. 2020 May 18;74:132-140 Authors: Santos I, Rocha I, Gozal D, Meira E Cruz M Abstract Obstructive Sleep Apnea (OSA) is one of the most common sleep disorders, and invokes numerous negative health-related outcomes and physiopathological processes. Understanding the mechanisms by which OSA potentiates cardiometabolic risk of patients remains a current challenge....
Related Articles Weight Gain Induced by Continuous Positive Airway Pressure in Patients with Obstructive Sleep Apnea is Mediated by Fluid Accumulation: A Randomized Cross-Over Controlled Trial. Am J Respir Crit Care Med. 2020 Aug 28;: Authors: Herculano S, Grad GF, Drager LF, de Albuquerque ALP, Melo CM, Lorenzi-Filho G, Genta PR PMID: 32857590 [PubMed - as supplied by publisher]
Related Articles Impact of CPAP treatment for obstructive sleep apnea on visceral adipose tissue: a meta-analysis of randomized controlled trials. Sleep Breath. 2020 Aug 28;: Authors: Chen Q, Lin G, Chen Y, Wu C, Li C, Huang J, Lin Q Abstract BACKGROUND: It is still controversial if the continuous positive airway pressure (CPAP) treatment for patients with obstructive sleep apnea (OSA) can markedly influence an effect on visceral adipose tissue...
Related Articles What every dentist needs to know about obstructive sleep apnea. Gen Dent. 2020 Sep-Oct;68(5):30-34 Authors: Votolato GS, Henry JK, Brooks JK, Cohen L, Bashirelahi N Abstract Sleep apnea has 2 variants that are classified by their etiologic mechanism, namely, an obstructive or a central origin. Despite the clinical and scientific advancements in obstructive sleep apnea (OSA) over the past 20 years, a majority of affected patients...
Related Articles Sleep-disordered breathing in patients with stroke-induced dysphagia. J Sleep Res. 2020 Aug 27;:e13179 Authors: Estai M, Walsh J, Maddison K, Shepherd K, Hillman D, McArdle N, Baker V, King S, Al-Obaidi Z, Bamagoos A, Parry R, Langdon C, Trzaskowski R, Harris G, Brookes K, Blacker D, Eastwood PR Abstract This study examined the nature and characteristics of sleep-disordered breathing, including obstructive sleep apnea and central...
Related Articles Obstructive Sleep Apnea: Risk Factor for Arrhythmias, Conduction Disorders, and Cardiac Arrest. Cureus. 2020 Aug 24;12(8):e9992 Authors: Acharya R, Basnet S, Tharu B, Koirala A, Dhital R, Shrestha P, Poudel D, Ghimire S, Kafle S Abstract Background Obstructive sleep apnea (OSA) has been described as a risk factor for cardiac arrhythmias. Its association with atrial fibrillation has been established. However, relationships with...
Related Articles Modified reposition pharyngoplasty for OSAS treatment: How we do it and our results. Acta Otorrinolaringol Esp. 2020 Aug 24;: Authors: Carrasco Llatas M, Valenzuela Gras M, Martínez Ruiz de Apodaca P, Dalmau Galofre J Abstract INTRODUCTION AND PURPOSES: The relevance of the lateral pharyngeal walls in the collapse of the upper airway in obstructive sleep apnea patients has been revealed in the last 20years. New surgical techniques...
Related Articles Evaluation of prefabricated adjustable thermoplastic mandibular advancement devices (PAT-MADs) for obstructive sleep apnea: an Asian experience. Sleep Med. 2020 Mar 07;75:96-102 Authors: Soh L, Han HJ, Yue Y, Tay JY, Hao Y, Toh ST Abstract OBJECTIVE: To evaluate the use of direct to consumer Prefabricated adjustable thermoplastic mandibular advancement devices (PAT-MADs) (MyTAP™, Airway Management Inc), its effectiveness in...
Related Articles Waking EEG functional connectivity in middle-aged and older adults with obstructive sleep apnea. Sleep Med. 2020 Jun 14;75:88-95 Authors: Fortin M, Lina JM, Desjardins MÈ, Gagnon K, Baril AA, Carrier J, Gosselin N Abstract OBJECTIVES: The present study aimed at investigating changes in waking electroencephalography (EEG), most specifically regarding spectral power and functional connectivity, in middle-aged and older adults...
Related Articles The impact of continuous positive airway pressure therapy on circulating levels of malondialdehyde: a systematic review and meta-analysis. Sleep Med. 2020 Feb 26;75:27-36 Authors: Fadaei R, Koushki M, Sharafkhaneh A, Moradi N, Ahmadi R, Rostampour M, Khazaie H Abstract BACKGROUND: Obstructive sleep apnea (OSA) is a highly prevalent sleep disorder which associated with increased oxidative stress and cardiovascular diseases. Malondialdehyde...
Related Articles Perception of sleep duration in adult patients with suspected obstructive sleep apnea. PLoS One. 2020;15(8):e0238083 Authors: Duarte RLM, Mendes BA, Oliveira-E-Sá TS, Magalhães-da-Silveira FJ, Gozal D Abstract PURPOSE: Discrepancies between subjective and objective measures of total sleep time (TST) are frequent among insomnia patients, but this issue remains scarcely investigated in obstructive sleep apnea (OSA). We aimed to...
Related Articles Correlation Between QTc Prolongation and Obstructive Sleep Apnea in Patients with Type 2 Diabetes Mellitus. Med Sci Monit. 2020 Aug 27;26:e926954 Authors: Shi H, Jiang X Abstract BACKGROUND Obstructive sleep apnea (OSA) plays an important role in the progression of cardiovascular disease (CVD), and is a common symptom in patients with type 2 diabetes mellitus (T2DM). Prolongation of corrected QT interval (QTc) reflects ventricular...
Related Articles Prospective Correlation of Risk of Obstructive Sleep Apnea With Severe Clinical Features of Thyroid Eye Disease. Ophthalmic Plast Reconstr Surg. 2020 Aug 24;: Authors: Godfrey KJ, Schmuter G, Hu B, Tooley AA, Dunbar KE, Basner RC, Kazim M Abstract PURPOSE: To evaluate the association between risk of obstructive sleep apnea (OSA) and severity of thyroid eye disease (TED) using a validated OSA screening tool. METHODS:...
Related Articles Pulmonary hypertension and chronic hypoventilation in ROHHAD syndrome treated with average-volume assured pressure support. Pediatr Investig. 2019 Dec;3(4):253-256 Authors: Stowe RC, Afolabi-Brown O Abstract Introduction: Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD) syndrome is an exceptionally rare clinical entity with significant morbidity and high mortality with...
Related Articles Updates on management of pediatric obstructive sleep apnea. Pediatr Investig. 2019 Dec;3(4):228-235 Authors: Yu JL, Afolabi-Brown O Abstract Obstructive sleep apnea (OSA) affects about 1%-5% of the pediatric population. The consequences of untreated OSA in children include neurocognitive deficits, behavioral problems, poor school performance as well as systemic and pulmonary hypertension. The treatment options for pediatric...
Related Articles Ambulatory blood pressure monitoring in children with obstructive sleep apnea syndrome. Pediatr Investig. 2019 Dec;3(4):217-222 Authors: Geng X, Wu Y, Ge W, Feng G, Zheng L, Xu Z, Ni X Abstract Importance: The incidence of obstructive sleep apnea syndrome (OSAS) in children has increased year by year recently. Blood pressure research of OSAS children can help understand the occurrence of OSAS related complications. Early detection...
Related Articles Intrahepatic Expression of Fatty Acid Translocase CD36 Is Increased in Obstructive Sleep Apnea. Front Med (Lausanne). 2020;7:450 Authors: Rey E, Del Pozo-Maroto E, Marañón P, Beeler B, García-García Y, Landete P, Isaza SC, Farré R, García-Monzón C, Almendros I, González-Rodríguez Á Abstract Nocturnal intermittent hypoxia (IH) featuring obstructive sleep apnea (OSA) dysregulates hepatic lipid metabolism and might contribute to...
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Related Articles Insomnia and obstructive sleep apnea as potential triggers of dementia: is personalized prediction and prevention of the pathological cascade applicable? EPMA J. 2020 Sep;11(3):355-365 Authors: Kitamura T, Miyazaki S, Sulaiman HB, Akaike R, Ito Y, Suzuki H Abstract Introduction: Sleep disorders ultimately result in sleep deficiency and poor-quality adversely impacts the immune system, glucose metabolism, body weight control,...
Related Articles Aberrant Awake Spontaneous Brain Activity in Obstructive Sleep Apnea: A Review Focused on Resting-State EEG and Resting-State fMRI. Front Neurol. 2020;11:768 Authors: Wu Y, Zhao W, Chen X, Wan X, Lei X Abstract As one of the most common sleep-related respiratory disorders, obstructive sleep apnea (OSA) is characterized by excessive snoring, repetitive apnea, arousal, sleep fragmentation, and intermittent nocturnal hypoxemia....
Related Articles Sleep Disorders in Leucine-Rich Glioma-Inactivated Protein 1 and Contactin Protein-Like 2 Antibody-Associated Diseases. Front Neurol. 2020;11:696 Authors: Lin N, Hao H, Guan H, Sun H, Liu Q, Lu Q, Jin L, Ren H, Huang Y Abstract Objective: Sleep disorders are common in voltage-gated potassium channel complex antibody (VGKC-Ab) diseases. The aim was to investigate the sleep disturbances and polysomnography (PSG) characteristics...
Related Articles Sudden death in individuals with obstructive sleep apnoea: protocol for a systematic review and meta-analysis. BMJ Open. 2020 Aug 26;10(8):e039774 Authors: Heilbrunn E, Ssentongo P, Chinchilli VM, Ssentongo AE Abstract INTRODUCTION: Obstructive sleep apnoea (OSA) is a form of sleep-disordered breathing, characterised by blockage of the airway, snoring, gasping for air during sleep, daytime sleepiness and fatigue. OSA is associated...
Related Articles A novel algorithm to predict oxygen desaturation in sedated patients with obstructive sleep apnea utilizing polysomnography: A STROBE-compliant article. Medicine (Baltimore). 2020 Aug 21;99(34):e21915 Authors: Chiang MH, Luo SD, Lin HC, Hou SY, Ke TY, Chen CC, Hung KC, Wu SC Abstract This retrospective study aimed at identifying the predictors of oxygen desaturation (OD) (i.e., SpO2 < 95%) in patients with obstructive sleep...
Related Articles Obstructive sleep apnea hypopnea syndrome: Protocol for the development of a core outcome set. Medicine (Baltimore). 2020 Aug 21;99(34):e21591 Authors: Wanyan P, Wang J, Wang W, Kong Y, Liang Y, Liu W, Yu Q Abstract BACKGROUND: Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common, chronic sleep disease. As the incidence of OSAHS increases, it has seriously threatened people's health. There have been an increasing number...
Related Articles Prevalence and correlates of obstructive sleep apnea in urban-dwelling, low-income, predominantly African-American women. Sleep Med. 2020 Jun 29;73:187-195 Authors: Dong L, Dubowitz T, Haas A, Ghosh-Dastidar M, Holliday SB, Buysse DJ, Hale L, Gary-Webb TL, Troxel WM Abstract STUDY OBJECTIVES: The current study examined the prevalence and correlates of obstructive sleep apnea in a sample of low-income, predominantly African-American...
Related Articles Feasibility of electronic sleep disorder screening in healthcare workers of a large healthcare system. Sleep Med. 2020 Aug 04;73:181-186 Authors: Pascoe M, Alberts J, Wang L, Bruton M, Rogen B, Rehm SJ, McHugh L, Katzan I, Foldvary-Schaefer N Abstract STUDY OBJECTIVES: Many healthcare workers live with sleep disorders and may be unaware of their condition. We aimed to ascertain sleep disorder symptoms including high-risk obstructive...
Related Articles Impaired intestinal barrier in patients with obstructive sleep apnea. Sleep Breath. 2020 Aug 26;: Authors: Li Q, Xu T, Zhong H, Gao W, Shao C, Feng L, Li T Abstract BACKGROUND: Obstructive sleep apnea (OSA) is often associated with multisystem damage. The gut is a pivotal organ that initiates the pathophysiological processes of multisystem diseases. Intermittent hypoxia resulting from OSA may impair the intestinal barrier prior...
Related Articles Obstructive sleep apnea, chronic obstructive pulmonary disease and NAFLD: an individual participant data meta-analysis. Sleep Med. 2020 Apr 22;: Authors: Jullian-Desayes I, Trzepizur W, Boursier J, Joyeux-Faure M, Bailly S, Benmerad M, Le Vaillant M, Jaffre S, Pigeanne T, Bizieux-Thaminy A, Humeau MP, Alizon C, Goupil F, Costentin C, Gaucher J, Tamisier R, Gagnadoux F, Pépin JL Abstract RATIONALE: Chronic intermittent hypoxia...
Related Articles Baclofen, insomnia and sleep apnea: a dangerous triad? Sleep Med. 2020 Aug 06;: Authors: Revol B, Jullian-Desayes I, Tamisier R, Joyeux-Faure M, Pépin JL PMID: 32843297 [PubMed - as supplied by publisher]
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